Zixiao Yin, Huiling Yu, Tianshuo Yuan, Clay Smyth, Md Fahim Anjum, Guanyu Zhu, Ruoyu Ma, Yichen Xu, Qi An, Yifei Gan, Timon Merk, Guofan Qin, Hutao Xie, Ning Zhang, Chunxue Wang, Yin Jiang, Fangang Meng, Anchao Yang, Wolf-Julian Neumann, Philip Starr, Simon Little, Luming Li, Jianguo Zhang
Sleep disturbances profoundly affect the quality of life in individuals with neurological disorders. Closed-loop deep brain stimulation (DBS) holds promise for alleviating sleep symptoms, however, this technique necessitates automated sleep stage decoding from intracranial signals. We leveraged overnight data from 121 patients with movement disorders (Parkinson's disease, Essential Tremor, Dystonia, Essential Tremor, Huntington's disease, and Tourette's syndrome) in whom synchronized polysomnograms and basal ganglia local field potentials were recorded, to develop a generalized, multi-class, sleep specific decoder - BGOOSE...
May 10, 2024: NPJ Digital Medicine