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https://www.readbyqxmd.com/read/27903364/-a-meta-analysis-of-hiv-seroprevalence-in-pregnant-women-with-syphilis-and-the-impact-of-syphilis-infection-on-mother-to-child-hiv-transmission
#1
T T Wang, Y Xu, Z Z Li, L Z Chen
Objective: To estimate HIV seroprevalence among pregnant women with syphilis and evaluate the influence of syphilis infection on mother-to-child-transmission (MTCT) of HIV by meta-analysis. Methods: We conducted a systematic literature search for 1 678 articles related to maternal syphilis and HIV infection published until October 1(st) 2015 using the PubMed, Web of Science, Chinese Web of Knowledge, Wanfang, Weipu, and SinoMed databases and evaluated the quality of each papers using the STROBE checklist, and the keywords were " pregnant women/maternal/pregnancy" , "syphilis/AIDS" , "HIV/human immunodeficiency virus" , "mother- to-child transimission/vertical transmission" ...
November 6, 2016: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/27902507/smoking-hiv-and-risk-of-pregnancy-loss
#2
Daniel Westreich, Jordan Cates, Mardge Cohen, Kathleen M Weber, Dominika Seidman, Karen Cropsey, Rodney Wright, Joel Milam, Mary A Young, C Christina Mehta, Deborah R Gustafson, Margaret A Fischl, Adaora A Adimora
OBJECTIVE: Cigarette smoking during pregnancy increases risks of poor pregnancy outcomes including miscarriage and stillbirth (pregnancy loss), but the effect of smoking on pregnancy loss among HIV-infected women has not been explored. Here, investigated the impact of smoking on risk of pregnancy loss among HIV-positive and HIV-negative women, and estimated the potential impact of realistic smoking cessation interventions on risk of pregnancy loss among HIV-positive women. DESIGN: We analyzed pregnancy outcomes in HIV-positive and HIV-negative participants in the Women's Interagency HIV Study (WIHS) between 1994 and 2014...
November 29, 2016: AIDS
https://www.readbyqxmd.com/read/27899925/increased-risk-of-group-b-streptococcus-invasive-infection-in-hiv-exposed-but-uninfected-infants-a-review-of-the-evidence-and-possible-mechanisms
#3
REVIEW
Nicolas Dauby, Mustapha Chamekh, Pierrette Melin, Amy L Slogrove, Tessa Goetghebuer
Group B Streptococcus (GBS) is a major cause of neonatal sepsis and mortality worldwide. Studies from both developed and developing countries have shown that HIV-exposed but uninfected (HEU) infants are at increased risk of infectious morbidity, as compared to HIV-unexposed uninfected infants (HUU). A higher susceptibility to GBS infections has been reported in HEU infants, particularly late-onset diseases and more severe manifestations of GBS diseases. We review here the possible explanations for increased susceptibility to GBS infection...
2016: Frontiers in Immunology
https://www.readbyqxmd.com/read/27898593/coinfection-with-hiv-and-hepatitis-c-virus-in-229-children-and-young-adults-living-in-europe
#4
(no author information available yet)
OBJECTIVE: To characterize children, adolescents and young adults infected with HIV/hepatitis C virus (HCV) vertically or before age of 18 years and living in Europe regarding mode of acquisition, HCV genotype, clinical status and treatment. DESIGN: Retrospective, cross-sectional study using pooled data from 11 European paediatric HIV cohorts. METHODS: Patients aged more than 18 months and less than 25 years, with HIV/HCV acquired vertically or in childhood, were included...
January 2, 2017: AIDS
https://www.readbyqxmd.com/read/27898591/tenofovir-exposure-in-utero-and-linear-growth-in-hiv-exposed-uninfected-infants
#5
Stanzi M le Roux, Jennifer Jao, Kirsty Brittain, Tamsin K Phillips, Seun Olatunbosun, Agnes Ronan, Allison Zerbe, Elaine J Abrams, Landon Myer
OBJECTIVE: Tenofovir (TDF) affects bone health and is widely used in pregnancy but data are limited on the effects of TDF exposure in utero. We examined the association between duration of in-utero TDF exposure and linear growth in HIV-exposed, uninfected (HEU) infants. DESIGN: A prospective cohort of pregnant women initiating TDF-containing regimens at primary care services in Cape Town, South Africa, were enrolled and followed with their breastfeeding infants through 12 months postpartum...
January 2, 2017: AIDS
https://www.readbyqxmd.com/read/27898566/antiretroviral-therapy-initiation-is-not-associated-with-risky-sexual-behavior-among-heterosexual-human-immunodeficiency-virus-infected-persons-in-serodiscordant-partnerships
#6
Andrew Mujugira, Connie Celum, Kenneth Ngure, Katherine K Thomas, Elly Katabira, Jared M Baeten
BACKGROUND: Few prospective studies have assessed whether antiretroviral therapy (ART) use is associated with changes in sexual risk behavior of human immunodeficiency virus (HIV)-infected persons in known HIV-serodiscordant partnerships. METHODS: We conducted a longitudinal analysis of HIV-infected persons with known uninfected partners enrolled in the Partners Pre-Exposure Prophylaxis Study in Kenya and Uganda. Antiretroviral therapy use and self-reported sexual behavior were ascertained every 3 months...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27896258/secondary-abdominal-pregnancy-in-human-immunodeficiency-virus-positive-woman
#7
Myoung Chan Kim, Hudson Manyanga, Flora Lwakatare
We report on an abdominal pregnancy in human immunodeficiency virus-positive mother, currently on antiretroviral therapy, which was discovered incidentally while training the obstetric ultrasound capacity building program. Although abdominal pregnancy is a rare form of ectopic pregnancy, it may be more common in women with HIV infection because they tend to have a higher rate of sexually transmitted diseases than the general population. The positive diagnosis of abdominal pregnancy is difficult to establish and is usually missed during prenatal assessment particularly in settings that lack routine ultrasound examination as is the case in most developing countries...
November 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27893488/pregnancy-and-hiv-disease-progression-in-an-early-infection-cohort-from-five-african-countries
#8
Kristin M Wall, Wasima Rida, Lisa Haddad, Anatoli Kamali, Etienne Karita, Shabir Lakhi, William Kilembe, Susan Allen, Mubiana Inambao, Annie H Yang, Mary H Latka, Omu Anzala, Eduard J Sanders, Linda-Gail Bekker, Vinodh A Edward, Matt A Price
BACKGROUND: Understanding associations between pregnancy and HIV disease progression is critical to providing appropriate counseling and care to HIV-positive women. METHODS: From 2006-2011, women under age 40 with incident HIV infection were enrolled in an early HIV infection cohort in Kenya, Rwanda, South Africa, Uganda, and Zambia. Time-dependent Cox models evaluated associations between pregnancy and HIV disease progression. Clinical progression was defined as a single CD4 measurement <200 cells/μL, percent CD4 <14%, or category C event, with censoring at antiretroviral (ART) initiation for reasons other than prevention of mother-to-child transmission (PMTCT)...
November 22, 2016: Epidemiology
https://www.readbyqxmd.com/read/27892820/addressing-adolescents-risk-and-protective-factors-related-to-risky-behaviours-findings-from-a-school-based-peer-education-evaluation-in-the-western-cape
#9
Furzana Timol, Mohammed Yacoob Vawda, Arvin Bhana, Benita Moolman, Mokhantso Makoae, Sharlene Swartz
BACKGROUND: Peer-education programmes aim to bring about attitudinal and behavioural changes in their target audience. In the South African educational context, peer education is a favoured approach in dealing with issues such as HIV and AIDS, sexual decision-making and substance misuse. Given the reliance on peer-education programmes in the educational system, it is important to establish how well they are working. This study aims to assess the effect of an extensive, structured, time-limited, curriculum-based, peer-led educational programme on first-year high school learners in public schools in the Western Cape Province of South Africa...
December 2016: SAHARA J: Journal of Social Aspects of HIV/AIDS Research Alliance
https://www.readbyqxmd.com/read/27887669/couple-interdependence-impacts-hiv-related-health-behaviours-among-pregnant-couples-in-southwestern-kenya-a-qualitative-analysis
#10
Anna Joy Rogers, Lillian Achiro, Elizabeth A Bukusi, Abigail M Hatcher, Zachary Kwena, Pamela L Musoke, Janet M Turan, Elly Weke, Lynae A Darbes
INTRODUCTION: HIV infection is frequently transmitted within stable couple partnerships. In order to prevent HIV acquisition in HIV-negative couples, as well as improve coping in couples with an HIV-positive diagnosis, it has been suggested that interventions be aimed at strengthening couple relationships, in addition to addressing individual behaviours. However, little is known about factors that influence relationships to impact joint decision-making related to HIV. METHODS: We conducted qualitative in-depth interviews with 40 pregnant women and 40 male partners in southwestern Kenya, an area of high HIV prevalence...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/27882759/-management-of-care-of-hiv-positive-pregnant-women-in-the-period-1996-2014
#11
M Mojhová, I Mikysková, M Halaška, M Staňková, H Rozsypal, J Šrámek, J Záhumenský, M Malý
OBJECTIVE: The evaluation of multidisplinary care about HIV positive pregnant women in the Czech Republic. DESIGN: Review. SETTINGS: Gynekologicko-porodnická klinika 1. LF UK a Nemocnice na Bulovce, Praha. METHODS: The vertical transmission of HIV infection from mother to fetus occurs most often during birth, still 1-2% of HIV-positive pregnant women will transfer the virus transplacenta. Due to careful screening for HIV during pregnancy, counselling, combination antiretroviral (cART) therapy, childbirth planning and its performance by C-section there appears a significant decrease of the virus transmission to the fetus, its occurrence is around 2%...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27879980/theory-based-interventions-for-contraception
#12
REVIEW
Laureen M Lopez, Thomas W Grey, Mario Chen, Elizabeth E Tolley, Laurie L Stockton
BACKGROUND: The explicit use of theory in research helps expand the knowledge base. Theories and models have been used extensively in HIV-prevention research and in interventions for preventing sexually transmitted infections (STIs). The health behavior field uses many theories or models of change. However, many educational interventions addressing contraception have no explicit theoretical base. OBJECTIVES: To review randomized controlled trials (RCTs) that tested a theoretical approach to inform contraceptive choice and encourage or improve contraceptive use...
November 23, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27875363/pmtct-option-b-does-not-increase-preterm-birth-risk-and-may-prevent-extreme-prematurity-a-retrospective-cohort-study-in-malawi
#13
Maganizo B Chagomerana, William C Miller, Brian W Pence, Mina C Hosseinipour, Irving F Hoffman, Robert J Flick, Hannock Tweya, Soyapi Mumba, Frank Chibwandira, Kimberly A Powers
OBJECTIVE: To estimate preterm birth risk among infants of HIV-infected women in Lilongwe, Malawi according to maternal antiretroviral therapy (ART) status and initiation time under Option B+. DESIGN: Retrospective cohort study of HIV-infected women delivering at ≥27 weeks of gestation, April 2012-November 2015. Among women on ART at delivery, we restricted our analysis to those who initiated ART before 27 weeks of gestation. METHODS: We defined preterm birth as a singleton live birth at ≥27 and <37 weeks of gestation, with births at <32 weeks classified as extremely to very preterm...
November 21, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27872760/factors-associated-with-pmtct-cascade-completion-in-four-african-countries
#14
Jodie Dionne-Odom, Thomas K Welty, Andrew O Westfall, Benjamin H Chi, Didier Koumavi Ekouevi, Margaret Kasaro, Pius M Tih, Alan T N Tita
Background. Many countries are working to reduce or eliminate mother-to-child transmission (MTCT) of HIV. Prevention efforts have been conceptualized as steps in a cascade but cascade completion rates during and after pregnancy are low. Methods. A cross-sectional survey was performed across 26 communities in Cameroon, Cote d'Ivoire, South Africa, and Zambia. Women who reported a pregnancy within two years were enrolled. Participant responses were used to construct the PMTCT cascade with all of the following steps required for completion: at least one antenatal visit, HIV testing performed, HIV testing result received, initiation of maternal prophylaxis, and initiation of infant prophylaxis...
2016: AIDS Research and Treatment
https://www.readbyqxmd.com/read/27864000/timing-of-initiation-of-antiretroviral-therapy-and-adverse-pregnancy-outcomes-a-systematic-review-and-meta-analysis
#15
Olalekan A Uthman, Jean B Nachega, Jean Anderson, Steve Kanters, Edward J Mills, Françoise Renaud, Shaffiq Essajee, Meg C Doherty, Lynne M Mofenson
BACKGROUND: Although lifelong combination antiretroviral therapy (ART) is recommended for all individuals with HIV, few data exist for pregnancy outcomes associated with ART initiation before conception. We assessed adverse pregnancy outcomes associated with ART initiated before conception compared with that of ART started after conception. METHODS: We did a systematic review of studies from low-income, middle-income, and high-income countries by searching the Cochrane Central Register of Controlled Trials, Embase, LILACS, MEDLINE, Toxline, Web of Knowledge, and WHO Global Index Medicus and trials in progress (International Clinical Trials Registry Platform) for randomised trials, quasi-randomised trials, and prospective cohort studies done between Jan 1, 1980, and June 1, 2016, in which timing of ART initiation in pregnant women living with HIV was reported...
November 15, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27863014/a-multicenter-study-of-diet-quality-on-birth-weight-and-gestational-age-in-infants-of-hiv-infected-women
#16
Tracie L Miller, Denise L Jacobson, Gabriel Somarriba, Daniela Neri, Joy Kurtz-Vraney, Patricia Graham, Matthew W Gillman, David C Landy, Suzanne Siminski, Laurie Butler, Kenneth C Rich, Kristy Hendricks, David A Ludwig
We determined factors associated with diet quality and assessed the relationship between diet quality, birth weight, and gestational age in a prospective national multicenter cohort study. We evaluated diet quality with the Healthy Eating Index (HEI, scale 0-100) in the third trimester of pregnancy with three 24-hr multiple-pass dietary recalls in 266 HIV+ women enrolled in the Pediatric HIV/AIDS Cohort Study. Covariates included demographics, food security, pre-pregnancy body mass index, HIV disease severity, substance use, and antiretroviral exposures...
November 8, 2016: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/27862854/pregnancies-in-older-women-living-with-hiv-in-the-uk-and-ireland
#17
C L Townsend, A de Ruiter, H Peters, C Nelson-Piercy, P Tookey, C Thorne
OBJECTIVES: The aim of the study was to compare maternal characteristics and pregnancy outcomes in women aged < 40 years and ≥ 40 years in a large unselected population of HIV-positive women delivering in the UK and Ireland between 2000 and 2014. METHODS: Comprehensive population-based surveillance data on all HIV-positive pregnant women and their children seen for care in the UK and Ireland are collected through the National Study of HIV in Pregnancy and Childhood...
November 16, 2016: HIV Medicine
https://www.readbyqxmd.com/read/27861487/lifetime-abortion-of-female-sex-workers-in-iran-findings-of-a-national-bio-behavioural-survey-in-2010
#18
Mohammad Karamouzian, Ali Mirzazadeh, Mostafa Shokoohi, Razieh Khajehkazemi, Abbas Sedaghat, Ali Akbar Haghdoost, Hamid Sharifi
INTRODUCTION: Unintended pregnancies and abortion may be considered as occupational hazards for female sex workers (FSWs). As our understanding of contraceptive and abortion practices of Iranian FSWs is very limited, this study tries to assess the dynamics of contraception and abortion among this sub-population. METHODS: This survey was conducted in 2010, by recruiting 872 FSWs through facility-based sampling from 21 sites in 14 cities in Iran. Data were collected through face-to-face interviews using a pilot-tested standardized risk assessment questionnaire...
2016: PloS One
https://www.readbyqxmd.com/read/27842555/low-prevalence-of-laboratory-confirmed-malaria-in-clinically-diagnosed-adult-women-from-the-wakiso-district-of-uganda
#19
Sergey Yegorov, Ronald M Galiwango, Aloysious Ssemaganda, Moses Muwanga, Irene Wesonga, George Miiro, David A Drajole, Kevin C Kain, Noah Kiwanuka, Bernard S Bagaya, Rupert Kaul
BACKGROUND: The malaria burden in sub-Saharan Africa (SSA) has fallen substantially. Nevertheless, malaria remains a serious health concern, and Uganda ranks third in SSA in total malaria burden. Epidemiological studies of adult malaria in Uganda are scarce and little is known about rates of malaria in non-pregnant adult women. This pilot study assessed malaria prevalence among adult women from Wakiso district, historically a highly malaria endemic region. METHODS: Adult women using public health services were screened for malaria, HIV and pregnancy...
November 14, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27836505/a-randomized-clinical-trial-on-the-effects-of-progestin-contraception-in-the-genital-tract-of-hiv-infected-and-uninfected-women-in-lilongwe-malawi-addressing-evolving-research-priorities
#20
Athena P Kourtis, Lisa Haddad, Jennifer Tang, Lameck Chinula, Stacey Hurst, Jeffrey Wiener, Sascha Ellington, Julie A E Nelson, Amanda Corbett, Kristina De Paris, Caroline C King, Mina Hosseinipour, Irving F Hoffman, Denise J Jamieson
Hormonal contraception is central in the prevention of unintended pregnancy; however there are concerns that certain methods may increase the risk of HIV acquisition and transmission. Hormonal contraceptives may modify the genital mucosa in several ways, however the mechanisms are incompletely understood. Few studies have examined genital HIV shedding prospectively before and after initiation of hormonal contraception. The effects of hormonal contraception on genital HIV shedding in the setting of antiretroviral therapy (ART) are also unknown...
November 9, 2016: Contemporary Clinical Trials
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