Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
REVIEW
Irene Sonu, Sun Jung Oh, Satish S C Rao
PURPOSE OF REVIEW: Over the last few decades, there have been remarkable strides in endoscopy and radiological imaging that have advanced gastroenterology. However, the management of neurogastroenterological disorders has lagged behind, in part handicapped by the use of catheter-based manometry that is both non-physiological and uncomfortable. The advent of capsule technology has been a game changer for both diagnostic and therapeutic applications. RECENT FINDINGS: Here, we discuss several capsule devices that are available or under investigation...
April 17, 2024: Current Gastroenterology Reports
#2
JOURNAL ARTICLE
Darren M Brenner, Amol Sharma, Satish S C Rao, Adam P Laitman, Zeev Heimanson, Christopher Allen, Gregory S Sayuk
BACKGROUND: Bloating is a bothersome symptom in irritable bowel syndrome with constipation (IBS-C). AIM: To evaluate plecanatide efficacy in patients with IBS-C stratified by bloating intensity. METHODS: Pooled phase 3 data (2 randomized, controlled IBS-C trials) from adults treated with plecanatide 3 mg or placebo for 12 weeks were analyzed. Patients were stratified post-hoc by baseline bloating severity (11-point scale: mild [≤ 5] and moderate-to-severe [> 5])...
April 9, 2024: Digestive Diseases and Sciences
#3
JOURNAL ARTICLE
Mei Lu, Enrico Speri, A Lauks, Charles Leibson, Satish C Rao
BACKGROUND AND OBJECTIVES: Among health care providers (HCPs), neurologists have one of the highest rates of burnout in the United States, compromising the quality and accessibility of patient care. Patients with refractory epilepsy are especially challenging to treat. This study aims to understand the burnout level in neurologists treating patients with refractory epilepsy and identify key contributing factors. METHODS: US board-certified pediatric/adult neurologists who devote ≥50% of their time to clinical practice and treat ≥10 unique patients with refractory epilepsy annually were invited to take a noninterventional quantitative survey, designed to capture key elements of the HCP's background, burnout level, current practice, burden domains, and satisfaction with current antiseizure medications (ASMs)...
April 2024: Neurology. Clinical Practice
#4
JOURNAL ARTICLE
Satish K Raut, Kulwinder Singh, Shridhar Sanghvi, Veronica Loyo-Celis, Liyah Varghese, Ekam R Singh, Shubha Gururaja Rao, Harpreet Singh
Chloride is a key anion involved in cellular physiology by regulating its homeostasis and rheostatic processes. Changes in cellular Cl- concentration result in differential regulation of cellular functions such as transcription and translation, post-translation modifications, cell cycle and proliferation, cell volume, and pH levels. In intracellular compartments, Cl- modulates the function of lysosomes, mitochondria, endosomes, phagosomes, the nucleus, and the endoplasmic reticulum. In extracellular fluid (ECF), Cl- is present in blood/plasma, and interstitial fluid compartments...
April 4, 2024: Bioscience Reports
#5
JOURNAL ARTICLE
Rizwan Suliankatchi Abdulkader, Manickam Ponnaiah, Tarun Bhatnagar, Devika S, Amanda G A Rozario, Gayathri K, Malu Mohan, Michaelraj E, Divya Saravanakumar, Aditya Moorthy, Amit Kumar Tyagi, Bhagirathsinh D Parmar, K Devaraja, Gaurav Medikeri, Jutika Ojah, Kajal Srivastava, Karthikeyan K, Nandini Das, Niharika B, Parul Sharma, Pradipta Kumar Parida, Prasanna Kumar Saravanam, Praveen Kulkarni, Priya S, Pushpa Patil S, Rahul Kumar Bagla, Ramesh D, Renuka S Melkundi, Satish S Satpute, Seetharaman Narayanan, Shubhashri Jahagirdar, Simmi Dube, Sunil Kumar Panigrahi, Surendra Babu D, Vaibhav Saini, Rita Singh Saxena, Abhinav Srivastava, Achyut Chandra Baishya, Ajai Garg, Amit Kumar Mishra, Anjan Jyoti Talukdar, Ankita Kankaria, Arathi Karat, Arul Sundaresh Kumar, Ashi Chug, Ashok Vankundre, Balakrishnan Ramaswamy, Bharathi Mb, Bhargav R Jadav, Muthuswamy Dhiwakar, Girija Ghate, Hardik V Shah, Ipsita Saha, Kavya Sivapuram, Krupal J Joshi, Mahendra Singh, Mukesh Chand Bairwa, Divya K, Karthikeyan K, Muthurajesh E, Navneh Samagh, Nethra Dinakaran, Nikhil Gupta, Nitin Gupta, Nitin M Nagarkar, Nitin Solanki, Prasan Kumar Panda, Prithvi Bachalli, Raghunath Shanbag, Rajashri Patil, Rajesh Kumar A, Rakesh Narayan Patil, Ramanikanth Thookkanaickenpalayam Vijayaraghavan, Ramesh Hanumantappa, Rathinavel A, Saleel Kumar Mandal, Sanjay Pandharinath Kishve, Sara Varghese Thomas, Saurav Sarkar, Shalini Thakur, Siddaram Patil, Somu Lakshmanan, Srinivas D Rao, Sumathi V, Tulasi Nayak, Umesh R Dixit, Unnikrishnan B, Varsha Backiavathy, Vijendra Shenoy, Vinay Kumar Hallur, Aparna Bhatnagar, Manoj V Murhekar
In India, the incidence of mucormycosis reached high levels during 2021-2022, coinciding with the COVID-19 pandemic. In response to this, we established a multicentric ambispective cohort of patients hospitalised with mucormycosis across India. In this paper, we report their baseline profile, clinical characteristics and outcomes at discharge. Patients hospitalized for mucormycosis during March-July 2021 were included. Mucormycosis was diagnosed based on mycological confirmation on direct microscopy (KOH/Calcofluor white stain), culture, histopathology, or supportive evidence from endoscopy or imaging...
2024: Mycology
#6
JOURNAL ARTICLE
Karthik Nagaraja Rao, Ripu Daman Arora, Anil Sharma, Rupa Mehta, Satish Satpute, Prajwal Dange, Nitin M Nagarkar
Watertight repair of the skull base defect is necessary during endonasal skull base surgery to avoid postoperative CSF leak (poCSFl) and consequent intracranial complications. Various techniques have been described for reconstructing sphenoid-sellar defects with varying success rates. We have described the immediate and long-term outcomes following the reconstruction of sphenoid-sellar defects with our technique. A retrospective analysis of the patients following transsphenoidal sellar surgery underwent barrier restoring reconstruction by multi-layered (inlay-overlay) with autologous thigh fat, fascia lata, fibrin glue, knitted collagen, and absorbable gelatin sponge (modified gasket seal technique)...
March 2024: Indian Journal of Surgical Oncology
#7
REVIEW
Serhat Bor, İsmail H Kalkan, Edoardo Savarino, Satish Rao, Jan Tack, Jay Pasricha, David Cangemi, Jolien Schol, Tennekon Karunaratne, Matteo Ghisa, Nitin K Ahuja, Brian Lacy
BACKGROUND: Prokinetics are a class of pharmacological drugs designed to improve gastrointestinal (GI) motility, either regionally or across the whole gut. Each drug has its merits and drawbacks, and based on current evidence as high-quality studies are limited, we have no clear recommendation on one class or other. However, there remains a large unmet need for both regionally selective and/or globally acting prokinetic drugs that work primarily intraluminally and are safe and without systemic side effects...
March 10, 2024: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
#8
JOURNAL ARTICLE
Tomohito Tsuru, Shu Han, Shutaro Matsuura, Zhenghao Chen, Kyosuke Kishida, Ivan Iobzenko, Satish I Rao, Christopher Woodward, Easo P George, Haruyuki Inui
Refractory high-entropy alloys (RHEAs) are of interest for ultrahigh-temperature applications. To overcome their drawbacks - low-temperature brittleness and poor creep strength at high temperatures - improved fundamental understanding is needed. Using experiments, theory, and modeling, we investigated prototypical body-centered cubic (BCC) RHEAs, TiZrHfNbTa and VNbMoTaW. The former is compressible to 77 K, whereas the latter is not below 298 K. Hexagonal close-packed (HCP) elements in TiZrHfNbTa lower its dislocation core energy, increase lattice distortion, and lower its shear modulus relative to VNbMoTaW whose elements are all BCC...
February 24, 2024: Nature Communications
#9
JOURNAL ARTICLE
Ebby George Simon, Ubal Dhus, Amara Sadguna Rao, Kannan M, Kondala Rao Yedupati, John Titus George, Premkumar K, Anupama Swarna, Aravindh Somasundaram, Arulraj Ramakrishnan, Venkatakrishnan L, Dhanush Thomas, Arulselvan V, Arshiya Mubin S P, Revathy M S, Rakesh Jha, Jeswanth S, Satish Devakumar, Alagammai Pl, Sujata V Gade, Kanagavel Manickavasagam, Deepak Agarwal, Mohan Prasad V G, Madhura Prasad, Mahadevan B, Dinu Abirami, Chandrasekar T S, Gokul B J, Rajesh Natrayan, Harshini Manonmani Sampathkumar, Ramakrishna B S, Naveen Chand, Joseph Jensingh Babu S, Sindhu Ashokan, Arulprakash S, Karishma Srinivasan, Aravind A, Lavanya N, Arun R S, Asher Edward Prem Kumar, Rathnaswami A, Rajesh N A, Arun A C, Ganga Balaji, Padmanabhan P, Somnath Verma, Jayanthi V
BACKGROUND: An increasing incidence of colorectal cancer (CRC) is being reported in developing countries, including India. Most Indian studies on CRC are retrospective and single-centered. The present study is an attempt to understand the current clinical profile and stage of newly diagnosed CRCs across multiple centers in Tamil Nadu, India. METHODS: A multi-centric observational survey was conducted between September 1, 2021, and August 31, 2022, under the aegis of the Indian Society of Gastroenterology - Tamil Nadu chapter...
February 19, 2024: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
#10
JOURNAL ARTICLE
John Valerian Corda, B Satish Shenoy, Kamarul Arifin Ahmad, Leslie Lewis, Prakashini K, Anoop Rao, Mohammad Zuber
Objective: The nasal cavity effectively captures the particles present in inhaled air, thereby preventing harmful and toxic pollutants from reaching the lungs. This filtering ability of the nasal cavity can be effectively utilized for targeted nasal drug delivery applications. This study aims to understand the particle deposition patterns in three age groups: neonate, infant, and adult. Materials and methods: The CT scans are built using MIMICS 21.0, followed by CATIA V6 to generate a patient-specific airway model...
February 11, 2024: Inhalation Toxicology
#11
JOURNAL ARTICLE
Ateev S Chandna, Satish Suhas, Rahul Patley, Damodharan Dinakaran, Narayana Manjunatha, Girish N Rao, Gopalkrishna Gururaj, Mathew Varghese, Vivek Benegal
INTRODUCTION: Post-traumatic stress disorder (PTSD) is a chronic psychiatric condition associated with significant distress and dysfunction. While worldwide estimates of prevalence range from 3.9% to 24%, little research has been conducted to identify the prevalence of PTSD in the general population of India. This study analyzes data from the National Mental Health Survey 2015-2016, a comprehensive epidemiological study of mental health disorders in India, to explore the unique characteristics and prevalence of PTSD in the Indian population...
December 2023: Indian Journal of Psychiatry
#12
JOURNAL ARTICLE
Pavithra Jayasankar, Suhas Satish, Hari Hara Suchandra, Narayana Manjunatha, Girish N Rao, Gopalkrishna Gururaj, Mathew Varghese, Vivek Benegal
INTRODUCTION: Panic disorder (PD) is one of the most common and debilitating anxiety disorder. Individuals with PD seek frequent healthcare and emergency services leading to frequent work absenteeism and economic burden. However, its prevalence patterns in the Indian context are poorly understood. Hence, this article discusses the epidemiology, disability, and treatment gap from India's National Mental Health Survey 2016. MATERIALS AND METHODS: National Mental Health Survey 2016 was a nationally representative epidemiological survey of adult respondents from 12 states of India...
December 2023: Indian Journal of Psychiatry
#13
JOURNAL ARTICLE
Pavithra Jayasankar, Satish Suhas, Lakshmi P Nirisha, Sharad Philip, Narayana Manjunatha, Girish N Rao, Gopalkrishna Gururaj, Mathew Varghese, Vivek Benegal
INTRODUCTION: Generalized anxiety disorder (GAD) is one of the common anxiety disorders leading to impairment and burden. However, GAD remains the least studied anxiety disorder. There is a need for nationally representative epidemiological data of GAD to understand the current burden and plan the mental health policies and programs to attain their unmet needs. Hence, this study focuses on epidemiology, socio-demographic correlates, disability, and treatment gap of GAD from India's National Mental Health Survey (NMHS) 2016...
December 2023: Indian Journal of Psychiatry
#14
JOURNAL ARTICLE
Prakyath Ravindranath Hegde, Lakshmi P Nirisha, Chethan Basavarajappa, Satish Suhas, Channaveerachari Naveen Kumar, Vivek Benegal, Girish N Rao, Mathew Varghese, Gopalkrishna Gururaj
INTRODUCTION: Schizophrenia spectrum disorders represent a significant global health concern, contributing significantly to the global burden of disease. The National Mental Health Survey (NMHS) of India, conducted between 2015 and 2016, investigated the prevalence and epidemiological correlates of schizophrenia spectrum disorders in India. MATERIALS AND METHODS: The NMHS conducted a population-based cross-sectional study in 12 Indian states from 2015 to 2016, encompassing 34,802 adults...
December 2023: Indian Journal of Psychiatry
#15
JOURNAL ARTICLE
Satish Suhas, Narayana Manjunatha, Channaveerachari Naveen Kumar, Vivek Benegal, Girish N Rao, Mathew Varghese, Gopalkrishna Gururaj
The National Mental Health Survey of India (NMHS) was a ground-breaking nationwide study that harnessed a uniform, standardized methodology blending quantitative and qualitative approaches. Covering data from 12 states across diverse regions, its mission was to gauge the prevalence of psychiatric disorders, bridge treatment gaps, explore service utilization, and gauge the socioeconomic repercussions of these conditions. This initiative provided pivotal insights into the intricate landscape of mental health in India...
December 2023: Indian Journal of Psychiatry
#16
JOURNAL ARTICLE
Satish Suhas, Banavaram A Arvind, Gautham M Sukumar, Pradeep S Banandur, Lakshmi P Nirisha, Channaveerachari N Kumar, Vivek Benegal, Girish N Rao, Mathew Varghese, Gopalkrishna Gururaj
BACKGROUND: A staggering 85% of the global population resides in low- and middle-income countries (LAMICs). India stands as an exemplary pioneer in the realm of mental health initiatives among LAMICs, having launched its National Mental Health Program in 1982. It is imperative to effectively evaluate mental health systems periodically to cultivate a dynamic learning model sustained through continuous feedback from mental healthcare structures and processes. MATERIALS AND METHODS: The National Mental Health Survey (NMHS) embarked on the Mental Health Systems Assessment (MHSA) in 12 representative Indian states, following a pilot program that contextually adapted the World Health Organization's Assessment Instrument for Mental Health Systems...
December 2023: Indian Journal of Psychiatry
#17
JOURNAL ARTICLE
Bhavika Vajawat, Satish Suhas, Sydney Moirangthem, Channaveerachari Naveen Kumar, Mathew Varghese, Gopalkrishna Gururaj, Vivek Benegal, Girish N Rao
INTRODUCTION: Bipolar Affective Disorder (BPAD) merits careful consideration within the medical and healthcare communities, researchers, and policymakers. This is due to its substantial disability burden, elevated prevalence of co-morbidities, heightened lifetime risk of suicidality, and a significant treatment gap. This article focuses on the lifetime and current prevalence, correlates, co-morbidities, associated disabilities, socio-economic impact, and treatment gap for BPAD in the adult population of the National Mental Health Survey (NMHS) 2016...
December 2023: Indian Journal of Psychiatry
#18
JOURNAL ARTICLE
Satish Suhas, Pavithra Jayasankar, Rahul Patley, Narayana Manjunatha, Girish N Rao, Gopalkrishna Gururaj, Mathew Varghese, Vivek Benegal
BACKGROUND: Social anxiety disorder (SAD), also termed as social phobia, is a disabling psychiatric condition with limited epidemiological research on it in India. This study, using data from the National Mental Health Survey (NMHS), 2016, is the first to explore its current prevalence and associated factors in India. MATERIALS AND METHODS: The NMHS in India used a comprehensive population-based study with subjects selected through a multistage stratified random cluster sampling technique across 12 states...
December 2023: Indian Journal of Psychiatry
#19
JOURNAL ARTICLE
Jeanetta Frye, Satish Sc Rao
No abstract text is available yet for this article.
January 26, 2024: American Journal of Gastroenterology
#20
JOURNAL ARTICLE
Satish S Rao, Noriaki Manabe, Yusuke Karasawa, Yuko Hasebe, Kazutaka Nozawa, Atsushi Nakajima, Shin Fukudo
OBJECTIVE: To comprehensively evaluate the efficacy, safety, patient symptoms, and quality-of-life (QoL) of lubiprostone, linaclotide, and elobixibat as treatment for chronic constipation (CC). DESIGN: Systematic literature review (SLR) and meta-analysis (MA). Literature searches were conducted on PubMed and Embase using the Ovid platform. METHODS: SLR including randomized controlled trials (RCTs) and observational studies was conducted to identify the overall efficacy and safety of lubiprostone, linaclotide, and elobixibat...
January 2, 2024: BMC Gastroenterology
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
