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https://www.readbyqxmd.com/read/29777044/the-impact-of-sign-glaucoma-guidelines-on-false-positive-referrals-from-community-optometrists-in-central-scotland
#1
Samantha Sii, Ahmad Nasser, Cheng Yi Loo, Catherine Croghan, Alan Rotchford, Pankaj Kumar Agarwal
BACKGROUND: Since the introduction of National Institute for Health and Care Excellence glaucoma guidelines 2009, the number of referrals from community optometrists to hospital eye services has increased across the UK, resulting in increase in first visit discharge rates (FVDRs). AIM: To assess the impact of Scottish Intercollegiate Guidelines Network (SIGN) 144 on quality of referrals from community optometrists. METHODOLOGY: A retrospective study of patient records who attended as new adult glaucoma referrals to clinics in Princess Alexandra Eye Pavilion, Edinburgh, and in Greater Glasgow and Clyde, was carried out across October-November 2014 (group 1) and September-October 2016 (group 2), before and after the introduction of SIGN 144...
May 18, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29776352/surgical-peripheral-iridectomy-via-a-clear-cornea-phacoemulsification-incision-for-pupillary-block-following-cataract-surgery-in-acute-angle-closure
#2
Aiwu Fang, Peijuan Wang, Rui He, Jia Qu
BACKGROUND: To describe a technique of surgical peripheral iridectomy via a clear-cornea tunnel incision to prevent or treat pupillary block following phacoemulsification. METHODS: Description of technique and retrospective description results in 20 eyes of 20 patients with acute angle closure with coexisting visually significant cataract undergoing phacoemulsification considered at risk of postoperative papillary block as well as two pseudo-phakic eyes with acute postoperative pupillary-block...
May 18, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29772496/vibrotactile-feedback-alters-dynamics-of-static-postural-control-in-persons-with-parkinson-s-disease-but-not-older-adults-at-high-fall-risk
#3
Carleigh M High, Hannah F McHugh, Stephen C Mills, Shinichi Amano, Jane E Freund, Srikant Vallabhajosula
BACKGROUND: Aging and Parkinson's disease are often associated with impaired postural control. Providing extrinsic feedback via vibrotactile sensation could supplement intrinsic feedback to maintain postural control. RESEARCH QUESTION: We investigated the postural control response to vibrotactile feedback provided at the trunk during challenging stance conditions in older adults at high fall risk and individuals with Parkinson's disease compared to healthy older adults...
May 8, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29765955/pediatric-multiple-endocrine-neoplasia-type-2b-clinicopathological-correlation-of-perilimbal-mucosal-neuromas-and-treatment-of-secondary-open-angle-glaucoma
#4
Ta Chen Chang, Kingsley C Okafor, Kara M Cavuoto, Sander R Dubovy, Carol L Karp
Ocular findings of multiple endocrine neoplasia type 2B (MEN 2B) include prominent corneal nerves, mucosal neuromas of the conjunctiva, glaucoma, and dry eyes. A 15-year-old girl with MEN 2B presents with advanced secondary open-angle glaucoma and bilateral perilimbal masses. High-resolution optical coherence tomography (HR-OCT) of the perilimbal lesions showed normal epithelial thickness and subepithelial lobular areas of mixed reflectivity, which correlates well with histopathologic findings of benign mucosal neuromas...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29750012/ahmed-glaucoma-valve-in-uveitic-patients-with-fluocinolone-acetonide-implant-induced-glaucoma-3-year-follow-up
#5
Buraa Kubaisi, Arash Maleki, Aseef Ahmed, Neel Lamba, Haitham Sahawneh, Andrew Stephenson, Alyssa Montieth, Shobha Topgi, C Stephen Foster
Purpose: To evaluate the efficacy and safety of Ahmed glaucoma valve (AGV) in eyes with noninfectious uveitis that had fluocinolone acetonide intravitreal implant (Retisert™)-induced glaucoma. Methods: This retrospective study reviewed the safety and efficacy of AGV implantation in patients with persistently elevated intraocular pressure (IOP) after implantation of a fluocinolone acetonide intravitreal implant at the Massachusetts Eye Research and Surgery Institution between August 2006 and November 2015...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29742711/pituitary-apoplexy-following-lumbar-fusion-surgery-in-prone-position-a-case-report
#6
Chunghee Joo, Geol Ha, Yeon Jang
RATIONALE: Pituitary apoplexy (PA) is a syndrome caused by acute hemorrhage or infarction of the pituitary gland, generally within a pituitary adenoma. PA following spinal surgery is a very rare complication and may be difficult to diagnose. However, early diagnosis of PA is essential for the timely treatment of pan-hypopituitarism and prevention of severe neurologic complications. PATIENT CONCERNS: A 73-year-old man had a posterior lumbar fusion surgery over a period of 8 hours on prone position...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29741235/face-cooling-exposes-cardiac-parasympathetic-and-sympathetic-dysfunction-in-recently-concussed-college-athletes
#7
Blair D Johnson, Morgan C O'Leary, Muhamed McBryde, James R Sackett, Zachary J Schlader, John J Leddy
We tested the hypothesis that concussed college athletes (CA) have attenuated parasympathetic and sympathetic responses to face cooling (FC). Eleven symptomatic CA (age: 20 ± 2 years, 5 women) who were within 10 days of concussion diagnosis and 10 healthy controls (HC; age: 24 ± 4 years, 5 women) participated. During FC, a plastic bag filled with ice water (~0°C) was placed on the forehead, eyes, and cheeks for 3 min. Heart rate (ECG) and blood pressure (photoplethysmography) were averaged at baseline and every 60 sec during FC...
May 2018: Physiological Reports
https://www.readbyqxmd.com/read/29739345/atypical-central-retinal-artery-occlusion-as-the-first-presentation-of-poems-syndrome-a-case-report
#8
Panitha Jindahra, Charungthai Dejthevaporn, Pimjai Niparuck, Jariya Waisayarat, Piyaphon Cheecharoen, Thanatporn Threetong, Purit Petpiroon, Tharikarn Sujirakul, Anuchit Poonyathalang, Kavin Vanikieti
BACKGROUND: POEMS syndrome is a plasma cell disorder, which clinically manifests from paraneoplastic syndrome: polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes. The most common ocular manifestation is optic disc swelling, whereas other ocular manifestations; cystoid macular edema, serous macular detachment, venous sinus thrombosis, infiltrative orbitopathy, uveitis, neovascularization of the disc, peripapillary choroidal neovascularization and optic disc drusen, had also been reported...
May 8, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29737605/chronic-high-caloric-diet-modifies-sleep-homeostasis-in-mice
#9
Maria Panagiotou, Johanna H Meijer, Tom Deboer
Obesity prevalence and sleep habit changes are commonplace nowadays, due to modern lifestyle. A bidirectional relationship likely exists between sleep quality and metabolic disruptions, that could impact quality of life. In our study, we investigated the effects of a chronic high-caloric diet on sleep architecture and sleep regulation in mice. We studied the effect of three months high-caloric diet (HCD, 45% fat) on sleep and the sleep electroencephalogram (EEG) in C57BL/6J mice during 24-h baseline (BL) recordings, and after 6-h sleep deprivation (SD)...
May 8, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29726690/human-genome-evolution-and-development-of-cardiovascular-risk-factors-through-natural-selection
#10
R Poledne, J Zicha
Impressive advances in molecular genetic techniques allow to analyze the effects of natural selection on the development of human genome. For example, the trend towards blonde hair and blue eyes was documented. The approach to analyze possible effects of natural selection on the evolution of recent phenotypes with high risk of cardiovascular disease has not been described yet. A possible effect on the evolution of two main risk factors - hypercholesterolemia and hypertension - is presented. The close relationship of non-HDL cholesterol blood concentration to the proportion of pro-inflammatory macrophages in human visceral adipose tissue might be a result of long-lasting natural selection...
May 4, 2018: Physiological Research
https://www.readbyqxmd.com/read/29719642/oct-based-macular-thickness-in-a-normal-indian-pediatric-population
#11
Bharti Nigam, Pragati Garg, Lubna Ahmad, Ritika Mullick
Purpose: Cirrus optical coherence tomography (OCT) provides high resolution cross-sectional images of the retina, vitreous humor, and optic nerve head with an axial resolution of 5 μm and a reproducibility of 1.6 μm. An integrated normative database is available only for adult subjects ≥18 years of age; the normal reference ranges of the macular thicknesses of pediatric subjects are not available. The purpose of this study was to determine the normal reference range of macular thickness of pediatric...
April 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29719424/heart-rate-phenotypes-and-clinical-correlates-in-a-large-cohort-of-adults-without-sleep-apnea
#12
Zhaoyang Huang, Balaji Goparaju, He Chen, Matt T Bianchi
Background: Normal sleep is associated with typical physiological changes in both the central and autonomic nervous systems. In particular, nocturnal blood pressure dipping has emerged as a strong marker of normal sleep physiology, whereas the absence of dipping or reverse dipping has been associated with cardiovascular risk. However, nocturnal blood pressure is not measured commonly in clinical practice. Heart rate (HR) dipping in sleep may be a similar important marker and is measured routinely in at-home and in-laboratory sleep testing...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29715627/why-do-drivers-become-safer-over-the-first-three-months-of-driving-a-longitudinal-qualitative-study
#13
Marianne R Day, Andrew R Thompson, Damian R Poulter, Christopher B Stride, Richard Rowe
Drivers are at high crash risk when they begin independent driving, with liability decreasing steeply over the first three months. Their behavioural development, and other changes underlying improved safety are not well understood. We adopted an innovative longitudinal qualitative design, with thirteen newly qualified drivers completing a total of 36 semi-structured interviews, one, two and three months after acquiring a full UK driving license. The interviews probed high-risk factors for new drivers, as well as allowing space for generating novel road safety issues...
April 28, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29714233/development-of-an-optical-defect-inspection-algorithm-based-on-an-active-contour-model-for-large-steel-roller-surfaces
#14
Jun Yang, Xuekun Li, Jirui Xu, Yuzhong Cao, Yun Zhang, Liping Wang, Sheng Jiang
On-site measurements and defect detection are of great importance for precision ground steel rollers due to their large dimension and weight. In addition to dimensional error, form accuracy, surface roughness, and surface/sub-surface cracks, there also exist optical defect requirements for steel roller surfaces, e.g., speckles, chatter marks, or feed traces. Since rollers with optical defects will always duplicate the defect patterns onto the metal sheet or foil during rolling, it is necessary as well as significant to scrutinize the roller surface after grinding...
April 1, 2018: Applied Optics
https://www.readbyqxmd.com/read/29713141/risk-factors-for-requirement-of-filtration-surgery-after-vitrectomy-in-patients-with-proliferative-diabetic-retinopathy
#15
Masashi Sakamoto, Ryuya Hashimoto, Izumi Yoshida, Takatoshi Maeno
Purpose: We retrospectively reviewed patients with postoperative neovascular glaucoma (NVG) after vitrectomy for proliferative diabetic retinopathy to investigate how variables assessed before, during, and after vitrectomy are associated with the requirement for filtration surgery. Patients and methods: The subjects in this retrospective, observational, comparative study were 55 consecutive patients (61 eyes) who underwent vitrectomy for proliferative diabetic retinopathy at Toho University Sakura Medical Center between December 2011 and November 2016, were followed up for at least 6 months after surgery, and developed NVG within 2 years after surgery...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29709617/exploring-gelatin-nanoparticles-as-novel-nanocarriers-for-timolol-maleate-augmented-in-vivo-efficacy-and-safe-histological-profile
#16
Miral Shokry, Rania M Hathout, Samar Mansour
The use of gelatin has been gaining recognition in ocular delivery for its safety profile and biocompatible properties. Timolol Maleate (TM) is an anti-glaucoma drug possessing poor corneal penetration while causing eye irritation making it an ideal candidate for novel nanoparticulate systems. Timolol maleate loaded Gelatin Nanoparticles (GNPs) were prepared using the double desolvation method utilizing Glutaraldehyde as the crosslinking agent. Optimization of the nanoparticles was achieved through a full-factorial design...
April 27, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29703288/thermal-capsulotomy-initial-clinical-experience-intraoperative-performance-safety-and-early-postoperative-outcomes-of-precision-pulse-capsulotomy-technology
#17
Joobin Hooshmand, Robin G Abell, Penny Allen, Brendan J Vote
PURPOSE: To assess the clinical safety and performance of a new thermal capsulotomy device in patients having cataract surgery. SETTING: Launceston Eye Institute, Launceston, Tasmania, Australia. DESIGN: Prospective case series. METHODS: This single-surgeon consecutive series comprised eyes having capsulotomy with a precision pulse capsulotomy (PPC) device (Zepto). Baseline demographic information and preoperative, intraoperative, and early postoperative outcomes, including complications, intraocular pressure (IOP), flare photometry, corneal and retinal thickness, and specular microscopy were collected and analyzed...
March 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29702978/optic-neuropathy-causing-vertical-unilateral-hemianopsia-after-pars-plana-vitrectomy-for-a-macular-hole-a-case-report
#18
Hirohiko Kawashima, Norihiro Nagai, Hajime Shinoda, Kazuo Tsubota, Yoko Ozawa
INTRODUCTION: Recent progress in medical technology has resulted in improved surgical outcomes of pars plana vitrectomy (PPV); with microincision systems, the incidence of procedure-related complications during surgery has been reduced. However, unpredictable visual field defects after PPV remain an unresolved issue. A few reports have shown that damage to the retinal neurofibers owing to dry-up during air/fluid exchange or retinal neurotoxicity of the dye used to visualize the internal limiting membrane (ILM), as well as unintentional removal of retinal neurofibers during ILM peeling, are responsible for such visual field disorders...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29699984/prevalence-of-glaucoma-in-the-australian-national-eye-health-survey
#19
Stuart Keel, Jing Xie, Joshua Foreman, Pei Ying Lee, Mostafa Alwan, Eamonn T Fahy, Peter van Wijngaarden, Jennifer C Fan Gaskin, Ghee Soon Ang, Jonathan G Crowston, Hugh R Taylor, Mohamed Dirani
AIM: To estimate the prevalence of glaucoma in Australia. METHODS: This was a population-based study of 3098 non-Indigenous Australians (50-98 years) and 1738 Indigenous Australians (40-92 years) stratified by remoteness. Each participant underwent a standard examination that included visual field assessment, tonometry and non-mydriatic fundus photography. Two fellowship-trained glaucoma specialists independently assessed relevant case notes (past ocular history, best-corrected visual acuity, frequency doubling technology visual fields, Van Herick grade, intraocular pressure and optic disc-centred photographs) and assigned a diagnosis ranked on a scale of certainty: none, possible, probable or definite glaucoma...
April 26, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29698452/iridociliary-cysts-do-not-impact-on-posterior-phakic-intraocular-lens-implantation-for-high-myopia-correction-a-prospective-cohort-study-in-1569-eyes
#20
Xi Zhang, Xun Chen, Xiaoying Wang, Xingtao Zhou
PURPOSE: To investigate the clinical characters and effect of iridociliary cysts among patients who had undergone posterior phakic intraocular lens implantation. METHODS: A total 1569 eyes of 866 high myopia patients, who underwent phakic intraocular lens implantation from 1 September 2011 to 31 August 2016, was included in this prospective cohort study. These patients were followed up for more than 12 months postoperatively. RESULTS: During the study period, 218 eyes (14%) of 154 patients were diagnosed with iridociliary cysts by ultrasound biomicroscopy...
2018: PloS One
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