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https://www.readbyqxmd.com/read/28918060/outcomes-of-ahmed-glaucoma-valve-revision-in-pediatric-glaucoma
#1
Ahmed Mansour Al-Omairi, Aliah H Al Ameri, Sami Al-Shahwan, Arif O Khan, Ibrahim Al-Jadaan, Ahmed Mousa, Deepak P Edward
PURPOSE: Encapsulation of the Ahmed glaucoma valve (AGV) plate is a common cause for postoperative elevation of intraocular pressure, especially in children. Many reports have described the outcomes of AGV revision in adults. However, the outcomes of AGV revision in children are poorly documented. The aim of this study was to determine the outcomes of AGV revision in children. DESIGN: Retrospective cross sectional study METHODS: A retrospective chart review of patients less than 15 years of age who underwent AGV revision with a minimum postoperative follow-up of six months was conducted...
September 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28903935/glaucoma-and-intraocular-pressure-in-epic-norfolk-eye-study-cross-sectional-study
#2
Michelle P Y Chan, David C Broadway, Anthony P Khawaja, Jennifer L Y Yip, David F Garway-Heath, Jennifer M Burr, Robert Luben, Shabina Hayat, Nichola Dalzell, Kay-Tee Khaw, Paul J Foster
Objectives To report the distribution of intraocular pressure (IOP) by age and sex and the prevalence of glaucoma.Design Community based cross sectional observational study.Setting EPIC-Norfolk cohort in Norwich and the surrounding rural and urban areas.Participants 8623 participants aged 48-92 recruited from the community who underwent ocular examination to identify glaucoma.Main outcome measures Prevalence and characteristics of glaucoma, distribution of IOP, and the sensitivity and specificity of IOP for case finding for glaucoma...
September 13, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28902332/high-dose-decanted-triamcinolone-for-treatment-resistant-persistent-macular-edema
#3
Ilkay Kilic Muftuoglu, Frank F Tsai, Tiezhu Lin, William R Freeman
BACKGROUND AND OBJECTIVE: To report the outcomes of decanted high-dose intravitreal triamcinolone acetonide (HD-IVTA) injection for treatment-resistant persistent macular edema (ME). PATIENTS AND METHODS: Seventy-seven eyes of 70 consecutive patients who failed prior treatments for persistent ME received as-needed HD-IVTA injections. Best-corrected visual acuity and central macular thickness (CMT) were assessed at all follow-up visits. RESULTS: Thirty-three eyes (42...
September 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28889009/gaze-position-interferes-in-body-sway-in-young-adults
#4
Carolina Menezes Fiorelli, Paula Fávaro Polastri, Sérgio Tosi Rodrigues, André Macari Baptista, Tiago Penedo, Vinicius Alota Ignácio Pereira, Lucas Simieli, Fabio Augusto Barbieri
Postural control is influenced by eye movements. Gaze fixation, which comprises a component of ocular vergence, is important in the acquisition of highly specific task information, but its relation to postural control is little investigated. The aim of the study was to investigate the effects of gaze fixation position(central and lateral fixations) on postural sway in young adults. Forty young adults with ages ranging from 20 to 35 years were invited to participate in the study. Postural sway was measured in quiet stance in bipedal support in three 60-s trials under the following conditions: gaze fixation on a target positioned in front of participant, gaze fixation on a target positioned on right side of participant, and gaze fixation on a target positioned on left side of participant...
September 6, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28887138/-the-role-of-phacoemulsification-in-glaucoma-therapy-a-systematic-review-and-meta-analysis
#5
REVIEW
Marisse Masis, Patrick J Mineault, Eileen Phan, Shan C Lin
Cataract extraction is a safe and effective surgery that has been performed in its modern form for several decades. Many studies have noted that cataract extraction could also have a clinically significant role in the control of co-morbid glaucoma. Lens extraction decreases the pressure within the eye, and intraocular pressure is the only controllable risk factor in glaucoma proven to be effective. A systematic analysis of current evidence is needed to establish strong practice patterns and identify areas where further research is required...
September 5, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28887137/effects-of-a-high-level-of-illumination-before-sleep-at-night-on-chorioretinal-thickness-and-ocular-biometry
#6
Jaemoon Ahn, Soh-Eun Ahn, Kyung-Sook Yang, Seong-Woo Kim, Jaeryung Oh
The choroid is affected by many factors. One of the factors, change in illumination has been suggested to influence choroidal thickness. However, the effects of bright light before sleep at night on the human eye are not well established. The purpose of this study was to investigate the effects of a high level of illumination in the evening on ocular measurements. Twenty-seven men with myopia spent seven consecutive nights in the sleep laboratory. During the first two nights, subjects were exposed to light at 150 lux between 20:00 and midnight...
September 5, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28883787/investigations-into-hypoxia-and-oxidative-stress-at-the-optic-nerve-head-in-a-rat-model-of-glaucoma
#7
Glyn Chidlow, John P M Wood, Robert J Casson
The vascular hypothesis of glaucoma proposes that retinal ganglion cell axons traversing the optic nerve head (ONH) undergo oxygen and nutrient insufficiency as a result of compromised local blood flow, ultimately leading to their degeneration. To date, evidence for the hypothesis is largely circumstantial. Herein, we made use of an induced rat model of glaucoma that features reproducible and widespread axonal transport disruption at the ONH following chronic elevation of intraocular pressure. If vascular insufficiency plays a role in the observed axonal transport failure, there should exist a physical signature at this time point...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28878461/comparison-of-physical-activities-of-female-football-players-in-junior-high-school-and-high-school
#8
Yuri Inoue, Yoshitaka Otani, Seiichi Takemasa
[Purpose] This study aimed to compare physical activities between junior high school and high school female football players in order to explain the factors that predispose to a higher incidence of sports injuries in high school female football players. [Subjects and Methods] Twenty-nine female football players participated. Finger floor distance, the center of pressure during single limb stance with eyes open and closed, the 40-m linear sprint time, hip abduction and extension muscle strength and isokinetic knee flexion and extension peak torque were measured...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28875349/variations-in-optic-nerve-head-morphology-by-intraocular-pressure-in-open-angle-glaucoma
#9
Aaron Wong, Kaliopy Matheos, Zak Prime, Helen V Danesh-Meyer
PURPOSE: To compare optic disc topography in eyes in three intraocular pressure (IOP) groups of <15 mmHg, 15-20 mmHg, and ≥21 mmHg using spectral domain optical coherence tomography (SD-OCT) and confocal scanning laser ophthalmoscopy, adjusting for the degree of damage, as measured by retinal nerve fiber layer (RNFL) thickness and average visual field loss. METHODS: A total of 184 eyes of 112 patients with primary open-angle glaucoma were recruited into groups based on baseline untreated intraocular pressure (IOP) of <15 mmHg (normal-tension glaucoma [NTG], very low), 15-20 mmHg (NTG, medium), or ≥21 mmHg (high-tension glaucoma [HTG])...
September 5, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28868910/-orbital-compartment-syndrome-the-most-frequent-cause-of-blindness-following-facial-trauma
#10
Gusztáv Klenk, József Katona, Gábor Kenderfi, János Lestyán, Katalin Gombos, Andor Hirschberg
INTRODUCTION: Although orbital compartment syndrome is a rare condition, it is still the most common cause of blindness following simple or complicated facial fractures. Its pathomechanism is similar to the compartment syndrome in the limb. Little extra fluid (blood, oedema, brain, foreign body) in a non-space yielding space results with increasingly higher pressures within a short period of time. Unless urgent surgical intervention is performed the blocked circulation of the central retinal artery will result irreversible ophthalmic nerve damage and blindness...
September 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28862933/quality-of-care-of-the-initial-patient-cohort-of-the-diabetes-collaborative-registry-%C3%A2
#11
Suzanne V Arnold, Abhinav Goyal, Silvio E Inzucchi, Darren K McGuire, Fengming Tang, Sanjeev N Mehta, Laurence S Sperling, Thomas M Maddox, Daniel Einhorn, Nathan D Wong, Niklas Hammar, Peter Fenici, Kamlesh Khunti, Carolyn S P Lam, Mikhail Kosiborod
BACKGROUND: Although guidelines and performance measures exist for patients with diabetes mellitus, achievement of these metrics is not well known. The Diabetes Collaborative Registry(®) (DCR) was formed to understand the quality of diabetes mellitus care across the primary and specialty care continuum in the United States. METHODS AND RESULTS: We assessed the frequency of achievement of 7 diabetes mellitus-related quality metrics and variability across the Diabetes Collaborative Registry(®) sites...
August 11, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28862254/one-year-result-of-xen45-implant-for-glaucoma-efficacy-safety-and-postoperative-management
#12
S Z Tan, A Walkden, L Au
PurposeTo report the efficacy, safety profile, and postoperative management of XEN45 implant at 12-month follow-up.Patients and methodsThis was a retrospective, non-randomised interventional case series involving patients who underwent XEN45 implantation by a single, experienced glaucoma specialist in a tertiary centre. Primary outcome measures were the intraocular pressure (IOP) and the number of medications at 1-year follow-up visit. Two IOP criteria were chosen to measure success: IOP ≤21 mm Hg and ≥20% reduction from baseline (criteria one); and IOP ≤15 mm Hg and ≥30% reduction from baseline (criteria two)...
September 1, 2017: Eye
https://www.readbyqxmd.com/read/28858414/association-of-intraocular-pressure-related-factors-and-retinal-vessel-diameter-with-optic-disc-rim-area-in-subjects-with-and-without-primary-open-angle-glaucoma
#13
Qing Zhang, Catherine Jan, Chun Yu Guo, Feng Hua Wang, Yuan Bo Liang, Kai Cao, Zheng Zhang, Di Ya Yang, Ravi Thomas, Ning Li Wang
IMPORTANCE: The data may supports the notion that the mechanical and vascular mechanisms of glaucomatous injury are intertwined BACKGROUND: To study the association of intraocular pressure (IOP) related factors, IOP, trans-lamina cribrosa pressure difference (TLCPD), cerebrospinal fluid pressure (CSFP) and retinal vessel diameters (RVD), central retinal arteriolar equivalent (CRAE), central retinal venular equivalent (CRVE) with neuro-retinal rim area (RA). DESIGN: A population-based, cross-sectional study PARTICIPANTS: 6830 people aged 30 years and over...
August 31, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28853718/genetic-correlations-between-intraocular-pressure-blood-pressure-and-primary-open-angle-glaucoma-a-multi-cohort-analysis
#14
Hugues Aschard, Jae H Kang, Adriana I Iglesias, Pirro Hysi, Jessica N Cooke Bailey, Anthony P Khawaja, R Rand Allingham, Allison Ashley-Koch, Richard K Lee, Sayoko E Moroi, Murray H Brilliant, Gadi Wollstein, Joel S Schuman, John H Fingert, Donald L Budenz, Tony Realini, Terry Gaasterland, William K Scott, Kuldev Singh, Arthur J Sit, Robert P Igo, Yeunjoo E Song, Lisa Hark, Robert Ritch, Douglas J Rhee, Vikas Gulati, Shane Haven, Douglas Vollrath, Donald J Zack, Felipe Medeiros, Robert N Weinreb, Ching-Yu Cheng, Daniel I Chasman, William G Christen, Margaret A Pericak-Vance, Yutao Liu, Peter Kraft, Julia E Richards, Bernard A Rosner, Michael A Hauser, Caroline C W Klaver, Cornelia M vanDuijn, Jonathan Haines, Janey L Wiggs, Louis R Pasquale
Primary open-angle glaucoma (POAG) is the most common chronic optic neuropathy worldwide. Epidemiological studies show a robust positive relation between intraocular pressure (IOP) and POAG and modest positive association between IOP and blood pressure (BP), while the relation between BP and POAG is controversial. The International Glaucoma Genetics Consortium (n=27 558), the International Consortium on Blood Pressure (n=69 395), and the National Eye Institute Glaucoma Human Genetics Collaboration Heritable Overall Operational Database (n=37 333), represent genome-wide data sets for IOP, BP traits and POAG, respectively...
August 30, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28842942/risk-factors-of-age-related-cataract-in-a-chinese-adult-population-the-taizhou-eye-study
#15
Yating Tang, Xiaofeng Wang, Jiucun Wang, Li Jin, Wei Huang, Yi Luo, Yi Lu
IMPORTANCE: Cataract risk factors data will provide epidemic evidence for cataract prevention. BACKGROUND: To study the risk factors for age-related cataract (ARC) in a Chinese adult population. DESIGN: Population-based, cross-sectional study. PARTICIPANTS: 10,234 eligible subjects ≥45 years old (response rate 78.1%). METHODS: We conducted detailed eye examinations including presenting visual acuity (PVA), best-corrected visual acuity (BCVA), slit lamp examination of lens opacities and fundus examination...
August 25, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28816820/factors-that-influence-of-trabectome-surgery-for-glaucoma-patients
#16
Naoki Tojo, Shinya Abe, Atsushi Hayashi
BACKGROUND: The aim of this study was to investigate the factors that influence the outcome of trabectome surgery. METHODS: This was a retrospective nonrandomized study. Seventy-eight glaucoma patients (86 eyes) who underwent trabectome surgeries and were followed up for more than 12 months were included. We classified the subtypes of glaucoma as: primary open-angle glaucoma (23 eyes), pseudo-exfoliation glaucoma (58 eyes), and secondary glaucoma (5 eyes). Forty-seven eyes underwent cataract and trabectome surgeries simultaneously, and 39 underwent only trabectome surgery...
August 14, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28806189/the-use-of-optical-coherence-tomography-in-neuro-ophthalmology
#17
Noel C Y Chan, Carmen K M Chan
PURPOSE OF REVIEW: In the last decade, with the advances of optical coherence tomography (OCT) technology, different imaging protocols and analysis algorithms have been introduced to maximize the potential of this diagnostic tool in the evaluation of different eye diseases. This review aims to provide an update on these additional features, with respect to the management of a diverse range of neuro-ophthalmologic conditions. RECENT FINDINGS: Macular ganglion cell complex (mGCC) analysis has been shown to be superior to peripapillary retinal nerve fiber layer (pRNFL) analysis in certain settings, such as differentiating Leber's hereditary optic neuropathy from functional visual loss; monitoring neurodegenerative diseases or multiple sclerosis; and predicting visual loss in nonarteritic ischemic optic neuropathy...
August 12, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28800574/outcome-of-micropulse-laser-transscleral-cyclophotocoagulation-on-pediatric-versus-adult-glaucoma-patients
#18
Jun Hui Lee, Yuhua Shi, Behzad Amoozgar, Christopher Aderman, Alejandra De Alba Campomanes, Shan Lin, Ying Han
PURPOSE: To study and compare the outcome of micropulse transscelral cyclophotocoagulation in pediatric glaucoma patients to that in adult glaucoma patients. METHODS: Consecutive pediatric and adult patients who received micropulse transscelral cyclophotocoagulation between July 2015 and December 2016 at University of California, San Francisco were retrospectively analyzed. All cases had at least 12-month follow-up. RESULTS: Nine eyes from 9 pediatric patients and 27 eyes from 25 adult patients were included...
August 10, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28795201/downstream-processing-technologies-capturing-and-final-purification-opportunities-for-innovation-change-and-improvement-a-review-of-downstream-processing-developments-in-protein-purification
#19
Nripen Singh, Sibylle Herzer
Increased pressure on upstream processes to maximize productivity has been crowned with great success, although at the cost of shifting the bottleneck to purification. As drivers were economical, focus is on now on debottlenecking downstream processes as the main drivers of high manufacturing cost. Devising a holistically efficient and economical process remains a key challenge. Traditional and emerging protein purification strategies with particular emphasis on methodologies implemented for the production of recombinant proteins of biopharmaceutical importance are reviewed...
August 10, 2017: Advances in Biochemical Engineering/biotechnology
https://www.readbyqxmd.com/read/28791060/outcome-of-single-piece-intraocular-lens-sulcus-implantation-following-posterior-capsular-rupture-during-phacoemulsification
#20
Masomeh Mohebbi, Seyed Ali Bashiri, Seyed Farzad Mohammadi, Behnaz Samet, Fariba Ghassemi, Elham Ashrafi, Fatemeh Bazvand
PURPOSE: To assess the safety and outcome of single-piece posterior chamber intraocular lens (PC-IOL) implantation in the ciliary sulcus following posterior capsular rupture during cataract surgery. METHODS: Patients with posterior capsular rupture during cataract surgery with a single-piece acrylic IOL implanted into the ciliary sulcus were studied. Complete ocular examinations were performed after 6 months postoperatively. RESULTS: Twenty-four eyes were included...
July 2017: Journal of Ophthalmic & Vision Research
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