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https://www.readbyqxmd.com/read/29152242/comparative-assessment-of-canine-origin-lactobacillus-johnsonii-cpn23-and-dairy-origin-lactobacillus-acidophillus-ncdc-15-for-nutrient-digestibility-faecal-fermentative-metabolites-and-selected-gut-health-indices-in-dogs
#1
Sachin Kumar, Ashok K Pattanaik, Shalini Sharma, Reema Gupta, Sunil E Jadhav, Narayan Dutta
The present experiment was undertaken to validate a probiotic of canine origin for its potential use in dogs. A total of fifteen adult female Labrador dogs were allocated to three equal groups and fed a basal diet without probiotic (control) or with probiotic of either canine (Lactobacillus johnsonii CPN23; cPRO) or dairy (L. acidophilus NCDC 15; dPRO) origin for 9 weeks. The digestibility of most macronutrients remained similar among the groups; however, fibre digestibility was improved (P = 0·034) in dogs receiving cPRO...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29152240/nutrient-digestibility-hindgut-metabolites-and-antioxidant-status-of-dogs-supplemented-with-pomegranate-peel-extract
#2
Tony Jose, Ashok K Pattanaik, Sunil E Jadhav, Narayan Dutta, Shalini Sharma
The present study assessed the effect of dietary supplementation of pomegranate peel (methanolic) extract (PPE) on the nutrient digestibility, faecal fermentative metabolites and antioxidant status of dogs. Six medium-sized dogs of mixed breeds were allocated to two groups in a replicated cross-over design and fed a basal diet with and without supplementation of PPE at 50 mg/kg body weight. Each of the experimental periods consisted of 30 d, with a 21 d washout period in between. Results indicated that PPE supplementation led to no significant changes in nutrient digestibility except a trend of improvement (P = 0·070) in crude fibre digestibility...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29141637/molecules-produced-by-probiotics-prevent-enteric-colibacillosis-in-pigs
#3
Ricardo Nordeste, Akalate Tessema, Sapana Sharma, Zlatko Kovač, Chuan Wang, Rocio Morales, Mansel William Griffiths
BACKGROUND: With the advent of antimicrobial resistance in animal pathogens, novel methods to combat infectious diseases are being sought. Among these, probiotics have been proposed as a means of promoting animal health but problems with their use has been reported. Research has demonstrated that bioactive molecules produced during the growth of certain probiotics interfere with bacterial cell-to-cell communication, which consequently results in an attenuation of virulence in a number of pathogens, including E...
November 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29125621/phenolic-composition-and-evaluation-of-the-antimicrobial-activity-of-free-and-bound-phenolic-fractions-from-a-peruvian-purple-corn-zea-mays-l-accession
#4
Lena Gálvez Ranilla, Ashish Christopher, Dipayan Sarkar, Kalidas Shetty, Rosana Chirinos, David Campos
Beneficial effects on overall gut health by phenolic bioactives-rich foods are potentially due to their modulation of probiotic gut bacteria and antimicrobial activity against pathogenic bacteria. Based on this rationale, the effect of the free and bound phenolic fractions from a Peruvian purple corn accession AREQ-084 on probiotic lactic acid bacteria such as Lactobacillus helveticus and Bifidobacterium longum and the gastric cancer-related pathogen Helicobacter pylori was evaluated. The free and bound phenolic composition was also determined by ultra-performance liquid chromatography...
November 10, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29120790/digestion-under-saliva-simulated-gastric-and-small-intestinal-conditions-and-fermentation-in-vitro-by-human-intestinal-microbiota-of-polysaccharides-from-fuzhuan-brick-tea
#5
Guijie Chen, Minhao Xie, Peng Wan, Dan Chen, Hong Ye, Ligen Chen, Xiaoxiong Zeng, Zhonghua Liu
The aim of present study was to examine whether the digestivesystem (saliva, simulated gastric and small intestinal conditions) could break down and large intestinal microbiota could utilize the polysaccharides from Fuzhuan brick tea (FBTPS). The results showed that there was no change in molecular weight, monosaccharide content and content of reducing sugars before and after saliva, simulated gastric and small intestinal digestion, indicating that FBTPS could pass through the digestive system without being broken down and reach the large intestine safely...
April 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29118977/mycotoxin-binder-improves-growth-rate-in-piglets-associated-with-reduction-of-toll-like-receptor-4-and-increase-of-tight-junction-protein-gene-expression-in-gut-mucosa
#6
Linghong Jin, Wei Wang, Jeroen Degroote, Noémie Van Noten, Honglin Yan, Maryam Majdeddin, Mario Van Poucke, Luc Peelman, Anne Goderis, Kurt Van De Mierop, Ronny Mombaerts, Stefaan De Smet, Joris Michiels
Background: Deoxynivalenol (DON) is a mycotoxin produced by Fusarium species in the field, commonly found in cereal grains, which negatively affects performances and health of animals. Mycotoxin binders are supposed to reduce the toxicity of mycotoxins. Method: The effect of a mycotoxin binder (containing acid-activated bentonite, clinoptilolite, yeast cell walls and organic acids) on growth performance and gut health was studied. Hundred and twenty weaning piglets were allocated to 4 treatments, with 5 pens of 6 piglets each, arranged in a 2 × 2 factorial design: control diet; control diet with 1 kg/t binder; control diet with DON; and control diet with DON and 1 kg/t binder...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/29118762/lc3-associated-phagocytosis-is-required-for-dendritic-cell-inflammatory-cytokine-response-to-gut-commensal-yeast-saccharomyces-cerevisiae
#7
Dimitra Lamprinaki, Gemma Beasy, Aleksandra Zhekova, Alexandra Wittmann, Steve James, Jo Dicks, Yoichiro Iwakura, Shinobu Saijo, Xiaomin Wang, Chung-Wai Chow, Ian Roberts, Tamas Korcsmaros, Ulrike Mayer, Thomas Wileman, Norihito Kawasaki
The human fungal microbiota known as mycobiota is increasingly recognized as a critical factor in human gut health and disease. Non-pathogenic commensal yeasts such as Saccharomyces cerevisiae promote homeostasis in the gut, whereas dysbiosis of the gut mycobiota is associated with inflammation. Glycan-binding receptors (lectins) are key host factors in host-mycobiota interaction in the gut. They are expressed on immune cells such as dendritic cells (DCs) and recognize fungal polysaccharides. This interaction is imperative to mount appropriate immune responses for immune homeostasis in the gut as well as clearance of fungal pathogens...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29110118/microrna-in-gastrointestinal-cell-signalling
#8
REVIEW
Priyanka Mishra, Divya Singh, Lilly Ganju, Bhuvnesh Kumar
Our gut forms an important organ and its formation, functioning and homeostasis are maintained by several factors including cell signalling pathways and commensal microflora. These factors affect pathological, physiological and immunological parameters to maintain gut health and prevent its inflammation. Among these, different intracellular signalling pathways play an important role in regulating gut homeostasis. These pathways are in turn regulated by various microRNAs that play a key role in maintaining the balance between tolerance and inflammation...
November 6, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/29104563/promotion-of-early-gut-colonization-by-probiotic-intervention-on-microbiota-diversity-in-pregnant-sows
#9
Katarina Veljović, Miroslav Dinić, Jovanka Lukić, Sanja Mihajlović, Maja Tolinački, Milica Živković, Jelena Begović, Igor Mrvaljević, Nataša Golić, Amarela Terzić-Vidojević
The aim of this work was to design a novel mixed probiotic culture for piglets and to evaluate its beneficial effect on the piglets' gut health. The possible mechanisms of probiotic activity, such as adhesion, competitive pathogen exclusion and influence on gut microbiota diversity were determined. Mixed probiotic starter culture is composed of three thermophilic lactic acid bacteria (LAB) strains: Lactobacillus helveticus BGRA43, Lactobacillus fermentum BGHI14 and Streptococcus thermophilus BGVLJ1-44. The strains BGVLJ1-44 and BGRA43 showed good technological properties (fast milk curdling, strong proteolytic activity)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29103429/immunotherapeutics-in-pediatric-autoimmune-central-nervous-system-disease-agents-and-mechanisms
#10
Margherita Nosadini, Stefano Sartori, Suvasini Sharma, Russell C Dale
Beyond the major advances produced by careful clinical-radiological phenotyping and biomarker development in autoimmune central nervous system disorders, a comprehensive knowledge of the range of available immune therapies and a deeper understanding of their action should benefit therapeutic decision-making. This review discusses the agents used in neuroimmunology and their mechanisms of action. First-line treatments typically include corticosteroids, intravenous immunoglobulin, and plasmapheresis, while for severe disease second-line "induction" agents such as rituximab or cyclophosphamide are used...
August 2017: Seminars in Pediatric Neurology
https://www.readbyqxmd.com/read/29101656/impact-of-enteric-health-and-mucosal-permeability-on-skeletal-health-and-lameness-in-poultry
#11
L R Bielke, B M Hargis, J D Latorre
Intestinal barrier leakage and/or altered gut microbial composition has been shown to markedly impact both osteoblast and osteoclast activities, systemically through circulation of gut immune cells and cytokines and locally by causing inflammation of extraintestinal organs such as the liver and bone marrow. Mild cases of heightened intestinal inflammation can cause bone loss in male mice in the absence of any overt nutritional deficiencies or weight loss, which has also been shown in chickens that have been infected with Salmonella...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29069420/fecal-bacterial-communities-of-wild-captured-and-stranded-green-turtles-chelonia-mydas-on-the-great-barrier-reef
#12
Shamim Shamim, Thomas B Waltzek, Roger Huerlimann, Ellen Ariel
Green turtles ( Chelonia mydas ) are endangered marine herbivores that break down food particles, primarily sea grasses, through microbial fermentation. However, the microbial community and its role in health and disease are still largely unexplored. In this study, we investigated and compared the fecal bacterial communities of eight wild-captured green turtles to four stranded turtles in the central Great Barrier Reef (GBR) regions that include Bowen and Townsville. We used high-throughput sequencing analysis targeting the hypervariable V1- V3 regions of the bacterial 16S rRNA gene...
October 23, 2017: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29056933/linking-the-gut-microbial-ecosystem-with-the-environment-does-gut-health-depend-on-where-we-live
#13
Nishat Tasnim, Nijiati Abulizi, Jason Pither, Miranda M Hart, Deanna L Gibson
Global comparisons reveal a decrease in gut microbiota diversity attributed to Western diets, lifestyle practices such as caesarian section, antibiotic use and formula-feeding of infants, and sanitation of the living environment. While gut microbial diversity is decreasing, the prevalence of chronic inflammatory diseases such as inflammatory bowel disease, diabetes, obesity, allergies and asthma is on the rise in Westernized societies. Since the immune system development is influenced by microbial components, early microbial colonization may be a key factor in determining disease susceptibility patterns later in life...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29053819/changes-in-immune-and-metabolic-gut-response-in-broilers-fed-%C3%AE-mannanase-in-%C3%AE-mannan-containing-diets
#14
R J Arsenault, J T Lee, R Latham, B Carter, M H Kogut
β-galactomannans found in soy-based broiler feed are known to cause physiological effects that are hypothesized to be related to gut inflammation. Previous studies have shown that the incorporation of β-mannanase in the diet or as a supplement results in improvements to certain performance parameters related to gut health and feed conversion. Using kinome analysis, we characterized the mechanism of β-galactomannan activity and supplementation with β-mannanase on the gut of commercial broilers to understand the mode of action...
September 14, 2017: Poultry Science
https://www.readbyqxmd.com/read/29028844/a-polyphenol-enriched-diet-and-ascaris-suum-infection-modulate-mucosal-immune-responses-and-gut-microbiota-composition-in-pigs
#15
Andrew R Williams, Lukasz Krych, Hajar Fauzan Ahmad, Peter Nejsum, Kerstin Skovgaard, Dennis S Nielsen, Stig M Thamsborg
Polyphenols are a class of bioactive plant secondary metabolites that are thought to have beneficial effects on gut health, such as modulation of mucosal immune and inflammatory responses and regulation of parasite burdens. Here, we examined the interactions between a polyphenol-rich diet supplement and infection with the enteric nematode Ascaris suum in pigs. Pigs were fed either a basal diet or the same diet supplemented with grape pomace (GP), an industrial by-product rich in polyphenols such as oligomeric proanthocyanidins...
2017: PloS One
https://www.readbyqxmd.com/read/29028667/impact-of-antiretroviral-drugs-on-the-microbiome-unknown-answers-to-important-questions
#16
Sandra Pinto-Cardoso, Nichole R Klatt, Gustavo Reyes-Terán
PURPOSE OF REVIEW: Little is known on how different antiretroviral (ARV) drugs affect the gut microbiome in HIV infection; and conflicting data exists on the effect of ARV drugs on residual inflammation/immune activation and microbial translocation. RECENT FINDINGS: Gut microbiome involvement in the transmission and pathogenesis of HIV infection is increasingly being recognized. Various studies have shown that antiretroviral therapy (ART) is unable to restore gut health despite effective suppression of plasma HIV viremia...
October 11, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/29022390/randomised-double-blind-placebo-controlled-trial-on-lactobacillus-reuteri-dsm-17938-improvement-in-symptoms-and-bowel-habit-in-functional-constipation
#17
G Riezzo, A Orlando, B D'Attoma, M Linsalata, M Martulli, F Russo
Dysbiosis may contribute to constipation and its symptoms, therefore probiotic administration could improve significantly gut health and functions. The aim of the study was to investigate the effects of a long-lasting administration of Lactobacillus reuteri DSM 17938 (LR DSM 17938) on symptoms and quality of life (QoL) score in patients with functional constipation (FC). 56 FC patients with normal colonic transit time and without anorectal disorders and pelvic floor dysfunctions completed the study. LR DSM 17938 was administered for 105 days in a randomised double-blind clinical trial (28 patients per arm)...
October 12, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28993953/intestinal-toxicity-of-deoxynivalenol-is-limited-by-lactobacillus-rhamnosus-rc007-in-pig-jejunum-explants
#18
Gisela Romina García, Delphine Payros, Philippe Pinton, Cecilia Ana Dogi, Joëlle Laffitte, Manon Neves, María Laura González Pereyra, Lilia Renée Cavaglieri, Isabelle P Oswald
Probiotics have been explored to stimulate gut health in weaned pigs, when they started to consume solid diet where mycotoxins could be present. The aim of this study was to evaluate the effect of Lactobacillus rhamnosus RC007 on the intestinal toxicity of deoxynivalenol (DON) in an ex vivo model. Jejunal explants, obtained from 5-week-old crossbred castrated male piglets, were kept as control, exposed for 3 h to 10 μM DON, incubated for 4 h with 10(9) CFU/mL L. rhamnosus, or pre-incubated 1 h with 10(9) L...
October 9, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28980453/cryopreservation-of-artificial-gut-microbiota-produced-with-in%C3%A2-vitro-fermentation-technology
#19
Lea Bircher, Clarissa Schwab, Annelies Geirnaert, Christophe Lacroix
Interest in faecal microbiota transplantation (FMT) has increased as therapy for intestinal diseases, but safety issues limit its widespread use. Intestinal fermentation technology (IFT) can produce controlled, diverse and metabolically active 'artificial' colonic microbiota as potential alternative to common FMT. However, suitable processing technology to store this artificial microbiota is lacking. In this study, we evaluated the impact of the two cryoprotectives, glycerol (15% v/v) and inulin (5% w/v) alone and in combination, in preserving short-chain fatty acid formation and recovery of major butyrate-producing bacteria in three artificial microbiota during cryopreservation for 3 months at -80°C...
October 4, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/28971068/the-glycolytic-versatility-of-bacteroides-uniformis-cect-7771-and-its-genome-response-to-oligo-and-polysaccharides
#20
Alfonso Benítez-Páez, Eva M Gómez Del Pulgar, Yolanda Sanz
Bacteroides spp. are dominant components of the phylum Bacteroidetes in the gut microbiota and prosper in glycan enriched environments. However, knowledge of the machinery of specific species isolated from humans (like Bacteroides uniformis) contributing to the utilization of dietary and endogenous sources of glycans and their byproducts is limited. We have used the cutting-edge nanopore-based technology to sequence the genome of B. uniformis CECT 7771, a human symbiont with a proven pre-clinical efficacy on metabolic and immune dysfunctions in obesity animal models...
2017: Frontiers in Cellular and Infection Microbiology
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