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Ankle brachial index and coronary artery disease

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https://www.readbyqxmd.com/read/28224925/diabetes-mellitus-is-a-coronary-heart-disease-risk-equivalent-for-peripheral-vascular-disease
#1
Jonathan D Newman, Caron B Rockman, Mikhail Kosiborod, Yu Guo, Hua Zhong, Howard S Weintraub, Arthur Z Schwartzbard, Mark A Adelman, Jeffrey S Berger
Diabetes mellitus (diabetes) is associated with significantly increased risk of peripheral vascular disease. Diabetes is classified as a coronary heart disease (CHD) risk equivalent, but it is unknown whether diabetes is a CHD risk equivalent for peripheral vascular disease. The objective was to evaluate the odds of peripheral arterial disease (PAD) or carotid artery stenosis (CAS) among participants with diabetes, CHD, or both, compared with participants without diabetes or CHD, in a nationwide vascular screening database...
February 2017: American Heart Journal
https://www.readbyqxmd.com/read/28219666/relation-of-iliac-artery-calcium-with-adiposity-measures-and-peripheral-artery-disease
#2
Jane J Lee, Alison Pedley, Ido Weinberg, Kathryn A Britton, Joseph M Massaro, Udo Hoffmann, Emily Manders, Caroline S Fox, Joanne M Murabito
Arterial calcification is associated with cardiovascular morbidity and mortality. To improve the understanding of the pathogenesis involved with iliac artery calcium (IAC), we sought to examine the associations between the burden of IAC with adiposity measures and peripheral artery disease (PAD). Participants (n = 1,236, 52% women, mean age 60 years) were drawn from the Framingham Heart Study Offspring cohort who underwent multidetector computed tomography. The extent of IAC was quantified based on calcified atherosclerotic plaques detected in the iliac arteries...
January 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28160528/meta-analysis-of-individual-patient-data-from-evar-1-dream-over-and-ace-trials-comparing-outcomes-of-endovascular-or-open-repair-for-abdominal-aortic-aneurysm-over-5-years
#3
REVIEW
J T Powell, M J Sweeting, P Ulug, J D Blankensteijn, F A Lederle, J-P Becquemin, R M Greenhalgh
BACKGROUND: The erosion of the early mortality advantage of elective endovascular aneurysm repair (EVAR) compared with open repair of abdominal aortic aneurysm remains without a satisfactory explanation. METHODS: An individual-patient data meta-analysis of four multicentre randomized trials of EVAR versus open repair was conducted to a prespecified analysis plan, reporting on mortality, aneurysm-related mortality and reintervention. RESULTS: The analysis included 2783 patients, with 14 245 person-years of follow-up (median 5·5 years)...
February 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28068560/effect-of-sarpogrelate-a-selective-5-ht2a-receptor-antagonist-on-characteristics-of-coronary-artery-disease-in-patients-with-type-2-diabetes
#4
Dong-Hwa Lee, Eun Ju Chun, Jee Hye Hur, Se Hee Min, Jie-Eun Lee, Tae Jung Oh, Kyoung Min Kim, Hak Chul Jang, Seung Jin Han, Doo Kyoung Kang, Hae Jin Kim, Soo Lim
BACKGROUND AND AIMS: Sarpogrelate, a 5-hydroxytryptamine type 2A antagonist, is a potential antiplatelet agent. We performed a randomized study to evaluate the effect of sarpogrelate on vascular health in Korean patients with diabetes. METHODS: Forty diabetic patients aged 58.6 ± 6.8 years with 10-75% coronary artery stenosis, as assessed by coronary computed tomography angiography, were randomly assigned to sarpogrelate 300 mg/day plus aspirin 100 mg/day (SPG + ASA group) or aspirin 100 mg/day alone (ASA group) for 6 months...
February 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28012644/ankle-brachial-index-and-physical-function-in-older-individuals-the-atherosclerosis-risk-in-communities-aric-study
#5
Kunihiro Matsushita, Shoshana H Ballew, Yingying Sang, Corey Kalbaugh, Laura R Loehr, Alan T Hirsch, Hirofumi Tanaka, Gerardo Heiss, B Gwen Windham, Elizabeth Selvin, Josef Coresh
BACKGROUND AND AIMS: Most prior studies investigating the association of lower extremity peripheral artery disease (PAD) with physical function were small or analyzed selected populations (e.g., patients at vascular clinics or persons with reduced function), leaving particular uncertainty regarding the association in the general community. METHODS: Among 5262 ARIC participants (age 71-90 years during 2011-2013), we assessed the cross-sectional association of ankle-brachial index (ABI) with the Short Physical Performance Battery (SPPB) score (0-12), its individual components (chair stands, standing balance, and gait speed) (0-4 points each), and grip strength after accounting for potential confounders, including a history of coronary disease, stroke, or heart failure...
February 2017: Atherosclerosis
https://www.readbyqxmd.com/read/27993830/secondhand-smoke-exposure-and-subclinical-cardiovascular-disease-the-multi-ethnic-study-of-atherosclerosis
#6
Miranda R Jones, Hoda S Magid, Mahmoud Al-Rifai, John W McEvoy, Joel D Kaufman, Karen D Hinckley Stukovsky, Moyses Szklo, Joseph Polak, Gregory L Burke, Wendy S Post, Michael J Blaha, Ana Navas-Acien
BACKGROUND: Few studies have evaluated the association between secondhand smoke (SHS) and subclinical cardiovascular disease among ethnically diverse populations. This study assesses the impact of SHS on inflammation and atherosclerosis (carotid intima-media thickness, coronary artery calcification, and peripheral arterial disease). METHODS AND RESULTS: We examined 5032 nonsmoking adults aged 45 to 84 years without prior cardiovascular disease participating in the Multi-Ethnic Study of Atherosclerosis (MESA) from 2000 to 2002...
December 19, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27928449/severe-asymptomatic-coronary-obstruction-in-chronic-hemodialysed-patient-a-case-report
#7
C Voiculeț, O Zara, I Văcăroiu, C Bogeanu, T Tiron, F Turcu, G Aron, A Ciocâlteu
Introduction. Arterial stiffness and vascular calcifications are independent predictors of cardiovascular morbidity and mortality in the chronic kidney disease (CKD) stage 5D population. According to the guidelines, patients on renal replacement therapy represent a very high cardiovascular risk class. Case report. We report the case of a 67-year-old hypertensive male patient, known with CKD stage 5D on hemodialysis (three times per week), secondary bone mineral disease, admitted for progressive right leg pain...
October 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27901176/different-methods-of-calculating-ankle-brachial-index-in-mid-elderly-men-and-women-the-brazilian-longitudinal-study-of-adult-health-elsa-brasil
#8
M Miname, I M Bensenor, P A Lotufo
The ankle-brachial index (ABI) is a marker of subclinical atherosclerosis related to health-adverse outcomes. ABI is inexpensive compared to other indexes, such as coronary calcium score and determination of carotid artery intima-media thickness (IMT). Our objective was to identify how the ABI can be applied to primary care. Three different methods of calculating the ABI were compared among 13,921 men and women aged 35 to 74 years who were free of cardiovascular diseases and enrolled in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)...
2016: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/27891375/flow-mediated-dilatation-carotid-intima-media-thickness-ankle-brachial-pressure-index-and-pulse-pressure-in-young-male-post-myocardial-infarction-patients-in-india
#9
Nikhil Gupta, Subhash Giri, Vinita Rathi, Gajender Singh Ranga
INTRODUCTION: Due to increase in Coronary Artery Disease (CAD) at a younger age, we should try to diagnose atherosclerotic process and population at risk, at the earliest. Flow Mediated Dilatation (FMD), Carotid Intima-Media Thickness (CIMT) and Ankle-Brachial Pressure Index (ABI) are probable markers for early atherosclerosis and may be useful in coronary risk stratification. AIM: To compare and correlate the FMD, CIMT, ABI and Pulse Pressure (PP) in young male patients of Myocardial Infarction (MI) with age and sex matched healthy controls...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27865565/-ankle-brachial-index-screening-for-peripheral-artery-disease-in-high-cardiovascular-risk-patients-prospective-observational-study-of-370-asymptomatic-patients-at-high-cardiovascular-risk
#10
C Rada, S Oummou, F Merzouk, B Amarir, G Boussabnia, H Bougrini, D Benzaroual, S Elkarimi, M Elhattaoui
INTRODUCTION: Peripheral arterial disease is a marker of systemic atherosclerosis; it is associated with a high risk of cardiovascular disease. The aim of our study was to assess the prevalence of peripheral arterial disease by measuring the ankle-brachial pressure index in patients at high cardiovascular risk and to study the risk factors associated with this disease. METHODOLOGY: This was a descriptive and analytic cross-sectional study which focused on 370 patients seen at the medical consultation for atherosclerosis prevention...
December 2016: Journal des Maladies Vasculaires
https://www.readbyqxmd.com/read/27861382/single-injection-protocol-for-coronary-and-lower-extremity-ct-angiographies-in-patients-suspected-for-peripheral-arterial-disease
#11
Ashish Khandelwal, Takeshi Kondo, Makoto Amanuma, Akitsugu Oida, Tomonari Sano, Saboo S Sachin, Shinichi Takase, Frank J Rybicki, Kanako K Kumamaru
To evaluate the feasibility of a single injection protocol for coronary CT angiography (CTA) and lower extremity CTA in patients suspected for peripheral arterial disease (PAD).This prospective observational study included a total of 103 patients who showed an ankle brachial index ≤0.9 and underwent the single injection protocol for coronary and lower extremity CTA. All CTAs used iodinated contrast (weight × 0.06 mL/s × 20 seconds). A prospective Electrocardiogram (ECG)-gated coronary CTA was performed, followed by helical lower extremity CTA beginning 9 seconds after coronary CTA...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27741978/peripheral-artery-disease-and-aortic-disease
#12
REVIEW
Michael H Criqui, Victor Aboyans, Matthew A Allison, Julie O Denenberg, Nketi Forbang, Mary M McDermott, Christina L Wassel, Nathan D Wong
We reviewed published MESA (Multi-Ethnic Study of Atherosclerosis) study articles concerning peripheral arterial disease, subclavian stenosis (SS), abdominal aortic calcium (AAC), and thoracic artery calcium (TAC). Important findings include, compared to non-Hispanic whites, lower ankle-brachial index (ABI) and more SS in African Americans, and higher ABI and less SS in Hispanic and Chinese Americans. Abnormal ABI and brachial pressure differences were associated with other subclinical cardiovascular disease (CVD) measures...
September 2016: Global Heart
https://www.readbyqxmd.com/read/27572823/smoking-smoking-cessation-and-measures-of-subclinical-atherosclerosis-in-multiple-vascular-beds-in-japanese-men
#13
Takashi Hisamatsu, Katsuyuki Miura, Hisatomi Arima, Aya Kadota, Sayaka Kadowaki, Sayuki Torii, Sentaro Suzuki, Naoko Miyagawa, Atsushi Sato, Masahiro Yamazoe, Akira Fujiyoshi, Takayoshi Ohkubo, Takashi Yamamoto, Kiyoshi Murata, Robert D Abbott, Akira Sekikawa, Minoru Horie, Hirotsugu Ueshima
BACKGROUND: Smoking is an overwhelming, but preventable, risk factor for cardiovascular diseases (CVD), although smoking prevalence remains high in developed and developing countries in East Asia. METHODS AND RESULTS: In a population-based sample of 1019 Japanese men aged 40 to 79 years, without CVD, we examined cross-sectional associations of smoking status, cumulative pack-years, daily consumption, and time since cessation, with subclinical atherosclerosis at 4 anatomically distinct vascular beds, including coronary artery calcification, carotid intima-media thickness (CIMT) and plaque, aortic artery calcification (AoAC), and ankle-brachial index...
2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27553421/serum-levels-of-mitochondrial-inhibitory-factor-1-are-independently-associated-with-long-term-prognosis-in-coronary-artery-disease-the-genes-study
#14
Annelise Genoux, Laeticia Lichtenstein, Jean Ferrières, Thibaut Duparc, Vanina Bongard, Paul-Louis Vervueren, Guillaume Combes, Dorota Taraszkiewicz, Meyer Elbaz, Michel Galinier, Bertrand Nassar, Jean-Bernard Ruidavets, Bertrand Perret, Laurent O Martinez
BACKGROUND: Epidemiological and observational studies have established that high-density lipoprotein cholesterol (HDL-C) is an independent negative cardiovascular risk factor. However, simple measurement of HDL-C levels is no longer sufficient for cardiovascular risk assessment. Therefore, there is a critical need for novel non-invasive biomarkers that would display prognostic superiority over HDL-C. Cell surface ecto-F1-ATPase contributes to several athero-protective properties of HDL, including reverse cholesterol transport and vascular endothelial protection...
August 23, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27493899/assessment-of-arterial-stiffness-using-the-cardio-ankle-vascular-index
#15
REVIEW
Toru Miyoshi, Hiroshi Ito
BACKGROUND: Arterial stiffness is an independent predictor of outcomes for patients with cardiovascular disease. Although measurement of pulse wave velocity is a widely accepted, noninvasive approach for the assessment of arterial stiffness, its accuracy is affected by changes in blood pressure. SUMMARY: The cardio-ankle vascular index (CAVI) is an index of the overall stiffness of the artery from the origin of the aorta to the ankle and is theoretically independent of blood pressure at the time of measurement...
July 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27492229/imaging-subclinical-atherosclerosis-where-do-we-stand
#16
REVIEW
Nikolaos Papageorgiou, Alexandros Briasoulis, Emmanuel Androulakis, Dimitris Tousoulis
The age of initiation and the rate of progression of atherosclerosis vary markedly among individuals and have been difficult to predict with traditional cardiovascular risk assessment models. Although these risk models provide good discrimination and calibration in certain populations, cardiovascular disease (CVD) risk may not be accurately estimated in low- and intermediate risk individuals. Therefore, imaging techniques such as Ankle-Brachial Index (ABI), Coronary Artery Calcium score (CAC), carotid Intima-Media Thickness (cIMT), flow mediated dilation (FMD) and Positron Emission Tomography (PET) have been developed and used to reclassify these individuals...
2017: Current Cardiology Reviews
https://www.readbyqxmd.com/read/27436826/comparison-of-the-clinical-significance-of-single-cuff-based-arterial-stiffness-parameters-with-that-of-the-commonly-used-parameters
#17
Shunsuke Komatsu, Hirofumi Tomiyama, Kazutaka Kimura, Chisa Matsumoto, Kazuki Shiina, Akira Yamashina
BACKGROUND: We examined the following: (1) whether the new simple markers related to the arterial stiffness/central hemodynamics [i.e. arterial pressure-volume index (API) and arterial velocity pulse index (AVI)] are clinically interchangeable with the commonly used markers [brachial-ankle pulse wave velocity (baPWV) and radial augmentation index (rAI)]; (2) whether the new simple markers reflect vascular damage as reliably as the commonly used markers; (3) which cardiovascular risk factors are reflected by these new simple markers...
July 16, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/27429681/association-of-arterial-pressure-volume-index-with-the-presence-of-significantly-stenosed-coronary-vessels
#18
Takashi Ueda, Shin-Ichiro Miura, Yasunori Suematsu, Yuhei Shiga, Takashi Kuwano, Makoto Sugihara, Amane Ike, Atsushi Iwata, Hiroaki Nishikawa, Kanta Fujimi, Keijiro Saku
BACKGROUND: A blood pressure (BP) monitoring system (PASESA(®)) can be used to easily analyze the characteristics of central and peripheral arteries during the measurement of brachial BP. METHODS: We enrolled 108 consecutive patients (M/F = 86/22, age 70 ± 10 years) who underwent coronary angiography (CAG) due to suspected coronary artery disease (CAD) in whom we could measure various parameters using PASESA(®) in addition to brachial-ankle pulse wave velocity (baPWV)...
August 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27428501/adaptation-of-external-counterpulsation-based-on-individual-shear-rate-therapy-improves-endothelial-function-and-claudication-distance-in-peripheral-artery-disease
#19
Eva-Elina Buschmann, Michele Brix, Lulu Li, Janke Doreen, Andreas Zietzer, Meijing Li, Ivo Buschmann, Philipp Hillmeister
BACKGROUND: External counterpulsation therapy enhances blood flow and was shown to improve endothelial function and quality of life in coronary artery disease patients. However, high pressures of up to 300 mmHg may lead to malperfusion of the ischaemic limb. To improve the clinical outcome of patients with peripheral artery disease (PAD), we adjusted external counterpulsation and developed a novel non-invasive approach termed individual shear rate therapy (ISRT). PATIENTS AND METHODS: In the present study, 14 patients with a Fontaine stage IIb and femoral-popliteal PAD underwent 30 hours of ISRT over 5 weeks...
2016: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/27401737/predictive-value-of-the-augmentation-index-derived-vascular-age-in-patients-with-newly-diagnosed-atherosclerosis
#20
Stefan Betge, Daniel Kretzschmar, Hans-Reiner Figulla, Michael Lichtenauer, Christian Jung
Early detection of atherosclerosis, i.e., in occupational health screening programs could reduce the rate of cardiovascular events in the working population. Changes of the augmentation index (AIX) correlate with changes of the arterial stiffness induced by aging, atherosclerosis, or arterial hypertension and have a prognostic value for cardiovascular events. Their diagnostic yield should be increased by normalizing the AIX to age, in terms of a calculating the vascular age (VA). In this pilot study, 30 patients (mean age 65...
March 2017: Heart and Vessels
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