Read by QxMD icon Read

Ankle brachial index and coronary artery disease

Michael H Criqui, Victor Aboyans, Matthew A Allison, Julie O Denenberg, Nketi Forbang, Mary M McDermott, Christina L Wassel, Nathan D Wong
We reviewed published MESA (Multi-Ethnic Study of Atherosclerosis) study articles concerning peripheral arterial disease, subclavian stenosis (SS), abdominal aortic calcium (AAC), and thoracic artery calcium (TAC). Important findings include, compared to non-Hispanic whites, lower ankle-brachial index (ABI) and more SS in African Americans, and higher ABI and less SS in Hispanic and Chinese Americans. Abnormal ABI and brachial pressure differences were associated with other subclinical cardiovascular disease (CVD) measures...
September 2016: Global Heart
Takashi Hisamatsu, Katsuyuki Miura, Hisatomi Arima, Aya Kadota, Sayaka Kadowaki, Sayuki Torii, Sentaro Suzuki, Naoko Miyagawa, Atsushi Sato, Masahiro Yamazoe, Akira Fujiyoshi, Takayoshi Ohkubo, Takashi Yamamoto, Kiyoshi Murata, Robert D Abbott, Akira Sekikawa, Minoru Horie, Hirotsugu Ueshima
BACKGROUND: Smoking is an overwhelming, but preventable, risk factor for cardiovascular diseases (CVD), although smoking prevalence remains high in developed and developing countries in East Asia. METHODS AND RESULTS: In a population-based sample of 1019 Japanese men aged 40 to 79 years, without CVD, we examined cross-sectional associations of smoking status, cumulative pack-years, daily consumption, and time since cessation, with subclinical atherosclerosis at 4 anatomically distinct vascular beds, including coronary artery calcification, carotid intima-media thickness (CIMT) and plaque, aortic artery calcification (AoAC), and ankle-brachial index...
2016: Journal of the American Heart Association
Annelise Genoux, Laeticia Lichtenstein, Jean Ferrières, Thibaut Duparc, Vanina Bongard, Paul-Louis Vervueren, Guillaume Combes, Dorota Taraszkiewicz, Meyer Elbaz, Michel Galinier, Bertrand Nassar, Jean-Bernard Ruidavets, Bertrand Perret, Laurent O Martinez
BACKGROUND: Epidemiological and observational studies have established that high-density lipoprotein cholesterol (HDL-C) is an independent negative cardiovascular risk factor. However, simple measurement of HDL-C levels is no longer sufficient for cardiovascular risk assessment. Therefore, there is a critical need for novel non-invasive biomarkers that would display prognostic superiority over HDL-C. Cell surface ecto-F1-ATPase contributes to several athero-protective properties of HDL, including reverse cholesterol transport and vascular endothelial protection...
August 23, 2016: BMC Medicine
Toru Miyoshi, Hiroshi Ito
BACKGROUND: Arterial stiffness is an independent predictor of outcomes for patients with cardiovascular disease. Although measurement of pulse wave velocity is a widely accepted, noninvasive approach for the assessment of arterial stiffness, its accuracy is affected by changes in blood pressure. SUMMARY: The cardio-ankle vascular index (CAVI) is an index of the overall stiffness of the artery from the origin of the aorta to the ankle and is theoretically independent of blood pressure at the time of measurement...
July 2016: Pulse (Basel, Switzerland)
Nikolaos Papageorgiou, Alexandros Briasoulis, Emmanuel Androulakis, Dimitris Tousoulis
The age of initiation and the rate of progression of atherosclerosis vary markedly among individuals and have been difficult to predict with traditional cardiovascular risk assessment models. Although these risk models provide good discrimination and calibration in certain populations, cardiovascular disease (CVD) risk may not be accurately estimated in low- and intermediate risk individuals. Therefore, imaging techniques such Ankle-Brachial Index (ABI), Coronary Artery Calcium score (CAC), carotid Intima-Media Thickness (CIMT), flow mediated dilation (FMD) and Positron emission Tomography (PET) have been developed and used to reclassify these individuals...
August 2, 2016: Current Cardiology Reviews
Shunsuke Komatsu, Hirofumi Tomiyama, Kazutaka Kimura, Chisa Matsumoto, Kazuki Shiina, Akira Yamashina
BACKGROUND: We examined the following: (1) whether the new simple markers related to the arterial stiffness/central hemodynamics [i.e. arterial pressure-volume index (API) and arterial velocity pulse index (AVI)] are clinically interchangeable with the commonly used markers [brachial-ankle pulse wave velocity (baPWV) and radial augmentation index (rAI)]; (2) whether the new simple markers reflect vascular damage as reliably as the commonly used markers; (3) which cardiovascular risk factors are reflected by these new simple markers...
July 16, 2016: Journal of Cardiology
Takashi Ueda, Shin-Ichiro Miura, Yasunori Suematsu, Yuhei Shiga, Takashi Kuwano, Makoto Sugihara, Amane Ike, Atsushi Iwata, Hiroaki Nishikawa, Kanta Fujimi, Keijiro Saku
BACKGROUND: A blood pressure (BP) monitoring system (PASESA(®)) can be used to easily analyze the characteristics of central and peripheral arteries during the measurement of brachial BP. METHODS: We enrolled 108 consecutive patients (M/F = 86/22, age 70 ± 10 years) who underwent coronary angiography (CAG) due to suspected coronary artery disease (CAD) in whom we could measure various parameters using PASESA(®) in addition to brachial-ankle pulse wave velocity (baPWV)...
August 2016: Journal of Clinical Medicine Research
Eva-Elina Buschmann, Michele Brix, Lulu Li, Janke Doreen, Andreas Zietzer, Meijing Li, Ivo Buschmann, Philipp Hillmeister
BACKGROUND: External counterpulsation therapy enhances blood flow and was shown to improve endothelial function and quality of life in coronary artery disease patients. However, high pressures of up to 300 mmHg may lead to malperfusion of the ischaemic limb. To improve the clinical outcome of patients with peripheral artery disease (PAD), we adjusted external counterpulsation and developed a novel non-invasive approach termed individual shear rate therapy (ISRT). PATIENTS AND METHODS: In the present study, 14 patients with a Fontaine stage IIb and femoral-popliteal PAD underwent 30 hours of ISRT over 5 weeks...
2016: VASA. Zeitschrift Für Gefässkrankheiten
Stefan Betge, Daniel Kretzschmar, Hans-Reiner Figulla, Michael Lichtenauer, Christian Jung
Early detection of atherosclerosis, i.e., in occupational health screening programs could reduce the rate of cardiovascular events in the working population. Changes of the augmentation index (AIX) correlate with changes of the arterial stiffness induced by aging, atherosclerosis, or arterial hypertension and have a prognostic value for cardiovascular events. Their diagnostic yield should be increased by normalizing the AIX to age, in terms of a calculating the vascular age (VA). In this pilot study, 30 patients (mean age 65...
July 11, 2016: Heart and Vessels
Chiara Mozzini, Alder Casadei, Giuseppe Roscia, Luciano Cominacini
BACKGROUND: Cigarette smoking is known as a major risk factor in the pathogenic mechanisms of stroke, coronary and peripheral artery disease (CAD and PAD), even in young subjects. The aim of this study is the creation of a four-step ultrasound examination to evaluate and monitor the peripheral, the extra and the intra-cranial assessment of the arterial early damage in smokers. The evaluations of A, the Ankle-brachial index, ABI, B, the Breath holding index, BHI, C, the Carotid intima media thickness, CIMT, and D, the Diameter of the abdominal aorta represent the "ABCD" assessment...
2016: BMC Cardiovascular Disorders
Baoze Qu, Qifeng Liu, Jinzhao Li
The ankle-brachial index (ABI) is the ratio of the ankle versus brachial systolic blood pressure. ABI of <0.90 indicates the presence of peripheral arterial disease. Some studies indicated that ABI may correlate with the all-cause mortality. The aim of this study was to assess the prognostic significance of ABI of <0.90 as such predictor of all-cause mortality. In addition, we wished to test the association between ABI and cardiovascular or non-cardiovascular mortality. To this end, we carried out a systematic review of the studies published in MEDLINE that reported both ABI and all-cause mortality...
November 2015: Cell Biochemistry and Biophysics
Toshiki Kawamiya, Susumu Suzuki, Hideki Ishii, Kenshi Hirayama, Kazuhiro Harada, Yohei Shibata, Yosuke Tatami, Shingo Harata, Kazuhiro Kawashima, Ayako Kunimura, Yohei Takayama, Yusaku Shimbo, Naohiro Osugi, Dai Yamamoto, Tomoyuki Ota, Chikao Kono, Toyoaki Murohara
AIM: Malnutrition is associated with the development of atherosclerosis and an increased risk of cardiovascular mortality in elderly patients. The present study aimed to investigate the association between the Geriatric Nutritional Risk Index (GNRI), a simple nutritional assessment tool, and the prevalence of peripheral artery disease (PAD) in elderly coronary artery disease patients. METHODS: We evaluated 228 elderly coronary artery disease patients (mean age 74...
June 15, 2016: Geriatrics & Gerontology International
Jeffrey S Berger, Brian G Katona, W Schuyler Jones, Manesh R Patel, Lars Norgren, Iris Baumgartner, Juuso Blomster, Kenneth W Mahaffey, Peter Held, Marcus Millegård, Gretchen Heizer, Craig Reist, F Gerry Fowkes, William R Hiatt
BACKGROUND: Despite overwhelming data demonstrating the efficacy of antiplatelet therapy in heart disease and stroke, data in peripheral artery disease (PAD) are less compelling. Aspirin has modest evidence supporting a reduction in cardiovascular events in patients with PAD, whereas clopidogrel monotherapy may be more effective in PAD. Ticagrelor, a potent, reversibly binding P2Y12 receptor antagonist, is beneficial in patients with acute coronary syndrome and prior myocardial infarction...
May 2016: American Heart Journal
David I Feldman, Miguel Cainzos-Achirica, Kevin L Billups, Andrew P DeFilippis, Kanchan Chitaley, Philip Greenland, James H Stein, Matthew J Budoff, Zeina Dardari, Martin Miner, Roger S Blumenthal, Khurram Nasir, Michael J Blaha
BACKGROUND: The association between subclinical cardiovascular disease and subsequent development of erectile dysfunction (ED) remains poorly described. HYPOTHESIS: Among multiple subclinical atherosclerosis and vascular dysfunction measurements, coronary artery calcium (CAC) score best predicts ED. METHODS: After excluding participants taking ED medications at baseline, we studied 1862 men age 45 to 84 years free of known cardiovascular disease from the Multi-Ethnic Study of Atherosclerosis (MESA) with comprehensive baseline subclinical vascular disease phenotyping and ED status assessed at MESA visit 5 (9...
May 2016: Clinical Cardiology
Li-Hsin Chang, Chii-Min Hwu, Chia-Huei Chu, Justin G S Won, Ching-Fai Kwok, Hong-Da Lin, Harn-Shen Chen, Yi-Chun Lin, Liang-Yu Lin
OBJECTIVE: The association between ankle brachial index (ABI) and outcomes in diabetic subjects is controversial. The purpose of this study was to evaluate whether the ABI is more strongly associated with cardiovascular outcomes comparing with non-high-density lipoprotein cholesterol (non-HDL-c). RESEARCH DESIGN AND METHODS: A total of 452 type 2 diabetic subjects followed up for a mean of 5.8 years were grouped by ABI (<0.9 versus ≥0.9) and non-HDL-c (<100mg/dL versus ≥100mg/dL)...
May 2016: American Journal of the Medical Sciences
Gabriele Cioni, Rossella Marcucci, Anna Maria Gori, Serafina Valente, Cristina Giglioli, Gian Franco Gensini, Rosanna Abbate, Maria Boddi
BACKGROUND: Strong evidence supports an association between high levels of homocysteine (Hcy) and lipoprotein(a) [Lp(a)] and an increased rate of ischemic vascular events. METHODS: The study population comprised 162 patients (50 women [30.9%]; age, 66.71 ± 12.76 years) having a history of acute coronary syndrome within 1 year who underwent fasting blood sampling, measurement of intima-media thickness and pulse wave velocity at the common carotid and femoral arteries by Doppler ultrasound, and ankle-brachial index measurement...
July 2016: Journal of Vascular Surgery
Chi-Lun Huang, Yuh-Shiun Jong, Yen-Wen Wu, Wei-Jie Wang, Ai-Ru Hsieh, Chia-Lun Chao, Wen-Jone Chen, Wei-Shiung Yang
BACKGROUND: Thrombospondin-1 (TSP-1) is known to be involved in the regulation of angiogenesis, inflammation, and vascular function. Clinical studies have demonstrated its correlation with peripheral artery disease, coronary artery disease, and pulmonary hypertension. In this study, we explored its potential roles in the background of end-stage renal disease (ESRD). METHODS: A total of 140 ESRD outpatients (ages 61.0 ± 12.4 years) were prospectively followed for 34 ± 7 months...
March 2015: Acta Cardiol Sin
Nagwa A Lachine, Abdel Aziz Elnekiedy, Magdy Helmy Megallaa, Gihane I Khalil, Mohamed A Sadaka, Kamel H Rohoma, Heba S Kassab
CONTEXT: Chemerin is one of the adipokines that regulate fat metabolism. High-sensitivity C-reactive protein (hs-CRP) may be considered as a cardiovascular risk predictor. Measuring intima-media thickness of the CCA (C-IMT) is a well-evidenced tool for the detection of early stages of atherosclerosis. We aimed here to study both serum chemerin and hs-CRP as markers of subclinical atherosclerosis in Egyptian patients with type 2 diabetes, who are angiographically free of coronary artery disease (CAD)...
April 2016: Therapeutic Advances in Endocrinology and Metabolism
Lewis H Kuller, Oscar L Lopez, Rachel H Mackey, Caterina Rosano, Daniel Edmundowicz, James T Becker, Anne B Newman
BACKGROUND: The successful prevention and treatment of coronary heart disease (CHD) and stroke has resulted in a substantial increase in longevity, with subsequent growth in the population of older people at risk for dementia. OBJECTIVES: The authors evaluated the relationship of coronary and other peripheral atherosclerosis to risk of death, dementia, and CHD in the very elderly. Because the extent of vascular disease differs substantially between men and women, sex- and race-specific analyses were included, with a specific focus on women with low coronary artery calcium (CAC) Agatston scores...
March 8, 2016: Journal of the American College of Cardiology
S Rico Martín, J M de Nicolás Jiménez, S L Moyano Calvente, M V Mogollón Jiménez, J Vega Fernández, J F Calderón García, M A Bacaicoa Lopez de Sabando, M Tardio, J F Sánchez Muñoz-Torrero
OBJECTIVE: The pulse wave velocity (PWV) in the great arteries is an indicator of vascular risk. Our objective was to identify the PWV index between the arms and legs that best correlates with the coronary calcium quantification (CCQ) and to compare it with other methods. MATERIAL AND METHODS: Eight-one patients without vascular disease underwent the following measurements: CCQ; carotid intima-media thickness (IMT); carotid-femoral PWV (cfPWV), using COMPLIOR; and PWV in the arms and legs, with our own device (abiPWV, ankle brachial index PWV)...
May 2016: Revista Clínica Española
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"