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spray cryotherapy

Kelly J Janke, Abbas El-Sayed Abbas, Vishnu Ambur, Daohai Yu
OBJECTIVE: Spray cryotherapy (SCT), the application of liquid nitrogen in a noncontact form, has been demonstrated to have efficacy in treating various types of pathologic lesions of the airway when used as an adjunct with bronchoscopy. The purpose of the study was to evaluate the results of the use of bronchoscopic SCT on the airway in a single institution. METHODS: We performed a retrospective review of data collected on all patients who underwent SCT to re-establish or improve airway patency in an 11-month period...
September 23, 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
Faiz Y Bhora, Adil Ayub, Craig M Forleiter, Chyun-Yin Huang, Khalid Alshehri, Sadiq Rehmani, Adnan M Al-Ayoubi, Wissam Raad, Robert S Lebovics
Importance: Tracheal stenosis is a debilitating disorder with heterogeneity in terms of disease characteristics and management. Repeated recurrences substantially alter patients' quality of life. There is limited evidence for the use of spray cryotherapy (SCT) in the management of benign airway disease. Objective: To report our early results for the use of SCT in patients with benign tracheal stenosis. Design, Setting, and Participants: Data were extracted from the medical records of a consecutive series of patients with benign airway stenosis secondary to granulomatosis with polyangiitis (GPA) (n = 13), prior tracheotomy or tracheal intubation (n = 8), and idiopathic strictures (n = 5) treated from September 1, 2013, to September 30, 2015, at a tertiary care hospital...
August 11, 2016: JAMA Otolaryngology—Head & Neck Surgery
Li-Juan Yang, Dong-Ning Zhu, Yan-Ling Dang, Xiong Zhao
Patients with condyloma acuminata (CA) during pregnancy represent a special risk group. The outcomes of many treatment methods for such cases are not satisfactory. The purpose of the present study was to evaluate the treatment outcome and safety of cryotherapy combined with proanthocyanidins (PCs) for CA in pregnant women. In this study, 46 pregnant women with CA were treated with cryotherapy combined with PCs. The lesions were sprayed with liquid nitrogen until the color of the wart changed from flesh colored to purple...
June 2016: Experimental and Therapeutic Medicine
David M DiBardino, Anthony R Lanfranco, Andrew R Haas
Cryotherapy is an evolving therapeutic and diagnostic tool used during bronchoscopy. Through rapid freeze-thaw cycles, cryotherapy causes cell death and tissue necrosis or tissue adherence that can be used via the flexible or rigid bronchoscope. This extreme cold can be used through the working channel of the bronchoscope via a specialized cryoprobe or directly with the use of spray cryotherapy. These properties allow for multiple bronchoscopic techniques, each with its own equipment and procedural, safety, and efficacy considerations...
August 2016: Annals of the American Thoracic Society
Ahmet Yılmaz, Erol Çenesizoğlu
OBJECTIVE: The aim of this study was to investigate the effectiveness of cryotherapy applied for the purpose of matricectomy following partial nail removal in treatment of ingrown nails. METHODS: Between 2010 and 2013, 76 ingrown toenails of 62 patients were included in this prospective study. Following partial toenail removal, matricectomy with cryotherapy was performed. The lateral nail matrix was frozen for 45 seconds with open spray and spot-freezing technique using liquid nitrogen...
2016: Acta Orthopaedica et Traumatologica Turcica
Vijay P Zawar, Gayatri Mukund Karad
CONTEXT: Recalcitrant alopecia areata (AA) is not uncommon in clinical practice. In certain patients, treatment failures are known with almost every conventional therapy either singly or in combination. AIMS: To study the efficacy of liquid nitrogen (LN) cryotherapy in patients with recalcitrant AA. SUBJECTS AND METHODS: We present series of eleven patients of recalcitrant AA, who consulted us after getting no response to various modalities of treatment for 6 months...
January 2016: International Journal of Trichology
Uday Chowdary Birapu, Ravindar Puppala, Balaji Kethineni, Sunitha Banavath
Mucocoeles are commonly observed lesions in children and young adults. Conventional management using a scalpel aims at enucleation, requiring psychological preparation of the parent as well as the child because of inherent fear and apprehension towards surgery. This is still more complex in children with visual impairment. The other management techniques are laser, cryotherapy and micromarsupialisation, management strategies that, being painless and tolerable, reduce the anxiety of the child and are therefore more acceptable...
2016: BMJ Case Reports
Robert Browning, J Francis Turner, Scott Parrish
BACKGROUND: Spray cryotherapy (SCT) was initially developed for gastroenterology (GI) endoscopic use in the esophagus. In some institutions where a device has been utilized by GI, transition to use in the airways by pulmonologists and thoracic surgeons occurred. Significant differences exist, however, in the techniques for safely using SCT in the airways. METHODS: We describe the early experience at Walter Reed National Military Medical Center from 2011 to 2013 using SCT in patients with malignant airway disease and the evolution of our current techniques and clinical practice patterns for SCT use in patients...
December 2015: Journal of Thoracic Disease
Basma Mourad, Nashwa Elfar, Shimaa Elsheikh
BACKGROUND: Keloids may follow local skin trauma or inflammation leading to pruritus, pain, restriction of movement or cosmetic disfigurement. OBJECTIVES: To compare between the efficacy and tolerability of spray versus intralesional cryotherapy for keloids. PATIENTS AND METHODS: Fifty patients with keloids were randomized to treatment with spray cryotherapy (group I) or intralesional cryotherapy (group II). Swada and Sone scoring of scars was performed at treatment and follow-up (6 months)...
2016: Journal of Dermatological Treatment
Jared Martínez-Coronado, Bertha Torres-Álvarez, Juan Pablo Castanedo-Cázares
Cryosurgery is a common therapeutic modality used in dermatology; therefore we must be aware of its possible adverse effects. We report a case of a patient with subcutaneous emphysema which occurred following the application of cryotherapy after multiple punctures of local anesthetic and intralesional steroids in a chest keloid scar. Despite the fact that this condition was gradually resolved after expectant observation, we warn about this complication when sprayed cryotherapy is preceded by multiple punctures on cutaneous lesions above bony surfaces...
2015: Case Reports in Dermatological Medicine
F Collado-Mesa, J M Net, K Arheart, G A Klevos, M M Yepes
AIM: To assess whether the application of a topical vapocoolant spray immediately prior to initial intradermal anaesthetic injection during ultrasound-guided breast biopsy decreases pain at the site of the initial injection. MATERIALS AND METHODS: In this institutional review board-approved, Health Insurance Portability and Accountability Act (HIPAA)-compliant study, 50 women aged 49.1 ± 1.6 years (mean ± standard error) were recruited and provided written informed consent...
September 2015: Clinical Radiology
Dennis Yang, Mary K Reinhard, Mihir S Wagh
AIM: To assess the feasibility and safety of liquid nitrogen spray cryoablation at the duodenal papilla in a porcine model. METHODS: This prospective study protocol was approved by the University of Florida Institutional Animal Care and Use Committee. Six pigs underwent liquid nitrogen spray cryotherapy at the duodenal papilla. Freeze time of 20-s was applied per cycle (4 cycles/session). Survival animals (n = 4) were monitored for adverse events. Hemoglobin, white blood count, liver tests, and lipase were obtained at baseline and post-treatment...
June 25, 2015: World Journal of Gastrointestinal Endoscopy
Babak Shadgan, Sports Med, Amir H Pakravan, Alison Hoens, W Darlene Reid
CONTEXT: Vapocoolant spray, commonly known as cold spray (CS), is a cryotherapy modality used in sports medicine, athletic training, and rehabilitation settings. Proposed physiologic effects of cryotherapy modalities include reductions in tissue blood flow, oxygenation, and cell metabolism in addition to attenuation of pain perception attributed to reduced superficial nerve conduction velocity. OBJECTIVE: To examine the effects of CS on subcutaneous and intramuscular blood flow and oxygenation on the thigh muscle using near-infrared spectroscopy, an optical method to monitor changes in tissue oxygenated (O2Hb), deoxygenated (HHb), and total (tHb) hemoglobin...
August 2015: Journal of Athletic Training
Javier Labandeira, Igor Vázquez-Osorio, Olalla Figueroa-Silva, Manuel Pereiro, Jaime Toribio
Xanthelasma are cholesterol-filled, soft, yellow plaques that usually appear on the medial aspects of the eyelids bilaterally. They are always benign lesions so therapy is usually undertaken only for cosmetic reasons. Surgical excision, chemical peeling with tricholoroacetic acid, and laser ablation are commonly used treatments. Liquid nitrogen cryotherapy is a potentially effective but rarely used treatment due to the risk of intense eyelid swelling. We report on our experience with four of our patients, and propose an explanation for the effectiveness of gentle liquid nitrogen spray cryotherapy in xanthelasma...
November 2015: Dermatologic Therapy
C Huber, J Swanenburg, M Leusch, P M Tscholl
BACKGROUND: The application of ice or other forms of cooling represent a common method to treat acute musculoskeletal injuries during sporting events in order to reduce pain. Often athletes return to competition immediately after cooling. It is not known if short-term cryotherapy in the form of ice spray has an influence on the joint's dynamic stability. The aim of this study was to investigate if application of ice spray to the ankle has an effect on the dynamic stability of the joint in healthy participants...
June 2015: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
Silviu Albu, Veronica Trombitas, Diana Vlad, Enzo Emanuelli
OBJECTIVES/HYPOTHESIS: The aim of this study was to assess the influence of spray cryotherapy on wound healing following endoscopic sinus surgery (ESS). STUDY DESIGN: A prospective, randomized, double-blinded, controlled trial. METHODS: The study included 22 consecutive adult patients with chronic rhinosinusitis with and without polyps scheduled for bilateral ESS. At the end of the surgical procedure, patients were randomized to the distribution of spray cryotherapy in one middle meatus and saline contralaterally...
January 2016: Laryngoscope
S Ghorbani, F C Tsai, B D Greenwald, S Jang, J A Dumot, M J McKinley, N J Shaheen, F Habr, W J Coyle
Retrospective series have shown the efficacy of endoscopic spray cryotherapy in eradicating high-grade dysplasia (HGD) in Barrett's esophagus (BE); however, prospective data are lacking, and efficacy for low-grade dysplasia (LGD) is unclear. The aim of this study was to assess the efficacy and safety of spray cryotherapy in patients with LGD or HGD. A multicenter, prospective open-label registry enrolled patients with dysplastic BE. Spray cryotherapy was performed every 2-3 months until there was no endoscopic evidence of BE and no histological evidence of dysplasia, followed by surveillance endoscopies up to 2 years...
April 2016: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
Felician Chirteş, Veronica Trombitas, Diana Vlad, Flaviu Tabaran, Cristian Berce, Silviu Albu
Myringotomy and ventilation tube placement is an office-based procedure and represents the treatment of choice for middle ear effusions and for transtympanic drug administration. The aim of our study was to study the efficiency of low-pressure spray cryotherapy on protraction of patency time of myringotomies in rats. Bilateral myringotomies were performed with cold instruments. Afterward, one ear in each rat was randomly assigned for liquid nitrogen treatment of the perforated eardrum. Myringotomy patency was recorded daily and histological analysis of the eardrums was performed...
March 2015: Indian Journal of Otolaryngology and Head and Neck Surgery
Edward C Kuan, Ashley A Hamamoto, Victor Sun, Tony Nguyen, Cyrus T Manuel, Dmitry E Protsenko, Brian J F Wong, J Stuart Nelson, Wangcun Jia
BACKGROUND/OBJECTIVES: Similar to conventional cryogen spray cooling, carbon dioxide (CO2) spray may be used in combination with laser cartilage reshaping (LCR) to produce cartilage shape change while minimizing cutaneous thermal injury. Recent ex vivo evaluation of LCR with CO2 cooling in a rabbit model has identified a promising initial parameter space for in vivo safety and efficacy evaluation. This pilot study aimed to evaluate shape change and cutaneous injury following LCR with CO2 cooling in 5 live rabbits...
December 2014: Lasers in Surgery and Medicine
Louis M Wong Kee Song, Michael J Levy
Several new devices and innovative adaptations of existing modalities have emerged as primary, adjunctive, or rescue therapy in endoscopic hemostasis of gastrointestinal hemorrhage. These techniques include over-the-scope clip devices, hemostatic sprays, cryotherapy, radiofrequency ablation, endoscopic suturing, and endoscopic ultrasound-guided angiotherapy. This review highlights the technical aspects and clinical applications of these devices in the context of nonvariceal upper gastrointestinal bleeding.
December 2014: Gastroenterology Clinics of North America
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