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https://www.readbyqxmd.com/read/28927839/a-novel-method-to-prevent-catheter-dysfunction-during-spray-cryotherapy
#1
Kavel Visrodia, Liam Zakko, Theresa Nolte, Kenneth K Wang
No abstract text is available yet for this article.
September 16, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28881903/safety-and-efficacy-of-endoscopic-spray-cryotherapy-for-esophageal-cancer
#2
F C Tsai, S Ghorbani, B D Greenwald, S Jang, J A Dumot, M J McKinley, N J Shaheen, F Habr, H C Wolfsen, J A Abrams, C J Lightdale, N S Nishioka, M H Johnston, A Zfass, W J Coyle
Although surgery is traditionally the standard of care for esophageal cancer, esophagectomy carries significant morbidity. Alternative endoscopic therapies are needed for patients who are not candidates for conventional treatment. The objective of this study is to assess the safety, efficacy, and tolerability of spray cryotherapy of esophageal adenocarcinoma. This study includes patients with esophageal adenocarcinoma who had failed or were not candidates for conventional therapy enrolled retrospectively and prospectively in an open-label registry and patients in a retrospective cohort from 11 academic and community practices...
November 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28544177/giant-orf-tumor-in-an-immunocompromised-patient
#3
L Polivka, P Moguelet, J F Meritet, N Ouali, C Francès, P Senet
Herein, we report the efficacy and the safety of open-spray cryotherapy in an immunocompromised woman presenting with tumor-like orf lesion. A 58-year-old woman was referred with a 4-month history of an undiagnosed, painful, ulcerated, tumor-like lesion on the last phalanx of the fifth digit of her left hand. Six months earlier, the woman had received a cadaveric kidney transplant for an indication of focal segmental glomerulosclerosis. This article is protected by copyright. All rights reserved.
May 23, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28516110/large-bowel-obstruction-following-endoscopic-spray-cryotherapy-for-palliation-of-rectal-cancer-bleeding
#4
Ravi Prakash, Digant Gupta, Pankaj Vashi
We report a unique case of a 79-year-old woman with metastatic rectal cancer who developed bowel obstruction following endoscopic cryotherapy with liquid nitrogen for palliation of bleeding in the rectum. She developed abdominal distention and pain following the procedure. Computed tomography of the abdomen revealed a paraumbilical hernia containing a segment of transverse colon resulting in partial bowel obstruction. It appears that the recurrent freeze-thaw cycles with poor decompression of the colon despite active venting suction during cryotherapy may have resulted in bowel distention and collapse, causing conformational changes resulting in partial bowel obstruction due to a paraumbilical hernia...
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28446975/current-status-of-spray-cryotherapy-for-airway-disease
#5
REVIEW
Ryan F Moore, Deacon J Lile, Abbas E Abbas
The use of liquid nitrogen to treat skin and mucosal lesions is well understood in the dermatologic and gastrointestinal literature. Direct spray cryotherapy (SCT) in the airway has shown promising results in the treatment of esophageal premalignant and even invasive lesions. In the airway, several studies have shown it to be a safe, effective treatment for both benign and malignant disease. It is easily administered in the outpatient setting and can be repeated several times without undue side effects. In this article, we review the current literature on the use of SCT for the treatment of endobronchial lesions and also describe our own institutional experience of the use of SCT in the airway...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28434215/long-term-survival-in-stage-iv-esophageal-adenocarcinoma-with-chemoradiation-and-serial-endoscopic-cryoablation
#6
Zachary Spiritos, Parit Mekaroonkamol, Bassel F El-Rayes, Seth D Force, Steven A Keilin, Qiang Cai, Field F Willingham
Esophageal cancer has a poor overall prognosis and is frequently diagnosed at a late stage. Conventional treatment for metastatic esophageal cancer involves chemotherapy and radiation. Local disease control plays a significant role in improving survival. Endoscopic spray cryotherapy is a novel modality that involves freezing and thawing to produce local ablation of malignant tissue via ischemic mechanisms. Spray cryotherapy has been shown to be effective, particularly for early T-stage, superficial esophageal adenocarcinomas...
September 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28413772/postoperative-complications-with-cryotherapy-in-bone-tumors
#7
REVIEW
Clark Chen, John Garlich, Katie Vincent, Earl Brien
The technique of cryosurgery has been used to control local recurrence in a variety of benign and malignant bone tumors. Early studies revealed significant complication rates (25%) that included fracture, infection, and soft tissue injury. Our method of cryosurgery has yielded excellent tumor control with improved complication rates. The objective of this study is to determine the characteristics of postoperative complications after pouring liquid nitrogen into curettaged bone defects, and to review our current indications and surgical technique in bone tumor management...
June 2017: Journal of Bone Oncology
https://www.readbyqxmd.com/read/28358989/safety-and-histological-effect-of-liquid-nitrogen-metered-spray-cryotherapy-in-the-lung
#8
Dirk-Jan Slebos, David Breen, James Coad, Karin Klooster, Jorine Hartman, Robert Browning, Pallav L Shah, William H McNulty, Mohammed Al-Abdul Mohsin, Kashif Irshad
No abstract text is available yet for this article.
March 30, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28325539/n2-gas-egress-from-patients-airways-during-ln2-spray-cryotherapy
#9
John P O'Connor, Brian M Hanley, Thomas I Mulcahey, Ellen E Sheets, Kacey W Shuey
Spray cryotherapy using liquid nitrogen (LN2) is a general surgical tool used to ablate benign or malignant lesions. Adequate egress of the gaseous nitrogen (N2) generated during this process must be provided for safe use when LN2 is used within the body rather than topically. When delivered to either the gastrointestinal tract (requiring active venting via a suction tube) or body cavities open to room barometric pressure (such as lung airways) allowing for passive venting, the N2 gas generated from the boiling process must be evacuated...
March 18, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28255257/metered-cryospray%C3%A2-a-novel-uniform-controlled-and-consistent-in-vivo-application-of-liquid-nitrogen-cryogenic-spray
#10
Thomas I Mulcahey, James E Coad, Wei Li Fan, Daniel J Grasso, Brian M Hanley, Heather V Hawkes, Sean A McDermott, John P O'Connor, Ellen E Sheets, Charles J Vadala
In this article, a novel cryotherapy approach using a uniform, controlled, and consistent in vivo application of liquid nitrogen (LN2) spray as a Metered Cryospray(™) (MCS) process is described. Although MCS may be used for many potential clinical applications, this paper focuses on the development that led to the controlled and consistent delivery of radial LN2 cryogen spray in order to generate a uniform circumferential effect and how the amount of MCS can be adapted to specifically ablate targeted diseases within a patient's lumen such as an airway or esophagus...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/28235596/outcomes-after-liquid-nitrogen-spray-cryotherapy-in-barrett-s%C3%A2-esophagus-associated-high-grade-dysplasia-and%C3%A2-intramucosal-adenocarcinoma-5-year-follow-up
#11
Fariha H Ramay, Qingping Cui, Bruce D Greenwald
BACKGROUND AND AIMS: Liquid nitrogen spray cryotherapy (LNSCT) has been shown to be a safe, well-tolerated, and effective therapy for Barrett's esophagus (BE)-associated high-grade dysplasia (BE-HGD) and intramucosal adenocarcinoma (IMC). Long-term follow-up is lacking. AIMS: The aim of this study was to assess the efficacy, durability, and rate of neoplastic progression after LNSCT in BE-HGD/IMC at 3 and 5 years. METHODS: In this single-center, retrospective study drawn from a prospective database, patients with BE-HGD/IMC of any length treated with LNSCT were followed with surveillance endoscopy with biopsy for 3 to 5 years...
October 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27873145/use-of-refrigerant-spray-of-a-propane-butane-isobutane-gas-mixture-in-the-management-of-keratocystic-odontogenic-tumors-a-preliminary-study
#12
Eduardo Luis de Souza Cruz, Ana Karla da Silva Tabosa, Aline Semblano Carreira Falcão, Talita Tartari, Lucas Machado de Menezes, Edmar Tavares da Costa, José Thiers Carneiro Júnior
PURPOSE: Keratocystic odontogenic tumor (KCOT) is an aggressive benign tumor and the management by complete enucleation followed by cryotherapy maintains the inorganic bone matrix, resulting in better repair and reduces the rates of recurrence. A refrigerant spray with a propane/butane/isobutane gas mixture has been pointed to as an alternative to liquid nitrogen, because the device is easy to handle and contain within the cavity, providing better control and lower risk of injury to the adjacent soft tissue...
March 2017: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27763916/hemodynamic-instability-following-airway-spray-cryotherapy
#13
Alessia Pedoto, Dawn P Desiderio, David Amar, Robert J Downey
BACKGROUND: Spray cryotherapy (SCT) of airway lesions is used to effectively palliate respiratory symptoms related to airway obstruction, but significant intraoperative hemodynamic complications have been noted. We reviewed the experience at a single institution using SCT for the treatment of obstructive airway tumors. METHODS: A retrospective review of a single institution experience with intraoperative and postoperative hemodynamic complications associated with SCT was performed...
November 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27761276/advantages-of-pressurized-spray-cryosurgery-in-giant-cell-tumors-of-the-bone
#14
Nevzat Dabak, Hasan Göçer, Alper Çıraklı
BACKGROUND: Giant Cell Tumor is considered a benign, local and aggressive tumor. Although considered a benign bone tumor, it is still the subject of discussion and research because of the associated local bone destruction, as well as high rates of recurrence and distant metastases. Options are being developed for both surgical techniques and adjuvant therapies. AIMS: The present study evaluated the administration of cryotherapy via a pressurized-spray technique in giant cell tumors of the bone...
September 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27662476/the-application-of-liquid-nitrogen-spray-cryotherapy-in-treatment-of-bronchial-stenosis
#15
Kelly J Janke, Abbas El-Sayed Abbas, Vishnu Ambur, Daohai Yu
OBJECTIVE: Spray cryotherapy (SCT), the application of liquid nitrogen in a noncontact form, has been demonstrated to have efficacy in treating various types of pathologic lesions of the airway when used as an adjunct with bronchoscopy. The purpose of the study was to evaluate the results of the use of bronchoscopic SCT on the airway in a single institution. METHODS: We performed a retrospective review of data collected on all patients who underwent SCT to re-establish or improve airway patency in an 11-month period...
September 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27532803/treatment-of-benign-tracheal-stenosis-using-endoluminal-spray-cryotherapy
#16
Faiz Y Bhora, Adil Ayub, Craig M Forleiter, Chyun-Yin Huang, Khalid Alshehri, Sadiq Rehmani, Adnan M Al-Ayoubi, Wissam Raad, Robert S Lebovics
Importance: Tracheal stenosis is a debilitating disorder with heterogeneity in terms of disease characteristics and management. Repeated recurrences substantially alter patients' quality of life. There is limited evidence for the use of spray cryotherapy (SCT) in the management of benign airway disease. Objective: To report our early results for the use of SCT in patients with benign tracheal stenosis. Design, Setting, and Participants: Data were extracted from the medical records of a consecutive series of patients with benign airway stenosis secondary to granulomatosis with polyangiitis (GPA) (n = 13), prior tracheotomy or tracheal intubation (n = 8), and idiopathic strictures (n = 5) treated from September 1, 2013, to September 30, 2015, at a tertiary care hospital...
November 1, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27284325/treatment-of-condyloma-acuminata-in-pregnant-women-with-cryotherapy-combined-with-proanthocyanidins-outcome-and-safety
#17
Li-Juan Yang, Dong-Ning Zhu, Yan-Ling Dang, Xiong Zhao
Patients with condyloma acuminata (CA) during pregnancy represent a special risk group. The outcomes of many treatment methods for such cases are not satisfactory. The purpose of the present study was to evaluate the treatment outcome and safety of cryotherapy combined with proanthocyanidins (PCs) for CA in pregnant women. In this study, 46 pregnant women with CA were treated with cryotherapy combined with PCs. The lesions were sprayed with liquid nitrogen until the color of the wart changed from flesh colored to purple...
June 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27268274/bronchoscopic-cryotherapy-clinical-applications-of-the-cryoprobe-cryospray-and-cryoadhesion
#18
David M DiBardino, Anthony R Lanfranco, Andrew R Haas
Cryotherapy is an evolving therapeutic and diagnostic tool used during bronchoscopy. Through rapid freeze-thaw cycles, cryotherapy causes cell death and tissue necrosis or tissue adherence that can be used via the flexible or rigid bronchoscope. This extreme cold can be used through the working channel of the bronchoscope via a specialized cryoprobe or directly with the use of spray cryotherapy. These properties allow for multiple bronchoscopic techniques, each with its own equipment and procedural, safety, and efficacy considerations...
August 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27130380/partial-matricectomy-with-cryotherapy-in-treatment-of-ingrown-toenails
#19
Ahmet Yılmaz, Erol Çenesizoğlu
OBJECTIVE: The aim of this study was to investigate the effectiveness of cryotherapy applied for the purpose of matricectomy following partial nail removal in treatment of ingrown nails. METHODS: Between 2010 and 2013, 76 ingrown toenails of 62 patients were included in this prospective study. Following partial toenail removal, matricectomy with cryotherapy was performed. The lateral nail matrix was frozen for 45 seconds with open spray and spot-freezing technique using liquid nitrogen...
2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27127370/liquid-nitrogen-cryotherapy-in-recalcitrant-alopecia-areata-a-study-of-11-patients
#20
Vijay P Zawar, Gayatri Mukund Karad
CONTEXT: Recalcitrant alopecia areata (AA) is not uncommon in clinical practice. In certain patients, treatment failures are known with almost every conventional therapy either singly or in combination. AIMS: To study the efficacy of liquid nitrogen (LN) cryotherapy in patients with recalcitrant AA. SUBJECTS AND METHODS: We present series of eleven patients of recalcitrant AA, who consulted us after getting no response to various modalities of treatment for 6 months...
January 2016: International Journal of Trichology
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