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https://www.readbyqxmd.com/read/29222741/exploratory-study-of-barriers-to-successful-office-contacts-for-attention-deficit-hyperactivity-disorder
#1
Jayde T Hooven, Benjamin N Fogel, James G Waxmonsky, Deepa L Sekhar
The American Academy of Pediatrics published attention deficit hyperactivity disorder (ADHD) guidelines, but significant variability exists in care. This exploratory study aimed to understand barriers to compliance with primary care office contacts for ADHD medication management. The study was conducted at a single academic medical center via retrospective chart review between 6/1/15 and 5/31/16 in combination with telephone interviews. Participants included 306 children 6-12 years old with an ADHD-related ICD-9/ICD-10 diagnosis...
December 8, 2017: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/29222486/the-role-of-personality-and-subjective-exposure-experiences-in-posttraumatic-stress-disorder-and-depression-symptoms-among-children-following-wenchuan-earthquake
#2
Xiacan Chen, Jiajun Xu, Bin Li, Na Li, Wanjun Guo, Mao-Sheng Ran, Jun Zhang, Yanchun Yang, Junmei Hu
This study aims to investigate the role of personality traits and subjective exposure experiences in posttraumatic stress disorder and depression symptoms. In Qingchuan, 21,652 children aged 7 to 15 years were assessed using face-to-face interviews one year after the Wenchuan earthquake in China. The Junior Eysenck Personality Questionnaire, a modified earthquake exposure scale, the UCLA Posttraumatic Stress Disorder Reaction Index (adolescent), and the Adolescent Depression Inventory were used to assess personality characteristics, trauma experiences, posttraumatic stress disorder and depression symptoms, respectively...
December 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29221579/biomarkers-in-connective-tissue-diseases
#3
REVIEW
Neelakshi R Jog, Judith A James
Autoimmune connective tissue diseases are clinically variable, making biomarkers desirable for assessing future disease risk, supporting early and accurate diagnosis, monitoring disease activity and progression, selecting therapeutics, and assessing treatment response. Because of their correlations with specific clinical characteristics and often with disease progression, autoantibodies and other soluble mediators are considered potential biomarkers. Additional biomarkers might reflect downstream pathologic processes or appear because of ongoing inflammation and damage...
December 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29221477/trajectories-and-characteristics-of-functional-impairment-before-and-after-suicide-attempt-in-young-adults-a-nationwide-register-based-cohort-study
#4
Mo Wang, Magnus Helgesson, Syed Rahman, Thomas Niederkrotenthaler, Ellenor Mittendorfer-Rutz
BACKGROUND: Despite high rates of youth suicide attempt, little is known about patterns of functional impairment in terms of sickness absence and disability pension (SA/DP) before and after an attempt. The aim was to identify SA/DP trajectories among young adults with or without suicide attempt and to describe associations of socio-demographic and clinical factors with such trajectories. METHODS: This is a population-based cohort study of 5385 individuals aged 25-40 years with a first suicide attempt during 2007-2009...
December 8, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29220694/impulsive-responding-in-threat-and-reward-contexts-as-a-function-of-ptsd-symptoms-and-trait-disinhibition
#5
Naomi Sadeh, Jeffrey M Spielberg, Jasmeet P Hayes
We examined current posttraumatic stress disorder (PTSD) symptoms, trait disinhibition, and affective context as contributors to impulsive and self-destructive behavior in 94 trauma-exposed Veterans. Participants completed an affective Go/No-Go task (GNG) with different emotional contexts (threat, reward, and a multidimensional threat/reward condition) and current PTSD, trait disinhibition, and risky/self-destructive behavior measures. PTSD interacted with trait disinhibition to explain recent engagement in risky/self-destructive behavior, with Veterans scoring high on trait disinhibition and current PTSD symptoms reporting the highest levels of these behaviors...
November 1, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29219937/relationship-between-maternal-characteristics-and-postpartum-hemorrhage-a-meta-analysis-study
#6
Aysegul Durmaz, Nuran Komurcu
BACKGROUND: Postpartum hemorrhage (PPH) is a leading cause of maternal death in low-income countries and the primary cause of approximately one of every four maternal deaths worldwide. PURPOSE: The aim of this study was to determine the antenatal risk factors of PPH and its effects. METHODS: The literature from nine databases was reviewed, and studies published between 2000 and 2012 were analyzed using terms such as "postpartum hemorrhage," "prevention of postpartum hemorrhage," and "management of postpartum hemorrhage...
December 6, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29218870/loss-of-function-of-neuroplasticity-related-genes-confers-risk-for-human-neurodevelopmental-disorders
#7
Milo R Smith, Benjamin S Glicksberg, Li Li, Rong Chen, Hirofumi Morishita, Joel T Dudley
High and increasing prevalence of neurodevelopmental disorders place enormous personal and economic burdens on society. Given the growing realization that the roots of neurodevelopmental disorders often lie in early childhood, there is an urgent need to identify childhood risk factors. Neurodevelopment is marked by periods of heightened experience-dependent neuroplasticity wherein neural circuitry is optimized by the environment. If these critical periods are disrupted, development of normal brain function can be permanently altered, leading to neurodevelopmental disorders...
2018: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/29218840/behaviour-vs-perception-an-investigation-into-the-components-of-emotional-invalidation
#8
Meredith Elzy, Marc Karver
BACKGROUND: The negative effects of emotionally invalidating environments are theorized by the biosocial theory of borderline personality disorder to be vast and severe. However, findings from studies on the impact of emotional invalidation (EI) vary, perhaps due to different operational definitions of EI. The current investigation seeks to explore the relationship between the objective behavioural observations of EI and recipient's subjective perceptions of experiencing these behaviours...
December 8, 2017: Personality and Mental Health
https://www.readbyqxmd.com/read/29218455/the-primary-cilium-once-a-rudimentary-organelle-that-is-now-a-ubiquitous-sensory-cellular-structure-involved-in-many-pathological-disorders
#9
Denys N Wheatley
This article looks mostly at the steps that have led to the primary cilium finding its place in our understanding of cell biology, developmental biology, and medical syndromes due to its aberrations. It is a personal account that stresses, if nothing else, the value of the adage "stick to your guns". My obsession with this organelle, following on from fascination with the centriole, has led to a whole career devoted to determining the nature and role of primary cilia in basic cell biology, which has proved much more important than had been appreciated for almost a century...
December 7, 2017: Journal of Cell Communication and Signaling
https://www.readbyqxmd.com/read/29217971/evaluation-of-the-relationship-between-the-occlusion-parameters-and-symptoms-of-the-temporomandibular-joint-disorder
#10
Agnė Dzingutė, Gaivilė Pileičikienė, Aušra Baltrušaitytė, Gediminas Skirbutis
Background: The aetiology of temporomandibular joint disorders (TMD) is multifactorial, whereas occlusal disharmony is one of the predisposing factors. Researchers still discuss the relation between occlusion and TMD. Objective: The study aims to investigate the relation between static occlusal parameters and TMD clinical symptoms using T-Scan II analysis system. Material and methods: The sample consisted of 44 persons divided into the treatment group of 20 TMD patients and the control group of 24 subjects without TMD...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29217517/assessment-of-child-or-young-person-with-a-possible-eating-disorder
#11
Helen Bould, Claudia Newbegin, Mina Fazel, Anne Stewart, Alan Stein
No abstract text is available yet for this article.
December 7, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29217452/specific-agreement-on-ordinal-and-multiple-nominal-outcomes-can-be-calculated-for-more-than-two-raters
#12
Henrica C W de Vet, Margriet G Mullender, Iris Eekhout
OBJECTIVE: The concept of specific agreement has been proposed for dichotomous outcomes for two and more raters. We aim to extend this concept for variables with more than two ordinal or nominal categories and more than two raters. STUDY DESIGN AND SETTING: We used two data sets: 4 plastic surgeons classifying photographs after breast reconstruction on a 5 point ordinal scale; and 6 raters classifying psychiatric patients into 5 diagnostic categories. For m raters, all (i...
December 4, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29216570/the-effects-of-alcohol-hangover-on-future-drinking-behavior-and-the-development-of-alcohol-problems
#13
Kelly E Courtney, Matthew Worley, Norma Castro, Susan F Tapert
INTRODUCTION: Alcohol hangover experiences in young adulthood have been shown to predict more subsequent alcohol problems. Hangover susceptibility appears to be partially heritable and related to family history of alcohol use disorders. However, very little is known about the developmental course of these associations and whether they are accounted for by an individual's drinking history. The goal of this study is to investigate the prospective and unique relationships between family history of alcohol use disorders, severity of alcohol hangover experiences in adolescence, and later alcohol use and related problems measured over 13years...
November 28, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29215903/clinician-ratings-of-vulnerable-and-grandiose-narcissistic-features-implications-for-an-expanded-narcissistic-personality-disorder-diagnosis
#14
Kasey Stanton, Mark Zimmerman
Conceptualizations of narcissistic personality disorder (NPD) in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (American Psychiatric Association, 2013) have been criticized for focusing too exclusively on grandiose narcissistic traits (e.g., exploitativeness and entitlement) and failing to capture vulnerable narcissistic features (e.g., feelings of inadequacy). We extended prior grandiose and vulnerable narcissism research by examining the degree to which clinician ratings of traits related to grandiosity overlapped with traits related to vulnerability in a large sample of adult outpatients (N = 2,149)...
December 7, 2017: Personality Disorders
https://www.readbyqxmd.com/read/29215902/words-matter-implementing-the-electronically-activated-recorder-in-schizotypy
#15
Kyle S Minor, Beshaun J Davis, Matthew P Marggraf, Lauren Luther, Megan L Robbins
In schizophrenia-spectrum populations, analyzing the words people use has offered promise for unlocking information about affective states and social behaviors. The electronically activated recorder (EAR) is an application-based program that is combined with widely used smartphone technology to capture a person's real-world interactions via audio recordings. It improves on the ecological validity of current methodologies by providing objective and naturalistic samples of behavior. This study is the first to implement the EAR in people endorsing elevated traits of schizophrenia-spectrum personality disorders (i...
December 7, 2017: Personality Disorders
https://www.readbyqxmd.com/read/29215901/introduction-of-the-dsm-5-levels-of-personality-functioning-questionnaire
#16
Steven K Huprich, Sharon M Nelson, Kevin B Meehan, Caleb J Siefert, Gregory Haggerty, James Sexton, V Barry Dauphin, Matthew Macaluso, Jennifer Jackson, Rosey Zackula, Lyle Baade
With the introduction in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) of a hybrid system of personality disorder assessment, the ability to assess patients' traits, as well as their level of personality functioning, has become increasingly important. To assess this criterion, the DSM-5 Levels of Personality Functioning Questionnaire (DLOPFQ) was developed. The DLOPFQ assesses individuals' self-impairments and other impairments in several domains (self-direction, identity, empathy, and intimacy) and across 2 contexts (work/school and relationships)...
December 7, 2017: Personality Disorders
https://www.readbyqxmd.com/read/29215397/keratoconus-and-personality-a-review
#17
Mark J Mannis, Jennifer J Ling, Ralph Kyrillos, Melissa Barnett
PURPOSE: To assess the existing literature on the subject of keratoconus and personality and to propose a theory that might account for the perceived personality changes associated with this condition. METHODS: A literature search was conducted in the PubMed database using the term "keratoconus" in combination with keywords such as personality, psychiatry, psychology, anxiety, depression, or psychosis. A total of 15 articles pertaining to personality and psychiatric disorders in keratoconus were retained and reviewed...
December 5, 2017: Cornea
https://www.readbyqxmd.com/read/29214869/the-relationship-between-the-personality-inventory-for-the-dsm-5-pid-5-and-the-psychotic-disorder-in-a-clinical-sample
#18
Tim Bastiaens, Dirk Smits, Marc De Hert, Erik Thys, Hendrik Bryon, Kim Sweers, Teresa Teugels, Joeri Van Looy, Tim Verwerft, Dominique Vanwalleghem, Ludi Van Bouwel, Laurence Claes
Recent studies have successfully investigated the validity of the DSM-5 Alternative Model for Personality Disorders. In a final sample of 174 psychiatric patients, the present study examined the relationship between the Personality Inventory for the DSM-5 (PID-5) and syndromal psychosis. Results showed that patients diagnosed with versus without a psychotic disorder significantly differed on all PID-5 domains except Antagonism. Discriminant function analysis indicated that lower Detachment, lower Negative Affect, lower Disinhibition, and higher Psychoticism best discriminated patients with a psychotic disorder from patients with other psychiatric conditions...
February 1, 2017: Assessment
https://www.readbyqxmd.com/read/29214564/undiagnosed-diseases-italy-us-collaboration-and-international-efforts-to-tackle-rare-and-common-diseases-lacking-a-diagnosis
#19
Domenica Taruscio, Giovanna Floridia, Marco Salvatore, Stephen C Groft, William A Gahl
Rare diseases (RD), according to European Union criteria, affect 5 per 10,000 persons, or 30 million people, in the EU; in the USA, RD are defined as conditions that affect fewer than 200,000 individuals in the population (320 million). Most known rare disorders are severe and chronic, with many being degenerative and life threatening. There are roughly 5000-8000 rare diseases (European Commission, DG Health and Food Safety, Public Health, Rare Diseases, Policy.http://ec.europa.eu/health/rare_diseases/policy/index_en...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29214289/treated-incidence-of-psychotic-disorders-in-the-multinational-eu-gei-study
#20
Hannah E Jongsma, Charlotte Gayer-Anderson, Antonio Lasalvia, Diego Quattrone, Alice Mulè, Andrei Szöke, Jean-Paul Selten, Caitlin Turner, Celso Arango, Ilaria Tarricone, Domenico Berardi, Andrea Tortelli, Pierre-Michel Llorca, Lieuwe de Haan, Julio Bobes, Miguel Bernardo, Julio Sanjuán, José Luis Santos, Manuel Arrojo, Cristina Marta Del-Ben, Paulo Rossi Menezes, Robin M Murray, Bart P Rutten, Peter B Jones, Jim van Os, Craig Morgan, James B Kirkbride
Importance: Psychotic disorders contribute significantly to the global disease burden, yet the latest international incidence study of psychotic disorders was conducted in the 1980s. Objectives: To estimate the incidence of psychotic disorders using comparable methods across 17 catchment areas in 6 countries and to examine the variance between catchment areas by putative environmental risk factors. Design, Setting, and Participants: An international multisite incidence study (the European Network of National Schizophrenia Networks Studying Gene-Environment Interactions) was conducted from May 1, 2010, to April 1, 2015, among 2774 individuals from England (2 catchment areas), France (3 catchment areas), Italy (3 catchment areas), the Netherlands (2 catchment areas), Spain (6 catchment areas), and Brazil (1 catchment area) with a first episode of nonorganic psychotic disorders (International Statistical Classification of Diseases and Related Health Problems, Tenth Revision [ICD-10] codes F20-F33) confirmed by the Operational Criteria Checklist...
December 6, 2017: JAMA Psychiatry
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