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Bone anatomy

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https://www.readbyqxmd.com/read/29786142/the-bone-marrow-is-not-only-a-primary-lymphoid-organ-the-critical-role-for-t-lymphocyte-migration-and-housing-of-long-term-memory-plasma-cells
#1
REVIEW
Reinhard Pabst
In immunology and anatomy textbooks the bone marrow is described as a typical "primary lymphoid organ" producing lymphoid cells independent of antigens. The hematopoietic bone marrow is largely age-dependent organ with great anatomical and functional differences among various species. There are estimates that about 12 % of all lymphoid cells in the human body are found in the bone marrow at any given time (2 % in the peripheral blood). Enormous numbers of T lymphocytes migrate to the bone marrow and partly return later to the blood...
May 22, 2018: European Journal of Immunology
https://www.readbyqxmd.com/read/29781818/lower-extremity-megaprostheses-in-orthopaedic-oncology
#2
Santiago A Lozano Calderón, Joseph Kuechle, Kevin A Raskin, Francis J Hornicek
The megaprosthesis is designed to reproduce the form and function of a removed or lost large segment of bone and accompanying soft tissues. Slow but substantial improvements in the design and surgical implementation of these devices have advanced the capacity to restore patients' functional abilities. The essential challenges include identifying the ideal materials, bonding these materials to bone and soft tissues, reproducing functional anatomy, and adapting to the growing skeleton. Failure of these devices can result from soft-tissue insufficiency, aseptic loosening, structural failures, infection, and tumor recurrence...
May 17, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29777918/sex-differences-in-the-spatial-distribution-of-bone-in-relation-to-incident-hip-fracture-findings-from-the-ages-reykjavik-study
#3
Elisa A Marques, Julio Carballido-Gamio, Vilmundur Gudnason, Gunnar Sigurdsson, Sigurdur Sigurdsson, Thor Aspelund, Kristin Siggeirsdottir, Lenore Launer, Gudny Eiriksdottir, Thomas Lang, Tamara B Harris
In this case-cohort study, we used data-driven computational anatomy approaches to assess within and between sex spatial differences in proximal femoral bone characteristics in relation to incident hip fracture. One hundred male and 234 female incident hip fracture cases, and 1047 randomly selected noncase subcohort participants (562 female) were chosen from the population-based AGES-Reykjavik study (mean age of 77 years). The baseline -i.e. before hip fracture- hip quantitative computed tomography scans of these subjects were analyzed using voxel-based morphometry, tensor-based morphometry, and surface-based statistical parametric mapping to assess the spatial distribution of volumetric bone mineral density (vBMD), internal structure, and cortical bone properties (thickness, vBMD and trabecular vBMD adjacent to the endosteal surface) of the proximal femur, respectively, in relation to incident hip fracture...
May 16, 2018: Bone
https://www.readbyqxmd.com/read/29777422/patellofemoral-cartilage-repair
#4
REVIEW
Alexandre Barbieri Mestriner, Jakob Ackermann, Andreas H Gomoll
PURPOSE OF REVIEW: This review provides an overview of well-established and newly developed cartilage repair techniques for cartilage defects in the patellofemoral joint (PFJ). An algorithm will be presented for approaching cartilage defects considering the distinct anatomy of both the patellar and trochlear articular surfaces. RECENT FINDINGS: Recent studies on cartilage repair in the PFJ have demonstrated improved outcomes in an attempt to delay or obviate the need for arthroplasty, and improve symptoms in young patients...
May 18, 2018: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/29771958/cooperation-of-bmp-and-ihh-signaling-in-interdigital-cell-fate-determination
#5
Arunima Murgai, Sara Altmeyer, Stephanie Wiegand, Przemko Tylzanowski, Sigmar Stricker
The elaborate anatomy of hands and feet is shaped by coordinated formation of digits and regression of the interdigital mesenchyme (IM). A failure of this process causes persistence of interdigital webbing and consequently cutaneous syndactyly. Bone morphogenetic proteins (BMPs) are key inductive factors for interdigital cell death (ICD) in vivo. NOGGIN (NOG) is a major BMP antagonist that can interfere with BMP-induced ICD when applied exogenously, but its in vivo role in this process is unknown. We investigated the physiological role of NOG in ICD and found that Noggin null mice display cutaneous syndactyly and impaired interdigital mesenchyme specification...
2018: PloS One
https://www.readbyqxmd.com/read/29759935/applied-anatomy-of-round-window-and-adjacent-structures-of-tympanum-related-to-cochlear-implantation
#6
Shraddha Jain, Sagar Gaurkar, Prasad T Deshmukh, Mohnish Khatri, Sanika Kalambe, Pooja Lakhotia, Deepshikha Chandravanshi, Ashish Disawal
INTRODUCTION: Various aspects of the round window anatomy and anatomy of posterior tympanum have relevant implications for designing cochlear implant electrodes and visualizing the round window through facial recess. Preoperative information about possible anatomical variations of the round window and its relationships to the adjacent neurovascular structures can help reduce complications in cochlear implant surgery. OBJECTIVE: The present study was undertaken to assess the common variations in round window anatomy and the relationships to structures of the tympanum that may be relevant for cochlear implant surgery...
April 19, 2018: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29756497/relationship-between-muscular-and-bony-anatomy-in-native-hips-a-theoretical-background-for-approach-specific-implant-positioning
#7
Doruk Akgün, Philipp von Roth, Tobias Winkler, Carsten Perka, Adam Trepczynski, Bernd Preininger
INTRODUCTION: The aim of this study was to analyse the relationship between bony joint orientation and the distribution of hip musculature. METHODS: The bone anatomy of the hip (femoral antetorsion (AT), acetabular anteversion (AV), and combined anteversion (AV/AT)) and the muscle volume of the gluteal muscles and the tensor fasciae latae were analysed bilaterally using computed tomography data of 49 patients. Muscle force direction (MFD) was determined for each muscle...
May 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29755236/posterior-identification-and-exposure-of-the-v3-segment-of-the-vertebral-artery
#8
Ali Nourbakhsh, Nicholas W Wiegers, Francis H Shen
Objective: The purpose of this study was to define the anatomy of the V3 segment of the vertebral artery (VA) from the posterior approach. Methods: Ten formalin-fixed cadavers were carefully dissected bilaterally using landmark features to identify and safely expose the VA from the posterior. Measurements regarding morphometric characteristics of landmark features and feasible resection quantifications were obtained and analyzed. The C2 pars was resected completely in all cadavers, averaging 15...
January 2018: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29750708/endometrioid-adenocarcinoma-with-solitary-metastasis-to-the-appendix-mimicking-primary-appendiceal-adenocarcinoma-a-case-report-and-literature-review
#9
Qiujie Ma, Jianshe Wu
Metastatic tumors of the appendix are rare. Endometrial cancer tends to metastasize by directly invading neighboring structures; the lung, liver, bones, and brain are common sites of distant metastasis. Herein, we present a case of a solitary endometrial metastatic tumor in the appendiceal mucosa without serosal involvement that mimicked a primary adenocarcinoma of the appendix. The patient who had undergone a radical hysterectomy for an endometrioid adenocarcinoma 3 years earlier presented to the hospital with a history of persistent right-lower abdominal pain...
May 10, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29746490/clinical-evaluation-of-semi-automatic-open-source-algorithmic-software-segmentation-of-the-mandibular-bone-practical-feasibility-and-assessment-of-a-new-course-of-action
#10
Jürgen Wallner, Kerstin Hochegger, Xiaojun Chen, Irene Mischak, Knut Reinbacher, Mauro Pau, Tomislav Zrnc, Katja Schwenzer-Zimmerer, Wolfgang Zemann, Dieter Schmalstieg, Jan Egger
INTRODUCTION: Computer assisted technologies based on algorithmic software segmentation are an increasing topic of interest in complex surgical cases. However-due to functional instability, time consuming software processes, personnel resources or licensed-based financial costs many segmentation processes are often outsourced from clinical centers to third parties and the industry. Therefore, the aim of this trial was to assess the practical feasibility of an easy available, functional stable and licensed-free segmentation approach to be used in the clinical practice...
2018: PloS One
https://www.readbyqxmd.com/read/29741560/combined-nasal-osteotomies-with-caudal-transverse-osteotomy-and-their-effect-on-dorsal-geometry
#11
Ersoy Konas, Ozan Bitik
Background: Congenital, traumatic, or developmental bony vault deformities may require additional interventions rather than classical osteotomies to correct the surface structure or angulations of the nasal bones in rhinoplasty. Objectives: The aim of the study was to determine the effects of the additional osteotomies applied for the correction of the nasal vault asymmetries retrospectively. Methods: Twenty-one patients among 512 primary rhinoplasty cases between 2011-2016 with bony vault asymmetries were included into the study...
May 8, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29736586/large-animal-models-for-osteochondral-regeneration
#12
Isabel R Dias, Carlos A Viegas, Pedro P Carvalho
Namely, in the last two decades, large animal models - small ruminants (sheep and goats), pigs, dogs and horses - have been used to study the physiopathology and to develop new therapeutic procedures to treat human clinical osteoarthritis. For that purpose, cartilage and/or osteochondral defects are generally performed in the stifle joint of selected large animal models at the condylar and trochlear femoral areas where spontaneous regeneration should be excluded. Experimental animal care and protection legislation and guideline documents of the US Food and Drug Administration, the American Society for Testing and Materials and the International Cartilage Repair Society should be followed, and also the specificities of the animal species used for these studies must be taken into account, such as the cartilage thickness of the selected defect localization, the defined cartilage critical size defect and the joint anatomy in view of the post-operative techniques to be performed to evaluate the chondral/osteochondral repair...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29735291/chimeric-medial-femoral-condyle-osteocutaneous-flap-for-reconstruction-of-multiple-metacarpal-defects
#13
REVIEW
Chung-Chen Hsu, James Tseng, Yu-Te Lin
When faced with reconstructing metacarpal defects, various options have been described. We describe a chimeric medial femoral condyle osteocutaneous flap as a new method for providing multiple bone grafts as well as soft tissue coverage in a single stage. The medial femoral condyle has become an area of increased interest given the versatility it allows in harvesting the bone. This osteocutaneous flap is useful when reconstructing small- to medium-sized adjacent metacarpal bone defects. The chimeric design of the flap lends flexibility at the time of inset that is absent for other options of vascularized bone grafts...
May 5, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29730457/anterior-posterior-length-discrepancy-of-the-spinal-column-in-adolescent-idiopathic-scoliosis-a-3d-ct-study
#14
Rob C Brink, Tom P C Schlösser, Marijn van Stralen, Koen L Vincken, Moyo C Kruyt, Steve C N Hui, Max A Viergever, Winnie C W Chu, Jack C Y Cheng, René M Castelein
BACKGROUND CONTEXT: One of the characteristics of reported observations in adolescent idiopathic scoliosis (AIS) is that the thoracic spine is longer anteriorly than posteriorly, more pronounced around the apex than the transitional zones. This reversal of the normal kyphotic anatomy of the thoracic spine is related to questions of etiopathogenesis of AIS. The changes in the anatomy of the anterior column have been described rather in detail, however, the role of the posterior spinal column and the laminae has so far not been elucidated...
May 3, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29730061/computed-tomographic-angiographic-perforator-localization-for-virtual-surgical-planning-of-osteocutaneous-fibular-free-flaps-in-head-and-neck-reconstruction
#15
Kyle S Ettinger, Amy E Alexander, Kevin Arce
Virtual surgical planning (VSP), computer-aided design and computer-aided modeling, and 3-dimensional printing are 3 distinct technologies that have become increasingly used in head and neck oncology and microvascular reconstruction. Although each of these technologies has long been used for treatment planning in other surgical disciplines, such as craniofacial surgery, trauma surgery, temporomandibular joint surgery, and orthognathic surgery, its widespread use in head and neck reconstructive surgery remains a much more recent event...
April 10, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29728742/in-vivo-three-dimensional-mr-imaging-of-the-intact-anterior-cruciate-ligament-shows-a-variable-insertion-pattern-of-the-femoral-and-tibial-footprints
#16
S U Scheffler, K Maschewski, R Becker, P Asbach
PURPOSE: Failure to reconstruct the natural footprints of the ruptured anterior cruciate ligament (ACL) may lead to premature graft-failure. Therefore, precise analyses of insertion site anatomy and inter-individual variations of the morphology of the ACL are highly important to facilitate optimal individualized graft placement. Therefore, the purpose of this study was to analyze the inter-individual variation of the morphology of the femoral and tibial ACL footprints. METHODS: Thirty subjects with an intact ACL were included in this study for MR imaging of their knee joint...
May 4, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29728433/focal-osteopenia-of-pubic-parasymphyseal-bone-as-an-underlying-cause-of-groin-pain-in-sports-a-new-perspective
#17
Alexandra Dimitrakopoulou, Ernest Schilders
Groin pain is a common problem in athletes. The diagnosis can be difficult because of the complexity of the groin anatomy, the numerous clinical entities presenting with similar symptoms, the concurrence of those entities and the confusing terminology. Thus, a dilemma in diagnosis may arise leading to long-standing symptoms, disabling groin pain, mismanagement and therefore to poor treatment. Hereby, we present such a case of a recreational athlete complaining for excruciate pubic pain after being misdiagnosed and subsequently mistreated affecting her quality of life...
May 4, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29727335/spinopelvic-fixation
#18
Sean M Esmende, Kalpit N Shah, Alan H Daniels
Fixation at the lumbosacral junction continues to be a challenge for spine surgeons despite advances in spinal instrumentation techniques. The poor bone quality of the sacrum, the complex regional anatomy, and the tremendous biomechanical forces at the lumbosacral junction contribute to the high rates of instrumentation-related complications. Although many spinopelvic fixation techniques have been reported, only a few are still widely used because of the high complication rates associated with previous techniques...
June 1, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29726793/sublaminar-fixation-for-traumatic-lumbar-fracture-subluxation-with-lateral-listhesis-in-a-2-year-old-patient
#19
Daniel S Yanni, Aurora S Cruz, Alexander Y Halim, Amandip S Gill, Michael G Muhonen, Robert F Heary, Ira M Goldstein
Pediatric spinal trauma can present a surgeon with difficult management decisions given the rarity of these cases, pediatric anatomy, and a growing spine. The need to stabilize a traumatically unstable pediatric spine can be an operative challenge given the lack of instrumentation available. The authors present a surgical technique and an illustrative case that may offer a novel, less disruptive method of stabilization. A 2-year-old girl presented after an assault with an L1-2 fracture subluxation with lateral listhesis and fractured jumped facets exhibited on CT scans...
May 4, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29726018/hitherto-unknown-detailed-muscle-anatomy-in-an-8-week-old-embryo
#20
Moritz V Warmbrunn, Bernadette S de Bakker, Jaco Hagoort, Pauline B Alefs-de Bakker, Roelof-Jan Oostra
Congenital muscle diseases, such as myopathies or dystrophies, occur relatively frequently, with estimated incidences of up to 4.7 per 100 000 newborns. To diagnose congenital diseases in the early stages of pregnancy, and to interpret the results of increasingly advanced in utero imaging techniques, a profound knowledge of normal human morphological development of the locomotor system and the nervous system is necessary. Muscular development, however, is an often neglected topic or is only described in a general way in embryology textbooks and papers...
May 3, 2018: Journal of Anatomy
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