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https://www.readbyqxmd.com/read/28424459/development-and-outcomes-of-a-primary-care-based-sleep-assessment-service-in-canterbury-new-zealand
#1
Michael J Epton, Paul T Kelly, Brett I Shand, Sallyanne V Powell, Judith N Jones, Graham R B McGeoch, Michael C Hlavac
Prior to 2007, increasing demand for sleep services, plus inability to adequately triage severity, led to long delays in sleep assessment and accessing continuous positive airway pressure. We established a community sleep assessment service carried out by trained general practices using a standardised tool and overnight oximetry. All cases were discussed at a multi-disciplinary meeting, with four outcomes: severe obstructive sleep apnoea treated with continuous positive airway pressure; investigation with more complex studies; sleep physician appointment; no or non-severe sleep disorder for general practitioner management...
April 19, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28414584/screening-commercial-vehicle-drivers-for-obstructive-sleep-apnea-tools-barriers-and-recommendations
#2
Kelly A Evans, Tracey Yap, Barbara Turner
Obstructive sleep apnea (OSA) is a disorder characterized by a cessation of breathing during sleep, leading to poor sleep patterns and daytime somnolence. Daytime somnolence is of particular concern for commercial vehicle drivers, whose crash risk increases 50% with untreated OSA. The process of diagnosing and treating OSA in commercial drivers begins with effective and consistent screening. Therefore, the researchers screened drivers with both the STOP-Bang Questionnaire and the Obstructive Sleep Apnea Evaluation Worksheet (OSAEW) and compared the two tools...
April 1, 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28413816/spectroscopic-and-afm-characterization-of-polypeptide-surface-interactions-controls-and-lipid-quantitative-analyses
#3
Øyvind Strømland, Ørjan S Handegård, Morten L Govasli, Hanzhen Wen, Samuel Furse, Øyvind Halskau
This article is related to http://dx.doi.org/10.1016/j.bbamem.2017.01.005 (Ø. Strømland, Ø.S. Handegård, M.L. Govasli, H. Wen, Ø. Halskau, 2017) [1]. In protein and polypeptide-membrane interaction studies, negatively charged lipids are often used as they are a known driver for membrane interaction. When using fluorescence spectroscopy and CD as indicators of polypeptide binding and conformational change, respectively, the effect of zwitterionic lipids only should be documented. The present data documents several aspects of how two engineered polypeptides (A-Cage-C and A-Lnk-C) derived from the membrane associating protein alpha-Lactalbumin affects and are affected by the presence of zwitterionic bilayers in the form of vesicles...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28409526/the-impact-of-coat-protein-mediated-virus-resistance-in-applied-plant-pathology-and-basic-research
#4
John A Lindbo, Bryce W Falk
Worldwide, plant viruses cause serious reductions in marketable crop yield and in some cases even plant death. In most cases, the most effective way to control virus diseases is through genetically controlled resistance. However, developing virus-resistant (VR) crops through traditional breeding can take many years, and in some cases is not even possible. Because of this, the demonstration of the first VR transgenic plants in 1985 generated much attention. This seminal report served as an inflection point for research in both basic and applied plant pathology, the results of which have dramatically changed both basic research and in a few cases, commercial crop production...
April 14, 2017: Phytopathology
https://www.readbyqxmd.com/read/28408600/the-impact-of-hunting-on-tropical-mammal-and-bird-populations
#5
A Benítez-López, R Alkemade, A M Schipper, D J Ingram, P A Verweij, J A J Eikelboom, M A J Huijbregts
Hunting is a major driver of biodiversity loss, but a systematic large-scale estimate of hunting-induced defaunation is lacking. We synthesized 176 studies to quantify hunting-induced declines of mammal and bird populations across the tropics. Bird and mammal abundances declined by 58% (25 to 76%) and by 83% (72 to 90%) in hunted compared with unhunted areas. Bird and mammal populations were depleted within 7 and 40 kilometers from hunters' access points (roads and settlements). Additionally, hunting pressure was higher in areas with better accessibility to major towns where wild meat could be traded...
April 14, 2017: Science
https://www.readbyqxmd.com/read/28391092/survival-pattern-of-first-accident-among-commercial-drivers-in-the-greater-accra-region-of-ghana
#6
Salifu Nanga, Nii Afotey Odai, Anani Lotsi
In this study, the average accident risk of commercial drivers in the Greater Accra region of Ghana and its associated risks were examined based on a survey data collected using paper-based questionnaires from 204 commercial drivers from the Greater Accra Region of Ghana. The Cox Proportional Hazards Model was used for multivariate analysis while the Kaplan-Meier (KM) Model was used to study the survival patterns of the commercial drivers. The study revealed that the median survival time for an accident to happen is 2...
April 6, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28380210/safety-and-health-of-professional-drivers-who-drive-on-brazilian-highways
#7
Fernanda Veruska Narciso, Marco Túlio de Mello
Traffic accidents and resulting injuries and deaths have become a global epidemic. In Brazil, most professional drivers, especially truck drivers, face irregular working hours and can be awake for more than 18 hours/day, which reduces their performance and alertness. In this article, we discuss the laws related to Brazilian professional drivers and their current amendments (No. 12,619/2012 and No. 13,103/2015) in relation to working hours at the wheel and rest breaks, which are vital for the quality of life of drivers and society in general...
March 30, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28378157/adherence-and-persistence-across-antidepressant-therapeutic-classes-a-retrospective-claims-analysis-among-insured-us-patients-with-major-depressive-disorder-mdd
#8
Katelyn R Keyloun, Ryan N Hansen, Zsolt Hepp, Patrick Gillard, Michael E Thase, Emily Beth Devine
BACKGROUND: Adherence and persistence to therapy, or how well a patient follows provider directions on frequency and time to discontinuation of prescribed medications, is associated with positive health outcomes, including decreased healthcare costs and patient mortality. A clear literature gap exists assessing adherence and persistence to antidepressants (ADs) in the major depressive disorder (MDD) population at clinically relevant time points and at the therapeutic class level. OBJECTIVE: This study assessed adherence and persistence to specific ADs, therapeutic classes, and AD therapy overall at multiple time points among US individuals from commercial, Medicare supplemental, and Medicaid insurance plans...
April 4, 2017: CNS Drugs
https://www.readbyqxmd.com/read/28377205/molecular-testing-turnaround-time-for-non-small-cell-lung-cancer-in-routine-clinical%C3%A2-practice-confirms-feasibility-of-cap-iaslc-amp-guideline-recommendations-a-single-center-analysis
#9
Marcello DiStasio, Yigu Chen, Deepa Rangachari, Daniel B Costa, Yael K Heher, Paul A VanderLaan
INTRODUCTION: Molecular testing to identify targetable driver mutations is the standard of care for patients with advanced-stage non-small cell lung cancer. Recent guideline recommendations by the College of American Pathologists (CAP), International Association for the Study of Lung Cancer (IASLC), and Association for Molecular Pathology (AMP) established a benchmark turnaround time (TAT) target of 10 working days for results to be available to the treating oncologist and ≤ 3 days for specimens to arrive at a commercial testing laboratory if testing is not performed in-house...
March 14, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28368189/commercial-motor-vehicle-driving-performance-an-examination-of-attentional-resources-and-control-using-a-driving-simulator
#10
Benjamin McManus, Karen Heaton, Despina Stavrinos
Commercial motor vehicle (CMV) drivers often multitask when driving to increase travel efficiency and to increase alertness. Secondary tasks have been shown to impact CMV driving differentially, and attentional resources have been posited as a key factor. However, underlying mechanisms of secondary task engagement on attention and task performance have not been fully examined. Additionally, it is unknown if attentional control moderates these differential effects of secondary tasks and task performance. The current study aimed to examine decrements in driving performance from a resource-control theory by determining the specific relation between attentional resources and attentional control...
April 3, 2017: Journal of Experimental Psychology. Applied
https://www.readbyqxmd.com/read/28361394/financial-feasibility-of-end-user-designed-rainwater-harvesting-and-greywater-reuse-systems-for-high-water-use-households
#11
Edgar Ricardo Oviedo-Ocaña, Isabel Dominguez, Sarah Ward, Miryam Lizeth Rivera-Sanchez, Julian Mauricio Zaraza-Peña
Water availability pressures, competing end-uses and sewers at capacity are all drivers for change in urban water management. Rainwater harvesting (RWH) and greywater reuse (GWR) systems constitute alternatives to reduce drinking water usage and in the case of RWH, reduce roof runoff entering sewers. Despite the increasing popularity of installations in commercial buildings, RWH and GWR technologies at a household scale have proved less popular, across a range of global contexts. For systems designed from the top-down, this is often due to the lack of a favourable cost-benefit (where subsidies are unavailable), though few studies have focused on performing full capital and operational financial assessments, particularly in high water consumption households...
March 30, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28358910/size-age-and-habitat-determine-effectiveness-of-palau-s-marine-protected-areas
#12
Alan M Friedlander, Yimnang Golbuu, Enric Ballesteros, Jennifer E Caselle, Marine Gouezo, Dawnette Olsudong, Enric Sala
Palau has a rich heritage of conservation that has evolved from the traditional moratoria on fishing, or "bul", to more western Marine Protected Areas (MPAs), while still retaining elements of customary management and tenure. In 2003, the Palau Protected Areas Network (PAN) was created to conserve Palau's unique biodiversity and culture, and is the country's mechanism for achieving the goals of the Micronesia Challenge (MC), an initiative to conserve ≥30% of near-shore marine resources within the region by 2020...
2017: PloS One
https://www.readbyqxmd.com/read/28356173/management-of-obstructive-sleep-apnea-in-commercial-motor-vehicle-operators-recommendations-of-the-aasm-sleep-and-transportation-safety-awareness-task-force
#13
Indira Gurubhagavatula, Shannon Sullivan, Amy Meoli, Susheel Patil, Ryan Olson, Michael Berneking, Nathaniel F Watson
The American Academy of Sleep Medicine Sleep and Transportation Safety Awareness Task Force responded to the Federal Motor Carrier Safety Administration and Federal Railroad Administration Advance Notice of Proposed Rulemaking and request for public comments regarding the evaluation of safety-sensitive personnel for moderate-to-severe obstructive sleep apnea (OSA). The following document represents this response. The most salient points provided in our comments are that (1) moderate-to-severe OSA is common among commercial motor vehicle operators (CMVOs) and contributes to an increased risk of crashes; (2) objective screening methods are available and preferred for identifying at-risk drivers, with the most commonly used indicator being body mass index; (3) treatment in the form of continuous positive airway pressure (CPAP) is effective and reduces crashes; (4) CPAP is economically viable; (5) guidelines are available to assist medical examiners in determining whether CMVOs with moderate-to-severe OSA should continue to work without restrictions, with conditional certification, or be disqualified from operating commercial motor vehicles...
March 28, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28347357/prevalence-and-risk-factors-associated-with-female-anal-sex-in-the-context-of-hiv-aids-in-the-selected-districts-of-tanzania
#14
Elizabeth H Shayo, Akili A Kalinga, Kesheni P Senkoro, Judith Msovela, Erick J Mgina, Angela E Shija, Godlisten Materu, Stella P Kilima, Leonard E G Mboera, Julius J Massaga
BACKGROUND: Female anal sex is a receptive type of sexual practice among heterosexual couples where the penis is inserted into the anus of a female partner. In the Western world, a number of studies and interventions have been carried out on anal sex among men due to its potential risks to HIV transmission. In African countries, including Tanzania, there is dearth of information on the risks inherent in practices associated with female anal sex in the general population. The objective of this study was to determine the prevalence and risk factors associated with female anal sex in fuelling HIV transmission in selected districts of Tanzania...
March 27, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28345440/the-economic-burden-of-opioid-abuse-updated-findings
#15
Noam Y Kirson, Lauren M Scarpati, Caroline J Enloe, Aliya P Dincer, Howard G Birnbaum, Tracy J Mayne
BACKGROUND: Opioid pain relievers can be highly effective in providing relief for patients suffering from pain. At the same time, prescription opioid abuse, dependence, overdose, and poisoning (hereinafter "abuse") have become a national public health concern. Opioid abuse is also costly: previous estimates of the annual excess costs of opioid abuse to payers range from approximately $10,000 to $20,000 per patient. OBJECTIVES: To (a) provide a comprehensive, current estimate of the economic burden of opioid abuse to commercial payers and (b) explore the drivers of these excess costs of abuse...
April 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28341699/genomic-comparison-of-indigenous-african-and-northern-european-chickens-reveals-putative-mechanisms-of-stress-tolerance-related-to-environmental-selection-pressure
#16
Damarius S Fleming, Steffen Weigend, Henner Simianer, Annett Weigend, Max Rothschild, Carl Schmidt, Christopher Ashwell, Mike Persia, James Reecy, Susan J Lamont
Global climate change is increasing the magnitude of environmental stressors, such as temperature, pathogens, and drought that limit survivability and sustainability of livestock production. Poultry production and its expansion are dependent upon robust animals that are able to cope with stressors in multiple environments. Understanding the genetic strategies that indigenous, non-commercial breeds have evolved to survive in their environment could help to elucidate molecular mechanisms underlying biological traits of environmental adaptation...
March 24, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28335743/reasons-for-discontinuation-of-subcutaneous-interferon-%C3%AE-1a-three-times-a-week-among-patients-with-multiple-sclerosis-a-real-world-cohort-study
#17
Meritxell Sabidó-Espin, Rick Munschauer
BACKGROUND: Continuation of interferon (IFN) β-based therapies is important for maximum treatment effectiveness in patients with multiple sclerosis (MS); however, few real-world data are available on discontinuation from IFN β. The aim of this cohort analysis was to estimate real-world discontinuation rates up to 3 years among MS patients in the United States taking subcutaneous (sc) IFN β-1a three times a week (tiw) and to identify whether the factors associated with discontinuation change over time...
March 23, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28334313/colour-vision-requirements-in-visually-demanding-occupations
#18
J L Barbur, M Rodriguez-Carmona
Normal trichromatic colour vision (CV) is often required as a condition for employment in visually demanding occupations. If this requirement could be enforced using current, colour assessment tests, a significant percentage of subjects with anomalous, congenital trichromacy who can perform the suprathreshold, colour-related tasks encountered in many occupations with the same accuracy as normal trichromats would fail. These applicants would therefore be discriminated against unfairly. One solution to this problem is to produce minimum, justifiable CV requirements that are specific to each occupation...
March 18, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28332819/path-to-impact-for-autonomous-field-deployable-chemical-sensors-a-case-study-of-in-situ-nitrite-sensors
#19
Tim M Schierenbeck, Matthew C Smith
Natural freshwater systems have been severely affected by excess loading of macronutrients (e.g., nitrogen and phosphorus) from fertilizers, fossil fuels, and human and livestock waste. In the USA, impacts to drinking water quality, biogeochemical cycles, and aquatic ecosystems are estimated to cost US$210 billion annually. Field-deployable nutrient sensors (FDS) offer potential to support research and resource management efforts by acquiring higher resolution data than are currently supported by expensive conventional sampling methods...
April 11, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28323449/the-relative-importance-of-real-time-in-cab-and-external-feedback-in-managing-fatigue-in-real-world-commercial-transport-operations
#20
Michael Fitzharris, Sara Liu, Amanda N Stephens, Michael G Lenné
OBJECTIVE: Real-time driver monitoring systems represent a solution to address key behavioral risks as they occur, particularly distraction and fatigue. The efficacy of these systems in real-world settings is largely unknown. This paper has three objectives: 1) to document the incidence and duration of fatigue in real-world commercial truck driving operations, 2) to determine the reduction, if any, in the incidence of fatigue episodes associated with providing feedback, and 3) to tease apart the relative contribution of in-cab warnings from 24 monitoring and feedback to employers...
March 21, 2017: Traffic Injury Prevention
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