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15 lead EKG

David D McMANUS, Jo Woon Chong, Apurv Soni, Jane S Saczynski, Nada Esa, Craig Napolitano, Chad E Darling, Edward Boyer, Rochelle K Rosen, Kevin C Floyd, Ki H Chon
BACKGROUND: Atrial fibrillation (AF) is a common and dangerous rhythm abnormality. Smartphones are increasingly used for mobile health applications by older patients at risk for AF and may be useful for AF screening. OBJECTIVES: To test whether an enhanced smartphone app for AF detection can discriminate between sinus rhythm (SR), AF, premature atrial contractions (PACs), and premature ventricular contractions (PVCs). METHODS: We analyzed two hundred and nineteen 2-minute pulse recordings from 121 participants with AF (n = 98), PACs (n = 15), or PVCs (n = 15) using an iPhone 4S...
January 2016: Journal of Cardiovascular Electrophysiology
Tomas Novotny, Raymond Robert Bond, Irena Andrsova, Lumir Koc, Martina Sisakova, Dewar Darren Finlay, Daniel Guldenring, Jindrich Spinar, Marek Malik
BACKGROUND: The electrocardiogram (ECG) is the most commonly used diagnostic procedure for assessing the cardiovascular system. The aim of this study was to compare ECG diagnostic skill among fellows of cardiology and of other internal medicine specialties (non-cardiology fellows). METHODS: A total of 2900 ECG interpretations were collected. A set of 100 clinical 12-lead ECG tracings were selected and classified into 12 diagnostic categories. The ECGs were evaluated by 15 cardiology fellows and of 14 non-cardiology fellows...
November 2015: Journal of Electrocardiology
Niccolo' Maurizi, Iacopo Olivotto, Louise R A Olde Nordkamp, Katia Baldini, Carlo Fumagalli, Tom F Brouwer, Reinoud E Knops, Franco Cecchi
BACKGROUND: Subcutaneous implantable cardioverter-defibrillator (S-ICD) is a promising option for patients with hypertrophic cardiomyopathy (HCM). Patients with HCM can present markedly abnormal electrocardiograms (ECGs), and there are no data on what percentage of patients with HCM fail the prerequisite S-ICD vector screening. OBJECTIVE: The purpose of this study was to determine the failure rate of the prerequisite vector screening using 1 or 2 acceptable vectors stratified for risk profile for sudden cardiac death and predictors of failure...
February 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Nakkawee Saengklub, Vudhiporn Limprasutr, Suwanakiet Sawangkoon, Chollada Buranakarl, Robert L Hamlin, Anusak Kijtawornrat
Dronedarone is a class III antiarrhythmic that has been used for management of atrial fibrillation in humans, but limited information was found in dogs. The objective of this study was to determine the acute effects of escalating concentrations of dronedarone on electrocardiograms (ECG), hemodynamics and cardiac mechanics in healthy dogs. A total of 7 beagle dogs were anesthetized with isoflurane and instrumented to obtain lead II ECG, pressures at ascending aorta, right atrium, pulmonary artery and left ventricle, and left ventricular pressure-volume relationship...
February 2016: Journal of Veterinary Medical Science
Takahiro Takeuchi, Takeshi Tomita, Hiroki Kasai, Daisuke Kashiwagi, Koji Yoshie, Tomonori Yaguchi, Yasutaka Oguchi, Ayako Kozuka, Milan Gautam, Hirohiko Motoki, Ayako Okada, Yuji Shiba, Kazunori Aizawa, Atsushi Izawa, Yusuke Miyashita, Jun Koyama, Minoru Hongo, Uichi Ikeda
A 15-year-old asymptomatic male patient presented with an electrocardiographic abnormality and left ventricular (LV) dysfunction (left ventricle ejection fraction of 40%) in a physical examination performed 2 years previously. LV dysfunction did not improve despite optimal medical therapy for dilated cardiomyopathy. Twelve-lead electrocardiography revealed a normal PR interval (138 ms) with a small delta-like wave in V2, but not a typical diagnostic wave that could be diagnosed as Wolff-Parkinson-White (WPW) syndrome by an electrocardiogram auto-analysis...
February 2015: Journal of Arrhythmia
Cecilia N Pisoni, Silvia Reina, Diego Arakaki, Alicia Eimon, Carolina Carrizo, Enri Borda
OBJECTIVES: Patients with systemic lupus erythematosus (SLE) and primary Sjögren's syndrome (pSS) have increased IL-1β levels. IL-1β and other pro-inflammatory cytokines have a modulating activity on cardiac ion channels and have been associated with increased arrhythmic risk in rheumatoid arthritis patients. Likewise, adult patients with connective tissue diseases (CTDs) may have prolonged QTc intervals associated with the presence of anti-Ro/SSA antibodies. Our objective was to evaluate the presence of serum IL-1β in subjects with CTDs, in relation to the presence of anti-Ro/SSA antibodies and QTc interval duration...
September 2015: Clinical and Experimental Rheumatology
Tom S Feng, Colby E Perkins, Lauren N Wood, Karyn S Eilber, Jerome K Wang, Catherine Bresee, Jennifer T Anger
PURPOSE: We identify areas of overuse and underuse in the preoperative evaluation of patients undergoing mid urethral sling surgery. We also estimate the effect of overuse of preoperative testing on health care costs. MATERIALS AND METHODS: We conducted a retrospective review of women who underwent sling surgery with or without concomitant prolapse repair between 2012 and 2013. Physician orders for preoperative electrocardiogram, chest x-ray, basic metabolic panel, complete blood count, coagulation studies and urinalysis were classified as appropriate or inappropriate based on summary guidelines from the American Academy of Family Physicians...
January 2016: Journal of Urology
Dariga U Akasheva, Ekaterina V Plokhova, Olga N Tkacheva, Irina D Strazhesko, Ekaterina N Dudinskaya, Anna S Kruglikova, Valentina S Pykhtina, Natalia V Brailova, Inna A Pokshubina, Natalia V Sharashkina, Mikhail V Agaltsov, Dmitry Skvortsov, Sergey A Boytsov
INTRODUCTION: With advancing age the left ventricle (LV) undergoes structural and functional changes, thereby creating the substrate for the development of diseases. One possible mechanism of the ageing heart is a cellular senescence. Leukocyte telomere length (LTL) is a marker of replicative ageing. The purpose of this study was to evaluate the structure and function of the LV in people of different ages free of cardiovascular diseases (CVD) and regular drug medication and to assess their relationship with LTL...
2015: PloS One
Candis Lee Kles, C Patrick Murrah, Kerry Smith, Elizabeth Baugus-Wellmeier, Terri Hurry, Cullen D Morris
BACKGROUND: Surgical site infections (SSI) increase morbidity and mortality, hospital costs, length of stay, readmissions, and risk of litigation and may impact a facility's reputation. METHODS: Through implementation of a Six Sigma, interdisciplinary team process and the Contextual Model for change engaged all stakeholders. A total of 44 perioperative processes were evaluated, with 15 processes ultimately altered. Revisions involved identifying inconsistent implementation of procedures and standardizing processes, as well as utilizing new suture techniques and products including disposable electrocardiogram leads and pacing wires, antibiotic-coated sutures, and silver-impregnated midsternal dressings...
September 2015: Dimensions of Critical Care Nursing: DCCN
Alexander C Perino, Muhammad Soofi, Nikhil Singh, Sonya Aggarwal, Victor Froelicher
BACKGROUND: We sought to characterize the prognostic value of the third universal definition of myocardial infarction (UDMI) and ≥40msec Q wave criteria. METHODS: We evaluated hazard ratios (HR) with 95% confidence intervals (CI) for cardiovascular (CV) death for computerized Q wave measurements from the electrocardiograms of 43,661 patients collected from 1987 to 1999 at the Palo Alto VA. There were 3929 (9.0%) CV deaths over a mean follow-up of 7.6 (±3.8) years...
September 2015: Journal of Electrocardiology
Jani Pirinen, Jukka Putaala, Aapo L Aro, Ida Surakka, Anita Haapaniemi, Markku Kaste, Elena Haapaniemi, Turgut Tatlisumak, Mika Lehto
BACKGROUND: The diagnostic work-up to reveal etiology in a young ischemic stroke (IS) patient includes evaluation for high-risk source of cardioembolism (HRCE), since this subtype associates with high early recurrence rate and mortality. We investigated the association of ECG findings with a final etiologic subgroup of HRCE in a cohort of young patients with first-ever IS. METHODS: The Helsinki Young Stroke Registry includes IS patients aged 15 to 49 years admitted between 1994 and 2007...
November 1, 2015: International Journal of Cardiology
Borje Darpo, Christine Garnett, James Keirns, Norman Stockbridge
Exposure-response (ER) analysis has evolved as an important tool to evaluate the effect of a drug on cardiac repolarization, as reflected in the QTc interval. It has been suggested that careful electrocardiogram (ECG) evaluation in 'first-in-human' studies using ER analysis could replace or serve as an alternative to the E14 'thorough QT' study. This commentary shares and discusses the results of a recently conducted study with the objective to evaluate this approach. Six drugs with a well-characterized QT effect, five of which are known QT prolongers, were evaluated in a study design similar to a conventional single-ascending-dose study...
September 2015: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
Marianne Delville, Laurent Sabbah, Delphine Girard, Caroline Elie, Sandra Manceau, Marie Piketty, Frank Martinez, Arnaud Méjean, Christophe Legendre, Rebecca Sberro-Soussan
INTRODUCTION: Cardiovascular disease is the leading cause of mortality after renal transplantation. The purpose of this study was to analyze cardiovascular risk factors at transplantation, occurrence of cardiovascular events in the first year after transplantation and evaluate pre-transplant work-up. MATERIAL AND METHOD: In total, 244 renal transplant recipients older than 50 years were included. The results of pre-transplant work-up, including clinical evaluation, electrocardiogram, echocardiography, myocardial perfusion testing and coronary angiography were analyzed...
2015: PloS One
Wei Ma, Fengmin Lu, Dongyan Wu, Bingwei Chen, Hongliang Cong, Reginald Liew, Jing Xu
BACKGROUND: The aim of this study was to describe the electrocardiogram (ECG) morphology and electroanatomical characteristics of counterclockwise tricuspid annular atrial flutter (CCWTA-AFL) in the patients with prior atriotomy. METHODS AND RESULTS: This retrospective study included 34 patients with CCWTA-AFL after cardiac surgery and 20 patients with typical CCWTA-AFL without prior surgery. For patients in the post-surgical group, 19 had single-loop CCWTA-AFL and 15 had a double loop CCWTA-AFL...
May 29, 2015: Journal of Cardiovascular Electrophysiology
Rienzi Díaz, Jorge Vega, Helmuth Goecke
We report a 74-year-old man with diabetes mellitus type 2 and hypertension, who recently underwent coronary bypass surgery due to severe triple vessel disease receiving cardiological and combined antidiabetic therapy, including metformin 4 g/day. He was admitted with abdominal pain, nausea, vomiting, diarrhea and loss of consciousness. At admission, he was disoriented and agitated with signs of poor perfusion. His blood pressure was 80/70 mmHg, pulse rate 40 beats/min, respiratory rate 20-breaths/min, and axillary temperature 35 °C...
March 2015: Revista Médica de Chile
Gulten Tacoy, Mehmet Kadri Akboga, Cagri Yayla, Ahmet Akyel, Sedat Turkoglu, Murat Ozdemir, Ridvan Yalcin
BACKGROUND AND AIM: The aim of this study was to evaluate the effect of statin treatment on P-wave morphology, dispersion, and tissue Doppler imaging-derived atrial conduction time (PA-TDI), which are known to be predictors of atrial fibrillation (AF). METHODS: A total of 132 patients with guideline-directed statin indications but no clinical atrial tachyarrhythmias were studied. P-wave duration, P-wave dispersion, and P-wave amplitude on surface 12-lead electrocardiogram and PA-TDI were evaluated before and after three months of statin (either atrovastatin 10-40 mg/d or rosuvastatin 10-20 mg/d) treatment...
2015: Kardiologia Polska
Afshan B Hameed, Elizabeth S Lawton, Christy L McCain, Christine H Morton, Connie Mitchell, Elliott K Main, Elyse Foster
OBJECTIVE: Maternal mortality rates rose markedly from 2002 to 2006 in California, prompting an in-depth maternal mortality review in a state that comprises one twelfth of the US birth cohort. Cardiovascular disease has emerged as the leading cause of pregnancy-related death in the United States. The primary aim of this analysis was to describe the incidence and type of cardiovascular disease as a cause of pregnancy-related mortality in California. The secondary aims were to describe racial/ethnic and socioeconomic disparities, risk factors, birth outcomes, timing of death and diagnosis, and signs and symptoms of cardiovascular disease and identify contributing factors...
September 2015: American Journal of Obstetrics and Gynecology
Fengxiang Zhang, Bing Yang, Hongwu Chen, Weizhu Ju, Pipin Kojodjojo, Mingfang Li, Kai Gu, Gang Yang, Kejiang Cao, Minglong Chen
AIMS: To identify unique electrophysiological characteristics of pulmonary artery (PA) ventricular arrhythmias (VA) and determine long-term clinical outcomes following non-contact mapping (NCM)-guided ablation. METHODS AND RESULTS: The NCM array was deployed in consecutive patients undergoing clinically indicated ablation of outflow tract (OT) VA with left bundle branch block morphology, inferior axis and the precordial lead transition zone ≥ V3. Activation, pace and NCM mapping parameters, and electrocardiogram analysis of PA VA patients were compared with 50 patients with right ventricular OT (RVOT) or aortic coronary cusps (ACC) foci...
February 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Mahin Dianat, Negin Amini, Mohammad Badavi, Yaghoub Farbood
OBJECTIVE: In ventricular arrhythmias, due to their free radical scavenging action, antioxidant agents are usually used in the treatment of cardiovascular disease. Since stress is considered as risk factor for increased mortality by causing malignant arrhythmias, the study was designed to evaluate the cardioprotective effects of ellagic acid (EA) on CaCl2-induced arrhythmias in rat stress model. MATERIALS AND METHODS: Male Sprague-Dawley rats (200-250 g) were divided into four groups: Group I: Control rats (2 ml of saline by gavage), Group II: Rats treated with EA (15 mg/kg, gavage), Group III: stress group, Group IV: received EA plus stress...
March 2015: Avicenna Journal of Phytomedicine
Lingqiu Meng, Erika D Dunckley, Xiaolin Xu
OBJECTIVE: To explore the effects of levodopa on heart rate variability (HRV) in Parkinson's disease (PD). METHODS: A total of 48 PD patients (M:F = 35: 13, mean age: 59 ± 6 years, duration of illness: 4.7 ± 1.8 years, Hoehn & Yahr stage: 2.2 ± 0.3) on a stable dose of levodopa were recruited from January 2012 to May 2014.For confirming autonomic dysfunction, the baseline patient data (12 hours off-medication) were compared with a control group consisting of 48 age and gender-matched healthy subjects (M: F = 35: 13, mean age 58 ± 6 years)...
February 17, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
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