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https://www.readbyqxmd.com/read/29791012/a-systematic-mixed-studies-review-of-women-s-experiences-of-perineal-trauma-sustained-during-childbirth
#1
REVIEW
Rebecca Crookall, Gillian Fowler, Caroline Wood, Pauline Slade
AIM: To explore the quantitative/qualitative literature on women's experiences of perineal trauma sustained during childbirth and the impact it may have on psychological/emotional wellbeing BACKGROUND: Obstetric complications during childbirth can be a risk factor for postpartum psychological distress. Perineal trauma is one of the most frequent obstetric complications and it is important to understand any impact on psychological/emotional wellbeing. DESIGN: A convergent qualitative design using a hybrid deductive-inductive thematic synthesis approach to data transformation was used...
May 23, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29789019/adolescents-perceptions-and-experiences-of-pregnancy-in-refugee-and-migrant-communities-on-the-thailand-myanmar-border-a-qualitative-study
#2
Carine Asnong, Gracia Fellmeth, Emma Plugge, Nan San Wai, Mupawjay Pimanpanarak, Moo Kho Paw, Prakaykaew Charunwatthana, François Nosten, Rose McGready
BACKGROUND: Adolescent pregnancy remains a global health concern, contributing to 11% of all births worldwide and 23% of the overall burden of disease in girls aged 15-19 years. Premature motherhood can create a negative cycle of adverse health, economic and social outcomes for young women, their babies and families. Refugee and migrant adolescent girls might be particularly at risk due to poverty, poor education and health infrastructure, early marriage, limited access to contraception and traditional beliefs...
May 22, 2018: Reproductive Health
https://www.readbyqxmd.com/read/29777645/-childbirth-is-not-a-sickness-a-woman-should-struggle-to-give-birth-exploring-continuing-popularity-of-home-births-in-western-kenya
#3
Violet Naanyu, Joyce Baliddawa, Beatrice Koech, Julie Karfakis, Nancy Nyagoha
More than 95% of Kenyan women receive antenatal care (ANC) and only 62% access skilled delivery. To explore women's opinion on delivery location, 20 focus group discussions were conducted at an urban and rural setting in western Kenya. Participants included health care workers, traditional birth attendants (TBAs), and women who attended at least four ANC visits and delivered. Six in-depth interviews were also conducted with a combination of women who gave birth in a facility and at home. Discussions were digitally recorded and transcribed for analysis...
March 2018: African Journal of Reproductive Health
https://www.readbyqxmd.com/read/29773310/maternal-concentrations-of-human-chorionic-gonadotrophin-in-very-early-ivf-pregnancies-and-duration-of-pregnancy-a-follow-up-study
#4
Tom G Tanbo, Manuela Zucknick, Anne Eskild
RESEARCH QUESTION: Are maternal concentrations of human chorionic gonadotropin (HCG) on a fixed day after embryo transfer associated with duration of pregnancy? DESIGN: A follow-up study of 1917 singleton pregnancies after IVF was performed. Embryos were cultured for 2 days and maternal HCG concentration quantified on day 12 after embryo transfer. Duration of pregnancy was obtained from the Medical Birth Registry of Norway. Association of HCG concentration (log2-transformed) with duration of pregnancy was estimated as hazard ratios (HR) with 95% confidence intervals (CI) by applying Cox regression proportional hazard models, where time to delivery for pregnancies shortened because of planned Caesarean delivery or induction of labour was treated as censored...
May 2, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29769710/jdp2-overexpression-provokes-cardiac-dysfunction-in-mice
#5
Jacqueline Heger, Julia Bornbaum, Alona Würfel, Christian Hill, Nils Brockmann, Renáta Gáspár, János Pálóczi, Zoltán V Varga, Márta Sárközy, Péter Bencsik, Tamás Csont, Szilvia Török, Baktybek Kojonazarov, Ralph Theo Schermuly, Kerstin Böngler, Mariana Parahuleva, Peter Ferdinandy, Rainer Schulz, Gerhild Euler
The transcriptional regulator JDP2 (Jun dimerization protein 2) has been identified as a prognostic marker for patients to develop heart failure after myocardial infarction. We now performed in vivo studies on JDP2-overexpressing mice, to clarify the impact of JDP2 on heart failure progression. Therefore, during birth up to the age of 4 weeks cardiac-specific JDP2 overexpression was prevented by doxycycline feeding in transgenic mice. Then, JDP2 overexpression was started. Already after 1 week, cardiac function, determined by echocardiography, decreased which was also resembled on the cardiomyocyte level...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29768650/gestation-at-birth-mode-of-birth-infant-feeding-and-childhood-hospitalization-with-infection
#6
Jason P Bentley, David P Burgner, Antonia W Shand, Jane C Bell, Jessica E Miller, Natasha Nassar
INTRODUCTION: Infections are a leading cause of mortality and morbidity in preschool children. We aimed to assess the impact of the co-occurrence of cesarean section, early birth and formula feeding on hospitalization with infection in early childhood. MATERIAL AND METHODS: Population-based retrospective record-linkage cohort study of 488 603 singleton livebirths ≥32 weeks gestational age in New South Wales, Australia, 2007-2012. Multivariable Cox-regression was used to estimate independent and combined adjusted associations of gestational age, mode of birth (vaginal or cesarean section by labor onset) and formula feeding with time to first and repeat hospitalization with infection for children <5 years of age...
May 16, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29743106/the-foam-study-is-hysterosalpingo-foam-sonography-hyfosy-a-cost-effective-alternative-for-hysterosalpingography-hsg-in-assessing-tubal-patency-in-subfertile-women-study-protocol-for-a-randomized-controlled-trial
#7
Joukje van Rijswijk, Nienke van Welie, Kim Dreyer, Machiel H A van Hooff, Jan Peter de Bruin, Harold R Verhoeve, Femke Mol, Kimiko A Kleiman-Broeze, Maaike A F Traas, Guido J J M Muijsers, Arentje P Manger, Judith Gianotten, Cornelia H de Koning, Aafke M H Koning, Neriman Bayram, David P van der Ham, Francisca P J M Vrouenraets, Michaela Kalafusova, Bob I G van de Laar, Jeroen Kaijser, Miriam F van Oostwaard, Wouter J Meijer, Frank J M Broekmans, Olivier Valkenburg, Lucy F van der Voet, Jeroen van Disseldorp, Marieke J Lambers, Henrike E Peters, Marit C I Lier, Cornelis B Lambalk, Madelon van Wely, Patrick M M Bossuyt, Jaap Stoker, Fulco van der Veen, Ben W J Mol, Velja Mijatovic
BACKGROUND: Tubal pathology is a causative factor in 20% of subfertile couples. Traditionally, tubal testing during fertility work-up is performed by hysterosalpingography (HSG). Hysterosalpingo-foam sonography (HyFoSy) is a new technique that is thought to have comparable accuracy as HSG, while it is less expensive and more patient friendly. HyFoSy would be an acceptable alternative for HSG, provided it has similar effectiveness in terms of patient outcomes. METHODS/DESIGN: We aim to compare the effectiveness and costs of management guided by HyFoSy or by HSG...
May 9, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29741208/induction-of-labour-for-improving-birth-outcomes-for-women-at-or-beyond-term
#8
REVIEW
Philippa Middleton, Emily Shepherd, Caroline A Crowther
BACKGROUND: Beyond term, the risks of stillbirth or neonatal death increase. It is unclear whether a policy of labour induction can reduce these risks. This Cochrane review is an update of a review that was originally published in 2006 and subsequently updated in 2012 OBJECTIVES: To assess the effects of a policy of labour induction at or beyond term compared with a policy of awaiting spontaneous labour or until an indication for birth induction of labour is identified) on pregnancy outcomes for infant and mother...
May 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29740195/prenatal-counseling-and-parental-decision-making-following-a-fetal-diagnosis-of-trisomy-13-or-18
#9
Phoebe Winn, Krishna Acharya, Erika Peterson, Steven Leuthner
OBJECTIVES: To evaluate parental decisions following a prenatal diagnosis of trisomy 13 (T13) or trisomy 18 (T18), prenatal counseling received, and pregnancy outcomes. STUDY DESIGN: Single-center, retrospective cohort study of families with a prenatal diagnosis of T13 or T18 from 2000 to 2016. RESULTS: Out of 152 pregnancies, 55% were terminated. Twenty percent chose induction with palliative care, 20% chose expectant management, 2% chose full interventions, and 3% were lost to follow-up...
May 8, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29739262/comparison-of-prostaglandin-and-mechanical-cervical-ripening-in-the-setting-of-small-for-gestational-age-neonates
#10
Robert M Rossi, Carri R Warshak, Heather R Masters, Jodi K Regan, Sara A Kritzer, Kristin P Magner
OBJECTIVE: To determine whether cervical ripening with misoprostol (MP) is associated with higher rates of cesarean delivery (CD) (CD) compared to dinoprostone (DP) or Pitocin/Foley balloon (PFB) in infants found to be small for gestational age (SGA). STUDY DESIGN: Single center institution based cohort study of all inductions between 2008-2012 where birth weight was found to be as SGA (< 10th percentile). Maternal demographic, obstetric, and labor characteristics were compared between SGA births where cervical ripening with MP, Mode compares MP to referent group (DP), or PFB was used as the primary agent...
May 8, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29734128/obstetric-and-perinatal-health-outcomes-related-to-schizophrenia-a-national-register-based-follow-up-study-among-finnish-women-born-between-1965-and-1980-and-their-offspring
#11
Laura Simoila, Erkki Isometsä, Mika Gissler, Jaana Suvisaari, Erja Halmesmäki, Nina Lindberg
BACKGROUND: This national register-based study assesses obstetric and perinatal health outcomes in women with schizophrenia and their offspring. METHODS: Using the Care Register for Health Care, we identified Finnish women who were born in 1965- 1980 and diagnosed with schizophrenia. For each case, five age- and place-of-birth- matched controls were obtained from the Central Population Register of Finland. They were followed from the day when the disorder was diagnosed in specialized health-care (the index day) until 31...
May 4, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29723130/trefoil-factor-3-in-perinatal-pancreas-is-increased-by-gestational-low-protein-diet-and-associated-with-accelerated-%C3%AE-cell-maturation
#12
Louise Winkel, Annika Bagge, Louise Larsen, Tobias N Haase, Morten Rasmussen, Jeanette Lykke, Dennis B Holmgaard, Lars Thim, Jens H Nielsen, Louise T Dalgaard
The endocrine pancreas expands markedly in the first postnatal days and the insulin producing β-cells initiate a functional maturation preceded by a morphological change of the islets of Langerhans. Trefoil factor 3 (TFF3) is a secreted peptide expressed in intestinal epithelia, where it promotes migration, but its role in the pancreas is not characterized. The aim of this study was to examine the expression and function of TFF3 in perinatal rat pancreas, ex vivo cultured fetal rat pancreas and in the rat β-cell line INS-1E...
May 3, 2018: Islets
https://www.readbyqxmd.com/read/29720015/outcomes-of-vacuum-assisted-vaginal-deliveries-of-mothers-with-gestational-diabetes-mellitus
#13
Dana Vitner, Liran Hiersch, Eran Ashwal, Daniel Nassie, Yariv Yogev, Amir Aviram
OBJECTIVE: To evaluate the outcomes of vacuum-assisted vaginal deliveries (VAD) among neonates of mothers with gestational diabetes mellitus (GDM). STUDY DESIGN: Retrospective cohort study of women with singleton gestation ≥37 + 0 weeks of gestation who underwent VAD at a single, tertiary, medical center (2007-2014). Women with GDM and their neonates were compared to women without diabetes and their neonates. Composite neonatal outcome was defined as ≥1 of the following: shoulder dystocia, 5-min Apgar score <7, asphyxia, seizure, subgaleal, subarachnoid or subdural hemorrhage, fracture of the clavicle, humerus or skull, or Erb's palsy...
May 2, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29719929/the-effect-of-parity-on-risk-of-complications-in-pregnant-women-with-epilepsy-a-population-based-cohort-study
#14
Kim C Danielsson, Ingrid Borthen, Nils E Gilhus, Nils H Morken
INTRODUCTION: Women with epilepsy have increased risk of complications in pregnancy with consequences for the mother and child. There are no studies on the influence of parity on complications in women with epilepsy. MATERIAL AND METHODS: This was a population-based cohort study of all first and second births in the Medical Birth Registry of Norway 1999-2013. Risks were estimated and complication rates were compared in distinct women with epilepsy treatment categories...
May 2, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29718540/obesity-gestational-diabetes-and-macrosomia-are-associated-with-increasing-rates-of-early-term-induction-of-labour-at-the-canberra-hospital
#15
Jonathan T McGuane, Lori Grlj, Michael J Peek
BACKGROUND: Early-term delivery is an important cause of short-term neonatal morbidity and associated high healthcare costs, with possible additional long-term developmental ramifications. As a form of 'iatrogenic' delivery, induction of labour (IOL) is a potentially modifiable contributor to this burden. AIMS: To determine patterns of, and primary indication for, early-term IOL, as well as temporal trends in this primary indication and differences from other modes of delivery with respect to maternal factors and maternal/neonatal outcomes...
May 2, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29696192/the-dual-trigger-study-rationale-and-study-design-of-a-prospective-double-blind-randomized-clinical-trial-comparing-pregnancy-rates-after-co-administration-of-low-dose-hcg-at-the-time-of-gnrh-agonist-trigger-or-35-h-later-for-the-prevention-of-ohss
#16
Daniel Griffin, Claudio Benadiva, Tara Budinetz, Carolina Sueldo, Andrea DiLuigi, John Nulsen, Lawrence Engmann
Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic complication of controlled ovarian stimulation. The use of gonadotropin releasing hormone (GnRH) agonist for the trigger of oocyte maturation is effective in the prevention of OHSS although it may result in a lower pregnancy rate. The use of adjuvant low dose human chorionic gonadotropin (hCG) at the time of trigger or at the time of oocyte retrieval may improve pregnancy rates. The goal of this dual trigger study is to evaluate the safety and efficacy of the use of low dose hCG administered at the time of GnRH agonist trigger or 35 h later as well as the potential impact on pregnancy rates...
December 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29687477/obstetric-interventions-trends-and-drivers-of-change-a-20-year-population-based-study-from-iceland
#17
Emma M Swift, Gunnar Tomasson, Helga Gottfreðsdóttir, Kristjana Einarsdóttir, Helga Zoega
BACKGROUND: Population data on obstetric interventions is often limited to cesarean delivery. We aimed to provide a more comprehensive overview of trends in use of several common obstetric interventions over the past 2 decades. METHODS: The study was based on nationwide data from the Icelandic Medical Birth Register. Incidence of labor induction, epidural analgesia, cesarean, and instrumental delivery was calculated for all births in 1995-2014. Change over time was expressed as relative risk (RR), using Poisson regression with 95% confidence intervals (CI) adjusted for several maternal and pregnancy-related characteristics...
April 24, 2018: Birth
https://www.readbyqxmd.com/read/29683307/maternity-care-update-labor-and-delivery
#18
Andrew Smith, Wendy B Barr, Erin Bassett-Novoa, Nicholas LeFevre
Labor is defined as contractions with cervical change and active labor starts when the cervix is dilated 6 cm. Updated labor curves and definitions should be used to define labor dystocia. Oxytocin and amniotomy have important roles in the management of labor dystocia. Structured intermittent fetal monitoring should be considered for women with low-risk pregnancies but continuous electronic fetal monitoring still is used most commonly. Moderate fetal heart rate variability is the most reliable marker of fetal well-being...
April 2018: FP Essentials
https://www.readbyqxmd.com/read/29681714/tamoxifen-is-better-than-low-dose-clomiphene-or-gonadotropins-in-women-with-thin-endometrium-7-mm-after-clomiphene-in-intrauterine-insemination-cycles-a-prospective-study
#19
Sunita Sharma, Geetha Rani, Gunja Bose, Indranil Saha, Sikha Bathwal, B N Chakravarty
Aim: Gonadotropin stimulation is used as the second line of treatment in patients with thin endometrium following clomiphene citrate (CC) administration, which is associated with higher cost, multiple births, and ovarian hyperstimulation syndrome. Tamoxifen (TMX), a selective estrogen receptor modulator, acts as an agonist on the endometrium. The objective of the present study was to compare the efficacy of low-dose CC, TMX, and gonadotropins in women with thin endometrium (<7 mm) following Clomiphene in intrauterine insemination (IUI) cycles...
January 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29680465/treatment-strategies-and-cumulative-live-birth-rates-in-who-ii-ovulation-disorders
#20
Sanne C Braam, Jan Peter de Bruin, Erato T I A Buisman, Monique Brandes, Willianne L D M Nelen, Jesper M J Smeenk, Jan Willem van der Steeg, Ben Willem J Mol, Carl J C M Hamilton
OBJECTIVE: To assess the live birth rate in women with WHO II anovulation and the proportion of women that need second or third line treatments if the initial therapy fails. STUDY DESIGN: In this multicenter cohort study we included couples with unfulfilled child wish who were referred to three fertility clinics in the Netherlands and selected women with a WHO II ovulation disorder as the only final infertility diagnosis (n = 468). RESULTS: The cumulative live birth rate of the total group was 82% (383/468)...
April 10, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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