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paraneoplastic cutaneous vasculitis

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https://www.readbyqxmd.com/read/27416971/systemic-paraneoplastic-vasculitis-secondary-to-papillary-carcinoma-of-the-thyroid
#1
N Guerouaz, M Alaoui, M Raiss, B Hassam, K Senouci
Systemic vasculitis secondary to thyroid carcinomas is exceptional. We report the case of a 55-year-old woman who presented with systemic vasculitis involving leucocytoclastic cutaneous vasculitis and renal disorders secondary to papillary thyroid carcinoma (PTC). Her symptoms resolved completely after total thyroidectomy. Other causes of vasculitis were excluded. To our knowledge, this is only the second case reported of systemic vasculitis associated with PTC in a paraneoplastic manner.
August 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27002952/leukocytoclastic-vasculitis-associated-with-hairy-cell-leukemia-at-diagnosis-a-case-report-and-review-of-the-literature
#2
Alessandro Broccoli, Letizia Gandolfi, Cinzia Pellegrini, Claudio Agostinelli, Lisa Argnani, Pier Luigi Zinzani
BACKGROUND: Autoimmune manifestations may occur in patients with hairy cell leukemia (HCL), and some rare cases of polyarteritis nodosa and leukocytoclastic vasculitis have been reported. However, data regarding the treatment of these cutaneous manifestations are lacking, given the rarity of the concomitance of HCL and vasculitic syndromes. CASE PRESENTATION: We present a 37-year-old man with paraneoplastic leukocytoclastic vasculitis complicating newly diagnosed HCL...
March 16, 2016: Tumori
https://www.readbyqxmd.com/read/26967709/sweet-s-syndrome-a-retrospective-study-of-90-cases-from-a-tertiary-care-center
#3
Meriem Amouri, Abdelrahmen Masmoudi, Morsi Ammar, Sonia Boudaya, Abdelmajid Khabir, Tahia Boudawara, Hamida Turki
BACKGROUND: Sweet's syndrome (SS) is a neutrophilic dermatosis characterized by the abrupt onset of cutaneous, systemic and histopathological alterations in response to different stimuli. OBJECTIVES: The aim of this study was to assess the epidemioclinical, histological, and therapeutic features and outcomes of SS. METHODS: A retrospective study of all patients diagnosed with SS over a 20-year period (1993-2012) was conducted. Data were analyzed using a level of significance of 5%...
September 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/25890241/dermatomyositis-as-the-first-manifestation-of-gallbladder-adenocarcinoma-case-report-and-literature-overview
#4
REVIEW
Petra Jurcic
Dermatomyositis (DM) is characterized by pathognomic cutaneous manifestations (heliotrope rash, periorbital edema, Gottron's papules) and proximal muscle weakness. In this paper, I will present the case of a 48-year-old female patient whose dermatomyositis was initially diagnosed as vasculitis. Following the patient's inadequate response to corticosteroid treatment, clinical and radiologic examinations were performed, showing inoperable gallbladder adenocarcinoma. Although initial chemotherapy led to regression, the dermatomyositis developed an independent course with new pathological changes leading to the progression of the disease...
2015: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/25843633/-leukocytoclastic-vasculitis
#5
Sergio Niklitschek, Sergio González, Cristián Vera-Kellet
No abstract text is available yet for this article.
September 7, 2015: Medicina Clínica
https://www.readbyqxmd.com/read/25544845/large-vessel-vasculitis-occurring-in-rheumatoid-arthritis-patient-under-anti-tnf-therapy
#6
Valentina Cestelli, Amelia Spinella, Federica Campomori, Carmela Esposito, Sara Ciaffi, Gilda Sandri, Clodoveo Ferri
Vasculitis is a heterogeneous group of disorders characterized by the presence of necrotic inflammatory phenomena and destruction of blood vessels. Vasculitis is classified as primary (idiopathic) or secondary to infections, connective tissue diseases and drugs but can also be considered as a paraneoplastic phenomenon. Evidence shows that the increasing use of biological agents results in a growing number of reports of autoimmune diseases induced by these therapies. An inflammatory articular chronic disease such as rheumatoid arthritis may be complicated by extra-articular manifestations, such as cutaneous or systemic vasculitis...
2014: Case Reports in Medicine
https://www.readbyqxmd.com/read/25374639/-paraneoplastic-cutaneous-vasculitis-revealing-non-hodgkin-s-lymphoma
#7
Wafa Chebbi, Baha Zantour
No abstract text is available yet for this article.
2014: Pan African Medical Journal
https://www.readbyqxmd.com/read/25106665/-auto-immune-diseases-and-cancers-second-part-auto-immune-diseases-complicating-cancers-and-their-treatment
#8
REVIEW
F Pasquet, M Pavic, J Ninet, A Hot
Autoimmune diseases may reveal or occur during the course of a neoplasia or its treatment. Autoimmune cytopenia, especially haemolytic anaemia, is common in lymphoproliferative disorders such as chronic lymphoid leukemia. The link between cancer and myositis is well established. Dermatomyositis is associated with an increased relative risk of cancer of 3.4 to 4.4. A combination of detection of antibodies against p155 and TEP-computed tomography may be the best approach to ascertain the presence of occult malignancy in patients with dermatomyositis...
October 2014: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/24975953/cancer-risk-in-dermatomyositis-a-systematic-review-of-the-literature
#9
REVIEW
D Di Rollo, D Abeni, M Tracanna, A Capo, P Amerio
The association between idiopathic inflammatory myopathy (IIM) and cancer has been extensively studied in adults. Many epidemiological studies demonstrated this association, which appears stronger for dermatomyositis (DM) than for polymyositis (PM). The first case suggesting an association between cancer and DM was reported in 1916. At present the reported incidence of cancer association with DM varies widely, from less than 7% to over 30%. Many early evidences came from case reports, but this association was later confirmed in case-control as well as in population-based studies...
October 2014: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/24912912/-hypereosinophilic-syndrome-as-paraneoplastic-presentation-in-an-adolescent
#10
Isabel Arias-Martínez, Marco Venancio-Hernández
Hypereosinophilic syndrome is characterized by peripheral eosinophilia over 1,500 cell/mm3 and/or tissue eosinophilia, with dysfunction or damage to organ, once other causes were ruled out. This paper presents a case of hypereosinophilic syndrome (HS) which presented as lymphoblastic leukemia in a teenager. This is a 13 year old female, with B cell lymphoblastic leukemia at 9 years old, who received chemotherapy for 2 years achieving remission. One year after remission she presented malar rash, hair loss, arthralgias, conjuntival redness, dyspnea and thoracic oppression...
October 2013: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/24145696/the-spectrum-of-paraneoplastic-cutaneous-vasculitis-in-a-defined-population-incidence-and-clinical-features
#11
Javier Loricera, Vanesa Calvo-Río, Francisco Ortiz-Sanjuán, Marcos A González-López, Hector Fernández-Llaca, Javier Rueda-Gotor, Maria C Gonzalez-Vela, Lino Alvarez, Cristina Mata, Domingo González-Lamuño, Victor M Martínez-Taboada, Miguel A González-Gay, Ricardo Blanco
Cutaneous vasculitis may be associated with malignancies, and may behave as a paraneoplastic syndrome. This association has been reported in a variable proportion of patients depending on population selection. We conducted the current study to assess the frequency, clinical features, treatment, and outcome of paraneoplastic vasculitis in a large unselected series of 766 patients with cutaneous vasculitis diagnosed at a single university hospital. Sixteen patients (10 men and 6 women; mean age ± standard deviation, 67...
November 2013: Medicine (Baltimore)
https://www.readbyqxmd.com/read/23943420/calcinosis-in-adult-onset-dermatomyositis-metastatic-or-dystrophic
#12
Barry Ladizinski, Ali Khan, Christopher Sankey
No abstract text is available yet for this article.
January 2014: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/23317981/cutaneous-manifestations-of-gastrointestinal-disease-part-ii
#13
REVIEW
Breck Thrash, Mahir Patel, Kejal R Shah, C Richard Boland, Alan Menter
The gastrointestinal (GI) and cutaneous organ systems are closely linked. In part I of this continuing medical education article, the intricacies of this relationship were explored as they pertained to hereditary polyposis disorders, hamartomatous disorders, and paraneoplastic disease. Part II focuses on the cutaneous system's links to inflammatory bowel disease and vascular disorders. An in-depth analysis of inflammatory bowel disease skin findings is provided to aid dermatologists in recognizing and facilitating early consultation and intervention by gastroenterologists...
February 2013: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/22919534/hypernephroma-presenting-with-cutaneous-leukocytoclastic-vasculitis-and-lupus-anticoagulant-resolution-after-nephrectomy
#14
Nigel P Murray, Amparo Ruíz, Eduardo Reyes
Hypernephroma can present as a variety of paraneoplastic, nonmetastatic conditions, including vasculitis, and rarely a lupus-type anticoagulant. Nephrectomy leads to the resolution of the systemic complaints. Malignancy, in this case hypernephroma, can present as an immune-mediated paraneoplastic syndrome which resolves after removal of the underlying tumor.
2012: Case Reports in Urology
https://www.readbyqxmd.com/read/22870466/malignancy-risk-in-vasculitis
#15
Tanaz A Kermani, Kenneth J Warrington, Shreyasee Amin
The vasculitides encompass a rare subset of autoimmune diseases. Reports of the concurrent association of malignancies with some forms of vasculitis raise the possibility that patients with certain types of vasculitis may be at increased risk of cancer. Conversely, some forms of vasculitis may be a manifestation of malignancy. We review cancer risk in patients with large vessel vasculitis (giant cell arteritis and Takayasu arteritis), polyarteritis nodosa, and the circulating antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitides...
February 2011: Therapeutic Advances in Musculoskeletal Disease
https://www.readbyqxmd.com/read/22821200/myelodysplasia-and-malignancy-associated-vasculitis
#16
REVIEW
Amir Agha, Helen Bateman, Ashley Sterrett, Joanne Valeriano-Marcet
While the link between malignancy and vasculitis has been known for some time, the association of vasculitis and myelodysplastic syndrome (MDS) has only recently been reported. This article reviews the most current and landmark publications regarding MDS, as well as malignancy-associated vasculitis. We include theories of paraneoplastic associations, immune pathogenesis including an associated cytokine transcriptional factor (interferon regulatory factor-1 [IFN-1]), and the relationship to treatment. Key clinical features that suggest underlying malignancy in patients with vasculitis are highlighted...
December 2012: Current Rheumatology Reports
https://www.readbyqxmd.com/read/22788803/clinical-features-diagnosis-and-treatment-of-erythema-multiforme-a-review-for-the-practicing-dermatologist
#17
REVIEW
Olayemi Sokumbi, David A Wetter
Erythema multiforme (EM) is an uncommon, immune-mediated disorder that presents with cutaneous or mucosal lesions or both. In herpes simplex virus (HSV)-associated EM, the findings are thought to result from cell-mediated immune reaction against viral antigen-positive cells that contain the HSV DNA polymerase gene (pol). The target lesion, with concentric zones of color change, represents the characteristic cutaneous finding seen in this disorder. Although EM can be induced by various factors, HSV infection continues to be the most common inciting factor...
August 2012: International Journal of Dermatology
https://www.readbyqxmd.com/read/22483523/cutaneous-granulomatous-vasculitis-associated-with-chronic-lymphocytic-leukemia-case-report-and-review-of-literature-of-a-rare-entity
#18
REVIEW
Erich M Gaertner, Stephen A Switlyk
Cutaneous granulomatous vasculitis associated with lymphoproliferative disorders is a rare entity, with only 14 cases previously reported in the English literature. Patients generally present with nodules or ulcers involving the extremities, which can appear months or years before or after onset of systemic disease. Granulomatous vasculitis has a poor prognosis when associated with underlying lymphoproliferative disorders, with the majority of reported cases fatal. Knowledge of this unusual entity is important to allow for proper clinical evaluation, follow-up, and therapy...
March 2012: Dermatology Online Journal
https://www.readbyqxmd.com/read/22197862/leukocytoclastic-vasculitis-as-early-manifestation-of-epstein-barr-virus-positive-diffuse-large-b-cell-lymphoma-of-the-elderly
#19
Pablo Zoroquiain, Sergio González, Montserrat Molgó, Alejandra Rodríguez, José R Valbuena
Extensive necrotizing vasculitis (ENV) is a rare paraneoplastic phenomenon, and the majority of cases reported are associated with hematolymphoid neoplasms. Histologically, most cases of ENV represent leukocytoclastic vasculitis (LCV). Here we report the clinicopahological features of a 68-year-old man with ENV associated to a Epstein Barr virus-positive diffuse large B-cell lymphoma (EBV+DLBCL) of the elderly, a newly recognized lymphoproliferative disorder, most likely representing a paraneoplastic manifestation...
May 2012: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/22035741/fatal-paraneoplastic-systemic-leukocytoclastic-vasculitis-as-a-presenting-feature-of-chronic-lymphocytic-leukemia
#20
Premal Lulla, Salman Bandeali, Kelty Baker
BACKGROUND: The most common paraneoplastic vasculitis is leukocytoclastic vasculitis (LCV),(1) 75% of which are caused by hematological malignancies. Chronic lymphocytic leukemia (CLL) is associated with a multitude of auto-immune paraneoplastic syndromes. Data on LCV in association with CLL is restricted to isolated case reports,(3,4) none of which had systemic LCV. We present a unique case of fatal paraneoplastic, systemic LCV as an initial presentation of CLL in an elderly male with multiple co-morbidities...
June 2011: Clinical Lymphoma, Myeloma & Leukemia
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