Michael Spicuzza, Shweta Prakesh Gaikwad, Steven Huss, Annemarie A Lee, Cristina V Craescu, Anna Griggs, Joshmi Joseph, Mark Puthenpurayil, Wilson Lin, Christopher Matarazzo, Stanley Baldwin, Victoria Perez, Diego Alejandro Rodriguez-Acevedo, John R Swierk, Elizabeth Elacqua
Macromolecular scaffolds are rapidly emerging in catalysis owing to the ability to control catalyst placement at precise locations. This spatial proximity allows for enhanced catalyst activity that may not be observed using small molecules. Herein, we describe a triphenylpyrylium (TPT)-based visible-light active single-chain polymer nanoparticle (SCNP) that facilitates the radical cation [4 + 2]-cycloaddition. We find that the catalytic activity is highly dependent on the styrylarene comonomer used, wherein it can act as a redox mediator under confinement, increasing the catalytic turnover (TON) by up to 30 times in comparison to free TPT in solution...
May 7, 2024: Polymer Chemistry