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https://www.readbyqxmd.com/read/28210204/physicochemical-properties-of-epoxy-resin-based-and-bioceramic-based-root-canal-sealers
#1
Ju Kyung Lee, Sang Won Kwak, Jung-Hong Ha, WooCheol Lee, Hyeon-Cheol Kim
Three bioceramic sealers (EndoSequence BC sealer, EndoSeal MTA, and MTA Fillapex) and three epoxy resin-based sealers (AH-Plus, AD Seal, and Radic-Sealer) were tested to evaluate the physicochemical properties: flow, final setting time, radiopacity, dimensional stability, and pH change. The one-way ANOVA and Tukey's post hoc test were used to analyze the data (P = 0.05). The MTA Fillapex sealer had a highest flow and the BC Sealer presented a flow significantly lower than the others (P < 0.05). The BC Sealer and MTA Fillapex samples were not set in humid incubator condition even after one month...
2017: Bioinorganic Chemistry and Applications
https://www.readbyqxmd.com/read/28199184/biphasic-organo-bioceramic-fibrous-composite-as-a-biomimetic-extracellular-matrix-for-bone-tissue-regeneration
#2
Sanjay Kumar, James A Stokes Iii, Derrick Dean, Christian Rogers, Elijah Nyairo, Vinoy Thomas, Manoj K Mishra
In bone tissue engineering, the organo-ceramic composite, electrospun polycaprolactone/hydroxyapatite (PCL/HA) scaffold has the potential to support cell proliferation, migration, differentiation, and homeostasis. Here, we report the effect of PCL/HA scaffold in tissue regeneration using human mesenchymal stem cells (hMSCs). We characterized the scaffold by fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), scanning electron microscope (SEM) and assessed its biocompatibility...
March 1, 2017: Frontiers in Bioscience (Elite Edition)
https://www.readbyqxmd.com/read/28194360/retreatability-of-two-endodontic-sealers-endosequence-bc-sealer-and-ah-plus-a-micro-computed-tomographic-comparison
#3
Enrique Oltra, Timothy C Cox, Matthew R LaCourse, James D Johnson, Avina Paranjpe
OBJECTIVES: Recently, bioceramic sealers like EndoSequence BC Sealer (BC Sealer) have been introduced and are being used in endodontic practice. However, this sealer has limited research related to its retreatability. Hence, the aim of this study was to evaluate the retreatability of two sealers, BC Sealer as compared with AH Plus using micro-computed tomographic (micro-CT) analysis. MATERIALS AND METHODS: Fifty-six extracted human maxillary incisors were instrumented and randomly divided into 4 groups of 14 teeth: 1A, gutta-percha, AH Plus retreated with chloroform; 1B, gutta-percha, AH Plus retreated without chloroform; 2A, gutta-percha, EndoSequence BC Sealer retreated with chloroform; 2B, gutta-percha, EndoSequence BC Sealer retreated without chloroform...
February 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/28183671/effect-of-phosphorus-precursors-on-the-structure-of-bioactive-calcium-phosphate-silicate-systems
#4
Katalin Sinkó, Anikó Meiszterics, János Rohonczy, Balázs Kobzi, Shiro Kubuki
The main aim of this work was to synthesize calcium phosphate silicate bioceramics by a low energy-consuming sol-gel method applying various phosphorous precursors (triethyl phosphate, phosphoric acid, and ammonium hydrogen phosphate). The investigations concentrated on the influence of phosphorous initial compounds on the bond and crystalline structures and the material quality. The application of the alkoxide and inorganic P-precursors results in considerably different textures. The inorganic PO4-containing precursors lead to sol formations...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183628/transdermal-delivery-of-insulin-with-bioceramic-composite-microneedles-fabricated-by-gelatin-and-hydroxyapatite
#5
Weijiang Yu, Guohua Jiang, Depeng Liu, Lei Li, Zaizai Tong, Juming Yao, Xiangdong Kong
The organic-inorganic bioceramic composite microneedles (MNs) were prepared from hydroxyapatite (Hap) and gelatin (Gel) via a template method. The resultant hydroxyapatite and gelatin composite MNs exhibited low cytotoxicity and excellent mechanical properties. After transdermal administration to the diabetic rats, the insulin could be released from bioceramic composite MNs. An obvious and effective hypoglycemic effect could be obtained compared with that of subcutaneous injection route. This work suggests that bioceramic composite MNs containing of insulin have a potential application in diabetes treatment via transdermal ingestion...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183587/mg-ca-ratio-as-regulating-factor-for-osteoclastic-in-vitro-resorption-of-struvite-biocements
#6
Carina Blum, Theresa Brückner, Andrea Ewald, Anita Ignatius, Uwe Gbureck
Bioceramic degradation can occur by both passive dissolution and following active osteoclastic bone remodeling. Key parameters controlling ceramic degradation are the pH-dependent solubility product of the ceramic phase, which alters ion concentrations in physiological solution and hence regulates cell activity. This study investigated the in vitro degradation profiles of various calcium magnesium phosphate ceramics formed at low temperature. The passive resorption was measured by incubating the cement samples in cell culture medium, while active resorption was determined during a surface culture of multinuclear osteoclastic cells derived from RAW 264...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28179924/fracture-resistance-of-roots-after-application-of-different-sealers
#7
Fatemeh Dibaji, Farzaneh Afkhami, Babak Bidkhori, Mohammad Javad Kharazifard
INTRODUCTION: Vertical root fracture inevitably leads to tooth extraction. Thus, root filling with obturating materials and sealers that can reinforce the tooth would be an ideal way to reduce fracture in root treated teeth. This study aimed to assess the fracture resistance of roots following the application of different sealers including Epiphany, iRoot sealer and AH-plus. METHODS AND MATERIALS: Fifty extracted human single-canal premolars without caries, curvature or cracks were used in this study...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28149466/effect-of-two-contemporary-root-canal-sealers-on-root-canal-dentin-microhardness
#8
Maram E Khallaf
BACKGROUND: Successful root canal treatment depends on proper cleaning, disinfecting and shaping of the root canal space. Pulpless teeth have lower dentin microhardness value compared to that of vital teeth. A material which can cause change in dentin composition may affect the microhardness. Thus the aim of this study was to evaluate and compare the effect of two root canal sealers on dentin microhardness. MATERIAL AND METHODS: Forty two single rooted teeth were selected and divided into 3 equal groups; Apexit, iRootSP and control groups (n=14) Each group was then divided into 2 subgroups according to the post evaluation period; 1 week and 2 months (n=7)...
January 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28135637/fabrication-and-characterization-of-baghdadite-nanostructured-scaffolds-by-space-holder-method
#9
Sorour Sadeghzade, Fateme Shamoradi, Rahmatollah Emadi, Fariborz Tavangarian
Porous baghdadite scaffold has received great attention as a candidate for bone tissue engineering application due to its remarkable bioactivity, biocompatibility, and good bone formation ability. A few studies have been focused on improving the mechanical properties of baghdadite scaffolds. Recently, space holder method has been introduced as a new and viable technique to prepare bioceramic scaffolds with interconnected pores and suitable mechanical properties. In this study, for the first time, 3D baghdadite scaffolds with interconnected porosity were produced using space holder method...
January 24, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28135032/rapid-vacuum-sintering-a-novel-technique-for-fabricating-fluorapatite-ceramic-scaffolds-for-bone-tissue-engineering
#10
Isabelle Denry, Ourania-Menti Goudouri, Jeffrey Harless, Julie A Holloway
Macroporous bioceramic scaffolds are often fabricated via the foam replica technique, based on polymeric foam impregnation with a glass slurry, followed by slow heat treatment to allow for drying, polymeric burnout, and sintering of the glass particles. As a consequence, the process is time consuming and complicated by concurrent crystallization of the glass, often leading to incomplete sintering. Our goal was to investigate the effect of heating rate on sintering behavior, architecture, and mechanical properties of fluorapatite-based glass and glass-ceramic scaffolds...
January 30, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28130134/nanoceramics-on-osteoblast-proliferation-and-differentiation-in-bone-tissue-engineering
#11
REVIEW
Sai Nievethitha S, Subhapradha N, Saravanan D, Selvamurugan N, Wei-Bor Tsai, Srinivasan N, Murugesan R, Moorthi A
Bone, a highly dynamic connective tissue, consist of a bioorganic phase comprising osteogenic cells and proteins which lies over an inorganic phase predominantly made of CaPO4 (biological apatite). Injury to bone can be due to mechanical, metabolic or inflammatory agents also owing pathological conditions like fractures, osteomyelitis, osteolysis or cysts may arise in enameloid, chondroid, cementum, or chondroid bone which forms the intermediate tissues of the body. Bone tissue engineering (BTE) applies bioactive scaffolds, host cells and osteogenic signals for restoring damaged or diseased tissues...
January 24, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28117976/3d-printed-bioactive-ca3sio5-bone-cement-scaffolds-with-nano-surface-structure-for-bone-regeneration
#12
Chen Yang, Xiaoya Wang, Bing Ma, Haibo Zhu, Zhiguang Huan, Nan Ma, Chengtie Wu, Jiang Chang
Silicate bioactive materials have received significant attention for application in bone regeneration due to their excellent physicochemical properties and outstanding osteogenic bioactivity, and different methods have been developed to prepare porous silicate bioactive ceramics scaffolds for bone tissue engineering applications. Among all these methods, 3D-printing technique is obviously the most efficient way to control the porous structure. However, 3D printed bioceramic porous scaffolds need high temperature sintering which will cause volume shrinkage and reduce the controllability of the pore structure accuracy...
January 24, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28106524/the-utility-of-3d-printing-for-surgical-planning-and-patient-specific-implant-design-for-complex-spinal-pathologies-case-report
#13
Ralph J Mobbs, Marc Coughlan, Robert Thompson, Chester E Sutterlin, Kevin Phan
OBJECTIVE There has been a recent renewed interest in the use and potential applications of 3D printing in the assistance of surgical planning and the development of personalized prostheses. There have been few reports on the use of 3D printing for implants designed to be used in complex spinal surgery. METHODS The authors report 2 cases in which 3D printing was used for surgical planning as a preoperative mold, and for a custom-designed titanium prosthesis: one patient with a C-1/C-2 chordoma who underwent tumor resection and vertebral reconstruction, and another patient with a custom-designed titanium anterior fusion cage for an unusual congenital spinal deformity...
January 20, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28106165/effects-of-sr-ht-gahnite-on-osteogenesis-and-angiogenesis-by-adipose-derived-stem-cells-for-critical-sized-calvarial-defect-repair
#14
Guifang Wang, Seyed-Iman Roohani-Esfahani, Wenjie Zhang, Kaige Lv, Guangzheng Yang, Xun Ding, Derong Zou, Daxiang Cui, Hala Zreiqat, Xinquan Jiang
Tissue engineering strategies to construct vascularized bone grafts are now attracting much attention. Strontium-hardystonite-Gahnite (Sr-HT-Gahnite) is a strong, highly porous, and biocompatible calcium silicate based bio-ceramic that contains strontium and zinc ions. Adipose derived stem cells (ASCs) have been demonstrated to have the ability in promoting osteogenesis and angiogenesis. In this study, the effects of Sr-HT-Gahnite on cell morphology, cell proliferation, and osteogenic differentiation of ASCs were systematically investigated...
January 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28056710/three-dimensional-printing-of-porous-load-bearing-bioceramic-scaffolds
#15
Elena Mancuso, Naif Alharbi, Oana A Bretcanu, Martyn Marshall, Mark A Birch, Andrew W McCaskie, Kenneth W Dalgarno
This article reports on the use of the binder jetting three-dimensional printing process combined with sintering to process bioceramic materials to form micro- and macroporous three-dimensional structures. Three different glass-ceramic formulations, apatite-wollastonite and two silicate-based glasses, have been processed using this route to create porous structures which have Young's modulus equivalent to cortical bone and average bending strengths in the range 24-36 MPa. It is demonstrated that a range of macroporous geometries can be created with accuracies of ±0...
December 1, 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28056168/conformational-changes-and-competitive-adsorption-between-serum-albumin-and-hemoglobin-on-bioceramic-substrate
#16
Cristina Gruian, Christian Rickert, Sascha Nicklisch, Emilia Vanea, Heinz-Jürgen Steinhoff, Simion Simon
Traditional methods to analyze interactions and conformational changes of proteins adsorbed onto biomaterials are limited by the protein's associations with the substrate material and the complexity of the surrounding media. We used EPR spectroscopy in combination with site directed spin labeling (SDSL) to investigate single protein and competitive adsorption kinetics of horse hemoglobin (Hgb) and bovine serum albumin (BSA) on a silica-calcium-phosphate bioceramic substrate. Combined continuous wave and pulsed (DEER) EPR techniques were employed to monitor local mobility/flexibility changes within the proteins and tertiary structure dynamics upon adsorption...
January 5, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28024584/a-comparative-study-on-the-synthesis-mechanism-bioactivity-and-mechanical-properties-of-three-silicate-bioceramics
#17
Aliakbar Najafinezhad, Majid Abdellahi, Hamid Ghayour, Ali Soheily, Akbar Chami, Amirsalar Khandan
In the present study three akermanite (Ca2MgSi2O7), diopside (CaMgSi2O6) and baghdadite (Ca3ZrSi2O9) applicable bioceramics were synthesized via a sol-gel based method. The combination of sol-gel method and the raw materials used in this study presents a new route for the synthesis of the mentioned bioceramics. By the use of thermal analysis, the mechanisms occurred during the synthesis of these bioceramics were investigated. The differences in the structural density and their relation with the degradation rate and mechanical properties of all three ceramics were studied...
March 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28012416/agarose-encapsulated-mesoporous-carbonated-hydroxyapatite-nanocomposites-powder-for-drug-delivery
#18
Elayaraja Kolanthai, P Abinaya Sindu, K Thanigai Arul, V Sarath Chandra, E Manikandan, S Narayana Kalkura
The powder composites are predominantly used for filling of voids in bone and as drug delivery carrier to prevent the infection or inflammatory reaction in the damaged tissues. The objective of this work was to study the synthesis of agarose encapsulation on carbonated hydroxyapatite powder and their biological and drug delivery properties. Mesoporous, nanosized carbonated hydroxyapatite/agarose (CHAp/agarose) powder composites were prepared by solvothermal method and subsequently calcined to study the physico-chemical changes, if it subjected to thermal exposure...
January 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/27987785/electrophoretic-deposition-of-silica-and-its-composite-coatings-on-ti-6al-4v-and-its-in-vitro-corrosion-behaviour-for-biomedical-applications
#19
M Chellappa, U Vijayalakshmi
Novel bioceramics have an intriguing role in implants and prostheses as surface protecting agents. These bioceramics have promising features such as biocompatible, bioactive, and corrosion-resistant natures. Among bioceramics, silica glass and its composite unravel its better desirability against corrosion and wear with interfacial bone bonding capability in physiological systems by nucleating calcium phosphates over the surface, thereby enhancing the osteoinductive property. In the current study, SiO2 and ZnO were obtained by processing silica and zinc oxide precursors at low temperature using low thermal volatilization sol-gel method...
February 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27987751/study-of-in-vitro-bioactivity-and-mechanical-properties-of-diopside-nano-bioceramic-synthesized-by-a-facile-method-using-eggshell-as-raw-material
#20
Amirhossein Kazemi, Majid Abdellahi, Armina Khajeh-Sharafabadi, Amirsalar Khandan, Neriman Ozada
In this study, diopside bioceramic was synthesized using a mechanical milling process and subsequent heat treatment. The simplicity of experiments and also the high energy available in ball milling lead to rapid synthesis of the products in comparison with other synthesis methods. Magnesium oxide (MgO), silicon dioxide (SiO2) and eggshell (as the calcium source) powders were weighted in stoichiometric conditions and milled to initial activation of the surface of the powder's mixture. Then a sintering process was conducted to complete formation of diopside nanopowder and also evaluates its thermal stability...
February 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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