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https://www.readbyqxmd.com/read/29029108/relative-risks-of-contributing-factors-to-morbidity-and-mortality-in-adults-with-craniopharyngioma-on-gh-replacement
#1
Kevin C J Yuen, Anders F Mattsson, Pia Burman, Eva-Marie Erfurth, Cecilia Camacho-Hubner, Janet L Fox, Johan Verhelst, Mitchell E Geffner, Roger Abs
Context: Craniopharyngioma (CP) in adults, of either childhood-onset (CO-CP) or adult-onset (AO-CP), is associated with increased morbidity and mortality, but data on the relative risks (RRs) of contributing factors are lacking. Objective: To assess the RRs of factors contributing to morbidity and mortality of adults with CO-CP and AO-CP. Methods: Data on 1,669 CP patients from KIMS (Pfizer International Metabolic Database) were analyzed using univariate and multiple Poisson and Cox regression methods...
September 29, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29028481/neuropsychiatric-symptoms-as-risk-factors-of-dementia-in-a-mexican-population-a-10-66-dementia-research-group-study
#2
Isaac Acosta, Guilherme Borges, Rebeca Aguirre-Hernandez, Ana Luisa Sosa, Martin Prince
INTRODUCTION: Cognitive and/or memory impairment are the main clinical markers currently used to identify subjects at risk of developing dementia. This study aimed to explore the relationship between the presence of neuropsychiatric symptoms and dementia incidence. METHODS: We analyzed the association between neuropsychiatric symptoms and incident dementia in a cohort of 1355 Mexican older adults from the general population over 3 years of follow-up, modeling cumulative incidence ratios using Poisson models...
October 10, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/29028442/the-use-of-mobile-applications-among-adults-with-type-1-and-type-2-diabetes-results-from-the-second-miles-australia-miles-2-study
#3
Steven Trawley, Shaira Baptista, Jessica L Browne, Frans Pouwer, Jane Speight
BACKGROUND: While the number of diabetes-specific mobile applications (apps) continues to grow, there is a lack of knowledge about their actual use. METHODS: The second MILES (Management and Impact for Long-term Empowerment and Success)-Australia study was a national cross-sectional survey of the psychological, behavioral, and social aspects of diabetes for adults with type 1 diabetes (T1D) and type 2 diabetes (T2D). Associations between diabetes-specific app usage and demographic, clinical, and psychosocial variables were examined...
October 13, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29027993/current-pharmacotherapy-for-obesity
#4
REVIEW
Gitanjali Srivastava, Caroline M Apovian
More than one-third of adults in the USA have obesity, which causes, exacerbates or adversely impacts numerous medical comorbidities, including diabetes mellitus and cardiovascular disease. Despite intensive lifestyle modifications, the disease severity warrants further aggressive intervention, including pharmacotherapy, medical devices and bariatric surgery. Noninvasive anti-obesity drugs have thus now resurfaced as targeted adjunctive therapeutic approaches to intensive lifestyle intervention, bridging the gap between lifestyle and bariatric surgery...
October 13, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/29027812/use-of-a-novel-remotely-connected-diabetes-management-system-is-associated-with-increased-treatment-satisfaction-reduced-diabetes-distress-and-improved-glycemic-control-in-individuals-with-insulin-treated-diabetes-first-results-from-the-personal-diabetes-management
#5
Pablo Mora, Ann Buskirk, Maureen Lyden, Christopher G Parkin, Lena Borsa, Bettina Petersen
BACKGROUND: The ability to automatically transfer data to clinicians and receive timely guidance in therapy adjustments through remote and in-office consults can positively impact patients' perceptions about quality of care, which is positively associated with clinical outcomes. We assessed the impact of using the Accu-Chek Connect diabetes management system on treatment satisfaction, diabetes distress, and glycemic control in adults with type 1 diabetes and insulin-treated type 2 diabetes...
October 13, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29026833/primary-prevention-of-cardiovascular-disease-in-older-adults-in-china
#6
REVIEW
Jian Yong, Dong Lin, Xue-Rui Tan
Over the past two decades, the percentage of Chinese who is 60 years or older has increased from 5.2% in 1995 to 10.5% in 2015. Approximately 16% of the population in China was 60 years old and above in 2015. Since 1990, cardiovascular disease (CVD) has been the leading cause of death in China. Cardiovascular medications of older adults are usually more complicated than younger age groups due to polypharmacy, the presence of comorbidities and more susceptible to treatment-related adverse outcomes. Therefore, effective primary prevention of CVD for older adults is important in sustaining the health of older adults and reducing the burden of the healthcare system...
September 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29026609/ketosis-prone-diabetes-and-sle-co-presenting-in-an-african-lady-with-previous-gestational-diabetes
#7
S Hussain, S Keat, S V Gelding
We describe the case of an African woman who was diagnosed with ketosis-prone diabetes with diabetes-associated autoantibodies, after being admitted for diabetic ketoacidosis (DKA) precipitated by her first presentation of systemic lupus erythematosus (SLE). She had a seven-year history of recurrent gestational diabetes (GDM) not requiring insulin therapy, with return to normoglycaemia after each pregnancy. This might have suggested that she had now developed type 2 diabetes (T2D). However, the diagnosis of SLE prompted testing for an autoimmune aetiology for the diabetes, and she was found to have a very high titre of GAD antibodies...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29026353/association-of-body-mass-index-and-postoperative-acute-kidney-injury-in-patients-undergoing-laparoscopic-surgery
#8
Maged Y Argalious, Natalya Makarova, Alexander Leone, Jacek Cywinski, Ehab Farag
BACKGROUND: Whether the deleterious effects of carbon dioxide pneumoperitoneum on the kidneys are exacerbated in the obese population remains unknown. We hypothesized that increased body mass index (BMI) is associated with an increased incidence of postoperative acute kidney injury (AKI) in patients undergoing noncardiac laparoscopic surgery. METHODS: Following institutional review board approval, we analyzed data on 8,543 adult patients with American Society of Anesthesiologists physical status scores of I-IV who had inpatient noncardiac laparoscopic surgery from 2005-2014...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29025840/a-county-level-cross-sectional-analysis-of-positive-deviance-to-assess-multiple-population-health-outcomes-in-indiana
#9
Michael Hendryx, Lucia Guerra-Reyes, Benjamin D Holland, Michael Dean McGinnis, Emily Meanwell, Susan E Middlestadt, Karen M Yoder
OBJECTIVE: To test a positive deviance method to identify counties that are performing better than statistical expectations on a set of population health indicators. DESIGN: Quantitative, cross-sectional county-level secondary analysis of risk variables and outcomes in Indiana. Data are analysed using multiple linear regression to identify counties performing better or worse than expected given traditional risk indicators, with a focus on 'positive deviants' or counties performing better than expected...
October 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/29025509/clinic-appointment-attendance-in-adults-with-serious-mental-illness-and-diabetes
#10
Douglas D Gunzler, Nathan Morris, Jarrod E Dalton, Richard McCormick, Neal V Dawson, Charles Thomas, Stephanie Kanuch, Kristin A Cassidy, Melanie Athey, Edna Fuentes-Casiano, Mary Ellen Lawless, Siobhan Martin, Douglas Einstadter, Martha Sajatovic
OBJECTIVES: We assessed characteristics that may predict outpatient appointment attendance in outpatient medical clinics among patients comorbid for serious mental illness (SMI) and type 2 diabetes (DM). METHODS: Baseline covariate data from 200 individuals with SMI-DM enrolled in a randomized controlled trial (RCT) were used to examine characteristics associated with electronic health record-identified clinic appointment attendance using a generalized estimating equations approach...
November 1, 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/29025457/characteristics-and-correlates-of-alcohol-consumption-among-adult-chronic-care-patients-in-north-west-province-south-africa
#11
Arvin Bhana, Sujit D Rathod, One Selohilwe, Tasneem Kathree, Inge Petersen
BACKGROUND: Alcohol consumption patterns in South Africa (SA) tend to be characterised by risky patterns of drinking. Taken together with the large burden of disease associated with HIV and tuberculosis (TB), heavy alcohol consumption patterns with these chronic conditions has the potential to compromise the efficacy of treatment efforts among such patients. OBJECTIVE: To explore the characteristics, correlates and diagnoses of alcohol use disorders among chronic care patients in SA...
June 30, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29025435/withania-somnifera-as-a-potential-candidate-to-ameliorate-high%C3%A2-fat-diet-induced-anxiety-and-neuroinflammation
#12
Taranjeet Kaur, Gurcharan Kaur
BACKGROUND: The epidemic of obesity has reached alarming levels in both developing and developed nations. Excessive calorie intake and sedentary lifestyle due to technological advancements are the main causal factors for overweight and obesity among the human population. Obesity has been associated with a number of co-morbidities such as hypertension, type 2 diabetes mellitus, cardiovascular diseases, and neurodegeneration and dementia. The progression of neurological disorders in obese subjects has been mainly attributed to neuroinflammation...
October 12, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29025270/design-of-a-randomized-clinical-trial-of-a-colorectal-cancer-screening-decision-aid-to-promote-appropriate-screening-in-community-dwelling-older-adults
#13
Christine E Kistler, Carol Golin, Carolyn Morris, Alexandra F Dalton, Russell P Harris, Rowena Dolor, Renée M Ferrari, Noel T Brewer, Carmen L Lewis
BACKGROUND: Appropriate colorectal cancer screening in older adults should be aligned with the likelihood of net benefit. In general, patient decision aids improve knowledge and values clarity, but in older adults, they may also help patients identify their individual likelihood of benefit and foster individualized decision-making. We report on the design of a randomized clinical trial to understand the effects of a patient decision aid on appropriate colorectal cancer screening. This report includes a description of the baseline characteristics of participants...
August 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/29024553/obesity-risk-factors-complications-and-strategies-for-sustainable-long-term-weight-management
#14
Sharon M Fruh
BACKGROUND AND PURPOSE: The aims of this article are to review the effects of obesity on health and well-being and the evidence indicating they can be ameliorated by weight loss, and consider weight-management strategies that may help patients achieve and maintain weight loss. METHODS: Narrative review based on literature searches of PubMed up to May 2016 with no date limits imposed. Search included terms such as "obesity," "overweight," "weight loss," "comorbidity," "diabetes," cardiovascular," "cancer," "depression," "management," and "intervention...
October 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/29023928/evaluation-of-medical-and-dental-visits-in-new-york-city-opportunities-to-identify-persons-with-and-at-risk-for-diabetes-mellitus-in-dental-settings
#15
Noreen Myers-Wright, Ira B Lamster, John P Jasek, Shadi Chamany
OBJECTIVE: The identification of persons with or at risk for chronic diseases is a new practice paradigm for oral healthcare. Diabetes mellitus (DM) is a chronic disease of particular importance to oral health providers. This study sought to understand healthcare utilization patterns that would support the introduction of this new practice paradigm. METHODS: The primary and oral healthcare utilization patterns of New York City (NYC) adults were assessed using data collected from the 2013 NYC Community Health Survey...
October 11, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/29023853/antibiotics-gut-microbiome-and-obesity
#16
Karen S W Leong, José G B Derraik, Paul L Hofman, Wayne S Cutfield
Antibiotics have been hailed by many as 'miracle drugs' that have been effectively treating infectious diseases for over a century, leading to a marked reduction in morbidity and mortality. However, with the increasing use of antibiotics, we are now faced not only with the increasing threat of antibiotic resistance, but also with a rising concern about potential long-term effects of antibiotics on human health, including the development of obesity. The obesity pandemic continues to increase, a problem that affects both adults and children alike...
October 12, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29023304/association-of-insulin-and-cholesterol-levels-with-peripheral-nervous-system-function-in-overweight-adults-a-3-year-follow-up
#17
Henri Isojärvi, Sirkka Keinänen-Kiukaanniemi, Mika Kallio, Kaisu Kaikkonen, Timo Jämsä, Juha Korpelainen, Raija Korpelainen
PURPOSE: The purpose of this prospective 3-year follow-up was to investigate the association of glucose, insulin, and cholesterol levels with peripheral nervous system function in overweight and obese subjects. METHODS: Forty nondiabetic overweight and obese adults were enrolled, of whom 29 completed the follow-up. Peripheral nervous system function was measured and defined by conduction studies of the peroneal motor nerve and the radial, sural, and medial plantar sensory nerves...
October 10, 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/29023255/adolescent-perceptions-of-peer-responses-to-diabetes-self-management-a-qualitative-study
#18
Pei-Yun Yang, Meei-Fang Lou, Angela Shin-Yu Lien, Bih-Shya Gau
BACKGROUND: Type 1 diabetes (T1D) is more prevalent in adolescents than in adults, and the self-management of insulin-dependent diabetes is complex. T1D requires injections of insulin, self-management of blood testing, regular physical activity, and diet monitoring, which are challenging for growing and developing adolescents. Adolescents are often more concerned with how they are perceived by their peers than how they perceive themselves. Positive peer responses influence the self-care management of adolescents with T1D in school settings...
October 12, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29023230/a-diabetic-retinopathy-screening-tool-for-low-income-adults-in-mexico
#19
Kenny Mendoza-Herrera, Amado D Quezada, Andrea Pedroza-Tobías, Cesar Hernández-Alcaraz, Jans Fromow-Guerra, Simón Barquera
INTRODUCTION: A national diabetic retinopathy screening program does not exist in Mexico as of 2017. Our objective was to develop a screening tool based on a predictive model for early detection of diabetic retinopathy in a low-income population. METHODS: We analyzed biochemical, clinical, anthropometric, and sociodemographic information from 1,000 adults with diabetes in low-income communities in Mexico (from 11,468 adults recruited in 2014-2016). A comprehensive ophthalmologic evaluation was performed...
October 12, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29023169/associations-of-physical-activity-and-sedentary-behaviour-with-vision-threatening-diabetic-retinopathy-in-indonesian-population-with-type-2-diabetes-mellitus-jogjakarta-eye-diabetic-study-in-the-community-joged-com
#20
D P Dharmastuti, A N Agni, F Widyaputri, S Pawiroranu, Z M Sofro, F S Wardhana, S Haryanto, T W Widayanti, S Kotha, P Gupta, M B Sasongko
PURPOSE: To investigate the association of physical activity (PA) and sedentary behaviour with diabetic retinopathy (DR) in type 2 diabetes adults. METHODS: A community-based cross-sectional study of adults with type 2 diabetes. DR was assessed from disc- and macula-centred fundus photograph, and categorised into mild, moderate non-proliferative DR (NPDR), and Vision-Threatening DR (VTDR). Worse eye was used to determine the person's DR severity. PA was assessed using WHO Global Physical Activity Questionnaire (GPAQ)...
October 12, 2017: Ophthalmic Epidemiology
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