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https://www.readbyqxmd.com/read/27936224/change-in-serum-bilirubin-level-as-a-predictor-of-incident-metabolic-syndrome
#1
You-Bin Lee, Seung-Eun Lee, Ji Eun Jun, Jae Hwan Jee, Ji Cheol Bae, Sang-Man Jin, Jae Hyeon Kim
AIM: Serum bilirubin level was negatively associated with the prevalence of metabolic syndrome (MetS) in previous cross-sectional studies. However, bilirubin variance preceding the development of MetS has yet to be investigated. We aimed to determine the effect of change in bilirubin concentration on the risk of incident MetS in healthy Korean adults. METHODS: We conducted a retrospective longitudinal study of subjects who had undergone at least four yearly health check-ups between 2006 and 2012...
2016: PloS One
https://www.readbyqxmd.com/read/27936096/factors-associated-with-disability-in-rural-bangladesh-bangladesh-population-based-diabetes-and-eye-study-bpdes
#2
Fakir M Amirul Islam, Jahar L Bhowmik, Silvia Z Islam, Andre M N Renzaho, Janet E Hiller
BACKGROUND: To assess factors associated with disability in a rural district of Bangladesh. METHODS: Using a population-based systematic sampling technique, data were collected from 3104 adults aged ≥ 30 years from the Banshgram union of Narail district. Data collected included an interviewer administered questionnaire to report physical disabilities including impairment that prevents engagement with paid work, visual, hearing, and mobility as well as mental disabilities...
2016: PloS One
https://www.readbyqxmd.com/read/27935988/effects-of-a-community-based-healthy-lifestyle-intervention-program-co-help-among-adults-with-prediabetes-in-a-developing-country-a-quasi-experimental-study
#3
Norliza Ibrahim, Foong Ming Moy, Intan Attikah Nur Awalludin, Zainudin Mohd Ali, Ikram Shah Ismail
BACKGROUND: The prevalence of type 2 diabetes among Malaysian adults has increased by more than two folds over the past two decades. Strategies to collaborate with the existing community partners may become a promising channel for wide-scale dissemination of diabetes prevention in the country. The objectives of this study were to determine the effects of community-based lifestyle interventions delivered to adults with prediabetes and their health-related quality of life as compared to the usual care group...
2016: PloS One
https://www.readbyqxmd.com/read/27935900/-thromboangiitis-obliterans-buerger-s-disease-state-of-the-art
#4
D D Zerbino, E A Zimba, N N Bagry
Thromboangiitis obliterans (Buerger's disease) is systemic vasculitis with predominant development of thrombotic occlusions of small-to-medium diameter arteries of distal portions of both upper and lower limbs. A distinctive feature of Buerger's disease from other vasculitides is the involvement of the venous bed into the pathological process in the form of migrating thrombophlebitis. The disease is encountered more often in young adult males, predominantly tobacco smokers. The clinical pattern is presented by symptoms of increasing insufficiency of blood supply of tissues of extremities...
2016: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/27935802/perceptions-on-diabetes-care-provision-among-health-providers-in-rural-tanzania-a-qualitative-study
#5
Mary Mwangome, Eveline Geubbels, Paul Klatser, Marjolein Dieleman
Diabetes prevalence in Tanzania was estimated at 9.1% in 2012 among adults aged 24-65 years - higher than the HIV prevalence in the general population at that time. Health systems in lower- and middle-income countries are not designed for chronic health care, yet the rising burden of non-communicable diseases such as diabetes demands chronic care services. To inform policies on diabetes care, we conducted a study on the health services in place to diagnose, treat and care for diabetes patients in rural Tanzania...
October 22, 2016: Health Policy and Planning
https://www.readbyqxmd.com/read/27935651/epidemiology-of-diabetic-kidney-disease-in-adult-patients-with-type-1-diabetes-in-italy-the-amd-annals-initiative
#6
Antonio Pacilli, Francesca Viazzi, Paola Fioretto, Carlo Giorda, Antonio Ceriello, Stefano Genovese, Giuseppina Russo, Pietro Guida, Roberto Pontremoli, Salvatore De Cosmo
BACKGROUND: Patients with type 1 diabetes mellitus are at increased risk of death. This risk appears to be modulated by kidney dysfunction. Aim of this study was to evaluate the prevalence of diabetic kidney disease (DKD), its traits and clinical correlates in a large sample of patients with type 1 diabetes. METHODS: Clinical data of 20,464 patients with type 1 diabetes were extracted from electronic medical records. Estimated glomerular filtration rate (eGFR) and increased urinary albumin excretion were considered...
December 9, 2016: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/27935392/sleep-disturbance-among-people-with-major-depressive-disorders-mdd-in-singapore
#7
Lee Seng Esmond Seow, Mythily Subramaniam, Edimansyah Abdin, Janhavi Ajit Vaingankar, Siow Ann Chong
BACKGROUND: Sleep problems are common with major depressive disorder (MDD), which has been identified as the most pervasive mental disorder in Singapore. AIMS: This study aimed to establish the prevalence of sleep disturbance among adults with lifetime and 12-month MDD, as well as its socio-demographic and clinical correlates. METHOD: Data were collected from the Singapore Mental Health Study, a cross-sectional epidemiological survey of the local residential population aged ≥18 years...
December 2016: Journal of Mental Health
https://www.readbyqxmd.com/read/27935240/effects-of-liraglutide-on-cardiovascular-risk-factors-in-patients-with-type-1-diabetes
#8
Thomas F Dejgaard, Nanna B Johansen, Christian S Frandsen, Ali Asmar, Lise Tarnow, Filip K Knop, Sten Madsbad, Henrik U Andersen
We investigated the short-term effect of adding liraglutide 1.8 mg once daily to insulin treatment on cardiovascular risk factors in patients with type 1 diabetes. In total, 100 overweight (BMI ≥25 kg/m(2) ) adult patients (age ≥18 years) with type 1 diabetes and HbA1c ≥8% (64 mmol/mol) were randomised to liraglutide 1.8 mg or placebo added to insulin treatment in a 24-week double-blinded, placebo-controlled trial. At baseline and after 24 weeks of treatment, 24-h blood pressure and heart rate, pulse pressure, pulse wave velocity, and carotid intima-media thickness were evaluated...
December 9, 2016: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/27935183/metformin-in-adults-with-type-1-diabetes-design-and-methods-of-reducing-with-metformin-vascular-adverse-lesions-removal-an-international-multicentre-trial
#9
J R Petrie, N Chaturvedi, I Ford, I Hramiak, A D Hughes, A J Jenkins, B Klein, R Klein, T C Ooi, P Rossing, N Sattar, C D A Stehouwer, H M Colhoun
INTRODUCTION: Cardiovascular (CV) disease is a major cause of reduced life expectancy in type 1 diabetes (T1D). Intensive insulin therapy prevents CV complications but is constrained by hypoglycaemia and weight gain. Adjunct metformin reduces insulin dose requirement and stabilises weight but there are no data on its cardiovascular effects. AIMS: We have initiated an international double-blind, randomized, placebo-controlled trial (REMOVAL: REducing with MetfOrmin Vascular Adverse Lesions in type 1 diabetes) to examine whether metformin reduces progression of atherosclerosis in adults with T1D...
December 9, 2016: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/27934649/safety-and-effectiveness-of-arginine-in-adults
#10
REVIEW
Catherine J McNeal, Cynthia J Meininger, Deepika Reddy, Colin D Wilborn, Guoyao Wu
l-Arginine (Arg) appears to have a beneficial effect on the regulation of nutrient metabolism to enhance lean tissue deposition and on insulin resistance in humans. The observed safe level for oral administration of Arg is ∼20 g/d, but higher levels have been tested in short-term studies without serious adverse effects; however, more data are needed in both animal models and humans to fully evaluate safety as well as efficacy. The primary objective of this review is to summarize the current knowledge of the safety, pharmacokinetics, and effectiveness of oral Arg in adults...
December 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27933750/comparing-glucose-and-hemoglobin-a1c-diagnostic-tests-among-a-high-metabolic-risk-hispanic-population
#11
Mónica A Vega-Vázquez, Margarita Ramirez-Vick, Francisco J Muñoz-Torres, Loida A González-Rodríguez, Kaumudi Joshipura
AIMS: Compare HbA1c diagnostic tests for pre-diabetes and diabetes with plasma glucose criteria (PGC), and compare the metabolic profiles of people classified by HbA1c versus by glucose levels. METHODS: Participants were recruited for the San Juan Overweight Adults Longitudinal Study (SOALS). Were primarily Hispanic (98%), without previously diagnosed diabetes, and aged 40-65 years. Participants classified as normal glycemic, pre-diabetes or diabetes based on baseline HbA1c and PGC, were compared with respect to baseline cardiometabolic factors...
December 9, 2016: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/27933635/vietnamese-version-of-diabetes-self-management-instrument-development-and-psychometric-testing
#12
Tiet-Hanh Dao-Tran, Debra J Anderson, Anne M Chang, Charrlotte Seib, Cameron Hurst
Self-management plays a vital role in diabetes management for adults with type 2 diabetes (T2DM). While there are many people with T2DM in Vietnam, clinical understanding of diabetes self-management (DSM) in this context is limited due to the lack of a valid measurement instrument. Translation and back-translation processes were used to translate the Diabetes Self-Management Instrument (DSMI) into Vietnamese. Then, translation equivalence, face validity, construct validity, and internal consistency were assessed in a sample of 198 Vietnamese adults with T2DM...
December 9, 2016: Research in Nursing & Health
https://www.readbyqxmd.com/read/27933514/changes-in-cardiac-repolarisation-during-spontaneous-nocturnal-hypoglycaemia-in-subjects-with-type-1-diabetes-a-preliminary-report
#13
Minna L Koivikko, Tuomas Kenttä, Pasi I Salmela, Heikki V Huikuri, Juha S Perkiömäki
AIMS: Experimental studies have revealed that hypoglycaemia can result in morphological changes in electrocardiographic repolarisation in subjects with type 1 diabetes. However, the influence of spontaneous nocturnal hypoglycaemia on repolarisation morphology in a 'real life' situation is not clear. METHODS: Adults with type 1 diabetes (n = 11) underwent continuous glucose monitoring with a subcutaneous sensor and digital 12-lead ECG recording for three nights...
December 8, 2016: Acta Diabetologica
https://www.readbyqxmd.com/read/27933415/association-between-gamma-glutamyltransferase-and-albuminuria-in-nondiabetic-adults-with-normal-renal-function
#14
Sun-Hye Ko, Myong Ki Baeg, Kyung-Do Han, Seung-Yeon Ko, Sae-Bom Shin, Seung-Hyun Ko, Yu-Bae Ahn
BACKGROUND: Serum gamma-glutamyltransferase (GGT) has been associated with albuminuria in diabetes patients, but it has not been investigated in the general population. We aimed to investigate the association between serum GGT and albuminuria in the nondiabetic Korean population with normal kidney function. METHODS: Study participants (3948; 1549 men and 2399 women) with an estimated glomerular filtration rate ≥60 mL/min/1.73 m(2) were analyzed from the fifth Korean National Health and Nutrition Examination Survey (2011)...
December 9, 2016: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/27933201/association-between-metabolic-syndrome-and-liver-histology-among-nafld-patients-without-diabetes
#15
Pushpjeet Kanwar, James E Nelson, Katherine Yates, David E Kleiner, Aynur Unalp-Arida, Kris V Kowdley
BACKGROUND: Metabolic syndrome (MetS) and obesity are associated with non-alcoholic fatty liver disease (NAFLD). The aim of this observational study was to examine the relationship of MetS and a diagnosis of non-alcoholic steatohepatitis (NASH) in patients without diabetes in the NASH Clinical Research Network (CRN). METHODS: Clinical, demographic, histological, laboratory and anthropometric data were collected on 356 adult patients without diabetes with NAFLD. Obesity was defined as body mass index ≥30...
2016: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/27933188/quality-of-care-in-rural-youth-with-type-1-diabetes-a-cross-sectional-pilot-assessment
#16
Kyle S Stumetz, Joyce P Yi-Frazier, Connor Mitrovich, Kathaleen Briggs Early
BACKGROUND: Type 1 diabetes mellitus (T1DM) presents a significant health burden for patients and families. The quality of care (QOC) among those living in rural communities is thought to be subpar compared with those in urban communities; however, little data exist to reflect this, especially in pediatric diabetes. OBJECTIVE: The purpose of this pilot study was to investigate diabetes QOC among families living in rural versus urban areas. 6 QOC markers were used to compare youth with T1DM: appointment adherence, patient-provider communication, diabetes education during clinic visit, congruency with diabetes standards of care, diabetes self-management behaviors, and diabetes-related hospitalizations...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27933187/validation-of-the-german-diabetes-risk-score-among-the-general-adult-population-findings-from-the-german-health-interview-and-examination-surveys
#17
Rebecca Paprott, Kristin Mühlenbruch, Gert B M Mensink, Silke Thiele, Matthias B Schulze, Christa Scheidt-Nave, Christin Heidemann
OBJECTIVE: To evaluate the German Diabetes Risk Score (GDRS) among the general adult German population for prediction of incident type 2 diabetes and detection of prevalent undiagnosed diabetes. METHODS: The longitudinal sample for prediction of incident diagnosed type 2 diabetes included 3625 persons who participated both in the examination survey in 1997-1999 and the examination survey in 2008-2011. Incident diagnosed type 2 diabetes was defined as first-time physician diagnosis or antidiabetic medication during 5 years of follow-up excluding potential incident type 1 and gestational diabetes...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27933186/effect-of-type-and-amount-of-dietary-carbohydrate-on-biomarkers-of-glucose-homeostasis-and-c-reactive-protein-in-overweight-or-obese-adults-results-from-the-omnicarb-trial
#18
Stephen P Juraschek, Edgar R Miller, Elizabeth Selvin, Vincent J Carey, Lawrence J Appel, Robert H Christenson, Frank M Sacks
OBJECTIVE: The glycemic index (GI) of dietary carbohydrate is thought to affect glucose homeostasis. Recently, the Effect of Amount and Type of Dietary Carbohydrates on Risk for Cardiovascular Heart Disease and Diabetes Study (OmniCarb) trial reported that a low-GI diet did not improve insulin sensitivity. We conducted this ancillary study of the OmniCarb trial to determine the effects of GI and carbohydrate content on glucose homeostasis and inflammation. RESEARCH DESIGN AND METHODS: OmniCarb was a randomized cross-over feeding study conducted in overweight or obese adults without diabetes (N=163)...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27932589/sex-and-race-ethnicity-differences-in-following-dietary-and-exercise-recommendations-for-u-s-representative-sample-of-adults-with-type-2-diabetes
#19
Joan A Vaccaro, Fatma G Huffman
This study examined sex by race/ethnicity differences in medical advice received for diet and exercise with corresponding health behaviors of a U.S. representative sample of adults with type 2 diabetes (N = 1,269). Data from the National Health and Nutrition Examination Surveys for 2011-2014 for 185 Mexican Americans, 123 Other Hispanics, 392 non-Hispanic Blacks, 140 non-Hispanic Asians, and 429 non-Hispanic Whites were analyzed using logistic regression analyses. Reporting being given dietary and exercise advice was positively associated with reporting following the behavior...
December 7, 2016: American Journal of Men's Health
https://www.readbyqxmd.com/read/27932133/metabolic-syndrome-after-liver-transplantation-five-year-prevalence-and-risk-factors
#20
F García-Pajares, I Peñas-Herrero, R Sánchez-Ocaña, R Torrres-Yuste, M Cimavilla-Román, A Carbajo-López, C Almohalla-Alvarez, B Pérez-Saborido, E Muñoz-Conejero, M Gonzalez-Sagrado, A Caro-Patón, G Sánchez-Antolín
Survival after orthotopic liver transplantation (OLT) has increased over the last decades, focusing on the metabolic complications that contribute to patient morbidity and mortality. The aim of our study was to describe the prevalence of metabolic syndrome (MS), its components, and its associated factors in patients who underwent OLT in a hospital in Spain. From November 2001 to January 2014, we performed 415 transplantations in 386 patients. We analyzed 204 patients with a minimum follow-up of 1 year (77.6% were male and the mean age was 54...
November 2016: Transplantation Proceedings
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