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lipidic emulsion

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https://www.readbyqxmd.com/read/28806986/antihyperlipidaemic-and-hepatoprotective-activities-of-acidic-and-enzymatic-hydrolysis-exopolysaccharides-from-pleurotus-eryngii-si-04
#1
Chen Zhang, Juan Li, Jing Wang, Xingling Song, Jianjun Zhang, Shang Wu, Chunlong Hu, Zhiyuan Gong, Le Jia
BACKGROUND: Hyperlipidaemia is the major risk factor contributing to the development and progression of atherosclerosis, fatty liver and cerebrovascular disease. Pleurotus eryngii (P. eryngii) is rich in biologically active components, especially polysaccharides that exhibit various biological activities, including reducing blood lipids. In the present study, three novel polysaccharide types, including exopolysaccharides (EPS), enzymatic EPS (EEPS) and acidic EPS (AEPS) were isolated, and the hypolipidaemic and hepatoprotective effects were investigated to better understand possible hypolipidaemic mechanisms and their hepatoprotective effects...
August 14, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28802007/characterization-of-intrinsic-material-properties-of-a-model-lipoproteic-emulsion-gel-by-oscillatory-and-creep-compliance-rheometry
#2
Kyle S Okada, Wan-Yuan Kuo, Youngsoo Lee
The effects of varying formulation and processing parameters on rheological properties in a model lipid/protein-based emulsion gel were studied. Heat-set model lipoproteic emulsion gels were prepared with varying levels of protein, lipid, and NaCl contents and high pressure homogenization treatments. Small deformation oscillatory rheometry, creep compliance, and pore size analysis experiments were used to characterize intrinsic structural properties, matrix interactions, and microstructure. Creep compliance behavior of the gel system was successfully modeled by a four-component Burgers model...
August 12, 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28797955/stability-and-assessment-of-amino-acids-in-parenteral-nutrition-solutions
#3
REVIEW
Nina Unger, Ulrike Holzgrabe
Sterile amino acid solutions are applied in medical care as part of Total Parenteral Nutrition systems. Typical formulations consist of variable admixtures of essential and non-essential amino acids together with carbohydrates, electrolytes, vitamins, trace element solutions and lipid emulsions. The complexity of these formulations gives rise to stability and compatibility reflections. This review focuses on amino acid stability in pure amino acid solution and name methods of assessment. Incompatibilities of amino acids with the other ingredients are matter of concern in clinical practice and evaluated for relevance...
August 2, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28794309/enteral-formula-containing-egg-yolk-lecithin-improves-diarrhea
#4
Tetsuro Akashi, Ayano Muto, Yayoi Takahashi, Hiroshi Nishiyama
Diarrhea often occurs during enteral nutrition. Recently, several reports showed that diarrhea improves by adding egg yolk lecithin, an emulsifier, in an enteral formula. Therefore, we evaluated if this combination could improve diarrhea outcomes. We retrospectively investigated the inhibitory effects on watery stools by replacing a polymeric fomula with that containing egg yolk lecithin. Then, we investigated the emulsion stability in vitro. Next, we examined the lipid absorption using different emulsifiers among bile duct-ligated rats and assessed whether egg yolk lecithin, medium-chain triglyceride, and dietary fiber can improve diarrhea outcomes in a rat model of short bowel syndrome...
August 8, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28793795/lipid-droplet-biogenesis
#5
Tobias C Walther, Jeeyun Chung, Robert V Farese
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo, converting cells to emulsions with LDs constituting the dispersed oil phase in the aqueous cytoplasm. Here we review our current view of LD biogenesis. We present a model of LD formation from the ER in distinct steps and highlight the biology of proteins that govern this biophysical process. Areas of incomplete knowledge are identified, as are connections with physiology and diseases linked to alterations in LD biology...
August 9, 2017: Annual Review of Cell and Developmental Biology
https://www.readbyqxmd.com/read/28792885/fish-oil-containing-lipid-emulsions-in-adult-parenteral-nutrition-a-review-of-the-evidence
#6
Osman Abbasoglu, Gil Hardy, William Manzanares, Alessandro Pontes-Arruda
BACKGROUND: There is evidence from laboratory and animal studies that fish oil-containing intravenous lipid emulsions (FOC-IVLEs) have a beneficial effect on inflammation and the immune response, suggesting a possible clinical benefit. Clinical studies of FOC-IVLEs have reported mixed results. The aim of this review is to present findings from recent randomized controlled clinical trials and other quality clinical studies investigating the effects of administering intravenous fish oil alone or as part of a multilipid emulsion and to examine the quality of these studies in an objective, evidence-based manner...
August 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28780417/purification-characterization-and-antioxidant-properties-of-a-novel-polysaccharide-extracted-from-sorghum-bicolor-l-seeds-in-sausage
#7
Sirine Ben Slima, Naourez Ktari, Imen Trabelsi, Hafedh Moussa, Iskandar Makni, Riadh Ben Salah
A novel polysaccharide named Sorghum Water-Soluble Polysaccharide (SWSP) was purified from Sorghum bicolor (L.) seeds. It was structurally characterized by high performance liquid chromatography (HPLC), thin layer chromatography (TLC), Fourier transform-infrared spectroscopy analysis (FT-IR), X-ray diffraction (XRD) and mass spectroscopy (MS). HPLC and TLC showed that SWSP is a glucose polymer. The FT-IR spectrum proved the polysaccharide characteristic band of SWSP. XRD and microscopy analyses revealed that SWSP is a semi-crystalline polymer...
August 3, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28776625/self-assembled-colloidal-complexes-of-polyphenol-gelatin-and-their-stabilizing-effects-on-emulsions
#8
Yu Huang, Aijun Li, Chaoying Qiu, YingLai Teng, Yong Wang
This research studies the in-depth characteristics including the binding interactions and morphological structure of tannic acid (TA)/grape seed proanthocyanidins (GSP) and gelatin (GLT) colloidal complexes, and evaluated the stability and lipid oxidation of emulsions formed by the colloidal complexes. Polyphenol and GLT (1.2 wt%) self-assembled complexes were fabricated by varying the mass ratio (1 : 16, 1 : 8 and 1 : 4) and pH in the range of 3-7. TA and GSP can form stable colloidal complexes with GLT at the nanoscale at pH 6, as shown by the particle size results, and the complexes exhibited a spherical morphology as seen by transmission electron microscopy...
August 4, 2017: Food & Function
https://www.readbyqxmd.com/read/28770989/a-microfluidic-technique-for-the-simultaneous-quantification-of-emulsion-instabilities-and-lipid-digestion-kinetics
#9
Nathalie Scheuble, Alexander Iles, Robert C R Wootton, Erich Josef Windhab, Peter Fischer, Katherine S Elvira
Quantifying the impact of environmental physicochemical changes on the micro-structure of lipid delivery systems is challenging. We have therefore developed a methodology to quantify the coalescence of oil-in-water emulsion droplets during lipid digestion in situ on a single droplet level. This technique involves a custom-made glass microfluidic platform, in which oil droplets can be trapped as single droplets, or several droplets per trap, the physicochemical environment can be controlled, and droplet digestion, as well as coalescence, can be visualized...
August 3, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28766181/treatment-of-amlodipine-intoxication-with-intravenous-lipid-emulsion-therapy-a-case-report-and-review-of-the-literature
#10
REVIEW
Funda Karbek Akarca, Ece Akceylan, Selahattin Kıyan
We report the case of a 25-year-old female presenting to the emergency department after committing suicide by ingesting 100 mg amlodipine. The patient was initially treated with intravenous fluids, calcium gluconate, catecholamines and glucagone without effect. The clinical condition of the patient improved quickly and dramatically on the 20th minute of intravenous lipid emulsion (ILE) therapy. Different treatment methods have been developed for calcium channel blocker intoxication over the last years. Among these, lipid emulsion therapy has risen over the last decade as a salvation in cases which do not respond to other treatments...
August 1, 2017: Cardiovascular Toxicology
https://www.readbyqxmd.com/read/28761828/formulation-of-menthol-loaded-nanostructured-lipid-carriers-to-enhance-its-antimicrobial-activity-for-food-preservation
#11
Parizad Piran, Hossein Samadi Kafil, Saeed Ghanbarzadeh, Rezvan Safdari, Hamed Hamishehkar
Purpose: Due to the antimicrobial property, menthol have significant potential for food preservation and foodstuff shelf life improvement. Nevertheless, menthol instability, insolubility, and rapid crystallization in aqueous media make it unsuitable for used in food products. This work was aimed to prepare menthol-loaded nanostructured lipid carriers (NLCs) to enhance its antimicrobial activity. Methods: Morphology, particle size and size distribution, encapsulation efficiency percent (EE%), and physical stability of the optimized formulation, prepared by hot melt homogenization method, were characterized by scanning electron microscopy, particle size analyzing, gas chromatography, and X-ray diffraction (XRD) methods...
June 2017: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28754085/regarding-a-comparison-of-fish-oil-sources-for-parenteral-lipid-emulsions-in-a-murine-model
#12
David F Driscoll
No abstract text is available yet for this article.
July 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28750167/comparison-of-antioxidant-evaluation-assays-for-investigating-antioxidative-activity-of-gallic-acid-and-its-alkyl-esters-in-different-food-matrices
#13
Natthaporn Phonsatta, Pawinee Deetae, Pairoj Luangpituksa, Claudia Grajeda-Iglesias, Maria Cruz Figueroa-Espinoza, Jérôme Le Comte, Pierre Villeneuve, Eric A Decker, Wonnop Visessanguan, Atikorn Panya
The addition of antioxidants is one of the strategies to inhibit lipid oxidation, a major cause of lipid deterioration in foods leading to rancidity development and nutritional losses. However, several studies have been reported that conventional antioxidant assays, e.g., TPC, ABTS, FRAP, and ORAC could not predict antioxidant performance in several foods. This study aimed to investigate the performance of two recently developed assays, e.g., the conjugated autoxidizable triene (CAT) and the apolar radical-initiated conjugated autoxidizable triene (ApoCAT) assays to predict the antioxidant effectiveness of gallic acid and its esters in selected food models in comparison with the conventional antioxidant assays...
August 15, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28747247/intravenous-fish-oil-in-critically-ill-and-surgical-patients-historical-remarks-and-critical-appraisal
#14
K Georg Kreymann, Daren K Heyland, Geraldine de Heer, Gunnar Elke
The purpose of this review is to explain the historical and clinical background for intravenous fish oil administration, to evaluate its results by using a product specific metaanalysis, and to stimulate further research in the immune-modulatory potential of fish oil. Concerning the immune-modulatory effects of fatty acids, a study revealed that ω-3 as well as ω-6 fatty acids would prolong transplant survival, and only a mixture with an ω-6:ω-3 ratio of 2.1:1 would give immune-neutral results. In 1998, the label of a newly registered fish oil emulsion also acknowledged this immune-neutral ratio in conjunction with ω-6 lipids...
July 13, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28742332/modulation-of-lipid-digestion-profiles-using-filled-egg-white-protein-microgels
#15
Luping Gu, Yujie Su, Zipei Zhang, Bingjing Zheng, Ruojie Zhang, David Julian McClements, Yanjun Yang
Colloidal delivery systems are required to encapsulate, protect, and release active food ingredients, such as vitamins, nutraceuticals, and minerals. In this study, lipid droplets were encapsulated within biopolymer microgels fabricated from egg white proteins using an injection-gelation process. Confocal fluorescence microscopy indicated that lipid droplets were dispersed within a network of cross-linked proteins within the microgels. The properties of the lipid-loaded microgels were compared to those of simple oil-in-water emulsions stabilized by egg white proteins...
August 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28741374/lipid-emulsion-alleviates-the-vasodilation-and-mean-blood-pressure-decrease-induced-by-a-toxic-dose-of-verapamil-in-isolated-rat-aortae-and-an-in-vivo-rat-model
#16
S-H Ok, I-W Shin, S H Lee, J Park, M S Woo, J-M Hong, J Kim, J-T Sohn
This study aimed to examine the effects of lipid emulsion on the vasodilation and cardiovascular depression induced by toxic doses of calcium channel blockers. The effects of lipid emulsion on the vasodilation induced by bepridil, verapamil, nifedipine, and diltiazem were investigated in isolated endothelium-denuded rat aortae. The effect of lipid emulsion on the comparable hemodynamic depression induced by the continuous infusion of a toxic dose of either verapamil or diltiazem was examined in an in vivo rat model...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28740349/functional-lipidomics-in-patients-on-home-parenteral-nutrition-effect-of-lipid-emulsions
#17
Loris Pironi, Mariacristina Guidetti, Ornella Verrastro, Claudia Iacona, Federica Agostini, Caterina Pazzeschi, Anna Simona Sasdelli, Michele Melchiorre, Carla Ferreri
AIM: To investigate the fatty acid-based functional lipidomics of patients on long-term home parenteral nutrition receiving different intravenous lipid emulsions. METHODS: A cross-sectional comparative study was carried out on 3 groups of adults on home parenteral nutrition (HPN), receiving an HPN admixture containing an olive-soybean oil-based intravenous lipid emulsion (IVLE) (OO-IVLE; n = 15), a soybean- medium-chain triacylglycerol-olive-fish oil-based IVLE (SMOF-IVLE; n = 8) or HPN without IVLE (No-IVLE; n = 8) and 42 healthy controls (HCs)...
July 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28738225/the-effect-of-low-fat-beef-patties-formulated-with-a-low-energy-fat-analogue-enriched-in-long-chain-polyunsaturated-fatty-acids-on-lipid-oxidation-and-sensory-attributes
#18
Marta Alejandre, Denis Passarini, Iciar Astiasarán, Diana Ansorena
A new low-energy gelled emulsion containing algae oil was developed as animal fat replacer. Its stability was evaluated under different storage conditions: 4V (4°C/vacuum), 4NV (4°C/no vacuum), 25V (25°C/vacuum) and 25NV (25°C/no vacuum). According to moisture, hardness, color and lipid oxidation data, 4°C under vacuum (4V) was selected as the best condition. Once the gelled emulsion was characterized, its effectiveness as fat analogue was demonstrated in beef patties. Reformulated patties were produced with 100% of animal fat replacement and compared to conventional patties (9%fat)...
July 13, 2017: Meat Science
https://www.readbyqxmd.com/read/28736984/randomized-double-blinded-placebo-controlled-pilot-study-on-the-effects-of-topical-blackcurrant-emulsion-enriched-in-essential-fatty-acids-ceramides-and-18-beta-glycyrrhetinic-acid-on-clinical-signs-and-skin-barrier-function-in-dogs-with-atopic-dermatitis
#19
Rosanna Marsella, Luisa Cornegliani, Ibrahim Ozmen, Mary Bohannon, Kim Ahrens, Domenico Santoro
BACKGROUND: Lipid-based emulsions can be useful for the management of canine atopic dermatitis (cAD). 18-beta glycyrrhetinic acid (GRA), a component of liquorice root, has anti-inflammatory and anti-pruritic effects. HYPOTHESIS/OBJECTIVES: To evaluate the effects of a topical lipid emulsion containing ceramides, fatty acids and GRA on clinical signs of cAD and skin barrier in a randomized, double-blinded, placebo-controlled trial. METHODS: Client owned (n = 45) dogs with nonseasonal, mild/moderate AD, received either treatment or placebo for three months...
July 23, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28734741/beneficial-effects-of-tqrf-and-tq-nano-and-conventional-emulsions-on-memory-deficit-lipid-peroxidation-total-antioxidant-status-antioxidants-genes-expression-and-soluble-a%C3%AE-levels-in-high-fat-cholesterol-diet-induced-rats
#20
Norsharina Ismail, Maznah Ismail, Nur Hanisah Azmi, Muhammad Firdaus Abu Bakar, Zhang Yida, Johnson Stanslas, Dahiru Sani, Hamidon Basri, Maizaton Atmadini Abdullah
The study determined the effect of thymoquinone rich fraction (TQRF) and thymoquinone (TQ) in the forms of nano- and conventional emulsions on learning and memory, lipid peroxidation, total antioxidant status, antioxidants genes expression and soluble β-amyloid (Aβ) levels in rats fed with a high fat-cholesterol diet (HFCD). The TQRF was extracted from Nigella sativa seeds using a supercritical fluid extraction system and prepared into nanoemulsion, which later named as TQRF nanoemulsion (TQRFNE). Meanwhile, TQ was acquired commercially and prepared into thymoquinone nanoemulsion (TQNE)...
July 20, 2017: Chemico-biological Interactions
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