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lipidic emulsion

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https://www.readbyqxmd.com/read/28917868/anti-hyperlipidemic-and-antioxidant-effects-of-alkali-extractable-mycelia-polysaccharides-by-pleurotus-eryngii-var-tuolensis
#1
Zhenzhen Ren, Juan Li, Nuo Xu, Jianjun Zhang, Xinling Song, Xiuxiu Wang, Zheng Gao, Huijuan Jing, Shangshang Li, Chen Zhang, Min Liu, Huajie Zhao, Le Jia
In this study, we noted that the Al-MPS from Pleurotus eryngii var. tuolensis provoked pharmacological effects on blood lipid profiles and oxidative stress. Animal studies demonstrated that Al-MPS showed potential effects on relieving hyperlipidemia and preventing oxidative stress, reflecting by decreasing the levels of serum enzyme activities (ALP, ALT and AST), restoring the activities of antioxidant enzymes (SOD, GSH-Px, CAT and T-AOC), down-regulating the MDA and LPO contents, as well as remitting the hepatic and cardiac tissues injury, respectively...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28917227/pharmacoeconomics-of-parenteral-nutrition-in-surgical-and-critically-ill-patients-receiving-structured-triglycerides-in-china
#2
Guo Hao Wu, Alexandra Ehm, Marco Bellone, Lorenzo Pradelli
BACKGROUND AND OBJECTIVES: A prior meta-analysis showed favorable metabolic effects of structured triglyceride (STG) lipid emulsions in surgical and critically ill patients compared with mixed medium-chain/long-chain triglycerides (MCT/LCT) emulsions. Limited data on clinical outcomes precluded pharmacoeconomic analysis. We performed an updated meta-analysis and developed a cost model to compare overall costs for STGs vs MCT/LCTs in Chinese hospitals. METHODS AND STUDY DESIGN: We searched Medline, Embase, Wanfang Data, the China Hospital Knowledge Database, and Google Scholar for clinical trials comparing STGs to mixed MCT/LCTs in surgical or critically ill adults published between October 10, 2013 and September 19, 2015...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28917061/use-of-lipid-emulsion-therapy-in-local-anesthetic-overdose
#3
Ozgur Karcioglu
The use of intravenous lipid emulsion (ILE) therapy as antidote in systemic toxicity of certain agents has gained widespread support. There are increasing data suggesting use of ILE in reversing from local anesthetic-induced systemic toxicity severe, life-threatening cardiotoxicity, although findings are contradictory. Efficiency of ILE was demonstrated in animal studies in the treatment of severe impairment of cardiac functions, via a mechanism for trapping lipophilic drugs in an expanded plasma lipid compartment ("lipid sink")...
October 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28915792/levosimendan-combined-with-epinephrine-improves-rescue-outcomes-in-a-rat-model-of-lipid-based-resuscitation-from-bupivacaine-induced-cardiac-arrest
#4
Fubei Nan, Xixi Cai, Yingchao Ye, Xuzhong Xu, Zhengqian Li, Min Li, Limei Chen
BACKGROUND: The effectiveness of a combination of a lipid emulsion with epinephrine in reversing local anesthetic-induced cardiac arrest has been confirmed. The combination of a lipid emulsion with levosimendan, was shown to be superior to administration of a lipid emulsion alone with regard to successful resuscitation. In this study, we compared the reversal effects of levosimendan, epinephrine, and a combination of the two agents in lipid-based resuscitation in a rat model of bupivacaine-induced cardiac arrest...
September 15, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28914056/effect-of-the-composition-and-structure-of-excipient-emulsion-on-the-bioaccessibility-of-pesticides-residue-in-agricultural-products
#5
Ruojie Zhang, Wenhao Wu, Zipei Zhang, Yeonhwa Park, Lili He, Baoshan Xing, David Julian McClements
The influence of co-ingestion of food emulsions with tomatoes on the bioaccessibility of a model pesticide (chlorpyrifos) was studied. Emulsions were fabricated with different oil contents (0 to 8%), lipid compositions (MCT and corn oil) and particle diameters (d32 = 0.17 and 10 μm). The emulsions were then mixed with chlorpyrifos-contaminated tomato puree, and the mixtures were subjected to a simulated gastrointestinal tract (GIT) consisting of mouth, stomach, and small intestine. The particle size, surface charge, and microstructure of the emulsions was measured as they passed through the GIT, and chlorpyrifos bioaccessibility was determined after digestion...
September 15, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28912919/intravenous-carnitine-administration-in-addition-to-parenteral-nutrition-with-lipid-emulsion-may-decrease-the-inflammatory-reaction-in-postoperative-surgical-patients
#6
Yu Koyama, Kazuki Moro, Masato Nakano, Kohei Miura, Masayuki Nagahashi, Shin-Ichi Kosugi, Junko Tsuchida, Mayuko Ikarashi, Masato Nakajima, Hiroshi Ichikawa, Takaaki Hanyu, Yoshifumi Shimada, Jun Sakata, Hitoshi Kameyama, Takashi Kobayashi, Toshifumi Wakai
BACKGROUND: A prospective randomized study was performed to investigate the validity of intravenous carnitine administration during postoperative parenteral nutrition (PN) with lipid emulsion. METHODS: Patients undergoing surgery for gastric or colorectal cancer were enrolled in the study and were randomly divided into two groups (n = 8 in each group): 1) group L, who received a peripheral PN (PPN) solution of 7.5% glucose, 30% amino acid, and 20% lipid emulsion; and 2) group LC, who received the same PPN solution, as well as carnitine intravenously...
October 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28895317/assessment-of-a-noninvasive-optical-photoplethysmography-imaging-device-with-dynamic-tissue-phantom-models
#7
C Ikenna Nwafor, Kevin D Plant, Darlene R King, Brian P McCall, John J Squiers, Wensheng Fan, J Michael DiMaio, Jeffrey E Thatcher
Noncontact photoplethysmography (PPG) has been studied as a method to provide low-cost, noninvasive, two-dimensional blood oxygenation measurements and medical imaging for a variety of near-surface pathologies. To evaluate this technology in a laboratory setting, dynamic tissue phantoms were developed with tunable parameters that mimic physiologic properties of the skin, including blood vessel volume change, pulse wave frequency, and tissue scattering and absorption. Tissue phantoms were generated using an elastic tubing to represent a blood vessel where the luminal volume could be modulated with a pulsatile fluid flow...
September 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28893413/fish-oil-emulsion-supplementation-might-improve-quality-of-life-of-diabetic-patients-due-to-its-antioxidant-and-anti-inflammatory-properties
#8
Lucia Laubertová, Katarína Koňariková, Helena Gbelcová, Zdeňka Ďuračková, Jana Muchová, Iveta Garaiova, Ingrid Žitňanová
Diabetes-related complications, including cardiovascular disease, retinopathy, nephropathy, and neuropathy, are a significant cause of increased morbidity and mortality among people with diabetes. Previous studies have confirmed that hyperglycemia has pro-oxidative and proinflammatory properties which cause diabetic complications. We hypothesized that supplementation of fish oil emulsion (FOE), rich in omega-3 polyunsaturated fatty acids, to diabetic patients might reduce hyperglycemia-induced pathological changes due to specific properties of FOE...
August 3, 2017: Nutrition Research
https://www.readbyqxmd.com/read/28888454/technological-characteristics-of-cold-set-gelled-double-emulsion-enriched-with-n-3-fatty-acids-effect-of-hydroxytyrosol-addition-and-chilling-storage
#9
María Freire, Ricard Bou, Susana Cofrades, Francisco Jiménez-Colmenero
A study was carried out to analyse the technological characteristics and microbiological content of gelled double emulsions (GDE) formulated with perilla oil (as lipid phase and source of n-3 fatty acids) combined or not with hydroxytyrosol (Hyt) (in the inner aqueous phase) over 30days storage at 4°C. Both the control sample without Hyt (GDE-C) and the sample containing Hyt (GDE-Hyt) had an appropriate whitish solid-like structure with rheological (elastic and viscous moduli, and phase angle) and textural (hardness and chewiness) properties of strong gels...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28888438/impact-of-legume-protein-type-and-location-on-lipid-oxidation-in-fish-oil-in-water-emulsions-lentil-pea-and-faba-bean-proteins
#10
Cansu Ekin Gumus, Eric Andrew Decker, David Julian McClements
Emulsion-based delivery systems are being developed to incorporate ω-3 fatty acids into functional foods and beverages. There is interest in formulating these delivery systems from more sustainable and label-friendly ingredients. The aim of this study was therefore to examine the impact of plant-protein emulsifiers on the oxidative stability of 1wt% fish oil-in-water emulsions. Fish oil emulsions stabilized by three types of legume protein (lentil, pea, and faba bean) were produced using a high-pressure microfluidizer...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28884566/effects-on-cognitive-function-of-propofol-medium-and-long-chain-lipid-emulsion-in-patients-with-hepatic-encephalopathy
#11
Shenghui Yu, Jianlei Hu, Li Ding, Da Yu
BACKGROUND: Our study aimed to investigate the effects of propofol medium and long chain lipid emulsion on cognitive function of the patients with hepatic encephalopathy undergoing hemofiltration treatment. METHODS: A total of 87 patients diagnosed with hepatic encephalopathy from January 2014 to January 2016 were continuously selected, and randomly (Using Random number method) divided into an observation group (45 cases) and a control group (42 cases). All patients were treated with persistent hemofiltration; the patients in control group were not given any sedative measures, while the patients in observation group were given a propofol medium-long chain lipid emulsion injection with a dose determined by each individual's degree of restlessness and tolerance to hemofiltration (Intravenous injection was performed with the first dose of 100mg, and then patients are subjected to micro-infusion pump with a dose of 0...
September 7, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28884420/relation-between-biophysical-properties-of-nanostructures-and-their-toxicity-on-zebrafish
#12
REVIEW
C S Martinez, D E Igartúa, M N Calienni, D A Feas, M Siri, J Montanari, N S Chiaramoni, S Del V Alonso, M J Prieto
In recent years, the use of commercial nanoparticles in different industry and health fields has increased exponentially. However, the uncontrolled application of nanoparticles might present a potential risk to the environment and health. Toxicity of these nanoparticles is usually evaluated by a fast screening assay in zebrafish (Danio rerio). The use of this vertebrate animal model has grown due to its small size, great adaptability, high fertilization rate and fast external development of transparent embryos...
September 7, 2017: Biophysical Reviews
https://www.readbyqxmd.com/read/28877036/recovery-from-ropivacaine-induced-or-levobupivacaine-induced-cardiac-arrest-in-rats-comparison-of-lipid-emulsion-effects
#13
Masashi Yoshimoto, Takashi Horiguchi, Tetsu Kimura, Toshiaki Nishikawa
BACKGROUND: Lipid emulsion treatment appears to have application in the treatment of local anesthetic-induced cardiac arrest. To examine whether the efficacy of lipid resuscitation in the treatment of local anesthetic-induced cardiac arrest is affected by lipophilicity, the effects of lipid infusions were compared between levobupivacaine-induced (high lipophilicity) and ropivacaine-induced (lower lipophilicity) rat cardiac arrest model. METHODS: A total of 28 female Sprague-Dawley rats were anesthetized using sevoflurane, which subsequently underwent tracheostomy, followed by femoral artery and vein cannulation...
September 2, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28876922/rheological-enhancement-of-pork-myofibrillar-protein-lipid-emulsion-composite-gels-via-glucose-oxidase-oxidation-transglutaminase-cross-linking-pathway
#14
Xu Wang, Youling L Xiong, Hiroaki Sato
Porcine myofibrillar protein (MP) was modified with glucose oxidase (GluOx)-iron that produces hydroxyl radicals then subjected to microbial transglutaminase (TGase) cross-linking in 0.6 M NaCl at 4 °C. The resulting aggregation and gel formation of MP were examined. The GluOx-mediated oxidation promoted the formation of both soluble and insoluble protein aggregates via disulfide bonds and occlusions of hydrophobic groups. The subsequent TGase treatment converted protein aggregates into highly cross-linked polymers...
September 18, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28873631/enhancing-physicochemical-properties-of-emulsions-by-heteroaggregation-of-oppositely-charged-lactoferrin-coated-lutein-droplets-and-whey-protein-isolate-coated-dha-droplets
#15
Xin Li, Xu Wang, Duoxia Xu, Yanping Cao, Shaojia Wang, Bei Wang, Baoguo Sun, Fang Yuan, Yanxiang Gao
The formation and physicochemical stability of mixed functional components (lutein & DHA) emulsions through heteroaggregation were studied. It was formed by controlled heteroaggregation of oppositely charged lutein and DHA droplets coated by cationic lactoferrin (LF) and anionic whey protein isolate (WPI), respectively. Heteroaggregation was induced by mixing the oppositely charged LF-lutein and WPI-DHA emulsions together at pH 6.0. Droplet size, zeta-potential, transmission-physical stability, microrheological behavior and microstructure of the heteroaggregates formed were measured as a function of LF-lutein to WPI-DHA droplet ratio...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28873574/creaming-and-oxidative-stability-of-fish-oil-in-water-emulsions-stabilized-by-whey-protein-xanthan-locust-bean-complexes-impact-of-ph
#16
Cory Owens, Kristen Griffin, Hanna Khouryieh, Kevin Williams
The impact of pH on the physicochemical properties of 10% menhaden oil-in-water (O/W) emulsions containing 2% whey protein isolate (WPI) and 0.1% xanthan (XG)-locust bean gum (LBG) mixtures was investigated. The O/W emulsions containing 0.1% XG-LBG mixtures were compared to emulsions with 0.1% XG and 0.1% LBG. The results indicated that stability is dependent on pH and biopolymer type. At both pH 3 and 5, emulsions containing either XG or XG-LBG mixtures had large particle sizes, viscosity, droplet aggregation, and creaming index, resulting in poor physical stability which can be related to the adsorbed protein-polysaccharide interactions...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28870158/erratum-to-lipid-emulsion-mitigates-impaired-pulmonary-function-induced-by-limb-i-r-in-rats-through-attenuation-of-local-cellular-injury-and-the-subsequent-systemic-inflammatory-response-inflammation
#17
Fangfang Xia, Yun Xia, Sisi Chen, Lulu Chen, Weijuan Zhu, Yuanqing Chen, Thomas J Papadimos, Xuzhong Xu, Le Liu
No abstract text is available yet for this article.
September 4, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28857206/development-and-validation-of-a-simple-high-performance-liquid-chromatography-analytical-method-for-simultaneous-determination-of-phytosterols-cholesterol-and-squalene-in-parenteral-lipid-emulsions
#18
Ana Novak, Mercè Gutiérrez-Zamora, Lluís Domenech, Josep M Suñé-Negre, Montserrat Miñarro, Encarna García-Montoya, Josep M Llop, Josep R Ticó, Pilar Pérez-Lozano
A simple analytical method for simultaneous determination of phytosterols, cholesterol, and squalene in lipid emulsions was developed due to increased interest in their clinical effects. Method development was based on commonly used stationary (C18 , C8 and phenyl) and mobile phases (mixtures of acetonitrile, methanol, and water) under isocratic conditions. Differences in stationary phases resulted in peak overlapping or coelution of different peaks. The best separation of all analyzed compounds was achieved on Zorbax Eclipse XDB C8 (150 x 4...
August 30, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28856220/frequency-and-causes-of-lipemia-interference-of-clinical-chemistry-laboratory-tests
#19
Sandhya Mainali, Scott R Davis, Matthew D Krasowski
OBJECTIVES: The aims of this study were to identify the causes of severe lipemia in an academic medical center patient population and to determine the relationship between lipemia and hemolysis. DESIGN AND METHODS: Retrospective study was done on the data from the core clinical laboratory at an academic medical center. Lipemic indices were available for all chemistry specimens analyzed over a 16-month period (n=552,029 specimens) and for serum/plasma triglycerides concentrations ordered for clinical purposes over a 16-year period (n=393,085 specimens)...
August 2017: Pract Lab Med
https://www.readbyqxmd.com/read/28855131/preparation-and-properties-of-multifunctional-sinapic-acid-corn-bran-arabinoxylan-esters
#20
Yanli Li, Tong He, Rong Liang, Zhengzhe Luo, Yuanbo Zhu, Cheng Yang
In the present study, corn bran arabinoxylan (CAX) were modified with sinapic acid (SA) by esterification to generate sinapic acid corn bran arabinoxylan esters (SA-CAX) with various substituted degrees. The structure of SA-CAX was characterized by FT-IR, NMR and UV spectroscopy. And the antioxidant activities of SA-CAX were evaluated by scavenging the 2,2'-diphenyl-1-picrylhydrazyl (DPPH) radical, emulsion lipid oxidation test and the lipid peroxidant level test. Compared with CAX, SA-CAX exhibited superior antioxidant activities in vitro, which indicated that the attachment of SA to CAX could enhance antioxidant activities of CAX...
August 27, 2017: International Journal of Biological Macromolecules
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