keyword
https://read.qxmd.com/read/38242034/elevated-18f-fdg-uptake-in-subcutaneous-adipose-tissue-correlates-negatively-with-nutritional-status-and-prognostic-survival-in-cachexia-patients-with-gastric-cancer
#1
JOURNAL ARTICLE
Diya Sun, Hongyan Yin, Xiao Liu, Zuoyou Ding, Lei Shen, Szechun Sah, Jun Han, Guohao Wu
BACKGROUND: Browning of white adipose tissue is a crucial factor contributing to adipose loss in cachexia patients, detectable via 18F-Fluorodeoxyglucose (18F-FDG) uptake. The present study elucidates the clinical relevance of 18F-FDG uptake in the subcutaneous adipose tissue of gastric cancer patients, specifically focusing on adipose browning and its implications on patient clinical parameters and prognosis. METHODS: This investigation encompassed 770 gastric cancer patients, with PET-CT imaging and clinical data meticulously combined...
February 2024: Clinical Nutrition
https://read.qxmd.com/read/38085297/endoscopic-negative-pressure-treatment-from-management-of-complications-to-pre-emptive-active-reflux-drainage-in-abdomino-thoracic-esophageal-resection-a%C3%A2-new-safety-concept-for-esophageal-surgery
#2
JOURNAL ARTICLE
Gunnar Loske, Johannes Müller, Wolfgang Schulze, Burkhard Riefel, Matthias Reeh, Christian Theodor Müller
INTRODUCTION: Early postoperative reflux (PR) can compromise anastomotic healing after Ivor Lewis esophagectomy (ILE) and poses a risk for aspiration. Anastomotic insufficiency is the most threatening surgical complication. We present the protective method of pre-emptive active reflux drainage (PARD) with simultaneous enteral feeding. We report our experience with this new safety concept in esophageal surgery in a cohort of 43 patients. MATERIALS AND METHODS: For PARD we use a double lumen open porous film drainage (dOFD)...
December 12, 2023: Chirurgie (Heidelb)
https://read.qxmd.com/read/37882839/-endoscopic-negative-pressure-treatment-from-management-of-complications-to-pre-emptive-active-reflux-drainage-in-abdominothoracic-esophageal-resection-a-new-safety-concept-for-esophageal-surgery
#3
JOURNAL ARTICLE
Gunnar Loske, Johannes Müller, Wolfgang Schulze, Burkhard Riefel, Matthias Reeh, Christian Theodor Müller
INTRODUCTION: Early postoperative reflux (PR) can compromise anastomotic healing after Ivor Lewis esophagectomy (ILE) and poses a risk for aspiration. Anastomotic insufficiency is the most threatening surgical complication. We present the protective method of pre-emptive active reflux drainage (PARD) with simultaneous enteral feeding. We report our experience with this new safety concept in esophageal surgery in a cohort of 43 patients. MATERIALS AND METHODS: For PARD we use a double lumen open porous film drainage (dOFD)...
October 26, 2023: Chirurgie (Heidelb)
https://read.qxmd.com/read/37578472/hyperpolarized-1-13-c-acetyl-l-carnitine-probes-tricarboxylic-acid-cycle-activity-in-vivo
#4
JOURNAL ARTICLE
Jun Chen, Tamara K Singh, Sarah Al Nemri, Maheen Zaidi, Kelvin L Billingsley, Jae Mo Park
Mitochondrial oxidative phosphorylation (OXPHOS) is sensitive to a variety of biological factors, and dysregulated OXPHOS is observed during the development of numerous pathological conditions. ATP production via OXPHOS is intrinsically dependent on the availability of acetyl-coenzyme A (CoA), which can enter the tricarboxylic acid (TCA) cycle to drive the oxidative pathway. Acetyl-l-carnitine (ALCAR) is an interchangeable endogenous source of acetyl-CoA, and therefore, ALCAR-derived probes are uniquely positioned for the assessment of OXPHOS...
August 14, 2023: ACS Sensors
https://read.qxmd.com/read/37563815/capparis-spinosa-promoted-bdnf-and-antioxidant-enzyme-levels-to-protect-against-learning-and-memory-deficits-induced-by-scopolamine
#5
JOURNAL ARTICLE
Mahmoud Hosseini, Fatemeh Mansouritorghabeh, Farimah Beheshti, Fatemeh Shahidpour, Fatemeh Forouzanfar, Arezoo Rajabian
BACKGROUND: Alzheimer's disease (AD) is a major neurodegenerative disorder with multiple manifestations, including oxidative stress, brain-derived neurotrophic factor (BDNF) depletion, and cholinergic dysfunction. Capparis spinosa (C. spinosa) is identified as a potential source of nutrition for alleviating various ailments. The current study assessed the ameliorating properties of C. spinosa hydroethanolic extract on memory dysfunction and the possible roles of oxidative stress and BDNF in the scopolamine (Scop)-treated rats...
August 9, 2023: Central Nervous System Agents in Medicinal Chemistry
https://read.qxmd.com/read/37549635/fluorescence-imaging-around-the-abdomen-allows-evaluation-of-gastrointestinal-retention-of-various-forms-of-diet-in-mice
#6
JOURNAL ARTICLE
Tomohiro Kagawa, Erika Mori, Ippei Yamaoka
OBJECTIVES: The aims of this study were to evaluate gastrointestinal (GI) retention of an ingested meal by fluorescence imaging and compare how retention is affected by differences in the physical characteristics of meals. METHODS: Mice were given an oral fluorescent indocyanine green (ICG) probe enclosed in a liposome. We evaluated the correlation between abdominal and GI fluorescence signals. ICG was administered to mice treated with atropine, and abdominal fluorescence was observed repeatedly...
July 12, 2023: Nutrition
https://read.qxmd.com/read/37233433/assessment-the-knowledge-care-and-experiences-of-neonatal-nurses-about-enteral-nutrition
#7
JOURNAL ARTICLE
N Ecem Oksal Gunes, Senay Cetinkaya
Enteral-feeding refers to any nutritional method throughout the gastrointestinal tract, including oral feeding. This qualitative study examined the information, experiences, and records of neonatal nurses of enterally fed patients. The study was conducted between 05.04.2018 and 05.05.2018 with 22 nurses (73.3%) working in the neonatal intensive care clinic of Çukurova University Balcali Hospital, Adana, Turkey. The data were collected by "Observation and Interview Form" developed based on the literature...
May 26, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/36249979/encapsulation-of-bougainvillea-bougainvillea-spectabilis-flower-extract-in-urtica-dioica-l-seed-gum-characterization-antioxidant-antimicrobial-properties-and-in-vitro-digestion
#8
JOURNAL ARTICLE
Reza Esmaeilzadeh Kenari, Razie Razavi
Bougainvillea spectabilis extract (BSE), a rich source of bioactive compounds like phenolic, flavonoid, and anthocyanin, was used for encapsulation with Urtica dioica L. seed gum. The extract was obtained using shaking, bath, and probe ultrasound. The results showed that probe ultrasound extract was more efficient, as reflected by the higher value of total phenolic (4354.15 mg GAE/100 g FW), flavonoid (2431.25 mg CE/100 g FW), and anthocyanin content (106.57 mg CGE/100 g FW). BSE was encapsulated in U...
October 2022: Food Science & Nutrition
https://read.qxmd.com/read/36094048/-evaluation-of-the-use-of-nasal-bridle-in-clinical-practice
#9
JOURNAL ARTICLE
Raquel Amalia Niddam Sánchez, Rosana Ashbaugh Enguídanos, Mario Bernal Álvarez, Julia Álvarez Hernández
INTRODUCTION: the nasal bridle (NB) is one of the strategies to avoid the displacement of tubes for enteral nutrition (EN) used during a nutritional intervention. OBJECTIVES: to review the efficacy and safety of NB placement in a patient population requiring EN by tube feeding. To analyze their clinical characteristics and identify complications related to this procedure. METHODS: a retrospective observational study in usual clinical practice including patients admitted to a second-level hospital with EN catheters who required the use of a commercial NB-CORGRIP NG/NI TFEEDING TUBE RETENTION SYSTEM...
September 5, 2022: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/35811959/case-report-morphologic-and-functional-characteristics-of-intestinal-mucosa-in-a-child-with-short-bowel-syndrome-after-treatment-with-teduglutide-evidence-in-favor-of-glp-2-analog-safety
#10
Enrico Costantino Falco, Antonella Lezo, Pierluigi Calvo, Caterina Rigazio, Anna Opramolla, Ludovica Verdun, Giovanna Cenacchi, Marianna Pellegrini, Marco Spada, Gabriella Canavese
Teduglutide is a glucagon-like peptide-2 (GLP-2) analog employed in patients with short bowel syndrome (SBS) to reduce the need of parenteral nutrition in these patients, by virtue of its effects on enteric function. The experimental studies reported that the stimulating action of GLP-2 on epithelial turnover implies the potential development of dysplastic and neoplastic lesion. However, the clinical trials could not detect preneoplastic lesions on histologic material, and in a recent pilot study the occurrence of polyps was similar before and after treatment and included only low-grade dysplastic lesions...
2022: Frontiers in Nutrition
https://read.qxmd.com/read/35801030/bedside-ultrasonic-localization-of-the-nasogastric-tube-in-a-patient-with-severe-covid-19-a-case-report
#11
Xiao-Ju Zhu, Shui-Xia Liu, Qiu-Tang Li, Yuan-Jing Jiang
BACKGROUND: The indwelling nasogastric tube is commonly used for supplying enteral nutrition to patients who are unable to feed themselves, and accurate positioning is essential in the indwelling nasogastric tube in the body of the aforementioned patients. In clinical practice, abdominal radiography, auscultation, and clinical determination of the pH of the gastric juice are routinely used by medical personnel to determine the position of the tube; however, those treatments have proved limitations in specific cases...
May 26, 2022: World Journal of Clinical Cases
https://read.qxmd.com/read/34829056/a-highly-sensitive-and-selective-fluorescent-probe-using-mpa-inp-zns-qds-for-detection-of-trace-amounts-of-cu-2-in-water
#12
JOURNAL ARTICLE
Zeyu Xu, Yizhong Wang, Jiaran Zhang, Ce Shi, Xinting Yang
Detection of copper (II) ions (Cu2+ ) in water is important for preventing them from entering the human body to preserve human health. Here, a highly sensitive and selective fluorescence probe that uses mercaptopropionic acid (MPA)-capped InP/ZnS quantum dots (MPA-InP/ZnS QDs) was proposed for the detection of trace amounts of Cu2+ in water. The fluorescence of MPA-InP/ZnS QDs can be quenched significantly in the presence of Cu2+ , and the fluorescence intensity shows excellent linearity when the concentration of Cu2+ varies from 0-1000 nM; this probe also exhibits an extremely low limit of detection of 0...
November 11, 2021: Foods (Basel, Switzerland)
https://read.qxmd.com/read/34646537/effect-of-pinolenic-acid-on-oxidative-stress-injury-in-hepg2-cells-induced-by-h-2-o-2
#13
JOURNAL ARTICLE
Yang Zhao, Sainan Liu, Zhili Sheng, Xue Li, Yanan Chang, Weichang Dai, Sui Kiat Chang, Junmei Liu, Yuchun Yang
To investigate the effect and mechanism of pinolenic acid (PNA) on H2 O2 -induced oxidative stress injury in HepG2 cells. Methods: PNA was used to regulate oxidative stress injury of HepG2 cells induced by H2 O2 . Quantification of cell survival rate, accumulation of intracellular reactive oxygen species (ROS), and expression levels of anti-oxidation-related genes were determined using MTT, fluorescent probe technology (DCFH-DA), and real-time quantitative reverse transcription polymerase chain technology (qRT-PCR) method, respectively...
October 2021: Food Science & Nutrition
https://read.qxmd.com/read/34308701/influence-of-homogenization-in-the-physicochemical-quality-of-human-milk-and-fat-retention-in-gastric-tubes
#14
JOURNAL ARTICLE
Kely de Paula Correa, Monique Ellen Torres da Silva, Davi Rocha Bernardes de Oliveira, André Fernando de Oliveira, Igor Jose Boggione Santos, Eduardo Basílio de Oliveira, Jane Sélia Dos Reis Coimbra
BACKGROUND: The retention of human milk nutrients in gastric tubes used to feed premature infants is a challenge to be overcome. RESEARCH AIMS: To evaluate (1) the performance of six homogenizers (mixing processor, piston valve, ultrasonic bath, ultraturrax, stirring mixer, and ultrasound probe) for the fat retention reduction in gastric tubes; (2) the influence of the best homogenization conditions on the fatty acid and protein profiles of human milk; and (3) the cost/benefit ratio for the inclusion of homogenization as a new step in human milk processing...
July 26, 2021: Journal of Human Lactation
https://read.qxmd.com/read/34264559/-assessment-of-nutritive-status-and-its-correction-in-oncological-patients-after-operations-in-the-hepatopancreatoduodenal-zone
#15
JOURNAL ARTICLE
Sh K Davanov, D V Vasilev, N A Kabildina, S V Plyаssovskayа
Surgical interventions in the hepatopancreatoduodenal zone in cancer patients are associated with high risk of nutritional deficiency in the postoperative period. This feature is due to both the volume of the operation itself (pancreatoduodenectomy), and the predominance of catabolic processes in the early postoperative period. In this regard, the monitoring of the main indicators of carbohydrate, protein and fat metabolism in the early postoperative period becomes fundamental for choosing the correct tactics of nutritional support for this patients...
2021: Voprosy Pitaniia
https://read.qxmd.com/read/34138767/what-is-the-leaky-gut-clinical-considerations-in-humans
#16
REVIEW
Michael Camilleri
PURPOSE OF REVIEW: To review the components of the intestinal barrier, the practical measurements of intestinal permeability, and the clinical conditions associated with altered intestinal barrier function, and to summarize the effects of dietary substances that fortify or weaken the intestinal barrier. RECENT FINDINGS: The intestinal barrier includes surface mucus, epithelial layer, and immune defense mechanisms. Transport across the epithelium may result from increased paracellular transport, apoptosis, or transcellular permeability...
September 1, 2021: Current Opinion in Clinical Nutrition and Metabolic Care
https://read.qxmd.com/read/34066386/enteral-nutrition-by-nasogastric-tube-in-adult-patients-under-palliative-care-a-systematic-review
#17
JOURNAL ARTICLE
Eduardo Sánchez-Sánchez, María Araceli Ruano-Álvarez, Jara Díaz-Jiménez, Antonio Jesús Díaz, Francisco Javier Ordonez
Nutritional management of patients under palliative care can lead to ethical issues, especially when Enteral Nutrition (EN) is prescribed by nasogastric tube (NGT). The aim of this review is to know the current status in the management of EN by NG tube in patients under palliative care, and its effect in their wellbeing and quality of life. The following databases were used: PubMed, Web of Science (WOS), Scopus, Scielo, Embase and Medline. After inclusion and exclusion criteria were applied, as well as different qualities screening, a total of three entries were used, published between 2015 and 2020...
May 6, 2021: Nutrients
https://read.qxmd.com/read/33902762/homogenised-and-pasteurised-human-milk-lipid-profile-and-effect-as-a-supplement-in-the-enteral-diet-of-wistar-rats
#18
JOURNAL ARTICLE
Kely de Paula Correa, Monique E T Silva, Otávio S Ribeiro, Sérgio L P Matta, Maria do Carmo G Peluzio, Eduardo B Oliveira, Jane S Dos R Coimbra
The retention of human milk (HM) fat in nasogastric probes of infusion pumps can be observed during the feed of infants unable to suck at the mother's breast. The lack of homogenisation of HM could contribute to the fat holding. Therefore, the present study evaluated (i) the influence of homogenisation on milk fat retaining in infant feeding probes and (ii) the in vivo effect of the homogenisation on lipid absorption by Wistar rats. The animals were fed with HM treated following two processing conditions, that is, pasteurised and homogenised-pasteurised...
March 14, 2022: British Journal of Nutrition
https://read.qxmd.com/read/33876338/does-ultrasonographic-assessment-of-gastric-antrum-correlate-with-gastric-residual-volume-in-critically-ill-patients-a-prospective-observational-study
#19
JOURNAL ARTICLE
Gurhan Taskin, Volkan Inal, Levent Yamanel
This study aimed to evaluate the relationship between ultrasonographic gastric antral measurements and aspirated gastric residual volume (GRV) in mechanically ventilated critically ill patients receiving enteral nutrition (EN). This prospective observational study included 56 enterally-fed critically ill patients in one-year period. All imaging procedures were done at 30-degree head-of-bed elevation and supine position on epigastric region of abdomen with 2.5-6 MHz convex-array probe just before routine GRV aspiration...
August 2021: Journal of Clinical Monitoring and Computing
https://read.qxmd.com/read/33599881/ultrasonography-guided-post-pyloric-feeding-tube-insertion-in-medical-intensive-care-unit-patients
#20
JOURNAL ARTICLE
Uğur Özdemir, Şeyma Yıldız, Gulbin Aygencel, Melda Türkoğlu
In this study, we investigated placement rate, complication rate and time spent of successful post-pyloric enteral feeding (PPEF) tube insertion procedure guided by ultrasonography (USG). The patients who required enteral nutrition and who admitted to medical intensive care unit (MICU) of Gazi University Hospital were included to this single-center, prospective, cohort study. It was aimed to insert the enteral feeding tube into the proximal duodenum as the post-pyloric area by ultrasonography guidance. During the PPEF tube insertion procedure, the linear probe was used to display the proximal esophagus and the convex probe was used to display the post-pyloric area, antrum and pyloric channel...
February 18, 2021: Journal of Clinical Monitoring and Computing
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