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Aortic estenosis

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https://www.readbyqxmd.com/read/27644859/conservative-management-in-very-elderly-patients-with-severe-aortic-stenosis-time-to-change
#1
Eva Bernal, Albert Ariza-Solé, Francesc Formiga, Emad Abu-Assi, Antoni Carol, Laura Galián, Antoni Bayés-Genís, Hugo González Saldivar, Pablo Díez-Villanueva, Manuel Martínez Sellés
BACKGROUND: Despite current recommendations, a high percentage of patients with severe symptomatic aortic stenosis are managed conservatively. The aim of this study was to study symptomatic patients undergoing conservative management from the IDEAS registry, describing their baseline clinical characteristics, mortality, and the causes according to the reason for conservative management. METHODS: Consecutive patients with severe aortic stenosis diagnosed at 48 centers during January 2014 were included...
September 16, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/27239021/comparison-of-1-year-outcome-in-patients-with-severe-aorta-stenosis-treated-conservatively-or-by-aortic-valve-replacement-or-by-percutaneous-transcatheter-aortic-valve-implantation-data-from-a-multicenter-spanish-registry
#2
Hugo González-Saldivar, Carlos Rodriguez-Pascual, Gonzalo de la Morena, Covadonga Fernández-Golfín, Carmen Amorós, Mario Baquero Alonso, Luis Martínez Dolz, Albert Ariza Solé, Gabriela Guzmán-Martínez, Juan José Gómez-Doblas, Antonio Arribas Jiménez, María Eugenia Fuentes, Laura Galian Gay, Martin Ruiz Ortiz, Pablo Avanzas, Emad Abu-Assi, Tomás Ripoll-Vera, Oscar Díaz-Castro, Eduardo P Osinalde, Manuel Martínez-Sellés
The factors that influence decision making in severe aortic stenosis (AS) are unknown. Our aim was to assess, in patients with severe AS, the determinants of management and prognosis in a multicenter registry that enrolled all consecutive adults with severe AS during a 1-month period. One-year follow-up was obtained in all patients and included vital status and aortic valve intervention (aortic valve replacement [AVR] and transcatheter aortic valve implantation [TAVI]). A total of 726 patients were included, mean age was 77...
July 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/25885873/comorbidity-and-intervention-in-octogenarians-with-severe-symptomatic-aortic-stenosis
#3
Manuel Martínez-Sellés, Pablo Díez-Villanueva, Domingo Sánchez-Sendin, Amelia Carro Hevia, Juan José Gómez Doblas, Bernardo García de la Villa, Luis Cornide, Albert Alonso Tello, Ramón Andión Ogando, Tomás Ripoll Vera, Antonio Arribas Jiménez, Pilar Carrillo, Carlos Rodríguez Pascual, Maria Casares I Romeva, Xavier Borras, Sandra Vázquez, Ramón López-Palop
BACKGROUND: The benefit from intervention in elderly patients with symptomatic severe aortic stenosis (AS) and high comorbidity is unknown. Our aims were to establish the correlation between the Charlson comorbidity index and the prognosis of octogenarians with symptomatic sever AS and to identify patients who might not benefit from intervention. METHODS: We used the data from PEGASO (Pronóstico de la Estenosis Grave Aórtica Sintomática del Octogenario--Prognosis of symptomatic severe aortic stenosis in octogenarians), a prospective registry that included consecutively 928 patients aged ≥ 80 years with severe symptomatic AS...
2015: International Journal of Cardiology
https://www.readbyqxmd.com/read/18192703/association-between-self-replicating-calcifying-nanoparticles-and-aortic-stenosis-a-possible-link-to-valve-calcification
#4
Miguel A Bratos-Pérez, Pedro L Sánchez, Susana García de Cruz, Eduardo Villacorta, Igor F Palacios, José M Fernández-Fernández, Salvatore Di Stefano, Antonio Orduña-Domingo, Yolanda Carrascal, Pedro Mota, Cándido Martín-Luengo, Javier Bermejo, José A San Roman, Antonio Rodríguez-Torres, Francisco Fernández-Avilés et al.
AIMS: Among various hypotheses proposed for pathological tissue calcification, recent evidence supports the possibility that self-replicating calcifying nanoparticles (CNPs) can contribute to such calcification. These CNPs have been detected and isolated from calcified human tissues, including blood vessels and kidney stones, and are referred to as nanobacteria. We evaluated calcific aortic valves for the presence of CNP. METHODS AND RESULTS: Calcific aortic valves were obtained from 75 patients undergoing surgical valve replacement...
February 2008: European Heart Journal
https://www.readbyqxmd.com/read/16377290/relation-of-circulating-c-reactive-protein-to-progression-of-aortic-valve-stenosis
#5
Pedro L Sánchez, Jose L Santos, Juan Carlos Kaski, Ignacio Cruz, Antonio Arribas, Eduardo Villacorta, Manuel Cascon, Igor F Palacios, Candido Martin-Luengo et al.
C-reactive protein (CRP) is a marker of inflammation and predicts outcome in apparently healthy subjects and patients with coronary artery disease. Systemic inflammation is present in patients with aortic valve stenosis (AS). The aim of this prospective study was to assess whether CRP levels predict the progression of AS severity. Blood samples for high-sensitivity CRP measurements and echocardiographic data were obtained in 43 patients (70% men; mean age 73 +/- 8 years) with asymptomatic degenerative AS at study entry...
January 1, 2006: American Journal of Cardiology
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