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https://www.readbyqxmd.com/read/28813851/lokomat-therapy-in-colombia-current-state-and-cognitive-aspects
#1
Marcela Munera, Alexandra Marroquin, Laura Jimenez, Juan S Lara, Catalina Gomez, Sandra Rodriguez, Luis E Rodriguez, Carlos A Cifuentes
Neurological disorders frequently affect walking function which is one of the most fundamental skills to improve quality of life and autonomy, and Lokomat has been a key piece for gait's rehabilitation. In this study, a diagnosis about the development of the Robot-assisted therapy rehabilitation with Lokomat in Colombia is made. The study was performed by collecting some anthropometric and demographic data of the patients that use Lokomat, followed by a survey of cognitive aspects. With the purpose to compare the current state of the robotic therapies it was found that in Colombia the benefits of this treatment have not being fully exploited...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28806970/transcriptomic-analysis-of-the-response-of-acropora-millepora-to-hypo-osmotic-stress-provides-insights-into-dmsp-biosynthesis-by-corals
#2
Catalina Aguilar, Jean-Baptiste Raina, Cherie A Motti, Sylvain Fôret, David C Hayward, Bruno Lapeyre, David G Bourne, David J Miller
BACKGROUND: Dimethylsulfoniopropionate (DMSP) is a small sulphur compound which is produced in prodigious amounts in the oceans and plays a pivotal role in the marine sulfur cycle. Until recently, DMSP was believed to be synthesized exclusively by photosynthetic organisms; however we now know that corals and specific bacteria can also produce this compound. Corals are major sources of DMSP, but the molecular basis for its biosynthesis is unknown in these organisms. RESULTS: Here we used salinity stress, which is known to trigger DMSP production in other organisms, in conjunction with transcriptomics to identify coral genes likely to be involved in DMSP biosynthesis...
August 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28803432/quality-of-life-in-home-ventilated-children-and-their-families
#3
Rafael González, Amaya Bustinza, Sarah N Fernandez, Miriam García, Silvia Rodriguez, Ma Ángeles García-Teresa, Mirella Gaboli, Silvia García, Olaia Sardón, Diego García, Antonio Salcedo, Antonio Rodríguez, Ma Carmen Luna, Arturo Hernández, Catalina González, Alberto Medina, Estela Pérez, Alicia Callejón, Juan D Toledo, Mercedes Herranz, Jesús López-Herce
HMV (home mechanical ventilation) in children has increased over the last years. The aim of the study was to assess perceived quality of life (QOL) of these children and their families as well as the problems they face in their daily life.We performed a multicentric cross-sectional study using a semi-structured interview about the impact of HMV on families and an evaluation questionnaire about perceived QOL by the patient and their families (pediatric quality of life questionnaire (PedsQL4.0)). We studied 41 subjects (mean age 8...
August 12, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28797068/virulence-profiles-and-innate-immune-responses-against-highly-lethal-multidrug-resistant-nosocomial-isolates-of-acinetobacter-baumannii-from-a-tertiary-care-hospital-in-mexico
#4
Roberto Rosales-Reyes, Catalina Gayosso-Vázquez, José Luis Fernández-Vázquez, Ma Dolores Jarillo-Quijada, César Rivera-Benítez, José Ignacio Santos-Preciado, María Dolores Alcántar-Curiel
Virulence profiles and innate immune responses were studied in Acinetobacter baumannii from nosocomial infections collected over one year in a tertiary care hospital in Mexico. A. baumannii were identified by VITEK 2 System followed by susceptibility tests. Carbapenemase genes, active efflux mechanism to imipenem and meropenem and outer membrane proteins profile were analyzed to evaluate their role on the activity of carbapenem resistance. All isolates were genotyped by pulsed field gel electrophoresis. The ability to form biofilm was determined on a polystyrene surface...
2017: PloS One
https://www.readbyqxmd.com/read/28795338/evaluation-of-patient-and-family-engagement-strategies-to-improve-medication-safety
#5
REVIEW
Julia M Kim, Catalina Suarez-Cuervo, Zackary Berger, Joy Lee, Jessica Gayleard, Carol Rosenberg, Natalia Nagy, Kristina Weeks, Sydney Dy
BACKGROUND: Patient and family engagement (PFE) is critical for patient safety. We systematically reviewed types of PFE strategies implemented and their impact on medication safety. METHODS: We searched MEDLINE, EMBASE, reference lists and websites to August 2016. Two investigators independently reviewed all abstracts and articles, and articles were additionally reviewed by two senior investigators for selection. One investigator abstracted data and two investigators reviewed the data for accuracy...
August 9, 2017: Patient
https://www.readbyqxmd.com/read/28795332/the-patterns-of-non-vitamin-k-antagonist-oral-anticoagulants-noacs-use-in-patients-with-atrial-fibrillation-in-seven-balkan-countries-a-report-from-the-balkan-af-survey
#6
Tatjana S Potpara, Elina Trendafilova, Gheorghe-Andrei Dan, Artan Goda, Zumreta Kusljugic, Sime Manola, Ljilja Music, Viktor Gjini, Belma Pojskic, Mircea Ioakim Popescu, Catalina Arsenescu Georgescu, Elena S Dimitrova, Delyana Kamenova, Uliks Ekmeciu, Denis Mrsic, Ana Nenezic, Sandro Brusich, Srdjan Milanov, Ivan Zeljkovic, Gregory Y H Lip
INTRODUCTION: Data on management of atrial fibrillation (AF) in the Balkan Region are scarce. To capture the patterns in AF management in contemporary clinical practice in the Balkan countries a prospective survey was conducted between December 2014 and February 2015, and we report results pertinent to the use of non-vitamin K antagonist oral anticoagulants (NOACs). METHODS: A 14-week prospective, multicenter survey of consecutive AF patients seen by cardiologists or internal medicine specialists was conducted in Albania, Bosnia and Herzegovina, Bulgaria, Croatia, Montenegro, Romania, and Serbia (a total of about 50 million inhabitants)...
August 9, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28795284/dermatofibrosarcoma-protuberans
#7
REVIEW
Alvaro E Acosta, Catalina Santa Vélez
Dermatofibrosarcoma protuberans (DFSP) is a slow growing tumor with a very low metastatic potential but with significant subclinical extension and great capacity for local destruction. Thus, the first surgeon approached with such challenging tumor must attempt to cure the patient with a method that spares healthy tissue and ensures an optimal oncological, functional, and esthetic result. The treatment of DFSP often requires a multidisciplinary approach. Depending on location, dermatologic surgeons, surgical oncologists, head and neck surgeons, neurosurgeons, plastic surgeons, and occasionally medical oncologists may be involved with the management...
August 10, 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/28793302/safety-of-adrenaline-use-in-anaphylaxis-a-multicentre-register
#8
Victòria Cardona, Laia Ferré-Ybarz, Mar Guilarte, Nuria Moreno-Pérez, Catalina Gómez-Galán, Eva Alcoceba-Borràs, Maria Belén Delavalle, Teresa Garriga-Baraut
BACKGROUND: The use of intramuscular adrenaline to treat anaphylaxis is suboptimal, despite being the first-line treatment recommended by national and international anaphylaxis guidelines. Fear of potentially severe side effects may be one of the underlying factors. The aim of this study was to assess the incidence and severity of adverse side effects after the use of adrenaline in anaphylaxis, as well as potential risk factors. METHODS: Observational study based on a multicenter online registry of cases of adrenaline administration for suspected anaphylaxis...
August 9, 2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/28792719/evaluation-of-3-hemoglobin-a1c-point-of-care-instruments-point-of-care-testing-for-hba1c-evaluation-of-cobas-b101-b-analyst-and-afinion%C3%A2
#9
María De Toro-Crespo, Catalina Sánchez-Mora, Patricia Fernández-Riejos, José M Maesa-Márquez, Concepción González-Rodríguez
No abstract text is available yet for this article.
July 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28792228/what-do-you-say-before-you-relapse-how-language-use-in-a-peer-to-peer-online-discussion-forum-predicts-risky-drinking-among-those-in-recovery
#10
Rachel Kornfield, Catalina L Toma, Dhavan V Shah, Tae Joon Moon, David H Gustafson
Increasingly, individuals with alcohol use disorder (AUD) seek and provide support for relapse prevention in text-based online environments such as discussion forums. This paper investigates whether language use within a peer-to-peer discussion forum can predict future relapse among individuals treated for AUD. A total of 104 AUD sufferers who had completed residential treatment participated in a mobile phone-based relapse-prevention program, where they communicated via an online forum over the course of a year...
August 9, 2017: Health Communication
https://www.readbyqxmd.com/read/28790909/estimation-of-synaptic-conductances-in-presence-of-nonlinear-effects-caused-by-subthreshold-ionic-currents
#11
Catalina Vich, Rune W Berg, Antoni Guillamon, Susanne Ditlevsen
Subthreshold fluctuations in neuronal membrane potential traces contain nonlinear components, and employing nonlinear models might improve the statistical inference. We propose a new strategy to estimate synaptic conductances, which has been tested using in silico data and applied to in vivo recordings. The model is constructed to capture the nonlinearities caused by subthreshold activated currents, and the estimation procedure can discern between excitatory and inhibitory conductances using only one membrane potential trace...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28790210/membrane-distribution-of-the-pseudomonas-quinolone-signal-modulates-outer-membrane-vesicle-production-in-pseudomonas%C3%A2-aeruginosa
#12
Catalina Florez, Julie E Raab, Adam C Cooke, Jeffrey W Schertzer
The Pseudomonas quinolone signal (PQS) is an important quorum-sensing molecule in Pseudomonas aeruginosa that also mediates its own packaging and transport by stimulating outer membrane vesicle (OMV) formation. Because OMVs have been implicated in many virulence-associated behaviors, it is critical that we understand how they are formed. Our group proposed the bilayer-couple model for OMV biogenesis, where PQS intercalates into the outer membrane, causing expansion of the outer leaflet and consequently inducing curvature...
August 8, 2017: MBio
https://www.readbyqxmd.com/read/28789991/potential-impact-of-a-prehospital-redirection-system-for-refractory-cardiac-arrest
#13
Alexis Cournoyer, Éric Notebaert, Luc de Montigny, Sylvie Cossette, Luc Londei-Leduc, Massimiliano Iseppon, Yoan Lamarche, Catalina Sokoloff, Judy Morris, Éric Piette, Raoul Daoust, Jean-Marc Chauny, Dave Ross, Dominique Lafrance, Eli Segal, Yiorgos Alexandros Cavayas, Jean Paquet, André Denault
AIM: A change in prehospital redirection practice could potentially increase the proportion of E-CPR eligible patients with out-of-hospital cardiac arrest (OHCA) transported to extracorporeal cardiopulmonary resuscitation (E-CPR) capable centers. The objective of this study was to quantify this potential increase of E-CPR candidates transported to E-CPR capable centers. METHODS: Adults with non-traumatic OHCA refractory to 15min of resuscitation were selected from a registry of adult OHCA collected between 2010 and 2015 in Montreal, Canada...
August 5, 2017: Resuscitation
https://www.readbyqxmd.com/read/28789716/in-vitro-antileishmanial-activity-and-iron-superoxide-dismutase-inhibition-of-arylamine-mannich-base-derivatives
#14
Alvaro Martin-Montes, Mery Santivañez-Veliz, Elsa Moreno-Viguri, Rubén Martín-Escolano, Carmen Jiménez-Montes, Catalina Lopez-Gonzalez, Clotilde Marín, Carmen Sanmartín, Ramón Gutiérrez Sánchez, Manuel Sánchez-Moreno, Silvia Pérez-Silanes
Leishmaniasis is one of the world's most neglected diseases, and it has a worldwide prevalence of 12 million. There are no effective human vaccines for its prevention, and treatment is hampered by outdated drugs. Therefore, research aiming at the development of new therapeutic tools to fight leishmaniasis remains a crucial goal today. With this purpose in mind, we present 20 arylaminoketone derivatives with a very interesting in vitro and in vivo efficacy against Trypanosoma cruzi that have now been studied against promastigote and amastigote forms of Leishmania infantum, Leishmania donovani and Leishmania braziliensis strains...
August 9, 2017: Parasitology
https://www.readbyqxmd.com/read/28781825/hepatotoxicity-after-high-dose-intravenous-methylprednisolone-in-multiple-sclerosis-patients
#15
Milagros Hidalgo de la Cruz, Jahir Andrés Miranda Acuña, Alberto Lozano Ros, María Vega Catalina, Emilio Salinero Paniagua, Gerardo Clemente Ricote, Clara Dionisia De Andrés Frutos, María Luisa Martínez Ginés
Hepatotoxicity is a rare adverse event of methylprednisolone that should be considered in clinical practice. In patients at risk, we propose liver function surveillance, by measuring hepatic enzymes concentration 15-30 days after methylprednisolone administration. Additionally, we propose ACTH, dexamethasone, or plasma exchange as alternate treatment options for these patients.
August 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28776467/pharmacogenetics-and-the-treatment-of-asthma
#16
María Isidoro-García, Almudena Sánchez-Martín, Asunción García-Sánchez, Catalina Sanz, Belén García-Berrocal, Ignacio Dávila
Heterogeneity defines both the natural history of asthma as well as patient's response to treatment. Pharmacogenomics contribute to understand the genetic basis of drug response and thus to define new therapeutic targets or molecular biomarkers to evaluate treatment effectiveness. This review is initially focused on different genes so far involved in the pharmacological response to asthma treatment. Specific considerations regarding allergic asthma, the pharmacogenetics aspects of polypharmacy and the application of pharmacogenomics in new drugs in asthma will also be addressed...
August 4, 2017: Pharmacogenomics
https://www.readbyqxmd.com/read/28773001/effect-of-different-carbon-sources-on-bacterial-nanocellulose-production-and-structure-using-the-low-ph-resistant-strain-komagataeibacter-medellinensis
#17
Carlos Molina-Ramírez, Margarita Castro, Marlon Osorio, Mabel Torres-Taborda, Beatriz Gómez, Robin Zuluaga, Catalina Gómez, Piedad Gañán, Orlando J Rojas, Cristina Castro
Bacterial cellulose (BC) is a polymer obtained by fermentation with microorganism of different genera. Recently, new producer species have been discovered, which require identification of the most important variables affecting cellulose production. In this work, the influence of different carbon sources in BC production by a novel low pH-resistant strain Komagataeibacter medellinensis was established. The Hestrin-Schramm culture medium was used as a reference and was compared to other media comprising glucose, fructose, and sucrose, used as carbon sources at three concentrations (1, 2, and 3% w/v)...
June 11, 2017: Materials
https://www.readbyqxmd.com/read/28772904/hydrogels-synthesized-by-electron-beam-irradiation-for-heavy-metal-adsorption
#18
Elena Manaila, Gabriela Craciun, Daniel Ighigeanu, Catalina Cimpeanu, Catalina Barna, Viorel Fugaru
Poly(acrylamide co-acrylic acid) hydrogels were prepared by free-radical copolymerization of acrylamide and acrylic acid in aqueous solutions using electron beam irradiation in the dose range of 2.5 kGy to 6 kGy in atmospheric conditions and at room temperature. The influence of the absorbed dose, the amount of cross-linker (trimethylolpropane trimethacrylate) and initiator (potassium persulfate) on the swelling properties and the diffusion coefficient and network parameters of hydrogels were investigated. The structure and morphology of hydrogels were characterized by Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM)...
May 18, 2017: Materials
https://www.readbyqxmd.com/read/28769774/fenofibrate-administration-reduces-alcohol-and-saccharin-intake-in-rats-possible-effects-at-peripheral-and-central-levels
#19
Mario Rivera-Meza, Daniel Muñoz, Erik Jerez, María E Quintanilla, Catalina Salinas-Luypaert, Katia Fernandez, Eduardo Karahanian
We have previously shown that the administration of fenofibrate to high-drinker UChB rats markedly reduces voluntary ethanol intake. Fenofibrate is a peroxisome proliferator-activated receptor alpha (PPARα) agonist, which induces the proliferation of peroxisomes in the liver, leading to increases in catalase levels that result in acetaldehyde accumulation at aversive levels in the blood when animals consume ethanol. In these new studies, we aimed to investigate if the effect of fenofibrate on ethanol intake is produced exclusively in the liver (increasing catalase and systemic levels of acetaldehyde) or there might be additional effects at central level...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28767679/compartmentalized-metabolic-network-reconstruction-of-microbial-communities-to-determine-the-effect-of-agricultural-intervention-on-soils
#20
María Camila Alvarez-Silva, Astrid Catalina Álvarez-Yela, Fabio Gómez-Cano, María Mercedes Zambrano, Johana Husserl, Giovanna Danies, Silvia Restrepo, Andrés Fernando González-Barrios
Soil microbial communities are responsible for a wide range of ecological processes and have an important economic impact in agriculture. Determining the metabolic processes performed by microbial communities is crucial for understanding and managing ecosystem properties. Metagenomic approaches allow the elucidation of the main metabolic processes that determine the performance of microbial communities under different environmental conditions and perturbations. Here we present the first compartmentalized metabolic reconstruction at a metagenomics scale of a microbial ecosystem...
2017: PloS One
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