keyword
MENU ▼
Read by QxMD icon Read
search

catalina

keyword
https://www.readbyqxmd.com/read/29140767/genomic-medicine-without-borders-which-strategies-should-developing-countries-employ-to-invest-in-precision-medicine-a-new-fast-second-winner-strategy
#1
Konstantinos Mitropoulos, David N Cooper, Christina Mitropoulou, Spiros Agathos, Jürgen K V Reichardt, Fatima Al-Maskari, Wasun Chantratita, Ambroise Wonkam, Collet Dandara, Theodora Katsila, Catalina Lopez-Correa, Bassam R Ali, George P Patrinos
Genomic medicine has greatly matured in terms of its technical capabilities, but the diffusion of genomic innovations worldwide faces significant barriers beyond mere access to technology. New global development strategies are sorely needed for biotechnologies such as genomics and their applications toward precision medicine without borders. Moreover, diffusion of genomic medicine globally cannot adhere to a "one-size-fits-all-countries" development strategy, in the same way that drug treatments should be customized...
November 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/29133218/cluster-analysis-identifies-3-phenotypes-within-allergic-asthma
#2
María Paz Sendín-Hernández, Carmelo Ávila-Zarza, Catalina Sanz, Asunción García-Sánchez, Elena Marcos-Vadillo, Francisco J Muñoz-Bellido, Elena Laffond, Christian Domingo, María Isidoro-García, Ignacio Dávila
BACKGROUND: Asthma is a heterogeneous chronic disease with different clinical expressions and responses to treatment. In recent years, several unbiased approaches based on clinical, physiological, and molecular features have described several phenotypes of asthma. Some phenotypes are allergic, but little is known about whether these phenotypes can be further subdivided. OBJECTIVE: We aimed to phenotype patients with allergic asthma using an unbiased approach based on multivariate classification techniques (unsupervised hierarchical cluster analysis)...
November 10, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29132545/nanoformulation-a-useful-therapeutic-strategy-for-improving-neuroprotection-and-the-neurorestorative-potential-in-experimental-models-of-parkinson-s-disease
#3
Jose V Lafuente, Catalina Requejo, Alejandro Carrasco, Harkaitz Bengoetxea
Parkinson's disease (PD) is the second most frequent neurodegenerative disorder, but current therapies are only symptomatic. Experimental models are necessary to go deeper in the comprehension of pathophysiological mechanism and to assess new therapeutic strategies. The unilateral 6-hydroxydopamine (6-OHDA) lesion either in medial forebrain bundle (MFB) or into the striatum in rats affords to study various stages of PD depending on the evolution time lapsed. A promising alternative to address the neurodegenerative process is the use of neurotrophic factors; but its clinical use has been limited due to its short half-life and rapid degradation after in vivo administration, along with difficulties for crossing the blood-brain barrier (BBB)...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/29129237/iron-induced-pro-oxidant-and-pro-lipogenic-responses-in-relation-to-impaired-synthesis-and-accretion-of-long-chain-polyunsaturated-fatty-acids-in-rat-hepatic-and-extrahepatic-tissues
#4
Rodrigo Valenzuela, Miguel Ángel Rincón-Cervera, Francisca Echeverría, Cynthia Barrera, Alejandra Espinosa, María Catalina Hernández-Rodas, Macarena Ortiz, Alfonso Valenzuela, Luis A Videla
OBJECTIVES: Iron is involved in processes involving oxygen transfer and utilization. Excess iron is linked to cardiovascular diseases and some types of cancer. Iron overload is associated with oxidative stress development, and may have important interactions with lipid metabolism in the liver favoring the development and progression of non-alcoholic fatty liver disease. The aim of the study described here was to assess the effect of high intake of iron on oxidative stress-related parameters, lipid metabolism, and levels of long-chain polyunsaturated fatty acids (LCPUFAs) in liver and other tissues of the rat...
January 2018: Nutrition
https://www.readbyqxmd.com/read/29126968/jnk-signaling-pathway-regulates-sorbitol-induced-tau-proteolysis-and-apoptosis-in-sh-sy5y-cells-by-targeting-caspase-3
#5
Marta Olivera Santa-Catalina, Montaña Caballero Bermejo, Ricardo Argent, Juan C Alonso, Francisco Centeno, María J Lorenzo
Growing evidence suggests that Diabetes Mellitus increases the risk of developing Alzheimer's disease. It is well known that hyperglycemia, a key feature of Diabetes Mellitus, may induce plasma osmolarity disturbances. Both hyperglycemia and hyperosmolarity promote the altered post-translational regulation of microtubule-associated protein Tau. Interestingly, abnormal hyperphosphorylation and cleavage of Tau have been proven to lead to the genesis of filamentous structures referred to as neurofibrillary tangles, the main pathological hallmark of Alzheimer's disease...
November 7, 2017: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29126428/validity-and-reliability-of-the-spanish-version-of-the-organizational-readiness-for-knowledge-translation-or4kt-questionnaire
#6
Gonzalo Grandes, Paola Bully, Catalina Martinez, Marie-Pierre Gagnon
BACKGROUND: Organizational readiness to change healthcare practice is a major determinant of successful implementation of evidence-based interventions. However, we lack of comprehensive, valid, and reliable instruments to measure it. We assessed the validity and reliability of the Spanish version of the Organizational Readiness for Knowledge Translation (OR4KT) questionnaire in the context of the implementation of the Prescribe Vida Saludable III project, which seeks to strengthen health promotion and chronic disease prevention in primary healthcare organizations of the Osakidetza (Basque Health Service, Spain)...
November 10, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29113934/validating-ehr-clinical-models-using-ontology-patterns
#7
Catalina Martínez-Costa, Stefan Schulz
Clinical models are artefacts that specify how information is structured in electronic health records (EHRs). However, the makeup of clinical models is not guided by any formal constraint beyond a semantically vague information model. We address this gap by advocating ontology design patterns as a mechanism that makes the semantics of clinical models explicit. This paper demonstrates how ontology design patterns can validate existing clinical models using SHACL. Based on the Clinical Information Modelling Initiative (CIMI), we show how ontology patterns detect both modeling and terminology binding errors in CIMI models...
November 4, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29107893/lung-regeneration-after-toxic-injury-is-improved-in-absence-of-dioxin-receptor
#8
Antonio Morales-Hernández, Ana Nacarino-Palma, Nuria Moreno-Marín, Eva Barrasa, Beroé Paniagua-Quiñones, Inmaculada Catalina-Fernández, Alberto Alvarez-Barrientos, Xosé R Bustelo, Jaime M Merino, Pedro M Fernández-Salguero
Recent experimental evidences from cellular systems and from mammalian and non-mammalian animal models highlight novel functions for the aryl hydrocarbon/dioxin receptor (AhR) in maintaining cell differentiation and tissue homeostasis. Notably, AhR depletion stimulates an undifferentiated and pluripotent phenotype likely associated to a mesenchymal transition in epithelial cells and to increased primary tumorigenesis and metastasis in melanoma. In this work, we have used a lung model of epithelial regeneration to investigate whether AhR regulates proper tissue repair by adjusting the expansion of undifferentiated stem-like cells...
October 12, 2017: Stem Cell Research
https://www.readbyqxmd.com/read/29102849/study-of-rabbit-erythrocytes-membrane-solubilization-by-sucrose-monomyristate-using-laurdan-and-phasor-analysis
#9
German Günther, Vanesa Herlax, M Pilar Lillo, Catalina Sandoval-Altamirano, Libnny N Belmar, Susana A Sánchez
The study of surfactant and bio membranes interaction is particularly complex due to the diversity in lipid composition and the presence of proteins in natural membranes. Even more difficult is the study of this interaction in vivo since cellular damage may complicate the interpretation of the results, therefore for most of the studies in this field either artificial or model systems are used. One of the model system most used to study biomembranes are erythrocytes due to their relatively simple structure (they lack nuclei and organelles having only the plasma membrane), their convenient experimental manipulation and availability...
November 1, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29102440/patient-satisfaction-with-radioguided-occult-lesion-localisation-using-iodine-125-seeds-rollis-versus-conventional-hookwire-localisation
#10
Jeremy S L Ong, Joelin Teh, Christobel Saunders, Anita G Bourke, Catalina Lizama, Jade Newton, Michael Phillips, Donna B Taylor
BACKGROUND: Women with impalpable or poorly palpable breast cancer require radiologically guided localisation prior to breast conserving surgery. Radioguided Occult Lesion Localisation using Iodine-125 Seed (ROLLIS) is an emerging alternative to conventional Hookwire Localisation (HWL). We compared ROLLIS with conventional HWL with respect to patient reported stress and discomfort related to the localisation procedure. PATIENTS AND METHODS: From September 2013 to January 2016, women who were eligible for breast conserving surgery with impalpable or poorly palpable histologically confirmed invasive or in-situ carcinoma were recruited to the multi-centre ROLLIS randomised controlled trial and underwent either ROLLIS or HWL...
October 16, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29102269/assessment-of-the-use-of-vitamin-c-and-e-supplements-concomitantly-to-antibiotic-treatment-against-helicobacter-pylori-a-systematic-review-and-meta-analysis
#11
Edgar Yaset Caicedo Ochoa, César Orlando Quintero Moreno, Yardany Rafael Méndez Fandiño, Sofía Catalina Sánchez Fonseca, Héctor Fabio Cortes Motta, Santiago Alejandro Guio Guerra
INTRODUCTION: Helicobacter pylori infections affect almost 50% of the world population, constituting a risk factor for benign and malignant gastrointestinal diseases. The increased resistance to antibiotic treatment against this infection represents a dilemma in the search of other therapeutic alternatives. OBJECTIVE: To determine the efficacy of the use of vitaminC and E supplements concomitantly to antibiotic treatment against H. pylori infections. METHODS: We performed a systematic review on the MedLine (PubMed), Embase and Cochrane Central Register of Clinical Trials (CENTRAL) databases, searching for studies evaluating the efficacy of vitaminC and/or E supplements in the antibiotic treatment of H...
November 1, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/29101682/interior-immigration-enforcement-and-political-participation-of-u-s-citizens-in-mixed-status-households
#12
Catalina Amuedo-Dorantes, Mary J Lopez
The 2000s have witnessed an expansion of interior immigration enforcement in the United States. At the same time, the country has experienced a major demographic transformation, with the number of U.S. citizens living in mixed-status households-that is, households where at least one family member is an unauthorized migrant-reaching 16 million. U.S. citizens living in mixed-status households are personally connected to the struggles experienced by their unauthorized family members. For them, immigration policy is likely to shape their current and future voting behavior...
November 3, 2017: Demography
https://www.readbyqxmd.com/read/29097064/acanthamoeba-t4-trophozoites-cross-the-mdck-epithelium-without-cell-damage-but-increase-paracellular-permeability-and-transepithelial-resistance-by-modifying-tight-junction-composition
#13
Catalina Flores-Maldonado, Arturo González-Robles, Lizbeth Salazar-Villatoro, Maritza Omaña-Molina, Juan Manuel Gallardo, Mónica González-Lázaro, Verónica Ivonne Hernández-Ramírez, Patricia Talamás-Rohana, Jacob Lorenzo-Morales, Adolfo Martínez-Palomo
Free-living amoebae of the genus Acanthamoeba are protozoa ubiquitously found in nature. Some species of the genus are potentially pathogenic for humans provoking keratitis in healthy individuals, often in contact lens wearers and opportunistic infections such as pneumonitis, fatal granulomatous encephalitis and skin infections, particularly in immunocompromised individuals. The pathogenic mechanisms of these amoebae are poorly understood, however it had been suggested that contact dependent mechanisms are important during invasion, regardless of the epithelia type, since amoebae penetrate epithelia separating tight junction (TJ)...
October 31, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/29089938/evidence-for-widespread-associations-between-neotropical-hymenopteran-insects-and-actinobacteria
#14
Bernal Matarrita-Carranza, Rolando D Moreira-Soto, Catalina Murillo-Cruz, Marielos Mora, Cameron R Currie, Adrián A Pinto-Tomas
The evolutionary success of hymenopteran insects has been associated with complex physiological and behavioral defense mechanisms against pathogens and parasites. Among these strategies are symbiotic associations between Hymenoptera and antibiotic-producing Actinobacteria, which provide protection to insect hosts. Herein, we examine associations between culturable Actinobacteria and 29 species of tropical hymenopteran insects that span five families, including Apidae (bees), Vespidae (wasps), and Formicidae (ants)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29082037/new-scenarios-of-chagas-disease-transmission-in-northern-colombia
#15
Catalina Tovar Acero, Jorge Negrete Peñata, Camila González, Cielo León, Mario Ortiz, Julio Chacón Pacheco, Elkin Monterrosa, Abraham Luna, Dina Ricardo Caldera, Lyda Espitia-Pérez
Chagas disease (CD) is a systemic parasitic infection caused by the flagellated form of Trypanosoma cruzi. Córdoba department, located in the Colombian Caribbean Coast, was not considered as a region at risk of T. cruzi transmission. In this article, we describe the first acute CD case in Salitral village in Sahagún, Córdoba, confirmed by microscopy and serological tests. Our results draw attention to a new scenario of transmission of acute CD in nonendemic areas of Colombia and highlight the need to include CD in the differential diagnosis of febrile syndromes in this region...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29078770/entomological-characterization-of-malaria-in-northern-colombia-through-vector-and-parasite-species-identification-and-analyses-of-spatial-distribution-and-infection-rates
#16
Camila González, Astrid Gisell Molina, Cielo León, Nicolás Salcedo, Silvia Rondón, Andrea Paz, Maria Claudia Atencia, Catalina Tovar, Mario Ortiz
BACKGROUND: Malaria remains a worldwide public health concern and, in Colombia, despite the efforts to stop malaria transmission, the incidence of cases has increased over the last few years. In this context, it is necessary to evaluate vector diversity, infection rates, and spatial distribution, to better understand disease transmission dynamics. This information may contribute to the planning and development of vector control strategies. RESULTS: A total of 778 Anopheles mosquitoes were collected in fifteen localities of Córdoba from August 2015 to October 2016...
October 27, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29071166/first-record-of-the-family-sphyrapodidae-gu%C3%A5-u-1980-crustacea-peracarida-apseudomorpha-with-the-description-of-a-new-species-of-sphyrapus-from-the-colombian-caribbean
#17
Andrés G Morales-Núñez, Catalina Morales-Ruiz, Néstor E Ardila
A new sphyrapodid tanaidacean, Sphyrapus caribensis sp. nov. is described and a new record of Kudinopasternakia siegi is reported for the Colombian Caribbean based on samples collected during cruises in 2014-2015. The new species appears to be most closely related to the northeast Atlantic species, Sphyrapus malleolus. Sphyrapus caribensis can be distinguished from Sphyrapus malleolus by a combination of characters, including the maxillipedal basis without long distal seta, the number of setae on the distoventral margin of pereopods 1 and 2, and the number of plumose seta on the pleopod basis...
2017: PeerJ
https://www.readbyqxmd.com/read/29069580/nicotinamide-prevents-sweet-beverage-induced-hepatic-steatosis-in-rats-by-regulating-the-g6pd-nadph-nadp-and-gsh-gssg-ratios-and-reducing-oxidative-and-inflammatory-stress
#18
Selene Ángeles Mejía, Luis Arturo Baiza Gutman, Clara Ortega Camarillo, Rafael Medina Navarro, Martha Catalina Sánchez Becerra, Leticia Damasio Santana, Miguel Cruz, Elizabeth Hernández Pérez, Margarita Díaz Flores
The disruption of redox state homeostasis, the overexpression of lipogenic transcription factors and enzymes, and the increase in lipogenic precursors induced by sweetened beverages are determinants of the development of nonalcoholic fatty liver disease. This study evaluated the action of nicotinamide (NAM) on the expression of glucose-6-phosphate dehydrogenase (G6PD) and redox, oxidative, and inflammatory states in a model of nonalcoholic hepatic steatosis induced by high and chronic consumption of carbohydrates...
October 22, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29066195/supplemental-feeding-and-other-anthropogenic-threats-to-green-turtles-chelonia-mydas-in-the-canary-islands
#19
Catalina Monzón-Argüello, Luis Cardona, Pascual Calabuig, María Camacho, José Luis Crespo-Picazo, Daniel García-Párraga, Santiago Mayans, Octavio P Luzardo, Jorge Orós, Nuria Varo-Cruz
Green turtles are found in the waters of the Canary Islands but little is known about the ecology and anthropogenic pressures that threaten them. Our results have revealed that juvenile green turtles, ranging in curve carapace length from 26.9-81.0cm, are regularly found in the archipelago and originate from rookeries in both the eastern and western Atlantic. Photo-identification and satellite tracking showed high levels of site fidelity to coastal foraging grounds associated with seagrass meadows, but stable isotope analysis indicated animal-based omnivorous diets after settlement on the continental shelf, with no increase in the consumption of macrophytes as the turtles grew...
October 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29065185/gonadal-cycle-of-corbicula-fluminea-bivalvia-corbiculidae-in-pampean-streams-southern-neotropical-region
#20
Luciana Cao, Cristina Damborenea, Pablo E Penchaszadeh, Gustavo Darrigran
Corbicula fluminea is an aggressive invasive species of bivalve that arrived into the Río de la Plata River between the late 60's and early 70's, and dispersed widely throughout the Neotropical region, evidencing a great adaptive flexibility to different environmental conditions. This species is a functional hermaphrodite with larval incubation inside the inner demibranch. Despite its widespread distribution, there are no previous studies of complete gonadal histology and reproductive cycle for this species in the Neotropical region...
2017: PloS One
keyword
keyword
110871
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"