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Malin Ericsson, Cecilia Lundholm, Stefan Fors, Anna K Dahl Aslan, Catalina Zavala, Chandra A Reynolds, Nancy L Pedersen
In this report we analyzed genetically informative data to investigate within-person change and between-person differences in late-life cognitive abilities as a function of childhood social class. We used data from nine testing occasions spanning 28 y in the Swedish Adoption/Twin Study of Aging and parental social class based on the Swedish socioeconomic index. Cognitive ability included a general factor and the four domains of verbal, fluid, memory, and perceptual speed. Latent growth curve models of the longitudinal data tested whether level and change in cognitive performance differed as a function of childhood social class...
June 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
Catalina Dussaillant, Guadalupe Echeverría, Jaime Rozowski, Nicolás Velasco, Antonio Arteaga, Attilio Rigotti
El huevo es un alimento que aporta proteína de alta calidad y numerosos nutrientes con potenciales beneficios para la salud. Sin embargo, la aparición de la enfermedad cardiovascular como importante causa de morbilidad y mortalidad en el mundo, junto con la identificación de los niveles elevados de colesterol plasmático como factor de riesgo para esta patología, llevó, en los años 70, a profesionales e instituciones de salud a limitar el consumo de colesterol y, por tanto, de huevo en la población. Hasta la fecha, los análisis de cohortes prospectivas tienden a mostrar que el consumo de hasta un huevo diario no aumenta significativamente el riesgo cardiovascular en la población sana...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Catalina Cabrera-Salcedo, Amy S Shah, Melissa Andrew, Leah Tyzinski, Vivian Hwa, Iris Gutmark-Little, Philippe Backeljauw, Andrew Dauber
The R183H mutation in the growth hormone gene (GH1) is a well-described genetic variant that causes autosomal dominant isolated growth hormone deficiency (IGHD) type II. Previous studies have demonstrated that individuals with this mutation have releasable growth hormone (GH) stores, but such release is severely impaired. Hess et al. reported variable height deficits (-4.5 to -1.0 SDS), variable IGF-I concentrations (-2.9 to -0.8 SDS), and low but detectable, or even normal stimulated peak GH in several patients with the R183H mutation...
June 19, 2017: Clinical Endocrinology
David K Y Lim, Holger Schuhmann, Skye R Thomas-Hall, Kenneth C K Chan, Taylor J Wass, Felipe Aguilera, T Catalina Adarme-Vega, Cristiana G O Dal'Molin, Glen J Thorpe, Jacqueline Batley, David Edwards, Peer M Schenk
To map out key lipid-related pathways that lead to rapid triacylglyceride accumulation in oleaginous microalgae, RNA-Seq was performed with Tetraselmis sp. M8 at 24h after exhaustion of exogenous nitrogen to reveal molecular changes during early stationary phase. Further gene expression profiling by quantitative real-time PCR at 16-72h revealed a distinct shift in expression of the fatty acid/triacylglyceride biosynthesis and β-oxidation pathways, when cells transitioned from log-phase into early-stationary and stationary phase...
June 6, 2017: Bioresource Technology
Rubén Corpas, Alberto M Hernández-Pinto, David Porquet, Catalina Hernández-Sánchez, Fatima Bosch, Arantxa Ortega-Aznar, Francesc Comellas, Enrique J de la Rosa, Coral Sanfeliu
Brain inflammaging is increasingly considered as contributing to age-related cognitive loss and neurodegeneration. Despite intensive research in multiple models, no clinically effective pharmacological treatment has been found yet. Here, in the mouse model of brain senescence SAMP8, we tested the effects of proinsulin, a promising neuroprotective agent that was previously proven to be effective in mouse models of retinal neurodegeneration. Proinsulin is the precursor of the hormone insulin but also upholds developmental physiological effects, particularly as a survival factor for neural cells...
June 14, 2017: Neuropharmacology
Catalina Ruiz-Cañada, Ángel Bernabé-García, Sergio Liarte, Carmen Luisa Insausti, Diego Angosto, José María Moraleda, Gregorio Castellanos, Francisco José Nicolás
Keratinocyte migration is a mandatory aspect of wound-healing. We have previously shown that Amniotic Membrane (AM) applied to chronic wounds assists healing through a process resulting in overexpression of c-Jun at the wound's leading edge. Also, we have demonstrated that amniotic membrane modifies the genetic program induced by TGF-ß in chronic wounds. In this paper, we used a scratch assay of Mv1Lu and HaCaT cells to examine the influence of AM application on the underlying signaling during scratch closure...
June 16, 2017: Journal of Tissue Engineering and Regenerative Medicine
Luis A Caicedo, Angie Sabogal, Oscar Serrano, Jorge I Villegas, Verónica Botero, María T Agudelo, Viviana Lotero, Diana Dávalos, Eliana Manzi, Ana M Aristizabal, Catalina Gomez, Gabriel J Echeverri
BACKGROUND: Hepatoblastoma is the most common primary malignant liver tumor in children and is usually diagnosed during the first 3 years of life. Overall survival has increased 50% due to chemotherapeutic schemes, expertise surgery centers, and liver transplantation. METHODS: A retrospective collection of data was performed from pediatric patients with diagnosis of hepatoblastoma. Variables included demographic, diagnostic tools and histological classification; chemotherapy and surgical treatment; and outcomes and patient survival...
June 2017: Transplantation Direct
Catalina Galeano-Garces, Emily T Camilleri, Scott M Riester, Amel Dudakovic, Dirk R Larson, Wenchun Qu, Jay Smith, Allan B Dietz, Hee-Jeong Im, Aaron J Krych, A Noelle Larson, Marcel Karperien, Andre J van Wijnen
OBJECTIVE: To determine the optimal environmental conditions for chondrogenic differentiation of human adipose tissue-derived mesenchymal stromal/stem cells (AMSCs). In this investigation we specifically investigate the role of oxygen tension and 3-dimensional (3D) culture systems. DESIGN: Both AMSCs and primary human chondrocytes were cultured for 21 days in chondrogenic media under normoxic (21% oxygen) or hypoxic (2% oxygen) conditions using 2 distinct 3D culture methods (high-density pellets and poly-ε-caprolactone [PCL] scaffolds)...
July 2017: Cartilage
Catalina Mansilla, Yannick Zondag, Hans Mulders, Piet Trompenaars
Focused electron beam induced deposition (FEBID) allows the creation of nanoscale structures through dissociation of an organo-metallic precursor by electrons at the beam impact point. The deposition of Pd can be interesting for its catalytic behavior and ability to contact carbon based materials. Two precursors were investigated - Pd(hfac)<sub>2</sub> and (Cp)Pd(allyl) - and two deposition methods: with and without an in-situ oxygen purification process. The deposition parameters can be tuned for the Pd(hfac)<sub>2</sub> precursor to provide a deposition with 23±2 at...
June 15, 2017: Nanotechnology
Antonela Martelli, Virginia Lo Russo, Gabriela Villares, Catalina T Pastor DE Ward
Two new free-living marine nematodes of the family Oxystominidae are described from San Antonio Bay (Río Negro) and San José Gulf (Chubut). Litinium australis sp. n., is characterized by having a rounded tail, by the first and second crown of cephalic setae with different lengths, gubernaculum with apophysis and by the presence of at least four precloacal papillae; Thalassoalaimus nestori sp. n., is characterized by having a conical tail, cephalic setae equal in length, gubernaculum with rounded and dorso-caudally directed apophysis and two precloacal papillae...
April 6, 2017: Zootaxa
Catalina Mosquera, Timothy L Fitzgerald, Haily Vora, Marysia Grzybowski
INTRODUCTION: The need for regional lymphadenectomy for treating appendiceal neuroendocrine tumors (A-NET) is determined by the risk of nodal metastasis. Current guidelines for A-NET are solely based on tumor size. Methods Patients with A-NET from 1988 to 2012 were identified from the SEER registry. The depth of invasion was defined as limited to the lamina propria (LP), invading the muscularis propria (MP), and through the serosa (TS). RESULTS: A total of 418 patients were included; the majority were female, white, and node-negative...
June 12, 2017: Journal of Surgical Oncology
Natalie Levtova, Luke M Healy, Catalina Marysol Carvajal Gonczi, Brandon Stopnicki, Manon Blain, Timothy E Kennedy, Craig S Moore, Jack P Antel, Peter J Darlington
Microglia provide immune surveillance within the brain and spinal cord. Various microglial morphologies include ramified, amoeboid, and pseudopodic. The link between form and function is not clear, especially for human adult microglia which are limited in availability for study. Here, we examined primary human microglia isolated from normal-appearing white matter. Pseudopodic and amoeboid microglia were effective phagocytes, taking up E. coli bioparticles using ruffled cell membrane sheets and retrograde transport...
May 22, 2017: Journal of Neuroimmunology
Catalina Sanchez-Alvarez, Oludamilola Oluleye, Joseph L Blackshear
No abstract text is available yet for this article.
June 6, 2017: Mayo Clinic Proceedings
W Porter McRoberts, Andrea Trescot, Leonardo Kapural, Catalina Apostol, Haleem Abdul
No abstract text is available yet for this article.
June 8, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Antoni Sureda, Silvia Tejada, Xavier Capó, Catalina Melià, Pere Ferriol, Samuel Pinya, Guillem Mateu-Vicens
The Mediterranean Sea is one of the most affected areas by the presence of invasive species. Halimeda incrassata (J Ellis) JV Lamoroux is newly arrived tropical seaweed in waters of the Mallorca Island (Balearic Islands, Western Mediterranean). The aim was to evaluate the effect of a potential competition between the invasive Halimeda incrassata, the native Posidonia oceanica and Dasycladus vermicularis, by means of antioxidant-related biomarkers in waters of Mallorca. The activities of the antioxidant enzymes-catalase, superoxide dismutase (SOD), glutathione peroxidase (GPx) and glutathione reductase (GRd)-, the levels of reduced glutathione (GSH) and malondialdehyde as indicator of lipid peroxidation were evaluated...
June 2, 2017: Science of the Total Environment
Luai Huleihel, Joseph Bartolacci, Jenna Lynn Dziki, Tatiana Vorobyov, Brooke Arnold, Michelle Scarritt, Catalina Pineda Molina, Samuel LoPresti, Bryan Brown, Stephen F Badylak
The early macrophage response to biomaterials has been shown to be a critical and predictive determinant of downstream outcomes. When properly prepared, bioscaffolds derived from mammalian extracellular matrix (ECM) have been shown to promote a transition in macrophage behavior from a pro-inflammatory to a regulatory/anti-inflammatory phenotype, which in turn has been associated with constructive and functional tissue repair. The mechanism by which ECM bioscaffolds promote this phenotypic transition, however, is poorly understood...
June 4, 2017: Tissue Engineering. Part A
Jesús Molina-Mula, Elizabeth Peter, Julia Gallo-Estrada, Catalina Perelló-Campaner
Most current management systems of healthcare institutions correspond to a model of market ethics with its demands of competitiveness. This approach has been called managerialism and is couched in terms of much-needed efficiencies and effective management of budgetary constraints. The aim of this study was to analyse the decision-making of nurses through the impact of health institution management models on clinical practice. Based on Foucault's ethical theory, a qualitative study was conducted through a discourse analysis of the nursing records in a hospital unit...
June 4, 2017: Nursing Inquiry
Alvaro de Bonilla-Damiá, Rosa Fernández-López, Victor M Pachón-Garrudo, Catalina Márquez-Vega, Isabel Borrego-Dorado
No abstract text is available yet for this article.
May 30, 2017: Medicina Clínica
Catalina Medrano-Galarza, Stephen J LeBlanc, Trevor J DeVries, Andria Jones-Bitton, Jeffrey Rushen, Anne Marie de Passillé, Derek B Haley
Dairy calves in North America traditionally are housed individually and fed by manual milk feeding (MMF) systems with buckets or bottles. Automated milk feeders (AMF) allow for more natural milk feeding frequencies and volumes, and calves are usually housed in groups. The objectives of this study were to (1) determine the prevalence of various milk-fed calf management and feeding practices and (2) compare these practices between dairy farms using MMF and AMF systems. A national online survey was performed from January to May 2015 to quantify management practices for the care of milk-fed dairy calves in Canada...
May 29, 2017: Journal of Dairy Science
Mario A Pagnotta, Juan A Fernández, Gabriella Sonnante, Catalina Egea-Gilabert
Understanding the distribution of genetic variations and accession structures is an important factor for managing genetic resources, but also for using proper germplasm in association map analyses and breeding programs. The globe artichoke is the fourth most important horticultural crop in Europe. Here, we report the results of a molecular analysis of a collection including globe artichoke and leafy cardoon germplasm present in the Italian, French and Spanish gene banks. The aims of this study were to: (i) assess the diversity present in European collections, (ii) determine the population structure, (iii) measure the genetic distance between accessions; (iv) cluster the accessions; (v) properly distinguish accessions present in the different national collections carrying the same name; and (vi) understand the diversity distribution in relation to the gene bank and the geographic origin of the germplasm...
2017: PloS One
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