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https://www.readbyqxmd.com/read/28081349/chrysin-prevents-brain-damage-caused-by-global-cerebralischemia-reperfusion-in-a-c57bl-j6-mouse-model
#1
Mehmet Akif Durak, Mustafa Namık Öztanır, Neşe Başak Türkmen, Osman Çiftçi, Aslı Taşlıdere, Mehmet Tecellioğlu, Arif Önder
BACKGROUND/AIM: The present study investigated the neuroprotective effects of chrysin (CRS) following global cerebral ischemia and reperfusion (I/R) in a C57BL/J6 mouse model. MATERIALS AND METHODS: A total of 40 mice were equally divided into four groups: (1) sham-operated (SH = control), (2) global cerebral I/R (I/R), (3) CRS, and (4) CRS + I/R. In the I/R group, the bilateral carotid arteries were clipped for 15 min and the mice were treated with vehicle (corn oil) for 10 days...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28081049/the-first-infant-death-associated-with-human-coronavirus-nl63-infection
#2
Capan Konca, Gulay Korukluoglu, Mehmet Tekin, Habip Almis, İbrahim Hakan Bucak, Hatice Uygun, Ayse Basak Altas, Fatma Bayrakdar
Human coronavirus NL63 (HCoV-NL63) primarily infects the upper respiratory tract. However, it may cause severe lower respiratory tract infection, and the clinical course may be severe in immunocompromised patients. To our knowledge, child death due to HCoV-NL63 has not been reported. We present a fatal lower respiratory tract disease associated with HCoV-NL63 in a 7-month-old malnourished infant.
February 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28080127/are-you-early-or-late-temporal-error-monitoring
#3
Başak Akdoğan, Fuat Balcı
Temporal judgments regarding a target interval typically produce a nearly normally distributed reproduction times centered on the target with substantial variance. This phenomenon indicates that the majority of our temporal judgments are deviations from the target times, which are assumed to originate from the underlying timing uncertainty. Although humans were found to adapt their decisions in response to timing uncertainty, we do not know if they can accurately judge the direction and degree of their temporal errors...
January 12, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28067684/diarrhea-after-allogeneic-stem-cell-transplantation-beyond-graft-versus-host-disease
#4
Katarzyna Robak, Joanna Zambonelli, Jaroslaw Bilinski, Grzegorz W Basak
Diarrhea constitutes a frequent and often debilitating complication of allogeneic hematopoietic cell transplantation (alloHCT). Especially when accompanied by jaundice, skin rash, and symptoms of the upper gastrointestinal tract, diarrhea strongly suggests emergence of acute graft-versus-host disease (GvHD), which is a serious immune complication of the procedure, with possible fatal consequences. However, especially when diarrhea occurs as an isolated symptom, the other causes must be excluded before initiation of GvHD treatment with immune-suppressive drugs...
January 6, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28052717/oncoplastic-surgery-volume-displacement-techniques-for-breast-conserving-surgery-in-patients-with-breast-cancer
#5
Gunay Gurleyik, Hikmet Karagulle, Esra Eris, Fugen Aker, Basak O Ustaalioglu
BACKGROUND: Surgical management of breast cancer has drastically changed. Breast-conserving surgery (BCS) has now become a commonly used method for its treatment. Oncoplastic techniques are widely applied with satisfactory aesthetic results. We evaluated the aesthetic and oncological outcomes of BCS with glandular tissue displacement techniques. METHODS: Seventy-five patients with invasive breast cancer were surgically treated by oncoplastic techniques. Preoperative evaluations, including breast and tumor size, localizations and features, were performed by physical examination, imaging methods, and histopathological analysis...
January 5, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28039980/effects-of-a-small-magnetic-field-on-homoclinic-bifurcations-in-a-low-prandtl-number-fluid
#6
Arnab Basak, Krishna Kumar
Effects of a uniform magnetic field on homoclinic bifurcations in Rayleigh-Bénard convection in a fluid of Prandtl number Pr = 0.01 are investigated using direct numerical simulations (DNS). A uniform magnetic field is applied either in the vertical direction or in the horizontal direction. For a weak vertical magnetic field, the possibilities of both forward and backward homoclinic bifurcations are observed leading to a spontaneous gluing of two limit cycles into one as well as a spontaneous breaking of a limit cycle into two for lower values of the Chandrasekhar's number ( Q≤5)...
December 2016: Chaos
https://www.readbyqxmd.com/read/28033514/infections-due-to-alphaherpesviruses-in-early-post-transplant-period-after-allogeneic-haematopoietic-stem-cell-transplantation-results-of-a-5-year-survey
#7
Maciej Przybylski, Anna Majewska, Tomasz Dzieciatkowski, Patrycja Rusicka, Grzegorz W Basak, Barbara Nasilowska-Adamska, Jaroslaw Bilinski, Wieslaw W Jedrzejczak, Marta Wroblewska, Kazimierz Halaburda, Grazyna Mlynarczyk, Agnieszka Tomaszewska
BACKGROUND: Infections caused by human α-herpesviruses usually have a benign course with recurrencies. However, they may become dangerous in immunocompromised hosts. In this case, molecular methods constitute a reliable diagnostic tool enabling rapid assessment of the efficacy of antiviral treatment strategies. OBJECTIVES: We estimated the frequency of alphaherpesviral DNAemia and the viral load during early post-transplantation period after alloHSCT; we also analyzed association of the DNAemia and chosen parameters of the patients...
December 21, 2016: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28029638/diagnostic-accuracy-and-safety-of-ct-guided-fine-needle-aspiration-biopsy-of-pulmonary-lesions-with-non-coaxial-technique-a-single-center-experience-with-442-biopsies
#8
Çağlar Uzun, Zehra Akkaya, Ebru Düşünceli Atman, Evren Üstüner, Elif Peker, Başak Gülpınar, Atilla Halil Elhan, Koray Ceyhan, Kayhan Çetin Atasoy
PURPOSE: We aimed to evaluate the diagnostic accuracy and safety of computed tomography (CT)-guided biopsy of pulmonary lesions with fine needle aspiration (FNA) using non-coaxial technique. METHODS: We analyzed 442 patients who underwent CT-guided lung biopsy with FNA and non-coaxial technique to determine the diagnostic outcomes, complication rates, and independent risk factors for diagnostic failure and pneumothorax. RESULTS: Diagnostic accuracy, sensitivity, and specificity were 97...
December 28, 2016: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/28017177/maintenance-of-balance-between-airway-pressure-and-intracranial-pressure-in-a-patient-with-tracheal-stenosis-undergoing-craniotomy-a-case-report
#9
Çiğdem Yıldırım Güçlü, Başak Ceyda Meço, Meltem Karamustafa, Yüksel Keçik
BACKGROUND AND OBJECTIVES: Tracheal stenosis is a rare but a life-threatening condition and anesthesia of a patient with tracheal stenosis is challenging for anesthesiologists. Maintaining stable hemodynamics and ventilation parameters are important issues in neuroanesthesia. Any increase in airway peak pressure and ETCO2 will result in increase in intracranial pressure which must be avoided during craniotomies. Tracheal stenosis could be a reason for increased airway pressure. CASE REPORT: We described a patient undergoing craniotomy with tracheal stenosis...
January 2017: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/28012929/schiff-base-poloxamer-p85-combination-demonstrates-chemotherapeutic-effect-on-prostate-cancer-cells-in-vitro
#10
Selami Demirci, Ayşegül Doğan, Neşe Başak Türkmen, Dilek Telci, Albert A Rizvanov, Fikrettin Şahin
Prostate cancer is a multistep and complicated cancer type that is regulated by androgens at the cellular level and remains the second commonest cause of death among men. Discovery and development of novel chemotherapeutic agents enabling rapid tumor cell death with minimal toxic effects to healthy tissues might greatly improve the safety of chemotherapy. The present study evaluates the anti-cancer activity of a novel heterodinuclear copper(II)Mn(II) complex (Schiff base) in combination with poly(ethylene oxide) and poly(propylene oxide) block copolymer (Pluronic) P85...
December 22, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28012153/zero-valent-zinc-nanoparticles-promote-neuroglial-cell-proliferation-a-biodegradable-and-conductive-filler-candidate-for-nerve-regeneration
#11
Umran Aydemir Sezer, Kevser Ozturk, Basak Aru, Gulderen Yanıkkaya Demirel, Serdar Sezer, Mehmet Recep Bozkurt
Regeneration of nerve, which has limited ability to undergo self-healing, is one of the most challenging areas in the field of tissue engineering. Regarding materials used in neuroregeneration, there is a recent trend toward electrically conductive materials. It has been emphasized that the capacity of conductive materials to regenerate such tissue having limited self-healing ability improves their clinical utility. However, there have been concerns about the safety of materials or fillers used for conductance due to their lack of degradability...
January 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28007678/use-of-probiotics-as-an-adjuvant-to-sequential-h-pylori-eradication-therapy-impact-on-eradication-rates-treatment-resistance-treatment-related-side-effects-and-patient-compliance
#12
Ayhan Hilmi Çekin, Yasin Şahintürk, Ferda Akbay Harmandar, Seyit Uyar, Başak Oğuz Yolcular, Yeşim Çekin
BACKGROUND/AIMS: To evaluate the effect of probiotics administered as an adjuvant to sequential Helicobacter pylori (H. pylori) eradication therapy on treatment outcome and patient compliance. MATERIALS AND METHODS: In total, 159 patients with H. pylori infection receiving sequential H. pylori eradication therapy were included in this randomized placebo-controlled study. Starting from day 0 of sequential eradication therapy (ERA), patients in the ERA+probiotic group [n=53, mean (SD) age: 47...
December 23, 2016: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/28005083/attenuating-effects-of-caffeic-acid-phenethyl-ester-with-intralipid-on-hepatotoxicity-of-chlorpyrifos-in-the-case-of-rats
#13
Recep Dokuyucu, Ali Bilgili, Basak Hanedan, Hatice Dogan, Ahmet Dokuyucu, Muhammed Murat Celik
BACKGROUND: Chlorpyrifos (CPF), insecticide widely used in agriculture, may cause poisonings in the case of humans. As a result, there is a large amount of treatment research underway to focus on the possibility of chlorpyrifos induced poisonings. The aim of this study has been to evaluate the effects of caffeic acid phenethyl ester (CAPE) and intralipid (IL) on hepatotoxicity induced by chlorpyrifos in the case of rats. MATERIAL AND METHODS: The rats in this study were treated with CPF (10 mg/kg body weight (b...
December 22, 2016: Medycyna Pracy
https://www.readbyqxmd.com/read/27998148/sb2s3-spiro-ometad-inorganic-organic-hybrid-p-n-junction-diode-for-high-performance-self-powered-photodetector
#14
Ashok Bera, Ayon Das Mahapatra, Sulakshana Mondal, Durga Basak
Organic-inorganic hybrid diodes are very promising for solution processing, low cost, high performance optoelectronic devices. Here, we report a high quality p-n heterojunction diode composed of n-type inorganic Sb2S3 and p-type organic 2,2',7,7'-tetrakis-(N,N-di-p-methoxyphenylamine)-9,9'-spirobifluorene (spiro-OMeTAD) with a rectification ratio of ∼10(2) at an applied bias of 1 V. On illumination with visible light (470 nm, 1.82 mW/cm(2)), the current value in our device becomes 8 × 10(2) times that of its dark value even at a zero bias condition...
December 21, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27989667/ser-422-phosphorylation-blocks-human-tau-cleavage-by-caspase-3-biochemical-implications-to-alzheimer-s-disease
#15
Priya Sandhu, Mansur Mohammad Naeem, Chunyu Lu, Premkumari Kumarathasan, James Gomes, Ajoy Basak
Proteolytic truncation of microtubule associated human (h) Tau protein by caspase-3 at the carboxy (C) terminus has been linked to the pathogenesis of Alzheimer's Disease (AD). This cleavage likely occurs between Asp(421)↓Ser(422) leading to the formation of 421-mer truncated Tau protein which has been found to be present as aggregate in high level after phosphorylation in mortal AD brain tissue compared to normal. At least 50 phosphorylation sites involving Ser, Thr and Tyr residues have been identified or proposed in hTau and a selected number of them have been implicated in hTau aggregation following latter's proteolytic truncation...
December 2, 2016: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/27965911/occipital-hypometabolism-on-fdg-pet-ct-scan-in-a-child-with-hodgkin-s-lymphoma
#16
Inci Uslu Biner, Ebru Tatci, Ozlem Ozmen, Atila Gokcek, Haci Ahmet Demir, Nadide Basak Gulleroglu
It is known that Fluorodeoxyglucose (FDG) Positron Emission/Computed Tomography (PET/CT) images may be helpful for evaluation of brain function in newborns. Here we described the fluorine-18 [18-F] FDG PET/CT imaging findings of encephalomalacia due to perinatal asphyxia in a child with refractory Hodgkin's Lymphoma (HL) who underwent PET/CT scan to stage the primary disease. Prominent hypometabolism was incidentally detected in the occipital regions bilaterally apart from the FDG uptakes in the malign lymphatic infiltrations...
2016: Case Reports in Radiology
https://www.readbyqxmd.com/read/27951681/two-component-fluorescent-semiconducting-hydrogel-from-naphthalene-diimide-appended-peptide-with-long-chain-amines-variation-in-thermal-and-mechanical-strengths-of-gels
#17
Nibedita Nandi, Shibaji Basak, Steven Kirkham, Ian W Hamley, Arindam Banerjee
Two-component fluorescent hydrogels have been discovered, containing the mixtures of naphthalene diimide (NDI)-conjugated peptide-functionalized bola-amphiphile and primary amines with long alkyl chains at physiological pH 7.46. The aggregation-induced enhanced emission associated with an NDI-appended peptide in aqueous medium is rare, as water is known to be a good quencher of fluorescence. In this study, an NDI-containing gelator peptide forms a highly fluorescent aggregate in aqueous medium. Absorption and emission spectroscopic techniques reveal the formation of J-aggregates among the chromophoric moieties in their aggregated state in aqueous medium...
December 13, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/27939219/induced-quiescence-of-lgr5-stem-cells-in-intestinal-organoids-enables-differentiation-of-hormone-producing-enteroendocrine-cells
#18
Onur Basak, Joep Beumer, Kay Wiebrands, Hiroshi Seno, Alexander van Oudenaarden, Hans Clevers
Lgr5+ adult intestinal stem cells are highly proliferative throughout life. Single Lgr5+ stem cells can be cultured into three-dimensional organoids containing all intestinal epithelial cell types at near-normal ratios. Conditions to generate the main cell types (enterocyte, goblet cells, Paneth cells, and M cells) are well established, but signals to induce the spectrum of hormone-producing enteroendocrine cells (EECs) have remained elusive. Here, we induce Lgr5+ stem cell quiescence in vitro by blocking epidermal growth factor receptor (EGFR) or mitogen-associated protein kinase (MAPK) signaling pathways in organoids and show that their quiescent state is readily reverted...
November 17, 2016: Cell Stem Cell
https://www.readbyqxmd.com/read/27937058/myxoid-leiomyosarcoma-of-the-cervix-a-case-report
#19
Serdar Kaya, Haluk Besim Bacanakgil, Zeynep Soyman, İsa Öz, Semiha Battal Havare, Basak Kaya
No abstract text is available yet for this article.
November 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27931595/transcatheter-closure-of-patent%C3%A2-ductus%C3%A2-arteriosus-in-extremely%C3%A2-premature%C3%A2-newborns-early-results-and-midterm-follow-up
#20
Evan M Zahn, Daniel Peck, Alistair Phillips, Phillip Nevin, Kaylan Basaker, Charles Simmons, Marion E McRae, Tracy Early, Ruchira Garg
OBJECTIVES: The goal of this study was to describe early and midterm outcomes of extremely premature newborns (EPNs) who underwent transcatheter echocardiographically guided patent ductus arteriosus (PDA) closure. BACKGROUND: Surgical ligation of PDA in EPNs confers significant risk for procedural morbidity and adverse long-term outcomes. METHODS: The Amplatzer Vascular Plug II was used in all cases. Post-ligation syndrome was defined using previously published parameters...
December 12, 2016: JACC. Cardiovascular Interventions
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