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https://www.readbyqxmd.com/read/28807527/does-ct-help-in-predicting-preepiglottic-space-invasion-in-laryngeal-carcinoma
#1
Gülpembe Bozkurt, Özlem Ünsal, İrfan Çelebi, Burak Ayhan, Umman Guliyev, Pınar Akova, Tülay Başak, Berna Uslu Coşkun
OBJECTIVE: Evaluating preepiglottic space involvement in laryngeal cancer by CT may lead misinterpretation. We sought to understand the causes of misinterpretation in evaluating the preepiglottic space by CT and assessed the effects of misinterpretation in treatment plans of patients with laryngeal squamous cell carcinomas. METHODS: Specimen histopathology reports of 102 (99 male, 3 female) patients who underwent total or partial laryngectomy due to supraglottic and/or transglottic laryngeal carcinoma were reviewed...
August 11, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28807445/the-accuracy-of-emergency-physician-performed-ultrasonography-as-a-diagnostic-tool-for-lateral-malleolar-fracture
#2
Pinar Ozturk, Ersin Aksay, Nese Colak Oray, Basak Bayram, Onur Basci, Duygu Tokgoz
OBJECTIVE: Many studies in the literature related to the investigation of the sensitivity and specificity of ultrasound examinations in lateral malleolar fractures is limited. The aim of this study is to investigate the sensitivity and specificity of ultrasound examinations performed by emergency physicians in fractures who are presented to the emergency department with blunt lateral malleolar trauma. METHOD: Patients over 18years of age who were admitted to the ED with lateral malleolar tenderness were enrolled to this study with convenience sampling...
August 7, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28799130/near-set-based-mucin-segmentation-in-histopathology-images-for-detecting-mucinous-carcinoma
#3
Soma Banerjee, Monjoy Saha, Indu Arun, Bijan Basak, Sanjit Agarwal, Rosina Ahmed, Sanjoy Chatterjee, Lipi B Mahanta, Chandan Chakraborty
This paper introducesnear-set based segmentation method for extraction and quantification of mucin regions for detecting mucinouscarcinoma (MC which is a sub type of Invasive ductal carcinoma (IDC)). From histology point of view, the presence of mucin is one of the indicators for detection of this carcinoma. In order to detect MC, the proposed method majorly includes pre-processing by colour correction, colour transformation followed by near-set based segmentation and post-processing for delineating only mucin regions from the histological images at 40×...
August 10, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28793828/the-predictive-factors-for-perceived-social-support-among-cancer-patients-and-caregiver-burden-of-their-family-caregivers-in-turkish-population
#4
Basak Oven Ustaalioglu, Ezgi Acar, Mecit Caliskan
OBJECTIVES: We aimed to identify the predictive factors for the perceived family social support among cancer patients and caregiver burden of their family caregivers. METHODS: Participants were 302 cancer patients and their family caregivers. Family social support scale was used for cancer patients, burden interview was used for family caregivers.All subjects also completed Beck depression invantery. The related socio-demographical factors with perceived social support (PSS) and caregiver burden were evaluated by correlation analysis...
August 9, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28789573/the-protective-effect-of-fish-oil-against-cisplatin-induced-eye-damage-in-rat
#5
Burcu Gul Baykalir, Osman Ciftci, Aslı Cetin, Nese Basak Turkmen
Ocular toxicity induced by anticancer chemotherapy is not uncommon, but underestimated and under-reported. Visual changes have been attributed to a number of chemotherapeutic agents in humans. Cisplatin (CP), a heavy metal compound, is used in the treatment of many types of tumors. CP is known to produce non-specific blurred vision, papilledema and optic neuritis for high doses as well as cumulative dose regimens. The aim of this study was to investigate the possible beneficial effects of fish oil (FO) on eye tissue oxidative status and histological alterations against CP-induced in the rats...
August 8, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28777542/1-4-dihydropyrrolo-3-2-b-pyrroles-as-a-single-component-photoactive-layer-a-new-paradigm-for-broadband-detection
#6
Ram Kumar Canjeevaram Balasubramanyam, Ahmad E Kandjani, Christopher J Harrison, Syed Sulthan Alaudeen Abdul Haroon Rashid, Ylias M Sabri, Suresh K Bhargava, Ramanuj Narayan, Pratyay Basak, Samuel J Ippolito
Single component organic photodetectors capable of broadband light sensing represent a paradigm shift for designing flexible and inexpensive optoelectronic devices. The present study demonstrates the application of a new quadrupolar 1,4-dihydropyrrolo[3,2-b]pyrrole derivative with spectral sensitivity across 350-830 nm as a potential broadband organic photodetector (OPD) material. The amphoteric redox characteristics evinced from the electrochemical studies are exploited to conceptualize a single component OPD with ITO and Al as active electrodes...
August 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28767457/comment-on-comparison-of-anterior-segment-optical-coherence-tomography-bleb-grading-moorfields-bleb-grading-system-and-intraocular-pressure-after-trabeculectomy
#7
Basak Can Ermerak, Mehmet Baykara, Hikmet Ozcetin
No abstract text is available yet for this article.
August 1, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28764328/protospacer-adjacent-motif-induced-allostery-activates-crispr-cas9
#8
Giulia Palermo, Clarisse G Ricci, Amendra Fernando, Rajshekhar Basak, Martin Jinek, Ivan Rivalta, Victor S Batista, J Andrew McCammon
CRISPR-Cas9 is a genome editing technology with major impact in life sciences. In this system, the endonuclease Cas9 generates double strand breaks in DNA upon RNA-guided recognition of a complementary DNA sequence, which strictly requires the presence of a protospacer adjacent motif (PAM) next to the target site. Although PAM recognition is essential for cleavage, it is unknown whether and how PAM binding activates Cas9 for DNA cleavage at spatially distant sites. Here, we find evidence of a PAM-induced allosteric mechanism revealed by microsecond molecular dynamics simulations...
August 7, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28763253/alda-1-protects-against-acrolein-induced-acute-lung-injury-and-endothelial-barrier-dysfunction
#9
Qing Lu, Miles Mundy, Eboni Chambers, Thilo Lange, Julie Newton, Diana Borgas, Hongwei Yao, Gaurav Choudhary, Rajshekhar Basak, Mahogany Oldham, Sharon Rounds
Inhalation of acrolein, a highly reactive aldehyde, causes lung edema. The underlying mechanism is poorly understood and there is no effective treatment. In this study, we demonstrated that acrolein not only dose-dependently induced lung edema, but also promoted lipopolysaccharide (LPS)-induced acute lung injury (ALI). Importantly, acrolein-induced lung injury were prevented and rescued by Alda-1, an activator of mitochondrial aldehyde dehydrogenase (ALDH) 2. Acrolein also dose-dependently increased monolayer permeability, disrupted adherens junctions and focal adhesion complexes, and caused intercellular gap formation in primary cultured lung microvascular endothelial cells (LMVEC); effects that were attenuated by Alda-1 and the antioxidant, N-acetylcysteine, but not by the NADPH inhibitor, apocynin...
August 1, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28762041/neuroinfluenza-evaluation-of-seasonal-influenza-associated-severe-neurological-complications-in-children-a-multicenter-study
#10
Muhammet Sukru Paksu, Kerim Aslan, Tanil Kendirli, Basak Nur Akyildiz, Nazik Yener, Riza Dincer Yildizdas, Mehmet Davutoglu, Ayhan Yaman, Sedat Isikay, Gulnar Sensoy, Haydar Ali Tasdemir
PURPOSE: Although influenza primarily affects the respiratory system, in some cases, it can cause severe neurological complications. Younger children are especially at risk. Pediatric literature is limited on the diagnosis, treatment, and prognosis of influenza-related neurological complications. The aim of the study was to evaluate children who suffered severe neurological manifestation as a result of seasonal influenza infection. METHODS: The medical records of 14 patients from six hospitals in different regions of the country were evaluated...
July 31, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28759274/fractional-carbon-dioxide-laser-for-facial-rejuvenation-a-prospective-study-to-evaluate-the-efficacy-and-the-safety
#11
Basak Yalici-Armagan, Gonca Elcin
BACKGROUND: The aim of this study was to evaluate the efficacy and safety of the fractional ablative carbon dioxide laser for facial rejuvenation. MATERIALS AND METHODS: Twenty-nine female who have the complaint of facial aging were recruited for the study. Participants received a maximum of 3 laser treatment sessions with one-month intervals and were scored using a 5-point scale on 7 categories for facial aging before and after the treatment by the physicians. Self assessments by participants were done at the last month of follow up period and 3 years after the last session...
July 31, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28750132/association-of-skin-thickness-with-alar-base-reduction-in-patients-undergoing-lateral-crural-repositioning-and-strut-grafting
#12
A Emre Ilhan, Tevfik Sozen, Basak Caypinar Eser, Betul Cengiz
Importance: Knowing the operation plan is important for rhinoplasty surgeons to prevent unpredictable results. Objectives: To investigate the frequency of alar base resection in patients with different skin thickness who underwent lateral crural repositioning and lateral crural strut graft and to evaluate the results in the context of the current literature. Design, Setting, and Participants: This retrospective case series study included 621 patients who underwent primary open septorhinoplasty by the same surgeon between January 1, 2012, and June 30, 2015...
July 27, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28745461/neonatal-perforated-appendicitis-in-incarcerated-inguinal-hernia-in-the-differential-diagnosis-of-testis-torsion
#13
Basak Erginel, Feryal Gun Soysal, Alaaddin Celik, Tansu Salman
Appendicitis in newborns is uncommon and difficult to diagnose. Reports on neonatal appendicitis subsequent to inguinal hernia incarceration are exceptionally rare. We present the case of a 26-day-old infant with perforated appendicitis due to incarceration of a right inguinal hernia, mimicking right testicular torsion.
July 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28735385/preparation-of-decellularized-liver-scaffolds-and-recellularized-liver-grafts
#14
Yibin Chen, Sharon Geerts, Maria Jaramillo, Basak E Uygun
Severe liver disease is the 12th leading cause of death in the USA, with organ transplantation often being the only viable option for treatment. However, due to the shortage of viable donor livers, it is estimated that over 1200 patients died in 2015 while waiting for liver transplantation. This highlights the need for alternative sources of viable organs. In this study, we describe a method that provides the groundwork for the development of functional liver grafts. The approach described here is for removal of cells from intact livers and subsequently repopulating them with functional liver cells...
July 23, 2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28735008/trehalose-induced-structural-modulation-of-bovine-serum-albumin-at-ambient-temperature
#15
Ahana Das, Pijush Basak, Rudradip Pattanayak, Turban Kar, Rajib Majumder, Debadrita Pal, Anindita Bhattacharya, Maitree Bhattacharyya, Samudra Prosad Banik
Trehalose is a well-known protein stabilizing osmolyte. The present study has been designed to understand the interaction of trehalose with BSA at ambient temperature. Steady state fluorescence and life-time analysis along with CD, DLS and ITC have been employed to show that trehalose causes surface-associated structural perturbation of BSA to promote its compaction. Trehalose at 0.1M concentration resulted in increased solvent exposure of one of the two tryptophans of BSA with a 5nm redshift in emission and enhanced susceptibility to acrylamide quenching with an increase in KSV from 2...
July 19, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28732942/decomposition-of-ppcps-by-ultrasound-assisted-advanced-fenton-reaction-a-case-study-with-salicylic-acid
#16
Başak Savun-Hekimoğlu, Nilsun H Ince
The study is about the degradation of a widely used pharmaceutical and personal care product-salicylic acid by sonocatalysis, and the experimental design of the reaction system. The first part of the study consists of sonication (572kHz) in the presence of zero-valent iron (ZVI) with or without H2O2 to select and optimize the operational parameters as frequency, time, initial solute concentration, dose of reagents and pH. The second part consists of the use of response surface methodology and multiple regression to develop an experimental design modeland to assess the individual and interactive effects of pH, power (Po), ZVI dose and H2O2...
November 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28720855/influence-of-cu-on-modifying-the-beta-phase-and-enhancing-the-mechanical-properties-of-recycled-al-si-fe-cast-alloys
#17
C B Basak, N Hari Babu
High iron impurity affects the castability and the tensile properties of the recycled Al-Si alloys due to the presence of the Fe containing intermetallic β-Al9Fe2Si2 phase. To date only Mn addition is known to transform the β-Al9Fe2Si2 phase in the Al-Si-Fe system. However, for the first time, as reported here, it is shown that β-phase transforms to the ω-Al7Cu2Fe phase in the presence of Cu, after solutionization at 793 K. The ω-phase decomposes below 673 K resulting into the formation of θ-Al2Cu phase...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28720234/effect-of-music-therapy-on-the-anxiety-levels-and-pregnancy-rate-of-women-undergoing-in-vitro-fertilization-embryo-transfer-a-randomized-controlled-trial
#18
Yilda Arzu Aba, Dilek Avci, Yilmaz Guzel, Semanur Kumral Ozcelik, Basak Gurtekin
PURPOSE: The aim of this study was to determine the effect of music therapy on the anxiety levels and pregnancy rates of women who underwent in vitro fertilization-embryo transfer. METHODS: This prospective randomized controlled trial was conducted with 186 infertile women who presented to the In Vitro Fertilization Unit at the American Hospital in Turkey between April 2015 and April 2016. The infertile women who met the inclusion criteria were assigned to the music therapy group or the standard therapy group through block randomization...
August 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/28717542/evaluation-of-postoperative-hydronephrosis-following-semirigid-ureteroscopy-incidence-and-predictors
#19
Mehmet İlker Gökçe, Barış Esen, Başak Gülpınar, Adil Hüseynov, Mete Özkidik, Evren Süer
OBJECTIVE: Hydronephrosis developing following ureteroscopy (URS) is an important issue associated with the long-term postoperative renal functions. Studies investigating the role of postoperative imaging revealed conflicting results. In this study, we aimed to determine the incidence and predictors of hydronephrosis following semirigid URS. MATERIAL AND METHODS: We evaluated the results of 455 patients who underwent U RS a nd postoperative imaging with non-contrast computed tomography (CT)...
June 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28699602/importance-of-target-calorie-intake-in-hospitalized-patients
#20
Ferda Akbay Harmandar, Ismail Gömceli, Başak Oğuz Yolcular, Ayhan Hilmi Çekin
BACKGROUND/AIMS: To evaluate the feasibility and clinical outcome of a nutritional algorithm based on target calorie intake commenced as enteral nutrition (EN) alone or in combination with supplemental parenteral nutrition (SPN) among hospitalized patients. MATERIALS AND METHODS: In total, 301 hospitalized patients who were provided with nutritional support, including EN (n=125) or EN+SPN (n=176), due to various medical conditions during their hospitalization were included in this study conducted at Antalya Training and Research Hospital...
July 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
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