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https://www.readbyqxmd.com/read/28340529/effects-of-rapid-thermal-annealing-and-different-oxidants-on-the-properties-of-laxalyo-nanolaminate-films-deposited-by-atomic-layer-deposition
#1
Chenxi Fei, Hongxia Liu, Xing Wang, Lu Zhao, Dongdong Zhao, Xingyao Feng
A comparative study of different sequences of two metal precursors [trimethylaluminum (TMA) and Tris(isopropylcyclopentadienyl) lanthanum (La((i)PrCp)3)] for atomic layer deposition (ALD) lanthanum aluminum oxide (LaxAlyO) films is carried out. The percentage compositions of C and N impurity of LaxAlyO films were investigated using in situ X-ray photoelectron spectroscopy (XPS). The effects of different oxidants on the physical and chemical properties and electrical characteristics of LaxAlyO films are studied before and after annealing...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28315152/bilateral-robotic-transabdominal-adrenalectomy-in-a-patient-with-intestinal-malrotation
#2
Zuliang Feng, Carmen C Solórzano
Bilateral adrenalectomy is the preferred surgical approach for patients with failed treatments for pituitary-based Cushing's syndrome. Intestinal malrotation (IM) is a rare congenital anatomic variant that rarely affects adults. The abnormal abdominal anatomy is concerning to surgeons planning elective procedures in such patients. Here, we describe a bilateral robotic transabdominal adrenalectomy (RTA) in a patient with IM. A 29-year-old female presented with refractory pituitary-based Cushing's syndrome and was found to have IM on preoperative CT scan...
March 17, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28291015/single-layer-of-ge-quantum-dots-in-hfo-sub-2-sub-for-floating-gate-memory-capacitors
#3
Ana-Maria Lepadatu, Catalin Palade, Adrian Slav, Adrian Valentin Malaroiu, Sorina Lazanu, Toma Stoica, Constantin Logofatu, Valentin Teodorescu, Magdalena Lidia Lidia Ciurea
High performance trilayer memory capacitors with a floating gate of a single layer of Ge quantum dots (QDs) in HfO<sub>2</sub> were fabricated using magnetron sputtering followed by rapid thermal annealing (RTA). The layer sequence of capacitor is gate HfO<sub>2</sub>/ floating gate of single layer of Ge QDs in HfO<sub>2</sub>/ tunnel HfO<sub>2</sub>/ p-Si wafers. Both Ge and HfO<sub>2</sub> are nanostructured by RTA at moderate temperatures of 600 - 700 <sup>o</sup>C...
March 14, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28287622/a-codon-shuffling-method-to-prevent-reversion-during-production-of-replication-defective-herpesvirus-stocks-implications-for-herpesvirus-vaccines
#4
Gang Li, Charles Ward, Rukhsana Yeasmin, Steven Skiena, Laurie T Krug, J Craig Forrest
Herpesviruses establish life-long chronic infections that place infected hosts at risk for severe disease. Herpesvirus genomes readily undergo homologous recombination (HR) during productive replication, often leading to wild-type (WT) reversion during complementation of replication-defective and attenuated viruses via HR with the helper gene provided in trans. To overcome this barrier, we developed a synthetic-biology approach based on a technique known as codon shuffling. Computer-assisted algorithms redistribute codons in a helper gene, thereby eliminating regions of homology, while enabling manipulation of factors such as codon-pair bias and CpG content to effectively titrate helper-gene protein levels...
March 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28267369/compound-elevated-skull-fractures-review-of-literature
#5
G Lakshmi Prasad, N Anmol
INTRODUCTION: Compound elevated skull fractures (CESF) are rare traumatic injuries. To date, only 27 cases have been reported. METHODS: The authors report three cases of CESF managed at their institute. All were middle-aged males. The mechanism was assault by sharp-edged objects in two and road traffic accident (RTA) in one case. One underwent simple suturing; debridement and decompressive craniectomy was done in the remaining two cases. Good and poor outcomes were noted in one case each, while one died...
March 7, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28230053/ricin-uses-arginine-235-as-an-anchor-residue-to-bind-to-p-proteins-of-the-ribosomal-stalk
#6
Yijun Zhou, Xiao-Ping Li, Brian Y Chen, Nilgun E Tumer
Ricin toxin A chain (RTA) binds to stalk P-proteins to reach the α-sarcin/ricin loop (SRL) where it cleaves a conserved adenine. Arginine residues at the RTA/RTB interface are involved in this interaction. To investigate the individual contribution of each arginine, we generated single, double and triple arginine mutations in RTA. The R235A mutation reduced toxicity and depurination activity more than any other single arginine mutation in yeast. Further reduction in toxicity, depurination activity and ribosome binding was observed when R235A was combined with a mutation in a nearby arginine...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28228591/the-swi-snf-chromatin-regulator-brg1-modulates-the-transcriptional-regulatory-activity-of-the-ebv-dna-polymerase-processivity-factor-bmrf1
#7
Mei-Tzu Su, Ya-Ting Wang, Yen-Ju Chen, Su-Fang Lin, Ching-Hwa Tsai, Mei-Ru Chen
During lytic phase of Epstein-Barr virus (EBV), binding of the transactivator Zta to the origin of lytic replication (oriLyt) and the BHLF1 transcript, forming a stable RNA-DNA hybrid, are required to initiate viral DNA replication. EBV-encoded viral DNA replication proteins form complexes to amplify viral DNA. BMRF1, the viral DNA polymerase accessory factor, is essential for lytic DNA replication and also known as a transcriptional regulator of the expression of BHLF1 and BALF2 (ssDNA-binding protein). In order to determine systematically how BMRF1 regulates viral transcription, a BMRF1 knockout bacmid was generated to analyze viral gene expression using a viral DNA microarray...
February 22, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28226006/hospitalization-due-to-road-traffic-injuries-in-brazil-2013-hospital-stay-and-costs
#8
Silvânia Suely Caribé de Araújo Andrade, Maria Helena Prado de Mello Jorge
Objetivo: to describe hospitalization rates and to estimate hospital costs and time spent in hospital due to road traffic accidents (RTA) in Brazil, in 2013. Methods: this is an ecological study conducted using data from the Brazilian National Hospital Information System. Results: in 2013, 170,805 hospitalizations due to RTA were funded by the Brazilian National Health System; 78.2% of the individuals were male, 48.6% were from 20 to 39 years old, and 51...
January 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28217583/profile-of-trauma-patients-in-the-emergency-department-of-a-tertiary-care-hospital-in-south-india
#9
Kundavaram Paul Prabhakar Abhilash, Nilanchal Chakraborthy, Gautham Raja Pandian, Vineet Subodh Dhanawade, Thomas Kurien Bhanu, Krishna Priya
BACKGROUND: Trauma is an increasing cause of morbidity and mortality in India. This study was done to improve the understanding of the mode of trauma, severity of injuries, and outcome of trauma victims in our hospital. MATERIALS AND METHODS: This was a retrospective observational study of all adult trauma patients more than 18-year-old presenting to our emergency department (ED). Details of the incident, injuries, and outcome were noted. RESULTS: The ED attended to 16,169 patients during the 3-month study period with 10% (1624/16,169) being adult trauma incidents...
July 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28212352/rta-occupancy-of-the-origin-of-lytic-replication-during-murine-gammaherpesvirus-68-reactivation-from-b-cell-latency
#10
Alexis L Santana, Darby G Oldenburg, Varvara Kirillov, Laraib Malik, Qiwen Dong, Roman Sinayev, Kenneth B Marcu, Douglas W White, Laurie T Krug
RTA, the viral Replication and Transcription Activator, is essential for rhadinovirus lytic gene expression upon de novo infection and reactivation from latency. Lipopolysaccharide (LPS)/toll-like receptor (TLR)4 engagement enhances rhadinovirus reactivation. We developed two new systems to examine the interaction of RTA with host NF-kappaB (NF-κB) signaling during murine gammaherpesvirus 68 (MHV68) infection: a latent B cell line (HE-RIT) inducible for RTA-Flag expression and virus reactivation; and a recombinant virus (MHV68-RTA-Bio) that enabled in vivo biotinylation of RTA in BirA transgenic mice...
February 16, 2017: Pathogens
https://www.readbyqxmd.com/read/28209030/effects-of-annealing-ambient-on-the-characteristics-of-laalo3-films-grown-by-atomic-layer-deposition
#11
Lu Zhao, Hong-Xia Liu, Xing Wang, Chen-Xi Fei, Xing-Yao Feng, Yong-Te Wang
We investigated the effects of different annealing ambients on the physical and electrical properties of LaAlO3 films grown by atomic layer deposition. Post-grown rapid thermal annealing (RTA) was carried out at 600 °C for 1 min in vacuum, N2, and O2, respectively. It was found that the chemical bonding states at the interfacial layers (ILs) between LaAlO3 films and Si substrate were affected by the different annealing ambients. The formation of IL was enhanced during the RTA process, resulting in the decrease of accumulation capacitance, especially in O2 ambient...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28194236/european-union-directive-2014-85-eu-on-driver-licensing-in-obstructive-sleep-apnoea-early-experiences-with-its-application-in-the-uk
#12
EDITORIAL
Dipansu Ghosh, Thomas W Mackay, Renata L Riha
OSA patients' risk of RTA should be assessed using detailed driving history with specific focus on "red flags" http://ow.ly/mxPi305isni.
September 2016: Breathe
https://www.readbyqxmd.com/read/28187203/preliminary-study-on-alterations-of-altitude-road-traffic-in-china-from-2006-to-2013
#13
Hui Zhao, Zhiyong Yin, Hongyi Xiang, Zhikang Liao, Zhengguo Wang
INTRODUCTION: Road traffic can play an important role in strengthening regional economic activities, especially at high altitude, and it is necessary to know important traffic-related information. Although previous studies reported on road traffic in China, there has been little research on high-altitude road traffic to date. METHOD: The annual official census of road traffic safety from 2006 to 2013 was used to obtain data on the general population, registered drivers, registered vehicles, newly built roads, road traffic accidents (RTAs), mortality rate per 100 000 populations and per 10 000 vehicles in high-altitude provinces, including Tibet, Qinghai, Xinjiang, Gansu, Yunnan, Sichuan, and Chongqing...
2017: PloS One
https://www.readbyqxmd.com/read/28180125/relationship-between-air-pollution-weather-traffic-and-traffic-related-mortality
#14
Maryam Dastoorpoor, Esmaeil Idani, Narges Khanjani, Gholamreza Goudarzi, Abbas Bahrampour
BACKGROUND: Air pollution and weather are just two of many environmental factors contributing to traffic accidents (RTA). OBJECTIVES: This study assessed the effects of these factors on traffic accidents and related mortalities in Ahvaz, Iran. METHODS: In this ecological study, data about RTA, traffic-related mortalities, air pollution (including NO, CO, NO2, NOx PM10, SO2, and O3 rates) and climate data from March 2008 until March 2015 was acquired from the Khuzestan State Police Force, the Environmental Protection Agency and the State Meteorological Department...
September 2016: Trauma Monthly
https://www.readbyqxmd.com/read/28170055/patients-with-alcohol-use-disorder-initial-results-from-a-prospective-multicenter-registry-in-the-spanish-network-on-addiction-disorders-cohrta-study
#15
Arantza Sanvisens, Paola Zuluaga, Inmaculada Rivas, Gabriel Rubio, Antoni Gual, Marta Torrens, Antoni Short, Francisco Javier Álvarez, Jordi Tor, Magí Farré, Fernando Rodríguez de Fonseca, Roberto Muga
The Alcohol Program of the Spanish Network on Addictive Disorders-RTA requires a longitudinal study to address different research questions related to alcoholism. The cohort study (CohRTA) focuses on patients seeking treatment for alcohol use disorder, as a multicentre, collaborative research project aimed to improve secondary prevention and early diagnosis of pathological processes associated with the disorder. METHODS: multicentre cohort study in adults (>18 years) seeking their first treatment of the disorder...
January 12, 2017: Adicciones
https://www.readbyqxmd.com/read/28165040/lead-free-piezoelectrics-v-3-to-v-5-ion-conversion-promoting-the-performances-of-v-doped-zinc-oxide
#16
M Laurenti, M Castellino, D Perrone, A Asvarov, G Canavese, A Chiolerio
Vanadium doped ZnO (VZO) thin films were grown by RF magnetron sputtering, starting from a ZnO:V ceramic target. The crystal structure, chemical composition, electric and piezoelectric properties of the films were investigated either on the as-grown thin films or after a post-deposition rapid thermal annealing (RTA) treatment performed at 600 °C for different lengths of time (1 and 5 min) in an oxygen atmosphere. Substitutional doping of Zn(2+) with V(3+) and V(5+) ions strongly deteriorated the hexagonal wurtzite ZnO structure of the as-grown thin films due to lattice distortion...
February 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28159615/immobilization-of-r-%C3%AF-transaminase-on-mno2-nanorods-for-catalyzing-the-conversion-of-r-1-phenylethylamine
#17
Jian Sun, Wen-Hui Cui, Kun Du, Qian Gao, Mengmeng Du, Peijun Ji, Wei Feng
R-ɷ-transaminases transfer an amino group from an amino donor (e.g. (R)-1-phenylethylamine) onto an amino acceptor (e.g. pyruvate), resulting a co-product (e.g. d-alanine). This work intends to immobilize R-ɷ-Transaminase on MnO2 nanorods to achieve multienzyme catalysis. R-ɷ-Transaminase (RTA) and d-amino acid oxidase (DAAO) have been fused to an elastin-like polypeptide (ELP) separately through genetic engineering of the enzymes. ELP-RTA and ELP-DAAO have been separately immobilized on polydopamine-coated MnO2 nanorods...
March 10, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28127482/successful-management-of-refractory-type-1-renal-tubular-acidosis-with-amiloride
#18
Patrick Oguejiofor, Robert Chow, Kenneth Yim, Bernard G Jaar
A 28-year-old female with history of hypothyroidism, Sjögren's Syndrome, and Systemic Lupus Erythematosus (SLE) presented with complaints of severe generalized weakness, muscle pain, nausea, vomiting, and anorexia. Physical examination was unremarkable. Laboratory test showed hypokalemia at 1.6 mmol/l, nonanion metabolic acidosis with HCO3 of 11 mmol/l, random urine pH of 7.0, and urine anion gap of 8 mmol/l. CT scan of the abdomen revealed bilateral nephrocalcinosis. A diagnosis of type 1 RTA likely secondary to Sjögren's Syndrome was made...
2017: Case Reports in Nephrology
https://www.readbyqxmd.com/read/28118409/epigenetic-landscape-of-kaposi-s-sarcoma-associated-herpesvirus-genome-in-classic-kaposi-s-sarcoma-tissues
#19
Rui Sun, Xiaohua Tan, Xing Wang, Xiaodong Wang, Lei Yang, Erle S Robertson, Ke Lan
Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically related to Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD). It typically displays two different phases in its life cycle, the default latency and occasional lytic replication. The epigenetic modifications are thought to determine the fate of KSHV infection. Previous studies elegantly depicted epigenetic landscape of latent viral genome in in vitro cell culture systems. However, the physiologically relevant scenario in clinical KS tissue samples is unclear...
January 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28116670/an-inducible-crispr-on-system-for-controllable-gene-activation-in-human-pluripotent-stem-cells
#20
Jianying Guo, Dacheng Ma, Rujin Huang, Jia Ming, Min Ye, Kehkooi Kee, Zhen Xie, Jie Na
Human pluripotent stem cells (hPSCs) are an important system to study early human development, model human diseases, and develop cell replacement therapies. However, genetic manipulation of hPSCs is challenging and a method to simultaneously activate multiple genomic sites in a controllable manner is sorely needed. Here, we constructed a CRISPR-ON system to efficiently upregulate endogenous genes in hPSCs. A doxycycline (Dox) inducible dCas9-VP64-p65-Rta (dCas9-VPR) transcription activator and a reverse Tet transactivator (rtTA) expression cassette were knocked into the two alleles of the AAVS1 locus to generate an iVPR hESC line...
January 23, 2017: Protein & Cell
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