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Low birth weight

Ivonne Ramirez-Silva, Juan A Rivera, Belem Trejo-Valdivia, Aryeh D Stein, Reynaldo Martorell, Isabelle Romieu, Albino Barraza-Villarreal, Laura Avila-Jiménez, Usha Ramakrishnan
Background: Rapid early weight gain has been associated with increased risk of obesity and cardiometabolic alterations, but evidence in low and middle-income countries is inconclusive. Objective: We evaluated the relation between relative weight gain from 1 to 48 mo with adiposity and cardiometabolic risk factors at 4-5 y of age, and determined if adiposity is a mediator for cardiometabolic alterations. Methods: We studied 428 Mexican children with anthropometric and blood pressure (BP) information from birth to 5 y of age from POSGRAD (Prenatal Omega-3 fatty acid Supplementation and child GRowth And Development), of whom 334 provided measures of adiposity and cardiometabolic risk markers at 4 y...
June 19, 2018: Journal of Nutrition
Emily Heidenreich, Robert Johnson, Barbara Sargent
PURPOSE: To systematically review the recent evidence on physical therapy (PT) diagnosis, prognosis, and intervention of congenital muscular torticollis to inform the update to the PT management of congenital muscular torticollis evidence-based clinical practice guideline. METHODS: From 2012 to 2017, 7 databases were searched for studies that informed PT diagnosis, prognosis, or intervention of infants and children with congenital muscular torticollis. Studies were appraised for risk of bias and quality...
July 2018: Pediatric Physical Therapy
Christopher M Runyan, Armando Uribe-Rivera, Shahryar Tork, Tasneem A Shikary, Zarmina Ehsan, K Nicole Weaver, Md Monir Hossain, Christopher B Gordon, Brian S Pan
Background: Pierre Robin sequence (PRS)-related airway obstruction is often treated surgically; however, objective measures predicting the need for surgery are poorly defined. Methods: A retrospective chart review was performed on 171 neonates with PRS. Infants were grouped based upon intervention modality: nonsurgical (conservative) or surgical [mandibular distraction osteogenesis (MDO) or tracheostomy]. Demographic data, physical examination findings, and study results were compared between groups to determine risk factors for surgical intervention, and to predict long-term success or failure of those interventions...
May 2018: Plastic and Reconstructive Surgery. Global Open
Hua He, Anne Monique Nuyt, Zhong-Cheng Luo, Francois Audibert, Lise Dubois, Shu-Qin Wei, Haim A Abenhaim, Emmanuel Bujold, Isabelle Marc, Pierre Julien, William D Fraser
Small for gestational age (SGA) infants are at increased risk of type 2 diabetes in adulthood. It is unknown whether any prenatal biomarkers are helpful for identifying SGA infants with altered metabolic health profile at birth or later life. In a nested study of 162 SGA (birth weight < 10th percentile) and 161 optimal birth weight (25th-75th percentiles) control infants in the 3D (design, develop and discover) birth cohort in Canada, we assessed whether maternal circulating placental growth factor (PlGF), a biomarker of placental function, is associated with metabolic health biomarkers in SGA infants...
2018: Frontiers in Endocrinology
Shalu R Chaudhary, Samarth Govil, Mrudula K Lala, Hardik B Yagnik
BACKGROUND: Infant and young child feeding (IYCF) practices are multidimensional and change rapidly in short intervals in the 1st year of life, asking for simultaneous assessment of various feeding dimensions in children of 6 months and older. Infant and Child Feeding Index (ICFI) is a composite index which measures complete feeding practices for infants and young children. The present study was conducted to assess IYCF practices for children aged 6-36 months in terms of ICFI and some sociodemographic factors and find out the association of ICFI with nutritional status...
May 2018: Journal of Family & Community Medicine
Gifty Dufie Ampofo, Harry Tagbor, Imelda Bates
BACKGROUND: The burden of malaria and anaemia in pregnancy remains high despite the availability of proven efficacious antenatal care interventions. Sub-optimal uptake of the interventions may be due to inadequate active participation of pregnant women in their antenatal care. It was hypothesized that providing opportunities for pregnant women to improve upon active participation in their antenatal care through malaria and anaemia point-of-care testing would improve adherence to ANC recommendations and interventions and lead to better pregnancy outcomes...
June 19, 2018: Malaria Journal
Saranya Ravichandran, Nitin Shashikant Chouthai, Bhavyata Patel, Amit Sharma, Avanti Gupte, Mia Michelle Ma, Divya Mamilla, Mirjana Lulic Botica, Ronald Thomas, Deepak Kamat
AIM: We determined the influence of cumulative dosing of caffeine citrate on the neurodevelopmental outcomes of low birth weight (VLBW) infants at 18-22 months of postmenstrual age. METHODS: This retrospective chart analysis was conducted at Detroit Medical Center, Michigan, USA. The 181 infants we included were born between January 2006 and December 2016, were less than 32 weeks of gestational age and weighed less than 1,500 grams. Data on their perinatal and postnatal characteristics were retrieved from their medical records and they were assessed using the Bayley Scales of Infant Development - Third Edition...
June 19, 2018: Acta Paediatrica
Atsushi Uchiyama, Hirokazu Watanabe, Hidehiko Nakanishi, Satsuki Totsu
OBJECTIVE: Delayed thyrotropin (TSH) elevation (dTSHe) is common in low birthweight infants. We aimed to clarify the risk factors for the development of dTSHe in infants weighing <2000 g at birth. PATIENTS AND METHODS: According to Japanese guidelines, infants with birthweight <2000 g underwent second capillary TSH screening within 30 days, either at one month of age; or when weight reached 2.5 kg; or at discharge. dTSHe was defined as TSH >20 mIU/L by venous sampling following a normal result (<15 mIU/L) at first screening aged 4-6 days...
June 19, 2018: Clinical Endocrinology
Anu Rammohan, Srinivas Goli, Deepti Singh, Dibyasree Ganguly, Uma Singh
India has the highest proportion of low birth weight (LBW) babies born in the developing world. Poor maternal nutrition during pregnancy is associated with adverse infant health outcomes. The main objective of this paper was to assess the socioeconomic factors associated with dietary diversity among pregnant women and to investigate the association between maternal dietary diversity and LBW among their babies. The data for these analyses were derived from a survey conducted in November and December, 2014 among 230 women who had newly delivered in hospitals in Uttar Pradesh, the largest Indian state which has the poorest maternal outcomes in the country...
June 19, 2018: Women & Health
Li-Juan Sun, Gu-Feng Xu, Min Lv, Hao Zhou, He-Feng Huang, Qiong Luo
BACKGROUND: In clinical practice, abnormal biochemical changes often occur in women who eventually develop preeclampsia (PE). The study aims to investigate whether maternal serum biochemical markers in the early third trimester can predict PE and neonatal birth weight. STUDY DESIGN: A retrospective case-control study was performed on 287 women who subsequently developed PE (mild = 139; severe = 148) and 143 healthy women. Fasting venous blood samples of all gravidas were drawn for routine biochemical markers screening in the early third trimester (28...
June 19, 2018: Journal of Women's Health
L Li, X Zhang, S-L Hong, Y Chen, G-H Ren
OBJECTIVE: Preeclampsia (PE) is an important disease affecting maternal and neonatal pregnancy. Long non-coding RNA plays an important role in preeclampsia. This study aims to explore the role of HOXA distal transcript antisense RNA (HOTTIP) in preeclampsia. PATIENTS AND METHODS: The expression of HOTTIP in placentas of preeclampsia and normal pregnancy was detected by polymerase chain reaction (PCR). The difference of clinical data between high expression HOTTIP group and low expression HOTTIP group was compared to explore the relationship between HOTTIP and the progress of preeclampsia...
June 2018: European Review for Medical and Pharmacological Sciences
Juyoung Lee, Mee Hong, Sook Kyung Yum, Jung Hyun Lee
PURPOSE: Severe acidosis is one of the strongest predictors of neurologic outcomes in full-term infants with suspected hypoxic-ischemic encephalopathy. However, the relative importance of acidosis as a predictor of outcomes in preterm infants is much less clear. The goals of the present study were to examine the association between postnatal acidosis and severe intraventricular hemorrhage (IVH) and to establish a new score model including acid-base status after birth for predicting the risk of this morbidity...
June 18, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Arun Fotedar, Jasjit Singh Bhasin, Ashok Chakravarty, Avinash Kulkarni, Gaurav Bhalla, Fahmina Anwar, Shashidhar Rao
Introduction: Iron deficiency anemia represents 3rd largest disease burden, with an estimated 6.9 billion disability-adjusted life years. Iron-fortified cereals (IFIC) can contribute substantially in preventing iron deficiency anemia and maintaining an adequate body iron status. The aim of this study is to assess the effectiveness of IFIC intake along with other complementary food/s on the hemoglobin (hb) level of children from 12 to 24 months of age. Materials and Methods: A cross-sectional study was conducted from November 2015 to February 2016 in three pediatric outpatient clinics of New Delhi, India...
January 2018: Journal of Family Medicine and Primary Care
Lilian Cássia Bórnia Jacob-Corteletti, Eliene Silva Araújo, Josilene Luciene Duarte, Fernanda Zucki, Kátia de Freitas Alvarenga
Purpose: The aims of the study were to examine the acoustic reflex screening and threshold in healthy neonates and those at risk of hearing loss and to determine the effect of birth weight and gestational age on acoustic stapedial reflex (ASR). Method: We assessed 18 healthy neonates (Group I) and 16 with at least 1 risk factor for hearing loss (Group II); all of them passed the transient evoked otoacoustic emission test that assessed neonatal hearing. The test battery included an acoustic reflex screening with activators of 0...
June 18, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
Areti Angeliki Veroniki, Jesmin Antony, Sharon E Straus, Huda M Ashoor, Yaron Finkelstein, Paul A Khan, Marco Ghassemi, Erik Blondal, John D Ivory, Brian Hutton, Kevin Gough, Brenda R Hemmelgarn, Erin Lillie, Afshin Vafaei, Andrea C Tricco
BACKGROUND: Nearly all newly infected children acquire Human Immunodeficiency virus (HIV) via mother-to-child transmission (MTCT) during pregnancy, labour or breastfeeding from untreated HIV-positive mothers. Antiretroviral therapy (ART) is the standard care for pregnant women with HIV. However, evidence of ART effectiveness and harms in infants and children of HIV-positive pregnant women exposed to ART has been largely inconclusive. The aim of our systematic review and network meta-analysis (NMA) was to evaluate the comparative safety and effectiveness of ART drugs in children exposed to maternal HIV and ART (or no ART/placebo) across different study designs...
2018: PloS One
Dipti Sarma, Uma K Saikia, Darvin V Das
Context: The neonatal skeletal outcomes due to maternal Vitamin D deficiency. Aims: The aim of this study is to assess the serum 25 hydroxy Vitamin D (25[OH]D) status in pregnant women and correlate with cord blood 25(OH)D levels, femur length at 34 weeks gestation, and neonatal anthropometry (birth weight, birth length, and head circumference). Settings and Design: This was prospective cohort study. Subjects and Methods: This study was carried out in 250 healthy primigravida between 18 and 40 years of age in the third trimester of gestation attending the Obstetrics and Gynaecology Department of Gauhati Medical College, Guwahati from December 2012 to December 2015...
March 2018: Indian Journal of Endocrinology and Metabolism
Po-Ming Wu, Hsin-I Shih, Wen-Hao Yu, Li-Wen Chen, Lie-Chuan Wang, Chao-Ching Huang, Yi-Fang Tu
BACKGROUND: The neonatal changes of corpus callosum or cerebellar volume in preterm infants have been shown to link with abnormal mentality and motor disability in early childhood. This study aims to predict the long-term neurological outcomes by measuring these changes on neonatal brain ultrasound in preterm infants. METHODS: Our cohort consisted of infants aged below 32 weeks' gestation with very low birth body weights who completed neuro-assessments at 5 years of age...
June 1, 2018: Pediatrics and Neonatology
István Gera
Data from epidemiological and clinical studies published in the past two decades indicate certain association between periodontal disease and increased risk for preterm birth or low birth weight. Although the strength of those observed associations is weak, periodontitis today is considered as one of the potentially modifiable risk factors for adverse pregnancy outcomes. The aims of the publication are to summarize the epidemiological and clinical evidence for the impact of periodontal disease on adverse pregnancy outcomes and to make an attempt to overview the potential biological mechanism behind this association...
June 2018: Orvosi Hetilap
S De Carolis, A Botta, Gelsomina Del Sordo, R Guerrisi, S Salvi, M P De Carolis, A Iaconelli, P Giustacchini, M Raffaelli, A Lanzone
BACKGROUND: Pregnancy after bariatric surgery (BS) has an increased risk for small-for-gestational-age infants (SGA), shorter length of gestation, and probably perinatal mortality. The aim of this study was to investigate if biliopancreatic diversion could impair pregnancy outcomes in comparison to other bariatric surgery procedures. METHODS: We conducted a cohort retrospective single-center study in 65 women before and after BS. Thirty-one pregnancies occurred before BS, while 109 after BS, amongst which n = 51 after biliopancreatic diversion (BPD) and n = 58 after non-malabsorptive procedures...
June 16, 2018: Obesity Surgery
DengLiang Wang, Quan Kang, ShuJun Shi, Wei Hu
To summarize the clinical characteristics, diagnosis, treatment and prognosis among 152 children with annular pancreas (AP). A retrospective review of 152 patients with AP who were treated with surgical repair between January 2009 and August 2017 was performed at our pediatric surgical units. Presenting symptoms, birth weight, radiological findings, associated anomalies, the type of surgery performed were analyzed. (1) 152 patients were identified, out of which 82 were males, and 70 were females; (2) the average birth weight of children with AP was less than that of healthy newborns...
June 16, 2018: Pediatric Surgery International
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