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https://www.readbyqxmd.com/read/29677556/prenatal-exposure-to-polychlorinated-biphenyls-and-fetal-growth-in-british-girls
#1
Jill F Patel, Terryl J Hartman, Andreas Sjodin, Kate Northstone, Ethel V Taylor
Polychlorinated biphenyls (PCBs) are synthetic chemicals that bioaccumulate in the food chain. PCBs were used primarily for industrial applications due to their insulating and fire retardant properties, but were banned in the 1970s in the United States and in the 1980s in the United Kingdom, as adverse health effects following exposure were identified. Previous studies of populations with high PCB exposure have reported inverse associations with birth weight and gestational length. Birth weight is a powerful predictor of infant survival, and low birth weight can predispose infants to chronic conditions in adult life such as diabetes and cardiovascular diseases...
April 17, 2018: Environment International
https://www.readbyqxmd.com/read/29676341/the-prevalence-and-risk-factors-for-trichomonas-vaginalis-infection-amongst-human-immunodeficiency-virus-infected-pregnant-women-attending-the-antenatal-clinics-of-a-university-teaching-hospital-in-lagos-south-western-nigeria
#2
Olaolopin Ijasan, Kehinde Sharafadeen Okunade, Ayodeji Ayotunde Oluwole
Background: Trichomonas vaginalis infection is the most prevalent non-viral sexually transmitted infection worldwide. Interactions between this infection and human immunodeficiency virus (HIV) may cause adverse pregnancy outcomes such as preterm labour, premature rupture of membranes, chorioamnionitis, low birth weight and post-abortal sepsis. Aims: This study was aimed to determine the prevalence and risk factors of T. vaginalis infection amongst HIV-positive pregnant women attending antenatal care at the Lagos University Teaching Hospital (LUTH), Lagos, Nigeria...
January 2018: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29672591/correction-catch-up-growth-in-the-first-two-years-of-life-in-extremely-low-birth-weight-elbw-infants-is-associated-with-lower-body-fat-in-young-adolescence
#3
Anke Raaijmakers, Lotte Jacobs, Maissa Rayyan, Theun Pieter van Tienoven, Els Ortibus, Elena Levtchenko, Jan A Staessen, Karel Allegaert
[This corrects the article DOI: 10.1371/journal.pone.0173349.].
2018: PloS One
https://www.readbyqxmd.com/read/29671167/vitamin-d-deficiency-and-depressive-symptoms-in-pregnancy-are-associated-with-adverse-perinatal-outcomes
#4
Eynav Elgavish Accortt, Amy Lamb, James Mirocha, Calvin J Hobel
Prenatal vitamin D deficiency and prenatal depression are both separately associated with adverse perinatal outcomes; however, to our knowledge no studies have investigated the effects of having both risk factors. Our objective was to determine to what extent vitamin D deficiency predicts adverse perinatal outcomes and whether elevated depressive symptoms in pregnancy places women at additional increased risk. This study was a secondary data analysis of prospective data collected from a cohort of pregnant women (N = 101) in an obstetric clinic of a large medical center...
April 18, 2018: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29670869/pathogenetic-and-prognostic-factors-for-neonatal-gastric-perforation-personal-experience-and-systematic-review-of-the-literature
#5
Chiara Iacusso, Alessandro Boscarelli, Fabio Fusaro, Pietro Bagolan, Francesco Morini
Introduction: Neonatal gastric perforation (NGP) is a rare entity. Our aim was to report our experience and review the recent literature to characterize NGP, describe associated factors, and define prognostic factors. Materials and methods: Retrospective review of all consecutive patients with NGP treated between June 2009 and December 2017 in a third level pediatric hospital. In addition, a systematic review of Medline and Scopus database was performed using a defined strategy...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29669381/prevalence-of-congenital-cmv-infection-and-antiviral-therapy-in-very-low-birth-weight-infants-observations-of-the-german-neonatal-network
#6
Alexander Humberg, Viola Leienbach, Mats I Fortmann, Tanja K Rausch, Horst Buxmann, Andreas Müller, Egbert Herting, Christoph Härtel, Wolfgang Göpel
BACKGROUND: To determine the prevalence of congenital CMV infection (cCMV) in very-low-birth-weight infants (VLBWI) and to evaluate epidemiological characteristics of VLBWI with antiviral therapy (AT). METHODS: CMV-specific PCR in umbilical cord tissue was performed (n=3330). Univariate analyses and logistic regression models were used to identify associations with outcome. RESULTS: 22/3330 VLBWI received AT (0.66%). 4 of these (0.12%) were PCR positive, with 2 VLBWI showing pathological screening for hearing loss...
April 18, 2018: Klinische Pädiatrie
https://www.readbyqxmd.com/read/29669077/genetic-parameters-for-reproductive-traits-at-different-parities-in-large-white-pigs
#7
Jian Ye, Cheng Tan, Xiaoxiang Hu, Aiguo Wang, Zhenfang Wu
Univariate or bivariate animal models were used to estimate the variance components and co-variance components for eight reproductive traits: total number born (TNB), number born alive (NBA), total litter weight of piglets born alive (BALWT), number of healthy births (NHB), number of weak births (NWB), number of deformed fetuses (NDF), number of stillborn (NSB), and number of mummified pigs (MUMM). In addition, the phenotypic and genetic correlations between traits at different parities were also estimated...
April 14, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29669005/fertility-and-neonatal-outcomes-of-embryos-achieving-blastulation-on-day-7-are-they-of-clinical-value
#8
Tong Du, Yun Wang, Yong Fan, Shiyi Zhang, Zhiguang Yan, Weina Yu, Qianwen Xi, Qiuju Chen, Ben W Mol, Qifeng Lyu, Yanping Kuang
STUDY QUESTION: Is transferring embryos that achieve blastulation on Day 7 effective and safe? SUMMARY ANSWER: Embryos that achieve blastulation on Day 7 resulted in clinically relevant rates of clinical pregnancy (32.5%) and live birth (25.2%), and newborns have a similar risk of low birth weight, congenital malformations or early neonatal death compared with those derived from Days 5 and 6 blastocysts. WHAT IS KNOWN ALREADY: Potential advantages of blastocyst transfer over cleavage embryo transfer have led to a shift toward the former in IVF practice...
April 13, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29668548/clinical-course-of-homozygous-hemoglobin-constant-spring-in-pediatric-patients
#9
Patcharee Komvilaisak, Arunee Jetsrisuparb, Goonnapa Fucharoen, Ratana Komwilaisak, Junya Jirapradittha, Pakaphan Kiatchoosakun
BACKGROUND: Hemoglobin (Hb) Constant Spring is an alpha-globin gene variant due to a mutation of the stop codon resulting in the elongation of the encoded polypeptide from 141 to 172 amino acid residues. Patients with homozygous Hb Constant Spring are usually mildly anemic. METHODS: We retrospectively describe clinical manifestations, diagnosis, laboratory investigations, treatment, and associated findings in pediatric patients with homozygous Hb Constant Spring followed-up at Srinagarind Hospital...
April 17, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29667718/trajectories-of-psychopathology-in-extremely-low-birth-weight-survivors-from-early-adolescence-to-adulthood-a-20-year-longitudinal-study
#10
Ryan J Van Lieshout, Mark A Ferro, Louis A Schmidt, Michael H Boyle, Saroj Saigal, Katherine M Morrison, Karen J Mathewson
BACKGROUND: Individuals born extremely preterm are exposed to significant perinatal stresses that are associated with an increased risk of psychopathology. However, a paucity of longitudinal studies has prevented the empirical examination of long-term, dynamic effects of perinatal adversity on mental health. Here, internalizing and externalizing problems from adolescence through adulthood were compared in individuals born at extremely low birth weight (ELBW; <1,000 g) and normal birth weight (NBW; >2,500 g)...
April 18, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29665758/the-efficacy-of-adjunct-tacrolimus-treatment-in-pregnancy-outcomes-in-patients-with-systemic-lupus-erythematosus
#11
K Ichinose, S Sato, Y Kitajima, Y Horai, K Fujikawa, M Umeda, S Fukui, A Nishino, T Koga, S Y Kawashiri, N Iwamoto, M Tamai, H Nakamura, T Origuchi, I Yasuhi, H Masuzaki, A Kawakami
Systemic lupus erythematosus (SLE) involves multiple organ systems and primarily affects women during their reproductive years. Pregnancy in a woman with SLE may lead to higher rates of disease flares. Little is known regarding which medications are safe to maintain remission and/or treat flares throughout such pregnancies. Here we retrospectively analyzed the efficacy of tacrolimus (TAC) in the pregnancy outcomes of SLE patients. We studied the 54 deliveries of 40 SLE patients over an eight-year period from 2008 to 2016...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29664656/maternal-anthropometric-characteristics-and-adverse-pregnancy-outcomes-in-iranian-women-a-confirmation-analysis
#12
Hayedeh Hoorsan, Hamid Alavi Majd, Shahla Chaichian, Abolfazl Mehdizadehkashi, Roza Hoorsan, Meisam Akhlaqghdoust, Yousef Moradi
BACKGROUND: Adverse pregnancy outcome are frequent in developing countries. Pregnancy outcomes are influenced by numerous factors. It seems that maternal anthropometric indices are among the most important factors in this era. The aim of this study was to determine any association between maternal anthropometric characteristics and adverse pregnancy outcomes in Iranian women and provide a predictive model by using factors affecting birth weight (BW) via the pathway analysis. METHODS: This study was performed in Alborz province between September 2014 and December 2016...
February 1, 2018: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29662925/factors-associated-with-improvements-in-mortality-and-morbidity-rates-of-very-low-birth-weight-infants-a-cohort-study
#13
Giancarlo Mari, Zoran Bursac, Patricia Jean Goedecke, Ramasubbareddy Dhanireddy
Objective . The objective of this study was to determine factors contributing to improvements in infant mortality rates (IMR) and composite morbidity-mortality in very-low-birth-weight (VLBW) infants after initiating a new perinatal program in 2009 at Regional One Health (ROH). VLBW infants account for 67% of infant deaths. Design . This is a pre-/postintervention cohort study of prospectively gathered data. Population . VLBW infants delivered at ROH during the 2004 to 2015 study period. Setting . ROH is a Regional Perinatal Center affiliated with the University of Tennessee Health Science Center...
2018: Global Pediatric Health
https://www.readbyqxmd.com/read/29662873/permissive-hypercapnia-results-in-decreased-functional-vessel-density-in-the-skin-of-extremely-low-birth-weight-infants
#14
Alexandra Francoise Puchwein-Schwepcke, Kristina Schottmayer, Zuzana Mormanová, Jens Dreyhaupt, Orsolya Genzel-Boroviczeny, Ulrich H Thome
Background: Ventilator-induced lung injury with subsequent bronchopulmonary dysplasia remains an important issue in the care of extremely low-birth-weight infants. Permissive hypercapnia has been proposed to reduce lung injury. Hypercapnia changes cerebral perfusion, but its influence on the peripheral microcirculation is unknown. Methods: Data were collected from 12 infants, who were randomized to a permissive high PCO2 target group (HTG) or a control group (CG)...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29662606/accouchement-g%C3%A3-mellaire-en-milieu-africain-une-analyse-de-10-ans-dans-le-district-de-bamako-au-mali-twin-deliveries-in-africa-10-years-analysis-in-bamako%C3%A2-s-district-in-mali
#15
Tiounkani Théra, Niani Mounkoro, Soumana Omar Traore, Albachar Hamidou, Mamadou Traore, Saleck Doumbia, Saoudatou Tall, Aminata Kouma
Introduction Aim: It was to determine the factors influencing the prognosis of the second twin's delivery. Methods: The study was retrospective and covered all cases of twin births registered at our maternity from 1st January 2007 to 31st December 2016 (10 years). Results: We recorded 34,899 deliveries among which 1374 twin deliveries (2.54%). Almost 15% were primiparous; 39.16% were referred; 69.10% and 15.5% without prenatal care. The factors negatively influencing prognosis for second twin were: a delay>15 minutes between twin deliveries, delayed caesarean section, non-qualification of the midwife, monochoreal, low birth weight...
2018: Pan African Medical Journal
https://www.readbyqxmd.com/read/29660440/the-long-term-effect-of-maternal-dietary-protein-restriction-on-5-ht-1a-receptor-function-and-behavioral-responses-to-stress-in-adulthood
#16
Wenrui Ye, Michael Duffy Pitlock, Martin A Javors, Brent Thompson, James D Lechleiter, Julie G Hensler
Maternal nutrition impacts fetal development, and may play a role in determining resilience to stress and vulnerability to stress-precipitated psychiatric disorders, such as anxiety and depression. In this study, we examined the effect of a reduction in maternal dietary protein during pregnancy on the brain neurochemistry and behavior of offspring. We focused specifically on the serotonin system, the 5-HT1A receptor and the responsivity of offspring as adults to stress. Dams were fed either a low protein diet (10% protein by weight) or isocaloric control diet (20% protein by weight)...
April 13, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29660063/five-successful-pregnancies-with-antenatal-anakinra-exposure
#17
Chelsey J F Smith, Christina D Chambers
Objectives: Our aim is to add to the limited existing prospective data on IL-1 inhibitor use in pregnancy. Methods: Data were obtained from the Organization of Teratology Information Specialists Autoimmune Disease in Pregnancy Project, a prospective cohort study of pregnancy outcomes in the USA and Canada. Eligible women were enrolled prior to 19 weeks' gestation between 2004 and 2017. Outcomes were obtained by maternal interview and medical record abstraction. Results: Five pregnancies with anakinra exposure were identified, all resulting in full-term singleton live births with no major or long-term complications...
April 12, 2018: Rheumatology
https://www.readbyqxmd.com/read/29659737/feeding-related-gut-microbial-composition-associates-with-peripheral-t-cell-activation-and-mucosal-gene-expression-in-african-infants
#18
Lianna F Wood, Bryan P Brown, Katie Lennard, Ulas Karaoz, Enock Havyarimana, Jo-Ann S Passmore, Anneke C Hesseling, Paul T Edlefsen, Louise Kuhn, Nicola Mulder, Eoin L Brodie, Donald L Sodora, Heather B Jaspan
Background: Exclusive breastfeeding reduces the rate of postnatal HIV transmission compared to non-exclusive breastfeeding, however the mechanisms of this protection are unknown. Our study was designed to interrogate the mechanisms underlying the protective effect of exclusive breastfeeding (EBF). Methods: A prospective, longitudinal study of infants from a high HIV prevalence, low-income setting in South Africa. We evaluated the role of any non-breastmilk feeds excluding prescribed medicines...
April 5, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29659372/consequences-of-antepartum-depression
#19
Jonathan Schaffir
To counsel women about risks and benefits of depression treatment during pregnancy, clinicians must appreciate the potential consequences of untreated depression on the mother and her unborn child. Many studies have demonstrated associations between untreated depression during pregnancy and a range of adverse outcomes, including low birth weight, preterm delivery, preeclampsia, emergent operative delivery, postpartum depression, and both cognitive and behavioral deficits in the child. Although most of these associations are marked by low odds ratios and a host of potential confounding issues, they collectively provide considerable rationale for identifying depression in pregnancy and offering treatment for mothers at risk...
April 13, 2018: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29658624/review-of-the-nutrition-situation-in-the-eastern-mediterranean-region
#20
REVIEW
Lara Nasreddine, Jennifer J Ayoub, Ayoub Al Jawaldeh
This situation analysis for the World Health Organization Eastern Mediterranean Region focuses on specific nutrition indicators, namely low birth weight, exclusive breastfeeding, under- and overnutrition (anthropometric indicators) and anaemia. The regional average prevalence of low birth weight and exclusive breastfeeding was estimated at 19.31% and 29.3%, respectively. Stunting, wasting and underweight had an average prevalence of 28%, 8.69% and 18%, respectively. Afghanistan, Djibouti, Pakistan, Sudan and Yemen had the highest burden of stunting (> 30%)...
April 5, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
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