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hepatic insuficiency

Camila O de Souza, Gretchen K Vannice, José C Rosa Neto, Philip C Calder
Although dietary fatty acids can modulate metabolic and immune responses, the effects of palmitoleic acid (16:1n-7) remain unclear. Since this monounsaturated fatty acid is described as a lipokine, studies with cell culture and rodent models have suggested it enhances whole body insulin sensitivity, stimulates insulin secretion by β cells, increases hepatic fatty acid oxidation, improves the blood lipid profile, and alters macrophage differentiation. However, human studies report elevated blood levels of palmitoleic acid in people with obesity and metabolic syndrome...
January 2018: Molecular Nutrition & Food Research
Terri Y Lim, Robert L Poole, Natalie M Pageler
Propylene glycol (PG) is a commonly used solvent for oral, intravenous, and topical pharmaceutical agents. Although PG is generally considered safe, when used in high doses or for prolonged periods, PG toxicity can occur. Reported adverse effects from PG include central nervous system (CNS) toxicity, hyperosmolarity, hemolysis, cardiac arrhythmia, seizures, agitation, and lactic acidosis. Patients at risk for toxicity include infants, those with renal or hepatic insuficiency, epilepsy, and burn patients receiving extensive dermal applications of PG containing products...
October 2014: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
T Frangov, V Dimitrova
UNLABELLED: Cholangiocellular carcinoma is the second on rate primary liver cancer (7-10%), after hepatocellular carcinoma--(80-85%). The aim of this study is to present some diferrencies in clinical and pathological features in comparison to other liver tumors. MATERIALS AND METHODS: In the period 1991-2002 years, 105 patients with primary liver cancer were operated; 9 of them (8.5%) had cholangiocellular carcinoma (CCC). The men were 5, the women--4, and the mean age 51 years...
2004: Khirurgiia
R Díaz Garduño, V M Arrubarrena
In our Service of Gastroenterology (Hospital Colonia) there were 16 patients in whom surgical plastic repair of the biliary tract was done. Out of these, the files of 11 were reviewed; national and international related medical literature is reviewed. In all cases the lesion was related to previous surgery. The main symptoms were: jaundice, acolia, coluria and pain. Laboratory tests were of help in preoperelative diagnosis and postoperative follow up. Operative findings were section and or ligature of the hepatic duct or the common bile duct...
July 1979: Revista de Gastroenterología de México
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