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nutrition metabolism and cardiovascular disease

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https://www.readbyqxmd.com/read/29783969/association-between-thyroid-hormones-and-the-components-of-metabolic-syndrome
#1
Jieun Jang, Youngsook Kim, Jaeyong Shin, Sang Ah Lee, Young Choi, Eun-Cheol Park
BACKGROUND: Thyroid hormones are known to have direct and indirect effects on metabolism. Individuals with metabolic syndrome, a disease that is growing in incidence at a rapid rate, are at higher risk for cardiovascular disease, diabetes, and cancer. The aim of this study was to identify whether significant correlations exist between thyroid hormone levels and components of the metabolic syndrome in the general population of Korea. METHODS: The data were collected from the sixth Korea National Health and Nutrition Examination Surveys from 2013 to 2015...
May 21, 2018: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/29783781/nutraceuticals-in-periodontal-health-a-systematic-review-on-the-role-of-vitamins-in-periodontal-health-maintenance
#2
REVIEW
Alfonso Varela-López, María D Navarro-Hortal, Francesca Giampieri, Pedro Bullón, Maurizio Battino, José L Quiles
Periodontal disease, a relevant public health problem worldwide, is generally considered a common pathology of elderly people. In this respect, there is agreement about that nutritional status may be a modifying factor in the progression and healing of the periodontal tissues. Vitamins have been recommended as nutraceuticals for prevention and treatment of some pathological conditions, such as cardiovascular diseases, obesity or cancer. Thus, a systematic approach to determining how the different vitamin type could ameliorate periodontal risks or improve periodontal health is necessary to further the understanding of the potential benefits and risks of vitamins supplementation use...
May 20, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29782204/paraoxonase-1-q192r-genotype-and-activity-affect-homocysteine-thiolactone-levels-in-humans
#3
Joanna Perła-Kaján, Kamila Borowczyk, Rafał Głowacki, Ottar Nygård, Hieronim Jakubowski
Genetic or nutritional deficiencies in 1 carbon and homocysteine (Hcy) metabolism elevate Hcy-thiolactone levels and are associated with cardiovascular and neurologic diseases. Hcy-thiolactone causes protein damage, cellular toxicity, and proatherogenic changes in gene expression in human cells and tissues. A polymorphic cardio-protective enzyme, paraoxonase 1 (PON1), hydrolyzes Hcy-thiolactone in vitro. However, whether Hcy-thiolactone hydrolysis is a physiologic function of the PON1 protein and whether polymorphisms in the PON1 gene affect Hcy-thiolactone levels in humans was unknown...
May 21, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29781483/dose-dependent-effects-of-fish-oil-on-cardio-metabolic-biomarkers-in-healthy-middle-aged-and-elderly-chinese-people-a-double-blind-randomized-controlled-trial
#4
Jia Song, Manjiang Hu, Cheng Li, Bo Yang, Qing Ding, Chunhong Wang, Limei Mao
n-3PUFA consumption has been widely accepted as a nutritional strategy for the secondary prevention of cardiovascular events in patients at high risk of cardiovascular disease (CVD), but little is known about the dose-response relationship between dietary n-3PUFA and serum biomarkers associated with cardiovascular health in the general population. The present study involved a 12-week double-blind, randomized controlled trial to explore the effects of fish oil with different doses (0.31, 0.62 and 1.24 g d-1 of EPA and DHA) on serum fatty acids and cardio-metabolic biomarkers including adiponectin, inflammatory markers, lipid profiles and fasting glucose in healthy middle-aged and elderly Chinese people...
May 21, 2018: Food & Function
https://www.readbyqxmd.com/read/29773464/sex-and-gender-differences-in-developmental-programming-of-metabolism
#5
REVIEW
Laura Dearden, Sebastien G Bouret, Susan E Ozanne
BACKGROUND: The early life environment experienced by an individual in utero and during the neonatal period is a major factor in shaping later life disease risk-including susceptibility to develop obesity, diabetes, and cardiovascular disease. The incidence of metabolic disease is different between males and females. How the early life environment may underlie these sex differences is an area of active investigation. SCOPE OF REVIEW: The purpose of this review is to summarize our current understanding of how the early life environment influences metabolic disease risk in a sex specific manner...
April 30, 2018: Molecular Metabolism
https://www.readbyqxmd.com/read/29768640/lipoprotein-profile-modifications-during-gestation-a-current-approach-to-cardiovascular-risk-surrogate-markers-and-maternal-fetal-unit-complications
#6
Ana Paula Caires Dos Santos, Ricardo David Couto
Several changes occur in lipid metabolism during gestation due to hormonal and metabolic changes, which are essential to satisfy the nutritional demands of the maternal-fetal unit development. The gestation shows two distinct periods that begin with fat accumulation, mainly in maternal adipose tissue, and the late phase, characterized by accelerated catabolism, with the increase of fatty acids in the circulation that causes hyperlipidemia, especially the one characterized as hypertriglyceridemia. Maternal hyperlipidemia may be associated with the development of maternal-fetal complications (preterm birth, preeclampsia, vascular complications) and the development of long-term cardiovascular disease...
May 16, 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29754804/diabetes-mellitus-and-cardiovascular-risk-update-of-the-recommendations-of-the-diabetes-and-cardiovascular-disease-working-group-of-the-spanish-diabetes-society-sed-2018
#7
Francisco Arrieta, Pedro Iglesias, Juan Pedro-Botet, Antonio Becerra, Emilio Ortega, Juan Carlos Obaya, Andreu Nubiola, Gonzalo Fernando Maldonado, Maria Del Mar Campos, Romina Petrecca, José Luis Pardo, Víctor Sánchez-Margalet, José Juan Alemán, Jorge Navarro, Santiago Duran, Francisco Javier Tébar, Manuel Aguilar, Fernando Escobar
This document is an update to the clinical practice recommendations for the management of cardiovascular risk factors in diabetes mellitus. The consensus is made by members of the Cardiovascular Risk Group of the Spanish Diabetes Society. We have proposed and updated interventions on lifestyle, pharmacological treatment indicated to achieve therapeutic objectives according to the levels of HbA1c, degree of obesity, hypertension, hyperlipidemia, heart failure, platelet antiagregation, renal insufficiency, and diabetes in the elderly, as well as new biomarkers of interest in the evaluation of cardiovascular risk in individuals with diabetes mellitus...
May 10, 2018: Clínica e Investigación en Arteriosclerosis
https://www.readbyqxmd.com/read/29752697/biofortification-of-safflower-an-oil-seed-crop-engineered-for-ala-targeting-better-sustainability-and-plant-based-omega-3-fatty-acids
#8
Arti Rani, Asha Panwar, Manjary Sathe, Karunakara Alageri Chandrashekhara, Anil Kush
Alpha-linolenic acid (ALA) deficiency and a skewed n6:n3 fatty acid ratio in the diet is a major explanation for the prevalence of cardiovascular diseases and inflammatory/autoimmune diseases. There is mounting evidence of the health benefits associated with omega-3 long chain polyunsaturated fatty acids (LC PUFA's). Although present in abundance in fish, a number of factors limit our consumption of fish based omega-3 PUFA's. To name a few, overexploitation of wild fish stocks has reduced their sustainability due to increased demand of aquaculture for fish oil and meal; the pollution of marine food webs has raised concerns over the ingestion of toxic substances such as heavy metals and dioxins; vegetarians do not consider fish-based sources for supplemental nutrition...
May 11, 2018: Transgenic Research
https://www.readbyqxmd.com/read/29750655/metabolic-risk-factors-in-adolescent-girls-with-type-1-diabetes
#9
Cíntia Castro-Correia, Rita Santos-Silva, Marta Pinheiro, Carla Costa, Manuel Fontoura
BACKGROUND: The incidence of pediatric metabolic syndrome (MS) has progressively increased. The incidence of type 1 diabetes mellitus (T1DM) has also increased. Thus, some children and adolescents with T1DM exhibit MS parameters. The aim of the study was to evaluate the presence of MS parameters in female adolescents with T1DM based on their nutritional status. METHODS: We evaluated 44 adolescents with T1DM (consecutive non-randomized sample) aged between 14 and 18 years, who were on intensive therapy with insulin...
May 11, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29748656/the-capacity-load-model-of-non-communicable-disease-risk-understanding-the-effects-of-child-malnutrition-ethnicity-and-the-social-determinants-of-health
#10
REVIEW
Jonathan C K Wells
The capacity-load model is a conceptual model developed to improve understanding of the life-course aetiology of non-communicable diseases (NCDs) and their ecological and societal risk factors. The model addresses continuous associations of both (a) nutrition and growth patterns in early life and (b) lifestyle factors at older ages with NCD risk. Metabolic capacity refers to physiological traits strongly contingent on early nutrition and growth during the first 1000 days, which promote the long-term capacity for homeostasis in the context of fuel metabolism and cardiovascular health...
May 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29745362/does-dietary-nitrate-say-no-to-cardiovascular-ageing-current-evidence-and-implications-for-research
#11
Mario Siervo, Filippo Scialò, Oliver M Shannon, Blossom C M Stephan, Ammar W Ashor
CVD are characterised by a multi-factorial pathogenesis. Key pathogenetic steps in the development of CVD are the occurrence of endothelial dysfunction and formation of atherosclerotic lesions. Reduced nitric oxide (NO) bioavailability is a primary event in the initiation of the atherosclerotic cascade. NO is a free radical with multiple physiological functions including the regulation of vascular resistance, coagulation, immunity and oxidative metabolism. The synthesis of NO proceeds via two distinct pathways identified as enzymatic and non-enzymatic...
May 2018: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/29731703/metabolic-syndrome-and-neuroprotection
#12
REVIEW
Melisa Etchegoyen, Mariana H Nobile, Francisco Baez, Barbara Posesorski, Julian González, Néstor Lago, José Milei, Matilde Otero-Losada
Introduction: Over the years the prevalence of metabolic syndrome (MetS) has drastically increased in developing countries as a major byproduct of industrialization. Many factors, such as the consumption of high-calorie diets and a sedentary lifestyle, bolster the spread of this disorder. Undoubtedly, the massive and still increasing incidence of MetS places this epidemic as an important public health issue. Hereon we revisit another outlook of MetS beyond its classical association with cardiovascular disease (CVD) and Diabetes Mellitus Type 2 (DM2), for MetS also poses a risk factor for the nervous tissue and threatens neuronal function...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29727376/cardiovascular-disease-risk-among-older-immigrants-in-the-united-states-a-comparison-of-risk-measures
#13
Tina R Sadarangani, Deborah Chyun, Chau Trinh-Shevrin, Gary Yu, Christine Kovner
BACKGROUND: In the United States, 16 million immigrants are 50 years and older, but little is known about their cardiometabolic health and how to best assess their cardiovascular disease (CVD) risk. Aging immigrants may therefore not be benefitting from advances in CVD prevention. OBJECTIVE: In this study, we estimate and compare CVD risk in a nationally representative sample of aging immigrants using 3 different measures. METHODS: This was a cross-sectional analysis using National Health and Nutrition Examination Survey data...
April 27, 2018: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29723102/cardioprotection-by-cocoa-polyphenols-and-%C3%AF-3-fatty-acids-a-disease-prevention-perspective-on-aging-associated-cardiovascular-risk
#14
Sergio Davinelli, Graziamaria Corbi, Stefano Righetti, Barry Sears, Hector Hugo Olarte, Davide Grassi, Giovanni Scapagnini
Cardiovascular disease (CVD) remains the leading cause of death today. Many of the biochemical alterations associated with the pathophysiology of CVD can be modified by adequate intakes of bioactive nutrients through a correct diet or supplementation. Recently, there has been growing public and clinical interest in cocoa polyphenols (CPs) and omega-3 (ω-3) fatty acids. A plethora of nutritional intervention trials and experimental studies demonstrates that consumption of these bioactive food compounds is beneficial to promote cardiovascular health...
May 3, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29718839/evaluation-of-the-physical-activity-level-nutrition-quality-and-depression-in-patients-with-metabolic-syndrome-comparative-study
#15
İsmet Kazaz, Ender Angin, Seray Kabaran, Gözde İyigün, Berkiye Kirmizigil, Mehtap Malkoç
Metabolic syndrome (MetS) is a complex problem that contains risk factors related with obesity, cardiovascular diseases, and type-II diabetes. The incidence of MetS is increasing every year throughout the world.The aim of this study was to evaluate and compare physical activity levels, nutrition quality, and depression status of the individuals who are diagnosed with and without MetS.International Physical Activity Questionnaire (IPAQ), Mediterranean Diet Adherence Screener (MEDAS), Beck Depression Inventory (BDI) was used...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29712560/cardiovascular-disease-risk-factor-responses-to-a-type-2-diabetes-care-model-including-nutritional-ketosis-induced-by-sustained-carbohydrate-restriction-at-1-year-an-open-label-non-randomized-controlled-study
#16
Nasir H Bhanpuri, Sarah J Hallberg, Paul T Williams, Amy L McKenzie, Kevin D Ballard, Wayne W Campbell, James P McCarter, Stephen D Phinney, Jeff S Volek
BACKGROUND: Cardiovascular disease (CVD) is a leading cause of death among adults with type 2 diabetes mellitus (T2D). We recently reported that glycemic control in patients with T2D can be significantly improved through a continuous care intervention (CCI) including nutritional ketosis. The purpose of this study was to examine CVD risk factors in this cohort. METHODS: We investigated CVD risk factors in patients with T2D who participated in a 1 year open label, non-randomized, controlled study...
May 1, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29696574/optimising-the-bariatric-patients-outcome-through-cardiac-rehabilitation-approach
#17
Nor Hanim Mohamad Hanapi, Brenda Saria Yuliawiratman, Lee Lee Lai, Hazwani Halil, J G Koo, Anwar Suhaimi
Bariatric surgery offers a therapeutic alternative with favourable weight management, cardiovascular, metabolic and functional outcomes. Bariatric individuals often have functional impairments pre-operatively that can be addressed to improve post-operative results and eventual functional independence. Multidisciplinary team offers the best approach to address peri-operative needs and sustainable weight loss thereafter. We exemplified the application of cardiac rehabilitation therapeutic model in managing two bariatric clients with specific bariatric-related challenges...
April 26, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29693637/paltem-what-parameters-should-be-collected-in-disaster-settings-to-assess-the-long-term-outcomes-of-famine
#18
REVIEW
Alexandra Moraru, Maria Moitinho de Almeida, Jean-Marie Degryse
Evidence suggests that nutritional status during fetal development and early life leaves an imprint on the genome, which leads to health outcomes not only on a person as an adult but also on his offspring. The purpose of this study is to bring forth an overview of the relevant parameters that need to be collected to assess the long-term and transgenerational health outcomes of famine. A literature search was conducted for the most pertinent articles on the epigenetic effects of famine. The results were compiled, synthesized and discussed with an expert in genetics for critical input and validation...
April 25, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29677105/the-chemical-composition-and-metabolic-effects-of-attalea-phalerata-nut-oil-in-hyperlipidemic-rats-induced-by-a-high-fructose-diet
#19
Débora da Silva Baldivia, Eliana Janet Sanjinez-Argandonã, Kátia Ávila Antunes, Izabel Cristina Freitas Moraes, Edson Lucas Dos Santos, Kely de Picoli Souza
The fatty acids found in nuts are important regulators of the metabolism. These acids are frequently associated with a reduction of serum cholesterol and body fat and a lower risk of developing cardiovascular disease. In this context, the aim of this study was to identify and quantify the nut oil fatty acids from Attalea phalerata and investigate their metabolic effects in rats with hyperlipidemia induced by a diet rich in fructose. Oleic and lauric acids were the major compounds found in the A. phalerata nut oil (APNO)...
April 20, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29668714/socioeconomic-inequalities-in-the-prevalence-of-biomarkers-of-cardio-metabolic-disease-in-south-korea-comparison-of-the-health-examinees-study-to-a-nationally-representative-survey
#20
Sujin Kim, Juhwan Oh, Jongho Heo, Hwa-Young Lee, Jong-Koo Lee, S V Subramanian, Daehee Kang
BACKGROUND/OBJECTIVES: This study aimed to examine socioeconomic inequalities in the prevalence of biomarkers of cardiovascular disease and diabetes in the newly developed large-scale genomic cohort study of Korean adults, the Health Examinees-Gem (HEXA-G), with a comparison of the nationally representative cross-sectional study, the Korea National Health and Nutrition Examination Survey (K-NHANES). SUBJECTS/METHODS: Using the HEXA-G and the K-NHANES from 2007-2012, we analyzed the age-adjusted relative risk (RR) and prevalence of enlarged waist circumference (EWC), elevated triglycerides (ET), low HDL cholesterol (LHC), elevated blood pressure (EBP) and elevated blood glucose (EBG) by income and educational groups for adults at age 40-69...
2018: PloS One
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