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nutrition metabolism and cardiovascular disease

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https://www.readbyqxmd.com/read/28813611/intrauterine-growth-restricted-yucatan-miniature-pigs-experience-early-catch-up-growth-leading-to-greater-adiposity-and-impaired-lipid-metabolism-as-young-adults
#1
Semone B Myrie, Leslie L McKnight, J Christopher King, John J McGuire, Bruce N Van Vliet, Sukhinder K Cheema, Robert F Bertolo
Early nutrition has critical influences on cardiovascular disease risk in adulthood. The study objectives were to evaluate the impact of low birth weight on fasting and postprandial lipid metabolism and endothelium function in Yucatan miniature pigs. Intrauterine growth-restricted (IUGR) piglets (n = 6, 3 d old, 0.73 ± 0.04 kg) were paired with normal weight (NW) same-sex littermates (n = 6, 1.11 ± 0.05 kg) and fed milk replacer ad libitum for 4 wk. Thereafter, all pigs were fed a standard diet ad libitum for 5 h/d with growth, intakes and blood samples collected for 8 mo...
August 16, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28796289/medicine-is-not-health-care-food-is-health-care-plant-metabolic-engineering-diet-and-human-health
#2
REVIEW
Cathie Martin, Jie Li
Contents I. II. III. IV. V. VI. References SUMMARY: Plants make substantial contributions to our health through our diets, providing macronutrients for energy and growth as well as essential vitamins and phytonutrients that protect us from chronic diseases. Imbalances in our food can lead to deficiency diseases or obesity and associated metabolic disorders, increased risk of cardiovascular diseases and cancer. Nutritional security is now a global challenge which can be addressed, at least in part, through plant metabolic engineering for nutritional improvement of foods that are accessible to and eaten by many...
August 10, 2017: New Phytologist
https://www.readbyqxmd.com/read/28792455/cardio-metabolic-benefits-of-plant-based-diets
#3
REVIEW
Hana Kahleova, Susan Levin, Neal Barnard
Cardio-metabolic disease, namely ischemic heart disease, stroke, obesity, and type 2 diabetes, represent substantial health and economic burdens. Almost one half of cardio-metabolic deaths in the U.S. might be prevented through proper nutrition. Plant-based (vegetarian and vegan) diets are an effective strategy for improving nutrient intake. At the same time, they are associated with decreased all-cause mortality and decreased risk of obesity, type 2 diabetes, and coronary heart disease. Evidence suggests that plant-based diets may reduce the risk of coronary heart disease events by an estimated 40% and the risk of cerebral vascular disease events by 29%...
August 9, 2017: Nutrients
https://www.readbyqxmd.com/read/28783113/-omics-in-human-colostrum-and-mature-milk-looking-to-old-data-with-new-eyes
#4
REVIEW
Flaminia Bardanzellu, Vassilios Fanos, Alessandra Reali
Human Milk (HM) is the best source for newborn nutrition until at least six months; it exerts anti-inflammatory and anti-infective functions, promotes immune system formation and supports organ development. Breastfeeding could also protect from obesity, diabetes and cardiovascular disease. Furthermore, human colostrum (HC) presents a peculiar role in newborn support as a protective effect against allergic and chronic diseases, in addition to long-term metabolic benefits. In this review, we discuss the recent literature regarding "omics" technologies and growth factors (GF) in HC and the effects of pasteurization on its composition...
August 7, 2017: Nutrients
https://www.readbyqxmd.com/read/28770334/association-between-organic-food-consumption-and-metabolic-syndrome-cross-sectional-results-from-the-nutrinet-sant%C3%A3-study
#5
Julia Baudry, Hélène Lelong, Solia Adriouch, Chantal Julia, Benjamin Allès, Serge Hercberg, Mathilde Touvier, Denis Lairon, Pilar Galan, Emmanuelle Kesse-Guyot
PURPOSE: Metabolic syndrome (MetS), a multicomponent condition, is a cardiovascular disease predictor. Although exposure to agricultural pesticides has been suggested as a potential contributor to the rising rates of obesity, type 2 diabetes, and other features of metabolic disorders, no studies have focused on the association between consumption of organic food (produced without synthetic pesticides) and MetS. We aimed to investigate the cross-sectional association between organic food consumption and MetS in French adults to determine whether it would be worth conducting further studies, particularly large prospective and randomised trials...
August 2, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28758978/dietary-approaches-in-the-management-of-diabetic-patients-with-kidney-disease
#6
REVIEW
Gang Jee Ko, Kamyar Kalantar-Zadeh, Jordi Goldstein-Fuchs, Connie M Rhee
Chronic kidney disease (CKD) is one of the most prevalent complications of diabetes, and patients with diabetic kidney disease (DKD) have a substantially higher risk of cardiovascular disease and death compared to their non-diabetic CKD counterparts. In addition to pharmacologic management strategies, nutritional and dietary interventions in DKD are an essential aspect of management with the potential for ameliorating kidney function decline and preventing the development of other end-organ complications. Among DKD patients with non-dialysis dependent CKD, expert panels recommend lower dietary protein intake of 0...
July 31, 2017: Nutrients
https://www.readbyqxmd.com/read/28739653/the-metabolic-syndrome-in-children-and-adolescents-shifting-the-focus-to-cardiometabolic-risk-factor-clustering
#7
Sheela N Magge, Elizabeth Goodman, Sarah C Armstrong
Metabolic syndrome (MetS) was developed by the National Cholesterol Education Program Adult Treatment Panel III, identifying adults with at least 3 of 5 cardiometabolic risk factors (hyperglycemia, increased central adiposity, elevated triglycerides, decreased high-density lipoprotein cholesterol, and elevated blood pressure) who are at increased risk of diabetes and cardiovascular disease. The constellation of MetS component risk factors has a shared pathophysiology and many common treatment approaches grounded in lifestyle modification...
July 24, 2017: Pediatrics
https://www.readbyqxmd.com/read/28731561/association-of-glycaemic-index-and-glycaemic-load-with-metabolic-syndrome-in-an-iranian-adult-population-isfahan-healthy-heart-program
#8
Noushin Mohammadifard, Marjan Mansourian, Firouzeh Sajjadi, Maryam Maghroun, Ali Pourmoghaddas, Narges Yazdekhasti, Nizal Sarrafzadegan
AIM: There is controversy around the clinical effects of the dietary glycaemic index (GI) and glycaemic load (GL) on cardiovascular diseases risk factors such as metabolic syndrome (MetS). So, the present study was performed to evaluate the relationship between GI or GL and metabolic syndrome in an Iranian adult population in 2007. METHODS: The study was based on data from a sub-sample of the Isfahan Healthy Heart Program (IHHP), collected across three cities in central Iran, in the year 2007...
February 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28725542/self-reported-health-and-behavioral-factors-are-associated-with-metabolic-syndrome-in-americans-aged-40-and-over
#9
Ying Liu, Ifeoma D Ozodiegwu, Jeffrey C Nickel, Kesheng Wang, Laura R Iwasaki
To determine whether behavioral factors differ among metabolic conditions and self-reported health, and to determine whether self-reported health is a valid predictor of metabolic syndrome (MetS). A total of 2997 individuals (≥ 40 years old) were selected from four biennial U.S. National Health and Nutrition Examination Surveys (2007-2014). A set of weighted logistic regression models were used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs)Individuals with light physical activity are more likely to have MetS and report poor health than those with vigorous physical activity with OR = 3...
September 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28715994/fgf23-and-nutritional-metabolism
#10
Lindsay R Pool, Myles Wolf
The discovery of fibroblast growth factor 23 (FGF23) has provided a more complete understanding of the regulation of phosphate and mineral homeostasis in health and in chronic kidney disease. It has also offered new insights into stratification of risk of cardiovascular events and death among patients with chronic kidney disease and the general population. In this review, we provide an overview of FGF23 biology and physiology, summarize clinical outcomes that have been associated with FGF23, discuss potential mechanisms for these observations and their public health implications, and explore clinical and population health interventions that aim to reduce FGF23 levels and improve public health...
July 17, 2017: Annual Review of Nutrition
https://www.readbyqxmd.com/read/28715991/trimethylamine-n-oxide-the-microbiome-and-heart-and-kidney-disease
#11
Steven H Zeisel, Manya Warrier
Trimethylamine N-oxide (TMAO) is a biologically active molecule and is a putative promoter of chronic diseases including atherosclerosis in humans. Host intestinal bacteria produce its precursor trimethylamine (TMA) from carnitine, choline, or choline-containing compounds. Most of the TMA produced is passively absorbed into portal circulation, and hepatic flavin-dependent monooxygenases (FMOs) efficiently oxidize TMA to TMAO. Both observational and experimental studies suggest a strong positive correlation between increased plasma TMAO concentrations and adverse cardiovascular events, such as myocardial infarction, stroke, and death...
July 17, 2017: Annual Review of Nutrition
https://www.readbyqxmd.com/read/28689854/impact-of-cardiac-rehabilitation-and-exercise-training-programs-in-coronary-heart-disease
#12
REVIEW
Sergey Kachur, Vasutakarn Chongthammakun, Carl J Lavie, Alban De Schutter, Ross Arena, Richard V Milani, Barry A Franklin
Cardiovascular rehabilitation (CR) is the process of developing and maintaining an optimal level of physical, social, and psychological well-being in order to promote recovery from cardiovascular (CV) illness. It is a multi-disciplinary approach encompassing supervised exercise training, patient counseling, education and nutritional guidance that may also enhance quality of life. Beneficial CV effects may include improving coronary heart disease risk factors; particularly exercise capacity, reversing cardiac remodeling, and favorably modifying metabolism and systemic oxygen transport...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28686726/examining-the-gender-difference-in-the-association-between-metabolic-syndrome-and-the-mean-leukocyte-telomere-length
#13
Yuan-Yuei Cheng, Tung-Wei Kao, Yaw-Wen Chang, Chen-Jung Wu, Tao-Chun Peng, Li-Wei Wu, Hui-Fang Yang, Fang-Yih Liaw, Wei-Liang Chen
The mechanism of cellular aging likely involves decreased telomere length and is associated with age-related diseases such as cardiovascular disease. Metabolic syndrome (MetS) is an important risk factor for CVD. The purpose of this study was to investigate the association between LTL and MetS. We evaluated 7370 participants in the National Health and Nutrition Examination Survey (1999-2002). The association between LTL and individual MetS components and the number of MetS components was analyzed by multivariable regression models, adjusting for gender, race/ethnicity, albumin, C-reactive protein, alanine transaminase, uric acid and medical condition...
2017: PloS One
https://www.readbyqxmd.com/read/28685012/lycium-barbarum-reduces-abdominal-fat-and-improves-lipid-profile-and-antioxidant-status-in-patients-with-metabolic-syndrome
#14
Mayara Zagonel de Souza Zanchet, Geisson Marcos Nardi, Letícia de Oliveira Souza Bratti, Fabíola Branco Filippin-Monteiro, Claudriana Locatelli
Natural antioxidants present in fruits have attracted considerable interest due to their presumed safety and potential nutritional value. Even though antioxidant activities of many fruits have been reported, the effects of phytochemicals of goji berry (GB) in patients with metabolic syndrome have not been investigated. In this study, we examined anthropometric and biochemical parameters in patients with metabolic syndrome after the consumption of GB. The patients were divided into two groups, control (C) and supplemented (S), and followed up for 45 days...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28679380/a-novel-botanical-formula-prevents-diabetes-by-improving-insulin-resistance
#15
Juntao Kan, Rodney A Velliquette, Kerry Grann, Charlie R Burns, Jeff Scholten, Feng Tian, Qi Zhang, Min Gui
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a major risk factor for cardiovascular disease, and the prevalence has increased significantly in recent decades to epidemic proportions in China. Individually, fenugreek (Trigonella foenum graecum) seed, mulberry (Morus alba L.) leaf and American ginseng (Panax quinquefolius) root can improve glycemia in various animal models and humans with impaired glucose metabolism and T2DM. The aim of this study was to design an optimized botanical formula containing these herbal extracts as a nutritional strategy for the prevention of insulin resistance and T2DM...
July 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28678523/nutritional-biomarkers-current-view-and-future-perspectives
#16
Shubhra Pande, Valentina A Kratasyuk, Nadezhda N Medvedeva, Oxana A Kolenchukova, Alla B Salmina
There is a poor relationship between nutrient intake and existing nutritional biomarkers due to variety of factors affecting their sensitivity and specificity. To explore the impact of nutrients at molecular level and devising a sensitive biomarker, proteomics is a central technology with sirtuins as one of the most promising nutritional biomarker. Sirtuins (seven mammalian sirtuins reported so far), have been reported to perform protein deacetylases and ADP-ribosyltransferases activity. It is distributed in different cellular compartments thereby controlling several metabolic processes...
July 5, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28678155/influence-of-the-periodontal-disease-the-most-prevalent-inflammatory-event-in-peroxisome-proliferator-activated-receptors-linking-nutrition-and-energy-metabolism
#17
REVIEW
Lourdes Román-Malo, Pedro Bullon
Periodontal disease is considered one of the main pathologic diseases occurring in humans. Its pathologic process involves inflammatory reactions producing periodontal bone resorption and the tooth loss. But some patients do not present an evident clinical inflammation with bone resorption, and in others, the inflammation is prominent without bone resorption. A key question could be to investigate a different way of responding to aggression. Inflammation requires a complex intracellular metabolic process, starting with the harmful recognition and activation of the inflammasome, continues the energy supply with the alteration of oxidative stress conditions, and finishes with the elimination of the aggression with autophagy/apoptosis mechanisms, then concludes with recovery...
July 5, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28669628/role-of-oxidative-stress-in-cardiovascular-disease-outcomes-following-exposure-to-ambient-air-pollution
#18
REVIEW
Frank J Kelly, Julia C Fussell
Exposure to ambient air pollution is associated with adverse cardiovascular outcomes. These are manifested through several, likely overlapping, pathways including at the functional level, endothelial dysfunction, atherosclerosis, pro-coagulation and alterations in autonomic nervous system balance and blood pressure. At numerous points within each of these pathways, there is potential for cellular oxidative imbalances to occur. The current review examines epidemiological, occupational and controlled exposure studies and research employing healthy and diseased animal models, isolated organs and cell cultures in assessing the importance of the pro-oxidant potential of air pollution in the development of cardiovascular disease outcomes...
June 29, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28664564/clustering-high-dimensional-mixed-data-to-uncover-sub-phenotypes-joint-analysis-of-phenotypic-and-genotypic-data
#19
D McParland, C M Phillips, L Brennan, H M Roche, I C Gormley
The LIPGENE-SU.VI.MAX study, like many others, recorded high-dimensional continuous phenotypic data and categorical genotypic data. LIPGENE-SU.VI.MAX focuses on the need to account for both phenotypic and genetic factors when studying the metabolic syndrome (MetS), a complex disorder that can lead to higher risk of type 2 diabetes and cardiovascular disease. Interest lies in clustering the LIPGENE-SU.VI.MAX participants into homogeneous groups or sub-phenotypes, by jointly considering their phenotypic and genotypic data, and in determining which variables are discriminatory...
June 30, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28657613/nuts-and-dried-fruits-an-update-of-their-beneficial-effects-on-type-2-diabetes
#20
REVIEW
Pablo Hernández-Alonso, Lucía Camacho-Barcia, Mònica Bulló, Jordi Salas-Salvadó
Nuts and dried fruit are essential foods in the Mediterranean diet. Their frequent consumption has been associated with the prevention and/or the management of such metabolic conditions as type 2 diabetes (T2D), metabolic syndrome and cardiovascular diseases. Several previous reviews of epidemiological studies and clinical trials have evaluated the associations of nuts and/or dried fruit with various metabolic disorders. However, no reviews have focused on the mechanisms underlying the role of nuts and/or dried fruit in insulin resistance and T2D...
June 28, 2017: Nutrients
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