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https://www.readbyqxmd.com/read/28102436/-urethral-stricture-rate-after-prostate-cancer-radiotherapy-five-year-data-of-a-certified-prostate-cancer-center
#1
J Kranz, G Maurer, U Maurer, O Deserno, S Schulte, J Steffens
BACKGROUND: A urethral stricture is a scar of the urethral epithelium which can cause obstructive voiding dysfunction with consequential damage of the upper urinary tract. Almost 45% of all strictures are iatrogenic; they develop in 2-9% of patients after radical prostatectomy, but can also occur after prostate cancer radiotherapy. This study provides 5‑year data of a certified prostate cancer center (PKZ) in terms of urethral strictures. MATERIALS AND METHODS: Between 01/2008 and 12/2012 a total of 519 men were irradiated for prostate cancer (LDR and HDR brachytherapy as well as external beam radiation)...
January 19, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28096921/a-sequential-comparison-of-postoperative-voiding-function-between-two-different-transobturator-sling-procedures
#2
Don Kyoung Choi, Ha Bum Jung, Young Goo Lee, Ki Kyung Kim, Sung Tae Cho
INTRODUCTION: We evaluated sequential postoperative voiding function of two types of sling procedures (Monarc(®) and ALIGN(®)) in patients with stress urinary incontinence. METHODS: Ninety-one women diagnosed with urodynamic stress incontinence were randomly assigned to the study. All enrolled patients underwent Monarc or ALIGN procedure. They were postoperatively evaluated at one day, one week, one month, three months, 12 months, and 24 months. The voiding function was evaluated with uroflowmetry and post-void residual urine...
November 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28078221/testosterone-replacement-therapy-and-voiding-dysfunction
#3
REVIEW
Wesley Baas, Tobias S Köhler
Testosterone replacement therapy (TRT) represents an increasing popular treatment option for men with late-onset hypogonadism (LOH). Because of unsubstantiated beliefs of testosterone's effect on the prostate, the FDA has recently placed a warning on testosterone products, stating that TRT may worsen benign prostatic hyperplasia (BPH). Within this review article we have demonstrated the current understanding of the physiology of testosterone and its relationship with prostatic and lower urinary tract physiology...
December 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28073189/relationship-between-lower-urinary-tract-symptoms-and-inguinal-hernia
#4
Aykut Buğra Sentürk, Musa Ekici, Ibrahim Tayfun Sahiner, Tuncay Tas, Basri Cakiroglu
AIM: To determine the relationship between inguinal hernia (and inguinal hernia subtypes) and low urinary tract symptoms (LUTS) due to benign prostate hyperplasia (BPH), that could be more common than we think. METHOD: The study was designed retrospectively and was done in accordance with the principles of the Declaration of Helsinki, including 100 patients aged > 50 years that were divided into 2 groups: patients with BPH (BPH group) and patients with BPH and inguinal hernia (BPH-IH group 2)...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28053950/lower-urinary-tract-symptoms-prevalence-perceptions-and-healthcare-seeking-behavior-amongst-nigerian-men
#5
Rufus Wale Ojewola, Ezekiel Sofela Oridota, Olanrewaju Samuel Balogun, Ezra Olatunde Ogundare, Taiwo Opeyemi Alabi
PURPOSE: The aim of this study was to determine the prevalence of lower urinary tract symptoms (LUTS) and the factors influencing the healthcare-seeking behavior of men with LUTS. MATERIALS AND METHODS: A cross-sectional survey was performed of 658 men selected using multi-staged sampling techniques. They were interviewed about LUTS and their healthcare-seeking behavior. The data were analysed using PASW Statistics ver. 18. Associations between specific factors and healthcare-seeking behavior were examined using the chi-square and Fisher exact tests...
December 2016: World Journal of Men's Health
https://www.readbyqxmd.com/read/28040503/are-interferential-electrical-stimulation-and-diaphragmatic-breathing-exercises-beneficial-in-children-with-bladder-and-bowel-dysfunction
#6
Vesna D Zivkovic, Ivona Stankovic, Lidija Dimitrijevic, Mirjana Kocic, Hristina Colovic, Marina Vlajkovic, Andjelka Slavkovic, Milica Lazovic
OBJECTIVE: To evaluate the effects of interferential current (IC) stimulation and diaphragmatic breathing exercises (DBE) in children with bladder and bowel dysfunction. PATIENTS AND METHODS: Seventy-nine children with dysfunctional voiding and chronic constipation who were failures of primary care interventions were included in the prospective clinical study. All the children were checked for their medical history regarding LUTS and bowel habits. Physical examination including abdominal and anorectal digital examination were performed...
December 28, 2016: Urology
https://www.readbyqxmd.com/read/28039004/localized-inhibition-of-p2x7r-at-the-spinal-cord-injury-site-improves-neurogenic-bladder-dysfunction-by-decreasing-urothelial-p2x3r-expression-in-rats
#7
Alvaro Munoz, Iman K Yazdi, Xiufeng Tang, Carolina Rivera, Nima Taghipour, Robert G Grossman, Timothy B Boone, Ennio Tasciotti
AIMS: Reestablishment of bladder function in patients with spinal cord injury (SCI) is a clinical priority. Our objectives were to determine whether SCI-localized inhibition of purinergic P2X7 receptors (P2X7R) improve bladder function by decreasing afferent signals mediated by urothelial P2X3R. MAIN METHODS: Systemic inhibition of P2X7R may improve locomotion in rodent SCI models; however, beneficial effects on bladder function and its physiological mechanisms have not been evaluated...
December 27, 2016: Life Sciences
https://www.readbyqxmd.com/read/28035441/continuous-recording-of-intrarectal-pressures-during-the-second-phase-of-labour-correlations-with-postpartum-pelvic-floor-complaints-a-biomechanical-clinical-study
#8
Sylvain Meyer, François Salchli, Patrick Hohlfeld, David Baud, Yvan Vial, Chahin Achtari
INTRODUCTION AND HYPOTHESIS: We correlated intrarectal pressure parameter recordings during the second phase of labour in primiparous women with postpartum pelvic floor (PF) complaints to try to define a critical pressure threshold for the occurrence of permanent PF injury. METHODS: Using a microsystem device, the duration of bearing-down efforts, the area under the pressure curve and the peak pressure during bearing-down efforts were continuously recorded in 43 women with spontaneous delivery (group one) and in 17 women with forceps-assisted delivery (group two)...
December 29, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/28033180/a-woman-with-a-midurethral-sling-and-bladder-outlet-obstruction
#9
Jessica Nelson, Phillipe Zimmern
A midurethral sling is a common procedure for stress urinary incontinence in women. Tensioning of the tape used for the sling is an art, and overtensioning during surgery can lead to obstructive symptoms. A patient with new onset of lower urinary tract symptoms after sling surgery should be evaluated for possible voiding dysfunction. Sling incision does not always correct the obstruction and excision may be needed.
January 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/28012756/vesical-and-ureteral-damage-from-voiding-dysfunction-in-boys-without-neurologic-or-obstructive-disease
#10
Frank Hinman, Franz W Baumann
No abstract text is available yet for this article.
December 21, 2016: Journal of Urology
https://www.readbyqxmd.com/read/28002455/evidence-for-the-role-of-mast-cells-in-cystitis-associated-lower-urinary-tract-dysfunction-a-multidisciplinary-approach-to-the-study-of-chronic-pelvic-pain-research-network-animal-model-study
#11
Xu Wang, Wujiang Liu, Michael O'Donnell, Susan Lutgendorf, Catherine Bradley, Andrew Schrepf, Liwei Liu, Karl Kreder, Yi Luo
Bladder inflammation frequently causes cystitis pain and lower urinary tract dysfunction (LUTD) such as urinary frequency and urgency. Although mast cells have been identified to play a critical role in bladder inflammation and pain, the role of mast cells in cystitis-associated LUTD has not been demonstrated. Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic and debilitating inflammatory condition of the urinary bladder characterized by the hallmark symptoms of pelvic pain and LUTD. In this study we investigated the role of mast cells in LUTD using a transgenic autoimmune cystitis model (URO-OVA) that reproduces many clinical correlates of IC/BPS...
2016: PloS One
https://www.readbyqxmd.com/read/27990752/risk-for-hip-fracture-due-to-alpha-blocker-treatment-in-korean-women-national-health-insurance-database-study
#12
Gi H Seo, Sung R Shim, Hwan W Lee, Jin H Kim, Dong-Il Chun, Hyun J Kim, Hyun Y Lee, Jae H Kim
OBJECTIVE: The aim of this study is to evaluate the risk for hip fracture associated with adverse drug reactions caused by α1-adrenergic (alpha) blockers to treat female voiding dysfunction. METHODS: Information from the Health Insurance Review and Assessment Service database from January 1, 2008 to December 31, 2012 was used. Hip fracture women patients who received a prescription for an alpha blocker due to voiding dysfunction were the cases. A 30-day hazard period after administration of an alpha blocker was set...
December 19, 2016: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/27989639/the-swedish-infant-high-grade-reflux-trial-bladder-function
#13
J Nordenström, U Sillen, G Holmdahl, T Linnér, E Stokland, S Sjöström
INTRODUCTION: It has been suggested that infants with high-grade vesicoureteral reflux (VUR) have lower urinary tract dysfunction (LUTD) that is characterised by large bladder capacity (BC) and increased post-void residual (PVR). However, most of these infants have normal or small BC in early infancy and develop large capacity during the first year of life. OBJECTIVE: This study aimed to see whether LUTD development during the infant years in children with high-grade VUR could be prevented by early reflux resolution...
November 30, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27980522/ultrasound-imaging-in-urogynecology-state-of-the-art-2016
#14
Michał Bogusiewicz
The role of ultrasound imaging in urogynecology is not clearly defined. Despite significant developments in visualization techniques and interpretation of images, pelvic ultrasound is still more a tool for research than for clinical practice. Structures of the lower genitourinary tract and pelvic floor can be visualized from different approaches: transperineal, introital, transvaginal, abdominal or endoanal. According to contemporary guidelines and recommendations, the role of ultrasound in urogynecology is limited to the measurement of post-void residue...
November 2016: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/27958390/prevalence-and-treatment-of-luts-in-patients-with-parkinson-disease-or-multiple-system-atrophy
#15
REVIEW
Teruyuki Ogawa, Ryuji Sakakibara, Sadako Kuno, Osamu Ishizuka, Takeya Kitta, Naoki Yoshimura
The lower urinary tract is controlled by complex neural mechanisms not only in the periphery, but also in the central nervous systems (CNS). Thus, patients with a wide variety of neurological diseases often also have lower urinary tract symptoms (LUTS), including those with Parkinson disease (PD) or multiple system atrophy (MSA). LUTS are common comorbidities associated with both of these neurodegenerative diseases and are likely to impair patients' quality of life. The motor symptoms of PD and MSA often seem similar; however, the pathophysiology, and thus the treatment of LUTS differs considerably...
December 13, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27958325/onabotulinumtoxina-urethral-sphincter-injection-as-treatment-for-non-neurogenic-voiding-dysfunction-a-randomized-double-blind-placebo-controlled-study
#16
Yuan-Hong Jiang, Chung-Cheng Wang, Hann-Chorng Kuo
Non-neurogenic voiding dysfunction including dysfunctional voiding and detrusor underactivity caused by a spastic or non-relaxing external urethral sphincter can theoretically be treated by injections of botulinum A toxin into the external urethral sphincter. This randomized, double-blind, placebo-controlled trial was designed to determine the clinical efficacy of onabotulinumtoxinA urethral sphincter injections in patients with dysfunctional voiding or detrusor underactivity. Patients with medically refractory dysfunctional voiding (n = 31) or detrusor underactivity (n = 31) were randomly allocated in a 2:1 ratio to receive either onabotulinumtoxinA (100 U) (n = 38) or placebo (normal saline) (n = 24)...
December 13, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27928815/comparing-monotherapy-with-tadalafil-or-tamsulosin-and-their-combination-therapy-in-men-with-benign-prostatic-hyperplasia-a-randomized-clinical-trial
#17
Hossein Karami, Amin Hassanzadeh-Hadad, Morteza Fallah-Karkan
PURPOSE: To compare monotherapy with tadalafil or tamsulosin and their combination therapy in men with benignprostatic hyperplasia and erectile dysfunction by comparing IPSS score, prostate volume and Qmax and someother outcomes. MATERIALS AND METHODS: This randomized, single-blind, paralleled group clinical trial was done in 2013 on patientswho had referred to our hospital in Tehran. All patients with lower urinary tract symptoms, benign prostatichyperplasia and any grade of erectile dysfunction were recruited...
8, 2016: Urology Journal
https://www.readbyqxmd.com/read/27921202/endogenous-stem-cells-were-recruited-by-defocused-low-energy-shock-wave-in-treating-diabetic-bladder-dysfunction
#18
Yang Jin, Lina Xu, Yong Zhao, Muwen Wang, Xunbo Jin, Haiyang Zhang
Defocused low-energy shock wave (DLSW) has been shown effects on activating mesenchymal stromal cells (MSCs) in vitro. In this study, recruitment of endogenous stem cells was firstly examined as an important pathway during the healing process of diabetic bladder dysfunction (DBD) treated by DLSW in vivo. Neonatal rats received intraperitoneal injection of 5-ethynyl-2-deoxyuridine (EdU) and then DBD rat model was created by injecting streptozotocin. Four weeks later, DLSW treatment was performed. Afterward, their tissues were examined by histology...
December 5, 2016: Stem Cell Reviews
https://www.readbyqxmd.com/read/27915481/effects-of-combination-treatment-of-alpha-1-adrenergic-receptor-antagonists-on-voiding-dysfunction-study-on-target-organs-in-overactive-bladder-rats
#19
Il Gyu Ko, Bo Min Moon, Sung Eun Kim, Jun Jang Jin, Lakkyong Hwang, Eun Sang Ji, Chang Ju Kim, Tai Hyung Kim, Hyun Hee Choi, Kyung Jin Chung
PURPOSE: Overactive bladder (OAB) causes urinary urgency, usually accompanied by frequency and nocturia. Alpha 1-adrenergic receptor (α1-AR) antagonists are known to improve lower urinary tract symptoms associated with OAB. The α1-AR antagonists constitute a variety of drugs according to the receptor subtype affinity. This study investigated the efficacy of tamsulosin, naftopidil, and a combination of the two on OAB rats. METHODS: The OAB rat model was induced by an intraperitoneal injection of cyclophosphamide for 14 days...
November 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/27889221/the-swedish-infant-high-grade-reflux-trial-study-presentation-and-vesicoureteral-reflux-outcome
#20
Josefin Nordenström, Gundela Holmdahl, Per Brandström, Rune Sixt, Eira Stokland, Ulla Sillén, Sofia Sjöström
INTRODUCTION: High-grade vesicoureteral reflux (VUR) in infants is associated with congenital renal abnormalities, recurrent UTI, and bladder dysfunction. Endoscopic treatment (ET) is a well-established method in children with low to moderate reflux grades, but there is a lack of randomised controlled trials regarding the use of ET versus continuous antibiotic prophylaxis in infants with high-grade VUR. OBJECTIVE: This study aimed to determine whether high-grade VUR in infants can be treated with endoscopic injection and whether ET is superior to antibiotic prophylaxis in the treatment of VUR...
October 24, 2016: Journal of Pediatric Urology
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