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Left colic cancer

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https://www.readbyqxmd.com/read/29577218/-application-of-overlap-method-to-digestive-tract-reconstruction-of-totally-laparoscopic-left-colectomy
#1
Nan Wang, Bobo Zheng, Tao Wu, Qing Qiao, Yulong Zhai, Bo Zhang, Shuai Zhou, Wencong Shi, Xianli He
OBJECTIVE: To investigate the application value of the Overlap method in digestive tract reconstruction of totally laparoscopic left colectomy(TLLC) and its potential advantage. METHODS: The retrospective cohort study was adopted. Clinicopathological data of 16 patients with left colon cancer who underwent TLLC and Overlap anastomosis between August 2016 and August 2017 at Tangdu Hospital were retrospectively collected as Overlap group. Twenty-one patients who underwent laparoscopic assisted left colectomy (LALC) between January 2015 and July 2016 at Tangdu Hospital were used as control (traditional group)...
March 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29577214/-significance-of-the-preservation-of-left-colic-artery-in-laparoscopic-resection-of-rectal-cancer
#2
Xinxiang Li, Qingguo Li
Controversy remains on how to manage left colic artery (LCA) when it comes to laparoscopic proctectomy. With regard to the level of detachment, a high tie of inferior mesenteric artery (IMA) is meant as a ligation at the origin of aorta, while the low tie is the ligation of IMA below the initiation part of left colic artery which is left. Several key points of LCA preservation, including clinical value, oncologic safety and the difficulty of operation, have always been debated. Some scholars hold the point of view that the preservation of LCA will hamper the lymph nodes dissection around the inferior mesenteric artery, resulting in incorrect pathological staging and dismal outcome...
March 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29521825/lymphatic-drainage-of-the-splenic-flexure-defined-by-intraoperative-scintigraphic-mapping
#3
Carolyn E Vasey, Siraj Rajaratnam, Gregory O'Grady, Mike Hulme-Moir
BACKGROUND: The optimal surgical management of splenic flexure cancer is debated, partly because of an incomplete understanding of the lymphatic drainage of this region. OBJECTIVE: This study aimed to evaluate the normal lymphatic drainage of the human splenic flexure using laparoscopic scintigraphic mapping. DESIGN: This was a clinical trial. SETTINGS: The study was conducted at a single tertiary care center. PATIENTS: Thirty consecutive patients undergoing elective colorectal resections without splenic flexure pathology were recruited...
April 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29501795/preservation-versus-non-preservation-of-left-colic-artery-in-sigmoid-and-rectal-cancer-surgery-a-meta-analysis
#4
Yu-Chen Fan, Fei-Long Ning, Chun-Dong Zhang, Dong-Qiu Dai
BACKGROUND: The aim of this study was to conduct a meta-analysis comparing the oncological, intraoperative and safety outcomes in sigmoid and rectal cancer surgery with and without preservation of the left colic artery (LCA). METHOD: We searched Medline, Embase, China National Knowledge Infrastructure (CNKI), and PubMed databases for relevant articles published between 1962 and 2017. Randomized and non-randomized clinical trials were identified and included in the study...
March 1, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29435757/defining-minimal-clearances-for-adequate-lymphatic-resection-relevant-to-right-colectomy-for-cancer-a-post-mortem-study
#5
Jens Marius Nesgaard, Bojan V Stimec, Pricilla Soulie, Bjørn Edwin, Arne Bakka, Dejan Ignjatovic
BACKGROUND: There has been a lengthy discussion on the extent of lymphatic resection for right-sided colon cancer and the central borders of the mesentery that are not yet defined. The objectives of this study are to define minimal clearances for adequate lymphatic resection in regard to colic artery origins and the superior mesenteric artery (SMA) and vein (SMV) relevant to right colectomy. METHODS: Central mesenteric lymph vessels, nodes, and blood vessels were dissected in 16 cadavers...
February 12, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29394796/-optimal-dissection-of-the-intestinal-tract-and-preservation-of-vascular-supply-in-left-hemicolectomy-using-simulation-computed-tomography-colonography
#6
Kazuo Narushima, Hideaki Miyauchi, Gaku Ohira, Kouichi Hayano, Akiko Kagaya, Yorihiko Muto, Shunsuke Imanishi, Yoshihiro Kurata, Yumiko Takahashi, Naoto Sawada, Hiroki Watanabe, Hisahiro Matsubara
Left hemicolectomy is a standard surgical method for cancer of the descending colon. Resection involves the region from the left side of the transverse colon to the sigmoid colon. Although laparoscopic hemicolectomy is widely used, it is difficult to determine an appropriate resection range during surgery because of the limited visual field. Simulation computed tomography colonography(S-CTC), which combines CTC and 3-dimensional vascular imaging, enables the surgeon to clearly identify the position of the primary lesion and dominant vessel...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29381926/the-long-term-survival-benefits-of-high-and-low-ligation-of-inferior-mesenteric-artery-in-colorectal-cancer-surgery-a-review-and-meta-analysis
#7
Dujanand Singh, Jinglong Luo, Xue-Ting Liu, Zinda Ma, Hao Cheng, Yongyang Yu, Lie Yang, Zong-Guang Zhou
BACKGROUND: The decision of ligation at the origin of the inferior mesenteric artery (IMA) or below the origin of the left colic artery (LCA) has remained a dilemma for surgeons in colorectal cancer surgery. The available studies are controversial. The objective of this meta-analysis is to compare the predictive significance of high versus low ligation in colorectal cancer surgery. METHODS: A literature search done using Medline, EMBASE, GoogleScholar, and references...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29203996/metachronous-synchronous-sternal-and-colonic-metastasis-with-asymptomatic-colo-colic-fistula-from-carcinoma-ovary-rare-presentation-of-ovarian-cancer
#8
Srinivas K G, Abid Ali Mirza, Shivananda Swamy, Amarendra S, Gopinath Ks
Ovarian cancer is one of the most common gynecological cancers worldwide. It is the third leading cause of cancer among women in India. Metastatic disease to the visceral organs from ovarian cancer occurs as a terminal event in the natural history of the disease. In particular, spread to the bone and large bowel is infrequently described. The risk of distant metastasis increases in a recurrent setting. We describe a case of a 77-year-old lady, who was diagnosed for ovarian carcinoma in 2007 and underwent primary cytoreductive surgery, stage IIIc...
December 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29178098/-evaluation-of-three-dimensional-ct-reconstruction-on-the-anatomic-variation-of-inferior-mesenteric-artery-and-left-colic-artery
#9
Jiawei Cai, Xiaofeng Wen, Weixing Lin, Zhen He, Dongyun Zhu, Jianping Qiu, Decan Kong, Xiaosheng He, Xiaowen He, Quan Shen, Xiaojian Wu, Ping Lan, Zhiyang Zhou, Jia Ke
OBJECTIVE: To demonstrate the clinical applicability of three-dimensional CT angiography by evaluating the anatomic features and variation of inferior mesenteric artery(IMA) and left colic artery(LCA) in order to provide reference to vessel ligation strategy in laparoscopic rectal cancer surgery. METHODS: Clinical and image data of 123 patients receiving abdominal multislice CT at The Sixth Affiliated Hospital from 2014 to 2015 were retrospectively analyzed. The images were 3D-reconstructed with computer 3D CT angiography and arterial enhancement phase images were chosen for analysis...
November 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29130232/-clinical-study-of-preserving-left-colic-artery-during-laparoscopic-total-mesorectal-excision-for-the-treatment-of-rectal-cancer
#10
Xiaolan You, Yuanjie Wang, Zhiyi Chen, Wenqi Li, Ning Xu, Guiyuan Liu, Xiaojun Zhao, Chuanjiang Huang
OBJECTIVE: To evaluate the feasibility, safety, radicality and short-term outcome of preserving left colic artery (LCA) during laparoscopic total mesorectal excision (TME) for the treatment of rectal cancer. METHODS: From January 2013 to December 2016,136 patients with mid-lower rectal cancer received laparoscopic TME in the Gastrointestinal Surgery Department of Taizhou People's Hospital of Jiangsu Province. Patients with rectal tumor within 10 cm to the anal verge were enrolled into the study...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29075964/strategy-of-laparoscopic-surgery-for-colon-cancer-of-the-splenic-flexure-a-novel-approach
#11
Naoki Matsumura, Hiromi Tokumura, Fumito Saijo, Yu Katayose
BACKGROUND: The splenic flexure (SF) anatomy is complex due to multiple vessels, surrounding organs, layers, and irregular adhesions [1-3]. METHODS: Our laparoscopic approach involves a lateral-to-medial approach to the left-sided transverse mesocolon (TM), a medial-to-lateral approach to the left mesocolon (LM), and take-down of the remnant SF. First, the omental bursa is opened and its posterior wall and the anterior layer of the TM are dissected along the pancreas, where a gauze is placed...
October 26, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28812159/anatomical-and-embryological-perspectives-in-laparoscopic-complete-mesocoloic-excision-of-splenic-flexure-cancers
#12
Takeru Matsuda, Yasuo Sumi, Kimihiro Yamashita, Hiroshi Hasegawa, Masashi Yamamoto, Yoshiko Matsuda, Shingo Kanaji, Taro Oshikiri, Tetsu Nakamura, Satoshi Suzuki, Yoshihiro Kakeji
BACKGROUND: Laparoscopic complete mesocoloic excision (CME) with central vascular ligation for splenic flexure cancer is technically challenging because of its anatomical complexity. Although embryological and anatomical consideration should be helpful to perform CME in colorectal cancer surgery, such studies on the splenic flexure are lacking. METHODS: The splenic flexure is located embryologically between the terminal portion of the midgut and the beginning of the hindgut, and is supplied by the superior mesenteric and inferior mesenteric arteries...
March 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/28733739/variation-and-treatment-of-vessels-in-laparoscopic-right-hemicolectomy
#13
Kai Ye, Jianan Lin, Yafeng Sun, Yiyang Wu, Jianhua Xu, Songbing He
BACKGROUND: With the introduction of complete mesocolic excision (CME) and the application of laparoscopic technique, surgery for colon cancer has become more standardized and the curative effect has improved [1]. The key points in laparoscopic right hemicolectomy are high ligation of main vessels and root dissection of lymph nodes. The wide range of variations in vascular architecture and intraoperative bleeding are common causes of prolonged surgical time, wound hemorrhage, and even transfer to the opening operation...
March 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/28665451/discordance-in-ras-mutations-between-primary-colon-tumor-and-metastases-a-real-event-or-a-matter-of-methodology
#14
Alfonso De Stefano, Mario Rosanova, Umberto Malapelle, Maurizio Martini, Stefano De Falco, Laura Attademo, Giovanni Fiore, Tonia Cenci, Claudio Bellevicine, Sabino De Placido, Giancarlo Troncone, Chiara Carlomagno
BACKGROUND: Analysis of K- and N-RAS mutations is mandatory before planning treatment of metastatic colorectal cancer, because only RAS wild-type (WT) patients can benefit from treatment with anti-EGFR monoclonal antibodies (cetuximab and panitumumab). CASE REPORT: Here we report the case of a 69-year-old male patient affected by metastatic sigmoid cancer. He underwent left hemicolectomy, and histology diagnosed a well-differentiated, pT4, node-positive adenocarcinoma; KRAS analysis performed with direct sequencing identified a mutation in exon 2 of the KRAS gene (GGT->GTT)...
October 31, 2017: International Journal of Biological Markers
https://www.readbyqxmd.com/read/28642452/laparoscopic-treatment-of-colo-colic-intussusception-secondary-to-a-lipomatous-polyp
#15
Carlo V Feo, Daniele Marcello, Claudio F Feo
INTRODUCTION: Colo-colic intussusception is extremely rare in adults and few cases have been described secondary to a lypomatous polyp. CASE REPORT: We present the case of a 50-year old man with chronic abdominal pain who was diagnosed a colo-colic intussusception secondary to a lipoma of the left colon. The patient underwent laparoscopic resection of the splenic flexure without reduction, which occurred spontaneously after induction of the pneumoperitoneum, and final histology confirmed a submucosal lipoma with no evidence of malignancy...
June 12, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28323157/anatomic-variations-of-inferior-mesenteric-artery-and-left-colic-artery-evaluated-by-3-dimensional-ct-angiography-insights-into-rectal-cancer-surgery-a-retrospective-observational-study
#16
Jia Ke, Jiawei Cai, Xiaofeng Wen, Xianrui Wu, Zhen He, Yifeng Zou, Jianping Qiu, Xiaowen He, Xiaosheng He, Lei Lian, Xiaojian Wu, Zhiyang Zhou, Ping Lan
OBJECTIVE: To demonstrate the clinical applicability of 3-dimensional CT angiography (3D-CTA) in evaluating the anatomic variations of inferior mesenteric artery (IMA) and left colic artery (LCA), to help make pre-operative strategies of rectal cancer surgery. METHODS: 188 patients with abdominal and pelvic contrast-enhanced CT scan were retrospectively enrolled and 3D-CTA was reconstructed. The origin and branching patterns of IMA, tracking patterns of LCA, intersectional patterns among IMA, LCA and inferior mesenteric vein (IMV) were examined, and their associations with clinical features were analyzed...
May 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28213788/three-different-approaches-to-the-inferior-mesenteric-artery-during-robotic-d3-lymphadenectomy-for-rectal-cancer
#17
Songphol Malakorn, Tarik Sammour, Brian Bednarski, Yi-Qian Nancy You, George J Chang
BACKGROUND: In rectal cancer surgery, proximal ligation of the inferior mesenteric artery (IMA) with radical lymphadenectomy is the accepted standard of care.1 Our purpose is to describe three different standardized technical approaches for the management of the IMA during D3 lymphadenectomy.2 METHODS: Operative videos of three robotic D3 lymphadenectomy procedures for rectal cancer were reviewed and annotated with schematic anatomical descriptions for clarification. RESULTS: There are three methods for the management of the IMA during D3 lymphadenectomy for rectal cancer...
July 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28133183/-a-patient-with-her2-positive-stage-iv-advanced-gastric-cancer-who-received-chemotherapy-with-trastuzumab-plus-xp-followed-by-conversion-surgery
#18
Kei Yamamoto, Kazuyoshi Yamamoto, Sakae Maeda, Mamoru Uemura, Masakazu Miyake, Naoki Hama, Kazuhiro Nishikawa, Atsushi Miyamoto, Hideyasu Omiya, Michihiko Miyazaki, Masataka Ikeda, Motohiro Hirao, Koji Takami, Shoji Nakamori, Mitsugu Sekimoto
A 68-year-old man presented with type 3 advanced gastric cancer(Circ, tub2>por, HER2 score 3)in the antrum, with skip lesions in the duodenum. The tumor was cT4aN2M1(DUO)CY0, cStage IV . An XP plus trastuzumab regimen(1,000mg/m2 capecitabine[Xeloda®]twice a day on days 1-14, 80mg/m2 CDDP on day 1, 8 mg/m2 trastuzumab on day 1[second course- 6mg/m2])was administered every 3 weeks and repeated for 6 courses without severe adverse events. After 6 courses, the primary tumor and metastatic lymph nodes shrank by 31...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28116666/distal-pancreatectomy-with-celiac-axis-resection-combined-with-reconstruction-of-the-left-gastric-artery
#19
Takafumi Sato, Yosuke Inoue, Yu Takahashi, Yoshihiro Mise, Takeaki Ishizawa, Kenta Tanakura, Hiromichi Ito, Akio Saiura
Distal pancreatectomy with celiac axis resection is one of the most aggressive approaches for the treatment of locally advanced pancreatic cancer with common hepatic artery and/or celiac axis invasion. However, ischemic complications such as ischemic gastropathy and liver failure are problematic. To avoid these complications, we developed left gastric artery-reconstructing distal pancreatectomy with celiac axis resection. We used the middle colic artery for reconstruction. We performed this procedure in 10 patients, using the middle colic artery in three different ways: left branch reconstruction, right branch reconstruction, and reverse reconstruction...
May 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28099070/laparoscopic-rectal-dissection-assisted-by-transanal-endoluminal-videoendoscopy-through-a-blunt-tip-trocar
#20
Emanuele Asti, Andrea Lovece, Luigi Bonavina
BACKGROUND AND AIMS: Laparoscopic resection is a well-established approach for colorectal cancer surgery. In patients with rectal cancer treated by neoadjuvant chemoradiotherapy, it may be difficult to identify a clear safety margin for endostapling and subsequent anastomosis. We designed an innovative technical approach to assist colorectal anastomosis in these patients. TECHNIQUE: A four-trocar laparoscopic approach is used. After exploration of the abdominal cavity, the left colic flexure is completely mobilized...
June 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
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