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https://www.readbyqxmd.com/read/29749883/rapid-sequence-brain-magnetic-resonance-imaging-for-chiari-i-abnormality
#1
James Pan, Jennifer L Quon, Eli Johnson, Bryan Lanzman, Anjeza Chukus, Allen L Ho, Michael S B Edwards, Gerald A Grant, Kristen W Yeom
OBJECTIVE Fast magnetic resonance imaging (fsMRI) sequences are single-shot spin echo images with fast acquisition times that have replaced CT scans for many conditions. Introduced as a means of evaluating children with hydrocephalus and macrocephaly, these sequences reduce the need for anesthesia and can be more cost-effective, especially for children who require multiple surveillance scans. However, the role of fsMRI has yet to be investigated in evaluating the posterior fossa in patients with Chiari I abnormality (CM-I)...
May 11, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29745036/non-small-cell-lung-cancer-brain-metastasis-screening-in-the-era-of-positron-emission-tomography-ct-staging-current-practice-and-outcomes
#2
Mauricio E Diaz, Maciej Debowski, Craig Hukins, David Fielding, Kwun M Fong, Catherine S Bettington
INTRODUCTION: Several clinical guidelines indicate that brain metastasis screening (BMS) should be guided by disease stage in non-small cell lung cancer (NSCLC). We estimate that screening is performed more broadly in practice, and patients undergo brain imaging at considerable cost with questionable benefit. Our aim was to quantify the use and detection rate of BMS in a contemporary cohort staged with 18 F-fluorodeoxyglucose positron emission tomography/computed tomography (PET-CT). METHODS: We conducted a retrospective review of prospectively collected data from three major lung cancer referral centres in Brisbane between January 2011 and December 2015...
May 10, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29729543/craniotomy-for-subdural-hematoma-after-deep-brain-stimulation-surgery-outcomes-and-satisfaction-in-a-case-series-of-two-patients
#3
Gordon Mao, Michael J Gigliotti, Cindy Angle, Donald Whiting, Nestor Tomycz
OBJECTIVE: To determine whether salvage of DBS hardware is beneficial for Parkinson's Disease (PD) patients by looking at follow-up patient's outcomes and satisfaction after their craniotomy operation. PATIENTS AND METHODS: This was a retrospective review of a prospective, single-center deep brain stimulation (DBS) database between 2002-2016 identifying patients with PD who developed subdural hematomas (SDH) due to trauma after their DBS surgery. Of the 636 DBS cases that were performed, 3 PD-DBS patients with significant traumatic SDH managed via craniotomy were identified...
April 27, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29724415/acr-appropriateness-criteria-%C3%A2-orbits-vision-and-visual-loss
#4
Tabassum A Kennedy, Amanda S Corey, Bruno Policeni, Vikas Agarwal, Judah Burns, H Benjamin Harvey, Jenny Hoang, Christopher H Hunt, Amy F Juliano, William Mack, Gul Moonis, Gregory J A Murad, Jeffrey S Pannell, Matthew S Parsons, William J Powers, Jason W Schroeder, Gavin Setzen, Matthew T Whitehead, Julie Bykowski
Visual loss can be the result of an abnormality anywhere along the visual pathway including the globe, optic nerve, optic chiasm, optic tract, thalamus, optic radiations or primary visual cortex. Appropriate imaging analysis of visual loss is facilitated by a compartmental approach that establishes a differential diagnosis on the basis of suspected lesion location and specific clinical features. CT and MRI are the primary imaging modalities used to evaluate patients with visual loss and are often complementary in evaluating these patients...
May 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29718002/vertebral-artery-dissection-masquerading-as-concussion-in-an-adolescent
#5
Gogi Kumar, Bryan Ludwig, Vipul V Patel
OBJECTIVE: Educate providers about the clinical presentation and consequences of delaying diagnosis of traumatic vertebral artery dissection with thromboembolic ischemic strokes in the pediatric population. Vertebral artery dissection is often difficult to diagnose and can be a potentially devastating cause of ischemic stroke. METHODS: Review of the chart, peer review/discussion, and imaging interpretation. RESULTS: A 16-year-old boy was admitted with confusion after a head and neck trauma was sustained while wrestling...
May 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29717567/risk-of-brain-tumor-induction-from-pediatric-head-ct-procedures-a-systematic-literature-review
#6
REVIEW
John P Sheppard, Thien Nguyen, Yasmine Alkhalid, Joel S Beckett, Noriko Salamon, Isaac Yang
Head computed tomography (CT) is instrumental for managing patients of all ages. However, its low dose radiation may pose a low but non-zero risk of tumor induction in pediatric patients. Here, we present a systematic literature review on the estimated incidence of brain tumor induction from head CT exams performed on children and adolescents. MEDLINE was searched using an electronic protocol and bibliographic searches to identify articles related to CT, cancer, and epidemiology or risk assessment. Sixteen studies that predicted or measured head CT-related neoplasm incidence or mortality were identified and reviewed...
April 2018: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29709739/number-of-fractured-calvarial-bones-predicts-outcome-in-traumatic-brain-injury-patients-after-early-craniotomy
#7
Xiaohua Wu, Lingzhe He, Feina Shi, Fei Dong, Qiang Zeng
BACKGROUND: Prognostic markers are important for neurosurgeons to evaluate the indications for aggressive surgical management. The purpose of this study was to investigate whether number of fractured calvarial bones could predict the outcome in TBI patients after early craniotomy. METHODS: TBI patients who underwent early craniotomy were reviewed. The number of fractured calvarial bones was recorded by referring to preoperative CT images. Accordingly, patients were assigned to no calvarial fracture group, single calvarial fracture group, and multiple calvarial fractures group...
April 27, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29698752/differential-effect-of-mild-therapeutic-hypothermia-depending-on-the-findings-of-hypoxic-encephalopathy-on-early-ct-images-in-patients-with-post-cardiac-arrest-syndrome
#8
Mitsuaki Nishikimi, Takayuki Ogura, Kazuki Nishida, Kunihiko Takahashi, Kenji Fukaya, Keibun Liu, Mitsunobu Nakamura, Shigeyuki Matsui, Naoyuki Matsuda
INTRODUCTION: The aim of this study was to evaluate the differential effects of mild therapeutic hypothermia (MTH) in post-cardiac arrest syndrome (PCAS) patients depending on the presence/absence of hypoxic encephalopathy (HE) in the early brain CT images obtained before the initiation of MTH. METHODS: We conducted a retrospective review of the data of a total of 129 patients with PCAS who were treated by MTH (34 °C) or normothermia treatment (NT) (35 °C or 36 °C), and had undergone brain CT examination prior to the initiation of these treatments...
April 23, 2018: Resuscitation
https://www.readbyqxmd.com/read/29685415/preoperative-assessment-of-haemostasis-in-patients-undergoing-stereotactic-brain-biopsy
#9
Christopher Beynon, Shilai Wei, Alexander Radbruch, David Capper, Andreas W Unterberg, Karl L Kiening
Parenchymal hemorrhage is considered a major risk factor for perioperative morbidity in patients undergoing stereotactic brain biopsy. Studies on patients undergoing surgical procedures have suggested that evaluation of prothrombin time (PT) and activated partial thromboplastin time (aPTT) is of limited value with regard to prevention of haemorrhagic complications. However, this issue has not yet been addressed in patients undergoing stereotactic biopsy of intracranial lesions. We retrospectively analysed the medical records of 159 consecutive patients undergoing stereotactic biopsy of supratentorial intracranial lesions during a three-year period...
April 20, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29682018/modern-microsurgical-resection-of-olfactory-groove-meningiomas-by-classical-bicoronal-subfrontal-approach-without-orbital-osteotomies
#10
Ghulam Farooq, Lal Rehman, Irum Bokhari, Syed Raza Hussain Rizvi
Background: The olfactory groove meningioma has always been surgically challenging. The common microscopic surgical procedures exercised involve modification of pterional or sub-frontal approaches with or without orbital osteotomies. However, we believe that orbital osteotomies are not mandatory to achieve gross total resection. Hence, this study was performed to evaluate the surgical outcomes of olfactory groove meningioma with bicoronal sub frontal approach but without orbital osteotomies...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29675632/factors-affecting-mortality-and-reoperations-in-high-energy-pelvic-fractures
#11
Peyman Bakhshayesh, Lars Weidenhielm, Anders Enocson
AIM: Factors affecting mortality during the first year following high-energy pelvic fractures has not been reported previously. Nor has surgical complications leading to reoperations been reported in a cohort with only high-energy pelvic trauma patients. OBJECTIVES: The aim of this study was to report and analyse factors affecting outcome, in terms of mortality and reoperations, up to 1 year after the injury in patients with a traumatic pelvic ring injury due to a high-energy trauma...
April 19, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29674371/automation-of-ct-based-haemorrhagic-stroke-assessment-for-improved-clinical-outcomes-study-protocol-and-design
#12
Betty Chinda, George Medvedev, William Siu, Martin Ester, Ali Arab, Tao Gu, Sylvain Moreno, Ryan C N D'Arcy, Xiaowei Song
INTRODUCTION: Haemorrhagic stroke is of significant healthcare concern due to its association with high mortality and lasting impact on the survivors' quality of life. Treatment decisions and clinical outcomes depend strongly on the size, spread and location of the haematoma. Non-contrast CT (NCCT) is the primary neuroimaging modality for haematoma assessment in haemorrhagic stroke diagnosis. Current procedures do not allow convenient NCCT-based haemorrhage volume calculation in clinical settings, while research-based approaches are yet to be tested for clinical utility; there is a demonstrated need for developing effective solutions...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29674364/health-and-prevention-enhancement-h-peace-a-retrospective-population-based-cohort-study-conducted-at-the-seoul-national-university-hospital-gangnam-center-korea
#13
Changhyun Lee, Eun Kyung Choe, Ji Min Choi, Yunji Hwang, Young Lee, Boram Park, Su Jin Chung, Min-Sun Kwak, Jong-Eun Lee, Joo Sung Kim, Sue Kyung Park, Sang-Heon Cho
PURPOSE: The Health and Prevention Enhancement (H-PEACE) study was designed to investigate the association of diagnostic imaging results, biomarkers and the predisease stage of non-communicable diseases (NCDs), such as malignancies and metabolic diseases, in an average-risk population in Korea. PARTICIPANTS: This study enrolled a large-scale retrospective cohort at the Healthcare System Gangnam Center, Seoul National University Hospital, from October 2003 to December 2014...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29670367/pet-ct-evaluation-of-the-curative-effect-of-crizotinib-on-malignant-myofibroblastoma-with-rare-mutation-of-alk-r401-a-case-report-and-literature-review
#14
Li Yang, Yufeng Wu, Hong Tang, Jiuzhou Zhao, Dongdong Zhao, Sen Yang, Qiming Wang
Objective: The purpose of this article is to explore the targeted treatment of malignant myofibroblastoma and evaluate the role of neoplasm metabolite markers in the evaluation of efficacy after targeted therapy. Method: This report described a case of myofibroblastic sarcoma with rare mutation of ALK R401 in a 58-year-old man prescribed with crizotinib, to evaluate its curative effect by positron emission tomography coupled with computed tomography (PET-CT). After the progressive disease in the brain, bevacizumab combined with crizotinib was administered...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29668333/blood-biomarkers-in-ischemic-stroke-potential-role-and-challenges-in-clinical-practice-and-research
#15
Konstantinos Makris, Alexander Haliassos, Maria Chondrogianni, Georgios Tsivgoulis
Fast and accurate diagnosis of stroke is crucial for the immediate application of the right therapy to patients. However, rapid diagnosis is still a challenge since an ischemic stroke cannot be identified based only on clinical assessment. CT or MRI imaging is required to rule out hemorrhagic stroke since thrombolytic therapy can lead to increased intracranial bleeding and further aggravation of hemorrhagic stroke. In addition, clinical situations that imitate the signs and symptoms of stroke may also impede the rapid diagnosis and treatment of stroke victims...
April 18, 2018: Critical Reviews in Clinical Laboratory Sciences
https://www.readbyqxmd.com/read/29665763/neuroimaging-radiological-interpretation-system-niris-for-acute-traumatic-brain-injury-tbi
#16
Max Wintermark, Ying Li, Victoria Y Ding, Yingding Xu, Bin Jiang, Robyn L Ball, Michael Zeineh, Alisa Gean, Pina Sanelli
To develop an outcome-based NeuroImaging Radiological Interpretation System (NIRIS) for acute traumatic brain injury (TBI) patients that would standardize the interpretation of non-contrast head CTs and consolidate imaging findings into ordinal severity categories that would inform specific patient management actions and that could be used as a clinical decision support tool. We retrospectively identified all patients transported to our emergency department by ambulance or helicopter, for whom a trauma alert was triggered per established criteria and who underwent a non-contrast head CT due to suspicion of TBI, between November 2015 and April 2016...
April 18, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29660554/effect-of-early-brain-infarction-after-subarachnoid-haemorrhage-a-systematic-review-and-meta-analysis
#17
Bruno Gonçalves, Ricardo Turon, Antenor Mendes, Nivea Melo, Paula Lacerda, Pedro Brasil, Fernando Augusto Bozza, Pedro Kurtz, Cassia Righy
OBJECTIVE: Aneurysmal subarachnoid haemorrhage (aSAH) is an acute cerebrovascular event that leads to devastating consequences. Early brain infarction (EBI) develops very early, within the first 72 hours after bleeding, but may have a significant impact on long-term outcomes. The incidence and impact of EBI in the prognosis of aSAH remain uncertain. We performed a systematic review and meta-analysis to evaluate the incidence of EBI in patients with aSAH and determine the effect of EBI on mortality and functional outcomes...
April 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29657889/pre-operative-versus-post-operative-radiosurgery-for-brain-metastasis-effects-on-treatment-volume-and-inter-observer-variability
#18
B A Vellayappan, J Doody, E Vandervoort, J Szanto, J Sinclair, J M Caudrelier, S Malone
Purpose/Objectives: Compared to post-operative whole brain radiotherapy, resection cavity radiosurgery reduces impact on neuro-cognitive function and improves quality-of-life. However, coverage of the operative tract, in addition to tumour bed, may lead to large treatment volumes and inter-observer variability. We hypothesized that pre-operative radiosurgery reduces target volume size and inter-observer variability compared to post-operative radiosurgery. Materials/Methods: We identified 10 consecutive patients, with solitary brain metastasis, treated with post-operative cavity radiosurgery...
2018: Journal of Radiosurgery and SBRT
https://www.readbyqxmd.com/read/29648462/a-systematic-review-of-neuroimaging-findings-in-children-and-adolescents-with-sports-related-concussion
#19
Emilie Chamard, Jonathan D Lichtenstein
BACKGROUND: Sport-related concussion (SRC) generally does not result in structural anomalies revealed through clinical imaging techniques such as MRI and CT. While advanced neuroimaging techniques offer another avenue to investigate the subtle alterations following SRC, the current pediatric literature in this area has yet to be reviewed. The aim of this review is to systematically explore the literature on magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI), functional magnetic resonance imaging (fMRI), and cortical thickness following SRC in children and adolescents...
April 12, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29644298/use-of-idarucizumab-for-dabigatran-reversal-emergency-department-experience-in-two-cases-with-subdural-haematoma
#20
Gail Edwards, Cristina Roman, Rondhir Jithoo, Biswadev Mitra
Introduction: Idarucizumab is the first effective humanized monoclonal antibody fragment developed specifically as a reversal agent for dabigatran, a Direct Oral Anticoagulant. Despite recent trials demonstrating reversal of clinically relevant bleeding, there is a paucity of data on use outside the trial setting. This manuscript describes the use of Idarucizumab to reverse dabigatran in two patients presenting to the emergency department of a major tertiary hospital with acute traumatic subdural haematomas (SDH)...
February 2018: Trauma Case Reports
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