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https://www.readbyqxmd.com/read/28331022/effect-of-non-pharmacological-intervention-for-apathy-response-to-one-on-one-reminiscence-based-intervention
#1
Akira Okada, Tetsuya Ueda
Apathy has adverse consequences for patients and caregivers. However, the therapeutic approach remains uncertain. Here, we present the case of a man aged 67 years who only developed apathy after surgery for oesophageal cancer. He showed no response to intervention with donepezil, a 'brain training' video game and psychoeducation for apathy. Subsequently, we implemented a programme designed to facilitate recall of 2 themes (editorial content and television shows during the week) once a week. After 3 months, the scores of 2 apathy scales rated by the patient's wife, psychological test scores and brain perfusion single-photon emission CT data improved compared with those obtained before intervention...
March 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28321787/a-mathematical-theory-of-shape-and-neuro-fuzzy-methodology-based-diagnostic-analysis-a-comparative-study-on-early-detection-and-treatment-planning-of-brain-cancer
#2
Subrata Kar, D Dutta Majumder
BACKGROUND: Investigation of brain cancer can detect the abnormal growth of tissue in the brain using computed tomography (CT) scans and magnetic resonance (MR) images of patients. The proposed method classifies brain cancer on shape-based feature extraction as either benign or malignant. The authors used input variables such as shape distance (SD) and shape similarity measure (SSM) in fuzzy tools, and used fuzzy rules to evaluate the risk status as an output variable. We presented a classifier neural network system (NNS), namely Levenberg-Marquardt (LM), which is a feed-forward back-propagation learning algorithm used to train the NN for the status of brain cancer, if any, and which achieved satisfactory performance with 100% accuracy...
March 20, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28246520/concurrent-low-brain-and-high-liver-uptake-on-fdg-pet-are-associated-with-cardiovascular-risk-factors
#3
Hyun-Yeol Nam, Sungmin Jun, Kyoungjune Pak, In Joo Kim
OBJECTIVE: Concurrent low brain and high liver uptake are sometimes observed on fluorine-18-labeled fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET). We investigated the potential clinical significance of this uptake pattern related to metabolic syndrome (MS). MATERIALS AND METHODS: We retrospectively reviewed data from 264 consecutive males who had undergone general health check-ups, including FDG PET/CT scans. After an overnight fast, the men had their peripheral blood drawn and the levels of various laboratory parameters measured; an FDG PET/CT scan was performed on the same day...
March 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28237122/a-new-era-for-nuclear-medicine-neuroimaging-in-spain-where-do-we-start-from-in-spain
#4
M A Balsa, V Camacho, P Garrastachu, D García-Solís, M Gómez-Río, S Rubí, X Setoain, J Arbizu
OBJECTIVE: To determine the status of neuroimaging studies of Nuclear Medicine in Spain during 2013 and first quarter of 2014, in order to define the activities of the neuroimaging group of the Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM). MATERIAL AND METHODS: A questionnaire of 14 questions was designed, divided into 3 parts: characteristics of the departments (equipment and professionals involved); type of scans and clinical indications; and evaluation methods...
February 22, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28223249/predicted-unfavorable-neurological-outcome-is-overestimated-by-the-marshall-ct-score-crash-and-impact-models-in-severe-tbi-patients-management-with-early-decompressive-craniectomy
#5
Jose D Charry, Jorman H Tejada, Miguel A Pinzon, Wilson A Tejada, Juan D Ochoa, Manuel Falla, Jesus H Tovar, Ana M Cuellar-Bahamón, Juan P Solano
INTRODUCTION: Traumatic Brain Injury (TBI) is of public health interest and produces significant mortality and disability in Colombia. Calculators and prognostic models have been developed in order to establish neurologic outcome. We tested prognostic models (the Marshall CT score, IMPACT, and CRASH) for 14-day mortality, 6-month mortality, and 6-month outcome in TBI patients in a university Hospital in Colombia. METHODS: A 127 patients' cohort with TBI was treated in a regional trauma center in Colombia over 2 years and Bivariate and Multivariate analyses were used...
February 18, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28209905/diagnostic-value-of-18-f-fdg-pet-ct-versus-mri-in-the-setting-of-antibody-specific-autoimmune-encephalitis
#6
Lilja B Solnes, Krystyna M Jones, Steven P Rowe, Puskar Pattanayak, Abhinav Nalluri, Arun Venkatesan, John C Probasco, Mehrbod Som Javadi
Introduction: Diagnosis of autoimmune encephalitis presents some challenges in the clinical setting due to varied clinical presentations and delay in obtaining antibody panel results. We examined the role of neuroimaging in the setting of autoimmune encephalitides comparing the utility (18)F-FDG PET/CT versus conventional brain imaging with MRI. Methods: A retrospective study was performed assessing the positivity rate of MRI versus (18)F-FDG PET/CT during the initial work-up of 23 patients proven to have antibody positive autoimmune encephalitis...
February 16, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28192877/effect-of-hyperglycemia-on-brain-and-liver-18-f-fdg-standardized-uptake-value-fdg-suv-measured-by-quantitative-positron-emission-tomography-pet-imaging
#7
Benjamin L Viglianti, Ka Kit Wong, Stephanie M Wimer, Aishwarya Paraeswaran, Bin Nan, Christy Ky, Danyelle M Townsend, Domenico Rubello, Kirk A Frey, Milton D Gross
PURPOSE: Blood glucose is routinely measured prior to (18)F-fluorodeoxyglucose (FDG) administration in positron emission tomography (PET) imaging to identify hyperglycemia that may affect image quality. In this study we explore the effects of blood glucose levels upon semi-quantitative standardized uptake value (SUV) measurements of target organs and tissues of interest and in particular address the relationship of blood glucose to FDG accumulation in the brain and liver. METHODS: 436 FDG PET/CT consecutive studies performed for oncology staging in 229 patients (226 male) at the Ann Arbor Veterans Administration Healthcare System were reviewed...
April 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28192624/mr-based-synthetic-ct-generation-using-a-deep-convolutional-neural-network-method
#8
Xiao Han
PURPOSE: Interests have been rapidly growing in the field of radiotherapy to replace CT with magnetic resonance imaging (MRI), due to superior soft tissue contrast offered by MRI and the desire to reduce unnecessary radiation dose. MR-only radiotherapy also simplifies clinical workflow and avoids uncertainties in aligning MR with CT. Methods, however, are needed to derive CT-equivalent representations, often known as synthetic CT (sCT), from patient MR images for dose calculation and DRR-based patient positioning...
February 13, 2017: Medical Physics
https://www.readbyqxmd.com/read/28165328/evaluation-of-mlacf-based-calculated-attenuation-brain-pet-imaging-for-fdg-patient-studies
#9
Harshali Bal, Vladimir Y Panin, Guenther Platsch, Michel Defrise, Charles Hayden, Chloe Hutton, Benjamin Serrano, Benoit Paulmier, Michael E Casey
Calculating attenuation correction for brain PET imaging rather than using CT presents opportunities for low radiation dose applications such as pediatric imaging and serial scans to monitor disease progression. Our goal is to evaluate the iterative time-of-flight based maximum-likelihood activity and attenuation correction factors estimation (MLACF) method for clinical FDG brain PET imaging. FDG PET/CT brain studies were performed in 57 patients using the Biograph mCT (Siemens) four-ring scanner. The time-of-flight PET sinograms were acquired using the standard clinical protocol consisting of a CT scan followed by 10 min of single-bed PET acquisition...
April 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28126030/a-review-of-substitute-ct-generation-for-mri-only-radiation-therapy
#10
REVIEW
Jens M Edmund, Tufve Nyholm
Radiotherapy based on magnetic resonance imaging as the sole modality (MRI-only RT) is an area of growing scientific interest due to the increasing use of MRI for both target and normal tissue delineation and the development of MR based delivery systems. One major issue in MRI-only RT is the assignment of electron densities (ED) to MRI scans for dose calculation and a similar need for attenuation correction can be found for hybrid PET/MR systems. The ED assigned MRI scan is here named a substitute CT (sCT)...
January 26, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28088230/relationship-between-the-uptake-of-18-f-borono-l-phenylalanine-and-l-methyl-11-c-methionine-in-head-and-neck-tumors-and-normal-organs
#11
Yoshiaki Watanabe, Hiroaki Kurihara, Jun Itami, Ryohei Sasaki, Yasuaki Arai, Kazuro Sugimura
BACKGROUND AND PURPOSE: The purpose of this study was to determine the distribution of 4-borono-2-(18)F-fluoro-phenylalanine ((18)F-BPA) and L-[methyl-(11)C] methionine ((11)C-Met) in normal organs and tumors and to evaluate the usefulness of (11)C-Met/PET in screening potential candidates for boron neutron capture therapy (BNCT). MATERIAL METHODS: Seven patients who had at least one histologically confirmed head and neck tumor were included in this study. They underwent both whole-body (18)F-BPA-PET/CT and (11)C-Met-PET/CT within a span of 6 months...
January 14, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28048113/su-f-i-44-using-the-air-signal-to-characterize-image-noise-in-ct
#12
T Szczykutowicz, A Malkus
PURPOSE: With increasing emphasis on CT image quality and low dose, quality activities analyzing noise levels in images will need to be increasingly automated. This work describes a new automated method for characterizing noise in CT. To obviate the need to segment out anatomical structure, this work introduces the use of noise statistics of air to understand the noise in the scanned object. METHODS: Scans of a uniform water phantom were acquired at four dose levels...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048043/su-f-j-212-enabling-conventional-cone-beam-ct-with-the-capability-of-dual-energy-imaging-using-a-simple-add-on-beam-modifier
#13
R Vinke, S Takao, K Umegaki, H Shirato, H Peng, L Xing
PURPOSE: In searching for a robust, efficient and cost-effective dual energy cone beam CT (DECBCT) solution for various radiation oncology applications, in particularly for improved proton dose planning/replanning accuracy and DE-CBCT guided radiation therapy, we investigate a novel energy modulation scheme using a beam modifier placed between the source and patient and optimize its geometric configuration for routine clinical use. METHODS: The study was performed using a Hitachi CBCT scanner and the tube voltage was set at 125 kVp...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047381/su-f-j-213-feasibility-study-of-using-a-dual-energy-cone-beam-ct-decbct-in-proton-therapy-treatment-planning
#14
H Peng, T Kanehira, S Takao, T Matsuura, K Umegaki, H Shirato, L Xing
PURPOSE: The aim of this study is to evaluate the feasibility of using a dual-energy CBCT (DECBCT) in proton therapy treatment planning to allow for accurate electron density estimation. METHODS: For direct comparison, two scenarios were selected: a dual-energy fan-beam CT (high: 140 kVp, low: 80 kVp) and a DECBCT (high: 125 kVp, low: 80 kVp). A Gammex 467 tissue characterization phantom was used, including the rods of air, water, bone (B2-30% mineral), cortical bone (SB3), lung (LN-300), brain, liver and adipose...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046654/mo-fg-campus-jep1-04-evaluating-dect-vs-sect-range-differences-in-proton-therapy-using-clinical-data
#15
N Hudobivnik, F Schwarz, T Johnson, G Dedes, T Tessonnier, F Verhaegen, C Thieke, C Belka, W Sommer, K Parodi, G Landry
PURPOSE: Range uncertainty from X-ray CT number conversion to stopping power ratio (SPR) is one of the key factors limiting the potential of proton therapy. The large margins required for deep seated tumors degrade the organ sparing achievable with the technology. Of interest is the application of dual energy CT (DECT) to SPR estimation. In this planning study proton range differences between SECT and DECT have been quantified for brain cases. METHODS: A last generation dual source DECT scanner was used to acquire SECT (150 kVp with Sn filtration) and DECT (additionally 90 kVp) scans of phantoms and 5 head trauma patients, acting as surrogate cancer patients...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28003608/the-effects-of-misalignment-between-pet-and-ct-scans-on-brain-pet-study-using-ct-based-attenuation-correction-a-phantom-study
#16
Akihide Shimizu, Yusuke Terakawa, Naomi Morita, Kazuhiro Koshino, Hidehiro Iida
PURPOSE: The aim of this study was to evaluate the effects of inaccurate attenuation correction due to the misalignment between the computed tomography (CT)-based μ-map and the positron emission tomography (PET) data on a brain PET. METHODS: CT and PET scans were performed on a 3-dimension (3D) brain phantom, in which the grey matter region was filled with (18)F-fluorodeoxyglucose ((18)F-FDG), and the skull region was filled with/without the bone-equivalent solution...
2016: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/27979380/central-administration-of-neuropeptide-y-differentially-regulates-monoamines-and-corticosterone-in-heat-exposed-fed-and-fasted-chicks
#17
Mohammad A Bahry, Vishwajit S Chowdhury, Hui Yang, Phuong V Tran, Phong H Do, Guofeng Han, Hiromi Ikeda, John F Cockrem, Mitsuhiro Furuse
Recently, we demonstrated that brain neuropeptide Y (NPY) mRNA expression was increased in heat exposed chicks. However, the functions of brain NPY during heat stress are unknown. This study was conducted to investigate whether centrally administered NPY affects food intake, rectal temperature, monoamines, stress hormones and plasma metabolites in chicks under high ambient temperatures (HT). Five or six-day-old chicks were centrally injected with 0, 188 or 375pmol of NPY and exposed to either HT (35±1°C) or a control thermoneutral temperature (CT; 30±1°C) for 3h whilst fed or fasted...
December 6, 2016: Neuropeptides
https://www.readbyqxmd.com/read/27941226/estimating-head-and-neck-tissue-dose-from-x-ray-scatter-to-physicians-performing-x-ray-guided-cardiovascular-procedures-a-phantom-study
#18
Kenneth A Fetterly, Beth A Schueler, Michael P Grams, Glenn M Sturchio
Physicians performing x-ray guided interventional procedures have a keen interest in radiation safety. Radiation dose to tissues and organs of the head and neck are of particular interest because they are not routinely protected by wearable radiation safety devices. This study was conducted to facilitate estimation of radiation dose to tissues of the head and neck of interventional physicians based on the dose recorded by a personal dosimeter worn on the left collar. Scatter beam qualities maximum energy and HVL were measured for 40 scatter beams emitting from an anthropomorphic patient phantom...
March 20, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/27856651/flat-detector-computed-tomography-pbv-map-in-the-evaluation-of-presurgical-embolization-for-hypervascular-brain-tumors
#19
Li-Li Wen, Xin Zhang, Qing-Rong Zhang, Qi Wu, Shu-Juan Chen, Jin-Long Deng, Kaiyi Huang, Han-Dong Wang
BACKGROUND: Preoperative embolization of hypervascular brain tumors is frequently used to minimize intraoperative bleeding. OBJECTIVE: To explore the efficacy of embolization using flat-detector CT (FDCT) parenchymal blood volume (PBV) maps before and after the intervention. MATERIALS AND METHODS: Twenty-five patients with hypervascular brain tumors prospectively received pre- and postprocedural FDCT PBV scans using a biplane system under a protocol approved by the institutional research ethics committee...
November 17, 2016: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/27833318/intracranial-meningioma-mimicking-brain-metastasis-on-18-f-sodium-fluoride-bone-scan-in-a-case-of-carcinoma-cervix
#20
Rollapeta Ramya Priya, Ranadheer Gupta Manthri, Amancharla Yadagiri Lakshmi, Tekchand Kalawat
Bone scintigraphy (BS) is a well--established commonly used imaging modality for staging and follow--up evaluation of cancer patients. Occasionally, BS may show asymptomatic unusual extraosseous lesions in the body which may or may not be related to primary disease. We here present an interesting case of carcinoma cervix in whom (18)F sodium fluoride positron emission tomography-computerized tomography (PET-CT) bone scan detected an intracranial lesion. Initially, this lesion was suspected as brain metastasis; however, later on, combined PET--CT images and contrast-enhanced CT confirmed this lesion as calcified falcine meningioma in the right posterior parietal region...
October 2016: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
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