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https://www.readbyqxmd.com/read/29034771/genome-wide-analysis-of-epstein-barr-virus-identifies-variants-and-genes-associated-with-gastric-carcinoma-and-population-structure
#1
Youyuan Yao, Miao Xu, Liming Liang, Haojiong Zhang, Ruihua Xu, Qisheng Feng, Lin Feng, Bing Luo, Yi-Xin Zeng
Epstein-Barr virus is a ubiquitous virus and is associated with several human malignances, including the significant subset of gastric carcinoma, Epstein-Barr virus-associated gastric carcinoma. Some Epstein-Barr virus-associated diseases are uniquely prevalent in populations with different geographic origins. However, the features of the disease and geographically associated Epstein-Barr virus genetic variation as well as the roles that the variation plays in carcinogenesis and evolution remain unclear. Therefore, in this study, we sequenced 95 geographically distinct Epstein-Barr virus isolates from Epstein-Barr virus-associated gastric carcinoma biopsies and saliva of healthy donors to detect variants and genes associated with gastric carcinoma and population structure from a genome-wide spectrum...
October 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/29029806/-mojito-s-phytophotodermatitis-the-other-lime-disease
#2
Ignacio Torres-Navarro, Eloy Condiño-Brito, Rafael Botella-Estrada
No abstract text is available yet for this article.
October 10, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/29028140/report-of-12-cases-with-tracheobronchial-mucormycosis-and-a-review
#3
Ruoxi He, Chengping Hu, Yongjun Tang, Huaping Yang, Liming Cao, Ruichao Niu
OBJECTIVES: Tranchobronchial mucormycosis is a rare and invasive pulmonary mucormycosis involving the tracheobronchial tree. DATA SOURCE: at a 3500-bed tertiary care center. STUDY SELECTION: This was a retroactive study of 12 cases of tranchobronchial mucormycosis diagnosed in our hospital, and 48 cases that were previously reported in the English literature. RESULTS: Rhizopus was the predominant species of pathogen (66...
October 13, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29023002/dynamics-of-huanglongbing-associated-bacterium-candidatus-liberibacter-asiaticus-in-citrus-aurantifolia-swingle-mexican-lime
#4
Jose Abel Lopez-Buenfil, Jose Abrahan Ramirez-Pool, Roberto Ruiz-Medrano, Maria Del Carmen Montes-Horcasitas, Claudio Chavarin-Palacio, Jesus Moya-Hinojosa, Francisco Javier Trujillo-Arriaga, Rosalia Lira Carmona, Beatriz Xoconostle-Cazares
BACKGROUND: The bacterial disease citrus huanglongbing (HLB), associated with "Candidatus Liberibacter asiaticus" (C.Las) has severely impacted the citrus industry, causing a significant reduction in production and fruit quality. In the present study, it was monitored the C.Las population dynamics in symptomatic, HLB-positive Mexican lime trees (Citrus aurantifolia Swingle) in a tropical, citrus-producing area of Mexico. The objective of this study was to identify the dynamics of the population of huanglongbing-associated bacterium Candidatus Liberibacter asiaticus and its insect vector in Citrus aurantifolia Swingle (Mexican lime)...
2017: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/28992963/transapical-transcatheter-aortic-valve-replacement-with-a-novel-transcatheter-aortic-valve-replacement-system-in-high-risk-patients-with-severe-aortic-valve-diseases
#5
Liming Zhu, Yingqiang Guo, Wei Wang, Huan Liu, Ye Yang, Lai Wei, Chunsheng Wang
OBJECTIVES: The clinical experience of a novel transapical transcatheter aortic valve replacement system, the J-Valve (JC Medical Inc, Burlingame, Calif), in high-risk patients with severe aortic valve diseases is limited. METHODS: A total of 107 high-risk patients (mean age, 74.4 ± 5.2 years) underwent transcatheter aortic valve replacement with the J-Valve from March 2014 to July 2015, which included 63 patients with aortic stenoses and 44 patients with aortic regurgitation...
September 15, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28992085/assessment-of-dna-damage-in-ceramic-workers
#6
Hatice Gul Anlar, Gokce Taner, Merve Bacanli, Servet Iritas, Turker Kurt, Engin Tutkun, Omer Hinc Yilmaz, Nursen Basaran
It is known that ceramic workers are potentially exposed to complex mixture of chemicals such as silica, inorganic lead, lime, beryllium and aluminum that can be associated with an increased risk of several diseases. All operations in the ceramic industries such as mixing, moulding, casting, shaking out and finishing jobs, have been associated with the higher exposure levels and in most of the silica-related industries, average overall exposure exceeded permissible exposure levels for respirable crystalline silica...
July 19, 2017: Mutagenesis
https://www.readbyqxmd.com/read/28986011/trans-generational-changes-and-rural-urban-inequality-in-household-fuel-use-and-cookstove-ventilation-in-china-a-multi-region-study-of-0-5-million-adults
#7
Ka Hung Chan, Kin Bong Hubert Lam, Om P Kurmi, Yu Guo, Derrick Bennett, Zheng Bian, Paul Sherliker, Junshi Chen, Liming Li, Zhengming Chen
BACKGROUND: Disease burden estimates related to household air pollution (HAP) relied on cross-sectional data on cooking fuel, overlooking other important sources (e.g. heating) and temporal-regional variations of exposure in geographically diverse settings. We aimed to examine the trends and variations of for cooking and heating fuel use and ventilation in 500,000 adults recruited from 10 diverse localities of China. METHODS: At baseline (2004-08) and two subsequent resurveys (2008-14), participants of China Kadoorie Biobank, aged 30-79, reported their past and current fuel use for cooking and heating and the availability of cookstove ventilation...
September 28, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28974249/erratum-to-cytokine-and-human-leukocyte-antigen-hla-profile-for-graft-versus-host-disease-gvhd-after-organ-transplantation
#8
Xinhua Chen, Xueqin Meng, Yuning Xu, Haiyang Xie, Shengyong Yin, Hongchun Li, Liming Wu, Shusen Zheng
Following publication of the original article [1], the authors requested a correction in the presentation of their institutions as they appear on the Web of Science. Specifically, it should be emphasized that the institutions belong to Zhejiang University. The correct presentation of affiliations is given in this erratum.
October 3, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/28963102/comprehensive-metabolomic-profiling-and-incident-cardiovascular-disease-a-systematic-review
#9
REVIEW
Miguel Ruiz-Canela, Adela Hruby, Clary B Clish, Liming Liang, Miguel A Martínez-González, Frank B Hu
BACKGROUND: Metabolomics is a promising tool of cardiovascular biomarker discovery. We systematically reviewed the literature on comprehensive metabolomic profiling in association with incident cardiovascular disease (CVD). METHODS AND RESULTS: We searched MEDLINE and EMBASE from inception to January 2016. Studies were eligible if they pertained to adult humans; followed an agnostic and/or comprehensive approach; used serum or plasma (not urine or other biospecimens); conducted metabolite profiling at baseline in the context of examining prospective disease; and included myocardial infarction, stroke, and/or CVD death in the CVD outcome definition...
September 28, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28939702/self-rated-health-status-and-risk-of-ischemic-heart-disease-in-the-china-kadoorie-biobank-study-a-population-based-cohort-study
#10
Wenhong Dong, Xiong-Fei Pan, Canqing Yu, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Tangchun Wu, Zhengming Chen, An Pan, Liming Li
BACKGROUND: Self-rated health (SRH) is a strong predictor of mortality in different populations. However, the associations between SRH measures and risk of ischemic heart disease (IHD) have not been extensively explored, especially in a Chinese population. METHODS AND RESULTS: More than 500 000 adults from 10 cities in China were followed from baseline (2004-2008) through December 31, 2013. Global and age-comparative SRH were reported from baseline questionnaires...
September 22, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28882087/racial-ethnic-disparities-in-quality-of-care-for-cardiovascular-disease-in-ambulatory-settings-a-review
#11
Liming Dong, Oludolapo A Fakeye, Garth Graham, Darrell J Gaskin
Racial and ethnic disparities in cardiovascular disease (CVD) outcomes are widely reported, but research has largely focused on differences in quality of inpatient and urgent care to explain these disparate outcomes. The objective of this review is to synthesize recent evidence on racial and ethnic disparities in management of CVD in the ambulatory setting. Database searches yielded 550 articles of which 25 studies met the inclusion criteria. Reviewed studies were categorized into non-interventional studies examining the association between race and receipt of ambulatory CVD services with observational designs, and interventional studies evaluating specific clinical courses of action intended to ameliorate disparities...
September 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/28878204/analysis-of-antineutrophil-cytoplasm-antibody-from-118-730-patients-in-tertiary-hospitals-in-jiangxi-province-china
#12
Liming Tan, Anjun Jiao, Juanjuan Chen, Xiaojing Feng, Liuyue Xu, Siqi He, Fuyan Tan, Yongqing Jiang, Heng Luo, Hua Li, Yang Wu, Yongjian Tian, Tingting Zeng, Jianlin Yu, Liping Cao, Jianfeng Zheng, Hui Xu, Ming Wei, Wen Gan, Weihua Peng, Yanming Liu, Jing Hou, Jiangxia Xu, LiHua Shuai, Wenzhi Huang, Junyun Huang, Yan Lin, Jianrong Liu
BACKGROUND The discovery of antineutrophil cytoplasm antibody (ANCA) makes the early diagnosis of primary vasculitis possible, and also has important guiding significance for the diagnosis and treatment of secondary vasculitis. This study aimed to investigate the clinical significance of ANCA. MATERIAL AND METHODS ANCA was detected by indirect immunofluorescence assay (IIF), and anti-myeloperoxidase (MPO) antibody, and anti-proteinase 3 (PR3) antibody were detected by ELISA. The results were analyzed retrospectively...
September 7, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28877180/decreased-complexity-of-glucose-dynamics-preceding-the-onset-of-diabetes-in-mice-and-rats
#13
Xiaohua Douglas Zhang, David Pechter, Liming Yang, Xiaoli Ping, Zuliang Yao, Rumin Zhang, Xiaolan Shen, Nina Xiaoyan Li, Jonathan Connick, Andrea R Nawrocki, Manu Chakravarthy, Cai Li
Continuous glucose monitoring (CGM) is a platform to measure blood glucose (BG) levels continuously in real time with high enough resolution to document their underlying fluctuations. Multiscale entropy (MSE) analysis has been proposed as a measure of time-series complexity, and when applied to clinical CGM data, MSE analysis revealed that diabetic patients have lower MSE complexity in their BG time series than healthy subjects. To determine if the clinical observations on complexity of glucose dynamics can be back-translated to relevant preclinical species used routinely in diabetes drug discovery, we performed CGM in both mouse (ob/ob) and rat (Zucker Diabetic Fatty, ZDF) models of diabetes...
2017: PloS One
https://www.readbyqxmd.com/read/28875707/remote-manipulation-of-ligand-nano-oscillations-regulates-adhesion-and-polarization-of-macrophages-in-vivo
#14
Heemin Kang, Sungkyu Kim, Dexter Siu Hong Wong, Hee Joon Jung, Sien Lin, Kaijie Zou, Rui Li, Gang Li, Vinayak P Dravid, Liming Bian
Macrophages play crucial roles in various immune-related responses, such as host defense, wound healing, disease progression, and tissue regeneration. Macrophages perform distinct and dynamic functions in vivo, depending on their polarization states, such as the pro-inflammatory M1 phenotype and pro-healing M2 phenotype. Remote manipulation of the adhesion of host macrophages to the implants and their subsequent polarization in vivo can be an attractive strategy to control macrophage polarization-specific functions but has rarely been achieved...
October 11, 2017: Nano Letters
https://www.readbyqxmd.com/read/28870535/historical-overview-of-infantile-visceral-leishmaniasis-in-el-agamy-alexandria-egypt
#15
REVIEW
Hala A Kassem, John C Beier, Bahira M El Sawaf
Infantile visceral leishmaniasis (IVL) is considered a rare and neglected disease in Egypt. An outbreak of the disease in El Agamy, Alexandria occurred in 1982 although the disease was previously reported 80 years before. Epidemiological and entomological studies were conducted ever since the 1982 outbreak to identify human cases, the parasite, reservoir host and the sand fly vector. Leishmania infantum MON-98, a new and unique zymodeme, was responsible of the disease. Stray dogs acted as the reservoir host and Phlebotomus langeroni was the proven vector...
December 2017: Acta Tropica
https://www.readbyqxmd.com/read/28853497/-vital-pulp-therapy-of-damaged-dental-pulp
#16
Zhou Xuedong, Huang Dingming, Liu Jianguo, Huang Zhengwei, Wei Xin, Yang Deqin, Zhao Jin, Chen Liming, Zhu Lin, Li Yanhong, Li Jiyao
The development of an expert consensus on vital pulp therapy can provide practical guidance for the improvement of pulp damage care in China. Dental pulp disease is a major type of illness that adversely affects human oral health. Pulp capping and pulpotomy are currently the main methods for vital pulp therapy. Along with the development of minimal invasion cosmetic dentistry, using different treatment technologies and materials reasonably, preserving healthy tooth tissue, and extending tooth save time have become urgent problems that call for immediate solution in dental clinics...
August 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28837808/elevated-expression-of-microrna-873-facilitates-th17-differentiation-by-targeting-forkhead-box-o1-foxo1-in-the-pathogenesis-of-systemic-lupus-erythematosus
#17
Lining Liu, Yifan Liu, Min Yuan, Liming Xu, Huanxia Sun
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, and its pathogenesis remains mostly unknown. MicroRNAs (miRs) has drawn much attention as a crucial regulator of autoimmune diseases. In this study, we demonstrated that miR-873 expression was significantly up-regulated in patients with SLE, and its expression was positively associated with the disease severity. CD4(+) T cells, especially the Th17 subset, were found to be the major source of miR-873 expression. Using gain- and loss-of-function approaches, we further showed that miR-873 could facilitate the differentiation of CD4(+) T cells into Th17 lineage...
August 26, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28831106/epidemiological-and-clinical-features-of-primary-giant-cell-tumors-of-the-distal-radium-a-multicenter-retrospective-study-in-china
#18
Hongbin Cao, Fengsong Lin, Yongcheng Hu, Liming Zhao, Xiuchun Yu, Zhen Wang, Zhaoming Ye, Sujia Wu, Shibing Guo, Guochuan Zhang, Jinghua Wang
Giant cell tumors of the distal radius are challenging for surgeons because they are associated with high recurrence rates and poor functional outcomes. Between June 2005 and October 2015, patients with primary giant cell tumors of the distal radius were recruited from seven orthopedic centers in China. The patients' clinical features and demographic characteristics were obtained from medical records and reviewed retrospectively. Overall, 48 cases of giant cell tumors of the distal radius were assessed in this study...
August 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819455/microvesicles-as-potential-biomarkers-for-the-identification-of-senescence-in-human-mesenchymal-stem-cells
#19
Qian Lei, Teng Liu, Fei Gao, Hui Xie, Li Sun, Aiqi Zhao, Wenxiang Ren, Hao Guo, Liming Zhang, Hongxiang Wang, Zhichao Chen, An-Yuan Guo, Qiubai Li
Senescence in human mesenchymal stem cells (MSCs) not only contributes to organism aging and the development of a variety of diseases but also severely impairs their therapeutic properties as a promising cell therapy. Studies searching for efficient biomarkers that represent cellular senescence have attracted much attention; however, no single marker currently provides an accurate cell-free representation of cellular senescence. Here, we studied characteristics of MSC-derived microvesicles (MSC-MVs) that may reflect the senescence in their parental MSCs...
2017: Theranostics
https://www.readbyqxmd.com/read/28819228/convergent-and-divergent-genetic-changes-in-the-genome-of-chinese-and-european-pigs
#20
Jing Wang, Huiying Zou, Lei Chen, Xi Long, Jing Lan, Wenjie Liu, Li Ma, Chao Wang, Xinyu Xu, Liming Ren, Zhenglong Gu, Ning Li, Xiaoxiang Hu, Yaofeng Zhao, Yiqiang Zhao
Since 10,000 BC, continuous human selection has led to intense genetic and phenotypic changes in pig (Sus scrofa) domestication. Through whole genome analysis of 257 individuals, we demonstrated artificial unidirectional and bidirectional selection as the primary force to shape the convergent and divergent changes between Chinese domestic pigs (CHD) and European domestic pigs (EUD). We identified 31 genes in unidirectional selection regions that might be related to fundamental domestication requirements in pigs...
August 17, 2017: Scientific Reports
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