keyword
MENU ▼
Read by QxMD icon Read
search

motor associative plasticity

keyword
https://www.readbyqxmd.com/read/28320257/academic-stress-disrupts-cortical-plasticity-in-graduate-students
#1
Carmen Concerto, Dhaval Patel, Carmenrita Infortuna, Eileen Chusid, Maria R Muscatello, Antonio Bruno, Rocco Zoccali, Eugenio Aguglia, Fortunato Battaglia
Medical education is a time of high stress and anxiety for many graduate students in medical professions. In this study, we sought to investigate the effect of academic stress on cortical excitability and plasticity by using transcranial magnetic stimulation (TMS). We tested two groups (n = 13 each) of healthy graduate medical students (mean age 33.7 ± 3.8 SE). One group was tested during a final exam week (High-stress group) while the other group was tested after a break, during a week without exams (Low-stress group)...
March 20, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28319877/modulating-motor-cortical-neuroplasticity-with-priming-paired-associative-stimulation-in-young-and-old-adults
#2
George M Opie, Aylin K Post, Michael C Ridding, Ulf Ziemann, John G Semmler
OBJECTIVE: To examine the effect of priming paired associative stimulation (PAS) on the modulation of motor cortex (M1) plasticity in young and old adults. METHODS: Fifteen young (20-27yrs) and 15 old (61-79yrs) subjects participated in 3 experimental sessions, with each session involving two consecutive PAS protocols separated by 10mins. The first (priming) protocol was either PASLTP (ISI=N20 latency+2ms), PASLTD (ISI=N20 latency-10ms), or PASControl (ISI=100ms), whereas the second (test) protocol was always PASLTP...
February 28, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28304238/remote-motor-system-metabolic-profile-and-surgery-outcome-in-cervical-spondylotic-myelopathy
#3
Sorin C Craciunas, Mircea R Gorgan, Bogdan Ianosi, Phil Lee, Joseph Burris, Carmen M Cirstea
OBJECTIVE In patients with cervical spondylotic myelopathy (CSM), the motor system may undergo progressive functional/structural changes rostral to the lesion, and these changes may be associated with clinical disability. The extent to which these changes have a prognostic value in the clinical recovery after surgical treatment is not yet known. In this study, magnetic resonance spectroscopy (MRS) was used to test 2 primary hypotheses. 1) Based on evidence of corticospinal and spinocerebellar, rubro-, or reticulospinal tract degeneration/dysfunction during chronic spinal cord compression, the authors hypothesized that the metabolic profile of the primary motor cortices (M1s) and cerebellum, respectively, would be altered in patients with CSM, and these alterations would be associated with the extent of the neurological disabilities...
March 17, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28299208/sensorimotor-cortical-neuroplasticity-in-the-early-stage-of-bell-s-palsy
#4
Wenwen Song, Minhui Dai, Lihua Xuan, Zhijian Cao, Sisi Zhou, Courtney Lang, Kun Lv, Maosheng Xu, Jian Kong
Neuroplasticity is a common phenomenon in the human brain following nerve injury. It is defined as the brain's ability to reorganize by creating new neural pathways in order to adapt to change. Here, we use task-related and resting-state fMRI to investigate neuroplasticity in the primary sensory (S1) and motor cortex (M1) in patients with acute Bell's palsy (BP). We found that the period directly following the onset of BP (less than 14 days) is associated with significant decreases in regional homogeneity (ReHo), fractional amplitude of low frequency fluctuations (fALFF), and intrinsic connectivity contrast (ICC) values in the contralateral S1/M1 and in ReHo and ICC values in the ipsilateral S1/M1, compared to healthy controls...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28290135/spinal-cord-injury-impairs-neurogenesis-and-induces-glial-reactivity-in-the-hippocampus
#5
Ignacio Jure, Luciana Pietranera, Alejandro F De Nicola, Florencia Labombarda
The incorporation of newborn neurons with increased synaptic remodeling and activity-dependent plasticity in the dentate gyrus enhances hippocampal-dependent learning performances. Astrocytes and microglial cells are components of the neurogenic niche and regulate neurogenesis under normal and neurophatological conditions leading to functional consequences for learning and memory. Although cognitive impairments were reported in patients after spinal cord injury (SCI), only few studies have considered remote changes in brain structures which are not related with sensory and motor cortex...
March 13, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28285823/input-specific-plasticity-and-homeostasis-at-the-drosophila-larval-neuromuscular-junction
#6
Zachary L Newman, Adam Hoagland, Krishan Aghi, Kurtresha Worden, Sabrina L Levy, Jun Ho Son, Luke P Lee, Ehud Y Isacoff
Synaptic connections undergo activity-dependent plasticity during development and learning, as well as homeostatic re-adjustment to ensure stability. Little is known about the relationship between these processes, particularly in vivo. We addressed this with novel quantal resolution imaging of transmission during locomotive behavior at glutamatergic synapses of the Drosophila larval neuromuscular junction. We find that two motor input types, Ib and Is, provide distinct forms of excitatory drive during crawling and differ in key transmission properties...
March 22, 2017: Neuron
https://www.readbyqxmd.com/read/28273854/overexpression-of-transforming-acidic-coiled-coil%C3%A2-containing-protein-3-reflects-malignant-characteristics-and-poor-prognosis-of-glioma
#7
Ying Sun, Yu Tian, Guang-Zhi Wang, Shi-Hong Zhao, Bo Han, Yong-Li Li, Chuan-Lu Jiang
Gliomas are malignant primary brain tumors with poor prognosis. Recently, research was indicative of a tight connection between tumor malignancy and genetic alterations. Here, we propose an oncogenic implication of transforming acidic coiled-coil-containing protein 3 (TACC3) in gliomas. By comprehensively analyzing the Chinese glioma genome atlas (CGGA) and publicly available data, we demonstrated that TACC3 were overexpressed along with glioma grade and served as an independent negative prognostic biomarker for glioma patients...
March 4, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28270746/effects-of-repeated-ethanol-exposures-on-nmda-receptor-expression-and-locomotor-sensitization-in-mice-expressing-ethanol-resistant-nmda-receptors
#8
Carolina R den Hartog, Meghin Gilstrap, Bethany Eaton, Daniel H Lench, Patrick J Mulholland, Gregg E Homanics, John J Woodward
Evidence from a large number of preclinical studies suggests that chronic exposure to drugs of abuse, such as psychostimulants or ethanol induces changes in glutamatergic transmission in key brain areas associated with reward and control of behavior. These changes include alterations in the expression of ionotropic glutamate receptors including N-methyl-D-aspartate receptors (NMDAR) that are important for regulating neuronal activity and synaptic plasticity. NMDA receptors are inhibited by ethanol and reductions in NMDA-mediated signaling are thought to trigger homestatic responses that limit ethanol's effects on glutamatergic transmission...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28264978/deletion-of-the-fractalkine-receptor-cx3cr1-improves-endogenous-repair-axon-sprouting-and-synaptogenesis-after-spinal-cord-injury-in-mice
#9
Camila M Freria, Jodie C E Hall, Ping Wei, Zhen Guan, Dana M McTigue, Phillip G Popovich
Impaired signaling via CX3CR1, the fractalkine receptor, promotes recovery after traumatic spinal contusion injury in mice, a benefit achieved in part by reducing macrophage-mediated injury at the lesion epicenter. Here, we tested the hypothesis that CX3CR1-dependent changes in microglia and macrophage functions also will enhance neuroplasticity, at and several segments below the injury epicenter. New data show that in the presence of inflammatory stimuli, CX3CR1-deficient (CX3CR1(-/-)) microglia and macrophages adopt a reparative phenotype and increase expression of genes that encode neurotrophic and gliogenic proteins...
March 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28261504/thalamo-sensorimotor-functional-connectivity-correlates-with-world-ranking-of-olympic-elite-and-high-performance-athletes
#10
Zirui Huang, Henry Hap Davis Iv, Annemarie Wolff, Georg Northoff
Brain plasticity studies have shown functional reorganization in participants with outstanding motor expertise. Little is known about neural plasticity associated with exceptionally long motor training or of its predictive value for motor performance excellence. The present study utilised resting-state functional magnetic resonance imaging (rs-fMRI) in a unique sample of world-class athletes: Olympic, elite, and internationally ranked swimmers (n = 30). Their world ranking ranged from 1st to 250th: each had prepared for participation in the Olympic Games...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28250049/diabetic-polyneuropathy-sensory-neurons-nuclear-structure-and-spliceosome-alterations-a-role-for-cwc22
#11
Masaki Kobayashi, Ambika Chandrasekhar, Chu Cheng, Jose A Martinez, Hilarie Ng, Cristiane de la Hoz, Douglas W Zochodne
Unique deficits in the function of adult sensory neurons as part of their early neurodegeneration might account for progressive polyneuropathy during chronic diabetes mellitus. Here, we provide structural and functional evidence for aberrant pre-mRNA splicing in a chronic type 1 model of experimental diabetic polyneuropathy (DPN). Cajal bodies (CBs), unique nuclear substructures involved in RNA splicing, increased in number in diabetic sensory neurons, but their expected colocalization with survival motor neuron (SMN) proteins was reduced - a mislocalization described in motor neurons of spinal muscular atrophy...
March 1, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28243821/the-impact-of-short-and-long-term-exercise-on-the-expression-of-arc-and-ampars-during-evolution-of-the-6-hydroxy-dopamine-animal-model-of-parkinson-s-disease
#12
P C Garcia, C C Real, L R Britto
The loss of nigral dopaminergic neurons typical in Parkinson's disease (PD) is responsible for hyperexcitability of medium spiny neurons resulting in abnormal corticostriatal glutamatergic synaptic drive. Considering the neuroprotective effect of exercise, the changes promoted by exercise on AMPA-type glutamate receptors (AMPARs), and the role of activity-regulated cytoskeleton-associated protein (Arc) in the AMPARs trafficking, we studied the impact of short and long-term treadmill exercise during evolution of the unilateral 6-hydroxy-dopamine (6-OHDA) animal model of PD...
February 28, 2017: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/28242489/neurosurgery-and-music-the-effect-of-wolfgang-amadeus-mozart
#13
Elena Romana Gasenzer, Ayhan Kanat, Edmund Neugebauer
BACKGROUND: The nervous system works like a great orchestra. Specially the music of Mozart with its´ "Mozart´s effect" is appropriate to use in neurosurgery. The paper investigates the relationship between music and neurosurgery, Mozart´s music in neurosurgical practice. MATERIAL AND METHODS: We used digital catalogues like "pubmed" as well as the libraries of universities. Key words were "Wolfgang Amadeus Mozart", "neurosurgery and music". RESULTS: At the first half of 20 century, neurosurgical approach of some musicians have resulted with fatal outcome such as Maurice Ravel, Josef Hassid,George Gershwin...
February 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28222547/brain-plasticity-after-implanted-peroneal-nerve-electrical-stimulation-to-improve-gait-in-chronic-stroke-patients-two-case-reports
#14
Aurore Thibaut, Florent Moissenet, Carol Di Perri, Céline Schreiber, Angélique Remacle, Elisabeth Kolanowski, Frédéric Chantraine, Claire Bernard, Roland Hustinx, Jean-Flory Tshibanda, Paul Filipetti, Steven Laureys, Olivia Gosseries
BACKGROUND: Recent studies have shown that stimulation of the peroneal nerve using an implantable 4-channel peroneal nerve stimulator could improve gait in stroke patients. OBJECTIVES: To assess structural cortical and regional cerebral metabolism changes associated with an implanted peroneal nerve electrical stimulator to correct foot drop related to a central nervous system lesion. METHODS: Two stroke patients presenting a foot drop related to a central nervous system lesion were implanted with an implanted peroneal nerve electrical stimulator...
February 6, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28220070/neural-correlates-of-mirror-visual-feedback-induced-performance-improvements-a-resting-state-fmri-study
#15
Viola Rjosk, Jöran Lepsien, Elisabeth Kaminski, Maike Hoff, Bernhard Sehm, Christopher J Steele, Arno Villringer, Patrick Ragert
Mirror visual feedback (MVF) is a promising approach to enhance motor performance without training in healthy adults as well as in patients with focal brain lesions. There is preliminary evidence that a functional modulation within and between primary motor cortices as assessed with transcranial magnetic stimulation (TMS) might be one candidate mechanism mediating the observed behavioral effects. Recently, studies using task-based functional magnetic resonance imaging (fMRI) have indicated that MVF-induced functional changes might not be restricted to the primary motor cortex (M1) but also include higher order regions responsible for perceptual-motor coordination and visual attention...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28216127/speaking-related-changes-in-cortical-functional-connectivity-associated-with-assisted-and-spontaneous-recovery-from-developmental-stuttering
#16
Christian A Kell, Katrin Neumann, Marion Behrens, Alexander W von Gudenberg, Anne-Lise Giraud
We previously reported speaking-related activity changes associated with assisted recovery induced by a fluency shaping therapy program and unassisted recovery from developmental stuttering (Kell et al., Brain 2009). While assisted recovery re-lateralized activity to the left hemisphere, unassisted recovery was specifically associated with the activation of the left BA 47/12 in the lateral orbitofrontal cortex. These findings suggested plastic changes in speaking-related functional connectivity between left hemispheric speech network nodes...
February 13, 2017: Journal of Fluency Disorders
https://www.readbyqxmd.com/read/28212832/motor-dysfunction-and-alterations-in-glutathione-concentration-cholinesterase-activity-and-bdnf-expression-in-substantia-nigra-pars-compacta-in-rats-with-pedunculopontine-lesion
#17
Lisette Blanco-Lezcano, Javier Jimenez-Martin, Mei-Li Díaz-Hung, Esteban Alberti-Amador, Maylin Wong-Guerra, Ma Elena González-Fraguela, Bárbara Estupiñán-Díaz, Teresa Serrano-Sánchez, Liliana Francis-Turner, Susana Delgado-Ocaña, Yanier Núñez-Figueredo, Yamilé Vega-Hurtado, Isabel Fernández-Jiménez
Pedunculopontine nucleus (PPN) has been considered a critically important region in the regulation of some of the physiological functions that fail during the progression of Parkinson's disease (PD). In this paper, the effects of unilateral neurotoxic lesion of the PPN [through the injection of N-methyl-d-aspartate (NMDA) solution (concentration: 0.1M; volume: 0.5µL)] in motor execution and gait disorders and the changes in cellular and molecular indicators in rat nigral tissue were evaluated. The motor execution was assessed using the beam test (BT) and the gait disorders by footprint test...
February 15, 2017: Neuroscience
https://www.readbyqxmd.com/read/28197197/fine-motor-skill-training-enhances-functional-plasticity-of-the-corticospinal-tract-after-spinal-cord-injury
#18
Jian Liu, Xiao-Yu Yang, Wei-Wei Xia, Jian Dong, Mao-Guang Yang, Jian-Hang Jiao
Following central nervous system injury, axonal sprouts form distal to the injury site and extend into the denervated area, reconstructing neural circuits through neural plasticity. How to facilitate this plasticity has become the key to the success of central nervous system repair. It remains controversial whether fine motor skill training contributes to the recovery of neurological function after spinal cord injury. Therefore, we established a rat model of unilateral corticospinal tract injury using a pyramidal tract cutting method...
December 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/28190576/field-portable-xrf-reveals-the-ubiquity-of-antimony-in-plastic-consumer-products
#19
Andrew Turner, Montserrat Filella
Very little systematic information exists on the occurrence and concentrations of antimony (Sb) in consumer products. In this study, a Niton XL3t field-portable-X-ray fluorescence (FP-XRF) spectrometer was deployed in situ and in the laboratory to provide quantitative information on Sb dissipated in plastic items and fixtures (including rubber, textile and foamed materials) from the domestic, school, vehicular and office settings. The metalloid was detected in 18% of over 800 measurements performed, with concentrations ranging from about 60 to 60,000μgg(-1)...
April 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28179558/cell-specific-pkm-isoforms-contribute-to-the-maintenance-of-different-forms-of-persistent-long-term-synaptic-plasticity
#20
Jiangyuan Hu, Kerry Adler, Carole Abi Farah, Margaret H Hastings, Wayne S Sossin, Samuel Schacher
Multiple kinase activations contribute to long-term synaptic plasticity, a cellular mechanism mediating long-term memory. The sensorimotor synapse of Aplysia expresses different forms of long-term facilitation (LTF)-nonassociative and associative LTF-that require the timely activation of kinases, including protein kinase C (PKC). It is not known which PKC isoforms in the sensory neuron or motor neuron L7 are required to sustain each form of LTF. We show that different PKMs, the constitutively active isoforms of PKCs generated by calpain cleavage, in the sensory neuron and L7 are required to maintain each form of LTF...
March 8, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
keyword
keyword
110773
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"