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https://www.readbyqxmd.com/read/27893843/comparative-effectiveness-of-smoking-cessation-medications-a-national-prospective-cohort-from-taiwan
#1
Po-Yin Chang, Po-Ching Lo, Hui-Chin Chang, Kuang-Chieh Hsueh, Yi-Wen Tsai
BACKGROUND AND OBJECTIVE: Relative effectiveness of smoking cessation medications-varenicline, bupropion and nicotine replacement therapy (NRT)-remains unclear among smokers in real-world settings. Evidence in females and smokers with light/moderate nicotine dependence is particularly insufficient. This study compared the effectiveness of varenicline, bupropion or NRT gum relative to NRT patch, in achieving abstinence among recent quitters. METHODS: In a national smoking cessation program in Taiwan (2012-2015), a cohort of 11,968 participants received varenicline (n = 5,052), bupropion (n = 823), NRT gum (n = 1944) or NRT patch (n = 4,149)...
2016: PloS One
https://www.readbyqxmd.com/read/27891229/nicotine-replacement-therapy-for-agitation-and-delirium-management-in-the-intensive-care-unit-a-systematic-review-of-the-literature
#2
Melanie Kowalski, Andrew A Udy, Hayden J McRobbie, Michael J Dooley
BACKGROUND: Active smokers are prevalent within the intensive care setting and place a significant burden on healthcare systems. Nicotine withdrawal due to forced abstinence on admission may contribute to increased agitation and delirium in this patient group. The aim of this systematic review was to determine whether management of nicotine withdrawal, with nicotine replacement therapy (NRT), reduces agitation and delirium in critically ill patients admitted to the intensive care unit (ICU)...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27882838/a-pragmatic-randomized-trial-comparing-telephone-based-enhanced-pharmacy-care-and-usual-care-to-support-smoking-cessation
#3
Jason Gong, Christine L Baker, Kelly H Zou, Marianna Bruno, Zhanna Jumadilova, David Lawrence, Beth Wilson, Cynthia Ewel
BACKGROUND: Smoking is the leading preventable cause of death, and tobacco control professionals continue to make progress in cessation efforts. Pharmacists can assist smokers seeking to quit by offering counseling on smoking cessation pharmacotherapies. Pragmatic randomized trials are useful for investigating practical questions about an intervention's risks, benefits, and costs in routine clinical practice. OBJECTIVE: To evaluate an enhanced pharmacy care (EPC) program involving personalized pharmacist-provided telephone counseling for supporting prescription smoking cessation medications compared with usual care (UC)...
December 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27878808/interventions-for-tobacco-use-cessation-in-people-in-treatment-for-or-recovery-from-substance-use-disorders
#4
REVIEW
Dorie Apollonio, Rose Philipps, Lisa Bero
BACKGROUND: Smoking rates in people with alcohol and other drug dependencies are two to four times those of the general population. Concurrent treatment of tobacco dependence has been limited due to concern that these interventions are not successful in this population or that recovery from other addictions could be compromised if tobacco cessation was combined with other drug dependency treatment. OBJECTIVES: To evaluate whether interventions for tobacco cessation are associated with tobacco abstinence for people in concurrent treatment for or in recovery from alcohol and other drug dependence...
November 23, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27851994/pregnancy-outcomes-after-maternal-varenicline-use-analysis-of-surveillance-data-collected-by-the-european-network-of-teratology-information-services
#5
J L Richardson, S Stephens, L M Yates, O Diav-Citrin, J Arnon, D Beghin, A Kayser, D Kennedy, D Cupitt, B Te Winkel, M Peltonen, Y C Kaplan, S H L Thomas
: Varenicline is a smoking cessation aid for which limited data exist concerning safety during human pregnancy. This multicentre prospective observational comparative cohort study was undertaken using surveillance data collected by the European Network of Teratology Information Services. The study sample consisted of 89 varenicline exposed pregnancies and two matched comparator groups; 267 non-teratogen exposed (NTE) controls and 78 exposed to nicotine replacement therapy or bupropion (NRT/B) for smoking cessation...
November 13, 2016: Reproductive Toxicology
https://www.readbyqxmd.com/read/27836982/improving-adherence-to-smoking-cessation-treatment-intervention-effects-in-a-web-based-randomized-trial
#6
Amanda L Graham, George D Papandonatos, Sarah Cha, Bahar Erar, Michael S Amato, Nathan K Cobb, Raymond S Niaura, David B Abrams
BACKGROUND: Web-based smoking cessation interventions can deliver evidence-based treatments to a wide swath of the population, but effectiveness is often limited by insufficient adherence to proven treatment components. This study evaluated the impact of a social network (SN) intervention and free nicotine replacement therapy (NRT) on adherence to evidence-based components of smoking cessation treatment in the context of a Web-based intervention. METHODS: A sample of adult U...
November 11, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/27832565/safety-of-nicotine-replacement-therapy-in-critically-ill-smokers-a-retrospective-cohort-study
#7
A Kerr, J T McVey, A M Wood, Fmp Van Haren
Nicotine replacement therapy (NRT) is a common first-line treatment to prevent nicotine withdrawal in smokers. However, available literature reports conflicting results regarding its efficacy and safety in critically ill patients. The objective of this study was to evaluate the relationship between NRT in smokers in the intensive care unit (ICU) and outcomes. This case-control study was conducted in a university-affiliated tertiary hospital ICU. Over a period of five years, 126 active smokers who received transdermal NRT were matched to 126 active smokers who did not receive NRT...
November 2016: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/27810948/impact-of-a-temporary-nrt-enhancement-in-a-state-quitline-and-web-based-program
#8
Sam Cole, Casey Suter, Chelsea Nash, Joseph Pollard
PURPOSE: To examine the impact of a nicotine replacement therapy (NRT) enhancement on quit outcomes. DESIGN: Observational study using an intent to treat as treated analysis. SETTING: Not available. PARTICIPANTS: A total of 4022 Idaho tobacco users aged ≥18 years who received services from the Idaho Tobacco Quitline or Idaho's web-based program. INTERVENTION: One-call phone or web-based participants were sent a single 4- or 8-week NRT shipment...
November 3, 2016: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/27784123/-cost-effectiveness-of-pharmacological-smoking-cessation-therapies-a-systematic-literature-review
#9
I Aumann, K Rozanski, K Damm, J-M Graf von der Schulenburg
Aim of the Study: Through the promotion of smoking cessation premature mortality can be prevented. Therefore it is necessary to provide effective and cost-effective smoking cessation interventions. In Germany the cost of pharmacological smoking cessation measures are not yet reimbursed by the statutory health insurance. The aim of this study is to present the evidence on the cost-effectiveness of already approved pharmacological smoking cessation therapies and to evaluate their quality. Method: A systematic literature research was conducted in the databases by DIMDI (Medline, Embase, etc...
October 2016: Das Gesundheitswesen
https://www.readbyqxmd.com/read/27780910/radiological-and-nrt-ratio-based-estimation-of-slim-straight-cochlear-implant-electrode-positions-a-multicenter-study
#10
Philipp Mittmann, Ingo Todt, Arneborg Ernst, Grit Rademacher, Sven Mutze, Sophia Göricke, Marc Schlamann, Stephan Lang, Diana Arweiler-Harbeck, Florian Christov
OBJECTIVES: An intraoperative neural response telemetry-ratio (NRT-ratio) was established, which can provide information about the intraoperative intracochlear electrode array position for perimodiolar electrodes. METHODS: In a retrospective controlled study in 2 tertiary referral centers, the electrophysiological data sets of 50 patients with measured intraoperative auto-NRTs and postoperative radiological examinations were evaluated. All patients were implanted with Nucleus slim straight electrodes...
January 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27759475/cessation-strategies-young-adult-smokers-use-after-participating-in-a-facebook-intervention
#11
Johannes Thrul, Danielle E Ramo
BACKGROUND: Young adults underutilize current evidence-based smoking cessation strategies; yet social media are widely used and accepted among this population. A better understanding of whether and how young adults try to quit smoking in the context of a social media smoking cessation intervention could inform future intervention improvements. OBJECTIVES: We examined frequency, strategies used, and predictors of self-initiated 24-hour quit attempts among young adults participating in a Facebook intervention...
October 19, 2016: Substance Use & Misuse
https://www.readbyqxmd.com/read/27754739/retreatment-with-varenicline-is-a-cost-effective-aid-for-smoking-cessation
#12
Kirsi Kautiainen, Heikki Ekroos, Mikko Puhakka, Helena Liira, Juha Laine, Kari Linden, Jarmo Hahl
OBJECTIVE: One quit attempt with varenicline has been found to be a cost-effective smoking cessation intervention. The purpose of this study was to analyze varenicline's cost-effectiveness in patients who relapse during or after the first treatment. A comparison was made between retreatment schema with varenicline and retreatment schema with bupropion, NRT and unaided cessation, and treatment once with varenicline in a Finnish context. METHODS: The two-quit version of BENESCO Markov model was used to follow a cohort of smokers making up to two quit attempts over a lifetime...
October 18, 2016: Journal of Medical Economics
https://www.readbyqxmd.com/read/27740935/a-novel-grade-lymph-node-ratio-model-predicts-the-prognosis-of-the-advanced-gastric-cancer-patients-after-neoadjuvant-radiotherapy
#13
Jianjun Liu, Mingxue Su, Jing Wang, Gan Zhang, Jing Zhou, Anqing Zhang, Zixue Ren, Xucai Zheng, Shikai Hong, Shengying Wang, Rongxin Zhang
Although local advanced gastric cancer (AGC) could benefit from neoadjuvant radiotherapy (NRT), there are few studies evaluating patients' survival after NRT. In current study, we aimed to investigate the value of prognostic factors in AGC patients after NRT and to evaluate whether post-therapy pathological characteristics were predictive factors in these patients. We retrospectively analyzed AGC patients who underwent NRT from Surveillance, Epidemiology, and End Results (SEER) Database. The patients' clinical and post-therapy pathological characteristics were analyzed...
October 11, 2016: Oncotarget
https://www.readbyqxmd.com/read/27734465/interventions-to-reduce-harm-from-continued-tobacco-use
#14
REVIEW
Nicola Lindson-Hawley, Jamie Hartmann-Boyce, Thomas R Fanshawe, Rachna Begh, Amanda Farley, Tim Lancaster
BACKGROUND: Although smoking cessation is currently the only guaranteed way to reduce the harm caused by tobacco smoking, a reasonable secondary tobacco control approach may be to try and reduce the harm from continued tobacco use amongst smokers unable or unwilling to quit. Possible approaches to reduce the exposure to toxins from smoking include reducing the amount of tobacco used, and using less toxic products, such as pharmaceutical, nicotine and potential reduced-exposure tobacco products (PREPs), as an alternative to cigarettes...
October 13, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27734062/successes-and-unintended-consequences-of-the-northern-territory-s-smoke-free-prisons-policy-results-from-a-process-evaluation
#15
Marita Hefler, Robyn Hopkins, David P Thomas
OBJECTIVES: In 2013, the Northern Territory was the first Australian jurisdiction to introduce a smoke-free policy for all correctional facilities. We report on a process evaluation to identify what worked well, key challenges and unintended consequences. METHODS: We interviewed 87 people, comprising remand, medium-security and low-security prisoners; visiting family members; and prison staff (including prison management and health workers). A realist evaluation approach was used...
April 15, 2016: Public Health Research & Practice
https://www.readbyqxmd.com/read/27733658/postnatal-cardiovascular-consequences-in-the-offspring-of-pregnant-rats-exposed-to-smoking-and-smoking-cessation-pharmacotherapies
#16
Kathirvel Gopalakrishnan, Amar S More, Gary D Hankins, Tatiana N Nanovskaya, Sathish Kumar
Approximately 20% of pregnant women smoke despite intentions to quit. Smoking cessation drugs, such as nicotine replacement therapy (NRT) and bupropion, are recommended treatments. Adverse cardiovascular outcomes in offspring have raised concerns about NRT's safety during pregnancy. However, the effect of bupropion is unknown. Using a rat model, we determined whether NRT and bupropion interventions during pregnancy are safer than continued smoking on offspring's cardiovascular function. Male offspring of controls and dams exposed to cigarette smoke (1...
October 12, 2016: Reproductive Sciences
https://www.readbyqxmd.com/read/27722308/direct-photoisomerization-of-ch2i2vs-chbr3-in-the-gas-phase-a-joint-50-fs-experimental-and-multireference-resonance-theoretical-study
#17
Veniamin A Borin, Sergey M Matveev, Darya S Budkina, Patrick Z El-Khoury, Alexander N Tarnovsky
Femtosecond transient absorption measurements powered by 40 fs laser pulses reveal that ultrafast isomerization takes place upon S1 excitation of both CH2I2 and CHBr3 in the gas phase. The photochemical conversion process is direct and intramolecular, i.e., it proceeds without caging media that have long been implicated in the photo-induced isomerization of polyhalogenated alkanes in condensed phases. Using multistate complete active space second order perturbation theory (MS-CASPT2) calculations, we investigate the structure of the photochemical reaction paths connecting the photoexcited species to their corresponding isomeric forms...
October 10, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27716223/gender-difference-and-effect-of-pharmacotherapy-findings-from-a-smoking-cessation-service
#18
N J Walker, H C van Woerden, V Kiparoglou, Y Yang, H Robinson, E Croghan
BACKGROUND: Smoking cessation services are available in England to provide assistance to those wishing to quit smoking. Data from one such service were analysed in order to investigate differences in quit rate between males and females prescribed with different treatments. METHODS: A logistic regression model was fitted to the data using the binary response of self-reported quit (failed attempt = 0, successful attempt = 1), validated by Carbon Monoxide (CO) monitoring, 4 weeks after commencing programme...
October 3, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27703601/in-vitro-evaluation-of-efficacy-of-different-rotary-instrument-systems-for-gutta-percha-removal-during-root-canal-retreatment
#19
Mercy Joseph, Jyoti Ahlawat, Amit Malhotra, Murali Rao, Abhimanyu Sharma, Sangeeta Talwar
BACKGROUND: Complete removal of old filling material during root canal retreatment is fundamental for predictable cleaning and shaping of canal anatomy. Most of the retreatment methods tested in earlier studies have shown inability to achieve complete removal of root canal filling. Therefore the aim of this investigation was to assess the efficacy of three different rotary nickel titanium retreatment systems and Hedstrom files in removing filling material from root canals. MATERIAL AND METHODS: Sixty extracted mandibular premolars were decoronated to leave 15 mm root...
October 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27699443/a-systematic-review-of-possible-serious-adverse-health-effects-of-nicotine-replacement-therapy
#20
Peter N Lee, Marc W Fariss
We conducted a systematic literature review to identify and critically evaluate studies of serious adverse health effects (SAHEs) in humans using nicotine replacement therapy (NRT) products. Serious adverse health effects refer to adverse events, leading to substantial disruption of the ability to conduct normal life functions. Strength of evidence evaluations and conclusions were also determined for the identified SAHEs. We evaluated 34 epidemiological studies and clinical trials, relating NRT use to cancer, reproduction/development, CVD, stroke and/or other SAHEs in patients, and four meta-analyses on effects in healthy populations...
October 3, 2016: Archives of Toxicology
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