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https://www.readbyqxmd.com/read/28399192/genome-wide-identification-classification-and-transcriptional-analysis-of-nitrate-and-ammonium-transporters-in-coffea
#1
Tiago Benedito Dos Santos, Joni Esrom Lima, Mariane Silva Felicio, João Danillo Moura Soares, Douglas Silva Domingues
Nitrogen (N) is quantitatively the main nutrient required by coffee plants, with acquisition mainly by the roots and mostly exported to coffee beans. Nitrate (NO3-) and ammonium (NH4+) are the most important inorganic sources for N uptake. Several N transporters encoded by different gene families mediate the uptake of these compounds. They have an important role in source preference for N uptake in the root system. In this study, we performed a genome-wide analysis, including in silico expression and phylogenetic analyses of AMT1, AMT2, NRT1/PTR, and NRT2 transporters in the recently sequenced Coffea canephora genome...
April 10, 2017: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/28398690/use-of-nicotine-replacement-therapy-in-young-people-entering-custody-in-new-south-wales-australia
#2
Leigh Haysom, Dianne Lawrence, Donna Mellish, Peter Burns, Pariza Khale, Ariana Arulampalam, Catherine Stapylton
AIM: To describe the prevalence of nicotine dependence and acceptance of nicotine replacement therapy (NRT) in young people entering custody, where smoking is not allowed. METHODS: Cross-sectional study in 2013. SETTING: All New South Wales Juvenile Justice Centres. PARTICIPANTS: Incarcerated youth, aged 12-21 years. MAIN EXPOSURES: gender, age, ethnicity, cannabis use. MAIN OUTCOMES: rates of smoking, cannabis use, nicotine dependence, NRT acceptance...
April 11, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28395126/mapping-the-trajectory-of-nucleophilic-substitution-at-silicon-using-a-peri-substituted-acenaphthyl-scaffold
#3
Emanuel Hupf, Marian Olaru, Ciprian I Rat, Christian B Hübschle, Enno Lork, Simon Grabowsky, Stefan Mebs, Jens Beckmann
The nucleophilic substitution reaction of second order (SN2) at a silicon atom is scrutinized using snapshots along a pseudo-reaction coordinate. Phosphine and fluoride represent both attacking and leaving groups in the modeled SN2 reaction. In the experimentally obtained 5-Ph2P-Ace-6-SiMe2F (1) the phosphine moiety and the fluorosilane moiety are forced into immediate proximity through an acenaphthyl scaffold, i.e. they exhibit peri-interactions that serve as the model of the reactant ion-molecule complex and starting point for a theoretical PES scan...
April 10, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28386232/transcriptomic-profiles-reveal-the-interactions-of-cd-zn-in-dwarf-polish-wheat-triticum-polonicum-l-roots
#4
Yi Wang, Xiaolu Wang, Chao Wang, Fan Peng, Ruijiao Wang, Xue Xiao, Jian Zeng, Houyang Kang, Xing Fan, Lina Sha, Haiqin Zhang, Yonghong Zhou
Different intra- or interspecific wheat show different interactions of Cd/Zn. Normally, Zn has been/being widely utilized to reduce the Cd toxicity. In the present study, the DPW seedlings exhibited strong Cd tolerance. Zn and Cd mutually inhibited their uptake in the roots, showed antagonistic Cd/Zn interactions. However, Zn promoted the Cd transport from the roots to shoots, showed synergistic. In order to discover the interactive molecular responses, a transcriptome, including 123,300 unigenes, was constructed using RNA-Sequencing (RNA-Seq)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28376818/smokers-making-a-quit-attempt-using-e-cigarettes-with-or-without-nicotine-or-prescription-nicotine-replacement-therapy-impact-on-cardiovascular-function-isme-nrt-a-study-protocol
#5
Markos Klonizakis, Helen Crank, Anil Gumber, Leonie S Brose
BACKGROUND: The estimated number of cigarette smokers in the world is 1.3 billion, expected to rise to 1.7 billion by 2025, with 10 million smokers living in the U.K. Smoking is the leading, preventable death-cause worldwide, being responsible for almost 650,000 deaths in the E.U. annually. A combination of pharmacological interventions, including nicotine replacement therapy, bupropion and varenicline, and behavioural support is the most effective approach to smoking cessation. However, even the best methods have high relapse rates of approximately 75% within 6 months...
April 4, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28345689/can-there-be-a-multi-bond-between-noble-gas-and-metal-a-theoretical-study-of-f2xemof2
#6
Kunqi Gao, Li Sheng
A new noble gas compound containing a Xe-Mo double bond, F2XeMoF2, was theoretically constructed and studied based on DFT and ab initio calculations. The CCSD(T)-calculated Xe-Mo bond length of 2.518 Å was comparable to the standard value of 2.56 Å. The bonding energy (32.3 kcal mol(-1)) was even higher than that of the Xe-Au bond in the well-known XeAuF complex (24.1 kcal mol(-1)). The result of natural bond orbital (NBO) analysis indicates that there is a σ-bond and a π-bond between the Xe and Mo atoms in F2XeMoF2...
March 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28342700/nicotine-replacement-therapy-in-patients-with-aneurysmal-subarachnoid-hemorrhage-systematic-review-of-the-literature-and-survey-of-canadian-practice
#7
REVIEW
Ricky D Turgeon, Stephano J Chang, Charlotte Dandurand, Peter A Gooderham, Camille Hunt
Tobacco smoke increases the risk of aneurysmal subarachnoid hemorrhage (SAH), as well as complications such as vasospasm. Most patients presenting with aneurysmal SAH smoke, and many survivors continue to smoke after discharge. Neurosurgeons often hesitate to use nicotine replacement therapy (NRT) during hospitalization of patients with SAH due to concerns of inducing vasospasm. We aimed to evaluate the safety and efficacy, and patterns of use of NRT in smokers hospitalized for SAH. We performed a systematic review of MEDLINE, CENTRAL, Embase, and unpublished sources of literature to October 2016 for randomized and observational studies comparing exposure to non-exposure of smoking cessation products in the acute phase of aneurysmal SAH...
March 22, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28340053/does-the-regulatory-environment-for-e-cigarettes-influence-the-effectiveness-of-e-cigarettes-for-smoking-cessation-longitudinal-findings-from-the-itc-four-country-survey
#8
Hua-Hie Yong, Sara C Hitchman, K Michael Cummings, Ron Borland, Shannon M L Gravely, Ann McNeill, Geoffrey T Fong
Introduction: To date, no studies have explored how different regulatory environments may influence the effectiveness of ECs as a smoking cessation aid. Objective: This study compares the real-world effectiveness of adult smokers using ECs for quitting compared with quitting unassisted or quitting with NRT and/or prescription medications in two countries with restrictive policies towards ECs (i.e., Canada and Australia) versus two countries with less restrictive policies (i...
March 4, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28283849/long-term-outcome-after-endoscopic-submucosal-dissection-for-early-gastric-cancer-in-non-neoplastic-pathology-results
#9
Yong Hwan Kwon, Seong Woo Jeon, Su Youn Nam, Hyun Seok Lee, Jeong Shik Kim, Ji Young Park
BACKGROUND: After endoscopic submucosal dissection (ESD) for early gastric cancer (EGC), negative pathological findings cause concern about the adequacy of the procedure and local recurrence after ESD. AIM: To investigate the incidence of local recurrence in cases with negative pathological findings after ESD for EGC and pathologically complete resection (CR) during long-term follow-up. METHODS: We reviewed 453 patients who underwent ESD for ECG from January 2007 to December 2010, respectively...
May 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28273510/effects-of-cadmium-resistant-fungi-aspergillus-aculeatus-on-metabolic-profiles-of-bermudagrass-cynodondactylon-l-pers-under-cd-stress
#10
Xiaoning Li, Margaret Mukami Gitau, Shijuan Han, Jinmin Fu, Yan Xie
Plants' tolerance to heavy metal stress may be induced by the exploitation of microbes. The objectives of this study were to investigate the effect of cadmium (Cd)-resistant fungus, Aspergillus aculeatus, on tolerance to Cd and alteration of metabolites in bermudagrass under Cd stress, and identify the predominant metabolites associated with Cd tolerance. Two genotypes of bermudagrass with contrasting Cd tolerance (Cd-sensitive 'WB92' and Cd-tolerant 'WB242') were exposed to 0, 50, 150 and 250 mg kg(-1) Cd for 21 days...
February 20, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28257667/combination-nicotine-replacement-therapy-strategies-for-initiation-and-tapering
#11
Stephanie L Hsia, Mark G Myers, Timothy C Chen
Several studies and meta-analyses have demonstrated the efficacy of combination nicotine replacement therapy (NRT) for patients who wish to quit smoking. However, there is limited guidance with respect to initiation and tapering of combination NRT. We attempt to review the evidence and rationale behind combination NRT, present the dosing used in combination NRT studies, and propose a step-down approach for tapering of combination NRT with integration of behavioral strategies.
April 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28239942/extended-treatment-for-cigarette-smoking-cessation-a-randomized-control-trial
#12
Jennifer R Laude, Steffani R Bailey, Erin Crew, Ann Varady, Anna Lembke, Danielle McFall, Anna Jeon, Diana Killen, Joel D Killen, Sean P David
AIM: To test the potential benefit of extending cognitive-behavioral therapy (CBT) relative to not extending CBT on long-term abstinence from smoking. DESIGN: Two-group parallel randomised controlled trial. Patients were randomized to receive non-extended CBT (n = 111) or extended CBT (n = 112) following a 26-week open-label treatment. SETTING: Community clinic in the USA. PARTICIPANTS: 219 smokers (mean age: 43 years; mean cigarettes/day: 18)...
February 26, 2017: Addiction
https://www.readbyqxmd.com/read/28215231/use-of-varenicline-in-smokeless-tobacco-cessation-influences-sleep-quality-and-dream-recall-frequency-but-not-dream-affect
#13
Francesca Polini, Rosastella Principe, Serena Scarpelli, Francesca Clementi, Luigi De Gennaro
OBJECTIVE: Varenicline (VCL) treatment has become popular as a part of smoking-cessation therapies, even though its possible implications in neuropsychiatric adverse events include abnormal sleep and nightmares. Our study is the first aimed at prospectively investigating changes in sleep and dream measures across such treatment by using a one week sleep diary and collecting dream recall (DR). METHODS: Thirty-eight smokers participated in two different effective smoking-cessation programs: 25 subjects received VCL, 13 subjects received nicotine replacement therapy (NRT)...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28212652/a-mixed-methods-feasibility-study-of-nicotine-assisted-smoking-reduction-programmes-delivered-by-community-pharmacists-the-redpharm-study
#14
Amanda Farley, Sarah Tearne, Taina Taskila, Rachel H Williams, Susan Mackaskill, Jean-Francois Etter, Paul Aveyard
BACKGROUND: Pivotal trials have established that, among people who have no immediate intention to quit smoking, nicotine replacement therapy (NRT) helps people reduce and eventually stop smoking. The prime aim of this trial was to investigate the feasibility of implementing such a programme in community pharmacies. In addition, we investigated the effectiveness of providing behavioural support compared with self-help methods and of shorter compared with standard length reduction programmes...
February 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28208227/integrating-remotely-sensed-fires-for-predicting-deforestation-for-redd
#15
Dolors Armenteras, Cerian Gibbes, Jesús A Anaya, Liliana M Dávalos
Fire is an important tool in tropical forest management, as it alters forest composition, structure, and the carbon budget. The United Nations program on Reducing Emissions from Deforestation and Forest Degradation (REDD+) aims to sustainably manage forests, as well as to conserve and enhance their carbon stocks. Despite the crucial role of fire management, decision-making on REDD+ interventions fails to systematically include fires. Here, we address this critical knowledge gap in two ways. First, we review REDD+ projects and programs to assess the inclusion of fires in monitoring, reporting, and verification (MRV) systems...
February 16, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28207556/clinicopathological-characteristics-of-patients-who-underwent-additional-gastrectomy-after-incomplete-endoscopic-resection-for-early-gastric-cancer
#16
Jae Jin Hwang, Dong Ho Lee, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim
To evaluate the clinicopathological characteristics and factors that lead to residual tumors in patients who underwent additional gastrectomy for incomplete endoscopic resection (ER) for early gastric cancer (EGC).Between 2003 and 2013, the medical records of patients underwent additional gastrectomy after incomplete ER were retrospectively reviewed. Those diagnosed with the presence of histologic residual tumor in specimens obtained by gastrectomy were assigned to the residual tumor (RT) group (n = 47); those diagnosed with the absence of histologic residual tumor were assigned to the nonresidual tumor (NRT) group (n = 33)...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28192615/the-impact-of-tv-mass-media-campaigns-on-calls-to-a-national-quitline-and-the-use-of-prescribed-nicotine-replacement-therapy-a-structural-vector-autoregression-analysis
#17
Houra Haghpanahan, Daniel F Mackay, Jill P Pell, David Bell, Tessa Langley, Sally Haw
AIMS: To estimate (1) the immediate impact; (2) the cumulative impact; and (3) the duration of impact of Scottish tobacco control TV mass media campaigns (MMCs) on smoking cessation activity, as measured by calls to Smokeline and the volume of prescribed nicotine replacement therapy (NRT). DESIGN: Multivariate time-series analysis using secondary data on population level measures of exposure to TV MMCs broadcast and smoking cessation activity between 2003 and 2012...
February 13, 2017: Addiction
https://www.readbyqxmd.com/read/28182446/factor-structure-of-the-smoking-cessation-self-efficacy-questionnaire-among-smokers-with-and-without-a-psychiatric-diagnosis
#18
Matthew Clyde, Andrew Pipe, Charl Els, Robert Reid, Heather Tulloch
Cessation self-efficacy has been shown to be a consistent predictor of smoking cessation outcomes. To date, no scale assessing cessation self-efficacy has been validated across smokers with and without a psychiatric diagnosis (current or past). Smokers with a psychiatric diagnosis are typically heavy smokers, have a more difficult time quitting, and are more prone to experience lower self-efficacy. Determining whether smoking cessation self-efficacy scores are invariant across these populations is crucial for future research and intervention strategies...
March 2017: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/28178770/interventions-to-improve-antibiotic-prescribing-practices-for-hospital-inpatients
#19
REVIEW
Peter Davey, Charis A Marwick, Claire L Scott, Esmita Charani, Kirsty McNeil, Erwin Brown, Ian M Gould, Craig R Ramsay, Susan Michie
BACKGROUND: Antibiotic resistance is a major public health problem. Infections caused by multidrug-resistant bacteria are associated with prolonged hospital stay and death compared with infections caused by susceptible bacteria. Appropriate antibiotic use in hospitals should ensure effective treatment of patients with infection and reduce unnecessary prescriptions. We updated this systematic review to evaluate the impact of interventions to improve antibiotic prescribing to hospital inpatients...
February 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28166548/nicotine-carcinogen-and-toxin-exposure-in-long-term-e-cigarette-and-nicotine-replacement-therapy-users-a-cross-sectional-study
#20
Lion Shahab, Maciej L Goniewicz, Benjamin C Blount, Jamie Brown, Ann McNeill, K Udeni Alwis, June Feng, Lanqing Wang, Robert West
Background: Given the rapid increase in the popularity of e-cigarettes and the paucity of associated longitudinal health-related data, the need to assess the potential risks of long-term use is essential. Objective: To compare exposure to nicotine, tobacco-related carcinogens, and toxins among smokers of combustible cigarettes only, former smokers with long-term e-cigarette use only, former smokers with long-term nicotine replacement therapy (NRT) use only, long-term dual users of both combustible cigarettes and e-cigarettes, and long-term users of both combustible cigarettes and NRT...
March 21, 2017: Annals of Internal Medicine
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