keyword
MENU ▼
Read by QxMD icon Read
search

undifferentiated arthritis

keyword
https://www.readbyqxmd.com/read/28663326/clinical-associations-of-the-positive-anti-ro52-without-ro60-autoantibodies-undifferentiated-connective-tissue-diseases
#1
Sai H K Murng, Moira Thomas
AIMS: Autoantibodies targeting Ro52 and Ro60 antigens are historically reported as anti SSA/Ro. In general anti SSA/Ro results are either anti Ro52+Ro60+ or anti Ro52-Ro60+ antibodies. Anti Ro52 without anti Ro60 (Ro52+ Ro60-) antibodies are often not reported routinely. This study intends to review the potential significance of these autoantibodies in the management of connective tissue diseases. METHOD: A retrospective survey of Ro52+Ro60- was carried out as part of the service evaluation of extractable nuclear antigen antibodies (ENA) reporting from the immunology laboratory, the NHS Greater Glasgow and Clyde (GGC), UK...
June 29, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28638684/the-new-acr-eular-criteria-for-rheumatoid-arthritis-can-identify-patients-with-same-disease-activity-but-less-damage-by-ultrasound
#2
Sibel Zehra Aydın, Concepcion Castillo-Gallego, Jackie Nam, Jane Freeston, Sarah Horton, Richard J Wakefield, Paul Emery
OBJECTIVE: We aimed to compare the ultrasound findings of patients fulfilling the 1987 ACR [OLD-rheumatoid arthritis (RA)] and the new ACR/EULAR (NEW-RA) classification criteria to examine the impact of the new criteria on disease characteristics, particularly disease duration. MATERIAL AND METHODS: A total of 2730 hands, wrists, elbows, knees, ankles, and foot joints of 105 consecutive patients with inflammatory arthritis, i.e., 82 patients fulfilling the RA criteria (60 patients, OLD-RA; 22 patients, NEW-RA alone) and 23 patients with undifferentiated arthritis, were scanned using ultrasound...
June 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28589388/-efficacy-and-safety-analysis-of-off-label-treatment-with-biologics-in-autoinflammatory-diseases-experiences-from-a%C3%A2-german-registry%C3%A2-graid2
#3
F Proft, M Fleck, C Fiehn, H Schulze-Koops, M Witt, T Dörner, J C Henes
OBJECTIVE: To evaluate the safety and efficacy of therapy with biologics in patients with autoinflammatory diseases (AIF) or macrophage activating syndrome (MAS) in a real-life setting in Germany. METHODS: The German Register of Autoimmune Diseases 2 (GRAID2) is a retrospective, non-interventional, multicenter registry collecting data from all patients with inflammatory rheumatic diseases refractory to conventional therapy and treated with initial off-label biologics between August 2006 and December 2013...
June 6, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28569568/performance-of-the-classification-criteria-in-patients-with-late-onset-axial-spondyloarthritis
#4
Louise T Bendahan, Natália P Machado, Jamille G Mendes, Thauana L Oliveira, Marcelo M Pinheiro
AIM: To evaluate the performance of four different classification criteria for spondyloarthritis (SpA) in patients with late-onset symptoms and to compare the clinical, laboratory and radiographic outcomes among the patients with symptoms before and after 45 years of age. PATIENTS AND METHODS: A total of 329 patients with SpA were enrolled in this prospective cohort. Patients with psoriatic arthritis, reactive arthritis, colitis associated arthritis and peripheral or undifferentiated SpA were excluded...
June 1, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28558734/the-effects-of-arthritis-gloves-on-people-with-rheumatoid-arthritis-or-inflammatory-arthritis-with-hand-pain-a-study-protocol-for-a-multi-centre-randomised-controlled-trial-the-a-gloves-trial
#5
Yeliz Prior, Chris Sutton, Sarah Cotterill, Jo Adams, Elizabeth Camacho, Nazina Arafin, Jill Firth, Terence O'Neill, Yvonne Hough, Wendy Jones, Alison Hammond
BACKGROUND: Arthritis gloves are regularly provided as part of the management of people with rheumatoid arthritis (RA) and undifferentiated (early) inflammatory arthritis (IA). Usually made of nylon and elastane (i.e. Lycra®), these arthritis gloves apply pressure with the aims of relieving hand pain, stiffness and improving hand function. However, a systematic review identified little evidence supporting their use. We therefore designed a trial to compare the effectiveness of the commonest type of arthritis glove provided in the United Kingdom (Isotoner gloves) (intervention) with placebo (control) gloves (i...
May 30, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28552544/lung-manifestations-in-the-rheumatic-diseases
#6
REVIEW
Tracy J Doyle, Paul F Dellaripa
Lung ailments in rheumatic diseases present unique challenges for diagnosis and management and are a source of significant morbidity and mortality for patients. Unlike the idiopathic interstitial pneumonias, patients with rheumatic diseases experience lung disease in the context of a systemic disease that may make it more difficult to recognize and that may present greater risks with treatment. Despite recent advances in our awareness of these diseases, there is still a significant lack of understanding of natural history to elucidate which patients will have disease that is progressive and thus warrants treatment...
May 25, 2017: Chest
https://www.readbyqxmd.com/read/28551592/heterogeneity-of-the-cytokinome-in-undifferentiated-arthritis-progressing-to-rheumatoid-arthritis-and-its-change-in-the-course-of-therapy-move-toward-personalized-medicine
#7
Edyta Brzustewicz, Izabella Bzoma, Agnieszka Daca, Maria Szarecka, Malgorzata Sochocka Bykowska, Jacek M Witkowski, Ewa Bryl
OBJECTIVES: To conduct a comprehensive analysis of cytokine concentrations in sera and mononuclear cell supernatants in order to examine inter- and intra-individual cytokine variations in undifferentiated arthritis progressing to rheumatoid arthritis and healthy control groups. METHODS: Patients with UA (undifferentiated arthritis) developing RA (rheumatoid arthritis) (UA→RA) (n=16) and healthy controls (n=16) were enrolled into the study. UA→RA patients were followed up for six months since the final RA diagnosis...
May 25, 2017: Cytokine
https://www.readbyqxmd.com/read/28539676/results-from-polish-spondyloarthritis-initiative-registry-polspi-methodology-and-data-from-the-first-year-of-observation
#8
Zofia Guła, Tacjana Barczyńska, Marek Brzosko, Jerzy Gąsowski, Sławomir Jeka, Katarzyna Jodłowska-Cicio, Beata Kwaśny-Krochin, Piotr Leszczyński, Łukasz Lubiński, Katarzyna Łosińska, Katarzyna Pawlak-Buś, Hanna Przepiera-Będzak, Włodzimierz Samborski, Małgorzata Schlabs, Maciej Siedlar, Dorota Sikorska, Jerzy Świerkot, Małgorzata Węgierska, Piotr Wiland, Mariusz Korkosz
OBJECTIVES: Report on one-year results from the Polish Spondyloarthritis Initiative registry (PolSPI), containing the cross-sectional analysis of clinical and imaging data as well as database methodology. MATERIAL AND METHODS: The PolSPI registry includes patients with axial (axSpA) and peripheral (perSpA) spondyloarthritis according to ASAS classification criteria, and/or patients with ankylosing spondylitis according to modified New York criteria, psoriatic arthritis according to CASPAR criteria, arthropathy in inflammatory bowel disease, reactive arthritis, juvenile spondyloarthritis or undifferentiated spondyloarthritis...
2017: Reumatologia
https://www.readbyqxmd.com/read/28521824/are-ankylosing-spondylitis-psoriatic-arthritis-and-undifferentiated-spondyloarthritis-associated-with-an-increased-risk-of-cardiovascular-events-a-prospective-nationwide-population-based-cohort-study
#9
Karin Bengtsson, Helena Forsblad-d'Elia, Elisabeth Lie, Eva Klingberg, Mats Dehlin, Sofia Exarchou, Ulf Lindström, Johan Askling, Lennart T H Jacobsson
BACKGROUND: To investigate the risk of first-time acute coronary syndrome (ACS), stroke and venous thromboembolism (VTE) in patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA) and undifferentiated spondyloarthritis (uSpA), compared to each other and to the general population (GP). METHODS: This is a prospective nationwide cohort study. Cohorts with AS (n = 6448), PsA (n = 16,063) and uSpA (n = 5190) patients and a GP (n = 266,435) cohort, were identified 2001-2009 in the Swedish National Patient and Population registers...
May 18, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28496443/higher-levels-of-secretory-iga-are-associated-with-low-disease-activity-index-in-patients-with-reactive-arthritis-and-undifferentiated-spondyloarthritis
#10
Fabián Salas-Cuestas, Wilson Bautista-Molano, Juan M Bello-Gualtero, Ivonne Arias, Diana Marcela Castillo, Lorena Chila-Moreno, Rafael Valle-Oñate, Daniel Herrera, Consuelo Romero-Sánchez
INTRODUCTION: Both reactive arthritis (ReA) and undifferentiated spondyloarthritis (uSpA) belong to the group of autoinflammatory diseases called spondyloarthritis (SpA). Hypotheses have been proposed about a relationship between the intestinal mucosa and inflammation of joint tissues. The role of immunoglobulin IgA or secretory immunoglobulin A (SIgA) in the inflammatory and/or clinical activity of patients with SpA remains poorly understood. OBJECTIVE: To evaluate the status of total IgA and SIgA, and the association among the levels of SIgA, IgA, IgA anti-Chlamydia trachomatis, and anti-Shigella spp...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28480094/validation-of-leiden-score-in-predicting-progression-of-rheumatoid-arthritis-in-undifferentiated-arthritis-in-indian-population
#11
K Ghosh, A Chatterjee, S Ghosh, S Chakraborty, P Chattopadhyay, A Bhattacharya, M Pal
BACKGROUND: Leiden Score, is a very useful tool for predicting future development of rheumatoid arthritis (RA), among undifferentiated arthritis (UA) patients. This score has been validated in various western studies but rarely among south east Asian patients. AIMS: To validate the Leiden early arthritis prediction rule in an Indian cohort of patients for predicting rheumatoid arthritis (RA) in undifferentiated arthritis (UA) patients and to formulate any simpler version of prediction score taking only clinical variables of original Leiden prediction rule...
July 2016: Annals of Medical and Health Sciences Research
https://www.readbyqxmd.com/read/28476103/intracranial-lesion-as-onset-symptom-in-a-patient-with-early-undifferentiated-connective-tissue-disease-a-case-report
#12
Ying Du, Chuan Li, Dai-di Zhao, Jia-Rui Lu, Wei Zhang, Zhu-Yi Li
BACKGROUND: Undifferentiated connective tissue disease (UCTD) is widely considered to be a distinct clinical entity, and now divided into two subgroups: stable UCTD and early UCTD. The most frequent onset symptoms of UCTD include arthralgias, arthritis, Raynaud's phenomenon, mucocutaneous involvement, and sicca symptoms. However, Neurologic involvement is rare, and intracranial lesion as onset symptom in a patient with early UCTD has not yet been reported. CASE PRESENTATION: A 51-year-old Chinese female experienced progressive left leg weakness for 14 days before hospitalizing in our department...
May 5, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28469936/ultrasound-detectable-grey-scale-synovitis-predicts-future-fulfilment-of-the-2010-acr-eular-ra-classification-criteria-in-patients-with-new-onset-undifferentiated-arthritis
#13
Sarah C Horton, Ai Lyn Tan, Richard J Wakefield, Jane E Freeston, Maya H Buch, Paul Emery
OBJECTIVE: To determine the clinical outcomes for patients with new-onset undifferentiated arthritis (UA), not fulfilling the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) rheumatoid arthritis (RA) classification criteria, and the clinical and imaging predictors of disease progression in these patients. METHODS: A prospective observational study was conducted in treatment-naïve UA patients. Baseline ultrasound involved semiquantitative assessment of grey scale (GS) synovitis and power Doppler activity (PD) at 26 joints...
2017: RMD Open
https://www.readbyqxmd.com/read/28466365/women-with-silicone-breast-implants-and-autoimmune-inflammatory-syndrome-induced-by-adjuvants-description-of-three-patients-and-a-critical-review-of-the-literature
#14
REVIEW
Slavica Pavlov-Dolijanovic, Nada Vujasinovic Stupar
Silicone has been widely used in the manufacture of medical implants. It is well tolerated in most cases. However, in this paper we report the cases of three women who developed autoimmune/inflammatory syndrome induced by adjuvants (ASIA syndrome), namely with silicone breast implants. The symptoms in these cases include arthralgia, arthritis, myalgia, sleep disturbances, the appearance of autoantibodies, miscarriage, Raynaud's phenomenon, and involvement of autoimmune diseases (scleroderma and undifferentiated connective tissue diseases)...
May 2, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28455435/cd40l-dependent-pathway-is-active-at-various-stages-of-rheumatoid-arthritis-disease-progression
#15
Yanxia Guo, Alice M Walsh, Ursula Fearon, Malcolm D Smith, Mihir D Wechalekar, Xuefeng Yin, Suzanne Cole, Carl Orr, Trudy McGarry, Mary Canavan, Stephan Kelly, Tai-An Lin, Xuejun Liu, Susanna M Proudman, Douglas J Veale, Costantino Pitzalis, Sunil Nagpal
The inflammatory CD40-CD40L pathway is implicated in various autoimmune diseases, but the activity status of this pathway in various stages of rheumatoid arthritis (RA) progression is unknown. In this study, we used gene signatures of CD40L stimulation derived from human immature dendritic cells and naive B cells to assess the expression of CD40-downstream genes in synovial tissues from anti-citrullinated protein Ab-positive arthralgia, undifferentiated arthritis (UA), early RA, and established RA cohorts in comparison with healthy donors...
April 28, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28446218/increased-galectin-3-may-serve-as-a-serologic-signature-of-pre-rheumatoid-arthritis-while-markers-of-synovitis-and-cartilage-do-not-differ-between-early-undifferentiated-arthritis-subsets
#16
Saida Farah Issa, Anne Duer, Mikkel Østergaard, Kim Hørslev-Petersen, Merete L Hetland, Michael Sejer Hansen, Kirsten Junker, Hanne M Lindegaard, Jakob M Møller, Peter Junker
BACKGROUND: Undifferentiated arthritis (UA) is a label applied to patients with joint complaints which cannot be classified according to current criteria, which implies a need for precision diagnostic technologies. We studied serum galectin-3, a proinflammatory mediator, and seromarkers of structural joint elements in patients with early, UA and their associations with disease profile and biochemical and imaging findings. METHODS: One hundred and eleven UA patients were followed-up for at least 12 months and reclassified according to appropriate criteria (TUDAR)...
April 26, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28390966/il-17-and-ifn-%C3%AE-producing-nk-and-%C3%AE-%C3%AE-t-cells-are-preferentially-expanded-in-synovial-fluid-of-patients-with-reactive-arthritis-and-undifferentiated-spondyloarthritis
#17
Abhra Chandra Chowdhury, Smriti Chaurasia, Shravan Kumar Mishra, Amita Aggarwal, Ramnath Misra
The IL-17/1L-23 axis is important in the pathogenesis of spondyloarthropathy. Innate cells produce IL-17 in addition to Th17 cells. We studied the frequencies of natural killer (NK) (total, CD56(bright), CD56(dim), perforin+ and granzyme+), NK-T, γδ-T, and IFN-γ+, IL-17+ NK and γδ-T cells in peripheral blood (PB) and synovial fluid (SF) of ReA/uSpA patients. PB from 45 patients and paired SF from 39 patients were studied, together with PB from 18 healthy controls (HC). The frequency of γδ-T cells was decreased (p<0...
April 6, 2017: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/28217975/brief-report-clinical-trials-aiming-to-prevent-rheumatoid-arthritis-cannot-detect-prevention-without-adequate-risk-stratification-a-trial-of-methotrexate-versus-placebo-in-undifferentiated-arthritis-as-an-example
#18
Leonie E Burgers, Cornelia F Allaart, Tom W J Huizinga, Annette H M van der Helm-van Mil
OBJECTIVE: Prevention of rheumatoid arthritis (RA) was the aim of several trials in undifferentiated arthritis (UA), with overall negative results. As preparatory work has revealed that only ∼30% of UA patients progress to having RA, we hypothesized that inclusion of patients without imminent RA could lead to false-negative results. We undertook this study to evaluate this hypothesis by reinvestigating the Probable Rheumatoid Arthritis: Methotrexate versus Placebo Treatment (PROMPT) trial (a 1-year course of methotrexate [MTX] versus placebo in UA) after excluding patients without a high risk of developing RA...
May 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28188938/multipotent-stem-cell-and-current-application
#19
REVIEW
Aligholi Sobhani, Neda Khanlarkhani, Maryam Baazm, Farzaneh Mohammadzadeh, Atefeh Najafi, Shayesteh Mehdinejadiani, Fereydoon Sargolzaei Aval
Stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. Stem cells can be classified into two main types based on their source of origin: Embryonic and Adult stem cells. Stem cells also classified based on the range of differentiation potentials into Totipotent, Pluripotent, Multipotent, and Unipotent. Multipotent stem cells have the ability to differentiate into all cell types within one particular lineage. There are plentiful advantages and usages for multipotent stem cells...
January 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28152001/does-non-adherence-to-dmards-influence-hospital-related-healthcare-costs-for-early-arthritis-in-the-first-year-of-treatment
#20
Annelieke Pasma, Charlotte Schenk, Reinier Timman, Adriaan van 't Spijker, Cathelijne Appels, Willemijn H van der Laan, Bart van den Bemt, Robert Goekoop, Johanna M W Hazes, Jan J V Busschbach
INTRODUCTION: Non-adherence to disease-modifying antirheumatic drugs (DMARDs) is suspected to relate to health care costs. In this study we investigated this relation in the first year of treatment. METHODS: In a multi-center cohort study with a one year follow up, non-adherence was continuously measured using electronic monitored medication jars. Non-adherence was defined as the number of days with a negative difference between expected and observed opening of the container...
2017: PloS One
keyword
keyword
110738
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"