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Mini Mental State

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https://www.readbyqxmd.com/read/28214402/relationship-between-chewing-ability-and-cognitive-impairment-in-the-rural-elderly
#1
Eun-Kyong Kim, Sung Kook Lee, Youn-Hee Choi, Makiko Tanaka, Kimiko Hirotsu, Hyeon Chang Kim, Hee-Kyung Lee, Yun-Sook Jung, Atsuo Amano
OBJECTIVE: Relationship between masticatory function and cognitive impairment had been suggested but still understudied. We investigated the association between chewing ability and cognitive impairment among the elderly living in a rural region. METHODS: A total of 295 elderly individuals aged ≥70 years in a rural city of Korea participated in a cross-sectional study. Trained nurses conducted interviews and assessed chewing ability using gum that changed color based on chewing performance...
February 11, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28212570/altered-amygdala-and-hippocampus-effective-connectivity-in-mild-cognitive-impairment-patients-with-depression-a-resting-state-functional-mr-imaging-study-with-granger-causality-analysis
#2
Li Juan Zheng, Gui Fen Yang, Xin Yuan Zhang, Yun Fei Wang, Ya Liu, Gang Zheng, Guang Ming Lu, Long Jiang Zhang, Ying Han
Neuroimaging studies have demonstrated that the major depression disorder would increase the risk of dementia in the older with amnestic cognitive impairment. We used granger causality analysis algorithm to explore the amygdala- and hippocampus-based directional connectivity patterns in 12 patients with major depression disorder and amnestic cognitive impairment (mean age: 69.5 ± 10.3 years), 13 amnestic cognitive impairment patients (mean age: 72.7 ± 8.5 years) and 14 healthy controls (mean age: 64.7 ± 7...
February 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28210220/mri-based-classification-models-in-prediction-of-mild-cognitive-impairment-and-dementia-in-late-life-depression
#3
Aleksandra K Lebedeva, Eric Westman, Tom Borza, Mona K Beyer, Knut Engedal, Dag Aarsland, Geir Selbaek, Asta K Haberg
Objective: Late-life depression (LLD) is associated with development of different types of dementia. Identification of LLD patients, who will develop cognitive decline, i.e., the early stage of dementia would help to implement interventions earlier. The purpose of this study was to assess whether structural brain magnetic resonance imaging (MRI) in LLD patients can predict mild cognitive impairment (MCI) or dementia 1 year prior to the diagnosis. Methods: LLD patients underwent brain MRI at baseline and repeated clinical assessment after 1-year...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28202477/vitamin-d-is-not-associated-with-incident-dementia-or-cognitive-impairment-an-18-y-follow-up-study-in-community-living-old-men
#4
Erika Olsson, Liisa Byberg, Brita Karlström, Tommy Cederholm, Håkan Melhus, Per Sjögren, Lena Kilander
Background: Vitamin D has been implicated as being important for maintaining cognitive function in old age. Results from longitudinal studies examining the association of vitamin D with incident dementia and cognitive impairment have been inconsistent.Objective: We investigated the relation between vitamin D, assessed in 3 different ways, and the risk of dementia.Design: We measured plasma 25-hydroxyvitamin D [25(OH)D] with the use of high-performance liquid chromatography-mass spectrometry, assessed dietary vitamin D intake with the use of 7-d dietary records, and created a vitamin D-synthesis genetic risk score (GRS) at baseline (1991-1995) in a cohort of 1182 Swedish men (mean age: 71 y)...
February 15, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28199971/association-and-interaction-effects-of-alzheimer-s-disease-associated-genes-and-lifestyle-on-cognitive-aging-in-older-adults-in-a-taiwanese-population
#5
Eugene Lin, Shih-Jen Tsai, Po-Hsiu Kuo, Yu-Li Liu, Albert C Yang, Chung-Feng Kao
Genome-wide association studies and meta-analyses implicated that increased risk of developing Alzheimer's diseases (AD) has been associated with the ABCA7, APOE, BIN1, CASS4, CD2AP, CD33, CELF1, CLU, CR1, DSG2, EPHA1, FERMT2, HLA-DRB1, HLA-DRB4, INPP5D, MEF2C, MS4A4A, MS4A4E, MS4A6E, NME8, PICALM, PLD3, PTK2B, RIN3, SLC24A4, SORL1, and ZCWPW1 genes. In this study, we assessed whether single nucleotide polymorphisms (SNPs) within these 27 AD-associatedgenes are linked with cognitive aging independently and/or through complex interactions in an older Taiwanese population...
February 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28197821/evaluation-of-glymphatic-system-activity-with-the-diffusion-mr-technique-diffusion-tensor-image-analysis-along-the-perivascular-space-dti-alps-in-alzheimer-s-disease-cases
#6
Toshiaki Taoka, Yoshitaka Masutani, Hisashi Kawai, Toshiki Nakane, Kiwamu Matsuoka, Fumihiko Yasuno, Toshifumi Kishimoto, Shinji Naganawa
PURPOSE: The activity of the glymphatic system is impaired in animal models of Alzheimer's disease (AD). We evaluated the activity of the human glymphatic system in cases of AD with a diffusion-based technique called diffusion tensor image analysis along the perivascular space (DTI-ALPS). MATERIALS AND METHODS: Diffusion tensor images were acquired to calculate diffusivities in the x, y, and z axes of the plane of the lateral ventricle body in 31 patients. We evaluated the diffusivity along the perivascular spaces as well as projection fibers and association fibers separately, to acquire an index for diffusivity along the perivascular space (ALPS-index) and correlated them with the mini mental state examinations (MMSE) score...
February 14, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28188962/impact-of-poor-sleep-quality-and-physical-inactivity-on-cognitive-function-in-community-dwelling-older-adults
#7
Sho Nakakubo, Hyuma Makizako, Takehiko Doi, Kota Tsutsumimoto, Sangyoon Lee, Sungchul Lee, Ryo Hotta, Seongryu Bae, Takao Suzuki, Hiroyuki Shimada
AIM: The purpose of the present study was to examine whether the combination of subjective sleep quality and physical activity is associated with cognitive performance among community-dwelling older adults. METHODS: Cross-sectional data on 5381 older adults who participated in part of the National Center for Geriatrics and Gerontology - Study of Geriatric Syndromes were analyzed. We assessed general cognitive impairment using the Mini-Mental State Examination, and also assessed story memory, attention, executive function and processing speed using the National Center for Geriatrics and Gerontology Functional Assessment Tool...
February 11, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28187171/anticholinergic-burden-and-cognitive-function-in-a-large-german-cohort-of-hospitalized-geriatric-patients
#8
Barbara Pfistermeister, Thomas Tümena, Karl-Günter Gaßmann, Renke Maas, Martin F Fromm
PURPOSE: Previous studies suggest an association between use of anticholinergic drugs in elderly patients and cognitive impairment. However, there are still limited data on the association of anticholinergic drug use and cognitive impairment as well as contribution of individual drugs to anticholinergic load using large, well-documented patient cohorts treated in geriatric units from Europe. METHODS: We investigated 797,440 prescriptions to 89,579 hospitalized patients treated in geriatric units within the GiB-DAT database...
2017: PloS One
https://www.readbyqxmd.com/read/28187153/what-matters-for-life-satisfaction-among-the-oldest-old-evidence-from-china
#9
Sor Tho Ng, Nai Peng Tey, M Niaz Asadullah
OBJECTIVE: The world population is aging rapidly and the well-being of older people is of great interest. Therefore, this study investigates the determinants of life satisfaction among the oldest-old (i.e. individuals aged 80 or over) in China. MATERIALS AND METHODS: We use the 2011/2012 Chinese Longitudinal Healthy Longevity Survey data (n = 6530) for this paper. Logistic regression is used to analyse the effects of socio-demographic, economic, health, instrumental activities of daily living, family and community factors on life satisfaction and depression among the oldest-old in China...
2017: PloS One
https://www.readbyqxmd.com/read/28186867/significant-improvement-in-cognition-in-mild-to-moderately-severe-dementia-cases-treated-with-transcranial-plus-intranasal-photobiomodulation-case-series-report
#10
Anita E Saltmarche, Margaret A Naeser, Kai Fai Ho, Michael R Hamblin, Lew Lim
OBJECTIVE: This study investigated whether patients with mild to moderately severe dementia or possible Alzheimer's disease (AD) with Mini-Mental State Exam (MMSE) Baseline scores of 10-24 would improve when treated with near-infrared photobiomodulation (PBM) therapy. BACKGROUND: Animal studies have presented the potential of PBM for AD. Dysregulation of the brain's default mode network (DMN) has been associated with AD, presenting the DMN as an identifiable target for PBM...
February 10, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28186314/psychopathological-profile-and-prevalence-of-dual-pathology-on-patients-with-alcoholic-dependence-undergoing-outpatient-treatment
#11
Miguel A García-Carretero, José P Novalbos-Ruiz, María Robles-Martínez, María A Jordán-Quintero, Cristina O'Ferrall-González
AIMS: Assess the prevalence of dual pathology in patients with alcohol dependence and describe the psychopathological profile of mental disorders, impulsiveness, ADHD presence and craving. METHOD: It is a cross-sectional study about dual pathology, carried out on 102 patients undergoing outpatient treatment. The presence of dual pathology is established by means of the MINI-5 interview and the MCMI-III test; DSM-IV being used as the alcohol abuse criteria. Impulsiveness, ADHD presence, craving and quality of life were measured through SIS, ASRSv1, MACS and SF-36...
January 2017: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/28182163/which-is-preferable-for-orthostatic-hypotension-diagnosis-in-older-adults-active-standing-test-or-head-up-tilt-table-test
#12
Ali Ekrem Aydin, Pinar Soysal, Ahmet Turan Isik
BACKGROUND: Correct evaluation of orthostatic hypotension (OH) is crucial in geriatric practice, since OH is associated with mortality and morbidity. The study aimed to determine the most appropriate method for measuring blood pressure in transition from supine to upright position in order to diagnose OH in older adults. METHODS: Active standing test (AST) and head-up tilt table (HUT) test as well as comprehensive geriatric assessment (CGA), including mini-mental state examination or the cognitive state test, mini-nutritional assessment, basic and instrumental activities of daily living, and Tinetti performance-oriented mobility assessment indexes, were performed in 290 geriatric patients...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28182146/multiple-diabetic-complications-as-well-as-impaired-physical-and-mental-function-are-associated-with-declining-balance-function-in-older-persons-with-diabetes-mellitus
#13
Xiufang Hong, Xujiao Chen, Jiaojiao Chu, Shanshan Shen, Qichen Chai, Gaobo Lou, Lingyan Chen
OBJECTIVE: To investigate whether there is a difference in balance function between older persons with and without diabetes mellitus (DM), and to identify whether mediating factors, such as diabetic complications, Instrumental Activities of Daily Living (IADL) score, Mini-Mental State Examination (MMSE) score, as well as hemoglobin A1c (HbA1c), fasting plasma glucose (FPG), serum total cholesterol (TC), triglycerides (TG), and low-density lipoprotein (LDL), are associated with balance function in older persons with DM...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28176504/morphological-and-microstructural-changes-of-the-hippocampus-in-early-mci-a-study-utilizing-the-alzheimer-s-disease-neuroimaging-initiative-database
#14
Peter Lee, Hojin Ryoo, Jinah Park, Yong Jeong
BACKGROUND AND PURPOSE: With the aim of facilitating the early detection of Alzheimer's disease, the Alzheimer's Disease Neuroimaging Initiative proposed two stages based on the memory performance: early mild cognitive impairment (EMCI) and late mild cognitive impairment (LMCI). The current study was designed to investigate structural differences in terms of surface atrophy and microstructural changes of the hippocampus in EMCI and LMCI. METHODS: Hippocampal shape modeling based on progressive template surface deformation was performed on T1-weighted MRI images obtained from 20 cognitive normal (CN) subjects, 17 EMCI patients, and 20 LMCI patients...
January 25, 2017: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/28176306/cognitive-differences-between-men-and-women-who-fracture-their-hip-and-impact-on-six-month-survival
#15
Ann L Gruber-Baldini, Mina Hosseini, Denise Orwig, Lynn Grattan, Nancy Chiles Shaffer, Marc Hochberg, Jay Magaziner
OBJECTIVES: There is limited research in cognition and its relationship to mortality after hip fracture among men compared to women. Therefore, the goals of this study were to: (1) compare men and women who fractured their hip on cognition after hospital discharge, and (2) examine the impact of cognition on the differential risk of 6-month mortality between men and women post fracture. DESIGN: Prospective cohort study. SETTING: Eight hospitals in Baltimore, Maryland...
February 8, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28174449/effect-of-sensorimotor-stimulation-on-chronic-stroke-patients-upper-extremity-function-a-preliminary-study
#16
Eun-Ji Go, Sang-Heon Lee
[Purpose] The aim of this study was to investigate the effect of an intensive sensorimotor stimulation program on the motor function of chronic hemiparetic patients. [Subjects and Methods] The subjects were three chronic stroke patients whose sensory function was intact, who had Mini-Mental State Examination - Korean version scores of more than 26, and manual muscle test scores of more than fair for affected shoulder and elbow. The research design was an A-B single subject experimental design. The intervention consisted of 4 baselines phase sessions, and 12 sensorimotor stimulation phase sessions...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28170114/validation-of-the-chinese-version-of-addenbrooke-s-cognitive-examination-iii-for-diagnosing-dementia
#17
Bian-Rong Wang, Zhou Ou, Xiao-Hua Gu, Cun-Sheng Wei, Jun Xu, Jian-Quan Shi
OBJECTIVE: The aim of this study was to validate the reliability of the Chinese version of Addenbrooke's Cognitive Examination III (ACE-III) for detecting dementia. Furthermore, the present study compares the diagnostic accuracy of ACE-III with that of mini-mental state examination (MMSE). METHODS: One hundred seventy-seven patients with dementia and 180 healthy controls were included in the study. RESULTS: The reliability of ACE-III was very good (α-coefficient = 0...
February 7, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28165615/brain-mri-markers-associate-differentially-with-cognitive-versus-functional-decline-leading-to-dementia
#18
Vincentius J A Verlinden, Jos N van der Geest, Albert Hofman, Wiro J Niessen, Aad van der Lugt, Meike W Vernooij, M Arfan Ikram
BACKGROUND: Brain MRI-markers are risk factors of dementia and decline in cognition and daily functioning. It is unknown to what extent the associations of brain MRI-markers with cognition and daily functioning are part of the pathway leading to dementia. We aimed to investigate associations of brain MRI-markers with change in cognition and daily functioning during 15 years of follow-up, including their relation to dementia. DESIGN, SETTING, AND PARTICIPANTS: Four hundred and sixty three stroke-free and non-demented participants from the population-based Rotterdam Study that underwent brain-MRI, yielding brain volumetrics, between 1995 and 1996...
February 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28161090/repetitive-transcranial-magnetic-stimulation-combined-with-cognitive-training-for-the-treatment-of-alzheimer-s-disease
#19
Jean-Paul Nguyen, Alcira Suarez, Gilles Kemoun, Michel Meignier, Estelle Le Saout, Philippe Damier, Julien Nizard, Jean-Pascal Lefaucheur
OBJECTIVE: To assess the efficacy of a combination of cognitive training (COG) and repetitive transcranial magnetic stimulation (rTMS), on cognitive performance, locomotor activity, apathy, caregiver burden and dependence of patients with Alzheimer's disease (AD). METHODS: A combination of COG and rTMS was performed in 10 patients with AD (NeuroAD procedure) for a period of 5weeks (one session per day, 5days a week), without maintenance sessions. Patients were evaluated at the end of the treatment (D45) and 6months later (M6) by the Mini Mental State Examination (MMSE), the Alzheimer disease assessment scale - cognitive subscale (ADAS-Cog), various neuropsychological tests and clinical scores specific for locomotor activity, apathy, caregiver burden, and dependence, recorded before the study (baseline)...
February 1, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28159845/prevalence-and-determinants-of-undetected-dementia-in-the-community-a-systematic-literature-review-and-a-meta-analysis
#20
Linda Lang, Angela Clifford, Li Wei, Dongmei Zhang, Daryl Leung, Glenda Augustine, Isaac M Danat, Weiju Zhou, John R Copeland, Kaarin J Anstey, Ruoling Chen
OBJECTIVES: Detection of dementia is essential for improving the lives of patients but the extent of underdetection worldwide and its causes are not known. This study aimed to quantify the prevalence of undetected dementia and to examine its correlates. METHODS/SETTING/PARTICIPANTS: A systematic search was conducted until October 2016 for studies reporting the proportion of undetected dementia and/or its determinants in either the community or in residential care settings worldwide...
February 3, 2017: BMJ Open
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