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Mini Mental State

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https://www.readbyqxmd.com/read/29352127/structural-covariance-of-gray-matter-volume-in-hiv-vertically-infected-adolescents
#1
Jielan Li, Lei Gao, Zhi Wen, Jing Zhang, Panying Wang, Ning Tu, Hao Lei, Fuchun Lin, Xi'en Gui, Guangyao Wu
Human immunodeficiency virus (HIV) infection significantly affect neurodevelopmental and behavioral outcomes. We investigated whether alterations of gray matter organization and structural covariance networks with vertical HIV infection adolescents exist, by using the GAT toolbox. MRI data were analysed from 25 HIV vertically infected adolescents and 33 HIV-exposed-uninfected control participants. The gray matter volume (GMV) was calculated, and structural brain networks were reconstructed from gray matter co-variance...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29348624/soy-food-and-isoflavone-intake-reduces-the-risk-of-cognitive-impairment-in-elderly-japanese-women
#2
Mariko Nakamoto, Rei Otsuka, Yukiko Nishita, Chikako Tange, Makiko Tomida, Yuki Kato, Tomoko Imai, Tohru Sakai, Fujiko Ando, Hiroshi Shimokata
Data were derived from the National Institute for Longevity Sciences-Longitudinal Study of Aging. Subjects comprised 403 men and 373 women aged 60-81 years at baseline who participated in the follow-up study at least once. Bean, soy product and soy isoflavone intake was assessed using a 3-day dietary record at baseline. Cognitive function was assessed by the Mini-Mental State Examination (MMSE). MMSE scores of ≤23 were used to define cognitive impairment. The relationship between bean, soy product and soy isoflavone intake and cognitive impairment was assessed using a generalized estimating equation...
January 18, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29340614/association-of-polygenic-risk-score-with-cognitive-decline-and-motor-progression-in-parkinson-disease
#3
Kimberly C Paul, Jessica Schulz, Jeff M Bronstein, Christina M Lill, Beate R Ritz
Importance: Genetic factors have a well-known influence on Parkinson disease (PD) susceptibility. The largest genome-wide association study (GWAS) identified 26 independent single-nucleotide polymorphisms (SNPs) associated with PD risk. Among patients, the course and severity of symptom progression is variable, and little is known about the potential association of genetic factors with phenotypic variance. Objective: To assess whether GWAS-identified PD risk SNPs also have a cumulative association with the progression of cognitive and motor symptoms in patients with PD...
January 16, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29338817/correlation-of-stress-hyperglycemia-after-ischemic-stroke-with-early-vascular-cognitive-impairment
#4
Yi Dong Zhou, Huai Wu Yuan, Ren Jie Ji, Ben Yan Luo
Objective To investigate the influence and forecast value of stress hyperglycemia on the early vascular cognitive impairment (VCI) in stroke patients.Methods Totally 422 patients with acute non-diabetic stroke were divided into three groups according to the fasting plasma glucose level:the euglycemia group (<6.1 mmol/L),the mild stress hyperglycemia group (6.1-7.0 mmol/L),and the severe stress hyperglycemia group (≥7.0 mmol/L).Mini-mental state examination,Alzheimer's disease rating scale cognitive subscale,and clinical dementia rating scale were used to evaluate early cognition in post-stroke patients,and patients were divided into three groups accordingly:normal cognitive function group,mild VCI group,and vascular dementia group...
December 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29338743/the-prospective-and-concurrent-effect-of-exercise-on-health-related-quality-of-life-in-older-adults-over-a-3%C3%A2-year-period
#5
Helen-Maria Vasiliadis, Mathieu F Bélanger
BACKGROUND: It is not clear whether socioeconomic status influences health outcomes among older adults through its effect on physical activity. The aim of this study was to assess the effect of sex and neighborhood socio-economic status on the change in health related quality of life (HR-QOL) as a function of physical activity over a three-year period. METHODS: This cohort study included French-speaking community-dwelling older adults recruited in primary care practices in the province of Quebec and participating in the 'Étude sur la Santé des Ainés' (ESA)-Services study on the health of the elderly...
January 16, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29336840/heterozygous-tyrobp-deletion-ploslfin-is-not-a-strong-risk-factor-for-cognitive-impairment
#6
Karri Kaivola, Lilja Jansson, Elmo Saarentaus, Anna Kiviharju, Ville Rantalainen, Johan G Eriksson, Timo E Strandberg, Tuomo Polvikoski, Liisa Myllykangas, Pentti J Tienari
Biallelic loss-of-function mutations in TYROBP and TREM2 cause a rare disease that resembles early-onset frontotemporal dementia with bone lesions called polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Some PLOSL-causing variants in TREM2 have also been associated with Alzheimer's disease when heterozygous. Here, we studied the PLOSLFINTYROBP deletion that covers 4 of the gene's 5 exons. We genotyped 3220 older Finns (mean age 79, range 58-104) and found 11 deletion carriers (mean age 78, range 60-94)...
December 18, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/29336168/dementia-in-eastern-mediterranean-countries-a-systematic-review
#7
Sara Mahmoud Yaghmour, Ruth Bartlett, Tula Brannelly
Globally, there is an increase in the older population, whose lives are affected by local cultural norms. In Eastern Mediterranean countries, dementia is conventionally hidden from view with few dedicated services or recognition for diagnosis. The aim of this systematic review is to explore the limited literature on dementia and cognitive impairment among older people in Eastern Mediterranean countries to present an evaluation of current practices and to consolidate knowledge for future planning. Thirty-three studies were identified for inclusion in the review, and four themes were apparent...
January 1, 2018: Dementia
https://www.readbyqxmd.com/read/29335033/should-capacity-assessments-be-performed-routinely-prior-to-discussing-advance-care-planning-with-older-people
#8
Oleg Kiriaev, Emme Chacko, J D Jurgens, Meagan Ramages, Phillipa Malpas, Gary Cheung
BACKGROUND: People with dementia receive worse end of life care compared to those with cancer. Barriers to undertaking advanced care planning (ACP) in people with dementia include the uncertainty about their capacity to engage in such discussions. The primary aim of this study was to compare the Advance Care Planning-Capacity Assessment Vignette tool (ACP-CAV) with a semi-structured interview adapted from the MacArthur Competence Assessment Tool-Treatment (MacCAT-T). The secondary aim was to identify demographic and cognitive functioning variables that may predict whether a person has capacity to discuss ACP...
January 16, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29334906/rationale-and-design-of-the-carolina%C3%A2-cognition-substudy-a-randomised-controlled-trial-on-cognitive-outcomes-of-linagliptin-versus-glimepiride-in-patients-with-type-2-diabetes-mellitus
#9
Geert Jan Biessels, Jolien Janssen, Esther van den Berg, Bernard Zinman, Mark A Espeland, Michaela Mattheus, Odd Erik Johansen
BACKGROUND: Type 2 diabetes mellitus is associated with cognitive dysfunction and an increased risk of dementia. Linagliptin is a glucose-lowering agent of the dipeptidyl peptidase-IV (DPP-IV) inhibitor class that is of particular interest for the prevention of accelerated cognitive decline, because it may potentially benefit the brain through pleiotropic effects, beyond glucose lowering. This paper presents the design of a study that aims to establish if linagliptin is superior to the sulfonylurea glimepiride in the prevention of accelerated cognitive decline in patients with type 2 diabetes mellitus...
January 15, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29334234/is-there-an-association-between-severity-of-illness-and-psychiatric-symptoms-in-patients-with-chronic-renal-failure
#10
D Guenzani, M Buoli, G S Carnevali, M Serati, P Messa, S Vettoretti
Chronic renal failure (CRF) is a frequent condition in elderly subjects, and it is associated with psychiatric comorbidity, especially depressive symptoms. Purpose of the present research was to compare patients with different severity of chronic kidney disease (CKD) in terms of psychiatric symptoms. One hundred CKD subjects were randomly selected among those attending the Department of Nephrology, University of Milan. The patients were evaluated through the following rating scales: Mini-Mental State Examination (MMSE), Beck Depression Inventory (BDI), Symptom Checklist (SCL-90), Kidney Disease Quality of Life- Short Form (KDQOL-SF) and Cumulative Illness Rating Scale (CIRS)...
January 15, 2018: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/29332926/differentiating-between-alzheimer-disease-patients-and-controls-with-phase-difference-enhanced-imaging-at-3t-a-feasibility-study
#11
Machiko Tateishi, Mika Kitajima, Toshinori Hirai, Tetsuya Yoneda, Mamoru Hashimoto, Nan Kurehana, Hiroyuki Uetani, Ryuji Fukuhara, Minako Azuma, Yasuyuki Yamashita
PURPOSE: To test the feasibility of the phase difference enhanced (PADRE) imaging for differentiation between Alzheimer disease (AD) patients and control subjects on 3T MR imaging. MATERIALS AND METHODS: Fifteen patients with AD and 10 age-matched control subjects underwent two-dimensional fast field echo imaging to obtain PADRE images on a 3T MR scanner. A double Gaussian distribution model was used to determine the threshold phase value for differentiation between the physiologic and non-physiologic iron in the cerebral cortices, and PADRE images were processed with the threshold...
January 15, 2018: Magnetic Resonance in Medical Sciences: MRMS
https://www.readbyqxmd.com/read/29329723/prolonged-grief-and-cognitive-decline-a-prospective-population-based-study-in-middle-aged-and-older-persons
#12
Heidi C Saavedra Pérez, M Arfan Ikram, Nese Direk, Henning Tiemeier
OBJECTIVE: Bereavement can result in unresolved and prolonged grief, often termed prolonged grief disorder (PGD). The impact of PGD on cognitive functioning is poorly understood. The aim of the study was to compare the cognitive decline, assessed by repeated measures of different cognition domains, between persons with normal and PGD and a non-grieving reference population in a 7-year follow-up study. METHODS: The study sample comprised 3126 non-demented persons, mean age: 64 years, of the Rotterdam Study...
December 12, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29327173/personality-traits-patient-centered-health-status-and-prognosis-of-brain-tumor-patients
#13
Adomas Bunevicius
Personality traits can be related to prognosis of cancer patients. The study aimed to evaluate the association of big-five personality dimensions with emotional and cognitive health status, and prognosis of brain tumor patients. A total of 178 patients admitted for brain tumor surgery were evaluated for personality traits (Tem item Personality Inventory), depressive/anxiety symptoms (Hospital Anxiety and Depression Scale or HADS) and cognitive functioning (Mini Mental State Examination or MMSE) on admission...
January 11, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29323524/work-disability-in-soldiers-with-posttraumatic-stress-disorder-posttraumatic-embitterment-disorder-and-not-event-related-common-mental-disorders
#14
Beate Muschalla, Heinrich Rau, Gerd Dieter Willmund, Christine Knaevelsrud
OBJECTIVE: Posttraumatic mental disorders may occur with different affect qualities. Best known is posttraumatic stress disorder (PTSD), a conditioned anxiety reaction with intrusions. Another event-related mental disorder is posttraumatic embitterment (PTED), characterized by affect of embitterment and thoughts of revenge, occurring after an event deeply hurting basic beliefs. Knowing about associated disability is important for treatment and sociomedical decisions. This is the first study to explore work-disability in patients with PTSD, PTED, and not-event-related common mental disorder (CMD)...
January 2018: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29322488/difficulties-with-fine-motor-skills-and-cognitive-impairment-in-an-elderly-population-the-progetto-veneto-anziani
#15
Chiara Curreri, Caterina Trevisan, Pamela Carrer, Silvia Facchini, Valter Giantin, Stefania Maggi, Marianna Noale, Marina De Rui, Egle Perissinotto, Sabina Zambon, Gaetano Crepaldi, Enzo Manzato, Giuseppe Sergi
OBJECTIVES: To investigate dysfunction in fine motor skills in a cohort of older Italian adults, identifying their prevalence and usefulness as indicators and predictors of cognitive impairment. DESIGN: Population-based longitudinal study with mean follow-up of 4.4 years. SETTING: Community. PARTICIPANTS: Older men and women enrolled in the Progetto Veneto Anziani (Pro.V.A.) (N = 2,361); 1,243 subjects who were cognitively intact at baseline were selected for longitudinal analyses...
January 11, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29322314/cognitive-impairment-is-associated-with-elevated-serum-homocysteine-levels-among-older-adults
#16
Sunghee Kim, Bo Youl Choi, Jung Hyun Nam, Mi Kyung Kim, Dong Hoon Oh, Yoon Jung Yang
PURPOSE: The aim of this study was to examine the associations between the risk of cognitive impairment and the serum levels of folate, vitamin B12, and homocysteine (Hcy). METHODS: Subjects were persons aged 60-79 years who participated in the Yangpyeong Cohort study between 2011 and 2012. Cognitive impairment and normal subjects consisted of 100 pairs of old adults matched by age, sex, and education levels. Cognitive function was evaluated with the Korean version of the Mini-Mental State Examination for Dementia Screening (MMSE-DS)...
January 10, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29319499/similar-treatment-outcomes-with-ginkgo-biloba-extract-egb-761-and-donepezil-in-alzheimer-s-dementia-in-very-old-age-a-retrospective-observational-study
#17
Michael Rapp, Martin Burkart, Thomas Kohlmann, Jens Bohlken
OBJECTIVE: To provide pilot data for the safety and efficacy of EGb 761 in the oldest-old patients (aged 80 or older). MATERIALS AND METHODS: In a retrospective analysis, we compared treatment outcomes with EGb 761 or donepezil over 12 months in 189 patients aged 80 years or older suffering from Alzheimer's disease (AD). RESULTS: Over 12 months, there was no significant difference in cognitive decline, measured with the mini-mental state examination (MMSE) score, between donepezil and EGb 761 (p = 0...
January 10, 2018: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29318859/-xingnao-kaiqiao-acupuncture-acupuncture-technique-for-restoring-consciousness-combined-with-hyperbaric-oxygen-in-patients-with-hypoxic-ischemic-encephalopathy-clinical-observation-and-its-influence-on-blood-rheology
#18
Sheng-Yu Zhang, Shao-Bing Liu, Hong-Wu Xie, Yi-Min Chen, Kang-Lin Liao, Yong Xiang, Dun Pan
OBJECTIVE: To observe the effect of "Xingnao Kaiqiao" acupuncture(acupuncture technique for restoring consciousness) combined with hyperbaric oxygen in patients with hypoxic ischemic encephalopathy and assess its influence on blood rheology. METHODS: Forty patients with hypoxic ischemic encephalopathy were randomly divided into treatment group and control group with 20 cases in each group. The treatment group received "Xingnao Kaiqiao" acupuncture combined with hyperbaric oxygen, and the control group received hyperbaric oxygen only...
December 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29318089/falls-cognitive-function-and-balance-profiles-of-singapore-community-dwelling-elderly-individuals-key-risk-factors
#19
Mei Teng Woo, Keith Davids, Jarmo Liukkonen, Jia Yi Chow, Timo Jaakkola
Objective: This study compared occurrence of falls, cognitive function, and balance profiles across participants in elderly age categories, investigating associations between the 3 aspects in a sample of Singapore's elderly population. Method: Community-dwelling elderly individuals (N = 385) were randomly recruited and grouped into "young-old (65-74 years)," "medium-old (75-84 years)," and "oldest-old (above 85 years)" groups. The Fallproof Health and Activity questionnaire, adapted Mini-Mental State Examination (MMSE), and Berg Balance Scale (BBS) tests were used to survey information related to falls, cognition, and balance profiles...
December 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/29317809/best-strategies-to-recruit-and-enroll-elderly-blacks-into-clinical-and-biomedical-research
#20
Lennox A Graham, Julius Ngwa, Oyonumo Ntekim, Oludolapo Ogunlana, Saba Wolday, Steven Johnson, Megan Johnson, Chimene Castor, Thomas V Fungwe, Thomas O Obisesan
Background: Historically, Blacks have been disproportionately underrepresented in clinical trials. Outcomes associated with low Blacks' participation in research include poor understanding of the predictors and treatment of the disease, increasing health disparities, poor health equity, and suboptimal wellness of the nation as a whole. To address this gap in research participation, we analyzed our recruitment data to identify the most effective strategies for enrolling older Blacks in clinical trials...
2018: Clinical Interventions in Aging
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