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effect size d AND anesthesia

Jonatan Myrup Staalsø, Kim Zillo Rokamp, Niels D Olesen, Lars Lonn, Niels H Secher, Niels V Olsen, Teit Mantoni, Ulf Helgstrand, Henning B Nielsen
BACKGROUND: Gly16arg polymorphism of the adrenergic β2-receptor is associated with the elevated cardiac output (Q) in healthy gly16-homozygotic subjects. We questioned whether this polymorphism also affects Q and regional cerebral oxygen saturation (SCO2) during anesthesia in vascular surgical patients. METHODS: One hundred sixty-eight patients (age 71 ± 6 years) admitted for elective surgery were included. Cardiovascular variables were determined before and during anesthesia by intravascular pulse contour analysis (Nexfin) and SCO2 by cerebral oximetry (INVOS 5100C)...
September 13, 2016: Anesthesia and Analgesia
Stephanie N Moore, Gregory D Hawley, Emily N Smith, Nicholas A Mignemi, Rivka C Ihejirika, Masato Yuasa, Justin M M Cates, Xulei Liu, Jonathan G Schoenecker
INTRODUCTION: Soft tissue calcification, including both dystrophic calcification and heterotopic ossification, may occur following injury. These lesions have variable fates as they are either resorbed or persist. Persistent soft tissue calcification may result in chronic inflammation and/or loss of function of that soft tissue. The molecular mechanisms that result in the development and maturation of calcifications are uncertain. As a result, directed therapies that prevent or resorb soft tissue calcifications remain largely unsuccessful...
2016: PloS One
Usha Shukla, Tallamraju Prabhakar, Kiran Malhotra, Dheeraj Srivastava
BACKGROUND AND AIMS: Trials are being carried out to identify an adjuvant to intrathecal bupivacaine that preferably potentiates postoperative analgesia. This prospective, randomized, double-blind study was aimed to compare the onset and duration of sensory and motor block, postoperative analgesia and adverse effects of dexmedetomidine or midazolam given with 0.5% hyperbaric bupivacaine for spinal anesthesia. MATERIAL AND METHODS: A total of 80 patients, scheduled for vaginal hysterectomies, were randomly allocated to Group D (n = 40) to receive intrathecally 3...
April 2016: Journal of Anaesthesiology, Clinical Pharmacology
Arimatias Raitio, Rosie Cresner, Richard Smith, Matthew O Jones, Paul D Losty
AIM OF THE STUDY: To assess the safety and effectiveness of fluoroscopic balloon dilatation (FBD) in children with esophageal anastomotic stricture after surgical repair of esophageal atresia. METHODS: All patients undergoing surgery for esophageal atresia and requiring dilatation(s) during a consecutive 15-year period [April 2000-September 2014] were analyzed. Dilatations were performed as day case procedures under general anesthesia using a radial force generating balloon device (Boston Scientific Corporation) by surgeons...
September 2016: Journal of Pediatric Surgery
Alen Mathew, Anish N G Sharma, P Ganapathi, P Shankaranarayana, M Nazim, D S Aiyappa
AIMS: The present study is undertaken to compare the hemodynamic effects using vecuronium versus rocuronium for maintenance in patients undergoing general surgical procedures. SETTINGS AND DESIGN: It is a prospective, randomized, and cohort study. SUBJECTS AND METHODS: 100 patients were randomly divided into two groups. All patients were induced with 5 mg/kg of thiopentone sodium, and intubation conditions were achieved with 1.5 mg/kg of suxamethonium, using a well-lubricated cuffed endotracheal tube of appropriate size...
January 2016: Anesthesia, Essays and Researches
Constance Silbernagel, Pamela Yochem
Immersion anesthetics are used in hatchery settings by veterinarians, field biologists, and laboratory researchers to aid in handling finfish for medical procedures, research purposes, and moderating perceived stress responses. The only Food and Drug Administration- (FDA) approved anesthetic for food fish, tricaine methanesulfonate, requires a 21-d withdrawal period prior to harvest. Ten percent eugenol (AQUI-S® 20E) has been gaining momentum for FDA approval because of its 0-d withdrawal time if fish are not of harvestable size within 72 h of exposure...
April 2016: Journal of Wildlife Diseases
Paul D Metzger, Brian Barlow, Dominic Leonardelli, William Peace, Daniel J Solomon, Matthew T Provencher
BACKGROUND: The optimal treatment of Hill-Sachs injuries is difficult to determine and is potentiated by the finding that a Hill-Sachs injury becomes more important in the setting of glenoid bone loss, making engagement of the humeral head on the glenoid inherently easier. The "glenoid track" concept was developed to biomechanically quantify the effects of a combined glenoid and humeral head bony defects on instability. PURPOSE: To clinically evaluate humeral head engagement on the glenoid by utilizing glenoid track measurements of both humeral head and glenoid bone loss...
July 2013: Orthopaedic Journal of Sports Medicine
Daniel R Reissmann, Georgios Poulopoulos, Justin Durham
OBJECTIVE: To assess how patients actually perceive implant placement, to evaluate whether patients' perceived burdens are related to specific stages during implant placement, and to compare patients' perceptions during implant placement with other surgical procedures. METHODS: A sample of 287 patients was consecutively recruited. Only patients with implantations (n=45), surgical tooth removal (n=147), or apicectomies (n=95) were included. Patients' perceptions during oral surgery and implantation were assessed using the Burdens in Oral Surgery Questionnaire (BiOS-Q)...
December 2015: Journal of Dentistry
Yun Kuang, Ran-Ran Zhang, Qi Pei, Hong-Yi Tan, Cheng-Xian Guo, Jie Huang, Yu-Xia Xiang, Wen Ouyang, Kai-Ming Duan, Sai-Ying Wang, Guo-Ping Yang
OBJECTIVE: The application of dexmedetomidine in patient sedation is generally accepted, though its clinical application is limited because of the lack of information detailing the specific properties among diverse populations of patients. The aim of this study was to compare the pharmacokinetic and pharmacodynamic characteristics of dexmedetomidine between elderly and young patients during spinal anesthesia. METHODS: 34 subjects (elderly group: n = 15; young group: n = 19) with spinal anesthesia were enrolled in the present study following the inclusion/exclusion criteria detailed below...
December 2015: International Journal of Clinical Pharmacology and Therapeutics
A I Nejmark, B A Nejmark, M A Tachalov, D D Arzamascev, D V Torbik
The study included 59 patients with benign prostatic hyperplasia (BPH) and high risk of anesthesia who underwent superselective embolization of prostatic arteries. The examination included a survey on the International Prostate Symptom Score (IPSS), assessment of quality of life (QoL), estimation of prostate and node size with transrectal ultrasound, determination of prostate-specific antigen level; in doubtful cases a needle prostate biopsy was performed. To analyze the quality of urination uroflowmetry was conducted...
March 2015: Urologii︠a︡
Rebecca Y Klinger, Christopher A Thunberg, William D White, Manuel Fontes, Nathan H Waldron, Jonathan P Piccini, G Chad Hughes, Mihai V Podgoreanu, Mark Stafford-Smith, Mark F Newman, Joseph P Mathew
BACKGROUND: Hypomagnesemia has been associated with an increased risk of postoperative atrial fibrillation (POAF). Although previous studies have suggested a beneficial effect of magnesium (Mg) therapy, almost all of these are limited by small sample size and relatively low Mg dose. We hypothesized that high-dose Mg decreases the occurrence of new-onset POAF, and we tested this hypothesis by using data from a prospective trial that assessed the effect of Mg on cognitive outcomes in patients undergoing cardiac surgery...
October 2015: Anesthesia and Analgesia
Thierry de Baere, Lambros Tselikas, David Woodrum, Fereidoun Abtin, Peter Littrup, Frederic Deschamps, Robert Suh, Hussein D Aoun, Matthew Callstrom
INTRODUCTION: To assess the feasibility, safety and local tumor control of cryoablation for treatment of pulmonary metastases. MATERIALS AND METHODS: This Health Insurance Portability and Accountability Act (HIPAA) compliant, IRB-approved, multicenter, prospective, single arm study included 40 patients with 60 lung metastases treated during 48 cryoablation sessions, with currently a minimum of 12 months of follow-up. Patients were enrolled according to the following key inclusion criteria: 1 to 5 metastases from extrapulmonary cancers, with a maximal diameter of 3...
October 2015: Journal of Thoracic Oncology
Yang Wang, Hong-Li Kan, Hong Sun, Dong-Xin Wang, Huai-Wu Wang, Ji-Xin Liu
The aim of the present study was to investigate the feasibility of interventional magnetic resonance imaging (MRI)-guided and monitored argon-helium cryoablation for the treatment of brain tumors in rabbits. In addition, the present study evaluated the associations between imaging and pathology, the therapeutic effects and the effects on the surrounding normal tissues. A total of 14 rabbits were equally divided into groups C and D. Under general anesthesia, the skull was drilled and tumor blocks were implanted...
June 2015: Experimental and Therapeutic Medicine
Omar M Ghanem, Julia Slater, Puneet Singh, Richard F Heitmiller, Joseph D DiRocco
Colorectal lipomas are the second most common benign tumors of the colon. These masses are typically incidental findings with over 94% being asymptomatic. Symptoms-classically abdominal pain, bleeding per rectum and alterations in bowel habits-may arise when lipomas become larger than 2 cm in size. Colonic lipomas are most often noted incidentally by colonoscopy. They may also be identified by abdominal imaging such as computed tomography or magnetic resonance imaging. We report a case of a sixty-one years old male who presented to our emergency room with a 6...
May 16, 2015: World Journal of Clinical Cases
M-P Debord, E Poirier, H Delgado, M Charlot, C Colin, D Raudrant, F Golfier, O Dupuis
AIM: To show the effectiveness of ultrasound-guided puncture in the treatment of lactational breast abscess and identify its risk factors. MATERIALS AND METHODS: Retrospective descriptive study at the CHU of Lyon-Sud from December 2007 to December 2013, including patients with lactational breast abscess confirmed on ultrasound and treated with antibiotics and analgesics. Realisation of ultrasound-guided needle under local anesthesia by the radiologist and washing the cavity with physiological serum...
March 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
M A Faasse, B W Lindgren, B T Frainey, C R Marcus, D M Szczodry, A P Glaser, S Suresh, E M Gong
INTRODUCTION: Regional anesthesia is often used in combination with general anesthesia for pediatric surgery, however, it is unknown if adjunctive regional blocks are beneficial to children undergoing urologic laparoscopic or robot-assisted laparoscopic (RAL) procedures. OBJECTIVE: To compare perioperative outcomes in children with adjunctive caudal blocks, transversus abdominis plane (TAP) blocks, or no regional anesthesia for common RAL surgical procedures in pediatric urology...
June 2015: Journal of Pediatric Urology
Priyanga Ranasinghe, Y Sanja Perera, J A D Supun Senaratne, Anuja Abayadeera
INTRODUCTION: During preoperative preparation, patients undergo investigations to detect asymptomatic diseases. The probability of finding significant abnormalities on such routine investigations is small, and these investigations unnecessarily increase costs of perioperative care. We evaluated current practices, compliance with national guidelines and costs of preoperative investigations at the National Hospital of Sri Lanka (NHSL). MATERIALS AND METHODS: Patients undergoing elective surgery at the general surgical units of the NHSL from June to August 2010 were included in this study...
January 2011: Anesthesia, Essays and Researches
Ziad D Baghdadi
OBJECTIVES: This study aimed to document the mid-term effects of comprehensive dental treatment under general anesthesia (DTGA) on parent-assessed children's oral health-related quality of life (COHRQoL). A second aim was to examine some epidemiological factors associated with COHRQoL and treatment outcome. STUDY DESIGN: A pretest-posttest design was followed in which parents were surveyed using the Child Oral Health Quality of Life Questionnaire before and 6-9 months after their children (age ranges 3-10 years) underwent DTGA...
February 2015: Journal of Clinical and Experimental Dentistry
A Nicholas Kurup, Jonathan M Morris, Grant D Schmit, Thomas D Atwell, John J Schmitz, Peter S Rose, Matthew R Callstrom
PURPOSE: To describe the feasibility, safety, and effectiveness of a technique using vertebral augmentation balloons to promote delivery of cement into periacetabular tumors after cryoablation for fracture prevention. MATERIALS AND METHODS: A retrospective review was performed of seven consecutive patients (six men and one woman; mean age, 64 y ± 8) with unilateral periacetabular tumors (mean size, 4.2 cm ± 1.4) treated with cryoablation and balloon-assisted osteoplasty for fracture prevention...
April 2015: Journal of Vascular and Interventional Radiology: JVIR
Alia Daoud, Jonathan P Duff, Ari R Joffe
INTRODUCTION: Delirium is common in adult intensive care, with validated tools for measurement, known risk factors and adverse neurocognitive outcomes. We aimed to determine what is known about pediatric delirium in the pediatric intensive care unit (PICU). METHODS: We conducted a systematic search for and review of studies of the accuracy of delirium diagnosis in children in the PICU. Secondary aims were to determine the prevalence, risk factors and outcomes associated with pediatric delirium...
2014: Critical Care: the Official Journal of the Critical Care Forum
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