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https://www.readbyqxmd.com/read/28646082/subcutaneous-magnesium-in-the-advanced-cancer-setting
#1
Stephen J Fenning, Steinunn R Boyce, Paul Wilson, Fran Stretton
Hypomagnesaemia can arise from a variety of causes but is particularly prevalent in cancer populations. This case report describes a patient with recurrent symptomatic hypomagnesaemia, on the background of advanced ovarian cancer and a high-output ileostomy, who was successfully managed on a daily continuous subcutaneous infusion of magnesium via a syringe pump. There is limited published information on the subcutaneous administration of magnesium and, to our knowledge, this is the first case to report its routine delivery over 24 hours in a syringe pump...
June 23, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28643313/-anastomotic-leakage-after-laparoscopic-assisted-radical-right-hemicolectomy-reason-analysis-and-management
#2
Xin Wu, Guole Lin, Huizhong Qiu, Yi Xiao, Bin Wu
OBJECTIVE: To analyze the clinical features, possible reasons and management of anastomotic leakage after laparoscopic-assisted radical right hemicolectomy. METHODS: Clinical data of 546 patients undergoing laparoscopic-assisted radical right hemicolectomy in Peking Union Medical College Hospital from October 2010 to September 2016 were retrospectively analyzed. The occurrence of anastomotic leakage and its countermeasures were evaluated. RESULTS: Among 546 patients, 8(1...
June 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28638838/kaposi-sarcoma-mimicking-acute-flare-of-ulcerative-colitis
#3
Vivek Kumar, Parita Soni, Mohit Garg, Madina Abduraimova, Jonathan Harris
Besides an AIDS-defining illness, Kaposi sarcoma (KS) is also seen in individuals on long-term immunosuppressant therapy. We report KS in a 70-year-old immunocompetent man, which initially mimicked acute flare of ulcerative colitis (UC). He was hospitalized multiple times for complaints of watery diarrhea and tenesmus. Despite treatment with mesalamine, short courses of methylprednisolone, and one dose of infliximab, his symptoms improved only partially. He underwent colonoscopy, which revealed mild active colitis and a mass in the ascending colon...
April 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28638287/use-of-sodium-hyaluronate-carboxymethylcellulose-bioresorbable-membrane-in-loop-ileostomy-construction-facilitates-stoma-closure
#4
Danielle M Bertoni, Kerry L Hammond, David E Beck, Terry C Hicks, Charles B Whitlow, H David Vargas, David A Margolin
BACKGROUND: Loop ileostomy is a common adjunct to surgical procedures for low rectal cancers and inflammatory bowel disease. Ileostomy closure through a limited incision can be technically challenging. We hypothesized that placing a sodium hyaluronate/carboxymethylcellulose (SH/CMC) bioresorbable membrane at loop ileostomy creation would decrease stoma closure time without increasing morbidity. METHODS: In a retrospective review at a single institution with 6 board-certified colorectal surgeons, patients with loop ileostomy creation and closure between September 1999 and December 2011 were grouped based on SH/CMC placement at ileostomy creation...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/28627732/the-acute-effect-of-loperamide-on-ileostomy-output-a-randomized-double-blinded-placebo-controlled-cross-over-study
#5
Katrine Kristensen, Niels Qvist
High stoma output is a common problem in patients with ileostomy and can lead to dehydration and electrolyte disturbances. The first drug of choice to reduce stoma output is often loperamide. The aim was to assess the acute effect of loperamide on (a) ileostomy output in g/day, (b) gastrointestinal transit time and (c) patient-reported effects. A total of 12 patients completed this double-blinded, randomized, placebo-controlled, cross-over study, consisting of a 3-day treatment period with loperamide 12 mg/day or placebo followed by the reverse after a washout period of 5-7 days...
June 19, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28622070/loop-ileostomy-mediated-fecal-stream-diversion-is-associated-with-microbial-dysbiosis
#6
Emma L Beamish, Judith Johnson, Elisabeth J Shaw, Nigel A Scott, Arnab Bhowmick, Rachael J Rigby
Loop ileostomy is an effective procedure to protect downstream intestinal anastomoses. Ileostomy reversal surgery is often carried out within 12 months of formation but is associated with substantial morbidity due to severe post-operative complications. Distal ileum is deprived of enteral nutrition and rendered inactive, often becoming atrophied and fibrotic. This study aimed to investigate the microbial and morphological changes that occur in the defunctioned ileum following loop ileostomy-mediated faecal stream diversion...
June 16, 2017: Gut Microbes
https://www.readbyqxmd.com/read/28616722/duhamel-operation-for-children-with-distal-colonic-dysmotility
#7
Yew-Wei Tan, Osvaldo Borrelli, Keith Lindley, Nikhil Thapar, Joe Curry
PURPOSE: To report outcomes of children with constipation refractory to medical management and manometrically proven distal colonic dysmotility, managed with rectosigmoidectomy followed by Duhamel operation (Duhamel). METHODS: Children who underwent a Duhamel from 2009 onwards for intractable constipation and left colonic dysmotility were retrospectively reviewed. The primary end point was resolution of constipation, and secondary end point was postoperative complications...
June 14, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28615946/treatment-and-outcome-of-intestinal-perforation-after-liver-transplant-surgery-in-adults-a-single-center-experience
#8
Jianyu Lin, Jing Wang, Peng Yue, Xingmao Zhang, Ren Lang, Yuan Wang, Chen Cui, Qiang He
OBJECTIVE: Intestinal perforation is a rare complication after liver transplantation. This study was designed to calculate the incidence and investigate the outcomes of intestinal perforation in adult liver transplant patients. MATERIALS AND METHODS: The clinical records of liver transplant recipients between January 2014 and June 2016 were obtained. The incidence of intestinal perforation was calculated, and high risk factors were analyzed. RESULTS: The mean operative time was 8...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28614620/a-systematic-review-of-segmental-vs-subtotal-colectomy-and-subtotal-colectomy-vs-total-proctocolectomy-for-colonic-crohn-s-disease
#9
REVIEW
Imerio Angriman, Giovanni Pirozzolo, Romeo Bardini, Francesco Cavallin, Carlo Castoro, Marco Scarpa
AIM: Surgical management of colonic Crohn's disease (CD) is still unclear because different procedures can be adopted. The choice of operation is dependent on the involvement of colonic disease but the advantages and disadvantages of the extent of resection are still debated. METHOD: The aim of the present study is to evaluate the differences in short-term and long-term outcomes of adult patients with colonic CD, who underwent either subtotal colectomy and ileorectal anastomosis (STC) or segmental colectomy (SC) or total proctocolectomy and end ileostomy (TPC)...
June 14, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28614561/association-of-preoperative-anti-tumor-necrosis-factor-therapy-with-adverse-postoperative-outcomes-in-patients-undergoing-abdominal-surgery-for-ulcerative-colitis
#10
Audrey S Kulaylat, Afif N Kulaylat, Eric W Schaefer, Andrew Tinsley, Emmanuelle Williams, Walter Koltun, Christopher S Hollenbeak, Evangelos Messaris
Importance: Despite the increasing use of anti-tumor necrosis factor (TNF) therapy in ulcerative colitis, its effects on postoperative outcomes remain unclear, with many patients requiring surgical intervention despite optimal medical management. Objective: To assess the association of preoperative use of anti-TNF agents with adverse postoperative outcomes. Design, Setting, and Participants: This analysis used insurance claims data from a large national database to identify patients 18 years or older with ulcerative colitis...
June 14, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28612145/transanal-hartmann-s-colostomy-reversal-assisted-by-laparoscopy-outcomes-of-the-first-10-patients
#11
Jean-Sébastien Trépanier, María Clara Arroyave, Raquel Bravo, Marta Jiménez-Toscano, Francisco B DeLacy, María Fernandez-Hevia, Antonio M Lacy
INTRODUCTION: Restoration of intestinal continuity after Hartmann's procedure is a technically difficult surgery associated with significant morbidity and mortality. This study presents the short-term results of a new approach: a transanal Hartmann's colostomy reversal assisted by laparoscopy. METHOD: This is a retrospective analysis of data collected in one tertiary hospital, from October 2013 to November 2015. RESULTS: During the study period, there were ten cases of transanal Hartmann's reversal...
June 13, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28612116/prevention-of-parastomal-hernia-in-the-emergency-setting
#12
Anna Lykke, Johnny F B Andersen, Lars N Jorgensen, Tommie Mynster
AIM: This study assessed safety and efficacy associated with hernia prophylaxis using a retromuscular slowly resorbable synthetic mesh for stoma reinforcement. METHOD: This was a cohort study with a historic reference group. The study took place in a high-volume surgical department. During a 2-year period (July 2012-July 2014), we included 109 patients undergoing emergency surgery with formation of ileostomy or colostomy. All patients received a retromuscular slowly resorbable synthetic mesh (TIGR®, Novus Scientific) at the stoma site...
June 14, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28601441/evaluation-and-handling-of-constipation-in-critical-patients
#13
J Pérez-Sánchez, J Fernández-Boronat, E Martínez-Méndez, M L Marín-Cagigas, D Mota-Puerto, M C Pérez-Román, G Martínez-Estalella
OBJECTIVE: To evaluate the effectiveness of nursing care against constipation and to identify, analyze and evaluate causes and consequences. METHODOLOGY: Observational, descriptive and prospective study in polyvalent ICU tertiary hospital (2013-2015). INCLUSION CRITERIA: >18 years, stay >7 days, connected to respiratory support, with nasogastric tube and enteral or mixed nutrition. Patients with gastrointestinal pathology, encephalopathic and jejunostomy/ileostomy were excluded...
June 7, 2017: Enfermería Intensiva
https://www.readbyqxmd.com/read/28601030/aggressive-gastrointestinal-food-allergy-in-neonates-and-its-possible-relationship-to-necrotizing-enterocolitis
#14
Kazuto Suda, Toshihiro Yanai, Miki Toma, Tsubasa Aiyoshi, Takato Sasaki, Toshihiro Muraji
INTRODUCTION: The incidence of gastrointestinal food allergy (FA) in neonates is increasing. Despite this, cases of patients with gastrointestinal FA who develop necrotizing enterocolitis (NEC) requiring laparotomy are extremely rare. PRESENTATION OF CASE: We describe two cases that presented with bloody stool with a probable diagnosis of FA as eosinophils were positive in the stool at onset. Both cases failed conservative treatment. Jejunostomy and ileostomy were performed in both cases due to secondary NEC with underlying acute FA...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28595172/routine-pouchoscopy-prior-to-ileostomy-takedown-may-not-be-necessary-in-patients-with-chronic-ulcerative-colitis
#15
Jennifer X Cai, Jasmine Barrow, Alyssa Parian, Steven R Brant, Sharon Dudley-Brown, Jonathan Efron, Sandy Fang, Susan Gearhart, Michael Marohn, Bashar Safar, Brindusa Truta, Elizabeth Wick, Mark Lazarev
BACKGROUND: Creation of a J pouch is the gold standard surgical intervention in the treatment of chronic ulcerative colitis (UC). Pouchoscopy prior to ileostomy takedown is commonly performed. We describe the frequency, indication, and findings on pouchoscopy, and determine if pouchoscopy affects rates of complications after takedown. METHODS: All UC or indeterminate inflammatory bowel disease patients with a J pouch were retrospectively evaluated from January 1994 to December 2014...
June 9, 2017: Digestive Diseases
https://www.readbyqxmd.com/read/28588770/radiation-associated-colon-cancer-a-case-report
#16
Kazuhito Sasaki, Soichiro Ishihara, Keisuke Hata, Tomomichi Kiyomatsu, Hiroaki Nozawa, Kazushige Kawai, Toshiaki Tanaka, Takeshi Nishikawa, Kensuke Otani, Koji Yasuda, Manabu Kaneko, Koji Murono, Hiroyuki Abe, Teppei Morikawa, Toshiaki Watanabe
Radiation-associated colon cancer is a rare clinical entity. We herein describe the case of a patient with radiation-associated colon cancer who had undergone low anterior resection for rectal cancer following preoperative radiotherapy. Certain characteristics of radiation-associated colon cancer are highlighted. The patient was a 48-year-old man who had undergone low anterior resection for rectal cancer following preoperative radiotherapy at a total dose of 50 Gy, at the age of 29 years. When the patient presented at the University of Tokyo Hospital, 19 years after the surgery, he complained of severe anal pain and frequent defecation...
June 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28585842/-inflammatory-bowel-disease-during-pregnancy-and-childbirth
#17
K Závorová
OBJECTIVE: The aim is to give basic information about inflammatory bowel disease (IBD) during pregnancy, to highlight the importance of treatment in pregnancy and also show our own experience with the issue. DESIGN: Original work - a retrospective study. SETTING: Department of Obstetrics and Gynecology, Hospital Hořovice. RESULTS: We provide basic overview information about inheritance, fertility, mutual influence of IBD and pregnancy therapy in pregnancy and childbirth options for patients with IBD...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28583540/living-donor-liver-transplantation-for-progressive-familial-intrahepatic-cholestasis-type-1-two-reported-cases
#18
Y Oya, Y Sugawara, M Honda, D Yoshii, K Isono, S Hayashida, H Yamamoto, Y Inomata
BACKGROUND: Progressive familial intrahepatic cholestasis type 1 (PFIC1) is an inherited disease characterized by cholestatic features. We report two patients with PFIC1 who underwent liver retransplantation. CASE REPORT: One patient was a 3-year-old female who underwent liver transplantation for PFIC1. She presented with severe diarrhea and fatty liver, and went into liver failure. She therefore underwent liver retransplantation and external biliary diversion 8 years after the initial liver transplantation...
June 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28576693/direct-laparoscopic-trocar-insertion-lessons-learned-from-nine-litigated-cases
#19
George A Vilos, Artin Ternamian, Angelos G Vilos, Basim Abu-Rafea, Cici Zhu
STUDY OBJECTIVE: To report circumstances and clinical and medico-legal outcomes of nine litigated cases associated with direct trocar insertion (DTI) injuries to bowel (7 cases) and major vessel (2 cases) during primary laparoscopic access. DESIGN: Case series from 1990 through 2015. PATIENTS: Nine litigated cases. INTERVENTION: Retrospective review of medical and legal records of litigated cases in Canada reviewed by the primary author (GAV)...
May 30, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28574928/clinical-and-economic-burden-of-peristomal-skin-complications-in-patients-with-recent-ostomies
#20
Charu Taneja, Debra Netsch, Bonnie Sue Rolstad, Gary Inglese, Lois Lamerato, Gerry Oster
PURPOSE: The purpose of this study was to estimate the risk and economic burden of peristomal skin complications (PSCs) in a large integrated healthcare system in the Midwestern United States. DESIGN: Retrospective cohort study. SUBJECTS AND SETTING: The sample comprised 128 patients; 40% (n = 51) underwent colostomy, 50% (n = 64) underwent ileostomy, and 10% (n = 13) underwent urostomy. Their average age was 60.6 ± 15.6 years at the time of ostomy surgery...
June 1, 2017: Journal of Wound, Ostomy, and Continence Nursing
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