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https://www.readbyqxmd.com/read/28444772/multi-atlas-approach-with-local-registration-goodness-weighting-for-mri-based-electron-density-mapping-of-head-and-neck-anatomy
#1
Reza Farjam, Neelam Tyagi, Harini Veeraraghavan, Aditya Apte, Kristen Zakian, Margie A Hunt, Joseph O Deasy
PURPOSE: The growing use of magnetic resonance imaging (MRI) as a substitute for computed tomography-based treatment planning requires the development of effective algorithms to generate electron density maps for treatment planning and patient setup verification. The purpose of this work was to develop a method to synthesize computerized tomography (CT) for MR-only radiotherapy of head and neck cancer patients. METHODS: The algorithm is based on registration of multiple patient datasets containing both MRI and CT images (a "multi-atlas" algorithm)...
April 26, 2017: Medical Physics
https://www.readbyqxmd.com/read/28444458/the-potential-of-ehealth-in-otorhinolaryngology-head-and-neck-surgery-patients-perspectives
#2
Martin Holderried, C Ernst, F Holderried, M Rieger, G Blumenstock, A Tropitzsch
The use of modern information and communication technologies (ICT) in daily life has significantly increased during the last several years. These essential online technologies have also found their way into the healthcare system. The use of modern ICT for health reasons can be summarized by the term 'eHealth'. Despite the potential importance of eHealth in the field of otorhinolaryngology (ORL), there is little understanding of patients' attitudes towards the deeper integration of these technologies into intersectoral care...
April 25, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28444168/mechanical-versus-bioprosthetic-aortic-valve-replacement
#3
Stuart J Head, Mevlüt Çelik, A Pieter Kappetein
Mechanical valves used for aortic valve replacement (AVR) continue to be associated with bleeding risks because of anticoagulation therapy, while bioprosthetic valves are at risk of structural valve deterioration requiring reoperation. This risk/benefit ratio of mechanical and bioprosthetic valves has led American and European guidelines on valvular heart disease to be consistent in recommending the use of mechanical prostheses in patients younger than 60 years of age. Despite these recommendations, the use of bioprosthetic valves has significantly increased over the last decades in all age groups...
April 20, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28443698/impact-of-maternal-nutritional-supplementation-in-conjunction-with-a-breastfeeding-support-program-on-breastfeeding-performance-birth-and-growth-outcomes-in-a-vietnamese-population
#4
Dieu T T Huynh, Nga T Tran, Lam T Nguyen, Yatin Berde, Yen Ling Low
PURPOSE: This study aimed to evaluate the effects of maternal nutritional supplementation (MNS) in conjunction with a breastfeeding support program on birth outcomes and breastfeeding performance. METHODS: A total of 228 singleton Vietnamese mothers aged 20 to 35 years at 26 to 29 weeks of gestation with pre-pregnancy body mass index (BMI) <25.0 kg/m(2) were randomized to the intervention (n = 114), receiving MNS (252 kcal/day) daily up to 12 weeks postpartum and 4 breastfeeding education and support sessions or to the control (n = 114), receiving standards of care...
April 26, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28443331/coupling-between-the-dynamics-of-water-and-surfactants-in-lyotropic-liquid-crystals
#5
Jesse Gatten McDaniel, Arun Yethiraj
Bilayers composed of lipid or surfactant molecules are central to biological membranes and lamellar lyotropic liquid crystalline (LLC) phases. Common to these systems are phases that exhibit either ordered or disordered packing of the hydrophobic tails. In this work, we study the impact of surfactant ordering, i.e., disordered Lα and ordered Lβ LLC phases, on the dynamics of water in the lamellar phases of dicarboxylate gemini surfactants. We study the different phases at identical hydration levels by changing the length of the hydrophobic tails; surfactants with shorter tails form Lα phases and those with longer tails form Lβ phases...
April 26, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28441406/head-and-pelvic-movement-asymmetries-at-trot-in-riding-horses-in-training-and-perceived-as-free-from-lameness-by-the-owner
#6
Marie Rhodin, Agneta Egenvall, Pia Haubro Andersen, Thilo Pfau
Recent studies evaluating horses in training and considered free from lameness by their owners have identified a large proportion of horses with motion asymmetries. However the prevalence, type and magnitude of asymmetries when trotting in a straight line or on the lunge have not been investigated. The aim of this study was to objectively investigate the presence of motion asymmetries in riding horses in training by identifying the side and quantifying the degree and type (impact, pushoff) of forelimb and hind limb asymmetries found during straight line trot and on the lunge...
2017: PloS One
https://www.readbyqxmd.com/read/28441371/multimodal-imaging-of-head-and-neck-squamous-cell-carcinoma
#7
Kenneth L Gage, Kerry Thomas, Daniel Jeong, Dexter G Stallworth, John A Arrington
BACKGROUND: The role of imaging in the staging, treatment planning, and ongoing surveillance of patients with head and neck squamous cell carcinoma (HNSCC) continues to evolve. Changes in patient demographics, treatment paradigms, and technology present opportunities and challenges for the management of HNSCC. METHODS: The general indications and usage of standard and multimodal cross-sectional imaging in the evaluation and management of HNSCC are reviewed, with an emphasis on incorporating them into treatment pathways...
April 2017: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/28437225/neck-collar-with-mild-jugular-vein-compression-ameliorates-brain-activation-changes-during-a-working-memory-task-after-a-season-of-high-school-football
#8
Weihong Yuan, James Leach, Thomas Maloney, Mekibib Altaye, David Smith, Paul Gubanich, Kim Barber-Foss, Staci Thomas, Christopher DiCesare, Adam Kiefer, Gregory D Myer
Emerging evidence indicates that repetitive head impacts, even at a sub-concussive level, may result in exacerbated or prolonged neurologic deficits in athletes. This study aimed to: 1) quantify the effect of repetitive head impacts on the alteration of neuronal activity based on fMRI of working memory after a high school football season; and 2) determine whether a neck collar that applies mild jugular vein compression to reduce brain energy absorption in head impact through slosh mitigation can ameliorate the altered fMRI activation during a working memory task...
February 18, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28437010/technical-note-comparison-of-peripheral-patient-dose-from-mr-guided-60-co-therapy-and-6mv-linear-accelerator-igrt
#9
Pascal Hauri, Roger A Hälg, Uwe Schneider
PURPOSE: The use of X-ray imaging in radiation therapy can give a substantial dose to the patient. A Cobalt machine combined with an magnetic resonance imaging (MRI) was recently introduced to clinical work. One positive aspect of using non-ionizing imaging devices is the reduction of the patient exposure. The purpose of this study was to quantify the difference in out-of-field dose to the patient between the image guided radiation therapy (IGRT) treatment applied with a linear accelerator with cone beam CT (CBCT) equipment and a Cobalt machine combined with an MRI...
April 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28436738/brainstem-injury-in-motor-vehicle-crashes
#10
David C Viano, Chantal S Parenteau
OBJECTIVE: This is a descriptive study of the frequency and risk for brainstem injury by crash type, belt use and crash severity (delta V). NASS-CDS electronic cases were reviewed to see if the transition from vehicles without advanced airbags and seatbelts, side airbags and curtains to vehicles with the safety technologies has influenced the risk for brainstem injury. METHODS: 1994-2013 NASS-CDS was analyzed to determine the number of brainstem injuries in non-ejected adults (15+ year old) in vehicle crashes...
March 1, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28432841/comparison-of-pneumatic-tube-system-with-manual-transport-for-routine-chemistry-hematology-coagulation-and-blood-gas-tests
#11
Alex Pupek, Beverly Matthewson, Erin Whitman, Rachel Fullarton, Yu Chen
BACKGROUND: The pneumatic tube system (PTS) is commonly used in modern clinical laboratories to provide quick specimen delivery. However, its impact on sample integrity and laboratory testing results are still debatable. In addition, each PTS installation and configuration is unique to its institution. We sought to validate our Swisslog PTS by comparing routine chemistry, hematology, coagulation and blood gas test results and sample integrity indices between duplicate samples transported either manually or by PTS...
April 22, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28432671/investigation-of-the-physical-effects-of-respiratory-motion-compensation-in-a-large-population-of-patients-undergoing-tc-99m-cardiac-perfusion-spect-ct-stress-imaging
#12
P Hendrik Pretorius, Karen L Johnson, Seth T Dahlberg, Michael A King
BACKGROUND: Respiratory motion can deteriorate image fidelity in cardiac perfusion SPECT. We determined the extent of respiratory motion, assessed its impact on image fidelity, and investigated the existence of gender differences, thereby examining the influence of respiratory motion in a large population of patients. METHODS: One thousand one hundred and three SPECT/CT patients underwent visual tracking of markers on their anterior surface during stress acquisition to track respiratory motion...
April 21, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28430715/computed-tomography-of-the-head-and-neck-region-for-tumor-staging-comparison-of-dual-source-dual-energy-and-low-kilovolt-single-energy-acquisitions
#13
Matthias Stefan May, Joscha Bruegel, Michael Brand, Marco Wiesmueller, Bernhard Krauss, Thomas Allmendinger, Michael Uder, Wolfgang Wuest
PURPOSE: The aim of this study was to intra-individually compare the image quality obtained by dual-source, dual-energy (DSDE) computed tomography (CT) examinations and different virtual monoenergetic reconstructions to a low single-energy (SE) scan. MATERIALS AND METHODS: Third-generation DSDE-CT was performed in 49 patients with histologically proven malignant disease of the head and neck region. Weighted average images (WAIs) and virtual monoenergetic images (VMIs) for low (40 and 60 keV) and high (120 and 190 keV) energies were reconstructed...
April 20, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28430697/abusive-head-trauma-and-mortality-an-analysis-from-an-international-comparative-effectiveness-study-of-children-with-severe-traumatic-brain-injury
#14
Nikki Miller Ferguson, Ajit Sarnaik, Darryl Miles, Nadeem Shafi, Mark J Peters, Edward Truemper, Monica S Vavilala, Michael J Bell, Stephen R Wisniewski, James F Luther, Adam L Hartman, Patrick M Kochanek
OBJECTIVES: Small series have suggested that outcomes after abusive head trauma are less favorable than after other injury mechanisms. We sought to determine the impact of abusive head trauma on mortality and identify factors that differentiate children with abusive head trauma from those with traumatic brain injury from other mechanisms. DESIGN: First 200 subjects from the Approaches and Decisions in Acute Pediatric Traumatic Brain Injury Trial-a comparative effectiveness study using an observational, cohort study design...
April 20, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28430523/altered-expression-of-mirnas-is-related-to-larynx-cancer-tnm-stage-and-patients-smoking-status
#15
Antoni Bruzgielewicz, Ewa Osuch-Wojcikiewicz, Kazimierz Niemczyk, Olga Sieniawska-Buccella, Mateusz Siwak, Anna Walczak, Alicja Nowak, Ireneusz Majsterek
It has been reported that microRNAs (miRNAs) are responsible for acquiring all the hallmarks of cancer cells, as well as have a significant impact on the clinical management of cancers at every stage, including prognosis, remission, relapse, and metastasis. In this study, we investigated the association of miR-29a-3p, miR-202-3p, miR-3713, miR-4768-3p, and miR-548aa expression with clinicopathologic features in patients suffering from laryngeal cancer (LC) and determined the potential role of studied miRNAs in the progression of LC...
April 21, 2017: DNA and Cell Biology
https://www.readbyqxmd.com/read/28429139/rates-of-parasitism-but-not-allocation-of-egg-resources-vary-among-and-within-hosts-of-a-generalist-avian-brood-parasite
#16
Loren Merrill, Scott J Chiavacci, Ryan T Paitz, Thomas J Benson
Brown-headed cowbirds (Molothrus ater) deposit their eggs into the nests of other birds, which then raise the cowbird chick. Female cowbirds thus have limited options for impacting their offspring's development via maternal effects compared to most other passerines. Cowbirds can impact their offspring's phenotype by choosing among potential host nests, and by adjusting egg resources based on host characteristics. To examine whether cowbirds exhibit either or both of these strategies, we investigated rates of cowbird parasitism and egg investment (egg size, yolk-to-albumen ratio, and yolk testosterone and androstenedione) among and within host species in a shrubland bird community...
April 20, 2017: Oecologia
https://www.readbyqxmd.com/read/28427480/lessons-from-a-large-trauma-center-impact-of-blunt-chest-trauma-in-polytrauma-patients-still-a-relevant-problem
#17
REVIEW
Konstantina Chrysou, Gabriel Halat, Beatrix Hoksch, Ralph A Schmid, Gregor J Kocher
BACKGROUND: Thoracic trauma is the third most common cause of death after abdominal injury and head trauma in polytrauma patients. The purpose of this study was to investigate epidemiological data, treatment and outcome of polytrauma patients with blunt chest trauma in order to help improve management, prevent complications and decrease polytrauma patients' mortality. METHODS: In this retrospective study we included all polytrauma patients with blunt chest trauma admitted to our tertiary care center emergency department for a 2-year period, from June 2012 until May 2014...
April 20, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/28426877/knockdown-of-hnrnpk-leads-to-increased-dna-damage-after-irradiation-and-reduces-survival-of-tumor-cells
#18
Nadine Wiesmann, Judith Strozynski, Carina Beck, Nadine Zimmermann, Simone Mendler, Rita Gieringer, Irene Schmidtmann, Jürgen Brieger
Radiotherapy is an important treatment option in the therapy of multiple tumor entities among them head and neck squamous cell carcinoma (HNSCC). However, the success of radiotherapy is limited by the development of radiation resistances. Heterogeneous nuclear ribonucleoprotein K (hnRNPK) is a cofactor of p53 and represents a potential target for radio sensitization of tumor cells. In this study, we analyzed the impact of hnRNPK on the DNA damage response after gamma irradiation. By yH2AX foci analysis, we found that hnRNPK knockdown increases DNA damage levels in irradiated cells...
March 1, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/28422945/growth-pattern-and-final-height-of-very-preterm-versus-very-low-birth-weight-infants
#19
Jonneke J Hollanders, Sylvia M van der Pal, Paula van Dommelen, Joost Rotteveel, Martijn Jj Finken
BACKGROUND: Both very preterm (VP; i.e., gestational age <32 weeks) and very low birth weight (VLBW; i.e., birth weight <1,500 grams) are used as inclusion criteria by studies on preterm birth. We aimed to quantify the impact of these entities on postnatal growth until final height. METHODS: Subjects born VP and/or with VLBW from the Project On Preterm and Small-for-gestational-age infants cohort were classified as: (1) VP+/VLBW+ (n=495), (2) VP+/VLBW- (n=207) or (3) VP-/VLBW+ (n=296) infants...
April 19, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28421875/three-dimensional-printing-and-its-applications-in-otorhinolaryngology-head-and-neck-surgery
#20
Trevor D Crafts, Susan E Ellsperman, Todd J Wannemuehler, Travis D Bellicchi, Taha Z Shipchandler, Avinash V Mantravadi
Objective Three-dimensional (3D)-printing technology is being employed in a variety of medical and surgical specialties to improve patient care and advance resident physician training. As the costs of implementing 3D printing have declined, the use of this technology has expanded, especially within surgical specialties. This article explores the types of 3D printing available, highlights the benefits and drawbacks of each methodology, provides examples of how 3D printing has been applied within the field of otolaryngology-head and neck surgery, discusses future innovations, and explores the financial impact of these advances...
November 1, 2016: Otolaryngology—Head and Neck Surgery
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