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https://www.readbyqxmd.com/read/28813838/developing-safe-fall-strategies-for-lower-limb-exoskeletons
#1
Mahsa Khalili, Jaimie F Borisoff, H F Machiel Van der Loos
One of the main challenges in the use of a powered lower limb exoskeleton (LLE) is to ensure that balance is maintained throughout the operation of the device. Since no control strategy has yet been implemented that prevents falls in the case of a loss of balance, head or other serious injuries may occur during independent use of LLEs in the event of a fall. These safety concerns limit LLEs in the community to supervised use only. Using the backward fall as a model, we used optimization techniques to develop safe fall control strategies in order to avoid head impact and mitigate the impact velocity of the hips...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813627/the-impact-on-resource-utilization-of-supportive-care-consults-on-patients-at-the-university-of-north-carolina-hospital-2010-2012
#2
Kristen Westfall, Dominic Moore, Matthew Meeneghan, Sandra Jarr, John Valgus, Stephen Bernard
BACKGROUND: Cancer patients have a high rate of emergency department (ED) visits and inpatient hospitalizations (IHs) that may be reduced by use of outpatient palliative care services. OBJECTIVE: To determine whether the outpatient adult palliative care service at the University of North Carolina (UNC) Hospital, begun in 2008, reduced the frequency of ED visits and IH during a two-year period. DESIGN: The charts of patients with lung cancer or head and neck cancer seen by the supportive care service from 2010 to 2011, and of a contemporaneous set of potential consults that were not seen, were retrospectively reviewed to determine the impact of this care delivery model...
August 16, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28813547/an-experimental-and-numerical-study-of-hybrid-iii-dummy-response-to-simulated-underbody-blast-impacts
#3
Karthik Somasundaram, Anil Kalra, Don Sherman, Paul Begeman, King H Yang, John M Cavanaugh
Anthropometric test devices (ATDs) such as Hybrid III dummy have been widely used in automotive crash tests to evaluate the risks of injury at different body regions. In recent years, researchers have started using automotive ATDs to study the high-speed vertical loading response caused by underbelly blast (UBB) impacts. This study analyzed the Hybrid III dummy responses to short-duration large magnitude vertical acceleration in a laboratory setup. Two unique test conditions were investigated using a horizontal sled system to simulate the UBB loading conditions...
August 16, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28812151/high-clinical-impact-and-diagnostic-accuracy-of-eus-guided-biopsy-sampling-of-subepithelial-lesions-a-prospective-comparative-study
#4
Per Hedenström, Hanns-Ulrich Marschall, Bengt Nilsson, Akif Demir, Björn Lindkvist, Ola Nilsson, Riadh Sadik
BACKGROUND: In a tertiary center setting we aimed to study the diagnostic accuracy and clinical impact of EUS-guided biopsy sampling (EUS-FNB) with a reverse bevel needle compared with that of fine needle aspiration (EUS-FNA) in the work-up of subepithelial lesions (SEL). METHODS: All patients presenting with SELs referred for EUS-guided sampling were prospectively included in 2012-2015. After randomization of the first pass modality, dual sampling with both EUS-FNB and EUS-FNA was performed in each lesion...
August 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28812060/reolysin-and-histone-deacetylase-inhibition-in-the-treatment-of-head-and-neck-squamous-cell-carcinoma
#5
Alena C Jaime-Ramirez, Jun-Ge Yu, Enrico Caserta, Ji Young Yoo, Jianying Zhang, Tae Jin Lee, Craig Hofmeister, John H Lee, Bhavna Kumar, Quintin Pan, Pawan Kumar, Robert Baiocchi, Theodoros Teknos, Flavia Pichiorri, Balveen Kaur, Matthew Old
Oncolytic viruses (OVs) are emerging as powerful anti-cancer agents and are currently being tested for their safety and efficacy in patients. Reovirus (Reolysin), a naturally occurring non-pathogenic, double-stranded RNA virus, has natural oncolytic activity and is being tested in phase I-III clinical trials in a variety of tumor types. With its recent US Food and Drug Administration (FDA) orphan drug designation for several tumor types, Reolysin is a potential therapeutic agent for various cancers, including head and neck squamous cell carcinomas (HNSCCs), which have a 5-year survival of ∼55%...
June 16, 2017: Molecular Therapy Oncolytics
https://www.readbyqxmd.com/read/28812036/incidence-of-sports-related-concussion-among-ncaa-women-s-ice-hockey-athletes
#6
Emily M Brook, Emily Kroshus, Caroline H Hu, Marissa Gedman, Jamie E Collins, Elizabeth G Matzkin
BACKGROUND: There are limited data on the incidence of concussion and concussion symptom nondisclosure among collegiate women's ice hockey athletes. PURPOSE: To determine the incidence of sports-related concussion (SRC) in National Collegiate Athletic Association (NCAA) women's ice hockey athletes. STUDY DESIGN: Descriptive epidemiology study. METHODS: An anonymous online survey was completed by 459 NCAA women's ice hockey athletes...
July 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28811489/high-temperature-stress-during-flowering-and-grain-filling-offsets-beneficial-impact-of-elevated-co2-on-assimilate-partitioning-and-sink-strength-in-rice
#7
Ashish K Chaturvedi, Rajeev N Bahuguna, Divya Shah, Madan Pal, S V Krishna Jagadish
Elevated [CO2] (e[CO2]) environments have been predicted to improve rice yields under future climate. However, a concomitant rise in temperature could negate e[CO2] impact on plants, presenting a serious challenge for crop improvement. High temperature (HT) stress tolerant NL-44 and high yielding basmati Pusa 1121 rice cultivars, were exposed to e[CO2] (from panicle initiation to maturity) and a combination of e[CO2] + HT (from heading to maturity) using field based open top chambers. Elevated [CO2] significantly increased photosynthesis, seed-set, panicle weight and grain weight across both cultivars, more prominently with Pusa 1121...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28810995/chondrocyte-viability-after-a-simulated-blast-exposure
#8
K Aaron Shaw, Peter C Johnson, David Williams, Steven D Zumbrun, Richard Topolski, Craig D Cameron
OBJECTIVES: The effects of blast exposure have gained increasing interest in the military medical community with their continued occurrence on the battlefield. The impact of the direct and indirect energy imparted from blasts to hollow viscera, as well as closed head injuries, have been well studied. However, the injury to articular cartilage has not been investigated, despite previous correlations regarding the development of osteoarthritis. The purpose of this study was to assess the degree of injury to articular chondrocytes after exposure to a simulated blast overpressure wave...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28809632/cerclage-breakage-in-trochanteric-revision-high-risk-for-hip-endoprosthesis
#9
M J Kraus, A M Nowakowski
We report a 72-year-old man who underwent fixation with a multifilament cerclage system after a peri-prosthetic trochanteric fracture (Vancouver A1). Failure of cerclage occurred after 23 month and revision of trochanteric attachment was performed due to non-union. Intraoperatively fragments of the cable were found between prosthesis head and liner. Cup and head were changed and the greater trochanter was re-attached after allograft-impaction. Based on the present case report multifilament cerclage cables should be used with precaution and might require a close and frequent follow-up given the possibility of cerclage breakage and consecutive catastrophic wear by migration of cerclage particles...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28807936/genomic-alterations-in-circulating-tumor-dna-from-diverse-cancer-patients-identified-by-next-generation-sequencing
#10
Maria Schwaederle, Ranajoy Chattopadhyay, Shumei Kato, Paul T Fanta, Kimberly C Banks, In Sil Choi, David E Piccioni, Sadakatsu Ikeda, AmirAli Talasaz, Richard B Lanman, Lyudmila Bazhenova, Razelle Kurzrock
Non-invasive genomic profiling of tumors may be possible with next-generation sequencing (NGS) of blood-derived circulating tumor DNA (ctDNA), but proof of concept in a large cohort <p>of patients with diverse cancers has yet to be reported. Here we report the results of an analysis of plasma-derived ctDNA from 670 patients with diverse cancers.</p> The tumors represented in the patient cohort were mainly gastrointestinal (31.8%), brain (22.7%) or lung (20.7%). ctDNA obtained from most patients (N = 423 (63%)) displayed at least 1 alteration...
August 14, 2017: Cancer Research
https://www.readbyqxmd.com/read/28807524/peak-linear-and-rotational-acceleration-magnitude-and-duration-effects-on-maximum-principal-strain-in-the-corpus-callosum-for-sport-impacts
#11
Andrew Post, T Blaine Hoshizaki, Michael D Gilchrist, Michael D Cusimano
Concussion has been linked to the presence of injurious strains in the brain tissues. Research investigating severe brain injury has reported that strains in the brain may be affected by two parameters: magnitude of the acceleration, and duration of that acceleration. However, little is known how this relationship changes in terms of creating risk for brain injury for magnitudes and durations of acceleration common in sporting environments. This has particular implications for the understanding and prevention of concussive risk of injury in sporting environments...
July 25, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28807482/postoperative-complications-after-head-and-neck-operations-that-require-free-tissue-transfer-prevalence-morbidity-and-cost
#12
J McMahon, T P B Handley, A Bobinskas, M Elsapagh, H S Anwar, P V Ricciardo, A McLaren, R Davis, N Syyed, C MacIver, C Wales, W S Hislop, E Thomson, S Thomson, K Fitzpatrick, A Rae, R Campbell
To understand and reduce the impact of postoperative complications, we studied 568 patients who had had operations over 72 months in our hospital. Multivariate analysis indicated that factors indicative of coexisting conditions (including activated systemic inflammation) and the complexity of the operation are primary determinants of postoperative complications. The enhanced recovery after surgery (ERAS) care pathway did not have an effect on their occurrence or severity. Systematic study of patients' toleration of major head and neck operations is required, as optimal perioperative care pathways remain elusive...
August 11, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28807431/a-prospective-analysis-of-injury-rates-patterns-and-causes-in-cliff-and-splash-diving
#13
Lukas Ernstbrunner, Armin Runer, Paul Siegert, Matthäus Ernstbrunner, Johannes Becker, Thomas Freude, Herbert Resch, Philipp Moroder
INTRODUCTION: Information about injuries and its differences in Cliff Diving (CD) and Splash Diving (SD) are unknown. It was the aim to analyse (1) injury rates, patterns and causes; (2) differences (in injuries) between both disciplines; and to (3) identify targets for future injury prevention interventions. METHODS: From April to November 2013, 81 cliff and 51 splash divers were prospectively surveyed with an encrypted, monthly e-mail-based questionnaire. RESULTS: During a total of 7857h diving with an average diving height of 13 (±7)m, an overall injury rate of 7...
August 5, 2017: Injury
https://www.readbyqxmd.com/read/28807194/the-impact-of-glasgow-coma-scale-age-prognosis-score-on-geriatric-traumatic-brain-injury-outcomes
#14
Muhammad Khan, Terence O'Keeffe, Faisal Jehan, Narong Kulvatunyou, Abdullah Kattaa, Lynn Gries, Andrew Tang, Bellal Joseph
BACKGROUND: As the population ages, increasing number of geriatric patients sustain traumatic brain injury (TBI). Communication of accurate prognostic information is crucial for making informed decisions on behalf of such patients. Therefore, the aim of our study was to develop a simple and clinically applicable tool that accurately predicts the prognosis in geriatric TBI patients. METHODS: We performed a 1-y (2011) retrospective analysis of isolated geriatric TBI patients (age ≥65 y, head abbreviated injury score [AIS] ≥ 3, and other body AIS < 3) in the National Trauma Data Bank...
August 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28803584/table-talk-development-of-an-observational-tool-to-assess-verbal-feeding-communications-in-early-care-and-education-settings
#15
Taren Swindle, Julie M Rutledge, Belynda Dix, Leanne Whiteside-Mansell
OBJECTIVE: Children's dietary intake impacts weight status and a range of short- and long-term health outcomes. Accurate measurement of factors that influence children's diet is critical to the development and evaluation of interventions designed to improve children's diets. The purpose of the current paper is to present the development of the Table Talk observational tool to measure early care and education teachers' (ECET) verbal feeding communications. DESIGN: An observational tool to assess ECET verbal communication at mealtimes was deigned based on the extant literature...
August 14, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28801178/impact-of-head-and-neck-radiotherapy-on-the-mechanical-behavior-of-composite-resins-and-adhesive-systems-a-systematic-review
#16
REVIEW
Cristhian Camilo Madrid Troconis, Alan Roger Santos-Silva, Thaís Bianca Brandão, Marcio Ajudarte Lopes, Mario Fernando de Goes
OBJECTIVES: To analyze the evidence regarding the impact of head and neck radiotherapy (HNRT) on the mechanical behavior of composite resins and adhesive systems. METHODS: Searches were conducted on PubMed, Embase, Scopus and ISI Web of Science databases using "Radiotherapy", "Composite resins" and "Adhesive systems" as keywords. Selected studies were written in English and assessed the mechanical behavior of composite resins and/or adhesive systems when bonding procedure was conducted before and/or after a maximum radiation dose ≥50Gy, applied under in vitro or in vivo conditions...
August 8, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28798674/adaptive-gaze-strategies-for-locomotion-with-constricted-visual-field
#17
Colas N Authié, Alain Berthoz, José-Alain Sahel, Avinoam B Safran
In retinitis pigmentosa (RP), loss of peripheral visual field accounts for most difficulties encountered in visuo-motor coordination during locomotion. The purpose of this study was to accurately assess the impact of peripheral visual field loss on gaze strategies during locomotion, and identify compensatory mechanisms. Nine RP subjects presenting a central visual field limited to 10-25° in diameter, and nine healthy subjects were asked to walk in one of three directions-straight ahead to a visual target, leftward and rightward through a door frame, with or without obstacle on the way...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28797606/plasma-creatine-kinase-b-correlates-with-injury-severity-and-symptoms-in-professional-boxers
#18
Joseph Kilianski, Sophie Peeters, Jeff Debad, Joseph Mohmed, Steven E Wolf, Joseph P Minei, Ramon Diaz-Arrastia, Joshua W Gatson
INTRODUCTION: Each year in the United States, approximately 1.7 million people sustain a traumatic brain injury (TBI). Of these TBI events, about 75 percent are characterized as being mild brain injuries. Immediately following TBI, a secondary brain damage persists for hours, days, and even months. Previously, detection of neuronal and glial biomarkers have proven to be useful to predict neurological outcomes. Here, we hypothesized that creatine kinase, brain (CKBB) is a sensitive biomarker for acute secondary brain injury in professional boxers...
August 7, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28797454/impact-of-early-prophylactic-feeding-on-long-term-tube-dependency-outcomes-in-patients-with-head-and-neck-cancer
#19
Teresa Brown, Merrilyn Banks, Brett G M Hughes, Charles Lin, Lizbeth M Kenny, Judith D Bauer
OBJECTIVES: Prophylactic gastrostomy tube (PGT) is frequently used in patients with head and neck cancer (HNSCC). There are concerns this leads to tube dependency but this phenomena is not well defined. This study aimed to determine whether early feeding via PGT impacted on longer term tube feeding outcomes. MATERIALS AND METHODS: Patients with HNSCC with PGT were observed monthly post-treatment regarding tube use and time to removal up to twelve months. Patients were from a randomised controlled trial comparing an early feeding intervention via the PGT (n=57) versus usual care which commenced feeding when clinically indicated (n=67)...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28797450/tube-feeding-during-treatment-for-head-and-neck-cancer-adherence-and-patient-reported-barriers
#20
Teresa Brown, Merrilyn Banks, Brett G M Hughes, Charles Lin, Lizbeth Kenny, Judith Bauer
OBJECTIVES: The main aim was to investigate the incidence of patient adherence to nutritional tube feeding recommendations in patients with head and neck cancer and to determine patient barriers to meeting tube feeding prescription. MATERIALS AND METHODS: This was an observational study from a randomised controlled trial in patients with head and neck cancer deemed at high nutritional risk with prophylactic gastrostomy (n=125). Patients were randomised to receive early tube feeding prior to treatment (intervention group) or standard care...
September 2017: Oral Oncology
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