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Intracranial volume measurement

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https://www.readbyqxmd.com/read/29328001/gamma-knife-radiosurgery-of-saccular-aneurysms-in-a-rabbit-model
#1
Mark D Meadowcroft, Timothy K Cooper, Sebastian Rupprecht, Thaddeus C Wright, Elizabeth E Neely, Michele Ferenci, Weimin Kang, Qing X Yang, Robert E Harbaugh, James R Connor, James McInerney
OBJECTIVE Intracranial aneurysms are vascular abnormalities associated with neurological morbidity and mortality due to risk of rupture. In addition, many aneurysm treatments have associated risk profiles that can preclude the prophylactic treatment of asymptomatic lesions. Gamma Knife radiosurgery (GKRS) is a standard treatment for trigeminal neuralgia, tumors, and arteriovenous malformations. Aneurysms associated with arteriovenous malformations have been noted to resolve after treatment of the malformation...
January 12, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29322596/subclinical-depressive-symptoms-during-late-midlife-and-structural-brain-alterations-a-longitudinal-study-of-danish-men-born-in-1953
#2
Merete Osler, Lauge Sørensen, Maarten Rozing, Oriol Puig Calvo, Mads Nielsen, Egill Rostrup
We explored whether depressive symptoms measured three times during midlife were associated with structural brain alterations quantified using magnetic resonance imaging measurements of volume, cortical thickness, and intensity texture. In 192 men born in 1953 with depressive symptoms measured at age 51, 56, and 59 years, magnetic resonance imaging was performed at age 59. All data processing was performed using the Freesurfer software package except for the texture-scores that were computed using in-house software...
January 10, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29314208/pretreatment-lesional-volume-impacts-clinical-outcome-and-thrombectomy-efficacy
#3
Yu Xie, Catherine Oppenheim, Francis Guillemin, Vincent Gautheron, Benjamin Gory, Hélène Raoult, Sébastien Soize, Jacques Felblinger, Gabriela Hossu, Serge Bracard
OBJECTIVE: We aimed to characterize the association between pretreatment lesional volume measured on diffusion-weighted images and functional outcome, and estimate the impact on thrombectomy efficacy for ischemic stroke with anterior proximal intracranial arterial occlusion. METHODS: Anterior circulation ischemic stroke patients who had pretreatment diffusion-weighted imaging in the THRACE study were included. Lesional volume was semi-automatically segmented. Logistic regression was applied to model clinical outcome as a function of lesional volume...
January 3, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29311265/burden-of-dilated-perivascular-spaces-an-emerging-marker-of-cerebral-small-vessel-disease-is-highly-heritable
#4
Marie-Gabrielle Duperron, Christophe Tzourio, Muralidharan Sargurupremraj, Bernard Mazoyer, Aïcha Soumaré, Sabrina Schilling, Philippe Amouyel, Ganesh Chauhan, Yi-Cheng Zhu, Stéphanie Debette
BACKGROUND AND PURPOSE: The genetic contribution to dilated perivascular space (dPVS) burden-an emerging MRI marker of cerebral small vessel disease-is unknown. We measured the heritability of dPVS burden and its shared heritability with other MRI markers of cerebral small vessel disease. METHODS: The study sample comprised 1597 participants from the population-based Three City (3C) Dijon Study, with brain MRI and genome-wide genotyping (mean age, 72.8±4.1 years; 61% women)...
January 8, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29303453/stereotactic-radiosurgery-for-who-grade-i-posterior-fossa-meningiomas-long-term-outcomes-with-volumetric-evaluation
#5
Mohana Rao Patibandla, Cheng-Chia Lee, Athreya Tata, Gokul Chowdary Addagada, Jason P Sheehan
OBJECTIVE Research over the past 2 decades has been characterizing the role of stereotactic radiosurgery (SRS) in the treatment of benign intracranial tumors, including meningiomas. However, few studies have examined the long-term outcomes of SRS treatment for posterior fossa meningiomas (PFMs). Furthermore, previous studies have typically used single diameter measurements when reporting outcomes, which can yield misleading results. The authors describe the use of SRS in the treatment of benign WHO grade I PFMs and correlate volumetric analysis with long-term outcomes...
January 5, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29298649/an-inflammation-related-nutrient-pattern-is-associated-with-both-brain-and-cognitive-measures-in-a-multiethnic-elderly-population
#6
Yian Gu, Jennifer J Manly, Richard P Mayeux, Adam M Brickman
BACKGROUND: Accumulating evidence suggest that dietary factors are associated with Alzheimer's disease, and brain and cognitive health. It is unclear whether inflammation explains this association. OBJECTIVE: To examine whether an inflammation-related nutrient pattern (INP) was associated with neuroimaging and cognitive measures of brain health. METHOD: The current cross-sectional study included 330 non-demented elderly (mean age 79 years at MRI scan) participants in a multi-ethnic, community-based cohort study who had information on nutritional intakes (estimated from food frequency questionnaire), circulating C-reactive protein and interleukin-6 (measured by ELISA), MRI scans, and cognition...
January 1, 2018: Current Alzheimer Research
https://www.readbyqxmd.com/read/29282330/whole-genome-sequence-analyses-of-brain-imaging-measures-in-the-framingham-study
#7
Chloé Sarnowski, Claudia L Satizabal, Charles DeCarli, Achilleas N Pitsillides, L Adrienne Cupples, Ramachandran S Vasan, James G Wilson, Joshua C Bis, Myriam Fornage, Alexa S Beiser, Anita L DeStefano, Josée Dupuis, Sudha Seshadri
OBJECTIVE: We sought to identify rare variants influencing brain imaging phenotypes in the Framingham Heart Study by performing whole genome sequence association analyses within the Trans-Omics for Precision Medicine Program. METHODS: We performed association analyses of cerebral and hippocampal volumes and white matter hyperintensity (WMH) in up to 2,180 individuals by testing the association of rank-normalized residuals from mixed-effect linear regression models adjusted for sex, age, and total intracranial volume with individual variants while accounting for familial relatedness...
December 27, 2017: Neurology
https://www.readbyqxmd.com/read/29274112/relationships-among-neuroscore-magnetic-resonance-imaging-features-and-intracranial-pressure-in-sheep-affected-by-slow-growing-brain-lesions
#8
Maria A Evangelisti, Roberta Deiana, Valentino Melosu, Giovanni P Burrai, Isabella Ballocco, Antonio Varcasia, Antonio Scala, Maria L Manunta
Diagnosing high intracranial pressure by clinical and diagnostic imaging is particularly challenging for chronic or slow-growing lesions. The aim of this prospective case-control study is to determine whether the neuroscore and brain magnetic resonance imaging (MRI) are related to the direct measurement of intracranial pressure in sheep affected by intracranial slow-growing lesions due to chronic cerebral coenurosis (Coenurus cerebralis). Seventeen affected and 10 control sheep were included. All animals underwent a neurological examination, MRI of the brain, and direct measurement of intracranial pressure...
December 22, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/29244602/association-of-magnetic-resonance-imaging-based-preoperative-tumor-volume-with-postsurgical-survival-time-in-dogs-with-primary-intracranial-glioma
#9
Jeffrey D MacLellan, Susan A Arnold, Aditya C Dave, Matthew A Hunt, G Elizabeth Pluhar
OBJECTIVE To assess the relationship between preoperative volume of primary intracranial gliomas in dogs as determined via MRI and survival time after surgical debulking and adjunctive immunotherapy. DESIGN Retrospective cohort study. ANIMALS 47 client-owned dogs enrolled in clinical trials regarding glioma treatments. PROCEDURES Medical records of all dogs undergoing craniotomy at the University of Minnesota Veterinary Medicine Center with histologically confirmed glioma between 2008 and 2015 were retrospectively reviewed, and outcome data were collected...
January 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29229328/outcomes-after-reirradiation-for-recurrent-pediatric-intracranial-ependymoma
#10
Derek S Tsang, Elizabeth Burghen, Paul Klimo, Frederick A Boop, David W Ellison, Thomas E Merchant
PURPOSE: To determine the long-term outcomes and the optimal dose and volume for reirradiation of recurrent pediatric ependymoma. METHODS AND MATERIALS: Patients with recurrent ependymoma treated with a second course of fractionated radiation therapy (RT2) were reviewed retrospectively. Eligible patients had localized, intracranial ependymoma at initial diagnosis that was treated with focal radiation (RT1) without craniospinal irradiation (CSI) and were aged ≤21 years at the time of RT2...
October 13, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29225064/intracranial-high-%C3%AE-connectivity-distinguishes-wakefulness-from-sleep
#11
Ezequiel Mikulan, Eugenia Hesse, Lucas Sedeño, Tristán Bekinschtein, Mariano Sigman, María Del Carmen García, Walter Silva, Carlos Ciraolo, Adolfo M García, Agustín Ibáñez
Neural synchrony in the γ-band is considered a fundamental process in cortical computation and communication and it has also been proposed as a crucial correlate of consciousness. However, the latter claim remains inconclusive, mainly due to methodological limitations, such as the spectral constraints of scalp-level electroencephalographic recordings or volume-conduction confounds. Here, we circumvented these caveats by comparing γ-band connectivity between two global states of consciousness via intracranial electroencephalography (iEEG), which provides the most reliable measurements of high-frequency activity in the human brain...
December 7, 2017: NeuroImage
https://www.readbyqxmd.com/read/29220823/patterns-of-progressive-atrophy-vary-with-age-in-alzheimer-s-disease-patients
#12
Cassidy M Fiford, Gerard R Ridgway, David M Cash, Marc Modat, Jennifer Nicholas, Emily N Manning, Ian B Malone, Geert Jan Biessels, Sebastien Ourselin, Owen T Carmichael, M Jorge Cardoso, Josephine Barnes
Age is not only the greatest risk factor for Alzheimer's disease (AD) but also a key modifier of disease presentation and progression. Here, we investigate how longitudinal atrophy patterns vary with age in mild cognitive impairment (MCI) and AD. Data comprised serial longitudinal 1.5-T magnetic resonance imaging scans from 153 AD, 339 MCI, and 191 control subjects. Voxel-wise maps of longitudinal volume change were obtained and aligned across subjects. Local volume change was then modeled in terms of diagnostic group and an interaction between group and age, adjusted for total intracranial volume, white-matter hyperintensity volume, and apolipoprotein E genotype...
November 14, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/29207392/distinct-roles-of-endothelial-dysfunction-and-inflammation-in-intracranial-atherosclerotic-stroke
#13
Jong-Won Chung, Mi Jeong Oh, Yeon Hee Cho, Gyeong Joon Moon, Gyeong-Moon Kim, Chin-Sang Chung, Kwang Ho Lee, Oh Young Bang
BACKGROUND/AIMS: The aim of the study was to evaluate the differential roles of endothelial dysfunction and inflammation in intracranial atherosclerotic stroke (ICAS). METHODS: We prospectively recruited 262 patients with acute cerebral infarcts caused by ICAS and 75 individuals with no history of stroke as controls. Markers of endothelial dysfunction (asymmetric dimethylarginine, ADMA) and inflammation (lipoprotein-associated phospholipase A2, Lp-PLA2) were measured...
2017: European Neurology
https://www.readbyqxmd.com/read/29205995/volume-and-health-outcomes-evidence-from-systematic-reviews-and-from-evaluation-of-italian-hospital-data
#14
Laura Amato, Danilo Fusco, Anna Acampora, Katia Bontempi, Alessandro Cesare Rosa, Paola Colais, Fabio Cruciani, Mariangela D'Ovidio, Francesca Mataloni, Silvia Minozzi, Zuzana Mitrova, Luigi Pinnarelli, Rosella Saulle, Salvatore Soldati, Chiara Sorge, Simona Vecchi, Martina Ventura, Marina Davoli
BACKGROUND Improving quality and effectiveness of healthcare is one of the priorities of health policies. Hospital or physician volume represents a measurable variable with an impact on effectiveness of healthcare. An Italian law calls for the definition of «qualitative, structural, technological, and quantitative standards of hospital care». There is a need for an evaluation of the available scientific evidence in order to identify qualitative, structural, technological, and quantitative standards of hospital care, including the volume of care above or below which the public and private hospitals may be accredited (or not) to provide specific healthcare interventions...
September 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/29188303/analysis-of-petrous-apex-meningocele-associated-with-meningioma-is-there-any-relation-with-chronic-intracranial-hypertension
#15
Wan-Qun Yang, Jie-Ying Feng, Hong-Jun Liu, Biao Huang, Chang-Hong Liang
PURPOSE: Petrous apex meningocele (PAM) is an uncommon cystic lesion involving the petrous apex. The underlying cause of PAM may be related to chronic elevated intracranial pressure. The aim of the study was to explore the relationship between PAM and meningioma and between PAM and other intracranial hypertension findings. METHODS: Two hundred seventy-eight consecutive patients with meningiomas were retrospectively studied. Fifty age- and gender-matched controls were also enrolled in this study...
February 2018: Neuroradiology
https://www.readbyqxmd.com/read/29170266/posttreatment-infarct-volumes-when-compared-with-24-hour-and-90-day-clinical-outcomes-insights-from-the-revascat-randomized-controlled-trial
#16
F S Al-Ajlan, A S Al Sultan, P Minhas, Z Assis, M A de Miquel, M Millán, L San Román, A Tomassello, A M Demchuk, T G Jovin, P Cuadras, A Dávalos, M Goyal, B K Menon
BACKGROUND AND PURPOSE: Endovascular therapy has become the standard of care for patients with disabling anterior circulation ischemic stroke due to proximal intracranial thrombi. Our aim was to determine whether the beneficial effect of endovascular treatment on functional outcome could be explained by a reduction in posttreatment infarct volume in the Endovascular Revascularization With Solitaire Device Versus Best Medical Therapy in Anterior Circulation Stroke Within 8 Hours (REVASCAT) trial...
November 23, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29165559/impact-of-pre-admission-oral-anticoagulation-on-ischaemic-stroke-volume-lesion-pattern-and-frequency-of-intracranial-arterial-occlusion-in-patients-with-atrial-fibrillation
#17
Joanna Dietzel, Sophie K Piper, Rudi Ruschmann, Christian Wollboldt, Tatiana Usnich, Simon Hellwig, Ivana Galinovic, Heinrich J Audebert, Matthias Endres, Kersten Villringer, Jochen B Fiebach, Karl Georg Haeusler
Aims: Therapeutic oral anticoagulation on hospital admission reduces morbidity and mortality after acute ischaemic stroke in patients with atrial fibrillation (AF). The underlying mechanism is not fully understood. In order to assess the impact of INR-level on admission on stroke volume, lesion pattern and the frequency of intracranial arterial occlusion, we analysed serial MRI measurements in AF patients suffering acute ischaemic stroke. Methods: and results This subgroup analysis of the prospective '1000Plus' study included patients with acute ischaemic stroke and known AF or a first episode of AF in hospital...
November 20, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29164237/feasibility-study-of-the-3d-visualization-at-high-resolution-of-intra-cranial-rabbit-eyes-with-x-ray-ct-phase-contrast-imaging
#18
Yury Ivanishko, Alberto Bravin, Sergey Kovalev, Polina Lisutina, Mikhail Lotoshnikov, Alberto Mittone, Sergey Tkachev, Marina Tkacheva
Purpose: The intracranial three-dimensional (3D) visualization of the whole volume of the eyeball at micrometric resolution has not been achieved yet either in clinical nor in preclinical diagnostic research. Overcoming this limitation may provide a new tool for clinical and preclinical studies of different pathologies of the various sections of the eye. The aim of this work is to give the first insight of a volumetric visualization at the high resolution of the entire enucleated and intracranial postmortem rabbit eyeballs...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29163345/fluid-distribution-pattern-in-adult-onset-congenital-idiopathic-and-secondary-normal-pressure-hydrocephalus-implications-for-clinical-care
#19
Shigeki Yamada, Masatsune Ishikawa, Kazuo Yamamoto
Objective: In spite of growing evidence of idiopathic normal-pressure hydrocephalus (NPH), a viewpoint about clinical care for idiopathic NPH is still controversial. A continuous divergence of viewpoints might be due to confusing classifications of idiopathic and adult-onset congenital NPH. To elucidate the classification of NPH, we propose that adult-onset congenital NPH should be explicitly distinguished from idiopathic and secondary NPH. Methods: On the basis of conventional CT scan or MRI, idiopathic NPH was defined as narrow sulci at the high convexity in concurrent with enlargement of the ventricles, basal cistern and Sylvian fissure, whereas adult-onset congenital NPH was defined as huge ventricles without high-convexity tightness...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29151054/effect-of-ephedrine-and-phenylephrine-on-brain-oxygenation-and-microcirculation-in-anaesthetised-patients-with-cerebral-tumours-study-protocol-for-a-randomised-controlled-trial
#20
Klaus Ulrik Koch, Anna Tietze, Joel Aanerud, Gorm von Öettingen, Niels Juul, Jens Christian Hedemann Sørensen, Lone Nikolajsen, Leif Østergaard, Mads Rasmussen
INTRODUCTION: During brain tumour surgery, vasopressor drugs are commonly administered to increase mean arterial blood pressure with the aim of maintaining sufficient cerebral perfusion pressure. Studies of the commonly used vasopressors show that brain oxygen saturation is reduced after phenylephrine administration, but unaltered by ephedrine administration. These findings may be explained by different effects of phenylephrine and ephedrine on the cerebral microcirculation, in particular the capillary transit-time heterogeneity, which determines oxygen extraction efficacy...
November 17, 2017: BMJ Open
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