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Intracranial volume measurement

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https://www.readbyqxmd.com/read/28631336/a-neuroimaging-approach-to-capture-cognitive-reserve-application-to-alzheimer-s-disease
#1
Anna C van Loenhoud, Alle Meije Wink, Colin Groot, Sander C J Verfaillie, Jos Twisk, Frederik Barkhof, Bart van Berckel, Philip Scheltens, Wiesje M van der Flier, Rik Ossenkoppele
Cognitive reserve (CR) explains interindividual differences in the ability to maintain cognitive function in the presence of neuropathology. We developed a neuroimaging approach including a measure of brain atrophy and cognition to capture this construct. In a group of 511 Alzheimer's disease (AD) biomarker-positive subjects in different stages across the disease spectrum, we performed 3T magnetic resonance imaging and predicted gray matter (GM) volume in each voxel based on cognitive performance (i.e. a global cognitive composite score), adjusted for age, sex, disease stage, premorbid brain size (i...
June 20, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28605486/aneurysm-morphology-and-prediction-of-rupture-an-international-study-of-unruptured-intracranial-aneurysms-analysis
#2
J Mocco, Robert D Brown, James C Torner, Ana W Capuano, Kyle M Fargen, Madhavan L Raghavan, David G Piepgras, Irene Meissner, John Huston Iii
BACKGROUND: There are conflicting data between natural history studies suggesting a very low risk of rupture for small, unruptured intracranial aneurysms and retrospective studies that have identified a much higher frequency of small, ruptured aneurysms than expected. OBJECTIVE: To use the prospective International Study of Unruptured Intracranial Aneurysms cohort to identify morphological characteristics predictive of unruptured intracranial aneurysm rupture. METHODS: A case-control design was used to analyze morphological characteristics associated with aneurysm rupture in the International Study of Unruptured Intracranial Aneurysms database...
June 10, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28598456/hormonal-changes-in-intracranial-hemorrhage
#3
R Shrestha, R Pradhan, M M Pradhan, C You
INTRODUCTION: The purpose of this study was to investigate the changes of serum ACTH and Thyroid hormone level in the acute phase of ICH. METHODS: Sixty patients with spontaneous ICH were assessed regarding hormonal changes by measuring ACTH and Thyroid hormone level. The relationships of hormone concentrations to clinical and radiological parameters were evaluated at hospital admission (t0), 5 days (t1) and 10 days (t2). The results were statistically analyzed...
January 2017: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/28577333/mri-based-assessment-of-acute-effect-of-head-down-tilt-position-on-intracranial-hemodynamics-and-hydrodynamics
#4
Shota Ishida, Tosiaki Miyati, Naoki Ohno, Shinnosuke Hiratsuka, Noam Alperin, Mitsuhito Mase, Toshifumi Gabata
PURPOSE: To quantify the acute effect of the head-down tilt (HDT) posture on intracranial hemodynamics and hydrodynamics. MATERIALS AND METHODS: We evaluated the intracranial physiological parameters, blood flow-related parameters, and brain morphology in the HDT (-6° and -12°) and the horizontal supine (HS) positions. Seven and 15 healthy subjects were scanned for each position using 3.0 T magnetic resonance imaging system. The peak-to-peak intracranial volume change, the peak-to-peak cerebrospinal fluid (CSF) pressure gradient (PGp-p ), and the intracranial compliance index were calculated from the blood and CSF flow determined using a cine phase-contrast technique...
June 3, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28574328/cerebrospinal-fluid-outflow-resistance-as-a-diagnostic-marker-of-spontaneous-cerebrospinal-fluid-leakage
#5
Jürgen Beck, Christian Fung, Christian T Ulrich, Michael Fiechter, Jens Fichtner, Heinrich P Mattle, Marie-Luise Mono, Niklaus Meier, Pasquale Mordasini, Werner J Z'Graggen, Jan Gralla, Andreas Raabe
OBJECTIVE Spinal CSF leakage causes spontaneous intracranial hypotension (SIH). The aim of this study was to characterize CSF dynamics via lumbar infusion testing in patients with and without proven spinal CSF leakage in order to explore possible discriminators for the presence of an open CSF leak. METHODS This analysis included all patients with suspected SIH who were treated at the authors' institution between January 2012 and February 2015. The gold standard for "proven" CSF leakage is considered to be extrathecal contrast accumulation after intrathecal contrast injection...
June 2, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28566144/the-anteroposterior-and-primary-to-posterior-limbic-ratios-as-mri-derived-volumetric-markers-of-alzheimer-s-disease
#6
Adolfo Jiménez-Huete, Susana Estévez-Santé
BACKGROUND/AIMS: Alzheimer's disease (AD) shows a characteristic pattern of brain atrophy, with predominant involvement of posterior limbic structures, and relative preservation of rostral limbic and primary cortical regions. We aimed to investigate the diagnostic utility of two gray matter volume ratios based on this pattern, and to develop a fully automated method to calculate them from unprocessed MRI files. PATIENTS AND METHODS: Cross-sectional study of 118 subjects from the ADNI database, including normal controls and patients with mild cognitive impairment (MCI) and AD...
July 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28551409/the-crumple-zone-hypothesis-association-of-frontal-sinus-volume-and-cerebral-injury-after-craniofacial-trauma
#7
Stephen S Cai, Corey Mossop, Silviu C Diaconu, David S Hersh, Sara AlFadil, Yvonne M Rasko, Michael R Christy, Michael P Granta, Arthur J Nam
PURPOSE: The paranasal sinuses are complex anatomical structures of unknown significance. One hypothesis theorizes that the sinuses, in the event of a traumatic injury, function as a crumple zone to distribute and absorb energy to protect the brain and other critical structures. The current study investigates the association between frontal sinus (FS) volume and the severity of cerebral insults following craniofacial trauma. METHODS: All patients with FS fracture admitted to a level 1 trauma center from 2011 to 2014 were retrospectively reviewed...
July 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28550246/plasma-tau-association-with-brain-atrophy-in-mild-cognitive-impairment-and-alzheimer-s-disease
#8
Kacie D Deters, Shannon L Risacher, Sungeun Kim, Kwangsik Nho, John D West, Kaj Blennow, Henrik Zetterberg, Leslie M Shaw, John Q Trojanowski, Michael W Weiner, Andrew J Saykin
BACKGROUND: Peripheral (plasma) and central (cerebrospinal fluid, CSF) measures of tau are higher in Alzheimer's disease (AD) relative to prodromal stages and controls. While elevated CSF tau concentrations have been shown to be associated with lower grey matter density (GMD) in AD-specific regions, this correlation has yet to be examined for plasma in a large study. OBJECTIVE: Determine the neuroanatomical correlates of plasma tau using voxel-based analysis. METHODS: Cross-sectional data for 508 ADNI participants were collected for clinical, plasma total-tau (t-tau), CSF amyloid (Aβ42) and tau, and MRI variables...
May 25, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28539818/isoflurane-preconditioning-inhibits-the-effects-of-tissue-type-plasminogen-activator-on-brain-endothelial-cell-in-an-in-vitro-model-of-ischemic-stroke
#9
So Yeong Cheon, So Yeon Kim, Eun Hee Kam, Jae Hoon Lee, Jeong Min Kim, Eun Jung Kim, Tae Whan Kim, Bon-Nyeo Koo
Tissue-type plasminogen activator (tPA) is the only treatment for ischemic stroke. However, tPA could induce the intracranial hemorrhage (ICH), which is the main cause of death in ischemic stroke patient after tPA treatment. At present, there is no treatment strategy to ameliorate tPA-induced brain injury after ischemia. Therefore, we investigated the effect of pre-treated isoflurane, which is a volatile anesthetic and has beneficial effects on neurological dysfunction, brain edema and infarct volume in ischemic stroke model...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28526767/migraine-and-cerebrovascular-atherosclerosis-in-patients-with-ischemic-stroke
#10
Hendrikus J A van Os, Inge A Mulder, Alexander Broersen, Ale Algra, Irene C van der Schaaf, L Jaap Kappelle, Birgitta K Velthuis, Gisela M Terwindt, Wouter J Schonewille, Marieke C Visser, Michel D Ferrari, Marianne A A van Walderveen, Marieke J H Wermer
BACKGROUND AND PURPOSE: Migraine is a well-established risk factor for ischemic stroke, but migraine is also related to other vascular diseases. This study aims to investigate the association between migraine and cerebrovascular atherosclerosis in patients with acute ischemic stroke. METHODS: We retrieved data on patients with ischemic stroke from the DUST (Dutch Acute Stroke Study). Migraine history was assessed with a migraine screener and confirmed by telephone interview based on the ICHD criteria (International Classification of Headache Disorders)...
May 19, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28514899/clinical-positioning-accuracy-for-multisession-stereotactic-radiotherapy-with-the-gamma-knife-perfexion
#11
Wade P Smith, Lori A Young, Mark H Phillips, Michael Cheung, Lia M Halasz, Jason K Rockhill
Multisession stereotactic radiation therapy is increasingly being seen as a preferred option for intracranial diseases in close proximity to critical structures and for larger target volumes. The objective of this study is to investigate the reproducibility of the Extend system from Elekta. A retrospective review was conducted for all patients treated with multisession Gamma Knife between July 2010 and June 2015, including both malignant and benign lesions. Eighty-four patients were treated in this 5-year span...
January 1, 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/28512057/normative-morphometric-data-for-cerebral-cortical-areas-over-the-lifetime-of-the-adult-human-brain
#12
Olivier Potvin, Louis Dieumegarde, Simon Duchesne
Proper normative data of anatomical measurements of cortical regions, allowing to quantify brain abnormalities, are lacking. We developed norms for regional cortical surface areas, thicknesses, and volumes based on cross-sectional MRI scans from 2713 healthy individuals aged 18 to 94 years using 23 samples provided by 21 independent research groups. The segmentation was conducted using FreeSurfer, a widely used and freely available automated segmentation software. Models predicting regional cortical estimates of each hemisphere were produced using age, sex, estimated total intracranial volume (eTIV), scanner manufacturer, magnetic field strength, and interactions as predictors...
May 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28505972/alzheimer-s-disease-associated-cerebrospinal-fluid-csf-biomarkers-do-not-correlate-with-csf-volumes-or-csf-production-rate
#13
Mikael Edsbagge, Ulf Andreasson, Khalid Ambarki, Carsten Wikkelsø, Anders Eklund, Kaj Blennow, Henrik Zetterberg, Mats Tullberg
BACKGROUND: Neuropathologically, Alzheimer's disease (AD) is characterized by accumulation of a 42 amino acid peptide called amyloid-β (Aβ42) in extracellular senile plaques together with intraneuronal inclusions of hyperphosphorylated tau protein in neurofibrillary tangles and neuronal degeneration. These changes are reflected in the cerebrospinal fluid (CSF), the volumes and production rates of which vary considerably between individuals, by reduced concentration of Aβ42, increased concentration of phosphorylated tau (P-tau) protein, and increased concentration of total tau (T-tau) protein, respectively...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28499454/risk-for-intracranial-pressure-increase-related-to-enclosed-air-in-post-craniotomy-patients-during-air-ambulance-transport-a-retrospective-cohort-study-with-simulation
#14
Helge Brändström, Anna Sundelin, Daniela Hoseason, Nina Sundström, Richard Birgander, Göran Johansson, Ola Winsö, Lars-Owe Koskinen, Michael Haney
BACKGROUND: Post-craniotomy intracranial air can be present in patients scheduled for air ambulance transport to their home hospital. We aimed to assess risk for in-flight intracranial pressure (ICP) increases related to observed intracranial air volumes, hypothetical sea level pre-transport ICP, and different potential flight levels and cabin pressures. METHODS: A cohort of consecutive subdural hematoma evacuation patients from one University Medical Centre was assessed with post-operative intracranial air volume measurements by computed tomography...
May 12, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/28492874/peripapillary-retinal-pigment-epithelium-layer-shape-changes-from-acetazolamide-treatment-in-the-idiopathic-intracranial-hypertension-treatment-trial
#15
Jui-Kai Wang, Randy H Kardon, Johannes Ledolter, Patrick A Sibony, Mark J Kupersmith, Mona K Garvin
Purpose: Recent studies indicate that the amount of deformation of the peripapillary retinal pigment epithelium and Bruch's membrane (pRPE/BM) toward or away from the vitreous may reflect acute changes in cerebrospinal fluid pressure. The study purpose is to determine if changes in optic-nerve-head (ONH) shape reflect a treatment effect (acetazolamide/placebo + weight management) using the optical coherence tomography (OCT) substudy of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) at baseline, 3, and 6 months...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28490201/a-comparison-of-haemodynamics-between-subcranial-intracranial-bypass-and-the-traditional-extracranial-intracranial-bypass
#16
Zaitao Yu, Yang Yang, Xiang'en Shi, Hai Qian, Fangjun Liu
BACKGROUND: Ischemic cerebrovascular diseases are traditionally treated using an extracranial-intracranial (EC-IC) bypass. The use of the internal maxillary artery (IMA) in the subcranial-intracranial (SC-IC) bypass was recently described as an alternative treatment. However, the haemodynamics of this new approach have not been defined. METHODS: The haemodynamic parameters (flow volume [FV], internal diameter [ID], time-averaged mean velocity [TAM], pulsatility index [PI] and resistance index [RI]) of the IMA-radial artery graft (RAG)-middle cerebral artery (MCA) (n = 12) bypass and superficial temporal artery (STA)-MCA bypass (n = 18) were measured using intraoperative duplex ultrasonography and compared...
May 11, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28486629/effect-of-caudal-block-using-different-volumes-of-local-anaesthetic-on-optic-nerve-sheath-diameter-in-children-a-prospective-randomized-trial
#17
B Lee, B-N Koo, Y S Choi, H K Kil, M-S Kim, J H Lee
Background: Caudal block is commonly administered for postoperative analgesia in children. Although caudal block with 1.5 ml kg -1 local anaesthetic has been reported to reduce cerebral oxygenation in infants, the effect of caudal block on intracranial pressure (ICP) in children has not been well investigated. Optic nerve sheath diameter (ONSD) correlates with degree of ICP. This study aimed to estimate the effects of caudal block on ICP according to volume of local anaesthetic using ultrasonographic measurement of ONSD in children...
May 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28479524/efficacy-of-arachnoid-plasty-on-chronic-subdural-hematoma-following-surgical-clipping-of-unruptured-intracranial-aneurysms
#18
Jae-Hyun Kim, Chang-Young Lee, Chang-Hyun Kim
BACKGROUND: We aimed to elucidate the effects of arachnoid plasty (ARP) on chronic subdural hematoma (CSDH) occurrence following clipping surgery. METHODS: In total 217 patients (ARP, n = 97; non-ARP, n = 120) who had undergone unruptured intracranial aneurysm (UIA) surgical clipping via the pterional approach were retrospectively assessed. Predisposing factors for CSDH development following the surgery were investigated. Thickness and volume of the subdural fluid collection (SDFC) were measured to determine whether ARP affects postoperative SDFC...
May 4, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28479474/freesurfer-cortical-normative-data-for-adults-using-desikan-killiany-tourville-and-ex-vivo-protocols
#19
Olivier Potvin, Louis Dieumegarde, Simon Duchesne
We recently built normative data for FreeSurfer morphometric estimates of cortical regions using its default atlas parcellation (Desikan-Killiany or DK) according to individual and scanner characteristics. We aimed to produced similar normative values for Desikan-Killianny-Tourville (DKT) and ex vivo-based labeling protocols, as well as examine the differences between these three atlases. Surfaces, thicknesses, and volumes of cortical regions were produced using cross-sectional magnetic resonance scans from the same 2713 healthy individuals aged 18-94 years as used in the reported DK norms...
May 4, 2017: NeuroImage
https://www.readbyqxmd.com/read/28470819/tuning-of-acurosxb-source-size-setting-for-small-intracranial-targets
#20
Stephen J Gardner, Siming Lu, Chang Liu, Ning Wen, Indrin J Chetty
This study details a method to evaluate the source size selection for small field intracranial stereotactic radiosurgery (SRS) deliveries in Eclipse treatment planning system (TPS) for AcurosXB dose calculation algorithm. Our method uses end-to-end dosimetric data to evaluate a total of five source size selections (0.50 mm, 0.75 mm, 1.00 mm, 1.25 mm, and 1.50 mm). The dosimetric leaf gap (DLG) was varied in this analysis (three DLG values were tested for each scenario). We also tested two MLC leaf designs (standard and high-definition MLC) and two delivery types for intracranial SRS (volumetric modulated arc therapy [VMAT] and dynamic conformal arc [DCA])...
May 4, 2017: Journal of Applied Clinical Medical Physics
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