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JOURNAL ARTICLE
Balaji Ganesh S, Abraham Sabu, G Kaarthikeyan, Rajalakshmanan Eswaramoorthy, Priyangha P T
PURPOSE: The study aimed to analyze whether adding Cissus quadrangularis (CQ) extract and the extracellular matrix of ovine tendon (TENDON) increases the regenerative potential of mesenchymal stem cells produced in hyaluronic acid (HA) scaffolds for tenogenesis. MATERIALS AND METHODS: Fifty grams of powdered CQ was mixed with 250 mL of ethanol to prepare the extract. Two grams of hyaluronic acid powder was added to 100 mL of distilled water to make the HA solution...
March 2024: Curēus
#22
JOURNAL ARTICLE
Dhanya Shaji, Sobha Krishnamma, Divia Attuvalappil Rajan, Subija Kunnumpurath Narayanankutty, Jinu George, Christalin Ramakrishnan
Background and objectives Direct pulp capping (dPC) is a therapeutic process that involves the application of a protective chemical to an exposed pulp with the intent to facilitate the restoration and preservation of its vitality and function. Despite numerous proposed solutions, researchers have yet to find a dependable, non-absorbable bioactive pulp capping substance that constantly activates cellular healing processes, consequently preserving pulpal vitality over an extended period of time. The objective of this study was to assess and contrast the efficacy of a novel tricalcium silicate cement and calcium hydroxide in preserving the long-term health of the dental pulp following dPC using clinical and radiographic observations...
March 2024: Curēus
#23
Lavanya S, Deepak M Ravindran, Santhanakrishnan Muthukumar, Balaji Sk, Dhanadivya Krishnakumar
An attractive smile enhances an individual's self-confidence. The overall harmony of a smile can be attributed to the interplay of the teeth's shape, color, and position along with the gingival tissue. Gingival pigmentation is observed across all human races, exhibiting variations from one race to another. Typically, gingival hyperpigmentation results from the abnormal buildup of melanin in the gingival tissue, imparting a dark appearance on the gums. Various procedures, collectively known as gingival depigmentation, are employed to address gingival hyperpigmentation...
March 2024: Curēus
#24
REVIEW
Babitha Merin George, Siddarth Arya, Shwetha G S, Keerthana Bharadwaj, Vaishnavi N S
Malocclusion is a widespread oral health issue that adversely affects individuals' health and well-being. Currently, fixed orthodontics is considered the most efficient treatment for correcting malocclusion, with archwire bending playing a key role in orthodontic treatment. Traditionally, orthodontists manually performed archwire bending using various handheld pliers and other mechanical tools, requiring a significant amount of time, precision, and specialized training yet being unable to guarantee appliance accuracy...
March 2024: Curēus
#25
JOURNAL ARTICLE
Induja M, Roland Prethipa, Lokesh Kumar S, Rajalakshmanan Eswaramoorthy, Jayanth Kumar Vadivel
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a global health concern associated with systemic as well as oral complications. The preventive antioxidants found in saliva naturally reduce the damaging effects of reactive oxygen molecules. Any disruption to the regular functioning of these antioxidants may lead to oxidative stress, which could boost an individual's vulnerability to oral diseases. Diabetes patients are vulnerable to various dental complications, such as oral mucosal disorders, dental caries, dry mouth, and periodontal disease...
March 2024: Curēus
#26
REVIEW
Nusaibah S Nordin, Haslina Taib
Oral health's impact on overall well-being highlights the importance of preventive measures through effective oral hygiene practices. Currently, there is growing recognition of the need for customized oral hygiene advice depending on the patient's unique needs and circumstances. This narrative review addresses the gap in understanding the significance of personalized guidance through the proposal of the Personalized Oral Hygiene Advice Model (POHAM) as a comprehensive guide for oral health professionals. This model was developed to adapt to evolving patient demographics and diverse challenges, promoting a patient-centric and effective oral health approach...
March 2024: Curēus
#27
JOURNAL ARTICLE
Minxuan Lan, Eric Niu, Meirong Liu, Sadiyah Anderson, LaToya Barham, Tanya Greenfield, Gail Cherry-Peppers, Xinbin Gu
Oral health plays a crucial role in overall well-being. One of the goals set by the US Department of Health and Human Service, Healthy People 2030 is to reducing dental caries in children and adolescents. The study aims to investigate the accessibility of pediatric dental care in neighborhoods with mixed-race and predominantly African American populations in the Washington District of Columbia (DC) area. Our objective is to uncover and highlight the disparities that exist in pediatric dental care within these communities...
2024: Dent Res Oral Health
#28
JOURNAL ARTICLE
Clara Isabel Anton Y Otero, Laurine Marger, Enrico di Bella, Albert Feilzer, Ivo Krejci, Marwa Abdelaziz
OBJECTIVE: To evaluate the penetration of a dye in root dentin after activation with different laser wavelengths. MATERIALS: Palatal roots of 38 human molars were enlarged and disinfected. Irrigation activation was performed with an Er:YAG laser: @50 mJ, 15 Hz (Er:YAG); a 9.3 µm CO2 laser: @40% power (CO2 ); diode lasers 455 nm/970 nm: @0.8 W, 15 Hz (D455, D970) and 808/980 nm: @1 W (D808, D980) and compared to positive control: etching with 35% H3 PO4 (POS); negative control: water (NEG) and conventional needle irrigation: NaOCl and ethylenediaminetetraacetic acid (EDTA) (CONV)...
2024: Biomaterial investigations in dentistry
#29
REVIEW
Mohammed A Hadis, Adrian C Shortall, William M Palin
Harnessing the power of light and its photonic energy is a powerful tool in biomedical applications. Its use ranges from biomaterials processing and fabrication of polymers to diagnostics and therapeutics. Dental light curable materials have evolved over several decades and now offer very fast (≤ 10 s) and reliable polymerization through depth (4-6 mm thick). This has been achieved by developments on two fronts: (1) chemistries with more efficient light absorption characteristics (camphorquinone [CQ], ~30 L mol-1 cm1 [ʎmax 470 nm]; monoacylphosphine oxides [MAPO], ~800 L mol-1 cm-1 [ʎmax 385 nm]; bisacylphosphine oxide [BAPO], ~1,000 L mol-1 cm-1 [ʎmax 385 nm]) as well mechanistically efficient and prolonged radical generation processes during and after light irradiation, and; (2) introducing light curing technologies (light emitting diodes [LEDs] and less common lasers) with higher powers (≤ 2 W), better spectral range using multiple diodes (short: 390-405 nm; intermediate: 410-450 nm; and long: 450-480 nm), and better spatial power distribution (i...
2024: Biomaterial investigations in dentistry
#30
JOURNAL ARTICLE
Siqun Xu, Jieya Wei, Jing Xie
Lipid droplets are dynamic multifunctional organelles composed of a neutral lipid core and a phospholipid monolayer membrane modified by a specific set of proteins. PAT family proteins are the most characteristic lipid droplet proteins, playing an important role in regulating lipid droplet structure, function, and metabolism. The biogenesis of lipid droplets involves neutral lipid synthesis and the nucleation, budding, and growth of the lipid droplets. Lipid droplets not only serve as the energy metabolism reserve of cells but also participate in intracellular signal transduction and the development of inflammation and tumor...
March 20, 2024: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
#31
JOURNAL ARTICLE
Sreekumar Saranya, Chandrashekar Janakiram, Anil Mathew
PURPOSE: Primary dental care facilities and awareness about temporomandibular disorders are lacking among the indigenous population of Kerala. The aim of the study was to determine the prevalence of temporomandibular joint dysfunction (TMD) disorders among the indigenous populations of Kerala. METHODOLOGY: This cross-sectional study included adults aged 18 years and above, visiting primary health care centre in the tribal hamlet in the town of Kalpetta, Wayanad District, Kerala, India, for reasons other than dental...
2024: Journal of Oral Biology and Craniofacial Research
#32
REVIEW
Isha Duggal, Tulika Tripathi
In the current technological era, dental practitioners are faced with various ethical challenges, highlighting the importance of bioethics in this healthcare discipline. The rise of artificial intelligence has recently sparked a debate regarding the privacy of patient data. While the advancements may offer innovative treatment options, their long-term effects may not be fully understood, raising questions about the responsible implementation of such methods. Thus, conscientious and ethical AI use in dentistry encompasses that patients be notified about how their data is used and also about the involvement of AI-based decision-making...
2024: Journal of Oral Biology and Craniofacial Research
#33
JOURNAL ARTICLE
Carolina R Le-Bert, Alex Bukoski, John Downs, David S Hodgson, Lori Thombs, Sam H Ridgway, James Bailey
INTRODUCTION: Use of mechanical ventilation during general anesthesia is a necessary practice in the anesthetization of small cetaceans as spontaneous ventilation fails to provide adequate gas exchange. Currently available methods of ventilation do not account for the intermittent breathing strategy of representative species within this infraorder of fully aquatic mammals and may have a significant effect on cardiac and respiratory physiology. METHODS: To understand the impact of mechanical ventilation on cardiopulmonary function in one small species of cetacean, the bottlenose dolphin ( Tursiops truncatus ), we compared controlled mechanical ventilation (CMV) to a novel ventilation method known as apneustic anesthesia ventilation (AAV)...
2024: Frontiers in Veterinary Science
#34
JOURNAL ARTICLE
Hoda Amani Hamedani, Thomas Stegall, Yi Yang, Haochen Wang, Ashwin Menon, Anubhuti Bhalotia, Efstathios Karathanasis, Jeffrey R Capadona, Allison Hess-Dunning
ABSTRACT: The current work presents a novel flexible multifunctional platform for biological interface applications. The use of titania nanotube arrays (TNAs) as a multifunctional material is explored for soft-tissue interface applications. In vitro biocompatibility of TNAs to brain-derived cells was first examined by culturing microglia cells-the resident immune cells of the central nervous system on the surface of TNAs. The release profile of an anti-inflammatory drug, dexamethasone from TNAs-on-polyimide substrates, was then evaluated under different bending modes...
2024: MRS Bulletin
#35
Haeseong Lee, Bach Le, Parish Sedghizadeh
Dens evaginatus (DE) presents a clinical conundrum due to its fragility and propensity to cause pulpal and periapical complications. Clinicians should heed the presence of DE during clinical examinations and avoid unnecessary intervention.
April 2024: Clinical Case Reports
#36
JOURNAL ARTICLE
Balgis Gaffar, Robert J Schroth, Morẹ Nikẹ Oluwátóyìn Foláyan, Francisco Ramos-Gomez, Jorma I Virtanen
BACKGROUND: There is no accessible information on countries with oral health policies. The purpose of this study was to identify World Dental Federation (FDI) member countries with oral health policies and their scope and extent of coverage of oral health care for young children. METHODS: This international survey recruited chief dental officers, oral health advisors to national ministries of health, and other key informants of the 158 FDI member countries between December 2020 and December 2021...
2024: Front Oral Health
#37
JOURNAL ARTICLE
Pavel Seredin, Dmitry Goloshchapov, Anna Emelyanova, Konstantin Eremeev, Yaroslav Peshkov, Khidmet Shikhaliev, Andrey Potapov, Yury Ippolitov, Vladimir Kashkarov, Dmitry Nesterov, Kirill Shapiro, Raul O Freitas, Iman A Mahdy
In this work, we developed a technology that enables rapid deposition of biomimetic composite films onto natural enamel slices (known as biotemplates). These films are composed of polydopamine (PDA) and nanocrystalline carbonate-substituted hydroxyapatite (nano-cHAp) that have been functionalized with amino acid l-Arginine. We utilized atomic force microscopy (AFM) and scattering scanning near-field optical microscopy (s-SNOM) combined with infrared (IR) synchrotron to achieve nanoscale spatial resolution for both IR absorption and topography analyses...
April 16, 2024: ACS Omega
#38
Mark Cannon, Elizabeth Dempsey, Ashlee Cosantino, Navdeep Chandel, Nayereh Ghoreishi-Haack
Background: This study aimed to evaluate the effects of continuous administration of xylitol (a commonly used dental prebiotic) via a subcutaneous osmotic minipump in a B16F10 syngeneic mouse model. Methods: The B16F10 syngeneic model consisted of 6-8-week-old C57BL/6 male mice subcutaneously injected with five × 10 5 B16F10 cells suspended in 100 μl PBS in the right flank. The mice were randomly assigned to two groups: Group 1 was the treatment group with 10% xylitol-loaded pumps (n=10), while Group 2 was the control group with saline-loaded pumps (n=10)...
April 2, 2024: Research Square
#39
Amy C Moreno, Erin E Watson, Laia Humbert-Vidan, Douglas E Peterson, Lisanne V van Dijk, Teresa Guerrero Urbano, Lisa Van den Bosch, Andrew J Hope, Matthew S Katz, Frank J P Hoebers, Ruth A Aponte Wesson, James E Bates, Paolo Bossi, Adeyinka F Dayo, Mélanie Doré, Eduardo Rodrigues Fregnani, Thomas J Galloway, Daphna Y Gelblum, Issa A Hanna, Christina E Henson, Sudarat Kiat-Amnuay, Anke Korfage, Nancy Y Lee, Carol M Lewis, Charlotte Duch Lynggaard, Antti A Mäkitie, Marco Magalhaes, Yvonne M Mowery, Carles Muñoz-Montplet, Jeffrey N Myers, Ester Orlandi, Jaymit Patel, Jillian M Rigert, Deborah Saunders, Jonathan D Schoenfeld, Ugur Selek, Efsun Somay, Vinita Takiar, Juliette Thariat, Gerda M Verduijn, Alessandro Villa, Nick West, Max J H Witjes, Alex Won, Mark E Wong, Christopher M K L Yao, Simon W Young, Kamal Al-Eryani, Carly E A Barbon, Doke J M Buurman, François J Dieleman, Theresa M Hofstede, Abdul Ahad Khan, Adegbenga O Otun, John C Robinson, Lauren Hum, Jorgen Johansen, Rajesh Lalla, Alexander Lin, Vinod Patel, Richard J Shaw, Mark S Chambers, Daniel Ma, Mabi Singh, Noam Yarom, Abdallah Sherif Radwan Mohamed, Katherine A Hutcheson, Stephen Y Lai, Clifton David Fuller
PURPOSE: Osteoradionecrosis of the jaw (ORNJ) is a severe iatrogenic disease characterized by bone death after radiation therapy (RT) to the head and neck. With over 9 published definitions and at least 16 diagnostic/staging systems, the true incidence and severity of ORNJ are obscured by lack of a standard for disease definition and severity assessment, leading to inaccurate estimation of incidence, reporting ambiguity, and likely under-diagnosis worldwide. This study aimed to achieve consensus on an explicit definition and phenotype of ORNJ and related precursor states through data standardization to facilitate effective diagnosis, monitoring, and multidisciplinary management of ORNJ...
April 9, 2024: medRxiv
#40
JOURNAL ARTICLE
Saskia T M Ammer, Nathan Routhledge, Gareth R Davies, Arian C van Asten, Suzan J A Verdegaal-Warmerdam, Lisette M Kootker
The determination of an individual's geographic origin is an essential aspect of forensic investigations. When primary identifiers cannot be used to make a positive identification, isotope analysis can be utilized to provide new leads. Modern reference data are essential for accurate interpretation of human isotopic data in terms of diet and origin. This article presents Sr-O-C-N-H isotope data of modern individuals (hair, dental enamel, and dentine collagen) and drinking water from the Netherlands. The δ 15 N values of human hair fall within the range of values observed worldwide and cannot be utilized to differentiate from other countries...
April 19, 2024: IScience
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