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https://www.readbyqxmd.com/read/27876592/sirs-qsofa-and-organ-dysfunction-insights-from-a-prospective-database-of-emergency-department-patients-with-infection
#1
Julian M Williams, Jaimi H Greenslade, Juliet V McKenzie, Kevin Chu, Anthony Ft Brown, Jeffrey Lipman
OBJECTIVE: A proposed revision of sepsis definitions has abandoned SIRS, defined organ dysfunction as an increase in total SOFA score of ≥2, and conceived "qSOFA" as a bedside indicator of organ dysfunction. We aimed to (1) determine the prognostic impact of SIRS, (2) compare diagnostic accuracy of SIRS and qSOFA for organ dysfunction, and (3) compare standard (Sepsis-2) and revised (Sepsis-3) definitions for organ dysfunction in emergency department patients with infection. METHODS: Consecutive ED patients admitted with presumed infection were prospectively enrolled over three years...
November 19, 2016: Chest
https://www.readbyqxmd.com/read/27856268/validation-of-the-new-sepsis-3-definitions-proposal-for-improvement-in-early-risk-identification
#2
Evangelos J Giamarellos-Bourboulis, Thomas Tsaganos, Iraklis Tsangaris, Malvina Lada, Christina Routsi, Dimitrios Sinapidis, Marina Koupetori, Magdalini Bristianou, George Adamis, Konstantinos Mandragos, George N Dalekos, Ioannis Kritselis, George Giannikopoulos, Ioannis Koutelidakis, Maria Pavlaki, Eleni Antoniadou, Glykeria Vlachogiannis, Vasilios Koulouras, Athanassios Prekates, George Dimopoulos, Antonia Koutsoukou, Ioannis Pnevmatikos, Aikaterini Ioakeimidou, Anastasia Kotanidou, Stylianos E Orfanos, Apostolos Armaganidis, Charalambos Gogos
OBJECTIVES: Sepsis-3 definitions generated controversies regarding their general applicability. The Sepsis-3 Task Force outscored the need of validation with emphasis on quick SOFA (qSOFA) score. This was done in a prospective cohort coming from a different health-care setting. METHODS: Patients with infections and at least two signs of the systemic inflammatory response syndrome (SIRS) were analyzed. Sepsis was defined as total SOFA ≥2 outside the ICU or as increase of ICU admission SOFA ≥2...
November 14, 2016: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/27851145/1509-ed-qsofa-score-a-simple-predictor-for-adverse-outcomes-following-admission-for-blunt-trauma
#3
Randeep Jawa, James Vosswinkel, Jane McCormack, Emily Huang, Henry Thode, Marc Shapiro, Adam Singer
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851128/1492-the-validation-of-qsofa-criteria-for-sepsis
#4
Michihito Kyo, Shinichiro Ohshimo, Yoshiko Kida, Nobuaki Shime
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851116/1480-assessing-qsofa-scores-in-non-icu-hospitalized-patients
#5
Daleen Penoyer, Patricia Geddie, Jessica Snyder
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851092/1456-a-comparison-of-sofa-using-spo2-fio2-ratio-to-sofa-sirs-and-qsofa-for-sepsis-mortality
#6
Faheem Guirgis, Sarah Sterling, Carmen Smotherman, Frederick Moore, Alan Jones
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851074/1438-early-determination-of-outcomes-for-sirs-vs-qsofa-in-ed-sepsis-patients
#7
Dave Milzman, Matthew Paik, Kirsten Shuster, Rand Floyd, Aidan Neustadtl, Rob Haggerty, Shawn Haupt, Doug Johnson
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851050/1414-prospective-validation-of-qsofa-in-emergency-services-a-useless-bedside-clinical-score
#8
Fabian Jaimes, Alba Leon, Johana Ascuntar, Cesar Niño, Jessica Londoño, Maribel Plaza, Pablo Castaño, Carolina Hincapie
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851017/1381-evaluation-of-the-qsofa-score-in-the-emergency-department
#9
Sarah Cogle, Amber Hutchison, Haley Bennett, Darrell Childress
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851000/1364-comparison-of-the-qsofa-score-and-sirs-criteria-in-patients-with-known-or-suspected-sepsis
#10
James Gasperino, Evangeline Gabriel-Jocson, Erik Perez, Ronni Levy, Luciano Lemos-Filho
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27850989/1353-sepsis-clinical-criteria-in-ed-patients-admitted-to-an-icu-an-external-validation-study-of-qsofa
#11
James Lantry, Michael April
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27850981/1345-serial-evaluation-of-qsofa-among-patients-with-suspected-infection
#12
Daniel Kievlan, Li Ang Zhang, Joyce Chung-Chou Chang, Jeremy Kahn, Derek Angus, Christopher Seymour
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27850973/1337-clinical-application-of-the-qsofa-in-icu-patients-with-bacteremia-a-single-center-study-in-korea
#13
Hae Jung Na, Kwangha Lee, Eun Suk Jeong, Insu Kim, Ki Uk Kim, Hye-Kyung Park, Min Ki Lee, Tae Hwa Kim
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27850967/1331-assessment-of-qsofa-and-other-criteria-in-sepsis-with-normal-blood-pressure-and-intermediate-lactate
#14
Jan Kasal, Barry Stoll, Anup Katyal, David Tannehill, Jackyln O'Brien, Upagya Kompalli, Sanjay Subramanian
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27850963/1327-qsofa-criteria-predicts-clinical-outcomes-of-hospitalized-emergency-department-pneumonia-patients
#15
Kemba Mark, Naomi George, Hasan Rasheed, David Meurer, Brandon Allen, Marie-Carmelle Elie-Turenne, Peter Hou, Raghu Seethala
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27849937/295-qsofa-is-an-acceptable-bedside-tool-to-predict-adverse-events-within-24-hrs-following-met-activation
#16
Hwan Il Kim, Dae-Sang Lee, Yong Dae Lee, Chi Ryang Chung, Jeong Hoon Yang, Kyeongman Jeon, Chi-Min Park, Gee Young Suh
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27849699/19-external-validation-of-the-qsofa-criteria-in-a-multicenter-emergency-department-cohort
#17
Naomi George, Hasan Rasheed, David Meurer, Brandon Allen, Raghu Seethala, Mark Kemba, Peter Hou, Marie-Carmelle Elie-Turenne
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27829179/combining-quick-sequential-organ-failure-assessment-with-plasma-lactate-concentration-is-comparable-to-standard-sequential-organ-failure-assessment-score-in-predicting-mortality-of-patients-with-and-without-suspected-infection
#18
Kwok M Ho, Norris S H Lan
PURPOSE: We sought to determine whether quick Sequential Organ Failure Assessment (qSOFA) score can be used to predict mortality of patients without suspected infection. MATERIALS AND METHODS: Using prospectively collected data within the first hour of intensive care unit admission, the predictive ability of qSOFA was compared with the Simplified Acute Physiology Score III, Admission Mortality Prediction Model III, Acute Physiology and Chronic Health Evaluation II model, and standard (full-version) SOFA score using area under the receiver operating characteristic (AUROC) curve and Brier score...
October 18, 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/27823893/sepsis-clinical-criteria-in-emergency-department-patients-admitted-to-an-intensive-care-unit-an-external-validation-study-of-quick-sequential-organ-failure-assessment
#19
Michael D April, Jose Aguirre, Lloyd I Tannenbaum, Tyler Moore, Alexander Pingree, Robert E Thaxton, Daniel J Sessions, James H Lantry
BACKGROUND: Quick Sequential Organ Failure Assessment (qSOFA) is a prognostic score for patients with sepsis. OBJECTIVE: Our aim was to compare the area under the receiver operating curve (AUROC), sensitivity, specificity, and likelihood ratios of qSOFA vs. systemic inflammation response syndrome (SIRS) in predicting in-hospital mortality among emergency department (ED) patients with suspected infection admitted to intensive care units (ICUs). METHODS: We conducted a retrospective cohort chart review study of ED patients admitted to an ICU with suspected infection from August 1, 2012 to February 28, 2015...
November 4, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27694098/prediction-of-sepsis-in-the-intensive-care-unit-with-minimal-electronic-health-record-data-a-machine-learning-approach
#20
Thomas Desautels, Jacob Calvert, Jana Hoffman, Melissa Jay, Yaniv Kerem, Lisa Shieh, David Shimabukuro, Uli Chettipally, Mitchell D Feldman, Chris Barton, David J Wales, Ritankar Das
BACKGROUND: Sepsis is one of the leading causes of mortality in hospitalized patients. Despite this fact, a reliable means of predicting sepsis onset remains elusive. Early and accurate sepsis onset predictions could allow more aggressive and targeted therapy while maintaining antimicrobial stewardship. Existing detection methods suffer from low performance and often require time-consuming laboratory test results. OBJECTIVE: To study and validate a sepsis prediction method, InSight, for the new Sepsis-3 definitions in retrospective data, make predictions using a minimal set of variables from within the electronic health record data, compare the performance of this approach with existing scoring systems, and investigate the effects of data sparsity on InSight performance...
September 30, 2016: JMIR Medical Informatics
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