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https://www.readbyqxmd.com/read/30025372/mica-129-a-g-dimorphism-its-relation-to-soluble-mica-plasma-level-and-spontaneous-preterm-birth-a-case-control-study
#1
Renate Von Linsingen, Geórgia Fernanda Gelmini, Maria da Graça Bicalho, Newton Sérgio De Carvalho
The aim of this case- control study was to investigate the association between preterm birth (PTB), MICA-129 A/G dimorphism and sMICA levels. Fifty pregnant women with singleton pregnancy and previous PTB, or clinic diagnostic of threatened preterm labor in the actual pregnancy, or cervical length less than 25 mm and 50 healthy pregnant women were enrolled. DNA was extracted for genotyping for MICA-129 A/G by real-time PCR and sMICA plasma level was quantified by sandwich ELISA assay. Clinical and socioeconomic characteristics, results of TaqMan® genotyping and ELISA quantification were compared between the groups using qui-square, Fisher´s exact or Mann-Whitney test...
July 10, 2018: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/30010181/rapid-cervical-phigfbp-1-test-in-asymptomatic-twin-pregnancies-is-inefficient-in-predicting-preterm-delivery-prior-to-34-gestational-weeks
#2
Katarzyna Kosińska-Kaczyńska, Iwona Szymusik, Dorota Bomba-Opoń, Aleksandra Zyguła, Mirosław Wielgoś
OBJECTIVES: To assess the effectiveness of a rapid second trimester test for cervical phIGFBP-1 in the prediction of sponta-neous preterm delivery prior to 34 weeks in asymptomatic twin pregnancies. MATERIAL AND METHODS: A prospective observational study conducted on 232 twin pregnancies tested for phIGFBP-1 at 20-24 weeks of gestation. 151 patients assessed as asymptomatic, with cervical length > 25 mm at 20-24 weeks were analysed. The primary outcome was the delivery < 34 weeks of gestation...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/29983643/cost-effectiveness-of-diagnostic-tests-for-threatened-preterm-labor-in-singleton-pregnancy-in-france
#3
Thomas Desplanches, Catherine Lejeune, Jonathan Cottenet, Paul Sagot, Catherine Quantin
Background: Previous studies have showed that the early diagnosis of threatened preterm labor decreases neonatal morbidity and mortality, avoids maternal morbidity induced by antepartum bed rest and unnecessary treatment, and reduces costs. Although there are many diagnostic tests, none is clearly recommended by international guidelines. The aim of our study was to compare seven diagnostic methods in terms of effectiveness and cost using a decision analysis model in singleton pregnancy presenting threatened preterm labor, between 24 and 34 weeks of gestation...
2018: Cost Effectiveness and Resource Allocation: C/E
https://www.readbyqxmd.com/read/29962517/controversies-about-the-secondary-prevention-of-spontaneous-preterm-birth
#4
Ioannis Kyvernitakis, Holger Maul, Franz Bahlmann
Preterm birth is one of the major global health problems and part of the Millennium Development goals because of the associated high number of perinatal or neonatal mortality and long-term risks of neurodevelopmental and metabolic diseases. Transvaginal sonography has meanwhile been established as a screening tool for spontaneous preterm birth despite its relatively low sensitivity when considering only the cervical length. Vaginal progesterone has been shown to reduce prematurity rates below 34 weeks in a screening population of singleton pregnancies...
June 2018: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/29945711/does-progesterone-prophylaxis-to-prevent-preterm-labour-improve-outcome-a-randomised-double-blind-placebo-controlled-trial-opptimum
#5
Jane E Norman, Neil Marlow, Claudia-Martina Messow, Andrew Shennan, Philip R Bennett, Steven Thornton, Stephen C Robson, Alex McConnachie, Stavros Petrou, Neil J Sebire, Tina Lavender, Sonia Whyte, John Norrie
BACKGROUND: Progesterone prophylaxis is widely used to prevent preterm birth but is not licensed and there is little information on long-term outcome. OBJECTIVE: To determine the effect of progesterone prophylaxis in women at high risk of preterm birth on obstetric, neonatal and childhood outcomes. DESIGN: Double-blind, randomised placebo-controlled trial. SETTING: Obstetric units in the UK and Europe between February 2009 and April 2013...
June 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29909269/can-uterocervical-angles-successfully-predict-induction-of-labor-in-nulliparous-women
#6
Emrah Dagdeviren, Berna Aslan Çetin, Begum Aydogan Mathyk, Nadiye Koroglu, Elif Goknur Topcu, Mehmet Aytac Yuksel
PURPOSE: Induction of labor is a common practice in obstetrics. In recent years, a newer ultrasonographic parameter called the uterocervical angle (UCA) has been identified as a predictive tool for births. Our purpose is to investigate the role of UCA in predicting successful induction of labor. METHODS: The nulliparous term pregnancies (n:150) were grouped into successful/failed inductions of labor based on their progress into the active phase of labor after the administration of prostaglandin E2 (dinoprostone)...
June 11, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29889906/quantitative-assessment-of-physical-activity-in-pregnant-women-with-sonographic-short-cervix-and-the-risk-for-preterm-delivery-a-prospective-pilot-study
#7
Roni Zemet, Eyal Schiff, Zipora Manovitch, Tal Cahan, Rakefet Yoeli-Ullman, Benny Brandt, Israel Hendler, Lilia Dorfman-Margolis, Yoav Yinon, Eyal Sivan, Shali Mazaki-Tovi
OBJECTIVE: Bed rest or activity restriction is a common obstetrical practice, despite a paucity of data to support its efficacy. The aim of this study was to determine whether physical activity, as assessed by a smart band activity tracker, is associated with preterm birth in pregnant women at high risk for preterm delivery. METHODS: This was a pilot prospective cohort study including pregnant women at high risk for preterm delivery between 24 and 32 weeks-of-gestation...
2018: PloS One
https://www.readbyqxmd.com/read/29889763/using-cervical-length-measurement-for-lower-spontaneous-preterm-birth-rates-among-women-with-threatened-preterm-labor
#8
Giuseppe Chiossi, George R Saade, Baha Sibai, Vincenzo Berghella
Spontaneous preterm birth is a leading cause of perinatal morbidity and mortality; however, accurate identification of women who will deliver prematurely after the onset of uterine contractions is still challenging, because less than 10% actually give birth within 7 days of presentation. Risk stratification in women with preterm contractions would allow targeting of interventions such as corticosteroids, magnesium sulfate, and maternal transfer to a perinatal center to those who will indeed deliver preterm...
July 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29880174/neutrophil-elastase-in-cervical-fluid-in-women-with-short-cervical-length
#9
Soo Ran Choi, Soon-Sun Hong, Juyoung Kim, Keun-Young Lee
OBJECTIVE: The aim of the study was to determine the relationships between short cervical length (CL) and levels of cervical fluid neutrophil elastase (NE), secretory leukocyte protease inhibitor (SLPI), and interleukin 8 (IL-8) in the second trimester of pregnancy of women who underwent ultrasound-indicated cervical cerclage. MATERIALS AND METHODS: CL of <25 mm or cervical funneling were included in the short CL group (n = 26) and the normal CL group (n = 22) included women who had CL of ≥25 mm and had no cervical funneling in women between 17 + 0 and 24 + 6 weeks of gestation...
June 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29880168/amniotic-fluid-index-single-deepest-pocket-and-transvaginal-cervical-length-parameter-of-predictive-delivery-latency-in-preterm-premature-rupture-of-membranes
#10
Young-Joo Lee, Seung-Chul Kim, Jong-Kil Joo, Dong-Hyung Lee, Ki-Hyung Kim, Kyu-Sup Lee
OBJECTIVE: Prediction of delivery latency complicated with preterm premature rupture of membrane (PPROM) is crucial for reducing maternal and neonatal complications. Therefore, we investigated the correlations between latency period and cut-off values of ultrasonographic parameters, ultimately predicting delivery latency. MATERIALS AND METHODS: The retrospective study was performed on 121 PPROM patients enrolled between March 2010 and July 2015. Parameters including amniotic fluid index (AFI), single deepest pocket (SDP) and transvaginal cervical length (TVCL) were measured in 99 singleton pregnancies with PPROM...
June 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29843547/prediction-of-spontaneous-preterm-birth-salivary-progesterone-assay-and-transvaginal-cervical-length-assessment-after-24-weeks-of-gestation-another-critical-window-of-opportunity
#11
Wessam M Abuelghar, Mohamed I Ellaithy, Khaled H Swidan, Ihab S Allam, Heba M Haggag
OBJECTIVES: Measurement of salivary progesterone (SP4) levels and cervical length (CL) after 24 weeks to assess their potential predictive value among asymptomatic women at high risk of spontaneous preterm birth (PTB). METHODS: This prospective observational (noninterventional) study consecutively recruited asymptomatic women at high risk of spontaneous PTB. SP4 and CL were measured at recruitment (24-28 weeks of gestation) then repeated after 3-4 weeks. All recruited women were followed up regularly till delivery...
June 25, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29813033/a-soft-cervix-categorized-by-shear-wave-elastography-in-women-with-short-or-with-normal-cervical-length-at-18-24-weeks-is-associated-with-a-higher-prevalence-of-spontaneous-preterm-delivery
#12
Edgar Hernandez-Andrade, Eli Maymon, Suchaya Luewan, Gaurav Bhatti, Mohammad Mehrmohammadi, Offer Erez, Percy Pacora, Bogdan Done, Sonia S Hassan, Roberto Romero
OBJECTIVE: To determine whether a soft cervix identified by shear-wave elastography between 18 and 24 weeks of gestation is associated with increased frequency of spontaneous preterm delivery (sPTD). MATERIALS AND METHODS: This prospective cohort study included 628 consecutive women with a singleton pregnancy. Cervical length (mm) and softness [shear-wave speed: (SWS) meters per second (m/s)] of the internal cervical os were measured at 18-24 weeks of gestation...
July 26, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29804334/-prevention-of-preterm-birth-in-twins-with-short-mid-trimester-cervical-length-less-than-25mm-combined-treatment-with-arabin-s-cerclage-pessary-and-intravaginal-micronized-progesterone-compared-with-conservative-treatment
#13
Ariel Zimerman, Ron Maymon, Yfat Viner, Noa Glick, Arie Herman, Ortal Neeman
BACKGROUND: Twin pregnancies with short mid-trimester cervical length have a high rate of preterm births. OBJECTIVES: To compare combined treatment of Arabin cerclage pessary, and intravaginal micronized progesterone to conservative treatment for the prevention of preterm births in twins pregnancies with short cervical length in second trimester of pregnancy. METHODS: A retrospective study that compared twin pregnancies with short ≤25mm cervix in second trimester 16-28 gestational weeks treated with combined treatment of Arabin cervical pessary and intravaginal micronized progesterone 200mg TID to a control group with conservative treatment for the prevention of preterm...
May 2018: Harefuah
https://www.readbyqxmd.com/read/29792058/utilization-of-progesterone-and-cervical-length-screening-for-prevention-of-recurrent-preterm-birth
#14
Rupsa C Boelig, Eva Jiang, Brooke Scheidemantle, Michela Villani, Vincenzo Berghella
OBJECTIVE: To assess utilization of progesterone and cervical length (CL) screening among women with prior spontaneous preterm birth (sPTB). METHODS: This is a retrospective cohort study of women with prior sPTB. Primary outcomes were the use of progesterone and CL screening. Secondary outcomes were reasons for failure to utilize interventions and factors associated with use of recommended interventions. RESULTS: 180 women had a prior sPTB...
June 17, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29772945/the-efficiency-of-the-uterocervical-angle-in-the-prediction-of-second-trimester-pregnancy-terminations-in-multiparous-women
#15
Berna Aslan Cetin, Begum Aydogan Mathyk, Nadiye Koroglu, Gozde Demirezen, Gokce Turan, Gokhan Demirayak, Gokhan Yildirim
AIM: To show how uterocervical angles are used for the prediction of second-trimester pregnancy terminations in multiparous women. MATERIAL AND METHODS: A total of 148 multiparous singleton women in their second trimesters were enrolled in this prospective study. The intracervical Foley catheter was used for the induction of delivery. The cervical length (CL) and the uterocervical angle (UCA) were measured before the beginning of induction. The study population was subdivided into four groups; successful and failed terminations at the end of 24 and 48 h time frames...
May 17, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29764255/knot-positioning-during-mcdonald-cervical-cerclage-does-it-make-a-difference-a-cohort-study
#16
Hytham Atia, Mohamed Ellaithy, Ahmed Altraigey, Heba Ibrahim
OBJECTIVE: To study the effect of McDonald cerclage knot position on the different maternal and neonatal outcomes. METHODS: This historical cohort study included women with singleton pregnancy who had a prophylactic McDonald cervical cerclage between 1 May 2010 and 31 September 2017. Maternal and neonatal outcome parameters were compared between the anterior and posterior knot cerclage procedures. The primary outcome measure was the rate of term birth. RESULTS: 550 Women had a prophylactic McDonald cervical cerclage, 306 with anterior knot (Group A) and 244 with posterior knot (Group B)...
May 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29761527/a-quality-study-to-explore-rationale-for-pregnant-women-to-decline-transvaginal-cervical-length-screening
#17
Matthew Keller, Adriane Burgess, James Hole, Margaret Warren, Jessica Burkindine, Mary Jo Johnson
OBJECTIVES: To identify patient rationale for pregnant women to decline transvaginal cervical length screening. METHODS: Survey data from 511 women presenting for second-trimester anatomy and transvaginal cervical length sonography were collected during a 4-month period from September 2016 to January 2017. Each patient completed a medical questionnaire that includes demographic and obstetric history data and a survey to document their acceptance or declination of transvaginal cervical length screening...
May 15, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29743041/plasma-inflammatory-and-immune-proteins-as-predictors-of-intra-amniotic-infection-and-spontaneous-preterm-delivery-in-women-with-preterm-labor-a-retrospective-study
#18
Hyunsoo Park, Kyo Hoon Park, Yu Mi Kim, Song Yi Kook, Se Jeong Jeon, Ha-Na Yoo
BACKGROUND: We investigated whether various inflammatory and immune proteins in plasma predict intra-amniotic infection and imminent preterm delivery in women with preterm labor and compared their predictive ability with that of amniotic fluid (AF) interleukin (IL)-6 and serum C-reactive protein (CRP). METHODS: This retrospective cohort study included 173 consecutive women with preterm labor who underwent amniocentesis for diagnosis of infection and/or inflammation in the AF...
May 9, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29727248/quantitative-fetal-fibronectin-and-cervical-length-in-symptomatic-women-results-from-a-prospective-blinded-cohort-study
#19
Lisa D Levine, Katheryne L Downes, Julie A Romero, Hope Pappas, Michal A Elovitz
OBJECTIVES: Our objectives were to determine whether quantitative fetal fibronectin (fFN) and cervical length (CL) screening can be used alone or in combination as prognostic tests to identify symptomatic women at the highest or lowest risk for spontaneous preterm birth (sPTB). METHODS: A prospective, blinded cohort study of women presenting with a singleton gestation to our triage unit between 22-33w6d with preterm labor symptoms was performed. Women with ruptured membranes, moderate/severe bleeding, and dilation >2 cm were excluded...
May 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29715336/incorrect-cervical-length-category-definitions
#20
(no author information available yet)
No abstract text is available yet for this article.
May 1, 2018: JAMA: the Journal of the American Medical Association
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