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https://www.readbyqxmd.com/read/30240653/prediction-of-spontaneous-preterm-delivery-in-women-presenting-with-premature-labor-a-comparison-of-placenta-alpha-microglobulin-1-phosphorylated-insulin-like-growth-factor-binding-protein-1-and-cervical-length
#1
Tanja Nikolova, Jukka Uotila, Natasha Nikolova, Vyacheslav M Bolotskikh, Vera Y Borisova, Gian Carlo di Renzo
BACKGROUND: Placental alpha microglobulin-1 (PAMG-1) and phosphorylated insulin-like growth factor-binding protein-1 (phIGFBP-1) have been studied in patients at risk for preterm birth with signs and symptoms of preterm labor. However, a direct comparison between these two biomarkers, alone or in combination with cervical length measurement with an adequate sample size, has been lacking to date. OBJECTIVE: To compare PAMG-1 test and the phIGFBP-1-1 test alone and in combination with cervical length measurement for the prediction of imminent spontaneous preterm birth of testing in pregnant women with symptoms of preterm labor in a tertiary care setting...
September 18, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30237138/vaginal-progesterone-for-the-prevention-of-preterm-birth-and-the-risk-of-gestational-diabetes
#2
Yaniv Zipori, Roy Lauterbach, Emad Matanes, Ron Beloosesky, Zeev Weiner, Amir Weissman
INTRODUCTION: We aimed to determine whether daily vaginal progesterone use for the prevention of preterm birth has an effect on the incidence of abnormal glucose challenge test or gestational diabetes. STUDY DESIGN: A retrospective study in a large referral center. Women with cervical length ≤ 25 mm were given 200 mg vaginal micronized progesterone capsules daily at bed time until 36 weeks` gestation or delivery. Each progesterone-treated woman was matched randomly with three untreated controls...
September 11, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30225687/is-vaginal-progesterone-treatment-associated-with-the-development-of-gestational-diabetes-a-retrospective-case-control-study
#3
Klara Rosta, Johannes Ott, Fanni Kelemen, Wilhelm Temsch, Tobias Lahner, Theresa Reischer, Hanns Helmer, Aniko Somogyi
PURPOSE: To determine the incidence of gestational diabetes mellitus (GDM) in pregnant women who received vaginal progesterone due to short cervical length or to prevent recurrent preterm birth. METHODS: In this retrospective study, we included 190 women with singleton pregnancies at risk for preterm birth who received vaginal natural progesterone (200 mg daily between gestational weeks 16 + 0 and 36 + 0) for a minimum of 4 weeks and delivered > 28 weeks...
September 17, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/30218572/plasma-progesterone-estradiol-and-unconjugated-estriol-concentrations-in-twin-pregnancies-relation-to-cervical-length-and-preterm-delivery
#4
Vilma L Johnsson, Nina G Pedersen, Katharina Worda, Elisabeth Krampl-Bettelheim, Lilian Skibsted, Stefan Hinterberger, Isolde Strobl, Maria E Bowman, Roger Smith, Ann Tabor, Line Rode
INTRODUCTION: The aim was to examine the association between plasma hormone concentrations, cervical length and preterm delivery in twin pregnancies, including the effect of progesterone treatment. MATERIAL AND METHODS: This study included 191 women with a twin gestation from a randomized placebo-controlled trial. A baseline blood sample was collected at 18-24 weeks before treatment with vaginal progesterone (n=95) or placebo pessaries (n=96), and 167 (87.4%) women had a second sample collected after 4-8 weeks of treatment...
September 15, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/30198351/intraobserver-and-interobserver-variability-in-first-trimester-transvaginal-ultrasound-cervical-length
#5
Andrea Gascón, Maria Goya, Manel Mendoza, Anna Garcia, Teresa Higueras, Inés Calero, Mayte Avilés, Mª Angeles Sánchez, Elisa Llurba, Luis Cabero, Elena Carreras
OBJECTIVES: To determine intraobserver and interobserver variability in the measurement of different cervical length (CL) components at the first trimester (endocervical canal and isthmus), describe the optimum measurement method (single line or two lines) and establish a normality curve of first trimester CL in our population. METHODS: Women who attended the first-trimester US scan, between 11.0 and 13.6 weeks of gestation at Vall d'Hebron Universitary Hospital, Barcelona, Spain were included...
September 9, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30196741/outcome-after-fetoscopic-laser-coagulation-in-twin-twin-transfusion-syndrome-is-the-survival-rate-of-at-least-one-child-at-6-months-of-age-dependent-on-preoperative-cervical-length-and-preterm-prelabour-rupture-of-fetal-membranes
#6
Ladina Rüegg, Margaret Hüsler, Franziska Krähenmann, Giancarlo Natalucci, Roland Zimmermann, Nicole Ochsenbein-Kölble
PURPOSE: Twin-to-twin transfusion syndrome (TTTS) complicates 10-15% of all monochorionic twin pregnancies. Selective laser coagulation of placental anastomoses is the only causal therapy. The aim of this study was to analyze the neonatal survival, the survival rate of at least one child at 6 months of age, and maternal outcome after laser therapy in a Swiss cohort. MATERIAL AND METHODS: Between 2008 and 2014, 39 women were treated with fetoscopic laser procedure due to TTTS...
September 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30176754/comparison-of-reliability-between-uterocervical-angle-and-cervical-length-measurements-by-various-experienced-operators-using-transvaginal-ultrasound
#7
Ninlapa Pruksanusak, Rapphon Sawaddisan, Ounjai Kor-Anantakul, Thitima Suntharasaj, Chitkasaem Suwanrath, Alan Geater
OBJECTIVE: To compare the reliability between uterocervical angle (UCA) and cervical length (CL) measurements by various experienced operators. METHODS: Transvaginal ultrasonographies (TVS) were performed in 102 pregnant women between 160/7 -240/7 gestational weeks by different levels of experienced operators. For both CL and UCA measurements, intraobserver variability was assessed for each operators by examining the range between maximum and minimum measurements in each participants, compared to the mean of all three measurements...
September 3, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30173089/effects-of-exercise-during-pregnancy-in-women-with-short-cervix-secondary-analysis-from-the-italian-pessary-trial-in-singletons
#8
Gabriele Saccone, Vincenzo Berghella, Roberta Venturella, Pietro D'Alessandro, Bruno Arduino, Antonio Raffone, Antonia Giudicepietro, Silvia Visentin, Amerigo Vitagliano, Pasquale Martinelli, Fulvio Zullo
OBJECTIVE: To evaluate effects of exercise during pregnancy in asymptomatic singleton pregnancies without prior spontaneous preterm birth (SPTB) but with short transvaginal ultrasound cervical length (TVU CL). STUDY DESIGN: This is a secondary analysis of the Italian Pessary Trial for the Italian Preterm Birth Prevention (IPP) Working Group. In the original prospective randomized controlled trial asymptomatic singleton pregnancies without prior SPTB but with TVU CL ≤ 25 mm at 18 0/6-23 6/7 weeks were randomized into 1:1 ratio to either cervical pessary or no pessary...
August 28, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30157678/cervical-length-cut-off-for-preterm-birth-prediction-in-twins-let-s-use-fifth-percentile
#9
Giovanni Sisti, Mariarosaria Di Tommaso
No abstract text is available yet for this article.
August 29, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30149206/development-of-a-nomogram-for-individual-preterm-birth-risk-evaluation
#10
Mélanie Korsakissok, Marion Groussolles, Odile Dicky, Corinne Alberge, Charlotte Casper, Corinne Azogui-Assouline
OBJECTIVE: This study aimed to develop a new tool for personalised preterm birth risk evaluation in high-risk population. STUDY DESIGN: 813 high-risk asymptomatic pregnant women included in a French multicentric prospective study were analysed. Clinical and paraclinical variables, including screening for bacterial vaginosis with molecular biology and cervical length, have been used to create the nomogram, based on the logistic regression model. The validity was checked by bootstrap...
August 24, 2018: Journal of Gynecology Obstetrics and Human Reproduction
https://www.readbyqxmd.com/read/30144728/risk-factors-for-coexistence-of-cervical-elongation-in-uterine-prolapse
#11
Sheng-Mou Hsiao, Ting-Chen Chang, Chi-Hau Chen, Yu-I Li, Chia-Tung Shun, Ho-Hsiung Lin
OBJECTIVE: To identify factors predicting cervical elongation in women with uterine prolapse. STUDY DESIGN: The medical records of women with uterine prolapse who underwent vaginal hysterectomy were reviewed. Multivariable logistic regression analysis was performed to identify predictors of cervical elongation. RESULTS: Of 295 women with uterine prolapse, 136 (46.1%) patients had cervical elongation, according to Berger et al. Classification (i...
August 8, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30140107/rescue-adjuvant-vaginal-progesterone-may-improve-outcomes-in-cervical-cerclage-failure
#12
Alina R Roman, Fabricio Da Silva Costa, Edward Araujo Júnior, Penelope M Sheehan
Introduction Aim of the study was to evaluate the effect of rescue adjuvant vaginal progesterone in women with ongoing, transvaginal ultrasound (TVUS)-confirmed cervical shortening despite cervical cerclage. Materials and Methods A retrospective case control study was performed of women undergoing cervical surveillance following either history- or ultrasound-indicated cervical cerclage. We compared women managed with cervical cerclage and vaginal progesterone to women managed with cervical cerclage alone. Women with a singleton pregnancy who underwent cervical cerclage were identified from a database...
August 2018: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/30112757/cervical-cerclage-versus-vaginal-progesterone-for-management-of-short-cervix-in-low-risk-women
#13
Amber M Wood, Sarah K Dotters-Katz, Brenna L Hughes
OBJECTIVE:  To evaluate the risk of preterm birth in low-risk women with cervical length (CL) ≤25 mm on transvaginal ultrasound (TVUS) managed with vaginal progesterone (VagP) therapy versus cerclage. STUDY DESIGN:  This is a retrospective cohort of women with no prior history of preterm birth or cervical insufficiency and CL ≤ 25 mm on TVUS, managed with either VagP therapy alone or cerclage (with or without VagP). The primary outcome was rate of preterm delivery < 37 weeks gestational age (GA)...
August 15, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/30107361/midtrimester-transvaginal-ultrasound-cervical-length-screening-for-spontaneous-preterm-birth-in-diamniotic-twin-pregnancies-according-to-chorionicity
#14
Amanda Roman, Gabriele Saccone, Carolynn M Dude, Andrew Ward, Hannah Anastasio, Lorraine Dugoff, Fulvio Zullo, Vincenzo Berghella
OBJECTIVE: To compare the mean transvaginal ultrasound (TVU) cervical length (CL) at midtrimester screening for spontaneous preterm birth in asymptomatic monochorionic diamniotic versus dichorionic diamniotic twin pregnancies STUDY DESIGN: This was a multicenter retrospective cohort study. Study subjects were identified at the time of a routine second trimester fetal ultrasound exam at 18 0/7-23 6/7 weeks gestation. We excluded women that received progesterone, pessary, or cerclage. Distribution of CL was determined and normality was examined...
August 8, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30102606/vasa-previa-prenatal-diagnosis-and-management
#15
Yaakov Melcer, Ron Maymon, Eric Jauniaux
PURPOSE OF REVIEW: Vasa previa is a rare disorder of placentation associated with a high rate of perinatal morbidity and mortality when undetected before delivery. We have evaluated the recent evidence for prenatal diagnosis and management of vasa previa. RECENT FINDINGS: Around 85% of cases of vasa previa have one or more identifiable risk factors including in-vitro fertilization, multiple gestations, bilobed, succenturiate or low-lying placentas, and velamentous cord insertion...
August 9, 2018: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/30099822/mri-measurement-of-residual-cervical-length-after-radical-trachelectomy-for-cervical-cancer-and-the-risk-of-adverse-pregnancy-outcomes-a-blinded-imaging-analysis
#16
Rosa M Alvarez, Ioannis Biliatis, Andrea Rockall, Eleni Papadakou, S Aslam Sohaib, Nandita M deSouza, John Butler, Marielle Nobbenhuis, Desmond J P Barton, John H Shepherd, Thomas E J Ind
OBJECTIVE: To determine the association between the residual cervix measured on post-operative MRI after radical vaginal trachelectomy (RVT) and adverse obstetric outcomes. DESIGN: Observational study. SETTING: Referral Cancer centre. POPULATION: Women who conceived after RVT for cervical cancer at the Royal Marsden Hospital, London, between 1995 and 2015. METHODS: Post-operative MRI scans were analysed by three researchers...
August 12, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/30095769/cervical-pessary-after-arrested-preterm-labor-a-randomized-controlled-trial
#17
Frederik J R Hermans, Ewoud Schuit, Mireille N Bekker, Mallory Woiski, Marjon A de Boer, Marieke Sueters, Hubertina C J Scheepers, Maureen T M Franssen, Eva Pajkrt, Ben Willem J Mol, Marjolein Kok
OBJECTIVE: To assess the effectiveness of cervical pessary in reducing the rate of preterm birth in women at high risk for preterm birth who did not deliver after an episode of threatened preterm labor. METHODS: In a multicenter open-label randomized controlled trial, a cervical pessary was compared with no intervention (control group) (one-to-one ratio). Women between 24 and 34 weeks of gestation at high risk for preterm birth based on a short cervical length (less than 15 mm) or an intermediate cervical length (between 15 and 30 mm) with a positive fetal fibronectin test who did not deliver after an episode of threatened preterm labor were eligible...
September 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30081692/the-presence-of-amniotic-fluid-sludge-in-pregnant-women-with-a-short-cervix-an-independent-risk-of-preterm-delivery
#18
Youhei Tsunoda, Takehiko Fukami, Koichi Yoneyama, Ikuno Kawabata, Toshiyuki Takeshita
OBJECTIVE: To examine whether the presence of amniotic fluid sludge (AFS) could increase the risk of preterm delivery in women with a cervical length of less than 25 mm. MATERIALS AND METHODS: This is a retrospective cohort study of 110 women who were 14-30 weeks pregnant with a singleton gestation and a cervical length of less than 25 mm. The primary outcomes were defined as preterm delivery before 34 weeks and preterm delivery before 37 weeks. The secondary outcome was defined as preterm premature rupture of membranes (PPROM) prior to preterm delivery...
August 6, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30052338/conservative-management-of-huge-symptomatic-endocervical-polyp-in-pregnancy-a-case-report
#19
Sameer Hamadeh, Bishr Addas, Nasreen Hamadeh, Jessica Rahman
Cervical polyp is very rare in pregnancy, usually asymptomatic and small. There are several reports of different sizes of cervical polyp in pregnancy but, huge cervical polyp causing funnelling and shortening of cervical length was first reported in 2014. It was managed by polypectomy causing cervical length to return to normal value. We present the second case report in literature of a huge endocervical polyp in pregnancy that caused funnelling and shortening of cervical length. Unlike the earlier report this patient presented with preterm contractions and antepartum haemorrhage (APH)...
June 2018: African Journal of Reproductive Health
https://www.readbyqxmd.com/read/30049238/maternal-body-mass-index-and-cervical-length-among-women-with-a-history-of-spontaneous-preterm-birth-%C3%A2
#20
Kartik K Venkatesh, Tracy A Manuck
OBJECTIVES: To evaluate whether women with a prior spontaneous preterm birth (SPTB) with a higher body mass index (BMI) have a lower risk of a shortened cervix in a subsequent pregnancy. STUDY DESIGN: A secondary analysis of the Maternal-Fetal Medicine Units Network RCT of omega-3 fatty acid supplementation for recurrent SPTB prevention. All women had ≥1 prior SPTB <37 weeks, a singleton pregnancy, and initiated 17-alpha hydroxyprogesterone caproate(17-OHPC)...
September 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
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