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https://www.readbyqxmd.com/read/28737470/recent-advances-in-circulating-tumor-cells-and-cell-free-dna-in-metastatic-prostate-cancer-a-review
#1
Sunil Parimi, Jenny J Ko
The treatment landscape of metastatic prostate cancer has changed dramatically over the past five years. As new discoveries are made and further novel therapies become available, there is a heightened urgency to develop biomarkers that can guide prognoses and predict therapy responses. Circulating tumor cells (CTCs) and cell-free circulating tumor DNA (ctDNA) in the blood have emerged as potential promising tumor avatars. Areas covered: In this review, we describe technological breakthroughs and clinical implementation of the CTCs and ctDNA...
July 24, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28736940/seven-year-olds-aggressive-choices-in-a-computer-game-can-be-predicted-in-infancy
#2
Dale F Hay, Mark K Johansen, Peter Daly, Salim Hashmi, Charlotte Robinson, Stephan Collishaw, Stephanie van Goozen
Concerns about the relationship between computer games and children's aggression have been expressed for decades, but it is not yet clear whether the content of such games evokes aggression or a prior history of aggression promotes children's interest in aggressive games. Two hundred and sixty-six 7-year-old children from a nationally representative longitudinal sample in the UK played a novel computer game (CAMGAME) in which the child's avatar encountered a series of social challenges that might evoke aggressive, prosocial or neutral behaviour...
July 24, 2017: Developmental Science
https://www.readbyqxmd.com/read/28732534/information-sought-information-shared-exploring-performance-and-image-enhancing-drug-user-facilitated-harm-reduction-information-in-online-forums
#3
Boden Tighe, Matthew Dunn, Fiona H McKay, Timothy Piatkowski
BACKGROUND: There is good evidence to suggest that performance and image enhancing drug (PIED) use is increasing in Australia and that there is an increase in those using PIEDs who have never used another illicit substance. Peers have always been an important source of information in this group, though the rise of the Internet, and the increased use of Internet forums amongst substance consumers to share harm reduction information, means that PIED users may have access to a large array of views and opinions...
July 21, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28727884/oct-angiography-and-ellipsoid-zone-mapping-of-macular-telangiectasia-type-2-from-the-avatar-study
#4
Anne P Runkle, Peter K Kaiser, Sunil K Srivastava, Andrew P Schachat, Jamie L Reese, Justis P Ehlers
Purpose: To evaluate alterations on optical coherence tomography angiography (OCT-A) and quantitatively assess alterations in the ellipsoid zone (EZ) in eyes with macular telangiectasia type 2 (MacTel type 2). Methods: The Observational Assessment of Visualizing and Analyzing Vessels With Optical Coherence Tomography Angiography in Retinal Diseases study is an institutional review board-approved prospective, observational study investigating OCT-A in macular disease...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28706725/avatars-and-virtual-agents-relationship-interfaces-for-the-elderly
#5
REVIEW
Nava A Shaked
In the Digital Era, the authors witness a change in the relationship between the patient and the care-giver or Health Maintenance Organization's providing the health services. Another fact is the use of various technologies to increase the effectiveness and quality of health services across all primary and secondary users. These technologies range from telemedicine systems, decision making tools, online and self-services applications and virtual agents; all providing information and assistance. The common thread between all these digital implementations, is they all require human machine interfaces...
June 2017: Healthcare Technology Letters
https://www.readbyqxmd.com/read/28705358/the-status-value-of-age
#6
Christopher P Kelley, Shane D Soboroff, Michael J Lovaglia
A controlled experiment and three replications examined the relationship between a person's age as a status characteristic and the value placed on that person as a potential group member. The experiments used computer-generated avatars to isolate the effects of age on the status value of partners being chosen for a work-related task. The design allowed us to compare the effect of age on status for members of three distinct groups: younger adults, middle-aged adults, and much older adults. Results showed that undergraduate participants rated middle-aged adult avatars higher on status indicators and chose to work with middle-aged adult avatars significantly more often than younger adult or much older adult avatars...
August 2017: Social Science Research
https://www.readbyqxmd.com/read/28695664/managing-fall-armyworm-spodoptera-frugiperda-lepidoptera-noctuidae-with-bt-maize-and-insecticides-in-south-brazil
#7
Leonardo M Burtet, Oderlei Bernardi, Adriano A Melo, Maiquel P Pes, Thiago T Strahl, Jerson Vc Guedes
BACKGROUND: Maize plants expressing insecticidal proteins of Bacillus thuringiensis are valuable options for managing fall armyworm (FAW), Spodoptera frugiperda, in Brazil. However, control failures were reported, and therefore insecticides have been used to control this species. Based on these, we evaluated Bt maize and its integration with insecticides against FAW in south Brazil. RESULTS: Early-planted Agrisure TL, Herculex, Optimum Intrasect and non-Bt maize plants were severely damaged by FAW and required up to three insecticidal sprays...
July 11, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28692837/influence-of-gait-mode-and-body-orientation-on-following-a-walking-avatar
#8
L Rens A Meerhoff, Harjo J de Poel, Tim W D Jowett, Chris Button
Regulating distance with a moving object or person is a key component of human movement and of skillful interpersonal coordination. The current set of experiments aimed to assess the role of gait mode and body orientation on distance regulation using a cyclical locomotor tracking task in which participants followed a virtual leader. In the first experiment, participants moved in the backward-forward direction while the body orientation of the virtual leader was manipulated (i.e., facing towards, or away from the follower), hence imposing an incongruence in gait mode between leader and follower...
July 7, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28647565/review-of-the-cytology-and-connections-of-the-lateral-habenula-an-avatar-of-adaptive-behaving
#9
REVIEW
Daniel S Zahm, David H Root
The cytology and connections of the lateral habenula (LHb) are reviewed. The habenula is first introduced, after which the cytology of the LHb is discussed mainly with reference to cell types, general topography and descriptions of subnuclei. An overview of LHb afferent connections is given followed by some details about the projections to LHb from a number of structures. An overview of lateral habenula efferent connections is given followed by some details about the projections from LHb to a number of structures...
June 21, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28639206/are-associations-between-sexist-video-games-and-decreased-empathy-toward-women-robust-a-reanalysis-of-gabbiadini-et-al-2016
#10
Christopher J Ferguson, M Brent Donnellan
Gabbiadini, A., Riva, P., Andrighetto, L., Volpato, C., & Bushman, B, (PloS ONE, 2016) provided evidence for a connection between "sexist" video games and decreased empathy toward girls using an experimental paradigm. These claims are based on a moderated mediation model. They reported a three-way interaction between game condition, gender, and avatar identification when predicting masculine ideology in their original study. Masculine ideology was associated, in turn, with decreased empathy. However, there were no main experimental effects for video game condition on empathy...
June 21, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28635345/avatar-assisted-therapy-a-proof-of-concept-pilot-study-of-a-novel-technology-based-intervention-to-treat-substance-use-disorders
#11
Michael S Gordon, Steven B Carswell, Mary Schadegg, Kayla Mangen, Kelly Merkel, Susan Tangires, Frank J Vocci
BACKGROUND: Avatar-assisted therapy (AAT) is a novel and emerging technology that uses the Internet to enable clinicians and clients in substance abuse treatment to participate in group counseling sessions from separate and remote locations in real time through the use of avatars and virtual environments. OBJECTIVES: The current study is a pilot proof-of-concept feasibility study involving individuals in outpatient substance abuse treatment. This report addresses two questions: (1) are individuals who present for substance abuse treatment interested in receiving AAT and (2) what factors are associated with better treatment success...
September 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28600704/steering-clear-of-driving-after-drinking-a-tailored-e-health-intervention-for-reducing-repeat-offending-and-modifying-alcohol-use-in-a-high-risk-cohort
#12
Hollie Jai Wilson, Gavan Palk, Mary Christina Sheehan, Darren Wishart, Barry Watson
PURPOSE: Digital interventions to reduce risk behaviours are emerging as effective public health measures; however, few have been applied to drink driving and associated alcohol use based on a harm reduction perspective. This paper reports on the design, development, and pilot of a novel intervention which aims to reduce repeat offending by first-time convicted drink driving offenders. It explores whether an online program is acceptable and user friendly and contains useful and relevant content, with a sample of first-time drink driving offenders recruited at the time of conviction...
June 9, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28595055/the-body-model-theory-of-somatosensory-cortex
#13
REVIEW
Michael Brecht
I outline a microcircuit theory of somatosensory cortex as a body model serving both for body representation and "body simulation." A modular model of innervated and non-innervated body parts resides in somatosensory cortical layer 4. This body model is continuously updated and compares to an avatar (an animatable puppet) rather than a mere sensory map. Superficial layers provide context and store sensory memories, whereas layer 5 provides motor output and stores motor memories. I predict that layer-6-to-layer-4 inputs initiate body simulations allowing rehearsal and risk assessment of difficult actions, such as jumps...
June 7, 2017: Neuron
https://www.readbyqxmd.com/read/28592282/the-role-of-virtual-reality-in-improving-motor-performance-as-revealed-by-eeg-a-randomized-clinical-trial
#14
Rocco Salvatore Calabrò, Antonino Naro, Margherita Russo, Antonino Leo, Rosaria De Luca, Tina Balletta, Antonio Buda, Gianluca La Rosa, Alessia Bramanti, Placido Bramanti
BACKGROUND: Many studies have demonstrated the usefulness of repetitive task practice by using robotic-assisted gait training (RAGT) devices, including Lokomat, for the treatment of lower limb paresis. Virtual reality (VR) has proved to be a valuable tool to improve neurorehabilitation training. The aim of our pilot randomized clinical trial was to understand the neurophysiological basis of motor function recovery induced by the association between RAGT (by using Lokomat device) and VR (an animated avatar in a 2D VR) by studying electroencephalographic (EEG) oscillations...
June 7, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28578296/attentional-interference-is-modulated-by-salience-not-sentience
#15
Christopher J Wilson, Alessandro Soranzo, Marco Bertamini
Spatial cueing of attention occurs when attention is oriented by the onset of a stimulus or by other information that creates a bias towards a particular location. The presence of a cue that orients attention can also interfere with participants' reporting of what they see. It has been suggested that this type of interference is stronger in the presence of socially-relevant cues, such as human faces or avatars, and is therefore indicative of a specialised role for perspective calculation within the social domain...
July 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28560254/unravelling-socio-motor-biomarkers-in-schizophrenia
#16
Piotr Słowiński, Francesco Alderisio, Chao Zhai, Yuan Shen, Peter Tino, Catherine Bortolon, Delphine Capdevielle, Laura Cohen, Mahdi Khoramshahi, Aude Billard, Robin Salesse, Mathieu Gueugnon, Ludovic Marin, Benoit G Bardy, Mario di Bernardo, Stephane Raffard, Krasimira Tsaneva-Atanasova
We present novel, low-cost and non-invasive potential diagnostic biomarkers of schizophrenia. They are based on the 'mirror-game', a coordination task in which two partners are asked to mimic each other's hand movements. In particular, we use the patient's solo movement, recorded in the absence of a partner, and motion recorded during interaction with an artificial agent, a computer avatar or a humanoid robot. In order to discriminate between the patients and controls, we employ statistical learning techniques, which we apply to nonverbal synchrony and neuromotor features derived from the participants' movement data...
2017: NPJ Schizophrenia
https://www.readbyqxmd.com/read/28550447/trends-in-surgical-research-in-head-and-neck-cancer
#17
REVIEW
Genrich Tolstonog, Christian Simon
The task of surgical research is to improve the efficacy of available surgical therapeutic modalities, develop new ones, and balance this well with favorable functional outcome. Therefore, surgical research is composed of a translational and a clinical component. In translational surgical research, animal models are used to better understand the biology of head and neck cancers, but even more importantly, the biology of changes to the disease and the microenvironment created by surgical interventions. Animal models additionally allow for the development of image-guided surgery systems, novel strategies of intraoperative adjuvant treatment, and patient "avatars" to test innovative anticancer drug combinations...
June 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/28506312/pathomimetic-avatars-reveal-divergent-roles-of-microenvironment-in-invasive-transition-of-ductal-carcinoma-in-situ
#18
Mansoureh Sameni, Dora Cavallo-Medved, Omar E Franco, Anita Chalasani, Kyungmin Ji, Neha Aggarwal, Arulselvi Anbalagan, Xuequn Chen, Raymond R Mattingly, Simon W Hayward, Bonnie F Sloane
BACKGROUND: The breast tumor microenvironment regulates progression of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC). However, it is unclear how interactions between breast epithelial and stromal cells can drive this progression and whether there are reliable microenvironmental biomarkers to predict transition of DCIS to IDC. METHODS: We used xenograft mouse models and a 3D pathomimetic model termed mammary architecture and microenvironment engineering (MAME) to study the interplay between human breast myoepithelial cells (MEPs) and cancer-associated fibroblasts (CAFs) on DCIS progression...
May 15, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28501698/sensorimotor-experience-in-virtual-reality-enhances-sense-of-agency-associated-with-an-avatar
#19
Gaiqing Kong, Kang He, Kunlin Wei
No abstract text is available yet for this article.
May 11, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28498339/easy-and-fast-reconstruction-of-a-3d-avatar-with-an-rgb-d-sensor
#20
Aihua Mao, Hong Zhang, Yuxin Liu, Yinglong Zheng, Guiqing Li, Guoqiang Han
This paper proposes a new easy and fast 3D avatar reconstruction method using an RGB-D sensor. Users can easily implement human body scanning and modeling just with a personal computer and a single RGB-D sensor such as a Microsoft Kinect within a small workspace in their home or office. To make the reconstruction of 3D avatars easy and fast, a new data capture strategy is proposed for efficient human body scanning, which captures only 18 frames from six views with a close scanning distance to fully cover the body; meanwhile, efficient alignment algorithms are presented to locally align the data frames in the single view and then globally align them in multi-views based on pairwise correspondence...
May 12, 2017: Sensors
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