keyword
https://read.qxmd.com/read/38536186/quality-of-life-after-axillary-lymph-node-dissection-among-racial-and-ethnic-minority-women
#1
JOURNAL ARTICLE
Danielle R Heller, Bayley Axelrod, Varadan Sevilimedu, Monica Morrow, Babak J Mehrara, Andrea V Barrio
IMPORTANCE: Higher lymphedema rates after axillary lymph node dissection (ALND) have been found in Black and Hispanic women; however, there is poor correlation between subjective symptoms, quality of life (QOL), and measured lymphedema. Additionally, racial and ethnic differences in QOL have been understudied. OBJECTIVE: To evaluate the association of race and ethnicity with long-term QOL in patients with breast cancer treated with ALND. DESIGN, SETTING, AND PARTICIPANTS: This cohort study enrolled women aged 18 years and older with breast cancer who underwent unilateral ALND at a tertiary cancer center between November 2016 and March 2020...
March 27, 2024: JAMA Surgery
https://read.qxmd.com/read/38523227/aso-visual-abstract-remote-symptom-monitoring-with-clinical-alerts-following-mastectomy-do-early-symptoms-predict%C3%A2-30-day-surgical%C3%A2-complications
#2
JOURNAL ARTICLE
Jacqueline J Chu, Audree B Tadros, Perri S Vingan, Melissa J Assel, Taylor M McCready, Andrew J Vickers, Sigrid Carlsson, Monica Morrow, Babak J Mehrara, Carrie S Stern, Andrea L Pusic, Jonas A Nelson
No abstract text is available yet for this article.
March 24, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38442245/endemic-coronavirus-infections-are-associated-with-strong-homotypic-immunity-in-a-us-cohort-of-children-from-birth-to-4-years
#3
JOURNAL ARTICLE
Ardythe L Morrow, Daniel C Payne, Shannon C Conrey, Meredith McMorrow, Monica M McNeal, Liang Niu, Allison R Burrell, Elizabeth P Schlaudecker, Claire Mattison, Rachel M Burke, Emily DeFranco, Zheyi Teoh, Jens Wrammert, Lydia J Atherton, Natalie J Thornburg, Mary A Staat
BACKGROUND: The endemic coronaviruses OC43, HKU1, NL63 and 229E cause cold-like symptoms and are related to SARS-CoV-2, but their natural histories are poorly understood. In a cohort of children followed from birth to 4 years, we documented all coronavirus infections, including SARS-CoV-2, to understand protection against subsequent infections with the same virus (homotypic immunity) or a different coronavirus (heterotypic immunity). METHODS: Mother-child pairs were enrolled in metropolitan Cincinnati during the third trimester of pregnancy in 2017-18...
March 5, 2024: Journal of the Pediatric Infectious Diseases Society
https://read.qxmd.com/read/38366142/factors-associated-with-prolonged-respiratory-virus-detection-from-pcr-of-nasal-specimens-collected-longitudinally-in-healthy-children-in-a-u-s-birth-cohort
#4
JOURNAL ARTICLE
Zheyi Teoh, Shannon Conrey, Monica McNeal, Allison Burrell, Rachel M Burke, Claire P Mattison, Meredith McMorrow, Natalie Thornburg, Daniel C Payne, Ardythe L Morrow, Mary Allen Staat
BACKGROUND: Respiratory viral shedding is incompletely characterized by existing studies due to the lack of longitudinal nasal sampling and limited inclusion of healthy/asymptomatic children. We describe characteristics associated with prolonged virus detection by PCR in a community-based birth cohort. METHODS: Children were followed from birth to 2 years of age in the PREVAIL cohort. Weekly nasal swabs were collected and tested using the Luminex Respiratory Pathogen Panel...
February 15, 2024: Journal of the Pediatric Infectious Diseases Society
https://read.qxmd.com/read/38355780/remote-symptom-monitoring-with-clinical-alerts-following-mastectomy-do-early-symptoms-predict-30-day-surgical-complications
#5
JOURNAL ARTICLE
Jacqueline J Chu, Audree B Tadros, Perri S Vingan, Melissa J Assel, Taylor M McCready, Andrew J Vickers, Sigrid Carlsson, Monica Morrow, Babak J Mehrara, Carrie S Stern, Andrea L Pusic, Jonas A Nelson
BACKGROUND: Electronic patient-reported outcome measures (ePROMs) for real-time remote symptom monitoring facilitate early recognition of postoperative complications. We sought to determine whether remote, electronic, patient-reported symptom-monitoring with Recovery Tracker predicts 30-day readmission or reoperation in outpatient mastectomy patients. METHODS: We conducted a retrospective review of breast cancer patients who underwent outpatient (< 24-h stay) mastectomy with or without reconstruction from April 2017 to January 2022 and who received the Recovery Tracker on Days 1-10 postoperatively...
February 14, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38330312/correlates-of-rotavirus-vaccine-shedding-and-seroconversion-in-a-u-s-cohort-of-healthy-infants
#6
JOURNAL ARTICLE
Rachel M Burke, Daniel C Payne, Monica McNeal, Shannon C Conrey, Allison R Burrell, Claire P Mattison, Mary C Casey-Moore, Slavica Mijatovic-Rustempasic, Rashi Gautam, Mathew D Esona, Alexander W Thorman, Michael D Bowen, Umesh D Parashar, Jacqueline E Tate, Ardythe L Morrow, Mary A Staat
BACKGROUND: Rotavirus is a leading cause of severe pediatric gastroenteritis; two highly effective vaccines are used in the US. We aimed to identify correlates of immune response to rotavirus vaccination in a US cohort. METHODS: PREVAIL is a birth cohort of 245 mother-child pairs enrolled 2017-2018 and followed for 2 years. Infant stool samples and symptom information were collected weekly. Shedding was defined as RT-PCR detection of rotavirus vaccine virus in stools collected 4-28 days after dose one...
February 8, 2024: Journal of Infectious Diseases
https://read.qxmd.com/read/38231509/robotic-nipple-sparing-mastectomy-ready-for-prime-time
#7
JOURNAL ARTICLE
Monica Morrow
No abstract text is available yet for this article.
January 17, 2024: JAMA Surgery
https://read.qxmd.com/read/38206508/aso-visual-abstract-do-her2-low-tumors-have-a-distinct-clinicopathologic-phenotype
#8
JOURNAL ARTICLE
Natália Polidorio, Giacomo Montagna, Varadan Sevilimedu, Tiana Le, Monica Morrow
No abstract text is available yet for this article.
January 11, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38158494/do-her2-low-tumors-have-a-distinct-clinicopathologic-phenotype
#9
JOURNAL ARTICLE
Natália Polidorio, Giacomo Montagna, Varadan Sevilimedu, Tiana Le, Monica Morrow
BACKGROUND: Breast cancer subtypes, distinguished by hormone receptor (HR) and HER2 status, have different clinicopathologic features. With recognition of the clinical relevance of HER2-low, there is debate as to whether this is a distinct subtype. Our study aimed to determine whether HER2-low breast cancers have specific clinicopathologic features that differ from those of HER2-negative and HER2-positive cancers. PATIENTS AND METHODS: A total of 11,072 patients undergoing upfront surgery from 1998 to 2010 were identified from a single-institution prospectively maintained database...
December 29, 2023: Annals of Surgical Oncology
https://read.qxmd.com/read/38105382/aso-visual-abstract-patient-reported-outcomes-in-patients-undergoing-lumpectomy%C3%A2-with-and%C3%A2-without%C3%A2-defect%C3%A2-closure
#10
JOURNAL ARTICLE
Emily Palmquist, Varadan Sevilimedu, Paula Garcia, Tiana Le, Xinyi Zhang, Katja Pinker-Domenig, Matthew G Hanna, Jonas A Nelson, Monica Morrow, Mahmoud El-Tamer
No abstract text is available yet for this article.
December 17, 2023: Annals of Surgical Oncology
https://read.qxmd.com/read/38063989/patient-reported-outcomes-in-patients-undergoing-lumpectomy-with-and-without-defect-closure
#11
JOURNAL ARTICLE
Emily Palmquist, Varadan Sevilimedu, Paula Garcia, Tiana Le, Xinyi Zhang, Katja Pinker-Domenig, Matthew G Hanna, Jonas A Nelson, Monica Morrow, Mahmoud El-Tamer
BACKGROUND: The effect of lumpectomy defect repair (a level 1 oncoplastic technique) on patient-reported breast satisfaction among patients undergoing lumpectomy has not yet been investigated. METHODS: Patients undergoing lumpectomy at our institution between 2018 and 2020 with or without repair of their lumpectomy defect during index operation, comprised our study population. The BREAST-Q quality-of-life questionnaire was administered preoperatively, and at 6 months, 1 year, and 2 years postoperatively...
December 8, 2023: Annals of Surgical Oncology
https://read.qxmd.com/read/38017121/aso-visual-abstract-examining-race-and-patient-reported-outcomes-after-contralateral-prophylactic-mastectomy-with-reconstruction
#12
JOURNAL ARTICLE
Sara P Myers, Solange Bayard, Audree B Tadros, Varadan Sevilimedu, Evan Matros, Jonas A Nelson, Tiana Le, Paula Garcia, Monica Morrow, Minna K Lee
No abstract text is available yet for this article.
November 28, 2023: Annals of Surgical Oncology
https://read.qxmd.com/read/37973646/examining-race-and-patient-reported-outcomes-after-contralateral-prophylactic-mastectomy-with-reconstruction
#13
JOURNAL ARTICLE
Sara P Myers, Solange Bayard, Audree B Tadros, Varadan Sevilimedu, Evan Matros, Jonas A Nelson, Tiana Le, Paula Garcia, Monica Morrow, Minna K Lee
BACKGROUND: Little is known regarding racial differences in satisfaction and quality of life (QOL) after contralateral prophylactic mastectomy (CPM). In this study, we aim to characterize associations between race, and postoperative satisfaction and well-being, utilizing the validated BREAST-Q patient-reported outcome measure. PATIENTS AND METHODS: Patients were eligible if they were diagnosed with stage 0-III unilateral breast cancer and underwent mastectomy with immediate reconstruction at our institution between 2016 and 2022...
November 16, 2023: Annals of Surgical Oncology
https://read.qxmd.com/read/37947183/biallelic-creld1-variants-cause-a-multisystem-syndrome-including-neurodevelopmental-phenotypes-cardiac-dysrhythmias-and-frequent-infections
#14
JOURNAL ARTICLE
Lauren Jeffries, Emily K Mis, Kirsty McWalter, Sandra Donkervoort, Nina N Brodsky, Jean-Marie Carpier, Weizhen Ji, Cristian Ionita, Bhaskar Roy, Jon S Morrow, Armine Darbinyan, Krishna Iyer, Ritu B Aul, Siddharth Banka, Katherine R Chao, Laura Cobbold, Stacey Cohen, Helena M Custodio, Margaret Drummond-Borg, Frances Elmslie, Erika Finanger, Bryan E Hainline, Ingo Helbig, Stacy Hewson, Ying Hu, Adam Jackson, Dragana Josifova, Monica Konstantino, Meganne E Leach, Bryan Mak, David McCormick, Elisabeth McGee, Stanley Nelson, Joanne Nguyen, Kimberly Nugent, Lucy Ortega, Howard P Goodkin, Elizabeth Roeder, Sani Roy, Katie Sapp, Dimah Saade, Sanjay M Sisodiya, Karen Stals, Shelley Towner, William Wilson, Mustafa K Khokha, Carsten G Bönnemann, Carrie L Lucas, Saquib A Lakhani
PURPOSE: We sought to delineate a multisystem disorder caused by recessive CRELD1 variants. METHODS: The impact of CRELD1 variants was characterized through an international collaboration utilizing next generation DNA sequencing, gene knockdown and protein overexpression in Xenopus tropicalis, and in vitro analysis of patient immune cells. RESULTS: Biallelic variants in CRELD1 were found in 18 participants from 14 families. Affected individuals displayed an array of phenotypes involving developmental delay, early-onset epilepsy, and hypotonia, with about half demonstrating cardiac arrhythmias and some experiencing recurrent infections...
November 6, 2023: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://read.qxmd.com/read/37946042/the-crtc-1-transcriptional-domain-is-required-for-compass-complex-mediated-longevity-in-c-elegans
#15
JOURNAL ARTICLE
Carlos G Silva-García, Laura I Láscarez-Lagunas, Katharina Papsdorf, Caroline Heintz, Aditi Prabhakar, Christopher S Morrow, Lourdes Pajuelo Torres, Arpit Sharma, Jihe Liu, Monica P Colaiácovo, Anne Brunet, William B Mair
Loss of function during aging is accompanied by transcriptional drift, altering gene expression and contributing to a variety of age-related diseases. CREB-regulated transcriptional coactivators (CRTCs) have emerged as key regulators of gene expression that might be targeted to promote longevity. Here we define the role of the Caenorhabditis elegans CRTC-1 in the epigenetic regulation of longevity. Endogenous CRTC-1 binds chromatin factors, including components of the COMPASS complex, which trimethylates lysine 4 on histone H3 (H3K4me3)...
November 9, 2023: Nature aging
https://read.qxmd.com/read/37815683/aso-visual-abstract-mutational-status-is-associated-with-higher-rate-of-pathologic-complete-response-after-neoadjuvant-chemotherapy-in-hormone-receptor-positive-breast-cancer
#16
JOURNAL ARTICLE
Sara P Myers, Varadan Sevilimedu, Andrea V Barrio, Audree B Tadros, Anita Mamtani, Mark E Robson, Monica Morrow, Minna K Lee
No abstract text is available yet for this article.
October 10, 2023: Annals of Surgical Oncology
https://read.qxmd.com/read/37798552/mutational-status-is-associated-with-a-higher-rate-of-pathologic-complete-response-after-neoadjuvant-chemotherapy-in-hormone-receptor-positive-breast-cancer
#17
JOURNAL ARTICLE
Sara P Myers, Varadan Sevilimedu, Andrea V Barrio, Audree B Tadros, Anita Mamtani, Mark E Robson, Monica Morrow, Minna K Lee
BACKGROUND: Pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) occurs in up to 20% of hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) breast cancers. Whether this differs among BRCA mutation carriers is uncertain. This study compared pCR between BRCA1/2 mutation carriers and matched sporadic control subjects. METHODS: From November 2013 to January 2022, this study identified 522 consecutive women with clinical stage I to III HR+/HER2- breast cancer treated with NAC and surgery...
October 5, 2023: Annals of Surgical Oncology
https://read.qxmd.com/read/37768520/impact-of-reactive-changes-on-multigene-testing-histopathologic-analysis-of-low-grade-breast-cancers-with-high-risk-21-gene-recurrence-scores
#18
JOURNAL ARTICLE
Anne Grabenstetter, Edi Brogi, Donna M Thompson, Victoria S Blinder, Larry Norton, Monica Morrow, Mark E Robson, Hannah Y Wen
PURPOSE: The 21-gene recurrence score (RS) assay predicts the recurrence risk and magnitude of chemotherapy benefit in patients with invasive breast cancer (BC). This study examined low-grade tumors yielding a high-risk RS and their outcomes.Kindly check the edit made in the article titleOk  METHODS: We compared patients with grade 1 BC and a high-risk RS to those with low-risk RS. Histologic sections were reviewed and features reported to elevate the RS were noted, mainly biopsy cavity and reactive stromal changes (BXC)...
September 28, 2023: Breast Cancer Research and Treatment
https://read.qxmd.com/read/37725704/the-next-generation-oral-selective-estrogen-receptor-degrader-camizestrant-azd9833-suppresses-er-breast-cancer-growth-and-overcomes-endocrine-and-cdk4-6-inhibitor-resistance
#19
JOURNAL ARTICLE
Mandy Lawson, Natalie Cureton, Susana Ros, Azadeh Cheraghchi-Bashi-Astaneh, Jelena Urosevic, Sophie D'Arcy, Oona Delpuech, Michelle DuPont, David I Fisher, Eric T Gangl, Hilary Lewis, Dawn Trueman, Neha Wali, Stuart Charles Williamson, Jennifer Moss, Elodie Montaudon, Héloïse Derrien, Elisabetta Marangoni, Ricardo J Miragaia, Sladjana Gagrica, Pablo Morentin Gutierrez, Thomas Moss, Gareth A Maglennon, Daniel Sutton, Radoslaw Polanski, Alan Rosen, Jonathan Cairns, Pei Zhang, Mònica Sánchez-Guixé, Violeta Serra, Susan E Critchlow, James S Scott, Justin P O Lindemann, Simon T Barry, Teresa Klinowska, Christopher J Morrow, Larissa S Carnevalli
Oral selective estrogen receptor degraders (SERDs) could become the backbone of endocrine therapy (ET) for estrogen receptor-positive (ER+) breast cancer, as they achieve greater inhibition of ER-driven cancers than current ETs and overcome key resistance mechanisms. In this study, we evaluated the preclinical pharmacology and efficacy of the next-generation oral SERD camizestrant (AZD9833) and assessed ER co-targeting strategies by combining camizestrant with CDK4/6 inhibitors (CDK4/6i) and PI3K/AKT/mTOR-targeted therapy in models of progression on CDK4/6i and/or ET...
September 19, 2023: Cancer Research
https://read.qxmd.com/read/37725413/digital-health-implementation-strategies-coproduced-with-adults-with-acquired-brain-injury-their-close-others-and-clinicians-mixed-methods-study-with-collaborative-autoethnography-and-network-analysis
#20
JOURNAL ARTICLE
Melissa Miao, Rosemary Morrow, Alexander Salomon, Ben Mcculloch, Jean-Christophe Evain, Meg Rebecca Wright, Marie Therese Murphy, Monica Welsh, Liz Williams, Emma Power, Rachael Rietdijk, Deborah Debono, Melissa Brunner, Leanne Togher
BACKGROUND: Acquired brain injuries (ABIs), such as stroke and traumatic brain injury, commonly cause cognitive-communication disorders, in which underlying cognitive difficulties also impair communication. As communication is an exchange with others, close others such as family and friends also experience the impact of cognitive-communication impairment. It is therefore an internationally recommended best practice for speech-language pathologists to provide communication support to both people with ABI and the people who communicate with them...
September 19, 2023: Journal of Medical Internet Research
keyword
keyword
110606
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.