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https://www.readbyqxmd.com/read/27647149/controlled-evacuation-using-the-biocompatible-and-energy-efficient-microfluidic-ejector
#1
V N Lad, Swati Ralekar
Development of controlled vacuum is having many applications in the realm of biotechnology, cell transfer, gene therapy, biomedical engineering and other engineering activities involving separation or chemical reactions. Here we show the controlled vacuum generation through a biocompatible, energy efficient, low-cost and flexible miniature device. We have designed and fabricated microfluidic devices from polydimethylsiloxane which are capable of producing vacuum at a highly controlled rate by using water as a motive fluid...
October 2016: Biomedical Microdevices
https://www.readbyqxmd.com/read/27416660/-minimally-invasive-techniques-in-the-treatment-of-benign-prostatic-hyperplasia-an-update
#2
REVIEW
Yi-ping Lu, Jia-yu Liang
Lower urinary tract symptoms (LUTS) resulting from benign prostatic hyperplasia (BPH) obviously impair the quality of life of middle-aged and elderly men. Current management of BPH includes wait-and-watch, medical therapy, and conventional surgery. As a new approach, minimally invasive surgery has been playing an increasingly important role in the management of BPH, with potential advantages of less operative trauma, quicker recovery, lower risk of postoperative complications and higher quality of life. This review mainly discusses prostatic urethral lift (Urolift® System), transurethral water vapor therapy (Rezūm® System) and robot-guided high-energy water ablation (PROCEPT Aquablation™ System)...
May 2016: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/27240752/comparison-of-the-properties-of-membranes-produced-with-alginate-and-chitosan-from-mushroom-and-from-shrimp
#3
Andréa C K Bierhalz, Cecília Buzatto Westin, Ângela Maria Moraes
Dense and porous chitosan-alginate membranes (1:1 in mass) useful as coverages of skin wounds treated through cell therapy were produced using chitosan of different chain sizes from fungal (white mushrooms) and animal (shrimp shells) sources. Porous materials were obtained by adding the surfactant Poloxamer 188 to the formulations. The influence of chitosan type on membranes physicochemical properties and toxicity to fibroblasts was evaluated. Porosity was noticed to be more pronounced in membranes obtained with fungal chitosan and increased with its molecular mass...
October 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27129767/erectile-and-ejaculatory-function-preserved-with-convective-water-vapor-energy-treatment-of-lower-urinary-tract-symptoms-secondary-to-benign-prostatic-hyperplasia-randomized-controlled-study
#4
Kevin T McVary, Steven N Gange, Marc C Gittelman, Kenneth A Goldberg, Kalpesh Patel, Neal D Shore, Richard M Levin, Michael Rousseau, J Randolf Beahrs, Jed Kaminetsky, Barrett E Cowan, Christopher H Cantrill, Lance A Mynderse, James C Ulchaker, Thayne R Larson, Christopher M Dixon, Claus G Roehrborn
INTRODUCTION: Most surgical treatments for male lower urinary tract symptoms and benign prostatic hyperplasia affect erectile and ejaculatory functions negatively, leading to patient dissatisfaction. AIM: To determine whether water vapor thermal therapy, when conducted in a randomized controlled trial, would significantly improve lower urinary tract symptoms secondary to benign prostatic hyperplasia and urinary flow rate while preserving erectile and ejaculatory functions...
June 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/26876862/effect-of-vapor-phase-glutaraldehyde-crosslinking-on-electrospun-starch-fibers
#5
Wenyu Wang, Xin Jin, Yonghao Zhu, Chengzhang Zhu, Jian Yang, Hongjie Wang, Tong Lin
In this work, we have proven that starch nanofibrous membranes with high tensile strength, water stability and non-cytotoxicity can be produced by electrospinning of starch solution and post-treatment with GTA in vapor phase. GTA vapor phase crosslinking plays a key role in forming water-stable nanofiber membrane and improving the mechanical properties. Comparing with non-crosslinked starch fibers, the crosslinked fibers are increased by nearly 10 times in tensile strength. The crosslinked starch fibrous membranes are non-cytotoxic...
April 20, 2016: Carbohydrate Polymers
https://www.readbyqxmd.com/read/26776874/gentamicin-sulfate-loaded-porous-natural-rubber-films-for-wound-dressing
#6
Thawatchai Phaechamud, Pongsathorn Issarayungyuen, Wiwat Pichayakorn
Antimicrobial wound dressings have been developed for effectiveness of wound therapy. In this study, gentamicin sulfate was loaded into modified porous natural rubber films. The hydrophilic porous structure in natural rubber films was formed when the polar liquid such as glycerin or triethyl citrate and hydrophilic xanthan gum were blended. Film properties including morphology, drug release, water sorption and erosion, mechanical property, adhesive property, surface free energy, water vapor transmission rate, oxygen permeation, and antimicrobial activity were determined...
April 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/26647455/inspiratory-tube-condensation-during-high-flow-nasal-cannula-therapy-a-bench-study
#7
Yusuke Chikata, Kazuaki Unai, Masayo Izawa, Nao Okuda, Jun Oto, Masaji Nishimura
BACKGROUND: High-flow nasal cannula (HFNC) therapy provides better humidification than conventional oxygen therapy. To allay loss of vapor as condensation, a servo-controlled heating wire is incorporated in the inspiratory tube, but condensation is not completely avoidable. We investigated factors that might affect condensation: thermal characteristics of the inspiratory tube, HFNC flow, and ambient temperature. METHODS: We evaluated 2 types of HFNC tubes, SLH Flex 22-mm single tube and RT202...
March 2016: Respiratory Care
https://www.readbyqxmd.com/read/26614889/minimally-invasive-prostate-convective-water-vapor-energy-ablation-a-multicenter-randomized-controlled-study-for-the-treatment-of-lower-urinary-tract-symptoms-secondary-to-benign-prostatic-hyperplasia
#8
Kevin T McVary, Steven N Gange, Marc C Gittelman, Kenneth A Goldberg, Kalpesh Patel, Neal D Shore, Richard M Levin, Michael Rousseau, J Randolf Beahrs, Jed Kaminetsky, Barrett E Cowan, Christopher H Cantrill, Lance A Mynderse, James C Ulchaker, Thayne R Larson, Christopher M Dixon, Claus G Roehrborn
PURPOSE: This report reveals the results of a multicenter, randomized, controlled study using transurethral prostate convective water vapor thermal energy to treat lower urinary tract symptoms associated with benign prostatic hyperplasia. MATERIALS AND METHODS: Men 50 years old or older with an International Prostate Symptom Score of 13 or greater, maximum flow rate of 15 ml per second or less and prostate size 30 to 80 cc were randomized 2:1 between thermal therapy with the Rezūm® System and control...
May 2016: Journal of Urology
https://www.readbyqxmd.com/read/26465218/nebulized-epinephrine-limits-pulmonary-vascular-hyperpermeability-to-water-and-protein-in-ovine-with-burn-and-smoke-inhalation-injury
#9
Ernesto Lopez, Osamu Fujiwara, Francisco Lima-Lopez, Oscar E Suman, Ronald P Mlcak, Hal K Hawkins, Robert A Cox, David N Herndon, Donald S Prough, Perenlei Enkhbaatar
OBJECTIVES: To test the hypothesis that nebulized epinephrine ameliorates pulmonary dysfunction by dual action-bronchodilation (β2-adrenergic receptor agonism) and attenuation of airway hyperemia (α1-adrenergic receptor agonism) with minimal systemic effects. DESIGN: Randomized, controlled, prospective, and large animal translational studies. SETTING: University large animal ICU. SUBJECTS: Twelve chronically instrumented sheep...
February 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/26339963/preventing-or-reducing-smoking-related-complications-in-otologic-and-neurotologic-surgery
#10
REVIEW
Justin S Golub, Ravi N Samy
PURPOSE OF REVIEW: To discuss effects of smoking on otologic surgery in an era of electronic (e-) cigarettes and proposals for legalization of marijuana. Physiologic mechanisms and clinical outcomes are presented. RECENT FINDINGS: Tobacco smoke can cause a variety of tissue effects that may adversely impact otologic surgery outcomes. Results in tympanoplasty using temporalis fascia are inferior in smokers compared with nonsmokers. More recent data show that in cartilage tympanoplasty, graft incorporation rates in smokers may approach those of nonsmokers...
October 2015: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/26216644/efficacy-and-safety-of-rez%C3%A5-m-system-water-vapor-treatment-for-lower-urinary-tract-symptoms-secondary-to-benign-prostatic-hyperplasia
#11
MULTICENTER STUDY
Christopher Dixon, Edwin Rijo Cedano, Dalibor Pacik, Viteslav Vit, Gabriel Varga, Lennart Wagrell, Magnus Tornblom, Lance Mynderse, Thayne Larson
OBJECTIVE: To assess 1-year efficacy and safety data from pilot trials of the Rezūm System water vapor to treat lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: A total of 65 men with symptoms of moderate to severe BPH were enrolled in pilot studies at centers in the Dominican Republic, the Czech Republic, and Sweden. Each patient was treated with transurethral delivery of sterile water vapor (steam). International Prostate Symptom Score (IPSS), peak urinary flow (Qmax), quality of life (QoL), postvoid residual, International Index of Erectile Function, and prostate-specific antigen were evaluated at 1 week and 1, 3, 6, and 12 months post-treatment...
November 2015: Urology
https://www.readbyqxmd.com/read/26216316/acute-exacerbation-of-idiopathic-pulmonary-fibrosis-after-inhalation-of-a-water-repellent
#12
David Bennett, Elena Bargagli, Rosa Metella Refini, Maria Grazia Pieroni, Antonella Fossi, Riccardo Romeo, Luca Volterrani, Maria Antonietta Mazzei, Paola Rottoli
The natural course of idiopathic pulmonary fibrosis (IPF) is unpredictable at the time of diagnosis. Some patients may experience episodes of acute respiratory worsening that have been termed acute exacerbations. A 58-year-old male was admitted to our Emergency Department due to progressive and intense dyspnea and dry cough after accidental inhalation of waterproof's vapor containing siloxanes. Chest high resolution computed tomography (HRCT) scan showed diffuse and bilateral ground glass attenuation, basal predominant reticular abnormalities and subpleural honeycombing...
2015: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/26070583/device-cleaning-and-infection-control-in-aerosol-therapy
#13
REVIEW
Catherine A O'Malley
Aerosol delivery equipment used to administer inhaled medications includes the nebulizer, positive expiratory pressure devices added to the nebulizer, and valved holding chambers (spacers). These devices are semi-critical medical devices, and as such, infection prevention and control (IPC) guidelines recommend that they be cleaned, disinfected, rinsed with sterile water, and air-dried. There is confusion surrounding the care of aerosol devices because of inconsistencies in the various published IPC guidelines, lack of a standard of practice among institutions and respiratory therapists (RTs), and manufacturer's instructions for use of these devices are not always compatible with guidelines or practice...
June 2015: Respiratory Care
https://www.readbyqxmd.com/read/25826652/numerical-models-to-evaluate-the-temperature-increase-induced-by-ex-vivo-microwave-thermal-ablation
#14
M Cavagnaro, R Pinto, V Lopresto
Microwave thermal ablation (MTA) therapies exploit the local absorption of an electromagnetic field at microwave (MW) frequencies to destroy unhealthy tissue, by way of a very high temperature increase (about 60 °C or higher). To develop reliable interventional protocols, numerical tools able to correctly foresee the temperature increase obtained in the tissue would be very useful. In this work, different numerical models of the dielectric and thermal property changes with temperature were investigated, looking at the simulated temperature increments and at the size of the achievable zone of ablation...
April 21, 2015: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/25639195/double-layer-adhesive-silicone-dressing-as-a-potential-dermal-drug-delivery-film-in-scar-treatment
#15
Krystyna Mojsiewicz-Pieńkowska, Marzena Jamrógiewicz, Maria Żebrowska, Barbara Mikolaszek, Małgorzata Sznitowska
The present studies focused on the evaluation of design of an adhesive silicone film intended for scar treatment. Developed silicone double layer film was examined in terms of its future relevance to therapy and applicability on the human skin considering properties which included in vitro permeability of water vapor and oxygen. In order to adapt the patches for medical use in the future there were tested such properties as in vitro adhesion and occlusion related to in vivo hydration. From the silicone rubbers double layer silicone film was prepared: a non-adhesive elastomer as a drug carrier (the matrix for active substances - enoxaparin sodium - low molecular weight heparin) and an adhesive elastomer, applied on the surface of the matrix...
March 15, 2015: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/25602781/intrapulpal-temperature-changes-during-root-surface-irradiation-with-dual-wavelength-laser-2780-and-940-nm-in-vitro-study
#16
Rene Franzen, Borna Rashidisangsary, Seda Ozturan, Leon Vanweersch, Norbert Gutknecht
This work reports that the ablation volume and rate of porcine skin changed significantly with the change of skin water content. Under the same laser irradiation conditions (532 nm Nd:YAG laser, pulse width = 11.5 ns, pulse energy = 1.54 J, beam radius = 0.54 mm), the ablation volume dropped by a factor of 4 as the skin water content decreased from 40 wt. % (native) to 19 wt. % with a change in the ablation rate below and above around 25 wt. %. Based on the ablation characteristics observed by in situ shadowgraph images and the calculated tissue temperatures, it is considered that an explosive rupture by rapid volumetric vaporization of water is responsible for the ablation of the high water content of skin, whereas thermal disintegration of directly irradiated surface layer is responsible for the low water content of skin...
January 2015: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/25581397/influence-of-water-content-on-the-ablation-of-skin-with-a-532-nm-nanosecond-nd-yag-laser
#17
Soogeun Kim, Tae Joong Eom, Sungho Jeong
This work reports that the ablation volume and rate of porcine skin changed significantly with the change of skin water content. Under the same laser irradiation conditions (532 nm Nd:YAG laser, pulse width = 11.5 ns, pulse energy = 1.54 J, beam radius = 0.54 mm), the ablation volume dropped by a factor of 4 as the skin water content decreased from 40 wt. % (native) to 19 wt. % with a change in the ablation rate below and above around 25 wt. %. Based on the ablation characteristics observed by in situ shadowgraph images and the calculated tissue temperatures, it is considered that an explosive rupture by rapid volumetric vaporization of water is responsible for the ablation of the high water content of skin, whereas thermal disintegration of directly irradiated surface layer is responsible for the low water content of skin...
January 2015: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/25499179/achromobacter-bacteraemia-outbreak-in-a-paediatric-onco-haematology-department-related-to-strain-with-high-surviving-ability-in-contaminated-disinfectant-atomizers
#18
E Hugon, H Marchandin, M Poirée, T Fosse, N Sirvent
BACKGROUND: Achromobacter spp. are Gram-negative bacilli from aqueous environments, occasionally involved in bacteraemia in immunocompromised hosts and in outbreaks. AIM: We describe the characteristics of an achromobacter bacteraemia outbreak in a paediatric onco-haematology department. METHODS: Throughout a one-year period, 16 blood cultures from seven patients were positive for Achromobacter sp. All patients were immunocompromised, febrile, and central venous catheter (CVC) holders...
February 2015: Journal of Hospital Infection
https://www.readbyqxmd.com/read/25336993/technology-update-bronchoscopic-thermal-vapor-ablation-for-managing-severe-emphysema
#19
REVIEW
Daniela Gompelmann, Ralf Eberhardt, Felix Jf Herth
Bronchoscopic thermal vapor ablation (BTVA) is an endoscopic lung volume reduction therapy that presents an effective treatment approach in patients with severe upper lobe-predominant emphysema. By instillation of heated water vapor, an inflammatory reaction is induced, leading to fibrosis and scarring of the lung parenchyma, resulting in lobar volume reduction. Clinical single-arm trials demonstrated great outcomes, with significant improvement of lung function, exercise capacity, and quality of life. As the BTVA-induced local inflammatory response that seems to be essential for the desired lobar volume reduction can be associated with transient clinical worsening, strict monitoring of the patients is required...
2014: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/25327035/water-pipes-and-e-cigarettes-new-faces-of-an-ancient-enemy
#20
REVIEW
Rucha S Dagaonkar, Zarir F Udwadi
In a world grappling with tobacco addiction, the hookah (water-pipe) and the electronic cigarette (e-cigarette) are creating new problems. Apart from posing the inherent danger of nicotine addiction, they both seem to be wolves cloaked in the sheep-skin of consumer-perceived safety, at least in comparison to the cigarette. However it seems that the e-cigarette may have a role in a nicotine-replacement therapy. There has been a wave of interest around the world in analysing these phenomena. The following review discusses the current data regarding the hookah and the e-cigarette...
April 2014: Journal of the Association of Physicians of India
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