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https://www.readbyqxmd.com/read/28877412/neuronal-differentiation-of-human-mesenchymal-stem-cells-in-response-to-the-domain-size-of-graphene-substrates
#1
Yoo-Jung Lee, Tae Hoon Seo, Seul-A Lee, Wonhee Jang, Myung Jong Kim, Jung-Suk Sung
Graphene is a non-cytotoxic monolayer platform with unique physical, chemical, and biological properties. It has been demonstrated that graphene substrate may provide a promising biocompatible scaffold for stem cell therapy. Since chemical vapor deposited graphene has a two dimensional poly-crystalline structure, it is important to control the individual domain size to obtain desirable properties for nano-material. However, the biological effects mediated by differences in domain size of graphene have not yet been reported...
September 6, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28861405/procedural-techniques-and-multicenter-postmarket-experience-using-minimally-invasive-convective-radiofrequency-thermal-therapy-with-rez%C3%A5-m-system-for-treatment-of-lower-urinary-tract-symptoms-due-to-benign-prostatic-hyperplasia
#2
Micheal F Darson, Erik E Alexander, Zvi J Schiffman, Michael Lewitton, Robert A Light, Mark A Sutton, Carlos Delgado-Rodriguez, Ricardo R Gonzalez
OBJECTIVE: This report evaluates clinical experience with the Rezūm system after US Food and Drug Administration clearance in consecutive cases accrued by multiple community urologists for the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). Treatment techniques for transurethral convective radiofrequency water-vapor thermal therapy and outcomes with up to 12 months' follow-up are presented. MATERIALS AND METHODS: A total of 131 patients with moderate-severe LUTS were included in a retrospective analysis of BPH procedures with the Rezūm system...
2017: Research and Reports in Urology
https://www.readbyqxmd.com/read/28780635/convective-radiofrequency-water-vapor-thermal-therapy-with-rez%C3%A5-m-system
#3
REVIEW
Sevann Helo, Bradley Holland, Kevin T McVary
PURPOSE: Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) are amongst the most commonly treated conditions by urologists. Minimally invasive therapies for the treatment of BPH/LUTS have garnered increased interest as new technology has emerged, improving durability, efficacy, and safety. This paper reviews the most recent literature regarding water vapor therapy, a convective thermal therapy that ablates prostatic tissue. RECENT FINDINGS: The current literature includes a pilot study of 65 men and a randomized controlled trial (RCT) of 197 men investigating the efficacy and safety profile of water vapor therapy up to 2 years...
October 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28490907/perspective-on-the-rez%C3%A5-m-%C3%A2-system-a-minimally-invasive-treatment-strategy-for-benign-prostatic-hyperplasia-using-convective-radiofrequency-water-vapor-thermal-therapy
#4
Henry H Woo, Ricardo R Gonzalez
Convective radiofrequency (RF) water vapor thermal therapy is a minimally invasive office or outpatient procedure for the treatment of bothersome moderate-to-severe lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). It provides an option for patients seeking rapid and durable relief of urinary symptoms, improved quality of life, and preservation of sexual function as an alternative to long-term use of drugs and avoidance of the potential side effects of pharmaceuticals or invasive BPH surgery...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/28450246/hypericum-perforatum-incorporated-chitosan-films-as-potential-bioactive-wound-dressing-material
#5
Seda Güneş, Funda Tıhmınlıoğlu
Recent studies in wound dressing applications offer new therapies and promote wound healing process. The aim of this study was to develop Hypericum perforatum (St John's Wort) oil incorporated chitosan films for wound dressing applications. H. perforatum oil as a potential therapeutic agent was encapsulated in chitosan film to achieve a better wound dressing material. Oil incorporated chitosan films were successfully prepared by solvent casting method in different oil concentrations (0.25-1.5%v/v). Water vapor permeability (WVP), mechanical test, swelling behavior and surface hydrophobicity were performed in order to characterize the prepared films...
September 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28378308/current-advancements-of-magnetic-nanoparticles-in-adsorption-and-degradation-of-organic-pollutants
#6
Mazhar Ul-Islam, Muhammad Wajid Ullah, Shaukat Khan, Shehrish Manan, Waleed Ahmad Khattak, Wasi Ahmad, Nasrullah Shah, Joong Kon Park
Nanotechnology is a fast-emerging field and has received applications in almost every field of life. Exploration of new synthetic technologies for size and shape control of nanomaterials is getting immense consideration owing to their exceptional properties and applications. Magnetic nanoparticles (MNPs) are among the most important group of nanoparticles thanks to their diverse applications in medical, electronic, environmental, and industrial sectors. There have been numerous synthetic routes of MNPs including thermal decomposition, co-precipitation, microemulsion, microwave assisted, chemical vapor deposition, combustion synthesis, and laser pyrolysis synthesis...
May 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28088847/vapor-and-gas-bubble-growth-dynamics-around-laser-irradiated-water-immersed-plasmonic-nanoparticles
#7
Yuliang Wang, Mikhail E Zaytsev, Hai Le The, Jan C T Eijkel, Harold J W Zandvliet, Xuehua Zhang, Detlef Lohse
Microbubbles produced by exposing water-immersed metallic nanoparticles to resonant light play an important role in emerging and efficient plasmonic-enhanced processes for catalytic conversion, solar energy harvesting, biomedical imaging, and cancer therapy. How do these bubbles form, and what is their gas composition? In this paper, the growth dynamics of nucleating bubbles around laser-irradiated, water-immersed Au plasmonic nanoparticles are studied to determine the exact origin of the occurrence and growth of these bubbles...
February 28, 2017: ACS Nano
https://www.readbyqxmd.com/read/27993667/convective-thermal-therapy-durable-2-year-results-of-randomized-controlled-and-prospective-crossover-studies-for-treatment-of-lower-urinary-tract-symptoms-due-to-benign-prostatic-hyperplasia
#8
Claus G Roehrborn, Steven N Gange, Marc C Gittelman, Kenneth A Goldberg, Kalpesh Patel, Neal D Shore, Richard M Levin, Michael Rousseau, J Randolf Beahrs, Jed Kaminetsky, Barrett E Cowan, Christopher H Cantrill, Lance A Mynderse, James C Ulchaker, Thayne R Larson, Christopher M Dixon, Kevin T McVary
PURPOSE: We report 2-year outcomes of a multicenter randomized controlled trial plus 1-year results of a crossover trial after treatment with convective radiofrequency water vapor thermal energy for lower urinary tract symptoms due to benign prostatic hyperplasia. MATERIALS AND METHODS: A total of 197 men at least 50 years old with I-PSS (International Prostate Symptom Score) 13 or greater, maximum flow rate 15 ml per second or less and prostate size 30 to 80 cc were randomized 2:1 to thermal therapy with the Rezūm® System or a control group...
June 2017: Journal of Urology
https://www.readbyqxmd.com/read/27921028/two-year-results-after-convective-radiofrequency-water-vapor-thermal-therapy-of-symptomatic-benign-prostatic-hyperplasia
#9
Christopher M Dixon, Edwin Rijo Cedano, Dalibor Pacik, Vítězslav Vit, Gabriel Varga, Lennart Wagrell, Thayne R Larson, Lance A Mynderse
OBJECTIVE: The objective of this study was to assess the effectiveness and safety of convective radiofrequency (RF) water vapor thermal therapy in men with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH); a pilot study design with 2-year follow-up evaluations. PATIENTS AND METHODS: Men aged ≥45 years with an International Prostate Symptom Score ≥13, a maximum urinary flow rate (Qmax) ≤15 mL/s, and prostate volume 20-120 cc were enrolled in a prospective, open-label pilot study using convective RF water vapor energy with the Rezūm System...
2016: Research and Reports in Urology
https://www.readbyqxmd.com/read/27647149/controlled-evacuation-using-the-biocompatible-and-energy-efficient-microfluidic-ejector
#10
V N Lad, Swati Ralekar
Development of controlled vacuum is having many applications in the realm of biotechnology, cell transfer, gene therapy, biomedical engineering and other engineering activities involving separation or chemical reactions. Here we show the controlled vacuum generation through a biocompatible, energy efficient, low-cost and flexible miniature device. We have designed and fabricated microfluidic devices from polydimethylsiloxane which are capable of producing vacuum at a highly controlled rate by using water as a motive fluid...
October 2016: Biomedical Microdevices
https://www.readbyqxmd.com/read/27416660/-minimally-invasive-techniques-in-the-treatment-of-benign-prostatic-hyperplasia-an-update
#11
REVIEW
Yi-ping Lu, Jia-yu Liang
Lower urinary tract symptoms (LUTS) resulting from benign prostatic hyperplasia (BPH) obviously impair the quality of life of middle-aged and elderly men. Current management of BPH includes wait-and-watch, medical therapy, and conventional surgery. As a new approach, minimally invasive surgery has been playing an increasingly important role in the management of BPH, with potential advantages of less operative trauma, quicker recovery, lower risk of postoperative complications and higher quality of life. This review mainly discusses prostatic urethral lift (Urolift® System), transurethral water vapor therapy (Rezūm® System) and robot-guided high-energy water ablation (PROCEPT Aquablation™ System)...
May 2016: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/27240752/comparison-of-the-properties-of-membranes-produced-with-alginate-and-chitosan-from-mushroom-and-from-shrimp
#12
COMPARATIVE STUDY
Andréa C K Bierhalz, Cecília Buzatto Westin, Ângela Maria Moraes
Dense and porous chitosan-alginate membranes (1:1 in mass) useful as coverages of skin wounds treated through cell therapy were produced using chitosan of different chain sizes from fungal (white mushrooms) and animal (shrimp shells) sources. Porous materials were obtained by adding the surfactant Poloxamer 188 to the formulations. The influence of chitosan type on membranes physicochemical properties and toxicity to fibroblasts was evaluated. Porosity was noticed to be more pronounced in membranes obtained with fungal chitosan and increased with its molecular mass...
October 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27129767/erectile-and-ejaculatory-function-preserved-with-convective-water-vapor-energy-treatment-of-lower-urinary-tract-symptoms-secondary-to-benign-prostatic-hyperplasia-randomized-controlled-study
#13
RANDOMIZED CONTROLLED TRIAL
Kevin T McVary, Steven N Gange, Marc C Gittelman, Kenneth A Goldberg, Kalpesh Patel, Neal D Shore, Richard M Levin, Michael Rousseau, J Randolf Beahrs, Jed Kaminetsky, Barrett E Cowan, Christopher H Cantrill, Lance A Mynderse, James C Ulchaker, Thayne R Larson, Christopher M Dixon, Claus G Roehrborn
INTRODUCTION: Most surgical treatments for male lower urinary tract symptoms and benign prostatic hyperplasia affect erectile and ejaculatory functions negatively, leading to patient dissatisfaction. AIM: To determine whether water vapor thermal therapy, when conducted in a randomized controlled trial, would significantly improve lower urinary tract symptoms secondary to benign prostatic hyperplasia and urinary flow rate while preserving erectile and ejaculatory functions...
June 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/26876862/effect-of-vapor-phase-glutaraldehyde-crosslinking-on-electrospun-starch-fibers
#14
Wenyu Wang, Xin Jin, Yonghao Zhu, Chengzhang Zhu, Jian Yang, Hongjie Wang, Tong Lin
In this work, we have proven that starch nanofibrous membranes with high tensile strength, water stability and non-cytotoxicity can be produced by electrospinning of starch solution and post-treatment with GTA in vapor phase. GTA vapor phase crosslinking plays a key role in forming water-stable nanofiber membrane and improving the mechanical properties. Comparing with non-crosslinked starch fibers, the crosslinked fibers are increased by nearly 10 times in tensile strength. The crosslinked starch fibrous membranes are non-cytotoxic...
April 20, 2016: Carbohydrate Polymers
https://www.readbyqxmd.com/read/26776874/gentamicin-sulfate-loaded-porous-natural-rubber-films-for-wound-dressing
#15
Thawatchai Phaechamud, Pongsathorn Issarayungyuen, Wiwat Pichayakorn
Antimicrobial wound dressings have been developed for effectiveness of wound therapy. In this study, gentamicin sulfate was loaded into modified porous natural rubber films. The hydrophilic porous structure in natural rubber films was formed when the polar liquid such as glycerin or triethyl citrate and hydrophilic xanthan gum were blended. Film properties including morphology, drug release, water sorption and erosion, mechanical property, adhesive property, surface free energy, water vapor transmission rate, oxygen permeation, and antimicrobial activity were determined...
April 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/26647455/inspiratory-tube-condensation-during-high-flow-nasal-cannula-therapy-a-bench-study
#16
Yusuke Chikata, Kazuaki Unai, Masayo Izawa, Nao Okuda, Jun Oto, Masaji Nishimura
BACKGROUND: High-flow nasal cannula (HFNC) therapy provides better humidification than conventional oxygen therapy. To allay loss of vapor as condensation, a servo-controlled heating wire is incorporated in the inspiratory tube, but condensation is not completely avoidable. We investigated factors that might affect condensation: thermal characteristics of the inspiratory tube, HFNC flow, and ambient temperature. METHODS: We evaluated 2 types of HFNC tubes, SLH Flex 22-mm single tube and RT202...
March 2016: Respiratory Care
https://www.readbyqxmd.com/read/26614889/minimally-invasive-prostate-convective-water-vapor-energy-ablation-a-multicenter-randomized-controlled-study-for-the-treatment-of-lower-urinary-tract-symptoms-secondary-to-benign-prostatic-hyperplasia
#17
RANDOMIZED CONTROLLED TRIAL
Kevin T McVary, Steven N Gange, Marc C Gittelman, Kenneth A Goldberg, Kalpesh Patel, Neal D Shore, Richard M Levin, Michael Rousseau, J Randolf Beahrs, Jed Kaminetsky, Barrett E Cowan, Christopher H Cantrill, Lance A Mynderse, James C Ulchaker, Thayne R Larson, Christopher M Dixon, Claus G Roehrborn
PURPOSE: This report reveals the results of a multicenter, randomized, controlled study using transurethral prostate convective water vapor thermal energy to treat lower urinary tract symptoms associated with benign prostatic hyperplasia. MATERIALS AND METHODS: Men 50 years old or older with an International Prostate Symptom Score of 13 or greater, maximum flow rate of 15 ml per second or less and prostate size 30 to 80 cc were randomized 2:1 between thermal therapy with the Rezūm® System and control...
May 2016: Journal of Urology
https://www.readbyqxmd.com/read/26465218/nebulized-epinephrine-limits-pulmonary-vascular-hyperpermeability-to-water-and-protein-in-ovine-with-burn-and-smoke-inhalation-injury
#18
Ernesto Lopez, Osamu Fujiwara, Francisco Lima-Lopez, Oscar E Suman, Ronald P Mlcak, Hal K Hawkins, Robert A Cox, David N Herndon, Donald S Prough, Perenlei Enkhbaatar
OBJECTIVES: To test the hypothesis that nebulized epinephrine ameliorates pulmonary dysfunction by dual action-bronchodilation (β2-adrenergic receptor agonism) and attenuation of airway hyperemia (α1-adrenergic receptor agonism) with minimal systemic effects. DESIGN: Randomized, controlled, prospective, and large animal translational studies. SETTING: University large animal ICU. SUBJECTS: Twelve chronically instrumented sheep...
February 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/26339963/preventing-or-reducing-smoking-related-complications-in-otologic-and-neurotologic-surgery
#19
REVIEW
Justin S Golub, Ravi N Samy
PURPOSE OF REVIEW: To discuss effects of smoking on otologic surgery in an era of electronic (e-) cigarettes and proposals for legalization of marijuana. Physiologic mechanisms and clinical outcomes are presented. RECENT FINDINGS: Tobacco smoke can cause a variety of tissue effects that may adversely impact otologic surgery outcomes. Results in tympanoplasty using temporalis fascia are inferior in smokers compared with nonsmokers. More recent data show that in cartilage tympanoplasty, graft incorporation rates in smokers may approach those of nonsmokers...
October 2015: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/26216644/efficacy-and-safety-of-rez%C3%A5-m-system-water-vapor-treatment-for-lower-urinary-tract-symptoms-secondary-to-benign-prostatic-hyperplasia
#20
MULTICENTER STUDY
Christopher Dixon, Edwin Rijo Cedano, Dalibor Pacik, Viteslav Vit, Gabriel Varga, Lennart Wagrell, Magnus Tornblom, Lance Mynderse, Thayne Larson
OBJECTIVE: To assess 1-year efficacy and safety data from pilot trials of the Rezūm System water vapor to treat lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: A total of 65 men with symptoms of moderate to severe BPH were enrolled in pilot studies at centers in the Dominican Republic, the Czech Republic, and Sweden. Each patient was treated with transurethral delivery of sterile water vapor (steam). International Prostate Symptom Score (IPSS), peak urinary flow (Qmax), quality of life (QoL), postvoid residual, International Index of Erectile Function, and prostate-specific antigen were evaluated at 1 week and 1, 3, 6, and 12 months post-treatment...
November 2015: Urology
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