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Testosterone AND Supplement

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https://www.readbyqxmd.com/read/30411393/effects-of-branched-chain-amino-acid-supplementation-and-or-aerobic-exercise-on-mouse-sperm-quality-and-testosterone-production
#1
Mehrnoosh Bahadorani, Marziyeh Tavalaee, Navid Abedpoor, Kamran Ghaedi, Mohammad N Nazem, Mohammad H Nasr-Esfahani
Individuals who regularly exercise utilise dietary supplements to enhance their exercise routine and to increase lean mass. Branched-chain amino acids (BCAAs) are a popular supplement and have been shown to produce a number of beneficial effects in rodent and human models. Therefore, in the present study, the effect of exercise and/or BCAA on sperm parameters and testes tissue was assessed. C57BL6 male mice were divided to six groups; Control, Exercise (Exc), BCAA (consumes 20 mg BCAAs), BCAA+ (consumes 60 mg BCAAs), BCAA/Exc (consumes 20 mg BCAAs during aerobic training) and BCAA+/Exc (consumes 60 mg BCAAs during aerobic training)...
November 8, 2018: Andrologia
https://www.readbyqxmd.com/read/30396549/influence-of-temperature-serum-and-gonadotropin-supplementation-in-short-and-long-term-organotypic-culture-of-human-immature-testicular-tissue
#2
Jose V Medrano, Teresa Vilanova-Pérez, Victoria Fornés-Ferrer, Ana Navarro-Gomezlechon, María L Martínez-Triguero, Sofía García, Javier Gómez-Chacón, Ivan Povo, Antonio Pellicer, María M Andrés, Edurne Novella-Maestre
OBJECTIVE: To study how temperature, serum, and gonadotropin supplementation affect the organotypic culture of human immature testicular tissue (ITT) in vitro. DESIGN: Experimental basic science study. SETTING: Reproductive biology laboratory. PATIENT(S): ITT from 4 boys with cancer that had testicular tissue cryopreserved as part of their fertility preservation treatment. INTERVENTION(S): In vitro organotypic culture of ITT, exposed to different temperatures (37°C vs...
November 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/30391708/what-do-we-know-and-what-we-would-like-to-know-about-drone-homogenate
#3
REVIEW
Róża Sawczuk, Joanna Karpinska, Wojciech Miltyk
ETNOPHARMACOLOGICAL RELEVANCE: Bee products have been used in natural medicine for centuries. The largest number of scientific reports focused on the properties and therapeutic action of propolis, royal jelly, honey, bee venom and pollen. Less information can be foundabout another product of beekeeping which is drone brood. Drone brood - form of bee larvae, from which drones will develop- is considered to be waste of beekeepers. Drones are responsible for the fertilization of aqueen bee, thereby prolonging bee species...
November 1, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/30388596/androgen-treatment-effects-on-hippocampus-structure-in-boys-with-klinefelter-syndrome
#4
Lara C Foland-Ross, Judith L Ross, Allan L Reiss
Klinefelter syndrome (KS, 47,XXY) is the most common sex chromosome aneuploidy in males. A variety of complex clinical needs is associated with KS, including physical, cognitive and psychosocial impairments. Standard treatment for KS consists of androgen replacement therapy in adolescence to offset testosterone deficiency. Such treatment has a beneficial effect on the physical and behavioral manifestations of this syndrome. Whether androgen supplementation has a significant influence on the brain, however, is unknown...
October 2, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/30375514/opsin-gene-expression-regulated-by-testosterone-level-in-a-sexually-dimorphic-lizard
#5
Wen-Hsuan Tseng, Jhan-Wei Lin, Chen-Han Lou, Ko-Huan Lee, Leang-Shin Wu, Tzi-Yuan Wang, Feng-Yu Wang, Duncan J Irschick, Si-Min Lin
Expression of nuptial color is usually energetically costly, and is therefore regarded as an 'honest signal' to reflect mate quality. In order to choose a mate with high quality, both sexes may benefit from the ability to precisely evaluate their mates through optimizing visual systems which is in turn partially regulated by opsin gene modification. However, how terrestrial vertebrates regulate their color vision sensitivity is poorly studied. The green-spotted grass lizard Takydromus viridipunctatus is a sexually dimorphic lizard in which males exhibit prominent green lateral colors in the breeding season...
October 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30365552/physiological-increase-of-yolk-testosterone-level-does-not-affect-oxidative-status-and-telomere-length-in-gull-hatchlings
#6
Marco Parolini, Cristina Daniela Possenti, Andrea Romano, Manuela Caprioli, Diego Rubolini, Nicola Saino
Conditions experienced during early-life can cause the onset of oxidative stress, resulting in pervasive effects on diverse life-history traits, including lifespan. In birds, maternally-transferred egg substances may exert positive or negative influence over the offspring phenotype. Among these, testosterone can upregulate the bioavailability of certain antioxidants but simultaneously promotes the production of pro-oxidants, leading to an oxidative stress situation, which is one of the main forces causing telomere attrition However, no study has investigated the role of this androgen on telomere dynamics in birds and little is known about the effects of yolk testosterone on oxidative status in early-life of these species...
2018: PloS One
https://www.readbyqxmd.com/read/30360442/ginger-and-testosterone
#7
REVIEW
Saleem Ali Banihani
Enhancing and protecting testosterone production is one target for many scientists because of its crucial role as a primary sex hormone in males. Several in vivo trials have utilized different dietary supplements and medicinal plants to enhance testosterone production in males. Since 1991, various in-vivo, as well as basic research studies, have discovered a link between ginger ( Zingiber officinale ) and testosterone. However, such a link has not yet been collectively reviewed. This review systematically discusses and summarizes the effect of ginger and ginger extracts on testosterone...
October 22, 2018: Biomolecules
https://www.readbyqxmd.com/read/30359320/toxicological-evaluation-of-therapeutic-and-supra-therapeutic-doses-of-cellgevity%C3%A2-on-reproductive-function-and-biochemical-indices-in-wistar-rats
#8
O Awodele, W A Badru, A A Busari, O E Kale, T B Ajayi, R O Udeh, P M Emeka
BACKGROUND: The misconception about dietary supplements being safe has led many into the in-patient wards. Cellgevity® (CGV) is a Max International premiere antioxidant supplement formula used by a large population. This study evaluated the effects of therapeutic and supra-therapeutic doses of CGV on reproductive function and biochemical indices in Wistar rats. METHODS: Seventy-two Wistar rats weighing 130 ± 15.8 g were grouped into two categories (male or female) of six rats per group...
October 25, 2018: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/30352111/effects-of-casein-non-phosphopeptide-on-the-development-of-rat-muscle-analyzed-using-computed-tomography-scanning-technology
#9
Yan-Guo Shi, Na Zhang, Qing-Qi Guo, Hua-Nan Guan, Shinya Ikeda, Chang-Hui Guo, Wojciech Piekoszewski, Tatyana K Kalenik, Elwna Motkina
The effects of casein non-phosphopeptide (CNPP) on the muscle development of healthy rats and selected blood hormones levels were investigated. CT technology and the ELISA kit were employed to detect the cross-sectional area of each muscle group and blood hormone levels, respectively. The cross-sectional area of the trunk and lower limb muscles of resistance exercise group (REG) rats that were administered a high daily dose of CNPP for 50 days increased more significantly than that of the blank group rats, no exercise group (NEG) rats administered with the same daily dose of CNPP, and REG rats administered with the same daily dose of lactalbumin (P < 0...
October 23, 2018: Food & Function
https://www.readbyqxmd.com/read/30348185/combined-extracts-of-garcinia-mangostana-fruit-rind-and-cinnamomum-tamala-leaf-supplementation-enhances-muscle-strength-and-endurance-in-resistance-trained-males
#10
RANDOMIZED CONTROLLED TRIAL
Manikyeswara Rao Konda, Krishnaraju Venkata Alluri, Prason Kumar Janardhanan, Golakoti Trimurtulu, Krishanu Sengupta
BACKGROUND: A proprietary composition GMCT contains extracts of two popular Asian herbs viz., Garcinia mangostana (GM) fruit rind and Cinnamomum tamala (CT) leaf. We systematically evaluated physical performance and muscle strength enhancing ability of GMCT in a preclinical mouse model followed by a 42-days double-blind placebo controlled human trial in resistance trained adult males. METHODS: Four groups of Swiss albino mice (20-30 g body weight) (n = 6) were fed a standard laboratory diet and given Carboxymethylcellulose sodium (CMC), 150 mg/kg GMCT (GMCT-150), 300 mg/kg GMCT (GMCT-300) or 50 mg/kg Oxymetholone (OXY) via oral gavage for 21 days...
October 22, 2018: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/30340496/the-effect-of-cinnamon-on-polycystic-ovary-syndrome-in-a-mouse-model
#11
Lei Dou, Yahong Zheng, Lu Li, Xiaowei Gui, Yajuan Chen, Meng Yu, Yi Guo
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most prevalent cause of anovulatory infertility and hyperandrogenism. Evidence favors insulin resistance and compensatory hyperinsulinemia as the predominant, perhaps primary, defects in PCOS. The use of insulin-sensitizing drugs has been shown to improve both the reproductive and the metabolic aspects of PCOS. Cinnamon has been found to have insulin sensitizing effect and improve menstrual cyclicity in women with PCOS. The aim of this study was to determine the effect and mechanism of cinnamon on PCOS using a dehydroepiandrosterone (DHEA) induced PCOS mouse model...
October 19, 2018: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/30326270/the-effects-of-stress-cortisol-administration-and-cortisol-inhibition-on-black-sea-bass-centropristis-striata-sex-differentiation
#12
Kelsie A Miller, Linas W Kenter, Timothy S Breton, David L Berlinsky
Sex differentiation in many lower vertebrates (e.g. reptiles, amphibians, and fishes) can be influenced by environmental factors experienced during sensitive developmental periods. Environmental stressors, acting through cortisol, masculinize some teleost fishes during development by limiting gonadal cytochrome P450 aromatase (cyp19a1a), the enzyme that irreversibly converts testosterone to 17β-estradiol. In this study, we examined the influence of cortisol, cortisol inhibitors and a repeated, acute stressor (net-chasing) on sex differentiation in black sea bass (BSB; Centropristis striata), a protogynous hermaphroditic teleost...
October 13, 2018: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/30311248/testosterone-preserves-endothelial-function-through-regulation-of-s1p1-akt-foxo3a-signalling-pathway-in-the-rat-corpus-cavernosum
#13
Kai Cui, Rui Li, Kang Liu, Tao Wang, Jihong Liu, Ke Rao
The aim of the study was to investigate how testosterone regulating endothelial function in the corpus cavernosum of rats. A total of 32 male Sprague-Dawley (SD) rats, 10-weeks-old, were divided randomly into four groups: normal control group (Control); castration group (Castration); the other 16 rats were castrated followed by testosterone supplementation (orally) every day for 8 weeks: castration +10 mg/kg (lower dose) testosterone group (Castration +LT) and castration +20 mg/kg (high dose) testosterone group (Castration +HT)...
October 11, 2018: Andrologia
https://www.readbyqxmd.com/read/30298636/a-folic-acid-enriched-diet-attenuates-prostate-involution-in-response-to-androgen-deprivation
#14
Diya B Joseph, Anoop S Chandrashekar, Li-Fang Chu, James A Thomson, Chad M Vezina
BACKGROUND: Serum folate concentrations in the United States have risen since dietary folic acid fortification was first mandated in 1998. Although maternal folic acid offers protection against neural tube defects in conceptuses, its impact on other organ systems and life stages have not been fully examined. Here, we used a mouse model to investigate the impact of a Folic acid (FA) enriched diet on prostate homeostasis and response to androgen deprivation. METHODS: Male mice were fed a control diet (4 mg FA/kg feed) or a folic acid supplemented diet (24 mg FA/kg feed) beginning at conception and continuing through early adulthood, when mice were castrated...
October 8, 2018: Prostate
https://www.readbyqxmd.com/read/30298476/the-influence-of-caffeine-supplementation-on-resistance-exercise-a-review
#15
REVIEW
Jozo Grgic, Pavle Mikulic, Brad J Schoenfeld, David J Bishop, Zeljko Pedisic
This paper aims to critically evaluate and thoroughly discuss the evidence on the topic of caffeine supplementation when performing resistance exercise, as well as provide practical guidelines for the ingestion of caffeine prior to resistance exercise. Based on the current evidence, it seems that caffeine increases both maximal strength and muscular endurance. Furthermore, power appears to be enhanced with caffeine supplementation, although this effect might, to a certain extent, be caffeine dose- and external load-dependent...
October 8, 2018: Sports Medicine
https://www.readbyqxmd.com/read/30298116/analysis-of-the-biodegradation-of-synthetic-testosterone-and-17%C3%AE-ethynylestradiol-using-the-edible-mushroom-lentinula-edodes
#16
Bożena Muszyńska, Paweł Żmudzki, Jan Lazur, Katarzyna Kała, Katarzyna Sułkowska-Ziaja, Włodzimierz Opoka
The mycelium of Lentinula edodes produces enzymes which may degrade xenobiotics including steroid hormones. The aim of the study was to determine whether the mycelium from in vitro cultures of L. edodes are able to degrade endocrine disruptors such as testosterone and 17α-ethynylestradiol. To prove the possibility of xenobiotics degradation, cultures of L. edodes were cultivated in an Oddoux liquid medium with the addition of synthetic 17α-ethynylestradiol and synthetic testosterone. The endocrine disruptors were extracted from the mycelium and determined qualitatively by RP-HPLC...
October 2018: 3 Biotech
https://www.readbyqxmd.com/read/30273008/cordyceps-sinensis-promotes-the-growth-of-prostate-cancer-cells
#17
Ming-Wei Ma, Xian-Shu Gao, Hong-Liang Yu, Xin Qi, Shao-Qian Sun, Dian Wang
BACKGROUND: This study aims to test whether Cordyceps sinensis (CS), the most expensive Asian nutrient supplement might stimulate growth of prostate cancer cells. METHODS: Impact of CS on growth of prostate cancer was determined in vivo and in vitro. RESULTS: Firstly, the serum testosterone level was significantly elevated in mice fed CS. Prostate glands were significantly enlarged (weight index 0.53 ± 0.04 mg/g vs. 0.31 ± 0.04 mg/g, P = 0...
October 1, 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/30268884/androgens-modulate-chronic-intermittent-hypoxia-effects-on-brain-and-behavior
#18
Brina Snyder, Phong Duong, Jenny Trieu, Rebecca L Cunningham
Sleep apnea is associated with testosterone dysregulation as well as increased risk of developing neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD). A rodent model of the hypoxemic events of sleep apnea, chronic intermittent hypoxia (CIH), has been previously documented to impair cognitive function and elevate oxidative stress in male rats, while simultaneously decreasing testosterone. Therefore, androgens may modulate neuronal function under CIH. To investigate the role of androgens during CIH, male rats were assigned to one of four hormone groups: 1) gonadally intact, 2) gonadectomized (GDX), 3) GDX + testosterone (T) supplemented, or 4) GDX + dihydrotestosterone (DHT) supplemented...
October 6, 2018: Hormones and Behavior
https://www.readbyqxmd.com/read/30268730/circulating-small-non-coding-rnas-provide-new-insights-into-vitamin-k-nutrition-and-reproductive-physiology-in-teleost-fish
#19
Ignacio Fernández, Jorge M O Fernandes, Vânia P Roberto, Martina Kopp, Catarina Oliveira, Marta F Riesco, Jorge Dias, Cymon J Cox, M Leonor Cancela, Elsa Cabrita, Paulo Gavaia
BACKGROUND: Vitamin K (VK) is a fat-soluble vitamin known for its essential role in blood coagulation, but also on other biological processes (e.g. reproduction, brain and bone development) have been recently suggested. Nevertheless, the molecular mechanisms behind its particular function on reproduction are not yet fully understood. METHODS: The potential role of VK on reproduction through nutritional supplementation in Senegalese sole (Solea senegalensis) was assessed by gonadal maturation and 11-ketosterone, testosterone and estriol plasma levels when fed with control or VK supplemented (1250 mg kg-1 of VK1 ) diets along a six month trial...
September 27, 2018: Biochimica et biophysica acta. General subjects
https://www.readbyqxmd.com/read/30261076/resistance-training-and-l-arginine-supplementation-are-determinant-in-genomic-stability-cardiac-contractility-and-muscle-mass-development-in-rats
#20
Giuseppe Potrick Stefani, Bruna Marmett, Jadson Pereira Alves, Gabriella Berwig Möller, Thiago Gomes Heck, Matias Nunes Frizzo, Marlise Di Domenico, Gabriela Almeida Motta, Pedro Dal Lago, Ramiro Barcos Nunes, Cláudia Ramos Rhoden
L-arginine supplementation has been related to increased maximum strength and improvement of hemodynamic parameters in several diseases. The aim of our study was to evaluate the effect of L-arginine supplementation and resistance training on muscle mass, hemodynamic function and DNA damage in healthy rats subjected to a low-arginine concentration diet. Twenty three Wistar rats (290-320g) were divided into 4 groups: Sedentary (SED-Arg, n = 6), Sedentary+Arg (SED+Arg, n = 6), Resistance Training (RT-Arg, n = 5), Resistance Training+Arg (RT+Arg, n = 6)...
2018: PloS One
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