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Implementation science

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https://www.readbyqxmd.com/read/28231328/integrating-the-sd-clue-s-and-invest-models-into-assessment-of-oasis-carbon-storage-in-northwestern-china
#1
Youjia Liang, Lijun Liu, Jiejun Huang
Spatio-temporal integrated assessment of land-use change impacts on carbon storage services is a new and important research field in land science and landscape ecology. The objective of this paper is to use an integrated SD-CLUE-S and InVEST model to simulate and predict land-use changes impacts during 2000-2018 on carbon storage at pixel and regional scales in the Zhangye oasis, Northwest China. The SD-CLUE-S model was used to simulate land-use change, and three land-use scenarios (current trend, moderate protection, and strict protection) were defined in collaboration with oasis socioeconomic development and ecological environment conservation by local government...
2017: PloS One
https://www.readbyqxmd.com/read/28230868/tuning-calcium-biosensors-with-a-single-site-mutation-structural-dynamics-insights-from-femtosecond-raman-spectroscopy
#2
Sean R Tachibana, Longteng Tang, Yanli Wang, Liangdong Zhu, Weimin Liu, Chong Fang
Fluorescent protein biosensors are popular reporters for biological processes and life sciences, but their fundamental working mechanisms remain unclear. To characterize the functional fluorescence events on their native timescales, we implemented wavelength-tunable femtosecond stimulated Raman spectroscopy (FSRS) to shed light on a blue-green emission-ratiometric fluorescent protein based Ca(2+) biosensor with a single Pro377Arg mutation. The transient Raman modes of the embedded chromophore from ca. 1000-1650 cm(-1) exhibit characteristic intensity and frequency dynamics which infer the underlying atomic motions and photochemical reaction stages...
February 23, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28230815/conceptual-foundations-of-systems-biology-explaining-complex-cardiac-diseases
#3
REVIEW
George E Louridas, Katerina G Lourida
Systems biology is an important concept that connects molecular biology and genomics with computing science, mathematics and engineering. An endeavor is made in this paper to associate basic conceptual ideas of systems biology with clinical medicine. Complex cardiac diseases are clinical phenotypes generated by integration of genetic, molecular and environmental factors. Basic concepts of systems biology like network construction, modular thinking, biological constraints (downward biological direction) and emergence (upward biological direction) could be applied to clinical medicine...
February 21, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28229306/behavioral-and-social-sciences-at-the-national-institutes-of-health-adoption-of-research-findings-in-health-research-and-practice-as-a-scientific-priority
#4
William T Riley
The National Institutes of Health's Office of Behavioral and Social Sciences Research (OBSSR) recently released its Strategic Plan for 2017 to 2021. This plan highlights three scientific priorities: (1) improve the synergy of basic and applied behavioral and social sciences research, (2) enhance and promote the research infrastructure, methods, and measures needed to support a more cumulative and integrated approach to behavioral and social sciences research, and (3) facilitate the adoption of behavioral and social sciences research findings in health research and in practice...
February 22, 2017: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/28227254/a-data-science-approach-for-quantifying-spatio-temporal-effects-to-graft-failures-in-organ-transplantation
#5
Diego Pinheiro, Farag Hamad, Martin Cadeiras, Ronaldo Menezes, Nezamoddin Nezamoddini-Kachouie, Diego Pinheiro, Farag Hamad, Martin Cadeiras, Ronaldo Menezes, Nezamoddin Nezamoddini-Kachouie, Farag Hamad, Martin Cadeiras, Diego Pinheiro, Ronaldo Menezes, Nezamoddin Nezamoddini-Kachouie
The transplantation of solid organs is one of the most important accomplishments of modern medicine. Yet, organ shortage is a major public health issue; 8,000 people died while waiting for an organ in 2014. Meanwhile, the allocation system currently implemented can lead to organs being discarded and the medical community still investigates factors that affects early graft failure such as distance and ischemic time. In this paper, we investigate early graft failure under a spatio-temporal perspective using a data science unified approach for all six organs that is based on complementary cumulative analysis of both distance and ischemic time...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225163/transforming-conservation-science-and-practice-for-a-post-normal-world
#6
REVIEW
Matthew J Colloff, Sandra Lavorel, Lorrae E van Kerkhoff, Carina A Wyborn, Ioan Fazey, Russell Gorddard, Georgina M Mace, Wendy B Foden, Michael Dunlop, I Colin Prentice, John Crowley, Paul Leadley, Patrick Degeorges
In this essay we highlight issues to consider when reframing conservation objectives and outcomes in the context of global change. We discuss (1) new framings of the links between ecosystems and society; (2) new relationships and roles for conservation science; (3) new models of how conservation links to society and social change and (4) new approaches for implementing adaptation for conservation outcomes. We argue that reframing conservation objectives requires conservation scientists and practitioners to implement approaches that are no longer constrained by discipline and sectoral boundaries, geopolitical polarities, or technical problematisation...
February 22, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28222798/fracture-risk-in-dialysis-and-kidney-transplanted-patients-a-protocol-for-systematic-review-and-meta-analysis
#7
Aboubacar Sidibé, Lynne Moore, Sonia Jean, Fabrice Mac-Way
BACKGROUND: Chronic kidney disease (CKD) is associated with an increased risk of fracture and cardiovascular mortality. The risk of fracture in hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (KT) is higher when compared to the general population. However, uncertainties remain about which group has the highest risk of fracture. We aim to identify the risk of fracture and cardiovascular mortality post-fracture in HD compared to PD or KT and in PD compared to KT population...
February 22, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28222735/advancing-gender-equality-through-the-athena-swan-charter-for-women-in-science-an-exploratory-study-of-women-s-and-men-s-perceptions
#8
Pavel V Ovseiko, Alison Chapple, Laurel D Edmunds, Sue Ziebland
BACKGROUND: While in the United Kingdom, Ireland, and Australia, higher education and research institutions are widely engaged with the Athena SWAN Charter for Women in Science to advance gender equality, empirical research on this process and its impact is rare. This study combined two data sets (free- text comments from a survey and qualitative interviews) to explore the range of experiences and perceptions of participation in Athena SWAN in medical science departments of a research-intensive university in Oxford, United Kingdom...
February 21, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28222516/intelligent-assistive-technology-for-alzheimer-s-disease-and-other-dementias-a-systematic-review
#9
Marcello Ienca, Jotterand Fabrice, Bernice Elger, Maurizio Caon, Alessandro Scoccia Pappagallo, Reto W Kressig, Tenzin Wangmo
Intelligent assistive technologies (IATs) have the potential of offering innovative solutions to mitigate the global burden of dementia and provide new tools for dementia care. While technological opportunities multiply rapidly, clinical applications are rare as the technological potential of IATs remains inadequately translated into dementia care. In this article, the authors present the results of a systematic review and the resulting comprehensive technology index of IATs with application in dementia care...
February 7, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28221969/development-and-validation-of-pathogen-environmental-monitoring-programs-for-small-cheese-processing-facilities
#10
Sarah M Beno, Matthew J Stasiewicz, Alexis D Andrus, Robert D Ralyea, David J Kent, Nicole H Martin, Martin Wiedmann, Kathryn J Boor
Pathogen environmental monitoring programs (EMPs) are essential for food processing facilities of all sizes that produce ready-to-eat food products exposed to the processing environment. We developed, implemented, and evaluated EMPs targeting Listeria spp. and Salmonella in nine small cheese processing facilities, including seven farmstead facilities. Individual EMPs with monthly sample collection protocols were designed specifically for each facility. Salmonella was detected in only one facility, with likely introduction from the adjacent farm indicated by pulsed-field gel electrophoresis data...
December 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28219446/effective-knowledge-translation-approaches-and-practices-in-indigenous-health-research-a-systematic-review-protocol
#11
Melody E Morton Ninomiya, Donna Atkinson, Simon Brascoupé, Michelle Firestone, Nicole Robinson, Jeff Reading, Carolyn P Ziegler, Raglan Maddox, Janet K Smylie
BACKGROUND: Effective knowledge translation (KT) is critical to implementing program and policy changes that require shared understandings of knowledge systems, assumptions, and practices. Within mainstream research institutions and funding agencies, systemic and insidious inequities, privileges, and power relationships inhibit Indigenous peoples' control, input, and benefits over research. This systematic review will examine literature on KT initiatives in Indigenous health research to help identify wise and promising Indigenous KT practices and language in Canada and abroad...
February 20, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28219100/-current-developments-of-the-interdisciplinary-subject-rehabilitation-physical-medicine-naturopathic-treatment-in-the-german-medical-faculties-results-of-the-dgrw-faculty-survey-in-2015
#12
S Schmidt, C Bergelt, R Deck, G Krischak, M Morfeld, M Michel, S R Schwarzkopf, K Spyra, S Walter, W Mau
To ascertain the current development of the rehabilitation-related medical teaching in the interdisciplinary subject Rehabilitation, Physical Medicine, Naturopathic Treatment (Q12) regarding its execution, content, exams and evaluation of teaching at the Medical Faculties the German Society of Rehabilitation Science conducted another faculty survey in 2015. Representatives of all degree courses of human medicine in German Universities (n=41) received a pseudonymised standardised questionnaire in summer 2015...
February 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/28218340/world-health-organization-global-disability-action-plan-the-mongolian-perspective
#13
Fary Khan, Bhasker Amatya, Baljnnyam Avirmed, Yoon Kyoung Yi, Batchimeg Shirmen, Geoff Abbott, Mary P Galea
OBJECTIVE: To provide an update on disability and rehabilitation in Mongolia, and to identify potential barriers and facilitators for implementation of the World Health Organization (WHO) Global Disability Action Plan (GDAP). METHODS: A 4-member rehabilitation team from the Royal Melbourne Hospital conducted an intensive 6-day workshop at the Mongolian National University of Medical Sciences, for local healthcare professionals (n = 77) from medical rehabilitation facilities (urban/rural, public/private) and non-governmental organizations...
February 16, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28217450/understanding-the-cellular-basis-and-pathophysiology-of-peyronie-s-disease-to-optimize-treatment-for-erectile-dysfunction
#14
REVIEW
Jeffrey Campbell, Raidh Alzubaidi
Erectile dysfunction (ED) is a common condition that significantly impacts a man's physical and psychological well-being. ED is often associated with Peyronie's disease (PD), which is an abnormal curvature of the penis. Delayed treatment of or surgical invention for PD often results in ED and therefore unsatisfied patients. The pathophysiology of PD is incompletely understood, but has been studied extensively and based on our current understanding of PD physiology, many medical treatment options have been proposed...
February 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28215389/dissemination-and-implementation-science-training-needs-insights-from-practitioners-and-researchers
#15
Rachel G Tabak, Margaret M Padek, Jon F Kerner, Kurt C Stange, Enola K Proctor, Maureen J Dobbins, Graham A Colditz, David A Chambers, Ross C Brownson
INTRODUCTION: Dissemination and implementation research training has great potential to improve the impact and reach of health-related research; however, research training needs from the end user perspective are unknown. This paper identifies and prioritizes dissemination and implementation research training needs. METHODS: A diverse sample of researchers, practitioners, and policymakers was invited to participate in Concept Mapping in 2014-2015. Phase 1 (Brainstorming) gathered participants' responses to the prompt: To improve the impact of research evidence in practice and policy settings, a skill in which researchers need more training is… The resulting statement list was edited and included subsequent phases...
March 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28215386/learning-about-and-using-research-evidence-among-public-health-practitioners
#16
Rebekah R Jacob, Peg M Allen, Linda J Ahrendt, Ross C Brownson
INTRODUCTION: Funders and accreditation standards increasingly call on state and local public health agencies to use the best available science. Using research evidence is a key process in practicing evidence-based decision making (EBDM). This study explored preferences for and uses of research evidence, and examined correlates regarding frequency of use. METHODS: In 2014, eligible staff from 12 state health departments and their partnering agencies were invited to complete an online self-report questionnaire and achieved an 82% response rate (1,237/1,509)...
March 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28215385/research-to-practice-implementing-physical-activity-recommendations
#17
Sally M Davis, Theresa H Cruz, Richard L Kozoll
INTRODUCTION: Dissemination and implementation science focuses on bridging the gap between research and practice. The Community Preventive Services Task Force published recommendations for increasing physical activity based on scientific review and consensus. Little research on the dissemination and implementation of these recommendations has been conducted in under-represented populations at high risk for inactivity and chronic disease. METHODS: Partnering with one rural community (beta site), the University of New Mexico Prevention Research Center studied the translation of Community Preventive Services Task Force recommendations to practice...
March 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28215384/enhance-%C3%A2-fitness-dissemination-and-implementation-2010-2015-a-scoping-review
#18
Miruna G Petrescu-Prahova, Thomas J Eagen, Sarah L Fishleder, Basia Belza
INTRODUCTION: Physical activity has many benefits for older adult physical and mental health. Enhance(®)Fitness (EF) is an evidence-based group exercise program delivered by community-based organizations. The purpose of this study was to review recent evidence on the dissemination and implementation of EF. METHODS: A scoping review of qualitative and quantitative studies with EF as main focus was conducted. CINAHL, PubMed, PubMed Central, SCOPUS, Web of Science, PsycINFO, and Google Scholar were searched between October and November 2015 for data-based studies on EF published in 2010-2015...
March 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28215373/prevention-research-center-collaborations-with-state-departments-of-health-washington-state
#19
EDITORIAL
Peggy A Hannon, Thuy T Vu, Patricia Migliore Santiago, Pama Joyner, Caitlin Mason, Jeffrey R Harris
State health departments and Prevention Research Centers (PRCs) have complementary mandates and expertise important to improving population health. State health departments manage and administer numerous programs with broad population reach. PRCs bridge dissemination and implementation research and public health practice to improve health programming and outcomes. This paper describes the 15-year partnership between the Washington State Department of Health and the PRC at the University of Washington. Through this partnership, the Washington State Department of Health increases their research and evaluation capacity by working with the University of Washington PRC, and the University of Washington PRC receives opportunities to apply evidence in a variety of practice settings, expand the reach of their research-tested programs to new populations, and form new partnerships...
March 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28215371/impact-of-the-cancer-prevention-and-control-research-network-accelerating-the-translation-of-research-into-practice
#20
EDITORIAL
Kurt M Ribisl, Maria E Fernandez, Daniela B Friedman, Peggy A Hannon, Jennifer Leeman, Alexis Moore, Lindsay Olson, Marcia Ory, Betsy Risendal, Laura Sheble, Vicky M Taylor, Rebecca S Williams, Bryan J Weiner
The Cancer Prevention and Control Research Network (CPCRN) is a thematic network dedicated to accelerating the adoption of evidence-based cancer prevention and control practices in communities by advancing dissemination and implementation science. Funded by the Centers for Disease Control and Prevention and National Cancer Institute, CPCRN has operated at two levels: Each participating network center conducts research projects with primarily local partners as well as multicenter collaborative research projects with state and national partners...
March 2017: American Journal of Preventive Medicine
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