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https://www.readbyqxmd.com/read/28367045/neutrophil-to-lymphocyte-ratio-in-patients-with-nonarteritic-anterior-ischemic-optic-neuropathy
#1
Alime Gunes, Musa Yigit, Levent Tok, Ozlem Tok
PURPOSE: To evaluate the neutrophil to lymphocyte ratio (NLR) in patients with nonarteritic anterior ischemic optic neuropathy (NAION). METHODS: We investigated 112 subjects comprising 56 patients with NAION and 56 healthy controls at Süleyman Demirel University. Complete blood count, demographic, and clinic data from NAION patients were evaluated in this study. The NLR was calculated in all individuals and compared between the patient and control groups. Cut-off values were also determined...
April 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28347664/venestatin-a-ca-binding-protein-from-the-parasitic-nematode-strongyloides-venezuelensis-is-involved-in-the-larval-migration-process
#2
Daigo Tsubokawa, Takeshi Hatta, Taisei Kikuchi, Hiroki Maeda, Fusako Mikami, M Abdul Alim, Haruhiko Maruyama, Naotoshi Tsuji
The secretory EF-hand Ca(++)-binding proteins act as calcium signaling molecules for control of cell functions, but those proteins from parasitic helminths are poorly understood. Here, we have identified and characterized an EF-hand Ca(++)-binding protein from the rodent nematode, Strongyloides venezuelensis, termed 'venestatin', which is highly conserved in Strongyloides spp. Canonical two EF-hand domains and a signal peptide are present in venestatin. A gel mobility shift assay and Ruthenium red staining indicated that the recombinant venestatin possesses binding ability with Ca(++) ions...
March 24, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28345581/potential-of-biosynthesized-silver-nanoparticles-using-stenotrophomonas-sp-bhu-s7-mtcc-5978-for-management-of-soil-borne-and-foliar-phytopathogens
#3
Sandhya Mishra, Braj Raj Singh, Alim H Naqvi, H B Singh
Stenotrophomonas sp. is emerging as a popular microbe of global concern with various potential ecological roles. Biosynthesis of gold and silver nanoparticles (AgNPs) using this bacterial strain has shown promising applications in life sciences. However, there is no report on efficient agricultural applications of biosynthesized AgNPs using Stenotrophomonas sp. In this regard, successful biosynthesis of AgNPs using Stenotrophomonas sp. BHU-S7 (MTCC 5978) was monitored by Uv-visible spectrum showing surface plasmon resonance (SPR) peak at 440 nm...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28342364/therapeutic-effect-of-quercetin-in-collagen-induced-arthritis
#4
Nagaraja Haleagrahara, Socorro Miranda-Hernandez, Md Abdul Alim, Linda Hayes, Guy Bird, Natkunam Ketheesan
Quercetin, a bioactive flavonoid with anti-inflammatory, immunosuppressive, and protective properties, is a potential agent for the treatment of rheumatoid arthritis (RA). Collagen-induced arthritis (CIA) is the most commonly used animal model for studying the pathogenesis of RA. This study analysed the therapeutic role of quercetin in collagen-induced arthritis in C57BL/6 mice. The animals were allocated into five groups that were subjected to the following treatments: negative (untreated) control, positive control (arthritis-induced), arthritis+methotrexate, arthritis+quercetin, and arthritis+methotrexate+quercetin...
March 22, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28340864/multi-dimensional-scores-to-predict-mortality-in-patients-with-idiopathic-pulmonary-fibrosis-undergoing-lung-transplantation-assessment
#5
Jolene H Fisher, Faris Al-Hejaili, Sonja Kandel, Alim Hirji, Shane Shapera, Marco Mura
BACKGROUND: The heterogeneous progression of idiopathic pulmonary fibrosis (IPF) makes prognostication difficult and contributes to high mortality on the waitlist for lung transplantation (LTx). Multi-dimensional scores (Composite Physiologic index [CPI], [Gender-Age-Physiology [GAP]; RIsk Stratification scorE [RISE]) demonstrated enhanced predictive power towards outcome in IPF. The lung allocation score (LAS) is a multi-dimensional tool commonly used to stratify patients assessed for LTx...
April 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28337421/zygomatic-miniplates-for-skeletal-anchorage-in-orthopedic-correction-of-class-iii-malocclusion-a-controlled-clinical-trial
#6
Erdal Bozkaya, Alime Sema Yüksel, Süleyman Bozkaya
OBJECTIVE: To evaluate the effects of facemask therapy, which was anchored from the zygomatic buttresses of the maxilla by using two miniplates, in skeletal Class III patients with maxillary deficiency. METHODS: Eighteen skeletal Class III patients (10 girls and 8 boys; mean age, 11.4 ± 1.28 years) with maxillary deficiency were treated using miniplate-anchored facemasks, and their outcomes were compared with those of a Class III control group (9 girls and 9 boys; mean age, 10...
March 2017: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/28303062/perception-and-attitude-of-medical-doctors-in-dhaka-bangladesh-with-regard-to-ayurvedic-medicine
#7
Yoshitoku Yoshida, Md Abdul Alim, Zakia Alam, Mohammad Asaduzzaman, Yasuko Yoshida, Shahabuddin Manikdrs
The World Health Organization (WHO) Traditional Medicine Strategy (2014-2023) aimed to help member states promote the safe and effective use of traditional medicine. While economic conditions have markedly improved in Bangladesh, the country is experiencing significant public health problems. Because of limited medical resources, there is a strong incentive to enhance complementary and alternative medicine usage in Bangladesh. Therefore, this study aimed to confirm the perceptions and attitudes of medical doctors (MDs) in Dhaka, Bangladesh, with regard to Ayurvedic medicine (AM)...
February 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28299414/photobiomodulation-induced-changes-in-a-monkey-model-of-parkinson-s-disease-changes-in-tyrosine-hydroxylase-cells-and-gdnf-expression-in-the-striatum
#8
Nabil El Massri, Ana P Lemgruber, Isobel J Rowe, Cécile Moro, Napoleon Torres, Florian Reinhart, Claude Chabrol, Alim-Louis Benabid, John Mitrofanis
Intracranial application of red to infrared light, known also as photobiomodulation (PBM), has been shown to improve locomotor activity and to neuroprotect midbrain dopaminergic cells in rodent and monkey models of Parkinson's disease. In this study, we explored whether PBM has any influence on the number of tyrosine hydroxylase (TH)(+)cells and the expression of GDNF (glial-derived neurotrophic factor) in the striatum. Striatal sections of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-treated mice and monkeys and 6-hydroxydopamine (6OHDA)-lesioned rats that had PBM optical fibres implanted intracranially (or not) were processed for immunohistochemistry (all species) or western blot analysis (monkeys)...
March 15, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28265722/mr-imaging-of-carotid-webs
#9
Mari E Boesen, Prasanna Venkatesan Eswaradass, Dilip Singh, Alim P Mitha, Mayank Goyal, Richard Frayne, Bijoy K Menon
PURPOSE: We propose a magnetic resonance (MR) imaging protocol for the characterization of carotid web morphology, composition, and vessel wall dynamics. The purpose of this case series was to determine the feasibility of imaging carotid webs with MR imaging. METHODS: Five patients diagnosed with carotid web on CT angiography were recruited to undergo a 30-min MR imaging session. MR angiography (MRA) images of the carotid artery bifurcation were acquired. Multi-contrast fast spin echo (FSE) images were acquired axially about the level of the carotid web...
March 6, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28265528/resident-development-via-progress-testing-and-test-marking-an-innovation-and-program-evaluation
#10
Karen Schiff, D Josh Williams, Alim Pardhan, Ian Preyra, Shelly-Anne Li, Teresa Chan
INTRODUCTION: Since 2008, the McMaster University Royal College Emergency Medicine residency training program has run practice Short Answer Question (SAQ) examinations to help residents test their knowledge and gain practice in answering exam-style questions. However, marking this type of SAQ exam is time-consuming. METHODS: To help address this problem, we require that senior residents help mark at least one exam per year alongside faculty members. Examinees' identities are kept anonymous by assigning a random number to each resident, which is only decoded after marking...
January 23, 2017: Curēus
https://www.readbyqxmd.com/read/28255469/differential-diagnosis-of-parotid-lipoma-in-a-breast-ca-patient
#11
Melda Misirlioglu, Yagmur Yilmaz Akyil, Mehmet Zahit Adisen, Alime Okkesim
Lipomas are common benign tumors usually detected on the torso, neck, upper thighs, and upper arms. However, they are rarely found in the parotid gland region. Because of their rarity at this site, they are not often considered in the differential diagnosis of parotid tumors. This report describes a rare case of a lipoma in the superficial lobe of parotid gland. A 71-year-old female patient admitted to our department complaining about swelling and pain in the posterior area of the left mandibular region since one month...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28251195/chemical-characterization-of-a-novel-polysaccharide-askp-1-from-artemisia-sphaerocephala-krasch-seed-and-its-macrophage-activation-via-mapk-pi3k-akt-and-nf-%C3%AE%C2%BAb-signaling-pathways-in-raw264-7-cells
#12
Daoyuan Ren, Dehui Lin, Aamina Alim, Quan Zheng, Xingbin Yang
The aim of this study was to investigate the molecular mechanism underlying the immunomodulatory effect of the purified Artemisia sphaerocephala Krasch seed polysaccharide (ASKP-1) in RAW264.7 macrophages. Chemical characteristic analysis revealed that ASKP-1 consisted of 14.1% mannose, 56.9% glucose and 19.6% galactose with the average molecular weight of 9.08 × 10(5) Da and the mixed glycan backbone structure containing 1→4)-Glcp (39.8%), 1→6)-Galp (18.8%), 1→3,6)-Manp (19.6%), 1→)-Glcp (10.8%), 2→6)-Manp (4...
March 2, 2017: Food & Function
https://www.readbyqxmd.com/read/28231181/the-determinants-of-organic-vegetable-purchasing-in-jabodetabek-region-indonesia
#13
Alim Setiawan Slamet, Akira Nakayasu, Hu Bai
Over the last few years, the global market of organic vegetables has grown. This is due to increased consumer concern regarding environmental and health issues, especially for food products. This study aims to examine factors that influence consumer behavior in purchasing organic vegetables. In this study, data were obtained from household surveys conducted in the Jabodetabek region (Greater Jakarta) from February to March 2015. Descriptive analysis, factor analysis, and a binary logit model were used to analyze the data...
December 7, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28217947/mechanism-of-capsaicin-inhibition-of-aldose-reductase-activity
#14
Zuhal Alim, Namık Kilinc, Bulent Sengul, Sukru Beydemir
Aldose reductase (AR) inhibitors play a vital importance as a potential therapeutic and preventive medicine when it comes to hyperglycemia associated diabetic complications. Additionally, capsaicin is used as a food additive and a drug in a number of diverse clinical trials. The aim of this study is to determine the in vitro inhibition behavior of capsaicin on AR enzyme activity, which was obtained from different rat tissues (heart, kidney, liver, and brain). We showed that AR was inhibited by capsaicin in the micromolar range and noncompetitive manner in all of the tissues...
February 20, 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/28185662/alphab-crystallin-expression-correlates-with-aging-deficits-in-the-peripheral-nervous-system
#15
Erin-Mai F Lim, Alim Musa, Ariana Frederick, Shalina S Ousman
In an effort to identify factors that contribute to age-related deficits in the undamaged and injured peripheral nervous system (PNS), we noted that Brady and colleagues found that mice null for a small heat shock protein called alphaB-crystallin (αBC) developed abnormalities early in life that are reminiscent of aging pathologies. Because of our observation that αBC protein levels markedly reduce as wild-type mice age, we investigated whether the crystallin plays a role in modulating age-related deficits in the uninjured and damaged PNS...
May 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28173579/mesial-extratemporal-lobe-epilepsy-clinical-features-and-surgical-strategies
#16
Tom Theys, Lorella Minotti, Laura Tassi, Giorgio Lo Russo, Alim-Louis Benabid, Philippe Kahane, Stephan Chabardès
No abstract text is available yet for this article.
February 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28134056/statistical-analysis-plan-for-the-family-led-rehabilitation-after-stroke-in-india-attend-trial-a-multicenter-randomized-controlled-trial-of-a-new-model-of-stroke-rehabilitation-compared-to-usual-care
#17
Laurent Billot, Richard I Lindley, Lisa A Harvey, Pallab K Maulik, Maree L Hackett, Gudlavalleti Vs Murthy, Craig S Anderson, Bindiganavale R Shamanna, Stephen Jan, Marion Walker, Anne Forster, Peter Langhorne, Shweta J Verma, Cynthia Felix, Mohammed Alim, Dorcas Bc Gandhi, Jeyaraj Durai Pandian
Background In low- and middle-income countries, few patients receive organized rehabilitation after stroke, yet the burden of chronic diseases such as stroke is increasing in these countries. Affordable models of effective rehabilitation could have a major impact. The ATTEND trial is evaluating a family-led caregiver delivered rehabilitation program after stroke. Objective To publish the detailed statistical analysis plan for the ATTEND trial prior to trial unblinding. Methods Based upon the published registration and protocol, the blinded steering committee and management team, led by the trial statistician, have developed a statistical analysis plan...
February 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28133658/on-the-twinning-in-znpd
#18
Dennis C A Ivarsson, Ulrich Burkhardt, Marc Heggen, Alim Ormeci, Marc Armbrüster
The intermetallic compound ZnPd has demonstrated excellent catalytic properties in methanol steam reforming. While it is known that defects and microstructures influence the catalytic properties, little is known about the defects occurring in ZnPd. Due to recent advances in synthetic methods, coarse-grained ZnPd samples are accessible. This enables the detection and investigation of twinning in ZnPd by studying the twinned regions from the macroscopic scale by polarised light and electron backscattering diffraction (EBSD) down to the atomic scale by high-resolution transmission electron microscopy (HR-TEM)...
January 30, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28123195/pharmacists-in-a-complex-chronic-disease-management-clinic
#19
Uzma Alim, Nyanza Austin-Bishop, Ginny Cummings
No abstract text is available yet for this article.
November 2016: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/28122008/compromised-neurotrophic-and-angiogenic-regenerative-capability-during-tendon-healing-in-a-rat-model-of-type-ii-diabetes
#20
Aisha S Ahmed, Jian Li, Alim M D Abdul, Mahmood Ahmed, Claes-Göran Östenson, Paul T Salo, Carolyn Hewitt, David A Hart, Paul W Ackermann
Metabolic diseases such as diabetes mellitus type-II (DM-II) may increase the risk of suffering painful connective tissue disorders and tendon ruptures. The pathomechanisms, however, by which diabetes adversely affects connective tissue matrix metabolism and regeneration, still need better definition. Our aim was to study the effect of DM-II on expressional changes of neuro- and angiotrophic mediators and receptors in intact and healing Achilles tendon. The right Achilles tendon was transected in 5 male DM-II Goto-Kakizaki (GK) and 4 age-matched Wistar control rats...
2017: PloS One
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