Katsushi Tajima, Shuhei Okuyama, Taichi Terada, Daisuke Akaneya, Ryuichiro Hori, Shuichi Abe, Tsuguo Honma, Riko Tsumanuma, Eijiro Omoto, Junko Ito, Tohru Gonoi
BACKGROUND Nocardia infections have rarely been reported in hematopoietic stem cell transplantation (HSCT) patients, who usually receive the prophylactic use of sulfamethoxazole/trimethoprim (ST) against Pneumocystis jiroveci. However, the ST prophylaxis, sensitive to Nocardia species, sometimes induces renal toxicities. Therefore, alternative prophylactic or therapeutic drugs are required for nocardiosis in HSCT patients. CASE REPORT A 34-year-old Japanese man with acute mixed phenotypic leukemia with t(9; 22) received allogenic peripheral blood HSCT from a haplo-identical sibling donor...
June 15, 2021: American Journal of Case Reports