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https://www.readbyqxmd.com/read/28719494/hockey-fans-in-training-a-pilot-pragmatic-randomized-controlled-trial
#1
Robert J Petrella, Dawn P Gill, Guangyong Zou, Ashleigh De Cruz, Brendan Riggin, Cassandra Bartol, Karen Danylchuk, Kate Hunt, Sally Wyke, Cindy M Gray, Christopher Bunn, Merrick Zwarenstein
INTRODUCTION: Hockey Fans in Training (Hockey FIT) is a gender-sensitized weight loss and healthy lifestyle program. We investigated: 1) feasibility of recruiting and retaining overweight and obese men into a pilot pragmatic randomized controlled trial; and 2) potential for Hockey FIT to lead to weight loss and improvements in other outcomes at 12 weeks and 12 months. METHODS: Male fans of 2 ice hockey teams (35-65 years; body-mass index ≥28 kg/m) located in Ontario (Canada) were randomized to intervention (Hockey FIT) or comparator (Wait-list Control)...
July 17, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28714405/emerging-targets-to-relieve-fat-stress-induced-liver-diseases-udca-tocotrienol-%C3%AF-3-pufas-and-igy-targeted-npc1l1-cholesterol-transporter
#2
Ji-Young Cha, Jong-Min Park, Ho-Jae Lee, Jin-Sik Bae, Young-Min Han, Byung-Chul Oh, Kwang Hyun Ko, Ki-Baik Hahm
Fat stress-induced liver disease is a hepatic manifestation of metabolic syndrome initiated by excess fat accumulation and encompasses a wide spectrum of diseases from non-alcoholic fatty liver disease to non-alcoholic steatohepatitis, a precursor lesion progressing to more aggressive liver cirrhosis and hepatocellular carcinoma. Although the incidence of these fat stress-induced liver diseases is rapidly increasing worldwide in parallel with the growing epidemics of obesity and metabolic diseases, its exact pathogenesis is not well defined...
July 14, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28710665/physical-exercise-reduces-pyruvate-carboxylase-pcb-and-contributes-to-hyperglycemia-reduction-in-obese-mice
#3
Vitor Rosetto Muñoz, Rafael Calais Gaspar, Barbara Moreira Crisol, Guilherme Pedron Formigari, Marcella Ramos Sant'Ana, José Diego Botezelli, Rodrigo Stellzer Gaspar, Adelino S R da Silva, Dennys Esper Cintra, Leandro Pereira de Moura, Eduardo Rochete Ropelle, José Rodrigo Pauli
The present study evaluated the effects of exercise training on pyruvate carboxylase protein (PCB) levels in hepatic tissue and glucose homeostasis control in obese mice. Swiss mice were distributed into three groups: control mice (CTL), fed a standard rodent chow; diet-induced obesity (DIO), fed an obesity-inducing diet; and a third group, which also received an obesity-inducing diet, but was subjected to an exercise training protocol (DIO + EXE). Protocol training was carried out for 1 h/d, 5 d/wk, for 8 weeks, performed at an intensity of 60% of exhaustion velocity...
July 14, 2017: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/28710205/effect-of-interdisciplinary-care-on-weight-loss-a-randomised-controlled-trial
#4
Linda C Tapsell, Maureen Lonergan, Marijka J Batterham, Elizabeth P Neale, Allison Martin, Rebecca Thorne, Frank Deane, Gregory Peoples
OBJECTIVE: To determine the effectiveness of a novel interdisciplinary treatment compared with usual care on weight loss in overweight and obese adult volunteers. DESIGN: Single blinded controlled trial. Participants randomly assigned to usual care (C, general guideline-based diet and exercise advice), intervention (I, interdisciplinary protocol) or intervention + a healthy food supplement (30 g walnuts/day) (IW). SETTING: Community based study, Illawarra region, south of Sydney, Australia...
July 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28709772/physical-health-promotion-in-patients-with-functional-psychoses-receiving-community-psychiatric-services-results-of-the-physico-dsm-vr-study
#5
Elena Bonfioli, Maria Angela Mazzi, Loretta Berti, Lorenzo Burti
OBJECTIVES: Psychotic patients have poorer health behaviours, including poor diets and sedentary lifestyles increasing their risk for obesity, diabetes, hypertension, and dyslipidaemia, and tend to have a shorter life expectancy as compared to nonpsychiatric populations. Lifestyle intervention programmes that target modifiable risk factors in such patients have produced uneven results. The objective was to evaluate the efficacy of a package of health promotion strategies to improve diet and physical exercise in psychotic patients...
July 11, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28708479/the-essential-role-of-exercise-in-the-management-of-type-2-diabetes
#6
REVIEW
John P Kirwan, Jessica Sacks, Stephan Nieuwoudt
Exercise is typically one of the first management strategies advised for patients newly diagnosed with type 2 diabetes. Together with diet and behavior modification, exercise is an essential component of all diabetes and obesity prevention and lifestyle intervention programs. Exercise training, whether aerobic or resistance training or a combination, facilitates improved glucose regulation. High-intensity interval training is also effective and has the added benefit of being very time-efficient. While the efficacy, scalability, and affordability of exercise for the prevention and management of type 2 diabetes are well established, sustainability of exercise recommendations for patients remains elusive...
July 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28708478/diabetes-with-obesity-is-there-an-ideal-diet
#7
REVIEW
Zahrae Sandouk, M Cecilia Lansang
For individuals who are overweight or obese, weight loss is effective in preventing and improving the management of type 2 diabetes. Together with other lifestyle factors like exercise and behavior modification, diet plays a central role in achieving weight loss. Diets vary based on the type and amount of carbohydrate, fat, and protein consumed to meet daily caloric intake goals. A number of popular diets are reviewed as well as studies evaluating the effect of various diets on weight loss, diabetes, and cardiovascular risk factors...
July 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28708468/a-botanical-composition-from-morus-alba-ilex-paraguariensis-and-rosmarinus-officinalis-for-body-weight-management
#8
Mesfin Yimam, Ping Jiao, Mei Hong, Lidia Brownell, Young-Chul Lee, Hyun-Jin Kim, Jeong-Bum Nam, Mi-Ran Kim, Qi Jia
Obesity is the largest and fastest growing public health catastrophe in the world affecting both adults and children with a prevalence impacting more than one-third of United States (US) adult population. Although the long-term solution lies in lifestyle changes in the form of dieting and exercise, intervention is required for those who are already obese. Unfortunately, treatment options remain quite limited due to associated side effects of conventional therapeutics. As a natural alternative, in this study we describe the beneficial effect of a standardized composition (UP603) comprised of extracts from Morus alba, Ilex paraguariensis, and Rosmarinus officinalis in improving metabolic disorders in high fat diet (HFD) and high fat & high fructose diet (HFFD) induced obese C57BL/6J mice...
July 14, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28704534/short-term-variation-in-ntprobnp-after-lifestyle-intervention-in-severe-obesity
#9
Debora Fedele, Virginia Bicchiega, Alessandro Collo, Federica Barutta, Erika Pistone, Gabriella Gruden, Graziella Bruno
AIM: Natriuretic peptides are not only involved in cardiovascular adaption to various conditions, but also in metabolic diseases. We performed this study to assess the effect of a very short time of lifestyle inpatient intervention on NTproBNP values in normotensive subjects with severe obesity and normal cardiac function. METHODS: We recruited 14 consecutive obese normotensive subjects with normal cardiac function who were aged 30 years and more and were referred to inpatient rehabilitation in an academic clinic over a two months period...
2017: PloS One
https://www.readbyqxmd.com/read/28702436/paternal-physical-exercise-improves-spatial-learning-ability-by-enhancing-hippocampal-neuroplasticity-in-male-pups-born-from-obese-maternal-rats
#10
Hye-Sang Park, Tae-Woon Kim
Maternal obesity exerts negative effects on cognitive function and behavior of the offspring. In the present study, we assessed the effects of paternal physical exercise on spatial learning ability in relation with hippocampal neuroplasticity in the rat pups born from the obese maternal rats. There were four experimental groups: paternal nonexercised male pups from normal maternal rats, paternal exercised male pups from normal maternal rats, paternal nonexercised male pups from obese maternal rats, and paternal exercised male pups from obese maternal rats...
June 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28702218/effects-of-a-parallel-arm-randomized-controlled-weight-loss-pilot-study-on-biological-and-psychosocial-parameters-of-overweight-and-obese-breast-cancer-survivors
#11
Andrea Y Arikawa, Beth C Kaufman, Susan K Raatz, Mindy S Kurzer
BACKGROUND: Weight gain often occurs after breast cancer (BC) diagnosis and obesity along with sedentary behavior are associated with increased risk of BC recurrence and mortality. The primary objective of this study was to determine whether a significant weight loss, of approximately 10%, would lead to beneficial changes in biomarkers associated with cancer and/or cancer recurrence, and quality of life (QOL) in overweight and obese BC survivors. METHODS: This parallel-arm study took place in Minneapolis, Minnesota, from January 2009 until March 2010...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28695445/parental-and-child-factors-associated-with-under-estimation-of-children-with-excess-weight-in-spain
#12
Ingrid de Ruiter, Rocío Olmedo-Requena, José Juan Jiménez-Moleón
Objective Understanding obesity misperception and associated factors can improve strategies to increase obesity identification and intervention. We investigate underestimation of child excess weight with a broader perspective, incorporating perceptions, views, and psychosocial aspects associated with obesity. Methods This study used cross-sectional data from the Spanish National Health Survey in 2011-2012 for children aged 2-14 years who are overweight or obese. Percentages of parental misperceived excess weight were calculated...
July 10, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28692066/genotype-covariate-interaction-effects-and-the-heritability-of-adult-body-mass-index
#13
Matthew R Robinson, Geoffrey English, Gerhard Moser, Luke R Lloyd-Jones, Marcus A Triplett, Zhihong Zhu, Ilja M Nolte, Jana V van Vliet-Ostaptchouk, Harold Snieder, Tonu Esko, Lili Milani, Reedik Mägi, Andres Metspalu, Patrik K E Magnusson, Nancy L Pedersen, Erik Ingelsson, Magnus Johannesson, Jian Yang, David Cesarini, Peter M Visscher
Obesity is a worldwide epidemic, with major health and economic costs. Here we estimate heritability for body mass index (BMI) in 172,000 sibling pairs and 150,832 unrelated individuals and explore the contribution of genotype-covariate interaction effects at common SNP loci. We find evidence for genotype-age interaction (likelihood ratio test (LRT) = 73.58, degrees of freedom (df) = 1, P = 4.83 × 10(-18)), which contributed 8.1% (1.4% s.e.) to BMI variation. Across eight self-reported lifestyle factors, including diet and exercise, we find genotype-environment interaction only for smoking behavior (LRT = 19...
July 10, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28689444/ethnic-variations-on-gestational-diabetes-mellitus-and-evidence-based-first-line-interventions
#14
Joy Blumberg, Victoria Ballares, Jessica L Durbin
PURPOSE/OBJECTIVES: To analyze the cultural and ethnic impact of gestational diabetes mellitus (GDM), report the associated complications, and investigate how lifestyle interventions are effective in preventing these associated complications. METHODS: A literature review was conducted using online databases like CINAHL and Cochrane review. Findings were limited to journal articles published between 2012 and 2017. Irrelevant and relevant articles were determined by research topic, specific population, and type of interventions...
July 10, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28685623/cardiovascular-disease-prevention-strategies-for-type-2-diabetes-mellitus
#15
Niki Katsiki, Francesco Purrello, Costas Tsioufis, Dimitri P Mikhailidis
Type 2 diabetes mellitus (T2DM) is associated with several cardiovascular (CV) risk factors such as insulin resistance, obesity, hypertension, dyslipidaemia, non-alcoholic fatty liver disease as well as platelet and haemostatic abnormalities increasing the risk of thrombosis. Therefore, T2DM patients are at an increased risk for CV disease (CVD). Areas covered: This narrative review discusses the treatment of T2DM. This includes lifestyle measures (diet, exercise and smoking cessation) as well as hypolipidaemic, antihypertensive, weight reducing, antiplatelet and glucose lowering drugs...
July 7, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28682864/characterization-of-lipid-profile-by-nuclear-magnetic-resonance-spectroscopy-1h-nmr-of-metabolically-healthy-obese-women-after-weight-loss-with-mediterranean-diet-and-physical-exercise
#16
Enrique Rodriguez-Garcia, Josefina Ruiz-Nava, Sonia Santamaria-Fernandez, Jose Carlos Fernandez-Garcia, Antonio Vargas-Candela, Raquel Yahyaoui, Francisco J Tinahones, Maria Rosa Bernal-Lopez, Ricardo Gomez-Huelgas
Obesity is associated with an atherogenic lipid profile. No data exists on lipoprotein particle profiles in metabolically healthy obese (MHO) individuals. Our aim is to characterize lipoprotein size, particle, and subclass concentrations in MHO women after 3 months of weight loss through dietary restriction and physical exercise.A total of 115 nondiabetic women (aged 35-55 years) with a body mass index (BMI) of 30 to 40 kg/m and ≤1 of the following criteria: blood pressure ≤135/85 mm Hg, fasting plasma glucose ≤100 mg/dL, HDL-cholesterol ≤50 mg/dL, and triglycerides ≤150 mg/dL were included...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28679623/high-but-not-low-exercise-volume-shifts-the-balance-of-renin-angiotensin-system-towards-ace2-mas-receptor-axis-in-skeletal-muscle-in-obese-rats
#17
Eliete Dalla Corte Frantz, Isabele Gomes Giori, Marcus Vinícius Machado, D'Angelo Carlo Magliano, Fernanda Marques Freitas, Mariana Sodré Boêta Andrade, Aline Bomfim Vieira, Antonio Claudio Lucas Claudio Lucas da Nóbrega, Eduardo Tibirica
Metabolic Syndrome (MS) is a cluster of metabolic risk factors which is linked to central obesity, elevated blood pressure, insulin resistance (IR) and dyslipidemia, where the rennin-angiotensin system (RAS) may provide a link among them. This study aimed to evaluate volume exercise effects comparing low versus high volume of chronic aerobic exercise on RAS axes in skeletal muscle in a diet-induced obesity (DIO) rat model. For this, male Wistar-Kyoto rats were fed a standard chow diet (SC) or a high-fat diet (HF) for 32 weeks...
July 5, 2017: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28677175/s1-guidelines-lipedema
#18
Stefanie Reich-Schupke, Wilfried Schmeller, Wolfgang Justus Brauer, Manuel E Cornely, Gabriele Faerber, Malte Ludwig, Gerd Lulay, Anya Miller, Stefan Rapprich, Dirk Frank Richter, Vivien Schacht, Klaus Schrader, Markus Stücker, Christian Ure
The present, revised guidelines on lipedema were developed under the auspices of and funded by the German Society of Phlebology (DGP). The recommendations are based on a systematic literature search and the consensus of eight medical societies and working groups. The guidelines contain recommendations with respect to diagnosis and management of lipedema. The diagnosis is established on the basis of medical history and clinical findings. Characteristically, there is a localized, symmetrical increase in subcutaneous adipose tissue in arms and legs that is in marked disproportion to the trunk...
July 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28671558/brain-functional-connectivity-is-modified-by-a-hypocaloric-mediterranean-diet-and-physical-activity-in-obese-women
#19
Natalia García-Casares, María R Bernal-López, Nuria Roé-Vellvé, Mario Gutiérrez-Bedmar, Jose C Fernández-García, Juan A García-Arnés, José R Ramos-Rodriguez, Francisco Alfaro, Sonia Santamaria-Fernández, Trevor Steward, Susana Jiménez-Murcia, Isabel Garcia-Garcia, Pedro Valdivielso, Fernando Fernández-Aranda, Francisco J Tinahones, Ricardo Gómez-Huelgas
Functional magnetic resonance imaging (fMRI) in the resting state has shown altered brain connectivity networks in obese individuals. However, the impact of a Mediterranean diet on cerebral connectivity in obese patients when losing weight has not been previously explored. The aim of this study was to examine the connectivity between brain structures before and six months after following a hypocaloric Mediterranean diet and physical activity program in a group of sixteen obese women aged 46.31 ± 4.07 years...
July 1, 2017: Nutrients
https://www.readbyqxmd.com/read/28668407/current-and-cutting-edge-interventions-for-the-treatment-of-obese-patients
#20
REVIEW
Jenanan Vairavamurthy, Lawrence J Cheskin, Dara L Kraitchman, Aravind Arepally, Clifford R Weiss
The number of people classified as obese, defined by the World Health Organization as having a body mass index ≥30, has been rising since the 1980s. Obesity is associated with comorbidities such as hypertension, diabetes mellitus, and nonalcoholic fatty liver disease. The current treatment paradigm emphasizes lifestyle modifications, including diet and exercise; however this approach produces only modest weight loss for many patients. When lifestyle modifications fail, the current "gold standard" therapy for obesity is bariatric surgery, including Roux-en-Y gastric bypass, sleeve gastrectomy, duodenal switch, and placement of an adjustable gastric band...
August 2017: European Journal of Radiology
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