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https://www.readbyqxmd.com/read/28914527/locally-induced-adipose-tissue-browning-by-microneedle-patch-for-obesity-treatment
#1
Yuqi Zhang, Qiongming Liu, Jicheng Yu, Shuangjiang Yu, Jinqiang Wang, Li Qiang, Zhen Gu
Obesity is one of the most serious public health problems in the 21st century that may lead to many comorbidities such as type-2 diabetes, cardiovascular diseases, and cancer. Current treatments toward obesity including diet, physical exercise, pharmacological therapy, as well as surgeries are always associated with low effectiveness or undesired systematical side effects. In order to enhance treatment efficiency with minimized side effects, we developed a transcutaneous browning agent patch to locally induce adipose tissue transformation...
September 15, 2017: ACS Nano
https://www.readbyqxmd.com/read/28914104/influence-of-previous-body-mass-index-and-sex-on-regional-fat-changes-in-a-weight-loss-intervention
#2
Pedro J Benito, Rocio Cupeiro, Ana B Peinado, Miguel A Rojo, Nicola Maffulli
OBJECTIVES: Men and women may lose weight in a different fashion. This study compares the changes in different anatomical regions after a well-controlled weight loss program by sex and initial BMI. METHODS: A total of 180 subjects (48 overweight women, 36 overweight men, and 48 obese women and 48 obese men) were recruited to participate in a 22-week weight loss programme (diet + exercise). RESULTS: Regarding percentage body weight change from baseline, there was no triple interaction (BMI, sex and anatomical region), but there was interaction between BMI and anatomical region (F2,840=34...
September 15, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28913977/the-effect-of-diet-or-exercise-on-ectopic-adiposity-in-children-and-adolescents-with-obesity-a-systematic-review-and-meta-analysis
#3
REVIEW
W Hens, D Vissers, D Hansen, S Peeters, J Gielen, L Van Gaal, J Taeymans
OBJECTIVE: Ectopic fat depostion in youth with obesity is associated with an increased cardiovascular disease risk. The aim of this meta-analysis was to summarize the evidence for the use of diet and/or exercise on ectopic adiposity in this population. METHODS: A systematic literature search was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis statement. Clinical trials that assessed ectopic fat deposition and included study arms with diet and/or exercise were searched in PubMed, PEDro and the Cochrane database...
September 14, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28904705/a-study-to-determine-the-prevalence-and-factors-associated-with-hypertension-among-employees-working-at-a-call-centre-nairobi-kenya
#4
Mwagi Joseph Onyango, Iyeri Kombe, Daniel Sagwe Nyamongo, Moses Mwangi
INTRODUCTION: Hypertension often referred to as Non Communicable Diseases (NCDs). Causes of hypertension are classified into modifiable and non-modifiable factors. The objective of the study was to determine the prevalence and other associated factors leading to the onset of hypertension among employees working at the call center. METHODS: This was a descriptive cross sectional study design. Data collection was done in two parts; part one comprised of clinical health assessments; weight and height to aid determine Body Mass Index and blood pressure measurement...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28894050/compounds-of-psoriasis-with-obesity-and-overweight
#5
Agnieszka Owczarczyk-Saczonek, Waldemar Placek
Many epidemiological studies have confirmed the relationship of obesity and psoriasis, and it is believed that obesity is an independent risk factor for its development and is associated with a worse prognosis. Furthermore, the reduction of body weight, using low-calorie diet combined with exercise, reduces the severity of psoriasis.Visceral adipose tissue is the largest endocrine organ, producing proinflammatory cytokines (TNF-α, IL-6, IL-17) and adipokines (adiponectin, omentin, chemerin). They participate in the development of dyslipidemia, insulin resistance, diabetes, and consequently of the cardiovascular diseases...
August 24, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28891296/non-invasive-body-fat-burn-monitoring-from-exhaled-acetone-with-si-doped-wo3-sensing-nanoparticles
#6
Andreas T Güntner, Noriane A Sievi, S Jonathan Theodore, Tobias Gulich, Malcolm Kohler, Sotiris E Pratsinis
Obesity is a global health threat on the rise and its prevalence continues to grow. Yet suitable biomedical sensors to monitor the body fat burn rates in situ to guide physical activity or dietary interventions toward efficient weight loss are missing. Here, we introduce a compact and inexpensive breath acetone sensor based on Si-doped WO3 nanoparticles that can accurately follow body fat burn rates in real-time. We tested this sensor on 20 volunteers during exercise and rest and measured their individual breath acetone concentrations in good agreement to bench-top proton transfer reaction time-of-flight mass spectrometry (PTR-TOF-MS)...
September 11, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28888511/the-influence-of-peers-on-diet-and-exercise-among-adolescents-a-systematic-review
#7
REVIEW
Sophia Jihey Chung, Anne L Ersig, Ann Marie McCarthy
Adolescents' diet and exercise are modifiable factors contributing to high rates of adolescent obesity. Diverse contextual factors, including family, social environment, and peers, affect adolescents' diet and exercise behaviors. Because peer influence increases during adolescence, peers' contributions to adolescents' diet and exercise behaviors should be examined as potential targets for intervention to reduce the prevalence of adolescent obesity. The purpose of this systematic review is to identify research examining the contribution of peers to diet and exercise of adolescents...
September 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28887090/vitamin-c-partially-prevents-reproductive-damage-in-adult-male-rats-exposed-to-rosuvastatin-during-prepuberty
#8
Gabriel Adan Araújo Leite, Thamiris Moreira Figueiredo, Tainá Louise Pacheco, Marciana Sanabria, Patrícia Villela E Silva, Fábio Henrique Fernandes, Wilma De Grava Kempinas
Pediatric obesity is closely associated with dyslipidemias and environmental factors, such as diet and lack of physical exercises, which may alter lipid profile in children. Rosuvastatin decreases serum total cholesterol and triglycerides concentrations. Vitamin C (ascorbic acid) plays an important role on sperm integrity and fertility. Juvenile male rats were distributed into six experimental groups that received saline solution 0.9%, 3 or 10 mg/kg/day of rosuvastatin, 150 mg/day of ascorbic acid, or 3 or 10 mg/kg/day of rosuvastatin co-administered with 150 mg/day of ascorbic acid from PND23 until PND53 and then the rats were maintained until sexual maturity...
September 6, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28875050/development-and-evaluation-of-an-obesity-ontology-for-social-big-data-analysis
#9
Ae Ran Kim, Hyeoun-Ae Park, Tae-Min Song
OBJECTIVES: The aim of this study was to develop and evaluate an obesity ontology as a framework for collecting and analyzing unstructured obesity-related social media posts. METHODS: The obesity ontology was developed according to the 'Ontology Development 101'. The coverage rate of the developed ontology was examined by mapping concepts and terms of the ontology with concepts and terms extracted from obesity-related Twitter postings. The structure and representative ability of the ontology was evaluated by nurse experts...
July 2017: Healthcare Informatics Research
https://www.readbyqxmd.com/read/28874980/prevalence-and-risk-factors-for-low-back-pain-in-1-355-young-adults-a-cross-sectional-study
#10
Sudhir Ganesan, Anita Shankar Acharya, Ravi Chauhan, Shankar Acharya
STUDY DESIGN: Cross-sectional study. PURPOSE: To evaluate the prevalence and various risk factors for low back pain (LBP) in young adults in India. OVERVIEW OF LITERATURE: LBP is an emerging problem in adolescents, with an incidence that is the highest in the third decade of life worldwide. Various risk factors such as obesity, smoking, family history, stress, and exercise have been described in the literature. This study was conducted because of paucity of data in the Indian literature...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28864989/the-long-term-effects-of-the-periconceptional-period-on-embryo-epigenetic-profile-and-phenotype-the-paternal-role-and-his-contribution-and-how-males-can-affect-offspring-s-phenotype-epigenetic-profile
#11
Emma S Lucas, Adam J Watkins
The number of adults afflicted with heart disease, obesity and diabetes, central components of metabolic disorder, has grown rapidly in recent decades, affecting up to one quarter of the world's population. Typically, these diseases are attributed to lifestyle factors such as poor diet, lack of exercise and smoking. However, studies have now identified strong associations between patterns of growth during foetal and neonatal life and an increase predisposition towards developing heart disease, obesity and diabetes in adult life...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28862123/results-of-1-year-diet-and-exercise-interventions-for-er-pr%C3%A2-her2-breast-cancer-patients-correlated-with-treatment-type
#12
Diana V Artene, Cristian I Bordea, Alexandru Blidaru
PURPOSE: Many breast cancer patients gain weight during chemotherapy and antiestrogenic treatment increasing recurrence, oncologic specific and all-cause mortality risks. Patients and Methods: 165 ER+/PR±/HER2- breast cancer patients under antiestrogenic treatment were randomly assigned to follow an at-home diet based on food naturally high in proteins, calcium, probiotics and prebiotics (D), or this diet and 4' isometric exercises (D+Ex) for 1 year. We measured weight (W), body (BF) and visceral fat (VF) using a multi-frequency bioelectrical impedance scale on the 6th and 12th month and we correlated results with chemotherapy, surgery and antiestrogenic medication type...
July 2017: Chirurgia
https://www.readbyqxmd.com/read/28860773/can-melatonin-prevent-or-improve-metabolic-side-effects-during-antipsychotic-treatments
#13
Maria-Cristina Porfirio, Juliana Paula Gomes de Almeida, Maddalena Stornelli, Silvia Giovinazzo, Diane Purper-Ouakil, Gabriele Masi
In the last two decades, second-generation antipsychotics (SGAs) were more frequently used than typical antipsychotics for treating both psychotic and nonpsychotic psychiatric disorders in both children and adolescents, because of their lower risk of adverse neurological effects, that is, extrapyramidal symptoms. Recent studies have pointed out their effect on weight gain and increased visceral adiposity as they induce metabolic syndrome. Patients receiving SGAs often need to be treated with other substances to counteract metabolic side effects...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28857453/prior-endurance-training-enhances-beta-adrenergic-signaling-in-epidydimal-adipose-from-mice-fed-a-high-fat-diet
#14
Laelie A Snook, Sarah K Trottier, Elizabeth A Worndl, Eric Bombardier, A Russell Tupling, Rebecca E K MacPherson
OBJECTIVE: Adipose tissue beta-adrenergic signaling is attenuated in obesity and insulin resistance. It has been previously demonstrated that prior exercise training protects against short-term, high-fat diet (HFD)-induced weight gain and glucose intolerance. This study aimed to determine whether prior exercise training results in altered beta-adrenergic and lipolytic signaling in adipose tissue when challenged with a HFD. METHODS: Male C57BL/6J mice underwent 4 weeks of treadmill training (1 h/d, 5 d/wk)...
August 31, 2017: Obesity
https://www.readbyqxmd.com/read/28855180/diet-induced-obesity-accelerates-blood-lactate-accumulation-of-rats-in-response-to-incremental-exercise-to-maximum
#15
Chiao-Nan Joyce Chen, Yi-Hung Liao, Shang-Ying Lin, Jun-Xian Yu, Zhen-Jie Li, Yu-Chieh Lin, Gwo-Jyh Chang, Chung-Hao Lin, Alice May-Kuen Wong
AIM: Blood lactate increases during incremental exercise at high-intensity workloads and limited exercise capacity is a characteristic of obese animals. This study examined whether blood lactate changes in response to incremental exercise is disrupted in obese animals. Muscular and hepatic proteins that are critical in lactate metabolism were also investigated. METHODS: Rats were randomized to either standard chow (control) or high fat diet (HFD) groups. All animals underwent an incremental treadmill test after 14 weeks of diet intervention...
August 30, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28854149/chronic-exercise-reduces-hypothalamic-transforming-growth-factor-%C3%AE-1-in-middle-aged-obese-mice
#16
Vagner R R Silva, Carlos K Katashima, Luciene Lenhare, Carla G B Silva, Joseane Morari, Rafael L Camargo, Licio A Velloso, Mario A Saad, Adelino S R da Silva, Jose Rodrigo Pauli, Eduardo Rochete Ropelle
Obesity and aging are associated with hypothalamic inflammation, hyperphagia and abnormalities in the thermogenesis control. It has been demonstrated that the association between aging and obesity induces hypothalamic inflammation and metabolic disorders, at least in part, through the atypical hypothalamic transforming growth factor-β (TGF-β1). Physical exercise has been used to modulate several metabolic parameters. Thus, the aim of this study was to evaluate the impact of chronic exercise on TGF-β1 expression in the hypothalamus of Middle-Aged mice submitted to a one year of high-fat diet (HFD) treatment...
August 28, 2017: Aging
https://www.readbyqxmd.com/read/28843495/high-intensity-interval-versus-moderate-intensity-continuous-training-superior-metabolic-benefits-in-diet-induced-obesity-mice
#17
Ningning Wang, Yang Liu, Yanan Ma, Deliang Wen
AIMS: Exercise is beneficial in obesity, however, the debate about the value of high-intensity interval training (HIIT) vs. moderate-intensity continuous training (MICT) has been long lasting. Therefore, here we have compared the possible beneficial effects of two different exercise training regimes in a mouse model of diet-induced obesity (DIO). MATERIALS AND METHODS: Following 7wk. on high fat diet (HFD), ten-week-old male ICR mice (n=30) were assigned to HIIT, distance-matched MICT or remained sedentary for the next 8 constitutive weeks while maintaining the dietary treatments...
August 23, 2017: Life Sciences
https://www.readbyqxmd.com/read/28837820/an-experiment-assessing-effects-of-personalized-feedback-about-genetic-susceptibility-to-obesity-on-attitudes-towards-diet-and-exercise
#18
Woo-Kyoung Ahn, Matthew S Lebowitz
As increasing attention is paid to possible genetic influences on susceptibility to obesity, recent studies have examined how genetic attributions can impact laypeople's weight-related attitudes and eating behavior. Little consideration, however, has been devoted to understanding the potential effects of learning that one does not have a genetic predisposition to obesity. The present study investigated the possibility that such feedback might bring about negative consequences by making people feel invulnerable to weight gain, which is termed a genetic invincibility effect...
August 25, 2017: Appetite
https://www.readbyqxmd.com/read/28836274/interconception-care-for-women-with-a-history-of-gestational-diabetes-for-improving-maternal-and-infant-outcomes
#19
REVIEW
Joanna Tieu, Emily Shepherd, Philippa Middleton, Caroline A Crowther
BACKGROUND: Gestational diabetes mellitus (GDM) is associated with adverse health outcomes for mothers and their infants both perinatally and long term. Women with a history of GDM are at risk of recurrence in subsequent pregnancies and may benefit from intervention in the interconception period to improve maternal and infant health outcomes. OBJECTIVES: To assess the effects of interconception care for women with a history of GDM on maternal and infant health outcomes...
August 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28831733/pre-surgical-pulmonary-rehabilitation-in-asthma-patients-undergoing-bariatric-surgery
#20
Yasemin Türk, Astrid van Huisstede, Pieter S Hiemstra, Christian Taube, Gert-Jan Braunstahl
This pilot study was performed to investigate the feasibility of pre-surgical pulmonary rehabilitation (PR) in morbidly obese patients with uncontrolled asthma, undergoing bariatric surgery. Four morbidly obese female patients with asthma participated in a 12-week PR program (exercise, diet, and psychological intervention) before undergoing bariatric surgery, and the outcomes were compared to a matched group of seven female controls (bariatric surgery only). In patients who participated in PR, asthma control and asthma quality of life improved dramatically after 3 months of PR...
August 22, 2017: Obesity Surgery
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